ROTR 2018 Ecosystem Playbook

RISE OF THE REST
2018 ECOSYSTEM
PLAYBOOK INSIGHTS + IDEAS
FROM REGIONAL CITIES
POWERED BY @RiseOfRest www.revolution.com/rotr

Contents
INTRODUCTION
INSIGHT 01 INSIGHT 02 INSIGHT 03 INSIGHT 04

CONNECTING + LEVERAGING FOSTERING PROMOTING
CONVENING YOUR UNIVERSITY INNOVATION PARTNERSHIPS
COMMUNITY RESOURCES WITH PUBLIC FROM REGIONAL
POLICIES + CORPORATIONS +
PHOENIX DURHAM PROGRAMS LOCAL INDUSTRY
The PHX Startup Duke I&E Contributes
Ecosystem: 7 Things to to Durham’s Growing NASHVILLE CINCINNATI
Do in Your First 60 Days Entrepreneurial Scene Tennessee Proactively The Brandery & Big
Pursues Startup-Friendly Companies: How Cincinnati
DENVER BALTIMORE Status Fosters Partnerships that Work
Tapping into the Local Magic Johns Hopkins’ Role in
Bringing the Benefit of CHARLESTON ATLANTA
SALT LAKE CITY Discovery to the World Public Support Engage: 10 BigCos
The Secret Sauce to for Entrepreneurs Back Atlanta-Based
Utah’s Startup Ecosystem MINNEAPOLIS Accelerator & Venture Fund
University of Minnesota’s BUFFALO
DES MOINES Venture Center: Help Launch Public Support in the DES MOINES
5 Quick Tips to Get Connected 100 Startups in 10 Years City of Good Neighbors Iowa Accelerators Focus
on AgTech and Insurance
NASHVILLE
The Wond’ry: Innovation
on Campus at Vanderbilt
University
MADISON
Innovation Initiative
at the University of
Wisconsin–Madison
The following insights were provided by regional ecosystem leaders and originally published as blog posts on the Rise of the Rest website in 2017. The views expressed herein are solely
those of the authors and not necessarily of Rise of the Rest or any of its affiliates. This is not a solicitation to invest in any of the mentioned companies or in Rise of the Rest Seed Fund, LP.
1 / Rise of the Rest 2018 Ecosystem Playbook

Introduction
01 Connecting + Convening Your Community
02 Leveraging University Resources
03 Fostering Innovation with
Public Policies + Programs
04 Promoting Partnerships from Regional
Corporations + Local Industry
INTRODUCTION
2 / Rise of the Rest 2018 Ecosystem Playbook / Introduction

A Letter from Steve Case
S
ince 2014, we have visited 33 cities outside of Silicon Valley,
New York and Boston, traveling more than 8,000 miles over
6 bus tours. After each tour, I am reminded that 75 years ago
Detroit was once our nation’s mecca for fast growing businesses
and new ideas. Back then Silicon Valley was just fruit orchards.
Cities evolve. Regions rise — and fall. But the desire to build strong
communities and healthy economies remains the same. We see that
in action in every city we visit. These are great American cities, with
storied pasts — but also bright futures, in large part because of the
passionate entrepreneurs building great companies that can create
the jobs and drive the growth for the future.
After each tour, we field the same series of questions: “What did you
learn?” “What makes a city unique?” “Have you seen any ecosystem
patterns emerge?”
To help answer those questions, we have compiled the insights,

experiences and advice from the local stakeholders whom we have
met — and teamed up with while on the road — to spotlight regional
innovation and entrepreneurship.
STEVE CASE

The Seven
Spokes of a
Startup “Hub” Corporations Local
Media
T
hrough our travels, we have found that
there are at least seven entities that help
to fuel the rise of startup ecosystems:
local government, universities, investors,
startup support organizations, corporations, Incubators,
Tent Pole
local media, and the startups themselves. Accelerators,
Companies &
These groups use a variety of levers to help Community
Startups
connect, convene, and support startups. These Builders
efforts, in turn, inspire an environment that is
conducive to innovation and entrepreneurship.
The insights that follow are illustrative of these
regional efforts.
Investors Universities
Local
Government

ROTR Footprint: Tours 1–6
TOURS MILES CITIES
6 8,000 33
Portland, ME
Manchester, NH
Green Bay, WI
Buffalo, NY
Minneapolis, MN Ann Arbor, MI

Harrisburg
Madison, WI Lancaster
Detroit, MI York, PA
Columbus,
Des Moines, IA
OH Philadelphia, PA
Salt Lake City/Provo, UT Lincoln/Omaha, NE Pittsburgh, Baltimore, MD

Indianapolis, IN PA
Cincinnati, OH
Richmond, VA
Kansas City, MO
Denver, CO
Louisville, KY
St. Louis, MO
Raleigh-Durham, NC
Nashville, TN
Albuquerque, NM
Charleston, SC
Phoenix, AZ Atlanta, GA
New Orleans, LA

Introduction
01
Insight
CONNECTING + PHOENIX
The PHX Startup Ecosystem:
7 Things to Do in Your First 60 Days
CONVENING YOUR DENVER

Tapping into the Local Magic
COMMUNITY
SALT LAKE CITY
The Secret Sauce to
Utah’s Startup Ecosystem
DES MOINES
5 Quick Tips to Get Connected
6 / Rise of the Rest 2018 Ecosystem Playbook / Insight 01: Connecting + Convening Your Community
PHOENIX
The PHX Startup Ecosystem:
7 Things To
Do in Your
First 60 Days
By RAOUL ENCINAS
U
ntil a few years ago, the Phoenix
entrepreneur community was separated
into small pockets of talent across the
Valley. Instead of collaborating and working
to improve the ecosystem as a whole, we were
isolated. In 2014, #yesphx was founded to
provide a banner to unify these pockets as one
startup ecosystem.
As part of the #yesphx mission, we also want to

make it easy for anyone to participate. Whether
you’re new to town, a seasoned entrepreneur,
an investor or just intrigued about the concept
of entrepreneurship, you belong here. This is
your community. Your ecosystem. Your people.
Local Motors — Phoenix, AZ, ROTR 5.0, 2016
We know it can be tough to figure out where
to start. That’s what we’re here for. As you dip 2. Attend an Event
your toe into the local startup waters, here are 7
“I thoroughly enjoy going to events,
things a few veteran entrepreneurs recommend
listening to what matters to people, and
doing in your first 60 days to get connected in
connecting them to resources in the
the community.
moment that would make a difference. You
are only three handshakes away from
1. Follow the #yesphx Hashtag anything and everything you want for
yourself and your life.”
“Meaningful content facilitates meaningful
QUINTIN BAKER, Executive Director of
relationships, creates meaningful
Maricopa Center for Entrepreneurship
opportunities, and makes a meaningful
statement for all of Arizona’s entrepreneur There are a number of local events that cater to
ecosystem.” any interest or goal. Whether it’s a weekly staple
like One Million Cups, a monthly program like
JONATHAN COTTRELL,
Startup Grind Phoenix and House of Genius,
Instigator of #yesphx
or a huge annual celebration like PHX Startup
The easiest way to start getting involved is Week, there’s always something going on
by following the #yesphx hashtag on social around town. Plus, local events are a great way
media. As you’ll come to find out, that’s our to meet others face-to-face while you’re at it.
community’s way of staying connected. Watch
Watch the Phoenix Startup Digest calendar to
the conversation on Facebook and Twitter to
see what’s coming up. Here are a few popular
get a feel for what’s trending. Then when you
events and meetups to keep an eye out for:
post something relevant to the community ABOUT THE AUTHOR
(not sales pitches or personal promotions!) PHX Startup Week Startup Phoenix
include #yesphx to collectively amplify what’s Venture Madness CoFoundersLab RAOUL ENCINAS is the Founder
happening around Arizona. 1 Million Cups Matchup of PhosLabs, and he serves clients,
House of Genius Phoenix Mobile communities, and companies who
Startup Grind & IoT Technology crave fresh thinking, new ways
HackerNest Group of leading, and more meaningful
Phoenix impact. As a coach and facilitator,
Internet of Things he helps leaders strengthen their
(IoT) Phoenix entrepreneurial mindset, skillset,
and toolset.
3. Meet Folks Face-to-Face 4. Visit Shared Spaces
“Meet and befriend fired up entrepreneurs, “Shared spaces have a built-in community
angels, investors, and government officials made up of other people passionate about
in the AZ ecosystem. I mean physically be what’s happening in the community. These
in the same room with them, sit next to spaces usually also host all kinds of
them, chat with them, ask them questions, meetups and events as well as have
make connections, tell your story, and treat partnerships or connections with other
PHX Startup Week like one big cocktail local organizations. At CO+HOOTS, we love
party.” welcoming new members, especially those
who are new to Phoenix and want to get
DAN TYRE, Director of Hubspot involved with what’s going on in the
community.”
Community can’t happen without face-to-face
connections. With the wide variety of events on JENNY POON, Founder of CO+HOOTS
a weekly basis, there are ample opportunities
to meet other #yesphx community members. Startups aren’t very territorial when it comes
Don’t be afraid to ask active members to grab to their work environments, which is good for
a coffee or beer to get to know them better. newcomers. There are a growing number of
Nothing beats real connection, and if you amazing shared work spaces all around Greater
want to jumpstart the process, meeting up Phoenix that are great to visit, work from, and,
in person will strengthen your connection to once again, meet others like you. Choosing a
other startup folks pretty quickly. That’s how new work environment is one of the fastest
community is formed. ways to find community. Proximity matters.
Visit the Arizona Commerce Authority’s

