M.Sc. Chemistry KUD (Constituent and Affiliated Colleges)

KARNATAK UNIVERSITY
M. Sc. Chemistry
Choice Based Credit System

(CBCS)
Revised Syllabus
(w.e.f. 2019-20)
Basis for Internal Assessment:
Internal assessment marks in theory papers shall be based on tests. The tests may be conducted 8
to 12 weeks after the start of a semester. Internal assessment marks in practicals shall be based
on tests. The practical test may be conducted 10 weeks after the start of a semester
Theory Question Paper Format for CBCS Semester Examinations:
Q: 1 (Compulsory)
Seven sub questions carry two marks each and one sub question to be answered of one mark (2
questions from each unit)
15 marks
Q: 2 to Q: 7
Six questions from four units will be given. Each question carries 15 marks. Any four questions
are to be answered. There may be mixing of questions from different units.
15x4 = 60 marks
Total: 75 marks
The other general academic regulations will be same as laid by University
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KARNATAK UNIVERSITY, DHARWAD
M.Sc. DEGREE PROGRAMME IN CHEMISTRY
(With effect from 2019-20)
(CBCS)
Course Structure and Scheme of Examination:
FIRST SEMESTER
No. of Duration of Internal

Hrs/ exam. in Assessment Marks
Description of Papers Credits week Hrs Marks at the Total
Theory/ Theory/ Theory/ exams. Marks
Practical Practical Practical
A. Core Subjects
CHGT1.1: Inorganic ChemistryI 4 4 3 25 75 100
CHGT1.2: Organic ChemistryI 4 4 3 25 75 100
CHGT1.3: Physical Chemistry I 4 4 3 25 75 100
CHGT1.4: Analytical Chemistry 4 4 3 25 75 100
B. Practical
CHG(Pr)1.5: Lab Course in Inorganic 2 4 4 10 40 50

Chemistry
CHG(Pr) 1.6: Lab Course in Organic 2 4 4 10 40 50
Chemistry
CHG(Pr) 1.7: Lab Course in Physical 2 4 4 10 40 50
Chemistry
CHG(Pr) 1.8: Lab Course in Analytical 2 4 4 10 40 50
Chemistry
Total 24 32 28 140 460 600
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SECOND SEMESTER
No. of Duration Internal

Hrs/ week of exam. Assessment Marks
Description of Papers Credits Theory/ in Hrs Marks at the Total
Practical Theory/ Theory/ exams. Marks
Practical Practical
A. Core Subjects
CHGT2.1: Inorganic ChemistryII 4 4 3 25 75 100
CHGT2.2: Organic ChemistryII 4 4 3 25 75 100
CHGT2.3: Physical ChemistryII 4 4 3 25 75 100
B. Elective
CHET-2.1: Applied Inorganic Chemistry
C. Practical
CHG(Pr) 2.4: Lab Course in 2 4 4 10 40 50

Inorganic Chemistry
Organic Chemistry
Physical Chemistry
Total 22 28 24 130 420 550
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THIRD SEMESTER
No. of Hrs/ Duration Internal

week of exam. Assessm Marks
Description of Papers Credits Theory/ in Hrs ent at the Total
Practical Theory/ Marks exams. Marks
Practical Theory/
Practical
A. Core Subjects
Inorganic Chemistry
CHGT3.1: Inorganic Chemistry 4 4 3 25 75 100
CHGT3.2: Organic Chemistry 4 4 3 25 75 100
CHGT3.3: Physical Chemistry 4 4 3 25 75 100
B. Elective
CHEOT-3.1: Applied Organic Chemistry

OR
CHEPT-3.1: Applied Physical Chemistry
C. Practical

Chemistry
CHG(Pr)3.5: Lab Course in Organic 2 4 4 10 40 50
Chemistry
CHG(Pr)3.6: Lab Course in Physical 2 4 4 10 40 50
Chemistry
Total 22 28 24 130 420 550
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FOURTH SEMESTER
Duration Internal
No. of of exam. Assessment
Description of Papers Credits Hrs/ week in Hrs Marks Marks Total
Theory/ Theory/ Theory/ at the Marks
Practical Practical Practical exams.
A. Core Subjects
Inorganic Chemistry
CHGT4.1: Inorganic Chemistry 4 4 3 25 75 100
CHGT4.2: Organic Chemistry 4 4 3 25 75 100
CHGT4.3: Physical Chemistry 4 4 3 25 75 100
CHGP4.4: Project Work* 6 4 8 25 125** 150

Inorganic Chemistry/Organic
Chemistry/Physical Chemistry
Practical

Chemistry
CHG(Pr)4.6: Lab Course in Organic 2 4 4 10 40 50

Chemistry
CHG(Pr)4.7: Lab Course in Physical 2 4 4 10 40 50

Chemistry
Total 24 28 21 130 395 600
** Project Evaluation:
Dissertation  75 Marks
Presentation/  50 Marks
Viva-Voce
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KARNATAK UNIVERSITY, DHARWAD
SYLLABUS FOR M.Sc. CHEMISTRY
CHOICE BASED CREDIT SYSTEM

(CBCS)
(With effect from 2019-20)
SEMESTER–I
CHGT1.1: INORGANIC CHEMISTRYI
UNITI
Structures and Energetics of Ionic Crystals and Covalent Bonds:
Ionic Bond: Properties of ionic compounds, crystal lattices, closed packed structures,
coordination number of an ion, radius ratio rule, structures of crystal lattices- NaCl, CsCl, ZnS
and rutile. Lattice energy: Born Lande equation, Born-Haber cycle, uses of Born-Haber type of
calculations. Covalent character in ionic bonds, Fajan’s rules, hydration energy and solubility of
ionic solids.
Covalent Bond: Valence bond theory, resonance, hybridization and energetics of hybridization.
VSEPR theory: Deduction of molecular shapes. MOT of homo and heteronuclear molecules and
MO treatment for the molecules involving delocalized π-bonding (CO32, NO3 and CO2).
Walsh diagrams and Bent’s rule.
(12 Hours)
UNITII
Coordination Chemistry:
Coordination numbers 210 and their geometries. Crystal field theory of coordination
compounds: octahedral, square planar, tetrahedral, trigonal bipyramidal and square pyramidal
fields, measurement of 10 Dq and factors affecting it, CFSE, Spectrochemical series and
JahnTeller effect.
Structural evidences for ligand field splitting: hydration, ligation and lattice energies. Evidences
for covalency in ML bonding. MO theory of coordination compounds: MO energy level
diagrams for octahedral and tetrahedral complexes without and with pi-bonding.
Electronic Spectra: Spectroscopic ground terms, Orgel diagrams for transition metal
complexes(Td &Oh).
Magnetism: Types, spin moment, spinorbit coupling.
(12 Hours)
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UNITIII
Stability of Metal Complexes, Concepts of Acids and Bases and Non-aqueous Solvents:
Stability of Complexes: Stepwise and overall formation constants, factors affecting stability of
metal complexes, determination of stability constants of metal complexes by spectrophotometric
and polarographic methods.
Concept of Acids and Bases: Theories of acids and bases, Bronsted and Lewis acids and bases,
LuxFlood theory, leveling effect of solvents, hardness and softness, HSAB concept and its
applications.
Non-aqueous solvents: Classification of solvents, properties of non-aqueous solvents. Reactions

in non-aqueous media: Liquid ammonia, anhydrous sulphuric acid, anhydrous HF, liquid sulphur
dioxide. Super acids.
(12 Hours)
UNITIV
Solid State Chemistry:
Crystal lattice: Unit Cell, Miller indices and planes, X-ray diffraction method, molecular solids,
hydrogen bonding, metallic, covalent and ionic solids; structural classification of binary and
tertiary compounds, determination simple structure, spinel and perosvskite structures.
Band theory, conductors, semiconductors and insulators, energy bands, intrinsic and extrinsic
semiconductors.
Perfect and imperfect crystals, intrinsic and extrinsic defects- point, line and plane defects.
Vacancy, Schottky and Frenkel defects. Schottky and Frenkel defect formation, colour centres,
nonstoichiometry.
(12 Hours)
Total 48 Hours
Recommended Books:
1. Inorganic ChemistryPrinciples of Structure and Reactivity, 4thEdnJ. E. Huheey, E.A.

