Pharmacological Classification of Drugs

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The document discusses various drugs acting on different body systems like autonomic nervous system, respiratory system, gastrointestinal system etc. It also discusses drugs for conditions like asthma, migraine, tuberculosis.

Some of the drugs mentioned for bronchial asthma include salbutamol, ipratropium bromide, budesonide, fluticasone, montelukast, zafirlukast.

Some of the drugs mentioned for migraine include ergot alkaloids like dihydroergotamine, triptans like sumatriptan, naratriptan.

1 Drugs Acting on Autonomic Nervous System

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Anticholinergic Drugs 3

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6 Drugs Acting on Autonomic Nervous System

Preparations
1. Nicotine transdermal: NICOTINELL-TTS 10, 20, 30 cm2 patches releasing 7, 14, 21 mg nicotine per 24 hr
respectively. In those smoking > 20 cigarettes every day—start with 30 cm2 patch, shift to smaller patches every
3–5 days, treat for 3–4 weeks.
2. Nicotine chewing gum: NULIFE 1, 2, 4 mg chewing gum; In those smoking > 20 cigarettes/day—start with
4 mg gum chewed slowly for 30 min when urge to smoke occurs—gradually reduce to 2 mg gum and then 1 mg
gum. In less heavy smokers—start at lower doses.
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Adrenergic Drugs 7

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10 Drugs Acting on Autonomic Nervous System

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12 Drugs Acting on Autonomic Nervous System

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14 Drugs Acting on Autonomic Nervous System

Preparations
1. Timolol: Start with 0.25% eye drops BD, change to 0.5% drops in case of inadequate response. 0.5% OD as gel
forming solution. GLUCOMOL, OCUPRES, IOTIM, LOPRES 0.25% and 0.5% eye drops. TIMOLAST 0.5% gel
forming eye drops (long acting).
Timolol 0.5% + Latanoprost 0.005%: LAPROST PLUS, LATOCHEK-T eye drops.
2. Betaxolol: 0.5% topically in eye BD; OPTIPRES, IOBET, OCUBETA 0.5% eye drops.
3. Levobunolol: 0.5% topically in eye OD; BETAGAN 0.5% ophthalmic solution.
4. Dipivefrine: 0.1% topically in eye BD; PROPINE 0.1% eye drops.
5. Apraclonidine: 0.5–1.0% topically in eye; ALFADROPS-DS 1% eye drops.
6. Brimonidine: 0.2% topically in eye TDS;
ALPHAGAN-P, BRIMODIN-P 0.15% eye drops, IOBRIM 0.2% eye drops.

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2 Autacoids and Related Drugs

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18 Autacoids and Related Drugs

19. Mizolastine: 10 mg oral; ELINA 10 mg tab.


20. Ebastine: 10 mg oral; EBAST 10 mg tab.
21. Rupatadine: 10 mg oral; RUPAHIST 10 mg tab.
Note: For H2-Antagonists (H2-Antihistaminics) See p. 118, 119.

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Drugs for Migraine 19

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Nonsteroidal Antiinflammatory Drugs/ Antipyretic-Analgesics 23

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Antirheumatoid Drugs/Drugs for Gout 27

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3 Drugs for Respiratory Disorders

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Drugs for Bronchial Asthma 33

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4 Hormones and Related Drugs

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Thyroid Hormone and Thyroid Inhibitors 39

10. Triptorelin: For endometriosis and carcinoma prostate: 3.75­–7.5 mg of depot injection i.m. every 4 weeks;
For female infertility: 0.1 mg s.c. daily for 10 days starting on 2nd day of menstruation;
For precocious puberty: 50 µg/kg i.m. of depot injection every 4 weeks.
DECAPEPTYL DAILY 0.1 mg inj, DECAPEPTYL DEPOT 3.75 mg inj.
11. Leuprolide: For palliative treatment of advanced carcinoma prostate—1 mg s.c. OD or 3.75 mg i.m./s.c. once
a month of depot preparation; LUPRIDE 1 mg inj, 3.75 mg depot inj, PROGTASE 1 mg/ml inj.