directory for a comprehensive list of co-working
and collaborative workspaces in town. Some of
the most established spaces include:
CO+HOOTS Galvanize
The Department Mac6
DeskHub BRIC
SEED SPOT Workuity
Arizona State University — Gangplank
Phoenix, AZ, ROTR 5.0, 2016
5. Learn Something New Education:
“Learning is so important to constant The Knight Foundation
improvement, and we all have something to Entrepreneurship and Innovation
learn from each other. I try to share my at ASU
focus and experiences as much as possible CEI Gateway
with those who can benefit in the Cronkite New Media Innovation
community. I would recommend that other and Entrepreneurship Lab
folks share their expertise and real world Galvanize
examples too, and challenge each other to
Prototype labs:
constantly improve and innovate. Rising
tides lift all boats.” Tallwave
Phoenix Analysis and Design
LINDSAY BAYUK, VP of Product Technologies
Marketing at Pluralsight Coplex
Heat Sync Labs
Learning never ends. Whether you’re starting a Gangplank
new company or growing a mature one, every
day is another opportunity to try something Incubators and programs:
new, test an idea, and grow. Phoenix combines Arizona Commerce Authority’s
the robust educational opportunities that most Incubator and Accelerator directory
big cities offer, but with the openness to sharing Maricopa Innovates
of a close knit community. Take advantage of
VCs:
the knowledge others provide, and consider
reaching out to one of these organizations if Tallwave Capital
you’re interested in brushing up on a new skill, Grayhawk Capital
prototyping a new concept, or accelerating Mrtnz
your company: Sorenson Capital
Canal Partners
Valley Ventures
Arizona Tech Investors
Galvanize
Coplex Ventures
Vivek Kopparthi, Co-founder and CEO of pitch AZ Founders Fund
competition winner NeoLight — Phoenix, AZ,
ROTR 5.0, 2016
6. Treat Everyone Well
“By and large, what I’ve experienced in the
Arizona entrepreneurial ecosystem is an
abundance mindset. There’s a spirit of
generosity here that’s based on goodwill,
peer support, and genuinely wanting to see
others thrive and succeed. Having lived and
worked in both NYC and SF Bay Area,
there’s a level of kindness here that doesn’t
exist elsewhere.”
RAOUL ENCINAS, Founder of PhosLabs
The cornerstone of the #yesphx community

is generosity. This generosity extends beyond
the office and into the personal interactions
we have with each other on a daily basis. This
means we all need to be gracious and kind to
each other, even if there may be times we don’t
see eye to eye. If you’re new to Phoenix’s large
and diverse community of people, please help
us to continue to promote this generosity by
not expecting anything in return when you
contribute, and, quite simply, treating others
how you want to be treated.
WebPT — Phoenix, AZ, ROTR 5.0, 2016
7. Take Ownership
“The startup community depends on a
steady flow of new leaders to step in and
take ownership of different elements of the
ecosystem. This keeps things fresh and
organic. Step in and volunteer at an event,
re-activate a stagnant tech meetup, or
spread the word about the good things
that are happening on your social
channels.”
ZACH FERRES, CEO of Coplex
Becoming an active, contributing, respected

member of a community doesn’t happen
overnight. If you’re looking to truly help,
participate in, and contribute toward building
the world’s most generous community for
entrepreneurs (whatever that may mean to
you), you’ve found a home.
And now that you’re home, help make it a better

place for all. No one person or organization
owns #yesphx; it lives and breathes in the
day-to-day actions, behaviors, and language we
co-create together. That includes you.
Tuft & Needle — Phoenix, AZ, ROTR 5.0, 2016
DENVER
Tapping into
the Local
Magic
By GORDON BRONSON
C
reativity and hungry ambition run
through the veins of Colorado’s capital
city. Nestled at the foot of the Rocky
Mountains, it’s easy to get lost daydreaming
while gazing westward out the window of any
downtown Denver high-rise. But our geography
isn’t the only thing separating The Mile High
City — as we proudly tout from 5,280 feet
above sea level — from other cities on the rise.
Denver is one of the most connected, invested
and supportive communities in which any
entrepreneur could hope to start a company.
Named as the most active city for startups
between the coasts by the U.S. Chamber of
Commerce in 2016, strong networks stretching
across business, philanthropy, politics and
academia help explain why Denver has
matured and cultivated fertile grounds for
young companies to grow.
City Hall — Denver, CO, ROTR 5.0, 2016
What began with a group of committed leaders
driving iconic local industries, from energy to 1. Seek Mentors
telecommunications to aerospace, has grown
The most important professional contact you
into a veritable mecca for burgeoning startups.
can make is a strong mentor. Mentors serve as
Tightly bonded networks transcend superficial
an individual’s board of directors, providing
business card swap meets at happy hour.
guidance through challenges and offering
Creating a network, and the ability to activate it
wisdom from the long road. Effective mentors
takes time and intention.
offer advice; great mentors listen and teach us
Ask any collection of Colorado founders to trust our instincts and find the path that best
and small business supporters and you will fits. There are more than 8 local accelerators
detect a thread of state pride and a strong and incubators where you can look for the right
identity. That understanding of mutual mentor.
success is rooted deep in our ethos. A sense of
community, of connection and faith in others is
helping Denver rise. Here’s how to tap into the 2. Discover Community
local magic:
Denver Startup Week — now the largest
entrepreneurial event in North America,
drawing 12,500 attendees in its 2016 iteration
alone — began with a few friends chatting over
beers about how to leverage and celebrate
Denver, CO, ROTR 5.0, 2016
the city’s budding startup scene. Now, startup
centric festivities happen all over the world. ABOUT THE AUTHOR
Out of those events, new ideas, connections
and concepts for companies materialize every GORDON BRONSON currently
year. Given the opportunity, likeminded folks serves as the Head of Public Affairs
will gravitate toward each other and seek at WeWork, West. When this
opportunities to connect. At the outset, major insight was first published, Gordon
conferences can appear intimidating and was the director of strategic
chaotic; but building a few close relationships communications at Sewald
can prove defining and a future source of Hanfling, a Denver based public
productivity and inspiration. affairs firm. He is veteran of the
Obama administration and several
startups, some more successful
than others.
3. See What the City Has To Offer 4. Give Freely
The city of Denver and state of Colorado are Your time is valuable but so is everyone
no strangers to creative and thoughtful policy- else’s. When it comes to building your own
making, aimed at hacking growth and attracting legacy, think long and hard about the impact
talent. Whether talking about Quarterly you are having on the community. Building
Forum, whose fellowship pulls talent from relationships takes time, and creating
the private sector to breathe new life into friendships with people at every stage of your
government challenges, or JumpStart Academy career is something you will thank yourself for
Denver, which empowers Denver to connect doing. You can give freely and get to know the
creators with mentors and capital, this city is startup community at the same time. Regular
filled with examples of business and policy startup-scene events like IgniteDenver accept
working together to build a better and smarter volunteers.
community. The Commons on Champa, an
incubator space backed by a public-private Not all that long ago, Denver was a sleepy,
partnership focused on Denver’s downtown tourism-adjacent, oil and gas town. Now, as the
development, is one of the city’s newer spaces city booms, our growing startup community
where many budding entrepreneurs get their can point to a few founders and bridge-
start. builders who invested in the community on the
edge of the Rocky Mountains during the last
three or four decades. That investment in the
next generation lives deep within our Colorado
identity. The real secret sauce in Denver’s
success is individuals that actively embraced
their roles in Denver’s startup ecosystem. From
founders to mentors, people that opt into the
community are faithful to its collective success.
Everyone says it’s not about what you know,
but who you know. Well that may be true, but
in Denver it truly is about the company you
keep.
Alex Kronman, Co-founder and CEO of

flytedesk — Denver, CO, ROTR 5.0, 2016
SALT LAKE CITY
The Secret
Sauce to
Utah’s Startup
Ecosystem
By FRASER NELSON
W
hen I moved to Utah 20 years ago,
my friends on the East and West
Coasts knew the state for one
thing — the greatest snow on earth. What they
and the rest of the country are finally coming
to realize is that Utah offers an entrepreneur’s
playground. My office at Sorenson Impact on
the University of Utah campus is a block from
the Lassonde Entrepreneur Institute, just one of
the reasons the ‘U’ is rated the No. 1 School for
Entrepreneurs by LendEDU.
So what’s making entrepreneurs stick around

after ski season has passed?
Church and State —

Salt Lake City, UT, ROTR 5.0, 2016
1. Healthy Business Environment Rico Brand — Salt Lake City, UT, ROTR 5.0, 2016
The corridor along these mountains, the

