NBME Embryologic Derivatives

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1. what is embryologic origin of...parafollicular cells 4th pharyngeal

pouch

2. what is embryologic origin of...thyroid diverticulum floor of primitive

pharynx

3. what is embryologic origin of...cysts or the pyramidal thyroglossal duct

lobe of thyroid. remnant

4. what is embryologic origin of...foramen cecum thyroglossal duct

remnant

5. what is embryologic origin of...pharyngeal cleft cyst persistent cervical

sinus

6. what is embryologic origin of...superior parathyroid 4th pharyngeal

gland pouch

7. what is embryologic origin of...patent foramen ovale fossa ovalis rem-

nant

8. inferonasal bleeding of the pupil is due to incomplete iris

closure of embryonic fissure of what structure?

9. what is embryologic origin of...tracheoesophageal fis- endoderm

tula

10. what is embryologic origin of...thymus, inferior 3rd pharyngeal

parathyroid pouch

11. what is embryologic origin of...pouches endoderm

12. what is embryologic origin of...clefts/grooves ectoderm

13. what is embryologic origin of...arches mesoderm

14. digeorge syndrome is due to aplasia of 3rd and 4th pha-

ryngeal pouches

15. what is embryologic origin of...craniopharyngioma

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 NBME Embryologic Derivatives
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diverticulum of the
roof of the embry-
onic oral cavity

16. what is embryologic origin of...benign cyst of anterior diverticulum of the

pituitary roof of the embry-
onic oral cavity

17. hirschsprung's disease is due to failure of what cells neural crest (eco-
to form myenteric plexus derm)

18. what is embryologic origin of...adrenal medulla neural crest (eco-

derm)

19. what is embryologic origin of...schwann cells neural crest (eco-

derm)

20. what is embryologic origin of...langerhaans cells dendritic cells

21. what is embryologic origin of...large round brain tu- meningeal

mor

22. what is embryologic origin of...pancreatic islets pre- endoderm

cursor cells

23. what is embryologic origin of...midline mass just be- tongue

low hyoid bone

24. what is embryologic origin of...thyroglossal duct cyst tongue

25. what is embryologic origin of...ovarian tumor granulosa cells

26. what is embryologic origin of...ebv mononucleosis t lymphocytes

cells

27. location of duct leading to freely mobile, soft, cystic anterior to

mass on side of neck the sternocleido-
mastoid muscle

28.

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 NBME Embryologic Derivatives
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failure of secretion of surfactant due to incomplete lung bud (endo-
differentiation of derm)

29. which structure is not yet formed as of the end of 3rd neural tube
week of pregnancy

30. failure of fusion causes cleft lip maxillary and

nasal promi-
nences

31. what structure abnormality may lead to....respiratory tracheoe-

distress in newborn with distended stomach with air sophageal septum
is due

32. failure of re-formation of duodenal lumen (choice c) is

observed in

33. failure of reformation of what structure? child with- duodenal lumen

down syndrome, abdominal distension

34. hypertrophy of what structure may lead to...nonbil- pyloric msucle

ious vomiting around 4 to 8 weeks of life with a pal-
pable abdominal mass.

35. incomplete formation of what structure may lead tracheal cartilage

to...respiratory distress, wheezing, and positional stri- rings
dor, often worse when supine.

36. abnormality of development of what structure may aortic arch

lead to....air distension not found, stridor wheezing,
cough, dysphagia, and vomiting due to compression
of the trachea and esophagus.

37. what structure receives developmental stimulus metanephros

through growth of the ureteric bud

38. what is embryologic anomaly leading to...air-fluid lev- midgut malrotation

els throughout the small intestine, suggesting a small
bowel obstruction

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39. which embryologic remnant leads to... meckel diver- vitelline duct
ticulum.

40. "which structure anomaly leads to...narrow thorax. his

ears have periauricular skin tags. he also has microg-
nathia, glossoptosis, a

41. mandibular cleft, and a short palate. tracheostomy 1st pharyngeal

relieves his respiratory distress" arch

42. "which structure contributes to...• cn vii • middle ear

hyoid bone • temporal styloid process • muscles in-
cluding the facial muscles • stapedius • platysma •

43. and stylohyoid." 2nd pharyngeal

arch

44. which structure contributes to...stylopharyngeus 3rd pharyngeal

muscle and the glossopharyngeal nerve (cranial arch
nerve ix).

