Scribd Logo
Upload

Welcome to Scribd!

  • 20 views

    Chloroform

    Uploaded by

    Hassan Ahmed Khan
    Chloroform is a hazardous substance that can harm health if inhaled or ingested. Breathing or ingesting chloroform over long periods can damage the liver and kidneys, while high exposures by inhalation can cause dizziness and headaches. Chloroform evaporates into the air easily and breaks down slowly, with its breakdown products also being toxic. Exposure can occur by drinking contaminated water or breathing indoor air containing chloroform, especially in workplaces where it is used. The EPA limits chloroform in drinking water and requires spills over 10 pounds to be reported.

    Copyright:

    © All Rights Reserved
    Download as DOC, PDF, TXT or read online from Scribd

    Chloroform

    Uploaded by

    Hassan Ahmed Khan
    20 views3 pages
    Chloroform is a hazardous substance that can harm health if inhaled or ingested. Breathing or ingesting chloroform over long periods can damage the liver and kidneys, while high exposures by inhalation can cause dizziness and headaches. Chloroform evaporates into the air easily and breaks down slowly, with its breakdown products also being toxic. Exposure can occur by drinking contaminated water or breathing indoor air containing chloroform, especially in workplaces where it is used. The EPA limits chloroform in drinking water and requires spills over 10 pounds to be reported.

    Copyright

    © © All Rights Reserved

    Available Formats

    DOC, PDF, TXT or read online from Scribd

    Did you find this document useful?

    Is this content inappropriate?

    Chloroform is a hazardous substance that can harm health if inhaled or ingested. Breathing or ingesting chloroform over long periods can damage the liver and kidneys, while high exposures by inhalation can cause dizziness and headaches. Chloroform evaporates into the air easily and breaks down slowly, with its breakdown products also being toxic. Exposure can occur by drinking contaminated water or breathing indoor air containing chloroform, especially in workplaces where it is used. The EPA limits chloroform in drinking water and requires spills over 10 pounds to be reported.

    Copyright:

    © All Rights Reserved
    Download as DOC, PDF, TXT or read online from Scribd
    Download as doc, pdf, or txt
    20 views3 pages

    Chloroform

    Uploaded by

    Hassan Ahmed Khan
    Chloroform is a hazardous substance that can harm health if inhaled or ingested. Breathing or ingesting chloroform over long periods can damage the liver and kidneys, while high exposures by inhalation can cause dizziness and headaches. Chloroform evaporates into the air easily and breaks down slowly, with its breakdown products also being toxic. Exposure can occur by drinking contaminated water or breathing indoor air containing chloroform, especially in workplaces where it is used. The EPA limits chloroform in drinking water and requires spills over 10 pounds to be reported.

    Copyright:

    © All Rights Reserved
    Download as DOC, PDF, TXT or read online from Scribd
    Download as doc, pdf, or txt
    of 3

    Chloroform

    CAS# 67-66-3
    September 1997

    This fact sheet answers the most frequently asked health questions about chloroform. For more information, you
    may call the ATSDR Information Center at 1-888-422-8737. This fact sheet is one in a series of summaries
    about hazardous substances and their health effects. This information is important because this substance may
    harm you. The effects of exposure to any hazardous substance depend on the dose, the duration, how you are
    exposed, personal traits and habits, and whether other chemicals are present.