Wasatch Front, is known as ‘Silicon Slopes’, and
for a good reason. In article after article, Utah 2. Diversity of Industry
is ranked at the top when it comes to places
Importantly, our startups and our investments
to start a business. A quick scan of Forbes,
are not focused solely on tech. In 2015, 86
Entrepreneur Magazine and others say Utah
of the fastest-growing companies in the US
has a ‘secret sauce’ that includes a young,
were based here. In 2014 and 2015, a total
educated and multilingual workforce, access
of $1.5 billion in venture funding flowed ABOUT THE AUTHOR
to capital, a governor who is passionate about
to Utah companies, much of it from out
cutting regulation and red tape and a triple-A FRASER NELSON is the Director of
of state. We have our share of unicorns —
bond rating. Here is an eyebrow-raising Strategic Partnership at Sorenson
companies with $1 billion+ valuations
statistic: Utah beats New York when it comes Impact. She has spent her career
like Omniture, Pluralsight, Domo, and Inside
to per capita venture capital, second only to in the nonprofit, impact investing,
Sales; and unicorns Ancestry.com, Vivint, and
California and Massachusetts. foundation and government
Qualtrics are literally on the same road.
sectors, with plenty of time skiing
at Alta.
3. Spirit of Generosity The entrepreneurial ecosystem in Utah is
a unique blend of tangibles like supportive
government resources and strong capital
It’s not all about the money, of course. Utah
support from investors like Shark Tank’s
consistently ranks among the highest in
Barbara Corcoran and intangibles like the pay-
the nation for volunteerism. That spirit of
it-forward attitude shared by the community
giving back and paying it forward bolsters
of entrepreneurs and those who support
entrepreneurship. Dozens of incubators exist
them. These factors make it an attractive place
with specific niches and missions, from
investors and entrepreneurs alike, and the
university-based programs like the U’s Lassonde
winters aren’t too bad either.
Center and BYU’s Rollins Center, to Sustainable
Starts Ups and the Salt Mine. Some of these
entities were founded by entrepreneurs as a way
to give back, including Utah Jazz owners Gail
and Larry Miller’s entrepreneurship campus at
Salt Lake Community College, BoomStartUp,
Beehive StartUp, LaunchUp and the Women’s
Tech Council. And Rico Brands’ Jorge Fierro
helps new food ventures, like Argentina’s Best
Empanadas and The Bagel Project, by creating
their products in his kitchen. Impact investing
has a strong foothold in Utah, too. Sorenson
Impact, where I work, has facilitated $100
million in investments in social enterprises
across the globe.
Steve Case at Cotopaxi —

Salt Lake City, UT, ROTR 5.0, 2016
DES MOINES
5 Quick
Tips to Get
Connected
By GEOFF WOOD
D
es Moines has long been known as an
international hub for insurance and
agriculture. Over the past few years we
have seen many local tech startup resources
align within those industries. The Global
Insurance Accelerator has graduated several
classes and is now also the model for a new
AgTech program called the Iowa AgriTech
Accelerator that launched in late 2017. Prairie
Crest Capital and ManchesterStory are two
industry-specific sources of venture capital that
have recently emerged. There is also a broad
base of industry veterans who are willing to
serve as mentors, senior hires and early funders
of local startups.
Des Moines, IA, ROTR 2.0, 2014
A third local startup industry, FinTech, is also
making headlines; several companies in the
space have raised capital (i.e. Dwolla), been
acquired (Banno and Social Money) or gone
public (Workiva). There have also been multiple
recent acquisitions such as Banno and Social
Money and the recent IPO of Workiva.
If you want to break into our vibrant

community, here are five tips for building your
startup in Des Moines:
1. Check out Community Resources

Check out all of the community resources
indexed at StartupDesMoines.com. This
information was assembled by a team of
community leaders to give you the best chance
at being successful in starting a new company
in the area.
2. Subscribe to The Pull

This is a weekly newsletter that highlights the
top stories for the startup community in Iowa.
For more than three years the Gravitate team
has curated the “3 Things to Know” this week ABOUT THE AUTHOR
and shared it with current Iowans, Iowa expats
and the Iowa-curious. GEOFF WOOD is the founder of
Gravitate — the entrepreneurial
center of gravity in downtown Des
Moines — and he has been helping
tell the story of the Iowa startup
Andy Stoll — Des Moines, IA, ROTR 2.0, 2014 community since 2009.
3. Stop by 1 Million Cups
These weekly events happen on Wednesday
mornings. Come to meet others who are
interested in getting started locally. The best
thing about 1 Million Cups is that it happens
every week, so if you can’t make it this
Wednesday, it will be there for you next time.
4. Look into the Iowa Economic

Development Authority
The organization has an array of startup

funding programs. They have funding options
to assist local small businesses from $25,000
to $500,000 with low interest loans or royalty
agreement repayment options.
5. Join the Startup Iowa

community online
Whether you are in Des Moines, Cedar Rapids,

Sioux City or working from a small community
somewhere in between, you can always ask
questions, share experiences or discuss relevant
issues in the Facebook group or on Slack.
Introduction
02
Insight
LEVERAGING DURHAM
Duke I&E Contributes to Durham’s
Growing Entrepreneurial Scene
UNIVERSITY
BALTIMORE
Johns Hopkins’ Role in Bringing the
Benefit of Discovery to the World
RESOURCES
MINNEAPOLIS
University of Minnesota’s Venture Center:
Help Launch 100 Startups in 10 Years
NASHVILLE
The Wond’ry: Innovation on
Campus at Vanderbilt University
MADISON
Innovation Initiative at the
University of Wisconsin–Madison
22 / Rise of the Rest 2018 Ecosystem Playbook / Insight 02: Leveraging University Resources
DURHAM
Duke I&E Contributes to Durham’s

Growing Entrepreneurial Scene
By THE DUKE I&E STAFF
D
uke has always been a leading university Duke I&E is a key supporter of this growth.
for traditional career paths such as pre- Two years after the initiative’s birth, it moved
med and pre-law, but entrepreneurship from Duke’s campus to a space downtown in
didn’t become a primary track for students until the center of the planned 15-acre Durham
a few years ago with the formation of Duke’s Innovation District, a public-private
Innovation & Entrepreneurship Initiative. partnership announced in 2014 to redevelop
The initiative created an entrepreneurial 1 million square feet of space in downtown
hub that pulled together resources offered in Durham into a downtown research hub.
other schools and departments with the goal
of establishing Duke as a leader in university Duke I&E offers resources and programming
innovation and entrepreneurship. for students, including hands-on classes
and a yearlong program that helps students
Similarly, Durham’s economy once relied on become entrepreneurs. But the initiative also
large tech and pharmaceutical companies reaches out to the wider community to foster
located in Research Triangle Park. But within entrepreneurship throughout Durham.
the last several years, the city has seen a
burgeoning entrepreneurial ecosystem, and
startups have become an important part of the
economy.
Adam Klein and Steve Case —