Keiter, R. L. Keiter and O.K. Medhi. Pearson Education (2009).
2. Shriver & Atkins’ Inorganic Chemistry, 5th EdnP. Atkins, Tina Overton, J. Rourke, Mark
Weller and F. Armstrong.Oxford University Press (2010)
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3. Inorganic Chemistry, 2nd Edn. Catherine E. Housecroft and A.G. Sharpe, Pearson Prentice
Hall (2005)
4. Concise Inorganic ChemistryJ. D. Lee, 5th Edn, New Age International (1996).
5. Solid State Chemistry and its ApplicationsA. R. West, JohnWiley and sons.
6. Solid state ChemistryN. B. Hannay, PrenticeHall of India Pvt. Ltd. New Delhi.
CHG(Pr)1.5: Lab Course in Inorganic Chemistry
1. Determination of iron in hematite ore using cerium(IV) solution (0.02M) as the titrant and
gravimetric determination of insoluble residue.
2. Determination of calcium and magnesium carbonates in dolomite ore using EDTA titration
and gravimetric analysis of insoluble residue.
3. Quantitative analysis of copper-nickel in alloy/mixture:

i. Copper volumetrically using KIO3
ii. Nickel gravimetrically using DMG
4. Determination of lead and tin in a mixture: Analysis of solder using EDTA.
5. Determination of Cr(III) and Fe(III) in a mixture: Kinetic masking.
6. Quantitative determination of iron(III) gravimetrically and calcium(II) volumetrically in a

mixture.
7. Determination of iron(II) and nickel (II) in a mixture:

i. Iron(II) volumetrically using K2Cr2O7 solution
ii. Nickel gravimetrically using DMG solution
8. Quantitative analysis of chloride and iodide in a mixture:

i. Iodide volumetrically using KIO3
ii. Total halide gravimetrically
9. Preparation of complexes:
i) Tris (thiourea) copper(I)sulphate monohydrate and
ii) Tris (oxalato) aluminate (III)
Scheme of Examination:
1. Duration of Examination : 4 hours

2. Experiment : 35 marks
3. Viva-voce and Journal : 05 marks
4. Internal assessment : 10 marks
Total : 50 marks
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Recommended Books:
1. Fundamental of Analytical Chemistry, D.A. Skoog, D.M. West, Holler and Crouch 8th
edition, 2005, Saunders College Publishing, New York.
2. Analytical Chemistry, G.D. Christian, 5th edition, 2001 John Wiley & Sons, Inc, India.
3. Vogel’s Textbook of Quantitative Chemical Analysis, J. Mendham, R.C. Denney, J.D
4. Barnes and M.J.K. Thomas, 6th edition, Third Indian Reprint, 2003, Pearson Education Pvt.
Ltd., New Delhi.
5. Practical Inorganic Chemistry G. Pass and H. Sutcliff, Chapman and Hall Ltd (1968)
CHGT1.2: ORGANIC CHEMISTRYI

UNITI
Bonding in Organic Molecules:
Localized chemical bonding: Bond distances, bond angles, bond energies, bond polarity, dipole
moment and calculation of heat of reactions.
Delocalised chemical bonding: Conjugation, cross conjugation, steric inhibition of resonance,
hyperconjugation, tautomerism, valence tautomerism. Bonding in fullerenes.
Structure and reactivity: BrönstedLowry concept of organic acids, conjugate acids and bases,
pH, pKa values. Electronic, steric, and solvent effects on their strengths. General and specific
acid base catalysis, running scale of acidity. Lewis acids and bases. HSAB concept.
(12 Hours)
UNIT-II
Organic Reaction Mechanisms:
Classification of organic reactions: Meaning and importance of reaction mechanism.
Non-kinetic methods of Detrmination of Reaction Mechanism: Product identification, cross over

experiments, study of intermediates, isotopic labeling, kinetic isotope effects and stereochemical
studies.
Nucleophilic substitutions (Aliphatic): Mechanisms of SN2, SN1 (rearrangements in SN1

reactions) and SNi, SRN1 pathways. Effects of structure, leaving groups and ambident
nucleophiles.
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Elimination Reactions: E2, E1, E1CB pathways. Stereochemistry, product proportions in
dehydration of alcohols, alkyl halides (chiral and achiral), Hoffmann and Saytzeff rules.
Substitution v/s elimination and pyrolytic eliminations.
(12 Hours)
UNIT-III
Stereochemistry and Conformational Analysis:
Elements of symmetry and chirality, optical isomerism, optical activity, specific rotation.
molecules with one asymmetric center. Fischer, Wedge and 3D representations, DL and RS
systems indicating configuration. Ring compounds, molecules with two chiral centers: Fischer,
Saw-Horse, Newmann projections and their transformations.
Enantiomers, diastereomers, epimers, racemization, resolution. Stereochemical correlation.
Geometrical isomerism: EZ nomenclature, configuration of geometrical isomers and syn &
anti isomers.
Conformational analysis: Conformational study of n-Butane, ethylene, glycol, chlorohydrin.
(12 Hours)
UNIT-IV
Aromaticity:
Aromaticity and Huckel’s Rule: HMO theory, energy level diagrams, möbius systems, benzenoid
and non-benzenoid aromatic compounds. Tropones, tropolones, borazine and azulene.
Heterocyclic Systems: Systems of the type pyrrole, pyridines, pyrilium cation, ferrocene.
alternant and non-alternant hydrocarbons. Aromaticity of charged rings (38 membered), non
aromatic, anti-aromatic and homo aromatic systems.
Ring current as criteria for aromaticity. Annulenes and heteroannulenes [10-18].

(12 Hours)
Total 48 Hours
Books Recommended:
1. Organic ChemistryP. Y. Bruice, 7th Edition, Pearson Education Pvt. Ltd., New Delhi (2013).
2. Organic Chemistry S. H. Pine, McGraw-Hill, London (1987).
3. Mechanism and Structure in Organic Chemistry1965, by E.S. Gould.
4. Organic ChemistryR. T. Morrison and R.T. Boyd, Prentice Hall, New Delhi (1994).
5. Organic ChemistryT. W. Graham Solomons, 4th Edition, John Wiley and Sons (1988).
6. Organic ChemistryG. M. Loudon, 4th Edition, Oxford University Press, New York (2002).
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7. Organic Chemistry VolumeI, III. L. Finar, 6th Edition, ELBS London (2004).
8. Organic ChemistryF.A. Carey, 4th Edition, McGraw Hill (2000).
9. Advanced Organic Chemistry, Reactions, Mechanism and StructureJ. March, 3rd Edition,
Wiley Eastern Ltd. (2004).
10. StereochemistryConformation and MechanismP. S. Kalsi, WileyEastern Ltd, New Delhi
(1992).
11. Guidebook to Mechanism in Organic ChemistryP. Sykes. Orient Longman, London (2002).
12. AromaticityP. J. Garratt, McGraw Hill Book company (1971).
CHG(Pr)1.6 : Lab Course In Organic Chemistry

Preparation of the following organic compounds:
1. Benzoic acid and benzyl alcohol from benzaldehyde (Cannizarro reaction).

2. Cyclohexanone from cyclohexanol.
3. Reduction of p-nitrobenzaldehyde to p-nitrobenzylalcohol.
4. 2,4-Dinitrophenol from chlorobezene.
5. Benzil from benzaldehyde.
6. m-Nitroaniline from nitrobenzene.
7. m-Nitro benzoic acid from ethyl benzoate.
8. Benzanilide from benzophenone (Beckmann rearrangement).
9. p-Bromoaniline from acetanilide.
10. p-Nitroaniline from acetanilide.
Books Recommended:
1. Vogel’s Textbook of Practical Organic Chemistry RevisedB.S.Furniss, A. J. Hannaford,
P.W.G. Smith, A. R. Tatchell, 5th Edition, Addison Wesley Longman Limited, UK, 1997.
2. A Hand book of Organic Chemistryby H. T. Clarke.
3. A Laboratory Manual of Organic Chemistry by B. B. Dey and M. V. Govindachari.
4. Lab Experiments in Organic Chemistryby Arun Sethi, New Age International Ltd. New
Delhi. 2006.
i. Duration of examination : 04 hours

ii. Experiments : 35 marks
iii. Viva-Voce & Journal : 05 marks
iv. Internal assessment : 10 marks
Total : 50 marks
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CHGT-1.3: PHYSICAL CHEMISTRYI
UNITI
Quantum Mechanics:
Review of classical mechanics: Equation of motion for a particle, Newtonian, Lagrangian and
Hamiltonian equations of motion, elementary wave motion. Operators, eigen values and
expectation values, commuting operators, linear operator and hermitian operators. Solutions of
Schrödinger equations of a free particle, particle in a box problem: in one and three dimensions,
degeneracy, reflection and penetration of a particle in a one dimensional box of semi-infinite
barrier, a particle in a box of finite walls.
Rigid rotator, derivation of selection rules for transitions in rotating molecule, linear harmonic
oscillator, Hermite polynomials. Equation for the hydrogen atom in spherical polar coordinates
and an indication of the method of its solution, the quantum numbers and their significance.
Hydrogen-like atoms, properties of the Hatom wave functions. Electronic energy states of
Hatom. Many electron systems and the self consistent field method. Electronic configurations
in the periodic table. Pauli exclusion principle.
(12 Hours)
UNITII
Reaction Kinetics:
A critical account of collision and transition state theories.
Kinetics and mechanism: Steady state approximation and simple examples relating kinetics to
mechanism. Theories of Unimolecular reactions: RRKM theory. Isomerisation of methyl
isocyanide. Chain Reactions, examples of chain reactions, general aspects of chain reactions.
Chain-length, chain transfer reactions, chain inhibition, kinetics of branching chain reactions and
explosion limits.
(12 Hours)
UNITIII
Thermodynamics:
Thermodynamic criteria for spontaneous chemical changes. Systems at (i) constant volume and
temperature and (ii) constant pressure and temperature (derivation of dA ≤ 0 & dG ≤ 0).
Dependence of free energy on pressure and temperature. Standard free energies and their
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determination. Relation between free energy change and equilibrium constant. GibbsHelmholtz
equation and their different forms. The pressure dependence of free energy of nonideal gases
and fugacity. Standard state for non-ideal gas. Equilibrium constant for system of nonideal
gases. Lewis and Randall rule. Temperature dependence of free energy and equilibrium
constants.
Partial miscibility, activity and activity coefficients of components of solutions, partial molar
quantities and their determinations. GibbsDuhem equation and the calculation of activity of a
component in solutions. DuhemMargules equation. Ternary systems and phase diagram of
ternary systems.
(12 Hours)
UNITIV
Polymers:
Review on basic concepts of polymers and their classifications. Homopolymers, copolymers,

