DETAILED LESSON PLAN
In
EARTH AND LIFE SCIENCE
I. OBJECTIVES
A. Content Standards The learners demonstrate understanding of plant and animal reproduction; how
genes work and how genetic engineering is used to produce novel products.
B. Performance Standard The learners shall be able to conduct a survey of products containing substances
that can trigger genetic disorders such as phenylketonuria.
C. Learning The learners describe the process of genetic engineering. (S11/12LT-IIej-
Competencies/Objectives 17)
II. CONTENT Genetic Engineering
III. LEARNING RESOURCES
A. References
1. Teacher’s Guide Pages Teaching Guide for Senior High School –Earth and Life Science. The Commission
on Higher Education in collaboration with the Philippine Normal University, pages
215-218.
2. Learner’s Materials Pages Earth and Life Science Activity Sheet Quarter 2 MELC 4 Week 4 – Genetic
Engineering
3. Textbook Pages
4. Additional Materials from
Learning Resource (LR) Portal
B. Other Learning Resources
IV. PROCEDURES Teacher’s Activity Student’s Activity
A. Reviewing previous lesson Previously, we have discussed
or presenting a new lesson about the DNA- the genetic
material for all living things.
Being the genetic material, it
carries traits from parents to
offspring.
DNA is helical or spiral.
As a review, how does a DNA
appear?
It is composed of a sugar called deoxyribose, a
What are its components? phosphate group and nitrogenous bases –
adenine, thymine, cytosine and guanine.
Very good.
B. Establishing a purpose for Today, we are going to learn
the lesson about the process of genetic
engineering.
C. Presenting Do you know any Yes. (Answers may vary.)
Examples/instances of the superheroes?
new lesson
What makes them different
They have superpowers.
from other people?
If you are given a chance to be
a superhero, what superpower (Answers may vary.)
would you have and what
changes in your body will you
need?
D. Discussing new concepts Before we go further in our
and practicing new skills #1 discussion, let us first define
the following terms related to
genetic engineering:
Genetic Engineering – it is the
manipulation or change of the
genetic material of an
organism using varied
technologies.
It has applications in medicine,
research, industry and
agriculture, and can be used
on a wide range of plants,
animals and microorganisms.
Specifically, involves the
transfer of genes or parts of
DNA from one organism to
another.
Recombinant DNA - the DNA
that has been changed
through genetic engineering,
and which now contains
genetic material from two
different species
Recombinant Organism - the
organism to which the new
gene has been added,
transgenic organism or
genetically-modified organism
(GMO).
After knowing the definition of
the keywords, the next
question is – Why undergo
genetic engineering?
E. Discussing new concepts Now that we have defined
and practicing new skills #2 these terms, we are going to
proceed with the process of
genetic engineering.
The following are the steps:
1. Identification and Cutting of
Gene Segment
2. Making of Multiple Copies
of the Gene
3. Introduction of the Gene
into a Bacterial Plasmid
4. Production of a
Recombinant DNA
F. Developing Mastery (Lead Based on these descriptions, (Insert illustration)
to Formative Assessment #3 which steps corresponds to
(Two student volunteers will be asked to
the illustration shown?
arrange the steps of the process and present it
in class.)
G. Finding practical Are you familiar with insulin? Yes. (Answers may vary)
applications of concepts and
Did you know that one of the
skills in daily living
first successful applications of
genetic engineering was the
production of human insulin
from the bacterium
Escherichia coli?
Based on the steps in the
process of genetic engineering (Insert flow chart)
presented earlier, can you give
the steps involved in the
production of human insulin
and fill in the flow chart? Step 1 is identification of the human gene
needed by the human body to create insulin.
Step 2 is the creation of the gene in multiple
copies in a laboratory.
Step 3 is the insertion of the gene in the
bacterial plasmid.
Step 4 is the return of the plasmid with
segment of DNA or gene to the bacterium
creating a recombinant bacterium that is able
to produce insulin.
Step 5 is the cloning of the bacterium and the
colony of bacterium formed is placed in
fermentation tanks to produce insulin at a large
scale.
H. Making generalization and As a recap, we have discussed
genetic engineering, terms
abstractions about the lesson
related and the steps involved,
as well as cited some
examples.
What are the key terms
related to genetic Recombinant DNA, Recombinant organism
engineering?
What are the key steps in the 1. Identification and Cutting of Gene Segment
process?
2. Making of Multiple Copies of the Gene
3. Introduction of the Gene into a Bacterial
Plasmid
4. Production of a Recombinant DNA
How does genetic engineering Genetic engineering is helpful in variety of ways
help people and science, in such as in the field of medicine, research,
general? industry and agriculture and can be used on a
wide range of plants, animals and
microorganisms.
I. Evaluating learning Given the following situation,
describe the steps undergone
to produce the genetically
modified organism.
The Philippines has become
the first country to approve
the commercial production of
the nutrient-enriched Golden
Rice.
J. Additional Activities for
Application or Remediation
V. REMARKS
A. No. of Learners who
earned 80% in the evaluation
B. No. of learners who require
additional activities for
Remediation
C. Did the remedial lessons
work? No. of learners who
have caught up with the
lesson
D. No. of learners who
continue to require
remediation
Prepared by:
LADY GEM H. MAQUIRANG
Teacher II
Appendices
Rubric for Concept Map
Exceeds Adequately
Exemplary Below Standard
Standard Meets Standard Student Score
4 1
3 2
Thoughtfully
Somewhat
organized
organized Choppy and
Well Organized Easy to
Somewhat confusing
Logical Format follow most
incoherent Contains
Organization Contains all of of the time _____
Contains limited
the concepts Contains
only a few of number of
needed most of the
the needed concepts
concepts
concepts
needed
Linking
Linking
words are
Linking words words are
clear but
demonstrate high easy to Difficult to
Content ideas are _____
conceptual follow but at follow
majority of
understanding times ideas
the ideas are
are unclear
unclear