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42 Hormones and Related Drugs

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44 Hormones and Related Drugs

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Androgens and Related Drugs 47
18. Hydrocortisone acetate 0.1–1.0% LYCORTIN 1% oint., in CORTOQUINOL 1% with quiniodochlor, 4% cream,
GENTACYN-HC TOPICAL 1% with gentamicin 0.1%, CORTISON-KEMICETINE 0.5% with chloramphenicol 0.5%.
19. Hydrocortisone butyrate 0.001%
LOCOID cream

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50 Hormones and Related Drugs

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Progestins 53

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Hormonal Contraceptives 55

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58 Hormones and Related Drugs

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5 Drugs Acting on Peripheral (somatic) Nervous System

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62 Drugs Acting on Peripheral (somatic) Nervous System

15. Baclofen: 10 mg BD–25 mg TDS oral; LIORESAL, LIOFEN 10, 25 mg tabs.


16. Thiocolchicoside: 4 mg TDS-QID; NUCOXIA-MR: thiocolchicoside 4 mg + etoricoxib 60 mg tabs.
17. Tizanidine: 2 mg TDS; max 24 mg/day; SIRDALUD 2, 4, 6 mg tab; TIZAN 2, 4 mg tab; BRUFEN-MR, TIZAFEN
2 mg + ibuprofen 400 mg tab; TIZANAC 2 mg + diclofenac 50 mg tab., PROXYVON-MR 2 mg + nimesulide 100 mg cap.

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6 Drugs Acting on Central Nervous System

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66 Drugs Acting on Central Nervous System

Preanaesthetic Medication Drugs


Note: See Index for preparations

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Sedative-Hypnotic Drugs 67

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Antiepileptic Drugs 69

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72 Drugs Acting on Central Nervous System

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Antipsychotic Drugs 75

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Drugs for Mania and Bipolar Disorder 77

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Antidepressants 79

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Antianxiety Drugs 81
18. Trazodone: 50–200 mg/day; TRAZODAC 25, 50 mg tab, TRAZONIL, TRAZALON 25, 50, 100 mg tabs.
19. Mianserin: 30–100 mg/day; TETRADEP 10, 20, 30 mg tab, SERIDAC 10, 30 mg tab.
20. Bupropion: 150–300 mg/day; SMOQUIT–SR, BUPRON–SR 150 mg tab.
21. Mirtazapine: 15–45 mg/day; MIRT 15, 30, 45 mg tabs, MIRTAZ 15, 30 mg tab.
22. Venlafaxine: 75–150 mg/day; VENLOR 25, 37.5, 75 mg tabs, VENIZ-XR 37.5, 75, 150 mg ER caps.
23. Tianeptine: 12.5 mg BD–TDS; STABLON 12.5 mg tab.
24. Amineptine: 100 mg BD at breakfast and lunch; SURVECTOR 100 mg tab.
25. Duloxetine: 30–80 mg/day; DELOK, DULANE, DUZAC 20, 30, 40 mg caps.

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CNS Stimulants and Cognition Enhancers 85

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7 Cardiovascular Drugs

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Antihypertensive Drugs 89

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Antianginal Drugs 93

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Drugs for Peripheral Vascular Diseases 95

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Drugs for Congestive Heart Failure 97

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Antiarrhythmic Drugs 99

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8 Drugs Acting on Kidney

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9 Drugs Affecting Blood

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Anticoagulants 111

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Fibrinolytics/ Antifibrinolytics/Antiplatelet Drugs 113
6. Acenocoumarol (Nicoumalone): 8–12 mg followed by 2–8 mg/day; ACITROM, NISTROM 1, 2, 4 mg tabs.
7. Ethylbiscoum acetate: 900 mg followed by 300–600 mg/day.
8. Sodium citrate: 1.65 g for 350 ml of blood (for transfusion); ANTICOAGULANT ACID CITRATE DEXTROSE
SOLUTION 2.2 g/100 ml (75 ml is used for 1 unit of blood).
9. Sodium oxalate: 10 mg for 1 ml blood (for blood counts etc.).
10. Sodium edetate: 2 mg for 1 ml blood (for investigations).