terpolymers, addition polymers and condensation polymers with examples. Comparision
between addition polymers and condensation polymers. Tacticity with examples of polystyrene
and PMMA. Elastomers, difference between elastomer and thermoplastic, approaches to increase
processability.
Techniques of freeradical polymerization: Bulk, solution, suspension, emulsion and

precipitation polymerization.
Reactions of vinyl polymers: Functional group reactions, ring-forming reactions and block &
graft copolymer formation. Crosslinking reactions: peroxide crosslinking, sulphur vulcanization,
radiation crosslinking, photo crosslinking, electron beam crosslinking and miscellaneous
crosslinking reactions. Polymer degradation: Chemical, thermal and radiation degradations.
(12 Hours)
Total: 48 Hours
Books Recommended:
1. Introduction to Quantum Chemistry by A. K. Chandra, Ed. 3, Tata McGraw Hill, New
Delhi, 1988.
2. Quantum Chemistry by R. K. Prasad, New Age International Publications, New Delhi,
1997.
3. Quantum Chemistry by Eyring, Walter and Kimball, John-Wiley, New York.
4. Physical Chemistry by G. M. Barrow, McGraw Hill, New York, 1996.
5. Fundamentals of Physical Chemistry by Maron and Lando.
6. Physical Chemistry by P. W. Atkins, ELBS, London, 1990 (Ed. 4).
7. Physical Chemistry by K. Vamulapalli, Prentice Hall of India Pvt. Ltd., New Delhi,
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1997.
8. Physical Chemistry by Daniels and Alberty, Wiley, New York.
9. Physical Chemistry Through Problems by S. K. Dogra and S Dogra, Wiley Eastern,
New Delhi.
10. A Text Book of Physical Chemistry by Samuel Glasstone, McMillan, London.
11. Atomic Structure and Chemical Bonding by Manas Chanda, Tata McGraw Hill
Publishing Co., New Delhi.
12. Chemical Kinetics by K. J. Laidler, Tata McGraw Hill Publishing Co., New Delhi.
13. Kinetics and Reaction Mechanisms by Frost and Pearson, Wiley, New York.
14. Polymer Chemistry: An Introduction, Malcolm P. Stevens, Oxford University Press,
1999.
15. Contemporary Polymer Chemistry, Harry R. Allcock and Frederick W. Lampe, Printice-
Hall, 1981.
16. Principles of Polymer Chemistry, P. Bahadur and N. V. Shastri, Narosa Publisher, 2002
17. Polymer Chemistry: Properties and Applications, Andrew Peacock and Allison Calhoun,
Hanser Publisher, 2006.
18. Text Book of Polymer Chemistry, Fred W. Billmeyer, Jr., Wiley Publisher, 1984.
19. Polymer Science, V. R. Gowariker, N. V. Viswanathan and Jayadev Sreedhar, New Age
International Publisher, 2001.
CHG(Pr)1.7: LAB COURSE IN PHYSICAL CHEMISTRY
1. General Information and Chemical mathematics: Calibration of glasswares, concentration

measures of solutionsconcept of normality, molarity, molality and mole fraction,
prepration of standard solution.
Treatment of Experimental data–Errors, type of errors, Accuracy and precision. Mean
deviation, standard deviation, significant figures, Methods of average and least squares.
2. Spectrophotometry: To obtain the absorption curve of KMnO4 solution on a colorimeter
and hence verify BeerLamberts law.
3. Potentiometery: Determination of the dissociation constant of dibasic acids (minimum
two acids and titration with NaOH)
4. Conductance: Simultaneous estimation of H2C2O4 and HCl in the mixture
conductometrically by titrating with NaOH.
5. Distribution law: Studying the distribution of benzoic acid between water and benzene
and hence determine the degree of association of benzoic acid in benzene.
6. Viscosity: Determination of viscosity average molecular weight of polystyrene in toluene
by Ubbelohde Viscometer
7. Thermochemistry: Determine the relative strength of CH3COOH and ClCH3COOH by
calorimetric method.
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8. Reaction Kinetics: Determination of activation parameters of the reaction of acid
hydrolysis of methyl acetate at two different temperatures.
9. Cryoscopy: Determination of cryoscopic constant of benzene and nitrobenzene
10. Refractometry: Analysis of a binary mixture (glycerol and water) by refractive indices
measurement.
Books Recommended:
1. Practical Physical Chemistry by A. M. James and F. E. Prichard, Longmans, London.

2. Experiments in Physical Chemistry by Shoemaker and Garland, McGraw Hill, New York.
3. Experiments in Physical Chemistry by Daniels, Alberty and Willams, McGraw Hill, New York.
4. Experimantal Physical Chemistry by W. G. Palmer, Cabridge University Press, London.
5. Advanced Physico-Chemical experiments by J. Rose. 6. Text Book of Physical Chemistry by S.
Glasstone, , McGraw Hill,London.
6. Text book of Quantitative Analysis by A. I. Vogel, ELBS, Harlow.
7. Advanced Practical Physical Chemistry by J. B. Yadav, Goel Publishing House.
8. Experimental Physical Chemistry by V. D. Athawale and Parul Mathur, New Age International
Publishers.
9. Advanced Physical Chemistry Experiments by Gurtu and Gurtu, Pragati Prakashan Educational
Publishers, 3rd Edition 2007.
i. Duration of examination: 04 hours
ii. Experiment : 35 marks
Total : 50 marks
CHGT1.4: ANALYTICAL CHEMISTRY
UNITI
Language of Analytical Chemistry, Data Treatment and Gravimetric Analysis:
Language of analytical chemistry: Definition of analysis, determination, measurement,

techniques and methods. Classification of analytical techniques. Selection of an analytical
method: Accuracy, precision, sensitivity, selectivity, robustness and ruggedness. Figures of merit
of analytical methods: Sensitivity, detection limit and linear dynamic range.
Errors and Treatment of analytical Data: Limitations of analytical methods–Errors: determinate

and indeterminate errors, minimization of errors. Statistical treatment of finite samples, measures
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of central tendency and variability, mean, median, range, standard deviation and variance.
Student’s t-test, confidence interval of mean. Testing for significance and comparison of two
means and two standard deviations. Comparison of an experimental mean and a true mean.
Criteria for the rejection of an observation, Qtest. External standard calibration, the least
squares methods, regression equation and correlation coefficient.
Gravimetric analysis: Mechansim of precipitation, factors influencing precipitation,

coprecipitation, postprecipitation and organic reagents used in gravimetry (oxime and dmg).
(12 Hours)
UNITII
Titrimetric Methods:
Titrimetric Analysis: Principles of titrimetric analysis. Classification of reactions in titrimetry.
Titrations based on acid-base reactions: Titration curves for strong acid and strong base, weak
acid and strong base and weak base and strong acid titrations. Titration curves, quantitative
applications, selecting and standardizing a titrant, inorganic analysis, alkalinity, acidity and
ammonium salts.
Complexometric titrations: Indicators for EDTA titrations, theory of common indicators, titration
methods employing EDTA, direct, back and displacement titrations, indirect determinations,
titration of mixtures using masking and demasking agents.
Redox Titrations: Balancing redox equations, calculation of the equilibrium constant of redox
reactions, titration curves, theory of redox indicators, calculation of standard potentials,
determination of chemical oxygen demand (COD) in natural and waste waters.
Precipitation titrations: Titration curves, titrants and standards, indicators for precipitation
titrations involving silver nitrate, the Volhard, the Mohr and the fajan’s methods
(12 Hours)
UNITIII
Separation MethodsI:
Fundamentals of chromatography: General description, definition, terms and parameters used in
chromatography, classification of chromatographic methods, criteria for selection of stationary
and mobile phase and nature of adsorbents.
Column chromatography: Theories, plate theory, rate theory, band broadening-eddy diffusion,
longitudinal diffusion and resistance to mass transfer, column efficiency, Van Deemter’s
equation and its modern version, interrelationships, capacity factor, selectivity factor, column
resolution, distribution constant and applications of conventional column chromatography,
advantages and limitations.
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Thin layer chromatography (TLC): Definition, mechanism, efficiency of TLC plates,
methodology, selection of stationary and mobile phases, development, spray reagents,
identification and detection, reproducibility of Rf values, qualitative and quantitative analysis.
High performance liquid chromatography (HPLC): Instrumentation, pumps, column packing,