45. which structure contributes to...cricothyroid muscle 4th pharyngeal

and muscles of the soft palate, as well as the thyroid arch
cartilage, a

46. which structure contributes to...intrinsic muscles of 6th pharyngeal

the larynx arch

47. which structure contributes to... pharyngeal arch

48. "which structure contributes to...hypoplasia of the

mandible and micrognathia leading to posterior

49. displacement of the tongue" 1st pharyngeal

arch

50. which structure contributes to...mandible, malleus, 1st and 2nd

maxilla, stapes, styloid process of the skull, lesser branchial arches
horn of the hyoid, and stylohyoid ligament,

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51. which structure contributes to...external acoustic 1st branchial
meatus groove

52. which structure contributes to...branchial cleft cyst 2nd, 3rd, 4th
branchial grooves

53. which structure contributes to...• middle ear cavity • 1st and 2nd
mastoid air cells • palatine tonsils. branchial pouches

54. which structure contributes to...• hyoid • criicoid • ary- 3rd, 4th branchial
tenoids • corniculate • cuneiform • thyroid • muscles arches
such as the stylopharyngeus • pharyngeal constric-
tors • the glossopharyngeal • vagus nerves.

55. which structure contributes to... thymus and inferior 3rd branchial
parathyroid glands pouch

56. which structure contributes to...superior parathyroid 4th branchial

glands. pouch

57. which structure contributes to...• maxillary • mandibu- 1st and 2nd
lar • facial nerves. branchial arches

58. which is related to...persistent conduit between the

aorta and the pulmonary artery

59. "which is related to... continuous, machine-like mur-

mur best heard in the left

60. second intercostal space, radiating to the clavicle." patent ductus arte-
riosus (pda)

61. "which is related to...concomitant ventricular septal

defect and cyanosis noted

62. in the neonatal period." persistent truncus

arteriosus

63. tetralogy of fallot

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 NBME Embryologic Derivatives
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which is related to...cyanosis first noted in infancy,
holosystolic murmur best heard in the left lower ster-
nal border.

64. which is related to... holosystolic murmur best heard vsd

in the left lower sternal border.

65. which is related to...increased blood flow through the asd

pulmonic valve and a fixed, widely split s2

66. "which is related to...• 6-month history of failure to

thrive • grade 4/6 systolic murmur caused by in-
creased pulmonic flow • followed by a fixed •

67. widely split s2 • hypertrophy of the right atrium • right vsd

ventricle • pulmonary arteries."

68. what is embryologic origin of...brain & spinal cord neural tube

69. what is embryologic origin of...neural ganglia, adrenal neural crest

medulla

70. what is embryologic origin of...peritoneum mesoderm

71. what is embryologic origin of...skull bones neural crest

72. what is embryologic origin of...epidermis, sweat & surface ectoderm

mammary glands

73. what is embryologic origin of...bladder & urethra endoderm

74. what is embryologic origin of...• cardiovascular & lym- mesoderm

phatic system • spleen & hemopoietic cells • kidney &
ureters • internal genitalia • adrenal cortex`

75. what is embryologic origin of...lungs endoderm

76. what is embryologic origin of...thyroid follicular cells neural crest

77. mesoderm

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 NBME Embryologic Derivatives
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what is embryologic origin of...muscles (skeletal, car-
diac & smooth)

78. what is embryologic origin of...middle ear epithelium endoderm

79. what is embryologic origin of...aorticopulmonary sep- neural crest

tum & endocardial cushions

80. what is embryologic origin of...branchial arches neural crest

(bones & cartilage)

81. what is embryologic origin of...retina neural tube

82. what is embryologic origin of...schwann cells; pia & neural crest
arachnoid mater

83. what is embryologic origin of...gastrointestinal tract, endoderm

liver, pancreas

84. what is embryologic origin of...lens & cornea surface ectoderm

85. what is embryologic origin of...nasal & oral epithelial surface ectoderm
linings, salivary glands

86. what is embryologic origin of...thymus, parathyroids, endoderm

thyroid follicular cells

87. what is embryologic origin of...anterior pituitary surface ectoderm

(rathke pouch)

88. what is embryologic origin of...inner ear sensory or- surface ectoderm
gans, olfactory epithelium

89. what is embryologic origin of...melanocytes neural crest

90. what is embryologic origin of...posterior pituitary, neural tube

pineal gland

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