Fibrinolytes (Thrombolytes): Streptokinase, Alteplase, Urokinase, Reteplase


Antifibrinolytes Agents: Epsilon-amino Caproic acid (EACA) & Tranexamic acid

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116 Drugs Affecting Blood

Preparations
1. Lovastatin: 10–40 mg/day; ROVACOR, AZTATIN, LOVAMEG 10, 20 mg tabs.
2. Simvastatin: 5–20 mg/day (max 80 mg); SIMVOTIN, SIMCARD, ZOSTA 5, 10, 20 mg tabs.
3. Pravastatin: 10–40 mg/day; PRAVATOR 10, 20 mg tabs.
4. Atorvastatin: 10–40 mg/day (max 80 mg); AZTOR, ATORVA, ATORLIP 5, 10, 20 mg tabs.
5. Rosuvastatin: 5–20 mg/day (max. 40 mg/day);
46 ROSUVAS, ROSYN 5, 10, 20 mg tab.
10 Gastrointestinal Drugs

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122 Gastrointestinal Drugs

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Laxatives 125

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128 Gastrointestinal Drugs

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11
130
Antibacterial Drugs

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Sulfonamides/Quinolone Antimicrobials 131

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134 Antibacterial Drugs

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Cephalosporins 137

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Antitubercular Drugs 145

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Antitubercular/Antileprotic Drugs 147

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12 Antifungal, Antiviral, Antiprotozoal and Anthelmintic Drugs

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Antiviral Drugs (Non-retroviral) 153

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154 Antifungal, Antiviral, Antiprotozoal and Anthelmintic Drugs

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158 Antifungal, Antiviral, Antiprotozoal and Anthelmintic Drugs

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162 Antifungal, Antiviral, Antiprotozoal and Anthelmintic Drugs

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166 Antifungal, Antiviral, Antiprotozoal and Anthelmintic Drugs

Combinations
1. Liposomal amphotericin B (5 mg/kg i.v. infusion single dose) + Miltefosine (100 mg/day oral for 7 days)
2. Liposomal amphotericin B (5 mg/kg i.v. infusion single dose) + Paromomycin (15 mg/kg i.m. daily for 10 days)
3. Miltefosine (100 mg/day oral for 10 days) + Paromomycin (15 mg/kg i.m. daily for 10 days).

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13 Anticancer Drugs (Antineoplastic Drugs)

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170 Anticancer Drugs (Antineoplastic Drugs)

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Anticancer Drugs 171

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14
176
Miscellaneous Drugs

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184 Miscellaneous Drugs

Preparations
1. Benzoyl peroxide: 2.5–10% topical application;
PERSOL, PERNOX, BENZAC-AC 2.5% and 5% gel; in PERSOL FORTE 10% cream with sulfur ppt. 5%.
2. Tretinoin (Retinoic acid, all trans vitamin A acid): 0.025%–0.05% topical application;
EUDYNA 0.05% cream, RETINO-A 0.025% and 0.05% cream.
3. Adapalene: 0.1% topical application once daily at bed time; ADAFERIN, ADAPEN, ACLENE 0.1% gel.
4. Azelaic acid: 10–20% topical application; AZIDERM 10%, 20% cream.
5. Erythromycin: 2–4% topical application; ACNEDERM
67 2% lotion and oint; ERYTOP 3% lotion and cream;
EROMED 2% lotion, 4% gel, ACNELAC-Z 4% lotion and gel with zinc acetate 2%.
Vaccines 189

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