Raleigh-Durham, NC, ROTR 3.0, 2015
1. The Bullpen
The Bullpen is the home of Duke I&E in
downtown Durham. The Bullpen features
classroom, event and meeting space for the
Duke community and Duke I&E’s community
partners.
In an eight-month span, the Bullpen hosted

more than 6,500 visitors, 170 events, and two
classes on entrepreneurship, while more than
over 40 local and non-profit organizations
utilized the space for meetings and events.
Duke I&E also works with other entities that

offer resources, like American Underground.
Duke I&E is a founding partner of American
Underground and has a small office and flexible
work station seating for Duke entrepreneurs in
the @Main location.
Archive Social, pitch competition winner

in Raleigh-Durham, NC — ROTR 3.0, 2015
2. College Night at 4. I&E Academy
American Underground (Innovation & Entrepreneurship)
Duke I&E also partners with American By hosting three to four sessions a
Underground to host College Night, an event semester, I&E Academy focuses on various
during which students from Duke and other topics in innovation and entrepreneurship,
universities can connect with startups housed including protecting intellectual property,
in American Underground. College Night is perfecting a pitch and writing a business plan.
held early in the fall semester so students These sessions are open to students and the
can find internships to complete during the public.
academic year.
5. Start-Up Ventures Clinic

3. StartupConnect Networking Fair The Start-Up Ventures Clinic, an arm of Duke
Duke I&E continues its efforts to help both Law, provides free legal advice to early stage
students and startups throughout the year with companies that haven’t yet raised a significant
the StartupConnect Networking Fair, typically amount of capital.
held during the spring semester. This event
is designed to help students find internships
both with startups both locally and across the 6. Duke Angel Network
nation.
Once companies are ready to raise capital,
ABOUT THE AUTHOR
the Duke Angel Network may be able to help.
The Duke Angel Network invests in Duke- THE DUKE INNOVATION &
affiliated companies both locally and across the ENTREPRENEURSHIP INITIATIVE
nation, pairing expertise of Duke alumni with seeks to make Duke an agent
portfolio companies to support growth. of transformation through an
entrepreneurial spirit, generating
Since its inception in 2015, the Duke Angel
innovations from the ideas that
Network has added 12 companies to its
grow at the University and
portfolio.
translating those innovations
to positively impact individuals,
communities, institutions and
societies.
Even outside the Duke Angel Network,
Durham’s venture capital scene is strong. An
example within the Duke family is Bootstrap
Advisors, founded in 2014 and comprised
of four Duke alumni partners. Bootstrap
Advisors has invested in eight companies,
including Carpe, an antiperspirant lotion
company co-founded by a current Duke
student.
Carpe is now part of Durham’s ecosystem, but

it has roots in Duke I&E and grew through
one of the initiative’s programs. As more
students continue to take advantage of Duke
I&E over the last several years, the university’s
contributions to Durham’s entrepreneurial
ecosystem continue to become more frequent
and robust.
Raleigh-Durham, NC, ROTR 3.0, 2015
BALTIMORE
Johns Hopkins’ Role in

Bringing the Benefits of
Discovery to the World
By CHRISTY WYSKIEL Since 2012, startups based on Johns Hopkins
technologies have raised more than $1.1
F
or more than 140 years, Johns Hopkins billion in follow-on funding, but 85 percent
has brought the benefits of discovery to of that has left Maryland. In 2013, Johns
the world, most notably by pioneering Hopkins Technology Ventures (JHTV), the
breakthroughs that prevent, detect and commercialization arm of the University,
treat disease. This culture of innovation is set out to rewrite this story. We canvassed
a point of pride for our institution, as it has innovation ecosystems across the country to
positively impacted countless lives. Now, we’re understand how they developed startups into
endeavoring to unlock more of our potential sustainable businesses.
in order to revitalize Baltimore’s economy by
focusing on bringing products and technologies The three common resources in each
to market. ecosystem — affordable space, support
services including mentorship, and funding
opportunities — have all been integrated into
the fabric of JHTV’s efforts and have produced
early returns in the development and retention
of job-producing, revenue-generating startups.
These are some of the Hopkins programs that

are contributing to Baltimore’s emergence as
the next great startup destination:
Baltimore, MD, ROTR 4.0, 2015
1. Establish Startup Roots
Entrepreneurship presents challenges that can
derail even the most promising startups. With
three innovation hubs strategically located
across Baltimore, our FastForward program
provides affordable access to 40,000 square feet
of office, co-working and lab space, equipment,
experienced mentors, legal and accounting
services and opportunities to network with
investors. This allows startups to skip time-
consuming searches for office space and
investments in expensive lab equipment, and
to focus on their company’s value drivers.
emocha, a mobile health platform, became

one of the first tenants at our FastForward East
innovation hub because, as CEO Sebastian
Seiguer said, the space, resources and
connections kept the startup competitive. Less
than three years after its inception, emocha has
customers from as close as Baltimore city and
as far as Australia.
Providing high-potential startups like emocha

with the resources and connections they need
to succeed gives them an incentive to set roots
and grow in our city.
Baltimore, MD, ROTR 4.0, 2015
2. Encourage Social Entrepreneurship 3. Empower Students
Not all success is determined solely by numbers Param Shah hasn’t yet completed his junior
on a balance sheet. Many entrepreneurs have year at Johns Hopkins University, but he,
a mission greater than dollars and cents, and through FactoryFour, the company he co-
that’s especially true for social entrepreneurs. founded with recent Johns Hopkins alumnus
Our Social Innovation Lab (SIL) brings Alex Mathews, is poised to revolutionize
change to Baltimore and beyond through the manufacturing. Shah’s team has developed
development of nonprofit and mission-driven middleware that connects 3D scanners and 3D
ventures. printers and points to a future where custom
fabricating products is as viable as mass
While an MBA student at the Johns Hopkins manufacturing.
Carey Business School, J.J. Reidy used the
funding, mentorship, space and valuable Through generous gifts from Johns Hopkins
connections SIL provides to grow Urban alumni, our student startups receive capital
Pastoral, an agricultural development firm that and mentorship to navigate their dorm
aims to revitalize Baltimore through urban room venture into future enterprise. One
farming. It has, as one example, transformed such opportunity is the Ralph O’Connor
shipping containers into vertical farms Undergraduate Entrepreneurship Fund, which
that provide access to fresh foods to people seeds student ventures, introduces them to ABOUT THE AUTHOR
living in Baltimore’s food deserts and create investors and provides mentorship from alumni
jobs in neighborhoods with high rates of entrepreneurs. CHRISTY WYSKIEL is Senior
unemployment. Advisor to the President of Johns
Another opportunity, the JHU Undergraduate Hopkins University on matters
Embedded at the Impact Hub, a socially Summer Entrepreneurship Fund, helped of innovation, commercialization
focused accelerator unaffiliated with Johns Fusiform carry the momentum they built and entrepreneurship. In her role,
Hopkins, SIL gives teams opportunities during the school year through summer break. she heads up Johns Hopkins
to collaborate with, learn from and build This enabled them to develop prototypes, get Technology Ventures, which
connections with like-minded entrepreneurs. their products into clinics and land Shah and includes technology transfer and
Reidy called SIL’s introduction to Baltimore’s Mathews on Forbes’ 30 Under 30 list. the FastForward innovation hub.
social entrepreneurial ecosystem the most Christy is a seasoned entrepreneur
beneficial aspect of the program. and investor with 20 years of
experience primarily focused on
the life sciences and healthcare
industries.
4. Collaboration Cultivates Innovation 5. Looking Forward
The world of business is competitive, but Through investments in traditional and social
creating a culture of innovation benefits from innovation, Johns Hopkins aims to build upon
collaboration. We, like most of the accelerators, its rich history of breakthroughs. Not only
incubators, universities and other organizations does this help people live longer, healthier
focused on entrepreneurship in Maryland, rely lives; it empowers entrepreneurs to better
on others’ strengths. their communities and to change the world.
By making Baltimore a more appealing place
Many of the programs we value and deploy, to seed and sustain a startup, we foresee a
like I-Corps, support entrepreneurs from reimagined Baltimore skyline dotted with the
neighboring universities, and a number of our names of successful, scalable businesses that
startups work out of non-Hopkins innovation were grown right here.
hubs that have resources better suited to their
sector. This cooperative activity provides all our
city’s startups the support they need and helps
revitalize our city, region and state, not just
Johns Hopkins. Baltimore, MD, ROTR 4.0, 2015
MINNEAPOLIS
U of M Venture Center:
Help Launch
100 Startups
in 10 Years
By JOHN STAVIG
M
innesota is a great place to launch a
business. We have an extraordinarily
talented workforce — well educated
and loyal, with a strong work ethic. Historical
investments in public education, environment
and the arts have created a vibrant and
creative community that retains and attracts
talent. We have a supportive and engaged
community that is amongst the leaders in the
nation in volunteering, voting and workforce
participation rates. Startups in healthcare,
retail, enterprise software, data storage,
food and agriculture are at the forefront of
global innovation and connect with a vibrant
corporate community that includes 17 Fortune
500 companies.
Minneapolis, MN, ROTR 2.0, 2014
The University of Minnesota spun out 17
startup companies in 2016 and has helped 1. MN Cup
to launch 100 startups since the Venture
Run by the Carlson School of Management
Center was founded 10 years ago. It is the
at the University of Minnesota, this is the
only university in the country that was
largest statewide new venture competition in
selected to participate in both the National
the country, awarding $450,000 of cash prizes
Science Foundation Innovation Corps and
this year and mobilizing over 400 volunteers
National Institutes of Health REACH programs
in support of Minnesota’s most promising
that provide training and seed funding to
startups. Since 2005, this annual program has
commercialize breakthrough technologies.
supported more than 12,000 entrepreneurs,
The University’s Holmes Center for awarded $2M in seed money to businesses that
Entrepreneurship outreach programs support have gone on to collectively raise more than
emerging entrepreneurs by connecting them $230M.
with resources to develop and grow their
businesses and impactful programs and events
that showcase their entrepreneurial talent and 2. Grow North
emerging businesses:
Grow North is a platform that enables MN
food and agriculture-related startups to grow
their businesses faster. It was born out of
the University of Minnesota’s MN Cup food
and agriculture division, which had over 60
applicants in its first year.
3. Women Entrepreneurs*

