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Lesson Plan DNA Replication

This lesson plan outlines a science lesson on DNA replication for 10th grade students. The objective is for students to demonstrate DNA replication by creating a model of a DNA template and determining the sequence of bases in the new DNA strand. Students will review components of DNA and nucleotides. They will then watch a video on cell division and answer guide questions. Next, students will complete a hands-on activity where they build DNA strands using colored shapes, separate the strands, and rebuild them to model replication. Finally, students will answer post-activity questions and take a short evaluation quiz.

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Queencess Ara Torres
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1K views3 pages

Lesson Plan DNA Replication

This lesson plan outlines a science lesson on DNA replication for 10th grade students. The objective is for students to demonstrate DNA replication by creating a model of a DNA template and determining the sequence of bases in the new DNA strand. Students will review components of DNA and nucleotides. They will then watch a video on cell division and answer guide questions. Next, students will complete a hands-on activity where they build DNA strands using colored shapes, separate the strands, and rebuild them to model replication. Finally, students will answer post-activity questions and take a short evaluation quiz.

Uploaded by

Queencess Ara Torres
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOCX, PDF, TXT or read online on Scribd
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Republic of the Philippines

Department of Education
Division of Nueva Ecija
Nueva Ecija High School
Cabanatuan City

Lesson Plan 3rd Quarter


Science 10 01/10/2017

I. Objective
To demonstrate the replication of DNA molecule by creating a model creating a model of a DNA
template to determine the sequence bases in the new DNA strand.

II. Subject Matter


a. Topic:
DNA Replication
b. Reference:
G10/ Science Learner’s Material pp. 268-272, G10 Science Teacher’s Guide pp. 195-198
c. Materials:
TV/Monitor/Projector, Slideshow Presentation, Activity Sheets
d. Science Concepts
- DNA is made of nucleotides containing sugars, phosphate groups, and
nitrogenous bases with a double helix shape.
- The complementary structure of DNA’s two strand allow each strand to serve as
template during replication
- The specificity of base pairing in DNA, adenine with thymine, and cytosine with
guanine, allows the DNA to replicate itself with accuracy

III. Learning Tasks


a. Daily Routine
Greetings and checking of attendance

b. Review
What are the components of a nucleic acid?
What are the components of a nucleotide?
What is DNA?
How is DNA different from RNA?

c. Motivation
Video of Cell Division
Guide Questions:
 What have you noticed on the video?
 Do you think that the cells produced during the division are unique with each other or
not? The cells that are produced during cell division are actually identical with each other
since they came from the same parent cell and must contain the same genetic information.

d. Lesson proper
Pre-Activity
Unlocking of difficulties
 DNA Replication –
 Nitrogenous Bases – Adenine, Thymine, Guanine, Cytosine
 Chargaff’s Rule – Adenine pairs with Thymine; Cytosine pairs with Guanine
 Semi-conservative replication –

Distribution of activity sheets and materials


Activity
DNA Makes DNA

Objective:
• Make a model of a DNA template to determine the sequence of bases in the new DNA strand.

Materials:
• Crayons
• Scissors
• paste/tape
• 1/4 size illustration board or long size folder

Procedure:
1. Use the patterns of the components of the DNA provided by your teacher. Color code
phosphate = blue, deoxyribose sugar = green and bases as follows: adenine = yellow, thymine
= pink, guanine = violet and cytosine = red.
2. Cut out the shapes of each nucleotide.
3. Build a model of a strand of a DNA molecule. The strand should contain 6 base “rungs”
following the given order of the nucleotides below.

Guanine
Adenine
Cytosine
Thymine
Cytosine
Guanine

4. Tape the cut out pattern to form the nucleotides.


5. Let this arrangement represent the left half of your DNA molecule.
6. Make a complementary strand for the first strand that you made in step3.
7. Tape the cut-out pattern forming nucleotides for the second strand of the DNA molecule.
8. Match the bases of the first strand and the second strand. Do not tape across bases.
9. Once you have made your DNA model, separate the two strands of the DNA model down the
middle so that there are now two single strands of DNA.
10. Create new double-stranded DNA by matching complementary nucleotides to the bases on
each single strand.
11. Tape and then cut out the pattern forming the nucleotides for each of the single nucleotides.
12. When you are finished, mount the original DNA model and the DNA model with its
complementary strand in the illustration board or folder.

Post-Activity
Guide Questions:
 Compare the two new strands of DNA. Are they the same or different? Why?
 How do the nucleotides in DNA pair?
 How do you compare a DNA molecule to a zipper?
 How is information from the DNA passed on from one cell to another?

e. Application
 How does the structure of a DNA molecule help account for the great variety of life that
exists on earth?
 What might happen if DNA failed to replicate itself properly?

f. Generalization
Guide Questions:
 How do bases pair-up with each other?
 How does the specificity of the base pairing helps with the accuracy of DNA replication?
 What would be the outcome of DNA replication?
g. Evaluation
1. Which of the following base may pair-up with guanine?
a. adenine b. thymine c. cytosine d. uracil

2. Which of the following is the correct complementary strand with the parent strand
“CGCATAA”?
a. AATACGC b. GCGTATA c. CGCTATT d. GCGTATT

3. Which of the following is not present in a DNA molecule?


a. deoxyribose b. uracil c. phosphate d. guanine

4. Which of the following base pair is incorrect?


a. T-A b. C-G c. T-G d. G-C

5. Determine the DNA strands that don’t complement each other.


a. CTACGTC b. ATACGCA c. ACGCTGC d. GTCGCTA
GATGCAG TATGCCT TGCGACG CAGCGAT

h. Assignment
Do research on the processes involved in RNA transcription.

Prepared by:

MARK ANGELO A. DE JESUS


Teacher I

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