characteristics of liquid chromatographic detectors, UV and fluorescence detectors, advantages
and applications.
(12 Hours)
UNITIV
Separation methods-II
Gas chromatography (GC): Principle, instrumentation, columns, study of detectors, thermal

conductivity, flame ionization and mass spectrometry, factors affecting separation, retention
volume, retention time and applications.
Ion exchange chromatography (IEC): Definition, principle, requirements for ion-exchange resin,
types of ion-exchange resins, resin properties-ion-exchange capacity and its determination, resin
selectivity and factors affecting the selectivity, applications of IEC in purification and recovery
processes.
Solvent extraction: Nernst partition law, efficiency and selectivity of extraction. Extraction
systems: Extraction of covalent neutral molecules, extraction of uncharged metal chelates and
synergic extraction, extraction of ion-association complexes-non chelated complexes and
chelated complexes. Use of salting out agents. Methods of extractionbatch and continuous
extractions. Applications (special emphasis on extraction of iron and copper).
(12 Hours)
Recommended Books:
1. Fundamental of Analytical Chemistry, D.A. Skoog, D.M. West, Holler and Crouch, 8 th
edition, Saunders College Publishing, New York (2005).
2. Analytical Chemistry, G.D. Christian, 6th edition, WileyIndia (2007).
3. Quantitative Analysis, R.A. Day and A.L. Underwood, 6th edition, PHI Learning Pvt Ltd.
New Delhi(2009).
4. Vogel’s Textbook of Quantitative Chemical Analysis, J. Mendham, R.C. Denney,
J.D.Barnes and M.J.K. Thomas, 6th edition, Third Indian Reprint, Pearson Education Pvt.
Ltd.(2007).
5. Analytical Chemistry Principles, John H. Kennedy, 2nd edition, Saunders College
Publishing, California(1990).
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CHG(Pr)1.8: Lab Course in Analytical Chemistry
I. Organic Chemistry Practical

Quantitative analysis
1. Titrimetric Estimation of amino acids.
2. Estimation of glucose by Bertrand’s method.
3. Estimation of keto group.
4. Iodine value of oil (Chloramine - T method)
5. Estimation of Nitro group by reduction using SnCl2.
Qualitative Analysis
Separation of binary mixture of organic compounds using ether and identification of
separated compounds by systematic qualitative organic analysis.
Please Note: 1) Individual organic compounds are to be given after the candidate reports the
nature of the mixture. 2) Ether insoluble acids and ether insoluble Neutral organic compounds
may be given. 3) Low boiling liquids and Amino acids need not be given.
The following mixtures may be given.
1. Acid + Base
2. Acid + Neutral
3. Base + Neutral
4. Phenol + Acid
5. Base + Phenol
II. Physical Chemistry Practicals
1. Determination of molecular radius of glycerol molecule by viscosity method.
2. Estimation of metal ions of ferric-thiocyante and cupric-ammonia complexes by
spectrophotometrically.
3. Determination of relative strength of acids (HCl and H2SO4) by studying the hydrolysis
of methyl actetate.
4. Determination of dissociation constants of weak monobasic acids potentiometrically by
titrating against NaOH.
5. Comparison of strengths of chloroacetic acid and acetic acid using conductometric
method.
6. Determine the dissociation constant of acetic acid pH-metrically by titrating against
NaOH.
18 | P a g e
Books Recommended:
1. Practical Physical Chemistry by A. M. James and F. E. Prichard, Longmans, London.
Experiments in Physical Chemistry by Daniels, Alberty and Willams, McGraw Hill, New York.
3. Experimantal Physical Chemistry by W. G. Palmer, Cabridge University Press, London.
4. Advanced Physico-Chemical experiments by J. Rose. 6. Text Book of Physical Chemistry by S.
5. Glasstone, , McGraw Hill,London.
6. Text book of Quantitative Analysis by A. I. Vogel, ELBS, Harlow.
7. Advanced Practical Physical Chemistry by J. B. Yadav, Goel Publishing House.
Publishers.
Publishers, 3rd Edition 2007.
Total : 50 marks
SEMESTER II
CHGT2.1: INORGANIC CHEMISTRY-II
UNITI
Chemistry of Non-Transition Elements:
Alkali and alkaline earth metal complexes of crown ethers, cryptands and calixarenes and their
biological importance.
Synthesis, properties and structures of boron, carbon and silicon compounds: Chemistry of
higher boranes, classification, structures and MO description of bonding, framework electron
counting, Wade’s rules, chemistry of B5H9, B10H14 and BnHn2, boron nitride, borazines,
carboranes, metalloboranes, metallocarboranes; silicates, silicones, graphite, graphene, carbon
nanotubes and zeolites.
Hydrogen bonding and its influence on properties.

(12 Hours)
19 | P a g e
UNITII
Chemistry of Main Group Elements:
Nitrogen, phosphorous and sulphur compounds: Hydrides, oxides and oxy acids of nitrogen,
phosphorous, sulphur and halogens. Phosphazines, phosphazene polymers, sulphurnitrogen
compounds: Binary sulphur nitrides: S4N4, S2N2 and (SN)x. PO and PS cage compounds.
Chemistry of halogens and xenon: Interhalogens, psuedohalogens, polyhalide ions, oxyhalogen

species. Xenon oxides and fluorides.
(12 Hours)
UNITIII
Symmetry and Group Theory:
Molecular symmetry, representation of symmetry operation as matrices. Definition of groups, set

of symmetry operations of molecules satisfying the condition of point groups. Representation,
basis of representation, reducible and irreducible representation. The great orthogonality
theorem, character tables. The direct product. Applications of group theory: Molecular
vibrations; molecular vibration in symmetrical AB2. Hybridisation (tetrahedral and trigonal
planar geometries)
(12 Hours)
UNITIV
Organometallic Chemistry:
Organometallic compounds: Introduction, classification of organometallic compounds by bond

type, nomenclature, classification of ligands σ and π ligands, hapticity of ligands, 18 and 16
electron rules, electron counting schemes. Ferrocene and ruthenocene: Preparation, structure and
bonding. Complexes containing alkene and alkyne ligands: Preparation, structure and bonding.
Carbene (Fischer and Schrock type) complexes: Synthesis, structure and bonding. The isolobal
principles.
Use of organometallic reagents in hydrogenation, hydroformylation, isomerisation and

polymerization reactions.
(12 Hours)
Recommended Books:
1. Inorganic ChemistryPrinciples of Structure and Reactivity, 4thEdnJ. E. Huheey, E.A.

Keiter, R. L. Keiter and O.K. Medhi. Pearson Education (2009).
2. Shriver & Atkins’ Inorganic Chemistry, 5th EdnP. Atkins, Tina Overton, J. Rourke, Mark
Weller and F.Armstrong.Oxford University Press (2010)
20 | P a g e
3. Inorganic Chemistry, 2nd Edn. Catherine E. Housecroft and A.G. Sharpe, Pearson Prentice
Hall (2005)
4. Concise Inorganic ChemistryJ. D. Lee, 5th Edn, New Age International (1996).
5. Chemical Applications of Group Theory, 2nd Edn-F. A. Cotton, Wiley Eastern Ltd ( ).
6. Symmetry and Spectroscopy of MoleculesK. Veera Reddy, New Age International, (2011).
7. Group Theory in ChemistryM. S. Gopinathanan and V. Ramakrishnan, Vishal Publishing
Co. (2007)
8. Organometallic ChemistryA unified Approach, R.C. Mehrotra and A. Singh, 2nd Edn. New
Age International (2011).
9. F.A.Cotton and G.Wilkinson : Advanced Inorganic Chemistry, Wiley, 1991.
10. Basic Organometallic Chemistry– B D Gupta and A J Elias, Universities Press (2013)
CHG(Pr)2.4: Lab Course in Inorganic Chemistry
1. Semimicro qualitative inorganic analysis of a mixture containing three cations (including one
less common cation such as W, Mo, Ti, Zr, Ce, V and Li) and two anions (one of them may or
may not be interfering anion such as PO43, BO33, C2O42, F and CH3COO).
2. Separation and determination of Zn and Mg on an anion exchanger.
3. Demonstration experiment: Determination of iron as the 8hydroxy quinolate by solvent

extraction.