Women Entrepreneurs* organizes events to
inspire, connect and support women interested
in building scalable women-led startups in
Minnesota. The platform has 9 founding
organizations, including the University’s MN
Cup.
Deepinder Singh, CEO at 75F, pitch competition
winner in Minneapolis, MN — ROTR 2.0, 2014
Minneapolis, MN, ROTR 2.0, 2014
Other valuable resources have also emerged

throughout the community to support MN 2. Minnestar
entrepreneurs.
Minnestar organizes demo and barcamp events
where hundreds of developers, designers,
1. CleanTech Open Midwest entrepreneurs, investors, and more converge to
learn the latest in the tech world.
The University of St. Thomas organizes
the CleanTech Open’s annual business
accelerator program, which connects 3. Beta.MN ABOUT THE AUTHOR
CleanTech startups with the people and
resources that accelerate their success, and Beta.MN connects entrepreneurs with JOHN STAVIG is the Director of
provide a national platform for public visibility. resources, like future users, investors, the Gary S. Holmes Center for
employees and advisers. They do that by hosting Entrepreneurship at the Carlson
informal events where people have interesting School of Management – University
conversations in comfortable settings. of Minnesota.
4. Impact Hub MSP
Impact Hub MSP is a coworking and event
space for purpose driven professionals.
5. COCO
COCO, a coworking and collaborative space
with locations throughout the Twin Cities, hosts
events and programs to support entrepreneurs.
6. Twin Cities Startup Week

Twin Cities Startup Week annually showcases
the best from the Startup Capital of the North.
Over 70 events throughout the Twin Cities
serve to engage the business community and
highlight the strong progress of local startups.
7. Corporate Support

Minnesota’s robust corporate community has
actively engaged with the startup community.
Target stepped up to host the TechStars Retail
Accelerator; General Mills supported the
launch of Grow North; and Land O’Lakes
has supported a broad range of accelerator
programs.
75F, pitch competition winner in

Minneapolis, MN — ROTR 2.0, 2014
NASHVILLE
The Wond’ry:
Innovation
on Campus
at Vanderbilt
University
By ROBERT GRAJEWSKI
W
ith more cranes in the skyline than
Austin, Denver, San Francisco,
and even New York City and with
nearly 100+ people moving to our city each day,
Nashville is in an era of heightened expansion.
As the city grows and attracts newcomers,
entrepreneurship has flourished alongside it: in
2016 the Kauffman Foundation’s Annual Report
ranked Nashville the #5 hub for startup growth
in the nation.
Nashville, TN, ROTR 1.0, 2014
This growth has not gone unnoticed. Instead,
it has been fully embraced at Vanderbilt
University. In the fall of 2016, Vanderbilt
University launched the Wond’ry, a new
Innovation Center dedicated to creative
collisions on campus. Serving all academic
disciplines of faculty, staff, and students, the
Wond’ry is where new ideas can be generated,
tinkered with, prototyped and tested. With over
30,000+ visitors since its opening, the Wond’ry
is truly creating this creative hub experience.
By providing a physical and social space

where all the necessary ingredients for cross-
disciplinary, multi-disciplinary, and trans-
institutional collaborations can comfortably
linger long enough to find the potent mix, the
Wond’ry is first and foremost a catalyst for
innovative offerings. A complex world presents
wicked problems that defy simple solutions
from within traditional academic disciplines.
We believe the Innovation Center can be the
place where divergent perspectives intersect
to fuel the creative collisions that uncover new
ways through the complexity we face.
At Vanderbilt, our focus is on teaching
innovation, design process, entrepreneurialism, 1. Innovation Garage
and intra-preneurial skills through a hands-
In the Innovation Garage, an array of
on experiential pedagogy, but one aimed at
corporate and non-profit sponsors partner
preparing our participants for future success.
with Vanderbilt student and faculty teams on
We believe that skills like creativity,
cutting-edge research and interdisciplinary
collaboration, empathy, and prototyping
projects. The goal of this program is to identify
interest a wide range of students. Moving
disruptive and innovative solutions that
beyond obvious offerings meant to appeal
improve industry while providing unique
to engineering and business students, we
opportunities for students to build their skills
have found that engaging the departments
through real-world problem solving.
of art, music, drama, English, anthropology,
history, and even the library system allows the
Innovation Center to serve as a true hub for
creative production and innovation on our
2. Entrepreneur PreLaunch
& Entrepreneur PostFlight
campus.
For aspiring Vanderbilt entrepreneurs, the
To help all students engage with
Wond’ry offers an 11-week PreLaunch program
entrepreneurship, the Wond’ry supports four
that provides the foundational knowledge
major pillar programs and averages over 30+
needed to successfully identify and assess
additional workshops a semester, supporting
the potential viability for their venture. In
the entire innovation spectrum. These four
PostFlight, past participants of PreLaunch and/
pillar programs are:
or those entrepreneurs with a more developed
endeavor learn all the necessary steps needed
to successfully launch a quality venture from
our industry experts and mentors.
ABOUT THE AUTHOR
ROBERT GRAJEWSKI is the Evans

Family Executive Director of the
Wond’ry at Vanderbilt University
3. Social Entrepreneurship & Ventures
The Social Entrepreneurship Program is an
important platform for students to work
together to tackle important societal problems
like affordable housing, transportation and
health that have the potential to be adopted
into full-scale programs and potential
partnerships with non-profit and government
organizations.
4. Fostering an Innovation Culture

From artist/music exhibits and speaker series
to hackathons and business plan competitions,
the Wond’ry hosts workshops, speakers
and events that cater to an innovative and
entrepreneurial spirit.
MADISON
Innovation
Initiative at
the University
of Wisconsin–
Madison
By AARON OLVER
Y
ou do not have to live near an ocean
to take the plunge into innovation and
entrepreneurship. While eight of the ten
U.S. universities conducting over $1 billion of
R&D each year are in states bordering an ocean,
two of the nation’s research powerhouses —
the University of Wisconsin–Madison and
University of Michigan — are inland.
Madison, WI, ROTR 2.0, 2014
The University of Wisconsin–Madison has
been focused on making research useful to the 1. Discovery to Product
world at least since 1925. In that year, a group
Discovery to Product is a commercialization
of visionaries came together to patent a UW
program that helps campus innovators plan,
invention that promised to virtually eliminate
develop, commercially de-risk and nurture
rickets and created the oldest university
early stage projects that could become startups
technology transfer organization in the country,
or licensable technology.
the Wisconsin Alumni Research Foundation,
or WARF.
Today, the University of Wisconsin–Madison, 2. @1403

