(Transverse Myelitis Associated With Anti-Influenza A (H1N1) Vaccination) - PubMed

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8/5/22, 6:56 PM [Transverse myelitis associated with anti-influenza A (H1N1) vaccination] - PubMed

Case Reports
Medicina (B Aires). 2011;71(2):161-4.

[Transverse myelitis associated with anti-influenza


A (H1N1) vaccination]
[Article in
Spanish]
María Florencia Arcondo  1 , Adolfo Wachs, Marcelo Zylberman

Affiliations
PMID:
21550934

Abstract
Transverse myelitis is an inflammatory disorder characterized by spinal cord dysfunction. Infectious,
autoimmune, postinfectious and postvaccination diseases are the most common recognized causes of
transverse myelitis, but near 50% of the cases are finally assumed as idiopathic. Rubeolla, mumps,
rabies and influenza vaccines were associated with many neurologic complications, such as Guillain
Barré Syndrome, acute disseminated encephalomyelitis (ADEM) and transverse myelitis. As a
prevention measure after the 2009 pandemia, in February 2010 a National Campaigne of Vaccination
against the Influenza A (H1N1) was started in our country. We report a case of a woman who received
a monovalent Influenza A (H1N1) vaccine and four days after, began with sensory symptoms that
progressed to a clear defined sensory level. She reached the clinical criteria of transverse myelitis,
according to the Transverse Myelitis Consortium Working Group. One month later, the patient
remained clinically stable and the MRI showed an improvement of the image without corticosteroids
treatment. We discuss diagnostic, prognostic and therapeutic aspects of this clinical entity.

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