Total : 50 marks
Recommended Books:
1. Vogel’s Text Book of Quantitative Chemical Analysis(5th Ed), G.H.Jeffrey, J.Bassette,

J.Mendham and R.C.Denny, Longman, 1999.
2. Vogel’s Qualitative Inorganic Analysis(7th Ed), G.Svehla, Longman ( 2001)
21 | P a g e
CHGT2.2: ORGANIC CHEMISTRYII
UNITI
Reaction Mechanism:
Aliphatic electrophillic substitutions: SE2, SE1 and SEi mechanisms. Reactions involving double
bond shifts, -halogenation of carbonyl compounds, nitrosation at carbon bearing active
hydrogen.
Aromatic electrophillic substitutions: Mechanisms of aromatic, nitration, sulphonation,

halogenation, isotope effects, energy profile diagrams. Kinetic and thermodynamic control,
sulphonation, Hammond's Postulate, o/p ratio, ipsosubstitution, Vilsmeir Haack and Fries
rearrangement.
Aromatic nucleophilic substitutions: SNAr, SN1 and aryne pathways. Meisenheimer complexes,
mechanism and synthetic applications of vicarious nucleophilic substitution (VNS), Von-Richter,
Goldberg, Bucherer, Shiemann reactions and Smiles rearrangement.
(12 Hours)
UNITII
Advanced Stereochemistry:
Prochirality: Homotopic, enantiotopic and diastereotopic atoms, groups and faces.
Stereochemical descriptors: Application to reduction of carbonyl compounds, cyanohydrin

formation, addition of water to alkenes.
Optical activity due to molecular dissymmetry: Allenes, spiranes, biphenyls, atropisomerism,

molecular crowding.
Conformational analysis of cyclohexane, mono substituted and disubstituted (1,2, 1,3, 1,4)
cyclohexanes, Chirality of cyclohexanes.
(12 Hours)
UNITIII
Carbohydrates:
Monosaccharides: Conformational representation of monosaccharides and their transformations.

Determination of configuration of the monosaccharides, mechanism of mutarotationbase
catalyzed isomerisation of aldoses and ketoses. Epimerisation, anomeric effect, glycosides, ether
and ester derivatives of carbohydrates. Acetone, amino and deoxysugars. Oxidation and
reduction reactions of carbohydrates.
22 | P a g e
Disaccharides: Structure elucidation of maltose, lactose, sucrose.
Polysaccharides: Structure and degradation of starch, cellulose and glycogen.
(12 Hours)
UNITIV
Chemistry of heterocycles: Nomenclature of heterocyclic compounds (including fused

heterocycles).
Synthesis and chemical reactions of indole, quinoline, isoquinoline, thiazole, imidazole,

benzimidazole, coumarin, flavones.
(12 Hours)
Total 48 Hours
Books Recommended:
1. Advanced Organic Chemistry part A and BF. A. Carey and R. J. Sundberg, 4th Edition,
Plenum Publishers (2000).
2. Advanced Organic Chemistry, Reactions, Mechanism and StructureJ March, 3rd Edition,
Wiley Eastern Ltd. (2004).
3. Guide Book to Mechanism in Organic chemistryPeter Sykes Oriant- Longman (1985).
4. Stereochemistry of Carbon CompoundsEliel, Tata McGraw Hill, New Delhi (1976).
5. Stereochemistry of Organic Compounds, Principles and Applications – D. Nasipuri, Wiley
Eastern Ltd (1992).
6. Organic Chemistry VolI, II, IIIS. M. Mukherji, S. P. Singh and R. P. Kapoor, New Age
International Ltd, New Delhi (2000).
7. Organic Chemistry VolumeI, II I. L. Finar, 6th Edition, ELBS London (2004).
8. Chemistry of CarbohydratesG. C. Percival.
9. Carbohydrates Chemistry and Biochemistry –Pigman and Harton.
10. Heterocyclic ChemistryT. L. Gilchrist, 3rd Edition, Pearson Education Delhi, (2005).
11. Heterocyclic Chemistry J.A. Joule and G.F. Smith, 2nd Edition, Van Nostrand London
(1978).
12. Heterocyclic ChemistryR. K. Bansal, 3rd Edition, NewAge Interantional, New Delhi,
2004.
13. https://profiles.uonbi.ac.ke/sderese/files/upc_213nomenclature_of_heterocyclic_compounds
_0.pdf
CHG(Pr) 2.5 : LAB COURSE IN ORGANIC CHEMISTRY
23 | P a g e
1. Quantitative Estimation of the following Organic compounds: (i) Acid (ii)Acid + Amide (iii)
Acid + Ester (iv) Molecular weight determination by base hydrochloride method (v) Phenol
(Bromometric method).
2. Preparations of derivatives of heterocycles like coumarins, quinolines, benzimidazoles,
benzoxazines, pyrazoles by convention, microwave and by sonication.
3. Preparations based on functional group reactions of organic compounds like aldehydes,
ketones, esters, phenols etc.
Note: Any two of the above experiments will be prescribed for the examination.
Scheme of Examination

ii. Experiments : 35 marks
Total : 50 marks
Books Recommended:
1. Vogel’s Textbook of Practical Organic Chemistry RevisedB.S. Furniss, A.J. Hannaford,
P.W.G. Smith, A.R. Tatchell, 5th Edition, Addison Wesley Longman Limited, UK, 1997.
2. A Hand book of Organic Chemistry –H.T. Clarke.
3. A Laboratory Manual of Organic ChemistryB. B. Dey and M.V. Govindachari.
4. Lab Experiments in Organic Chemistry –Arun. Sethi, New Age International Ltd. New Delhi.
2006.
5. Experimental Organic ChemistryL. M. Harwood, and C. J. Moody, Blackwell Scientfic,
London, 1989.
6. Practical Organic ChemistryW. Kemp, McGraw Hill, London, 1967.
CHGT2.3: PHYSICAL CHEMISTRYII

UNITI
Microwave Spectroscopy and Xray Diffraction:
Microwave spectroscopy: Gaseous microwave spectra and rotational transitions: Study of

inversion of ammonia and hindered rotations in molecules. Instrumentation. Stark effect in
molecular spectra, first and second order Stark effects.
24 | P a g e
Xray diffraction: Origin and production of Xrays, interaction of Xrays with matter:
Absorption, scattering and diffraction. Reciprocal lattice: Brag’s law in reciprocal space.
Instrumentation: Sources, filters, monochromatic detectors. Crystal structure: Unit cell, lattices,
planes and miller indices. Debye-Scherrer powder methods and Weissenberg camera. Numerical
problems.
(12 Hours)
UNITII
Reaction Kinetics:
Kinetics in Solution: Effect of solvent, pressure and ionic strength for ion-ion, ion-neutral
molecule type reactions and cage effects.
Potential energy surfaces, methods employed in the construct of potential surfaces, calculating
reactions.
Fast Reactions: Techniques for fast reactions, flow methods, stopped flow technique, relaxation
methods and flash photolysis. Numerical problems.
(12 Hours)
UNITIII
Electrochemistry:
Introduction to electrochemistry, DebyeHuckel and Bjerrum models and the corresponding
theoretical expression for activity coefficient and Debye-Huckel-Onsagar theory of conductance
of strong electrolytes.
Electrochemistry of Solution: Activity of ions in solution, solvation number and their

determination, ion-solvent interactions, ion-ion interactions and free energy of ions in solution
and triple ion formation, conductance minima and free energy of ions in solution. Born model
for calculating the free energy of ion-solvent interaction and its modifications. The enthalpy and
entropy of ion-solvent interaction. Electrical double layer: Electrocapilarity, Lippman equation
(surface excess), theories of electrical double layer: HelmholtzPerrin, Gouy-Chapman and Stern
theories. Effect of ions on zeta potential. Over potentials, exchange current density, derivation of
Butler-volmer equation and Tafel plot.
(12 Hours)
25 | P a g e
UNIT- IV
Polymer chemistry:
Transitions in polymers: Definition of glass transition temperature (Tg) and flow temperature
(Tf ) and melting temperature (Tm), thermal behaviour of amorphous and crystalline polymers,
factors affecting the Tg. Plasticizers, properties and their effect on Tg of PVC and
diethylhexylsuccinate, efficiency of plasticizers, comparison of Tg and Tm. Tg of copolymers and
polymer blends, relation between Tg and Tm.
Polymer molecular weight: Number average and weight average molecular weights,
polydispersity and molecular weight distribution in polymers. Numerical problems on
determination of molecular weights.
Kinetics of polymerization: Kinetics of free-radical addition polymerization, cationic

polymerization, anionic polymerization, copolymerization and determination of reactivity ratios.
Polymer synthesis: Ziegler-Natta polymerization (isotactic and syndiotactic) and its limitations.
Metallocene catalysis polymerization (isotactic). Metathesis polymerization: Acyclic diene
metathesis polymerization (ADMET) and ring opening metathesis polymerization (ROMP).
Group transfer polymerization (GTP) and advantages of GTP.
(12 Hours)
Total 48 Hours
Books Recommended
1. Fundamentals of Molecular Spectroscopy by C. N. Banwell, Tata McGraw Hill