WARF, and University Research Park work
@1403 is a campus-focused co-working
together to build a world-class startup
and innovation hub on campus. It’s home
environment here in Madison. Collectively,
to Discovery to Product, the UW Law
we support a number of innovation initiatives
& Entrepreneurship clinic, Madworks
including:
Coworking @1403, and a number of business-
focused student organizations. Madison, WI, ROTR 2.0, 2014
3. MERLIN Mentors And more and more, we’re working to
nurture a cluster of regenerative medicine
companies. Cellular Dynamics International (a
MERLIN Mentors aims to create a larger pool
Fujifilm company), a global leader in induced
of viable entrepreneurs by matching new
pluripotent stem cells therapies, grew out
entrepreneurs with experienced mentors drawn
of ground-breaking research from Professor
from Madison’s business community.
Jamie Thomson’s lab. Stratatech, a regenerative
medicine company revolutionizing the
4. Entrepreneurons treatment of burns and wounds with their skin

substitute, grew out of the unexpected results of
Entrepreneurons is a free seminar and basic research in another UW lab.
networking session on a variety of topics related
Madison isn’t just about life science, though.
to innovation and entrepreneurship and held
In 1979, a UW computer science grad named
at the Wisconsin Institutues for Discovery (next
Judy Faulkner started a healthcare IT firm here
door to @1403).
called Epic Systems. Today, Epic employs 10,000
people in the Madison area and will host half
5. WARF Accelerator of the nation’s medical records. With the talent

graduating from the university or emigrating
WARF Accelerator complements Discovery to from Epic, Madison is seeing an explosion
Product by helping UW inventors develop their of software and health IT startups. Last year,
technologies scientifically and position them area startups raised over $114 million and
for commercial success with expert advice from helped make Madison the top city in the
a team of mentors, known as Catalysts. Midwest for venture capital investment
per capita. Accelerators like Gener8tor and
Once companies launch, it’s our mission at coworking hubs like 100State and Starting
the University Research Park to help these Block are popping up to fuel the trend.
technology companies gain their footing and ABOUT THE AUTHOR
scale. With life science and engineering research
AARON OLVER is Managing
rolling on campus, and health IT making
Director of University Research
Madison the second most concentrated
Park and a former Wisconsin
place in the country for software, Madison is
Secretary of Commerce.
positioned to become a HealthTech Capitol. We
may not have saltwater, but we’ve got an ocean The views expressed in this article
of opportunity. are solely those of the author.
Introduction
03
Insight
FOSTERING
NASHVILLE
Tennessee Proactively
Pursues Startup-Friendly Status
INNOVATION
CHARLESTON
WITH Public Support for Entrepreneurs
BUFFALO
PUBLIC POLICIES
Public Support in the
City of Good Neighbors
+ PROGRAMS
42 / Rise of the Rest 2018 Ecosystem Playbook / Insight 03: Fostering Innovation with Public Policies + Programs
NASHVILLE
Tennessee Proactively Pursues

Startup-Friendly Status
By CHARLIE BROCK
1. Incubators & Accelerators
T
ennessee is gaining national awareness
as a startup-friendly state. In a region In addition to all-time highs in capital
that excels in the traditional industries investment, founders have a host of incubation
of healthcare, logistics, agriculture and resources. Launch Tennessee, for example,
manufacturing, entrepreneurs are innovating is a public/private partnership that fosters
in exciting ways by leveraging new angel and entrepreneurship. It operates six geographically
venture funds, growth resources and founder- distributed Entrepreneur Centers which
friendly public policy. There’s never been a exemplify a unique state-sponsored model that
better time to be an entrepreneur in Tennessee. offers direct-to-founder growth support. The
state is home to industry-specific accelerators,
Venture funding in the state grew 16% in the such as EPIcenter and Dynamo for
last three years, from $368M in 2014 to $428M logistics, GigTank for high-bandwidth
in 2016 according to Pitchbook and SEC filings, applications, Project Healthcare and Project
outpacing the 0.29% national growth in venture Music. In addition, diversity-focused programs
investment. Further bucking national trends, target underserved populations, such as Bunker
Tennessee avoided a decline in venture activity Labs for veterans, Propel for minority founders
in 2016 thanks to a healthy startup ecosystem. and CO.STARTERS for rural entrepreneurs.
These trends validate the strength and flow of These high-impact additions to Launch
capital ready to support new businesses. Tennessee’s accelerator network help both
early-stage and growth-stage businesses
develop.
2. Incentives & Public Policies
Founder-friendly public policies also make
Tennessee attractive for new business growth.
In fact, Launch Tennessee advocates for
policies that directly affect entrepreneurs,
such as the 2016 passage of an Angel Tax
Credit incentivizing angels to invest in pre-
traction startups. In 2017, over $1.5 million
of tax credits were redeemed, yielding over
$5M of angel investment, with 30% of the
participants representing new angel investors.
A total of $4M is available for Launch Tennessee
to distribute to qualified angels investing
in pre-qualified companies. In 2017, the
Tennessee legislature passed a Small Business
Innovation Research (SBIR) matching fund and
the program was met with great enthusiasm
and success in the market. Launch Tennessee
will be advocating for renewal and expansion of
the program in 2018, along with other startup-
friendly policies.
Tennessee is among nine states in the country

with no state income tax. This is crucial for
sustainable growth: U.S. Census Bureau data
show that these nine states enjoyed a 9.1%
growth in population over the last five years,
whereas the 41 with a state income tax grew
only 3.5%.
ABOUT THE AUTHOR
CHARLIE BROCK is the CEO

of Launch Tennessee, a public-
These unique-to-Tennessee attributes,
3. Technology Infrastructure paired with higher quality of life (Nashville is
private partnership focused
on the development of high-
consistently ranked among the best places to growth startups across the
High-speed fiber internet offers another live in the U.S. for millennials) and lower cost of state. By working in the areas of
business edge. Chattanooga, aka the “Gig City,” living relative to more mature ecosystems make entrepreneurship, capital formation,
was the nation’s first municipality to build a Tennessee an ideal location to start and grow a commercialization and outreach,
fiber internet delivering multiple gigabits of business. Young entrepreneurs and established Launch Tennessee works to help
connectivity; it’s now the country’s fastest, firms alike have recently opened second homes make TN one of the best states in
offering 10G/sec. Chattanooga’s success in Tennessee. the country for growing successful
inspired other Tennessee public utilities and
startups.
municipalities to build similar programs.
CHARLESTON
Public
Support for
Entrepreneurs
By AMY LIVINGSTON
F
rom meetups geared for Women in
Tech, to pitch events at the College of
Charleston, there are many good reasons
why the Charleston area has been dubbed the
“Silicon Harbor” and was ranked the #7 metro
nationally for Economic Growth Potential in
2016. The community continues to experience
tremendous high-tech GDP growth, as local
government works to play a supporting role.
Across the famed Arthur Ravenel Jr. Bridge

and along the Charleston Harbor, is Mount
Pleasant, SC, the entrepreneur-friendly town in
Charleston County. Here, the fastest-growing
city east of the Mississippi River focuses on
supporting the innovation economy and
entrepreneurs throughout their lifecycle in
three ways: public-private partnerships, events
and incentives.
Charleston, SC, ROTR 3.0, 2015
1. Public-Private Partnerships
Early-stage entrepreneurs will find the Harbor
Entrepreneur Center’s accelerator program
of interest — a twelve-week, fully immersive
program designed to help the entrepreneur
build a scalable business. In this program,
successful entrepreneurs serve as mentors
and introduce high-impact business concepts
through an intense curriculum. At the end of
the program, startups know what is needed
to take the next step and are introduced
to possible capital sources to help them
grow. This accelerator program is a product
of a Town-sponsored incubator and remains
a public-private partnership. The Harbor
Entrepreneur Center provides additional
offerings for entrepreneurs at all levels to
include Forum mastermind groups, networking
events, retreats and more.
Charleston, SC, ROTR 3.0, 2015
2. Events Another example is the annual DIG SOUTH
Interactive Conference, which is sponsored by
the Town of Mount Pleasant. The conference
Mount Pleasant also sponsors a variety of
connects the South’s top tech and creative
events to help catalyze connection, education
talent to leading global brands and fast-
and support for entrepreneurs. Through an
growing startups. Now in its fifth year, the DIG
innovative public-private partnership the
Innovation Conference (ICON) is where leading
Town hosted Coworking Day Mount Pleasant,
brands such as Vox Media, Facebook, Buzzfeed,
the region’s largest coworking initiative, which
CNN and Boeing meet the smartest, most
attracted nearly 250 entrepreneurs who also
scalable startups. Leading up to the big event
helped donate over 500 pounds of food to a
each year, the Town also partners with the DIG
local nonprofit.
SOUTH team to host mashups featuring local
entrepreneurs.
3. Incentives
Designed to attract and retain area
entrepreneurs and their growing companies,
Mount Pleasant is one of only a few
municipalities in South Carolina offering
its own incentives package. The Economic
Development Incentive Grant program provides
for selective investment in companies that
substantially add to the tax base, create clean,
high-paying jobs, and are compatible with the
built and natural environment of the town.
Grants for qualifying businesses are available
to reimburse for all or part of business license
taxes, municipal impact fees and more.
ABOUT THE AUTHOR
AMY LIVINGSTON is the Business

