Prenatal Care
Prenatal Care
Prenatal Care
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After pregnancy is confirmed, it is extraordinarily important to determine the duration of pregnancy and the estimated date of confinement (EDC). Further care is heavily
predicated on this estimate. The history begins with ascertaining the first day of the last normal menstrual period and calculating the EDC by assuming duration of
pregnancy averages 280 days (40 weeks). Because a first-trimester dating ultrasound (US) is accurate to within 5 days at confirmation or determination of an accurate
EDC, its value cannot be overestimated.
The documentation of prior obstetric history includes prior complications, route of delivery, and estimated birth weights. Maternal medical disorders are often
exacerbated by pregnancy; cardiovascular, renal, and endocrine disorders require evaluation and counseling concerning possible treatments required. A history of
previous gynecologic surgery, including cesarean delivery, is important to consider. A family history of twinning, diabetes mellitus, familial disorders, or hereditary
disease is relevant.
Current medications (prescription and nonprescription) are reviewed, along with any herbals or supplements. Certain prescription medications are known teratogens and
should be discontinued. Examples include isotretinoin (Accutane), tetracycline (Sumycin), quinolone antibiotics (ciprofloxacin [Cipro], levofloxacin [Levaquin]),
“statin” cholesterol-lowering medications such as atorvastatin (Lipitor) and rosuvastatin (Crestor) and warfarin (Coumadin). Angiotensin-converting enzyme (ACE)
inhibitors and angiotensin receptor blockers (ARBs) should not be used in pregnancy because they can be associated with fetal renal agenesis.
It is important to determine the pregnant patient’s risks for developing preeclampsia during the first trimester prenatal visit because starting low dose aspirin (81 mg)
between 12 to 28 weeks (ideally before 16 weeks’ gestation) can prevent morbidity and mortality from preeclampsia. One or more of the following high-risk factors is
an indication for beginning low dose aspirin after 12 weeks: a history of previous preeclampsia, multifetal gestation, renal disease, autoimmune disease, diabetes, and
chronic hypertension. Consideration of low dose aspirin should be given for patients with more than one of moderate-risk factors for preeclampsia including obesity,
advanced maternal age, history of low birth weight infants or adverse birth outcomes, and low socioeconomic status or African American race.
Open discussion of substance abuse (alcohol, tobacco, and illicit drugs) is an integral part of the patient interview. Counseling patients about smoking cessation is vital
in early pregnancy. Smoking increases the risk of fetal death or damage in utero. It is also associated with increased risk of placental abruption and placenta previa, each
of which put both mother and child at risk, along with premature birth. The interest that pregnant women have in delivering a healthy infant can be a potent motivator for
change at this point.
View chapter on ClinicalKey
Screening, Prenatal
T.A. Lenzi, T.R.B. Johnson, in Encyclopedia of Infant and Early Childhood Development, 2008
Introduction
Prenatal care has existed for over 100 years as an approach to improve maternal and newborn outcomes. Traditionally, risk factors such as family history, social and
behavioral factors, and the identification of existing risk factors (sexually transmitted disease, anemia, blood incompatibility) and intercurrent problems such as
hypertension, fetal growth restriction, and pre-term labor have been the core of prenatal care. With advances in knowledge and tools of modern genetics, a major
emphasis has become prenatal and recently preconception screening of hereditable diseases. The goal of prenatal screening is to counsel patients about their screening
and diagnostic options, to provide reassurance to patients at low risk, and to identify high-risk patients who may benefit from diagnostic or therapeutic procedures.