1. Publishing Co., New Delhi.
2. An introduction to Molecular Spectroscopy by G. M. Barrow, McGraw Hill, New York.
3. Molecualr Spectra and Molecular Structure:I Spectra of Diatomic Molecules by G.
4. Herzberg, Van Nostrand, Princeton.
5. Physical Chemistry by P. W. Atkins, ELBS, London.
6. Physical Chemistry by G. M. Barrow, McGraw Hill, New York.
7. Atomic and Molecular Spectroscopy by M. C. Gupta, New Age International Publishers,
New Delhi.
10. Chemical Kinetics by K. J. Laidler, McGraw Hill, 1950.
11. Kinetics and mechanism of chemical transformations by J. Rajaraman and J. Kuriacose,
McMillan.
12. Theory of rate processes by S. Glasstone, K. J. Laidler and H. Eyring, McGraw- Hill, 1941.
26 | P a g e
13. Thoeries of Chemical recation Rates by K. J. Laidler, McGraw-Hill, 1969.
14. Techniques of Organic by Weissberger(ed.), Interscience, Vol.VIII, 1963,
15. Kinetics of Chemical Changes in Solution by E. S. Amis, MacMillan, 1948
16. The Foundations of Chemical Kinetics by S. W. Benson, MacGraw-Hill, 1960.
17. An Introduction to Electrochemistry by S. Glasstone, Van Nostrand, London
18. A Text book of Electrochemistry by G.F.A. Kortum and J.O.M. Bockris, Elsevier, New
York.
19. Modern Electrochemistry by J.O.M. Bockris and A.K.N. Reddy Vol. I and Vol. II,
Butterworths, London.
20. Polymer Chemistry: An Introduction, Malcolm P. Stevens, Oxford University Press, 1999.
21. Contemporary Polymer Chemistry, Harry R. Allcock and Frederick W. Lampe, Printice-
Hall, 1981.
22. Principles of Polymer Chemistry, P. Bahadur and N. V. Shastri, Narosa Publisher, 2002
23. Polymer Chemistry: Properties and Applications, Andrew Peacock and Allison Calhoun,
Hanser Publisher, 2006.
24. Text Book of Polymer Chemistry, Fred W. Billmeyer, Jr., Wiley Publisher, 1984.
25. Polymer Science, V. R. Gowariker, N. V. Viswanathan and Jayadev Sreedhar, New Age
International Publisher, 2001.
CHG(Pr)2.6: LAB COURSE IN PHYSICAL CHEMISTRY
1. Solubility: Determine the heat of solution of a solute (e.g oxalic acid or benzoic acid) by
solubility method.
2. Coulometric titration: Titration of I2 against Na2S2O3.
3. Cryoscopy: Determination of the degree of dissociation of a given strong electrolyte and the
determination of the number of ions present in the solute using cryoscopy method.
4. Spectrophotometry: To obtain the absorption spectra of coloured complexes (Ferric-
thiocyante and Cupricammonia complexes) and hence verify the BeerLambert’s law and
estimation of metal ions in solution by spectrophotometry.
5. Conductance: (i) Determination of equivalent conductance of a weak electrolyte at different
concentrations and the applicability of Ostwald’s law. (ii) Determination of equivalent
conductance of a weak electrolyte from Kohlrausch’s law.
6. Potentiometry: Potentiometric determination of formal redox potential of Fe2+/Fe3+ and
Ce4+/ Ce3+ or Cr6+/ Cr3+ couples by titrating Fe2+ solution with Ce4+ or Cr6+.
7. Reaction Kinetics: Investigation of autocatalytic reaction between potassium permanganate
and oxalic acid in the presence of H2SO4.
8. Viscosity: Determination of limiting viscosity number (Staudinger index) of polystyrene.
9. pH metry: Titration of acetic acid against NaOH and hence determine the acid dissociation
constant (Ka).
27 | P a g e
Books Recommended:
1. Findlay’s Practical Physical Chemistry, 9th edition, revised by B. P. Levitt, Longman, London.
2. Practical Physical Chemistry by A. M. James and F. E. Prichard, Longman, London.
4. Experiments in Physical Chemistry by Daniels, Alberty and Willams McGraw Hill, New York.
5. Laboratory Physical Chemistry by Oelke/M.A.C.T.L.A.C.
6. Experimental Physical Chemistry by W. G. Palmer, C.U.P., London.
7. Advanced Physico-Chemical Experiments by J. Rose.
8. Text Book of Physical Chemistry by S. Glasstone, Macmillon and Co., London.
9. Text Book of Quantitative Analysis by A. I. Vogel, ELBS, Harlow.
10. Advanced Practical Physical Chemistry by J. B. Yadav. Goel Publishing House.
Publishers.
Publishers, 3rd Edition, 2007.
Total : 50 marks
III SEMESTER
CHGT3.1: INORGANIC CHEMISTRY
UNITI
Spectral and Magnetic properties of complexes:
Term symbols for dn ions, spectroscopic ground states, selection rules, nature of spectral bands-
band shapes, band intensities, band widths, effect of spin-orbit coupling, Orgel diagrams,
Tanabe-Sugano diagrams, Racah parameters, interpretation of spectra of octahedral, distorted
octahedral, tetrahedral and square planar complexes, calculation of nephelauxetic parameter,
charge transfer bands, intervalence charge-transfer bands.
Type of magnetic behaviour, classical magnetism, orbital contribution, orbital contribution

reduction factor, spin orbit coupling, measurement of magnetic susceptibility–Gouy and Faraday
methods, diamagnetic corrections, magnetically non-dilute compounds- ferro, antiferro and ferri
magnetic, spin cross-over systems, correlation of magnetic and structural properties
(12 Hours)
28 | P a g e
UNITII
Reaction Mechanisms in Transition Metal Complexes and Bioinorganic Chemistry:
Energy profile of a reaction, inert and labile complexes, kinetics of octahedral substitution and
mechanistic aspects. Acid hydrolysis, factors affecting acid hydrolysis, base hydrolysis,
conjugate base mechanism and evidences in its favour. Anation reactions, Substitution reactions
in square planar complexes, trans effect, mechanisms of substitution. Electron transfer reactions-
inner sphere and outer sphere reactions, complimentary and noncomplimentary reactions.
Bioinorganic Chemistry: Metal ions in biological systems-essential and trace metals, Transport
and storage of dioxygen haemoglobin, myoglobin, hemerythrin and hemocyanins, Electron
transfer proteins- cytochromes, iron-sulphur proteins. Metalloproteins as enzymes–carboxy
peptidase, catalases, peroxidases, cytochrome P450, superoxide dismutase, copper oxidases,
vitamin B12 coenzyme, chlorophyll and its role in photosynthesis, photosystemsI & II, nitrogen
fixation and metal complexes in medicine.
(12 Hours)
UNIT–III
Applications of I.R. spectroscopy in Inorganic Compounds
Infrared spectra of simple molecules and coordination compounds, changes in infrared spectra of
donor molecules upon coordination (N,Ndimethylacetamide, urea, DMSO, pyridine Noxide,
ammine, cyano, cyanato and thiocyanato complexes), mono and multinuclear carbonyl
complexes, nitosyls, phosphine and arsine complexes. Change in spectra accompanying change
in symmetry upon coordination (NO3, SO42, NO2, and ClO4), hydrogen bonding,
instrumentation including FTIR.
(12 Hours)
UNITIV
Electron Paramagnetic Resonance (EPR) Spectroscopy:
Basic principles, Selection rules, intensity, width, position of spectral line, multiplet structure of
EPR spectra, hyperfine interaction, spin-orbit coupling, zerofield splitting and Kramer’s
degeneracy, rules for interpreting spectra, factros affecting the magnitude of values.
Instrumentation. Applications to the study of free radicals, Coordination compounds, biological
studies, rate of electron exchange reactions.
29 | P a g e
Mössbauer Spectroscopy:
Introduction, Principles, conditions for Mössbauer spectroscopy, parameters from Mossbauer

spectra, isomer shifts, electric quadrupole interaction, magnetic interactions, Mossbauer
spectrometer, applications, Fe3(CO)12, Prussion blue, oxyhemerythrin, hexacyanoferrates,
nitropruside, tin halides.
Nuclear Quadrupole Resonance (NQR) SpectroscopyQuadrupole nuclei, quadrapole

movement, electric field gradient, the NQR experiment, structural information from NQR
spectra.
(12 Hours)
Total :48 Hours
Books Recommended:
1. Electronic absorption Spectroscopy and Related Techniques–D. N. Satyanarayana, OUP,

2001.
2. Inorganic Reaction Mechanisms-F. Basolo and R. G. Pearson, Wiley Eastern, 1979.
3. W.W.Porterfield: Inorganic chemistry–A Unified Approach, Elsevier, 2005.
4. Elements of Magnetochemistry–R. L. Dutta and A Syamal : Affiliated East-West, 1993.
5. Inorganic Chemistry(4th edn) –J. E Huheey, R. L. Keiter and A. L. Keiter, Addison
Wesley, 2000.
6. Inorganic Chemistry of Biological Processes, (2nd edn.) –M. N. Hughes, Wiley, 1988.
7. Bioinorganic Chemistry–I. Bertini. H. B. Gray, S. J. Lippard and J. S. Valentine:, Viva
Books, 1998.
8. Bioinorganic Chemistry–A.K. Das, Books and Allied (P) Ltd, 2007
9. Principles of Bioniorganic Chemistry–S. J. Lippard and J. M. Berga. Panima Publishing
Corporation.
10. Fundamentals of Molecular Spectroscopy–C. N. Banwell.
11. Physical Methods in Chemistry–R .S. Drago, Saunder college.
12. Structural Methods in Inorganic Chemistry–E. A. Ebsworth, D. W. H. Ranbin and
S.Cradock, ELBS.
13. Infrared Spectra of Inorganic and Coordination Compounds, K. Nakamoto.
14. Infrared Spectroscopy–C.N.R. Rao.
15. Electron Absorption Spectroscopy and Selected Techniques–D. N. Satyanarayana,
University Prof. India Ltd. Hyderabad.
16. Introduction to Spectroscopy-Pavia, Lampman and Kriz.
30 | P a g e
CHG(Pr)3.5: Lab Course In Inorganic Chemistry
I. Preparation of the following complexes:
1. Copper-glycine complex : cis-and trans forms.