    HIGHLIGHTS: Exposure to chloroform can occur when breathing contaminated air or when drinking or touching
    the substance or water containing it. Breathing chloroform can cause dizziness, fatigue, and headaches.
    Breathing chloroform or ingesting chloroform over long periods of time may damage your liver and kidneys. It
    can cause sores if large amounts touch your skin. This substance has been found in at least 717 of the 1,430
    National Priorities List sites identified by the Environmental Protection Agency (EPA).
    What is chloroform?
    (Pronounced klor'eh form)
    Chloroform is a colorless liquid with a pleasant, nonirritating odor and a slightly sweet taste. It will burn only
    when it reaches very high temperatures.
    In the past, chloroform was used as an inhaled anesthetic during surgery, but it isn’t used that way today. Today,
    chloroform is used to make other chemicals and can also be formed in small amounts when chlorine is added to
    water.
    Other names for chloroform are trichloromethane and methyl trichloride.
    What happens to chloroform when it enters the environment?
     Chloroform evaporates easily into the air.
     Most of the chloroform in air breaks down eventually, but it is a slow process.
     The breakdown products in air include phosgene and hydrogen chloride, which are both toxic.
     It doesn’t stick to soil very well and can travel through soil to groundwater.
     Chloroform dissolves easily in water and some of it may break down to other chemicals.
     Chloroform lasts a long time in groundwater.
     Chloroform doesn’t appear to build up in great amounts in plants and animals.
    How might I be exposed to chloroform?
     Drinking water or beverages made using water containing chloroform.
     Breathing indoor or outdoor air containing it, especially in the workplace.
     Eating food that contains it.
     Skin contact with chloroform or water that contains it, such as in swimming pools.
    How can chloroform affect my health?
    Breathing about 900 parts of chloroform per million parts air (900 ppm) for a short time can cause dizziness,
    fatigue, and headache. Breathing air, eating food, or drinking water containing high levels of chloroform for long
    periods of time may damage your liver and kidneys. Large amounts of chloroform can cause sores when
    chloroform touches your skin.
    It isn’t known whether chloroform causes reproductive effects or birth defects in people.
    Animal studies have shown that miscarriages occurred in rats and mice that breathed air containing 30 to 300
    ppm chloroform during pregnancy and also in rats that ate chloroform during pregnancy. Offspring of rats and
    mice that breathed chloroform during pregnancy had birth defects. Abnormal sperm were found in mice that
    breathed air containing 400 ppm chloroform for a few days.
    How likely is chloroform to cause cancer?
    The Department of Health and Human Services (DHHS) has determined that chloroform may reasonably be
    anticipated to be a carcinogen.
    Rats and mice that ate food or drank water with chloroform developed cancer of the liver and kidneys.
    Is there a medical test to show whether I've been exposed to chloroform?
    Although the amounts of chloroform in the air that you exhale and in blood, urine, and body tissues can be
    measured, there is no reliable test to determine how much chloroform you have been exposed to or whether you
    will experience any harmful effects.
    The measurement of chloroform in body fluids and tissues may help to determine if you have come into contact
    with large amounts of chloroform, but these tests are useful for only a short time after you are exposed.
    Chloroform in your body might also indicate that you have come into contact with other chemicals.
    Has the federal government made recommendations to protect human health?
    The EPA drinking water limit for total trihalomethanes, a class of chemicals that includes chloroform, is 100
    micrograms per liter of water (100 µg/L).
    The EPA requires that spills or accidental releases of 10 pounds or more of chloroform into the environment be
    reported to the EPA.
    The Occupational Safety and Health Administration (OSHA) has set the maximum allowable concentration of
    chloroform in workroom air during an 8-hour workday in a 40-hour workweek at 50 ppm.
    Glossary
    Carcinogenicity: A substance with the ability to cause cancer.
    CAS: Chemical Abstracts Service.
    Ingesting: Taking food or drink into your body.
    Microgram (µg): One millionth of a gram.
    Miscarriage: Pregnancy loss.
    ppm: Parts per million.
    Source of Information
    Agency for Toxic Substances and Disease Registry (ATSDR). 1997. Toxicological profile for chloroform. Atlanta,
    GA: U.S. Department of Health and Human Services, Public Health Service.
    Animal testing is sometimes necessary to find out how toxic substances might harm people and how to treat
    people who have been exposed. Laws today protect the welfare of research animals and scientists must follow
    strict guidelines.
    Where can I get more information?
    ATSDR can tell you where to find occupational and environmental health clinics. Their specialists can recognize,
    evaluate, and treat illnesses resulting from exposure to hazardous substances. You can also contact your
    community or state health or environmental quality department if you have any more questions or concerns.
    For more information, contact:
    Agency for Toxic Substances and Disease Registry
    Division of Toxicology
    1600 Clifton Road NE, Mailstop E-29
    Atlanta, GA 30333
    Phone: 1-888-422-8737
    FAX: (404)498-0057

    External safety and chemistry information (please see our disclaimer):

    Chloroform
    CHCl3
    Stereo Image
    MDL Molfile

    NFPA Label Key

    Vermont SIRI MSDS Archive

    ATSDR Information Center / [email protected] / 1-888-422-8737


    This page last updated on June 11, 2001

    ATSDR Home | Search | Index | Glossary | Contact Us


    About ATSDR | News Archive | ToxFAQs | HazDat | Public Health Assessments
    Privacy Policy | External Links Disclaimer | Accessibility
    U.S. Department of Health and Human Services

    You might also like