NAME: BINWAG, ALVINCENT D.

SECTION: BSN 2A-A

CLINICAL INSTRUCTOR: SIR VENICIO G. GUILLAO

DRUG NAME MECHANISM OF ACTION INDICATION / CONTRAINDICATION ADVERSE EFFECT NURSING RESPONSIBILITIES

GENERIC: Gentamicin interferes with bacterial INDICATION: CNS: Acute organic mental BEFORE:
protein synthesis by binding to 30S Treatment of serious bacterial infections syndrome, confusion, depression, Dx:
Gentamicin ribosomal subunits resulting in a caused by aerobic gram-negative fever, headache, increase a. Check for Doctors order
defective bacterial cell membrane. organisms and some gram-positive protein in cerebrospinal fluid, b. Check for the history of allergies.
BRAND: organisms including Citrobacter lethargy, myasthenia, gravis-like Tx:
SOURCE: species, Enterobacter species, E. coli, syndrome, neurotoxicity,
Gentamicin Klebsiella species, Proteus species, peripheral neuropathy, or a. Restrict amount of drug available
Team, C. by Mimso. (n.d.). Pseudomonas aeruginosa, encephalopathy. to patient.
CLASS: Gentamicin: Indication, Dosage, Side Staphylococcus Epidermidis. CV: Hypertension, hypotension, b. Periodically assess dose.
AMINOGLYCOSIDE Effect, Precaution | MIMS Philippines. palpitations. c. Perform a thorough physical
ANTIBIOTICS Www.mims.com. CONTRAINDICATION: EENT: Blurred vision, increased assessment to establish baseline
https://www.mims.com/philippines/dr salivation, laryngeal edema, data before drug therapy begins,
Antibiotic Drug ug/info/gentamicin?mtype=generic Contraindicated to patients with ototoxicity, stomatitis, vision to determine the effectiveness of
hypersensitivity or serious toxic reaction changes. therapy, and to evaluate for the
PHARMACOLOGIC: to other aminoglycosides, GI: Anorexia, nausea, occurrence of any adverse
hypersensitivity to gentamicin or its splenomegaly, transient, effects associated with drug
Bactericidal and is a components. hepatomegaly, vomiting therapy.
broad spectrum of GU: Nephrotoxicity
antibiotic HEME: Anemia, eosinophilia,
leukopenia, increased or EDx:
DOSAGE: decreased reticulocyte count,
granulocytopenia. a. Educate mother on drug therapy
10 mg OD MS: Arthralgia, leg cramps to promote compliance.
RESP: Pulmonary fibrosis, b. Ensure that medication given
ROUTE: respiratory depression. intravenously will show no signs of
IV SKIN: Alopecia, generalized adverse effects to patient.
burning sensation, pruritus,
purpura, rash. DURING:
OTHER: Anaphylaxis, injection site Dx:
pain, superinfection, weight loss. a. Check for Doctor’s order.
b. Check for drug or food
interactions.
c. Monitor patient for
superinfection. If it occurs, expect
to discontinue drug and provide
treatment as ordered.
Tx:
a. Administer right dosage of
medication.
EDx:
a. Instruct mother to verbalize
concern when unnecessary
reactions occur.
AFTER:
Dx:
a. Assess knowledge/teach patient
appropriate use ,interventions to
reduce side effects, and adverse
symptoms to report
b. Assess for clinical improvement.
Tx:
a. Provide rest and comfort.
EDx:
a. Monitor patient compliance to
drug therapy.
d. Instruct patient to verbalize
feelings and concerns.
 DRUG NAME MECHANISM OF ACTION INDICATION / CONTRAINDICATION ADVERSE EFFECT NURSING RESPONSIBILITIES

GENERIC: Clindamycin inhibits bacterial INDICATIONs: CNS: BEFORE:

protein synthesis by binding to 23S Clindamycin is indicated for the Dizziness, headache, Dx:
Clindamycin RNA of the 50S subunit of the treatment of serious infections vertigo. a. Check for Doctors order
bacterial ribosome. It impedes caused by susceptible anaerobic b. Check for allergy reactions
BRAND: both the assembly of the ribosome bacteria, as well as susceptible CV:
and the translation process. The staphylococci, streptococci, and Arrhythmias, hypotension. Tx:
Clindacin molecular mechanism through pneumococci. GI:
which this occurs is thought to be Pseudomembranous a. Periodically assess dose.
due to clindamycin's three- CONTRAINDICATION: colitis, diarrhea, bitter b. Perform a thorough physical assessment
CLASS: dimensional structure, which Clindamycin is contraindicated in taste, nausea, vomiting. to establish baseline data before drug
THERAPEUTIC closely resembles the 3'-ends of L- patients who have had an allergic SKIN: therapy begins, to determine the
Lincomycin antibiotics Pro-Met-tRNA and deacylated- reaction to it, and it should be used Rashes effectiveness of therapy, and to evaluate
tRNA during the peptide with caution in those who have a for the occurrence of any adverse
PHARMACOLOGIC: elongation cycle - in acting as a history of regional enteritis, effects associated with drug therapy.
structural analog of these tRNA ulcerative colitis, or antibiotic-
Nonsteroidal molecules, clindamycin impairs associated colitis.
cyclooxygenase-2(COX-2) peptide chain initiation and may EDx:
inhibitor stimulate dissociation of peptidyl- a. Instruct mother to recognize and
tRNA from bacterial ribosomes. immediately report adverse drug effects
DOSAGE:
SOURCE: DURING:
0.07 ml TID Clindamycin. (n.d.). Dx:
Go.drugbank.com. a. Check for Doctor’s order.
ROUTE: https://go.drugbank.com/drugs/D b. Check for drug contraindications
B01190
IV Tx:
a. Administer right dosage of medication.
EDx:

a. Remind to check the heplock site for

swelling or redness.

AFTER:
Dx:

a. Assess knowledge/teach mother some

interventions to reduce side effects, and
adverse symptoms to report
 b. Assess for clinical improvement, record
onset of relief.

Tx:
a. Monitor patient’s other signs and
symptoms.
EDx:
a. Instruct mother to verbalize feelings and
concerns.
b. Encourage mother to recognize and
immediately report adverse drug effects.
 DRUG NAME MECHANISM OF ACTION INDICATION / ADVERSE EFFECT NURSING RESPONSIBILITIES
CONTRAINDICATION

GENERIC: Antagonizes histamine’s INDICATION: CNS: dizziness, drowsiness, BEFORE:

effects at histamine1-receptor Allergic symptoms are caused fatigue Dx:
Cetirizine sites, preventing allergic by histamine release. a. Check for Doctors order
response. CV: palpitations, edema b. Check for hypersensitivity.
BRAND: CONTRAINDICATION: Tx:
Medrizine SOURCE: a. Perform a thorough physical assessment to
Schull P., (2013). McGraw-Hil Contraindicated to patients EENT: pharyngitis establish baseline data before drug
CLASS: Nurse’s Drug Handbook that are hypersensitive to the therapy begins, to determine the
Seventh Edition. LLC, McGraw- drug or hydroxyzine. It is also effectiveness of therapy, and to evaluate
THERAPEUTIC Hill Education. contraindicated to patients GI: nausea, vomiting, for the occurrence of any adverse effects
Anti-histamine with acute asthma attacks, abdominal dis- tress, dry mouth associated with drug therapy.
angle-closure glaucoma, b. Restrict amount of drug available to
PHARMACOLOGIC: pyloroduodenal obstruction, patient.
and breastfeeding. Musculoskeletal: myalgia, joint c. Periodically assess dose.
DOSAGE: pain EDx:
0.25 ml BID
a. Educate the mother on drug therapy to
Respiratory: bronchospasm
ROUTE: promote compliance.
Oral b. Ensure the patient takes the medication as
prescribed.
Skin: photosensitivity, rash,
c. Instruct mother to observe aseptic
angioedema
technique before administering oral
medication.
Other: fever
DURING:
Dx:
a. Check for Doctor’s order.
b. Monitor for adverse effects.
c. Check for drug to drug
Interactions
Assess overgrowth of infection

Tx:
a. Assist mother in administering cetirizine
drops orally.
b. Demonstrate correct dosage and route of
cetirizine drops.
c. Give more time to administer medication.
EDx:
a. Inform of drugs and food that can interact
b. Instruct mother to verbalize feelings and
concerns.
c. Instruct mother to recheck the dosage of
the medicine drop to maintain correct
dosage.

AFTER:
Dx:

a. Assess knowledge/teach patient

appropriate use ,interventions to reduce
side effects, and adverse symptoms to
report
b. Monitor for effectiveness as exhibited by a
decrease in symptoms
c. Monitor for side effects.
Tx:
a. Monitor for any signs of bleeding
b. Monitor any adverse effect.
EDx:
a. Instruct patient to verbalize feelings and
concerns.
b. Remind the mother to report concerns
after medication.