2. Co(DMG)2 model for Vit-B12 and reaction
3. Potassium trisoxalatoferrate(III)
4. tris(acetylacetonate)manganese(III)
5. hexaammine/pentaammine chlorido cobalt (III) chloride.
6. nitro- and nitrito-complexes.(examples for linkage isomers)
7. Tris(thiourea) copper(I) sulphate monohydrate
8. Seperation of optical isomers of cis[Co(en)2Cl2]Cl.
II. Characterisation
1. Metal ion/anion determination in the above complexes

1. Interpretation of electronic, IR and NMR spectra

ii. Interpretation of given spectra :10 marks
iii. Analysis of a complex : 25 marks
iv. Viva voce and Jounral : 05 marks
v. Internal Assessment :10 Marks
Total : 50 marks
Books recommended:
1. Vogel’s Text Book of Quantitative Inorganic Analysis–J. Basett, R. C. Denney, H.
2. Jeffery and J. Mendham, Longmans, Green and company Ltd.
2. Practical Inorganic Chemistry–G. Pass and H. Sutcliff, Chapman and Hall Ltd.(1968)
3. General Chemistry Experiments-A. J. Elias, University Press.
4. Computers and their applications to Chemistry, Ramesh Kumari, Narosa
31 | P a g e
Total : 50 marks
CHGT–3.2: ORGANIC CHEMISTRY Paper II
UNIT–I
Reaction Mechanism: Nucleophilic substitution at allylic and trigonal carbon atom.
Neighbouring group participation, participation of σ, π, cyclopropane and aromatic rings in

nucleophilic substitution reaction. Addition reactions: electrophilic addition across alkenes, cis-
trans alkenes, dienes.
Stereochemistry: Stereoselectivity in organic synthesis, stereospecific and stereoselective

reaction, principle of stereoselectivity, stereoselectivity in addition, elimination, substitution
reaction. Asymmetric synthesis, enantioselective and diastereoselectivity in acyclic system,
addition of nucleohphiles to carbonyl group, correalation of configuration, Crams rule and
Prelogs rule for diastereselection.
(12 Hours)
UNIT–II
UV and IR Spectroscopy:
Electronic Spectroscopy: Introduction. Energy considerations. Experimental methods. Beer-

Lambert’s law. UV spectral study of unsaturated carbonyl and aromatic compounds. Steric
effects, charge transfer bands.
Vibrational Spectroscopy: Introduction and Experimental methods. Units, Notation and

Regions. Fundamental vibrations, overtones, Group frequencies, factors affecting group
frequencies. Mechanical coupling, Fermi resonance, Applications of IR in the study of H–
bonding, Alkanes, Alkenes, Alkynes, Aromatic compounds, Aldehydes, Ketones, Alcohols,
Thiols, Acids, Acid chlorides, Amides, Amines, Esters, halides, nitro compounds, etc.
(12 Hours)
UNIT–III
32 | P a g e
Nuclear Magnetic Resonance:
1
H NMR: Magnetic properties of nuclei, shifts of different types of organic compounds
empirical rules, spin-spin coupling, geminal–vicinal coupling–relative intensities, Long range
coupling–spin decoupling, equivalence of protons–chemical and magnetic equivalence, spin–
systems Karplus equation–curve, first order and second order patterns, lanthanide shift reagents,
exchange phenomena. NOE.
13
C NMR: Broad band and off resonance coupling methods of detection. 13C Chemical shifts of
different classes of organic compounds–alkanes, alkyl halides, alkenes, alcohols, ethers, carbonyl
compounds and aromatic compounds.
(12 Hours)
UNIT–IV
Mass Spectrometry and Composite Problems:
Instrumentation and theoretical principles, determination of empirical formula. Fragmentation:

Principles, odd and EE ions, molecular ion and base peak, nitrogen rule, metastable ions. Isotope
effects in chloro and bromo compounds. Stevenson rule. Fragmentation of: i) normal and
branched alkanes. ii) alkenes. iii) benzene and its derivatives. iv) alcohols. v) aldehydes. vi)
ketones. vii) acids. viii) esters. ix) ethers. x) amines. xi) nitro compounds. xii) halo compounds.
McLafferty rearrangement.
Composite problems: Applications of UV, IR, NMR and Mass methods and chemical reactions
in structure elucidation of organic compounds.
(12 Hours)
Total: 48 Hours
Books Recommended:
1. Stereochemistry of Organic compounds –Eliel, Tata McGraw Hill (2000).

2. Stereochemistry, Conformation and Mechanism –P.S. Kalsi, 6th Edition, New Age
International Ltd. (2006).
3. Stereochemistry of Organic Compounds, Principles and Applications – D. Nasipuri, Wiley
Eastern Ltd. (1992).
4. Advanced Organic Chemistry part A and B –F.A. Carey and R.J. Sundberg, 4th Edition,
Plenum Publishers, (2000).
5. Advanced Organic Chemistry, Reactions, Mechanism and Structure – J March, 6th
6. Edition, Wiley Eastern Ltd. (2007).
7. Mechanism and Theory in Organic Chemistry –T.A.Lowry and K.S. Richardson, 3rd
Edition, Addison-Wesley, UK (1998).
33 | P a g e
8. Organic Chemistry Volume-I, II and III –S.M.Mukherji, S.P.Singh and R.P. Kapoor, New
Age International Ltd (2000).
9. Organic Reaction Mechanism – by R. K. Bansal, 3rd Edition, Tata McGraw Hill (2006).
10. Mechanism and Theory in Organic Chemicals –T.H. Lowry and K.S. Richardson, AWL,
UK, 1998.
11. Advanced Organic Chemistry–R. Buckner, HAP Publishers, Sandiego, USA (2002).
12. Reactive Intermediates in Organic Chemistry – N. S. Isaacs, John Wiley and Sons, 1974.
13. Advanced Organic Chemistry part A and B –F.A. Carey and R.J. Sundberg, 4th Edition,
Plenum Publishers, (2000).
14. Fundamentals of Molecular Spectroscopy by C. N. Banwell, Tata McGraw Hill
15. Publishing Co., New Delhi.
16. An introduction to Molecular Spectroscopy by G. M. Barrow, McGraw Hill, New
York.
17. Molecualr Spectra and Molecular Structure:I Spectra of Diatomic Molecules by G.
Herzberg, Van Nostrand, Princeton.
18. Introduction to Spectroscopy, Donald L. Pavia, Gary M. Lampman, and George S. Kriz,
Cenage Learning, USA, (2015).
CHG(Pr)–3.6: Lab Course In Organic Chemistry
Identification of the Nature, Bulk separation, Purification and Qualitative analysis (using
ether) of the Binary mixture of the following classes: Acids, Bases, Phenols and Neutral
compounds (without derivatives).
Total : 50 marks
Books Recommended:
1. Vogel’s Textbook of Practical Organic Chemistry Revised by B.S. Furniss, A.J.

