Feb 2018 Exam

Recalls Feb Exam 2018
1- Hexamine Hippurate can be use with

a. Ascorbic acid
b. Asprin
c. Thiamine
d. Vit D.
2-Aspirin over dosage toxicity can be managed by

a. EDTA
b. Charcoal
c. Deferasirox
d. Desferrioxamin
e. Deferipron
3-In TB which drug can use as enzyme induce inhibitors

a. INH
b. Rifampicin
c. P450
INH is inhibitor
Rifampicin is inducer
4-Mianserin ?? TCA antidepressants
5-Analgesic does not have active metabolites form

a. Paracetamol
b. Morphine
c. Aspirin
d. Codeine
6-Calculation of paracetamol dosage of 2 to 8 years 15mg/kg 4 times daily

7-Clostridum difficile disease ttt
a. Metronidazole
b. Penicillin
c. Clindamycin
8-Which of the following is stored at 2-8 c

Flucloxacillin susp yes
9-A 10 mL ampoule of potassium chloride injection contains 1.49 grams of potassium

chloride. What is the concentration of potassium ions in this solution?
(molecular weight of potassium chloride = 74.5)
A 0.2 mmol/mL
B 1 mmol/mL
C 2 mmol/mL
D 10 mmol/mL
E 20 mmol/mL
10-The compound with the following structure is (_)-3-(3,4-dihydroxyphenyl)-L-alanine.
Select the most appropriate statement below.

A the compound is adrenaline
B it is a dextrorotatory compound
C it is a precursor of dopamine
D it is used to treat hypertension
E it is an essential amino acid
11-The chemical formula above represents
A aspirin
B methyl salicylate
C salicylic acid
D salicylamide
E methyl-2-hydroxysalicylate
12-An antibiotic which has a half-life of one year is formulated as a 200 mg tablet.
How many milligrams of antibiotic would remain after three years? As this Q but with different
numbers
A 25
B 50
C 100
D 150
E 200
13-which of the following is ion present in vitamine B12?
a. Ferrous
b. cobalt
c. magnesium
d. calcium
14-What is the dose of atropine?
A. 20 to 200 microgram
B.2 to 20 mg
C.0.2 to 2 mg
D.20 to 200 mg
15-Precursor of erythrocytes : Reticulocytes yes
16-Erythropoetins are glycoprotein produced through recombinant DNA technology yes
17-Hemoglobin (Hgb): Blood protein yes
18-1, 25-dihydroxycholecalciferol its name:calcitriol yes
19-Clindamycin-induce diarrhea may be the result of Pseudomembranous colitis yes
20-To calculate loading dose
21-Epoprostenol: PGE1 analog , It produces antiplatelets action. yes
22-Glucocorticoids main function : one of the answers is intermediate in metabolism so I choose

it yes
23-Canal of schlemm its function :collects aqueous humor yes
24-Q on GLC (Gas Liquid Chromatography) method of separation contain mobile phase and
stationary phase
25- Cardiotoxicity commonly seen with doxorubicin, daunorubicin yes
26-Deoxygenated blood enters the heart through:
27-Oxygenated blood moves inside the heart in which structure B then D then A then C
A-Right atrium
B-Left atrium if it is for heart
C-Right ventricle
D-Left ventricle if it is for body
28- Q on Anatomy of the intestine: dobenum, jejinum, illeum
29- Q on Pseudoplastic flow & thixotropic
Shear thining called pseudo plastic and thixotropy, decrease in viscosity
Shear thickening called dilatancy or rheopexy, increase in viscosity

30- which of the following can be crushed:
a. diclofenac
b. alendronate
c. carvedilol,
d. cyproheptadine
31- Which one of these does not have an active metabolite
a. Sertraline
b. Ramipril
c. Phenytoin
d. aspirin
e. morphine
f. fluoxetine
32- Acarbose max dose 600 mg per day
33- A lot of Q the answer is Metformin so metformin is used in what type of
diabetic pt
34- Creutzfeldt–Jakob disease deficiency in ---- deacrease in mental function caused by prions (kind
og protein cayse foded protein to be misfolded), defincicy in ???
35- A lot of Q about hypokalemia & hyperkalemia
36-Problem about clearance =vdk

37- Which is NOT true for the substance with the following chemical structure?
The name of the drug isn’

t written since the Q on it
A insoluble in water
B used as a topical, local anaesthetic
C a benzoic acid derivative
D readily hydrolysed in boiling water
E insoluble in mineral acids

38-Which of the following therapeutic classifications does the chemical structure above
belong to?
A tranquilliser
B anti-infective
C antihistamine
D analgesic
E antidiuretic
39- The compound with the following structure is a hormone
By which of the following is this hormone secreted?
A corpus luteum (it is progesterone)
B testis
C posterior pituitary
D anterior pituitary
E pancreas
40- The major determinant of myocardial oxygen consumption is
A heart rate
B diastolic blood pressure
C cardiac output
D blood volume
E myocardial fibre tension

