Digestive System - STUDY GUIDE
Digestive System - STUDY GUIDE
Digestive System - STUDY GUIDE
Functions:
2. Digestion- breakdown of large organic molecules into smaller molecules through mechanical and
chemical means
3. Absorption- movement of molecules out of the digestive tract and into the lymphatic system; result
from the digestive process
(1) The Oral Cavity; mouth (2) The pharynx; throat (3) The Esophagus (4) The Stomach (5) The Small and
Large Intestines (6) The Anus
(1) The Salivary Glands; empty into the oral cavity (2) The Liver (3) The Pancreas
-Serous Membrane
-Layer of Smooth Epithelial Tissue
Mesenteries – membranes that connects abdominal organs to each other and to the body wall;
connective tissue sheets that holds the organs in the abdominal cavity in place
Retroperitoneal Organs – abdominal organs that have no mesenteries; lie along the abdominal wall
Greater Omentum – mesentery connecting greater curvature; to transverse colon and posterior body
wall
The Oral Cavity:
Tongue
The Teeth
The Palate
Salivary Glands
Mucin – proteoglycan that gives lubricating quality to the secretions of the salivary glands
The Pharynx
Swallowing
(1) Bolus is a mass of food formed in the mouth and pushed into oropharynx
(2) Swallowing reflex initiated when bolus stimulates receptors in oropharynx
(3) Moves food from pharynx to stomach
-Peristalsis is a wave-like contraction that moves food through digestive tract
The Stomach
5 groups of epithelial cells
-the first group of epithelial cells consists surface mucous cells on the inner surface of the stomach and
lining the gastric pits; produces mucus
-mucous coats and protects the stomach lining
-the remaining 4 groups are located in the gastric glands; (1)mucous neck cells, (2)parietal cells,
(3)endocrine cells, (4)chief cells
(1)produces mucus(2)produces hydrochloric acids and intrinsic (3) produce regulatory chemicals
(4) produce pepsinogen, a precursor of the protein-digesting enzyme pepsin
Chyme – a paste-like substance that forms when food begins to be broken down
Hydrochloric acid – produces 2.0 pH
Pepsin – converted from its inactive form pepsinogen; breaks covalent bonds of proteins to form smaller
peptide chains
Mucus – is a thick layer that lubricates the epithelial cells of stomach wall and protects from damaging
effect of acidic chyme and pepsin
Intrinsic Factor – binds with vitamin b12 and makes it readily absorbed in small intestine
-vitamin b12 is important in deoxyribonucleic acid synthesis and red blood cell production
(1) Cephalic Phase
-6 meters long
-3 parts: (1) duodenum (2) jejunum (3) ileum
(1) 25 cm long (2) 2.5m long makes up to 2/5 of the total length of the small intestine (3) 3.5m long and
makes up 3/5 of the small intestine
-major site of digestion absorption of food
-chyme takes 3-5 hours to pass through
-contains enzymes to further breakdown food
-contains secretions for protection against chyme’s acidity
-4 major cell types: (1) absorprtive cells (2) goblet cells (3) granular cells (4) endocrine cells
(1)have microvilli produces digestive enzyme and absorve digestive food (2) produce protective mucus
(3) help protect the intestinal epithelium from bacteria (4) produce regulatory hormones
Epithelial cells are located within the tubular glands of the mucosa, these are calld Intestinal Gland or
the crypts of lieberkuhn.
The submucosa of duodenum contains mucus glands called duodenal glands which opens to the
intestinal glands
The duodenum, jejunum, and ileum are similar in structure, however, there are gradual decreases in the
diameter of the small intestine, in the thickness of the intestinal wall, in the number of circular folds,
and in the number of villi.
Ileocecal junction- the site where the ileum connects to the large intestine, it has a ring of smooth
muscle which is the ileoceca’s sphincter and the ileocecal valve which allow the intestinal contents to
move from the ileum to the large intestine but not in the opposite direction.
Processes nutrients and detoxifies harmful substances from the blood; produces digestive fluid called
the bile.
The largest internal organ of the body.
Diseases, conditions, and prodromes
Heartburn – occurs when gastric juices regurgitate into the esophagus; caused by caffeine, smoking, or
excess eating and drinking