& Tourism Manager for the Town of
Charleston, SC, ROTR 3.0, 2015 Mount Pleasant, SC.
BUFFALO
Public
Support in the
City of Good
Neighbors
By DR. MARNIE LAVIGNE
B
uffalo, NY is more than snow, postseason
droughts, and chicken wings these days.
In 2016 Buffalo was featured as one of
eight cities on Katie Couric’s Cities Rising series,
and more recently as one of three cities on
Inc.’s Unexpected Places That Are Actually
Amazing for Startups. Buffalo’s comeback has
come from the multi-billion dollar public-
private investments in its infrastructure and
innovation economy and a long-awaited
reversal of loss of population, especially among
young adults.
Buffalo, NY, ROTR 4.0, 2015
In addition to physical transformation through The City of Good Neighbors has created
construction projects throughout the city a new community for startups and
from the Buffalo Niagara Medical Campus to entrepreneurs. Here are three types of support
Canalside and Solar City, Western New York has for entrepreneurs that is being driven by public
jumped on entrepreneurship as the catalyst for policy and programming.
creating a new economy through its abundant
innovation assets, including nearly two dozen
higher education institutions, that has yielded 1. Resources & Mentoring
explosive growth in its startup scene in IT,
advanced manufacturing, life sciences, and Once on their own, today’s entrepreneurs can
consumer products and services. choose among hundreds of resources through
an online directory at Launch NY. Public-
private funding has driven growth of
tailored support, such as at launchny.org, a
nonprofit venture development organization
ABOUT THE AUTHOR
supported through federal funding and private
philanthropy to deliver pro bono mentoring DR. MARNIE LAVIGNE has spent
and hard-to-find seed capital to high-growth more than 25 years in both the
potential businesses. In addition to running the private and public sectors creating
most active seed fund in the region supporting new products and start-up
the entire western half of the state, Launch NY businesses, driving innovation and
serves more than 650 high-growth startups economic growth in high-tech
through its local entrepreneurs-in-residence industries, such as life sciences,
who provide tailored, one-on-one coaching, informatics and advanced
combined with access to specialized expertise manufacturing. Her passion for
through its National Mentor Network of 2000 working with start-ups took root
advisors. Other publicly-funded mentorship from her experience launching
programs listed in the Resource Network range health informatics businesses
from Small Business Development Centers with colleagues in the 1990’s as
to programs serving industry sectors such as she finished her doctoral work
cleantech through the New York State Energy at the University of Rochester,
Research Development Agency. which resulted in growing two
different firms with more than 100
employees and two initial public
Steve Case in Buffalo, NY, ROTR 4.0, 2015 offerings (IPOs).
2. Incubator Facilities
Public funding has also supported incubator
facilities and their programs in thriving
downtown areas such as the Buffalo Niagara
Medical Campus (BNMC.org), home to more
than 100 businesses in healthcare and beyond.
The Innovation Center at BNMC is a must see
for visitors to experience the buzz at dig, the
region’s premier coworking and event space
for entrepreneurs, and Z80 Labs, an internet
startup incubator founded by SoftBank Capital
partners providing space and seed capital. The
BNMC also houses a new crop of business plan
competition winners annually from the world
class startup competition fueled by New York
State’s “Buffalo Billion”, known as 43North,
whose winners of $5 million in prizes receive
a free year of incubator space and support
programming. The $1 million grand prize
winner in 2015, ACV Auctions, has brought
more that $21 million in private funding to
Buffalo and has grown to over 160 employees.
Steve Case in Buffalo, NY, ROTR 4.0, 2015
3. Tax Incentives
The startup experience in Buffalo is topped
off by a tax incentive program, START-UP NY,
that has caught national attention through
its dynamic TV commercials. Since Buffalo
has become the most active region for the
program in New York State by welcoming more
than 80 companies to receive 10 years free of
corporate taxes — and personal income taxes
for employees — virtually every entrepreneur
is attracted to connect with the colleges and
universities who sponsor startups who tap
these tax benefits and an array of facilities,
talent, and other resources.
The innovation and excitement that

entrepreneurs bring to any city is a cornerstone
of Buffalo’s comeback. As the private sector
steps up to match the public sector support for
the ecosystem, startup successes will emerge at
an unprecedented rate in the region’s history.
Steve Case in Buffalo, NY, ROTR 4.0, 2015
Introduction
04
Insight
PROMOTING
CINCINNATI
The Brandery & Big Companies:
How Cincinnati Fosters
Partnerships that Work
PARTNERSHIPS FROM ATLANTA

Engage:
10 BigCos Back Atlanta-Based
REGIONAL CORPORATIONS
Accelerator & Venture Fund
DES MOINES
+ LOCAL INDUSTRY Iowa Accelerators Focus

on AgTech and Insurance
53 / Rise of the Rest 2018 Ecosystem Playbook / Insight 04: Promoting Partnerships from Regional Corporations + Local Industry
CINCINNATI
The Brandery
& Big Companies:
How Cincinnati
Fosters
Partnerships
That Work
By ROB MCDONALD
W
hen we launched The Brandery in
2010, we knew we had to play to the
strengths of Cincinnati. This meant
leveraging the Fortune 500s (or BigCos) and
the incredible design and creative community
that serves them. The C-suite at the BigCos
were eager to write us meaningful sponsorship
checks and helped us welcome our companies
to town by hosting them at ball games and
other social activities.
Cincinnati, OH, ROTR 1.0, 2014
In return, the BigCos employees interacted with
The Brandery’s talented team, learning about 1. Capital
“innovation” and “startup culture.” There’s
Many BigCos have existing venture groups
no doubt we both added a bit of value to one
with access to plenty of capital, but they can
another, but it didn’t really move the needle for
often lack clear directive for those investments.
the startups.
Conversely, startups are always on the hunt for
What did move the needle was developing capital and have developed a vast network of
meaningful, collaborative relationships with expertise in this area from the VCs and angels
the BigCos. Fostering these relationships with that support them. By connecting BigCos with
BigCos not only helped The Brandery, but also your network, we can serve your ecosystem and
enriched the startup ecosystem in Cincinnati. the BigCos’ investment strategy.
Here was our approach:
2. Mentorship
Nothing fosters a collaborative relationship
like mentors. Developing C-suite mentors can
create powerful champions for your startup.
These relationships take time to identify and
form, but the investment is time well-spent for
cultivating a startup-friendly ecosystem in your ABOUT THE AUTHOR
community.
ROB MCDONALD is the
Co‑founder of the Brandery,
a top‑10 ranked seed stage
accelerator in Cincinnati, OH. In
addition, Rob co-manages Vine
Street Ventures, a micro venture
fund, and is a partner in the
business and finance group of Taft
Stettinius and Hollister. Civically,
Rob serves on the Boards of the
Cincinnati Symphony Orchestra
Steve Case and former U.S. Secretary of Commerce and Dan Beard Council (Cincinnati’s
Penny Pritzker — Cincinnati, OH, ROTR 1.0, 2014 Boy Scout’s Council).
3. Pilots & Commercial Opportunities
As your relationships with BigCos begin to
grow, partner with these firms in pilot programs
so they can see how your startup can really add
value. After a successful pilot, convert these
BigCos into paying customers. They will benefit
from your expertise while you see growing
revenue numbers and impressive additions to
your clientele list.
4. M&A
Think acquisition from a BigCo could be in
your future? Successful exits can take startup
ecosystems to the next level. In addition to
adding potentially immense value to the BigCo
that acquires them, the creation of wealth
within the startup inevitably trickles back into
the ecosystem from a new angel or the next
generation of self-funded founders.
Startups aren’t the only ones who can create an