41- Sodium chloride equivalents are used to estimate the amount of sodium chloride
needed to render a solution isotonic. The sodium chloride equivalent
or "E" value may be defined as the
A amount of sodium chloride that is theoretically
equivalent to one gram of a specified chemical
B amount of a specified chemical theoretically equivalent to one
gram of sodium chloride
C milliequivalents of sodium chloride needed to render a solution
isotonic
D weight of a specified chemical that will render a solution isotonic
E percent sodium chloride needed to make a solution
Isotonic
42- The probenecid increases the ampicillin's duration of action by altering
A renal tubular reabsorption
B renal tubular secretion
C glomerular filtration
D intestinal absorption
E hepatic metabolism
All pencilline excerted by active tubual secretion ,
43-NSAIDs:
a. all have antipyretic properties
b. block production of PGs, Tromboxane and Leukotrien
c. exert their anti-inflammatory properties by blocking COX-1

44-enantiomer, which statement is not true?
a. all of them have a chiral carbon
b. have different physical properties
c. enantiomers react with chiral reactants
d. enantiomers don’
t react with achiral reactant
45-who reduces the threshold of seizures?
a. tramadol
b. morphine
c. fentanyl
d. oxycodone
46-Digoxin (t 1/2 36h) given daily reaches steady state after :
a. 6 days
b. 8 days
c. 10 days
47- Mech of action of digoxin
Repeated different Q on ACEI, NSAIDS, Clostridium Difficile, Acarbose, Metformin ,

vancomycin , Acetaminophin, Digoxin

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Recalls Feb Exam 2018

1- Hexamine Hippurate can be use with

2-Aspirin over dosage toxicity can be managed by

3-In TB which drug can use as enzyme induce inhibitors

4-Mianserin ?? TCA antidepressants

5-Analgesic does not have active metabolites form

6-Calculation of paracetamol dosage of 2 to 8 years 15mg/kg 4 times daily

8-Which of the following is stored at 2-8 c

9-A 10 mL ampoule of potassium chloride injection contains 1.49 grams of potassium

10-The compound with the following structure is (_)-3-(3,4-dihydroxyphenyl)-L-alanine.

Select the most appropriate statement below.

13-which of the following is ion present in vitamine B12?

14-What is the dose of atropine?

15-Precursor of erythrocytes : Reticulocytes yes

16-Erythropoetins are glycoprotein produced through recombinant DNA technology yes

17-Hemoglobin (Hgb): Blood protein yes

18-1, 25-dihydroxycholecalciferol its name:calcitriol yes

19-Clindamycin-induce diarrhea may be the result of Pseudomembranous colitis yes

20-To calculate loading dose

21-Epoprostenol: PGE1 analog , It produces antiplatelets action. yes

22-Glucocorticoids main function : one of the answers is intermediate in metabolism so I choose

23-Canal of schlemm its function :collects aqueous humor yes

25- Cardiotoxicity commonly seen with doxorubicin, daunorubicin yes

26-Deoxygenated blood enters the heart through:

B-Left atrium if it is for heart

D-Left ventricle if it is for body

28- Q on Anatomy of the intestine: dobenum, jejinum, illeum

29- Q on Pseudoplastic flow & thixotropic

Shear thining called pseudo plastic and thixotropy, decrease in viscosity

Shear thickening called dilatancy or rheopexy, increase in viscosity

31- Which one of these does not have an active metabolite

32- Acarbose max dose 600 mg per day

33- A lot of Q the answer is Metformin so metformin is used in what type of

36-Problem about clearance =vdk

The name of the drug isn’

B used as a topical, local anaesthetic

C a benzoic acid derivative

D readily hydrolysed in boiling water

E insoluble in mineral acids

By which of the following is this hormone secreted?

A corpus luteum (it is progesterone)

40- The major determinant of myocardial oxygen consumption is

B diastolic blood pressure

E myocardial fibre tension

needed to render a solution isotonic. The sodium chloride equivalent

or "E" value may be defined as the

A amount of sodium chloride that is theoretically

equivalent to one gram of a specified chemical

B amount of a specified chemical theoretically equivalent to one

gram of sodium chloride

C milliequivalents of sodium chloride needed to render a solution

D weight of a specified chemical that will render a solution isotonic

E percent sodium chloride needed to make a solution

42- The probenecid increases the ampicillin's duration of action by altering

A renal tubular reabsorption

B renal tubular secretion

All pencilline excerted by active tubual secretion ,

a. all have antipyretic properties

b. block production of PGs, Tromboxane and Leukotrien

c. exert their anti-inflammatory properties by blocking COX-1