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    Table 4-16 - Use of Mood Stabilizing Medications For Bipolar

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    Dragutin Petrić

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    Table 4-16 - Use of Mood Stabilizing Medications For Bipolar

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    Table 4-16_Use of Mood Stabilizing Medications for Bipolar

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    Table 4-16 - Use of Mood Stabilizing Medications For Bipolar

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    Dragutin Petrić

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    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
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    Essentials of Psychiatry in Primary Care: Behavioral Health in the Medical Setting >Major Depression and

    Related Disorders
    Robert C. Smith, Gerald G. Osborn, Francesca C. Dwamena, Dale D'Mello, Laura Freilich, Heather S. Laird-Fick+
    Table 4-16.Use of Mood Stabilizing Medications for Bipolar Disorders

    Indications Starting Dose (mg/d) Titration Target Dose Side Effects Comment

    Stevens-Johnson
    syndrome

    Lamotrigine 25/d × 2 wk; then 50/d × 2


    Depression “Rash” Instruct patients to report
    25 daily wk; then 100/d × 2 wk, 200-300 per day
    any rash immediately
    Lamictal then 200/d
    Maintenance Hepatitis

    Anemia, leukopenia,
    thrombocytopenia

    Encephalopathy

    Increased ammonia
    Obtain at baseline and
    Divalproex sodium Reaches steady state in 5
    Mania/hypomania Serum valproic acid level every 3 mo: valproic acid
    500-1000 twice daily d; can increase 500- Thrombocytopenia
    of 85-125 µg/mL level, liver functions, and
    Depakote 1000/d as tolerated
    Maintenance CBC
    Hepatitis, pancreatitis

    Sedation, weight gain,


    tremor

    Stevens-Johnson
    syndrome

    Obtain at baseline and


    Reaches steady state in Hyponatremia
    Carbamazepine every 3 months:
    Mania/hypomania 3-4 d; increase by 200/d
    200 ER twice daily carbamazepine level,
    Maintenance as tolerated; maximum = Hepatitis
    Tegretol serum sodium, liver
    1600/d
    functions, and CBC
    Pancytopenia

    Vertigo, somnolence

    Date of download: 12/26/22 from AccessMedicine: accessmedicine.mhmedical.com, Copyright © McGraw Hill. All rights reserved.

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