entrepreneurial ecosystem for your community.
BigCos can provide incredible value as well;
so give them a seat at the table. A healthy
relationship will make everyone prosper.
Cincinnati, OH, ROTR 1.0, 2014
ATLANTA
Engage:
10 BigCos
Back Atlanta-
Based
Accelerator &
Venture Fund
By BLAKE PATTON
S
itting in a conference room overlooking
the city skyline of Atlanta, Invesco
CEO Marty Flanagan and Georgia Tech
President Bud Peterson shared that leaders of
the city’s largest companies wanted to unite
the region’s global companies and the thriving
startup ecosystem.
Atlanta, GA, ROTR 3.0, 2015
Marty talked about his time in Silicon Valley The CEOs and innovation executives of these
and how leaders of the technology community companies were thinking big and ready
and the large companies were more connected, to put “skin in the game.” That led to the
and how that fostered the Valley’s innovation launch of Engage, a new mentorship-driven
ecosystem. accelerator and venture fund in partnership
with 10 global companies, Georgia Tech
Bud talked about the more than 15 corporate and Tech Square Ventures.
innovation centers that have opened in Georgia
Tech’s Tech Square including AT&T, Delta, Engage will be based at Georgia
Home Depot, and Southern Company — Tech’s Advanced Technology Development ABOUT THE AUTHOR
and how they were looking to tap into the Center in Tech Square and is open to startups
innovation happening in the region. across the country, with a focus on go-to- BLAKE PATTON is the Managing
market strategy and customer access. The Partner of Tech Square Ventures,
participating companies include AT&T, a seed and early stage venture
Chick-fil-A, Cox Enterprises, Delta Air Lines, firm based in Atlanta, Georgia.
Georgia-Pacific, Georgia Power Foundation, He’s a serial entrepreneur, investor
Partpic, pitch competition winner Intercontinental Exchange (ICE), Invesco, The and leader in the Atlanta startup
in Atlanta, GA — ROTR 3.0, 2015 Home Depot, and UPS. community.
The companies have committed $16.5 million But what startups need more than anything else
in capital to the fund to date and the CEOs is market access and customers. For startups
of the founding companies will serve on looking to bring new innovations to market,
the Engage Board of Directors. In addition, Atlanta is the place to be.
executives from the companies will serve
as mentors for startups participating in the Engage highlights the best of Atlanta: it
accelerator. brings together a group of forward-thinking
global companies and a world class research
What makes Engage unique is the interaction university with the vision and dedication to
of these global companies with the startup drive innovation and provide entrepreneurs
ecosystem to help entrepreneurs build access to markets, customers and funding.
companies that will transform their markets.
Rather than filling the specific needs of a single
large company, Engage startups will benefit
from the combined perspective of the founding
companies.
Atlanta already enjoys many of the key

ingredients for a successful startup ecosystem
with a top 10 pool of tech talent, world
class research universities including the
nation’s largest and most diverse engineering
university in Georgia Tech, a growing base of
active entrepreneurs and investors, as well as
incubators and clusters of startup activity like
the Advanced Technology Development Center,
Atlanta Technology Village, Switchyards and
many others.
Atlanta, GA, ROTR 3.0, 2015
DES MOINES
Iowa
Accelerators
Focus on
AgTech and
Insurance
By TINA HOFFMAN
S
purred by local business and community
leaders, specialized startup accelerators
are forming across Iowa to capitalize on
the specific strengths of the regions they serve.
For example, Des Moines is home to the

headquarters of Allied Insurance and the
Principal Financial Group Inc., and a significant
location for Wells Fargo Home Mortgage. The
area has one of the highest concentrations of
finance and insurance-related employment in
the country.
In addition, 40 miles north of Des Moines
in Ames is Iowa State University, a major 1. The Rise of Insurance-Tech
agricultural R&D center. With these assets
In February, Des Moines fintech startup Dwolla
in place, much of the tech startup activity in
announced a new $6.8 million investment
central Iowa is focused on creating innovation
round. The company has already raised $35
in finance, insurance and agriculture.
million from investors throughout the country,
including actor, investor and Iowa-native
Ashton Kutcher.
After witnessing the success of Dwolla and ABOUT THE AUTHOR

other fintech companies, and anticipating
similar activity in the insurance industry, TINA HOFFMAN was the marketing
several local insurance companies pooled and communications director for
resources in Des Moines to form the the Iowa Economic Development
nation’s first insurance technology — or when this insight was first
Des Moines, IA, ROTR 2.0, 2014 insurtech — accelerator. published.
In its third year, the six-company current cohort
of the Global Insurance Accelerator in Des 2. The Rise of AgTech
Moines hails from Belgrade, Boston, Detroit,
Iowa produces more corn, eggs, pork and
Munich, Toronto and Tucson. The accelerator
soybeans than any state, and now the state is
is giving Des Moines insurance leaders greater
also making a play to be the center of AgTech.
access to the technology that could change the
industry. The American Farm Bureau Federation has held
an agriculture startup competition for three
Grinnell Mutual Reinsurance Company is one
years, and teams from Iowa have won it twice.
prime example. Grinnell Mutual is a 100-year
Both winning teams featured alumni from Iowa
old company headquartered in Grinnell, Iowa,
State University’s College of Agriculture and Life
a town of less than 10,000 people. In 2016,
Sciences, who also participated in the college’s
Grinnell Mutual led investments in seed-stage
Agricultural Entrepreneurship Initiative
financing rounds for two insurance technology
program.
startups: one which analyzes truck driver
performance, and one which helps insurance With this national leadership established, in
agents more effectively market themselves 2016, two new AgTech accelerators announced
online. Grinnell Mutual plans to deploy the they were forming in central Iowa. One will be
startups’ technologies in its own business, and headquartered in Des Moines, and its sponsors
believes the technologies have potential for include DuPont Pioneer and John Deere. Iowa
further adoption in the insurance industry. State University is organizing the other in Ames,
and its sponsors include a number of local
agriculture companies.
3. Strategic Planning for the Future
In central Iowa, there’s ongoing collaboration
between entrepreneurs, community leaders
and the local business community to take
the steps necessary to foster a sustainable
innovation economy. Places like Gravitate,
an incubator with locations in Des Moines
and Ames, are celebrated and encouraged.
The region is aware of its strengths and taking
measured, planned steps to build on from
them.
Find out more about how Iowa fosters

the development of startups at www.
iowaeconomicdevelopment.com/business.

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RISE OF THE REST

POWERED BY @RiseOfRest www.revolution.com/rotr

INSIGHT 01 INSIGHT 02 INSIGHT 03 INSIGHT 04

1 / Rise of the Rest 2018 Ecosystem Playbook

2 / Rise of the Rest 2018 Ecosystem Playbook / Introduction

To help answer those questions, we have compiled the insights,

3 / Rise of the Rest 2018 Ecosystem Playbook / Introduction

4 / Rise of the Rest 2018 Ecosystem Playbook / Introduction

Minneapolis, MN Ann Arbor, MI

Salt Lake City/Provo, UT Lincoln/Omaha, NE Pittsburgh, Baltimore, MD

5 / Rise of the Rest 2018 Ecosystem Playbook / Introduction

CONVENING YOUR DENVER

The PHX Startup Ecosystem:

As part of the #yesphx mission, we also want to

Local Motors — Phoenix, AZ, ROTR 5.0, 2016

Visit the Arizona Commerce Authority’s

RAOUL ENCINAS, Founder of PhosLabs

The cornerstone of the #yesphx community

WebPT — Phoenix, AZ, ROTR 5.0, 2016

ZACH FERRES, CEO of Coplex

Becoming an active, contributing, respected

And now that you’re home, help make it a better

Tuft & Needle — Phoenix, AZ, ROTR 5.0, 2016

City Hall — Denver, CO, ROTR 5.0, 2016

Alex Kronman, Co-founder and CEO of

So what’s making entrepreneurs stick around

Church and State —

The corridor along these mountains, the

Steve Case at Cotopaxi —

Des Moines, IA, ROTR 2.0, 2014

If you want to break into our vibrant

1. Check out Community Resources

2. Subscribe to The Pull

4. Look into the Iowa Economic

The organization has an array of startup

5. Join the Startup Iowa

Whether you are in Des Moines, Cedar Rapids,

Des Moines, IA, ROTR 2.0, 2014

Duke I&E Contributes to Durham’s

Adam Klein and Steve Case —

In an eight-month span, the Bullpen hosted

Duke I&E also works with other entities that

Archive Social, pitch competition winner

5. Start-Up Ventures Clinic

Carpe is now part of Durham’s ecosystem, but

Raleigh-Durham, NC, ROTR 3.0, 2015

Johns Hopkins’ Role in

These are some of the Hopkins programs that

Baltimore, MD, ROTR 4.0, 2015

emocha, a mobile health platform, became

Providing high-potential startups like emocha

Baltimore, MD, ROTR 4.0, 2015

Minneapolis, MN, ROTR 2.0, 2014

3. Women Entrepreneurs*

Other valuable resources have also emerged

6. Twin Cities Startup Week

7. Corporate Support

75F, pitch competition winner in

Nashville, TN, ROTR 1.0, 2014