2. Hannaford, P.W.G. Smith, A.R. Tatchell, 5th Edition, Addison Wesley Longman
34 | P a g e
3. Limited, UK, 1997.
4. A Hand book of Organic Chemistry–by H.T.Clarke.
5. A Laboratory Manual of Organic Chemistry by B.B.Dey and M.V. Govindachari.
6. Lab Experiments in Organic Chemistry–by Arun. Sethi, New Age International
7. Ltd. New Delhi. 2006.
Duration of examination : 04 hours

Experiments : 35 marks
Journal and Viva : 05 marks
Internal Assessment : 10 marks
Total : 50 marks
CHGT–3.3: PHYSICAL CHEMISTRY:
UNIT–I
Quantum Mechanics:
Equation for hydrogen atom and its solutions, separation of variables, the phi, theta and radial
equations, the problems of spherical symmetry.
Approximate methods in quantum mechanics: Variation method and variation theorem, linear
variation functions, secular equations and secular determinants. Application of variation method
to hydrogen molecule ion, hydrogen molecule and normal helium atom.
Perturbation theory (first order and non-degenerate), application of perturbation theory to the
helium atom.
(12 Hours)
UNIT–II
Atomic Structure and Atomic Spectra:
A summary of the hydrogen spectrum. Alkali spectra and alkali like spectra, spark spectra and
arc spectra. Moseley lines.
Helium and alkaline earth spectra. Multiplet structure of line spectra. Doublet structure of alkali
spectra and compound doublets, triplets and singlets of alkaline earths and helium, prohibition of
intercombinations. Multiplicities and term symbols.
Space quantization: Zeeman effect, normal and anomalous Zeeman effects, Paschen–Back effect,
Stark effect.
(12 Hours)
UNIT–III
Symmetry Properties of Molecules and Group Theory:
35 | P a g e
Introduction to symmetry, molecular symmetry, symmetry elements, symmetry operations and
matrix method in symmetry. Molecular point groups: point groups identification of point groups,
construction of group multiplication tables, symmetry species and point group character tables.
Reducible and irreducible representations, properties of irreducible representation, Mulliken

symbolism rules for irreducible representation, Structure of character tables, the standard
reduction formula and the great orthogonality theorem. Normal mode analysis: number of
normal modes of vibrational symmetry types, infrared and Raman activity, Rule of mutual
exclusion.
(12 Hours)
UNIT–IV
Diffraction Studies:
X-ray diffraction: Reciprocal lattice, indexing of single crystal rotation photographs,

determination of molecular parameters, the structure factor calculations, Fourier series and the
phase problems. Refinements of Fourier procedures.
Neutron diffraction: Neutron diffraction and differences from X–ray diffraction.
Electron diffraction: Theoretical principles, structure analysis: Visual comparison of intensities,

radial distribution function and its refinements. The rotating sector method.
(12 Hours)
Total 48 Hours
Books Recommended
1. Quantum MechaincsL.T.Schiff, PrenticeHall.
2. Quantum ChemistryH. Eyring, J. Walter and G. E. Kimball, John Wiley.
3. Quantum MechanicsAn IntroductionH. L. Strauss, Prentice Hall of India.
4. Quantum MechanicsL. Pauling and E.B.Wilson, McGraw Hill.
5. Contemporary Quantum ChemistryJ. Goodisman, Plenum/Rosetta.
6. Quantum ChemistryK. S. Pitzer, Prentice-Hall
7. Introductory Quantum Mechanics-Valdimir Rojanstry.
8. Quantum ChemistryJohn P.Lowe.
9. Quantum Chemistry –Ira N. Levine, Prentice Hall of India Pvt. Ltd.
10. Quantum ChemistryDonald A. McQuarrie, Viva Book Pvt. Ltd.
11. Physical ChemistryP.W. Atkins, Clarendon Press, Oxford, 1970.
12. Molecular Quantum MechanicsP.W.Atkins, Clarendon Press, Oxford, 1970.
13. Introduction to Quantum ChemistryJ. M. Anderson.
36 | P a g e
14. Introduction to Quantum MechanicsR. H. Dicke, J. P. Wittke.
15. Indroductory Quantum ChemistryA. K. Chandra, Tata McGraw Hill, New Delhi 1994.
16. Quantum Mechanics in Chemistry-M.W. Hanna.
17. Quantum ChemistryR .K. Prasad, New Age International Publishers, New Delhi.
18. Atomic Spectra and Atomic structureG. Herzberg, Van Nostrand
19. Chemical Applications of Group TheoryF.A.Cotton, Wiley Eastern, New Delhi
20. Molecular SymmetryD.S.Schonlnd, Van Nostrand Comp.London,1965
21. Symmetry in Chemistry-Jeffe and Orchin, Wiley Inter Science, NewYork.
22. Symmetry, Orbitals and SpectraJeffe and Orchin, -Jeffe and Orchin, Wiley Inter Science,
New York, 1971.
23. Electron DiffractionT.B. Rymer, Methuen, London,1970
24. Neutron DiffractionG.E.Becon
25. Symmetry in MoleculesJ.M.Hollar
26. X-Ray CrystallographyBuerger
27. Diffraction MethodsWernard
28. Chemical CrystallographyL.W.Bunn. N.Y.and Oxford,1945
29. Crystals and XRays K.landsdale, N.Y.1945
30. Crystal Structure AnalysisM.J.Berger, John Wiley and Sons, N.Y.1960
31. The Determination of Molecular StructureP.J.Wheatley, Clarendon, Oxford,1960
32. Physical ChemistryG.M.Barrow, McGraw Hill, New York, 1991
33. X-ray DiffractionD.B.Cullity, Mass Addison, Wesley, 1978.
CHG(Pr)3.4: Lab Course In Physical Chemistry
1. Viscosity: Determination of number average molecular weight by hydroxyl end group

analysis.
2. Conductance: Verification of the Debye–Huckel-Onsagr equation for strong electrolytes.
3. Reaction Kinetics: Studying the acid catalysed kinetics of oxidation of glycene by
chloramine–T (CAT) and hence determination of order of reaction w.r.t. CAT and glycene
and hence overall order of the reaction.
4. Potentiometry: Potentiometric estimation of a mixture of a halides, (KCl, KBr and KI) by
titrating against AgNO3
5. Cryoscopy: Determination of the molecular weight of the given solute by the vacuum flask
method.
6. pH metry: Determine the acid and base dissociation constant of an amino acid and hence
find its isoelectric point
7. Refractometry: Analysis of a binary mixture (glycerol and water) by refractive indices
measurement.
8. Spectrophotometry: Individual and simultaneous estimation of Fe(III) and Cu(II)
spectrophotometrically by titrating against EDTA.
37 | P a g e
9. X-Ray diffraction: To determine the lattice constant and Bravais lattice using X-ray
diffraction pattern.
10. Zeeman effect: Study the Zeeman effect and determine e/m ratio of electron.
Books Recommended:
1. Findlay`s Practical Physical Chemistry, 9th edition, revised by B.P.Levitt.
2. Practical Physical Chemistry by A.M.James and F.E.Prichard
3. Experiments in Physical Chemistry by Shoemaker and Garland 4. Experiments in Physical
Chemistry by Daniels, Alberty and Williams et.al.
4. Laboratory Physical Chemistry by Oelke/ M.A.C.T.L.A.C.
5. Experimental Physical Chemistry by W.G. Palamer
6. Advanced Physico-chemical experiments by J.Rose
7. Experimental Physical Chemistry by V.D.Athwale and Paul Mathur, New Age International
Publishers.
8. Text book of Physical Chemistry by S.Glasstone
9. Text book of quantitative analysis by A. I. Vogel
10. Advanced Practical Physical Chemistry by J. B. Yadhav, Goel Publishing house, Meerut.
iii.Viva-Voce & Journal : 05 marks
Total : 50 marks
IV SEMESTER
CHGT4.1: INORGANIC CHEMISTRY
UNITI
Organometallic Chemistry:
Chemistry of organometallic compounds with πbonding ligands: Synthesis, structure,
spectroscopy, reactions and bonding in metal–carbon πbonded systems involving dihapto to
hexahapto ligands Viz, olefins, acetylenes, allylic moieties, butadienes, cyclobutadienes, cyclo
pentadienes and arenes.
(12 Hours)
UNITII
Organometallic Compound as Catalysts:
38 | P a g e
Fluxinol behaviour of organometallic compounds, homogeneous and heterogeneous catalysis
involving metal complexes and organometallic complexes, oxidative additions, reductive
elimination, insertion and deinsertion reactions, hydrogenation, hydroformylation, isomerisation,
carboxylation, and polymerisation, water, gas shift reaction. Organometallic reagents in organic
synthesis: organo iron, organo copper and organopalladium compounds.
(12 Hours)
UNITIII
Instrumental Methods:
Thermogravimetric analysis (TGA): Factors affecting the resultsInstrumentation and

applications.
Differential thermal analysis (DTA): TheoryInstrumentation and applications.
Differential scanning calorimetry (DSC): Theory instrumentation and applications
Voltammetry: Fundamentals of voltammetry. Cyclic voltammetry: Principle and applications.
Stripping voltammetrybasic principle and applications,
Atomic absorption spectrometry: Theory, instrumentation, different types of nebulizers,
electrothermal vapouriser, cold vapour AAS determination of mercury, interferences, analytical
applications of AAS.
Molecular luminescence spectroscopy: Theory, instrumentation, factors affecting fluorescence
and its applications
(12 Hours)
UNITIV
Solid state chemistry
Electrical properties: survey of electrical properties and materials.

Super conductivity: Nature and properties of super conductivity material, Meinser effect, Type I
and II super conductors, Theories, high temperature oxide super conductors, junction involving
metal-super conductor. Applications.
Ionic conductivity: Alkali halides: Vacancy conduction. Silver chloride: interstitial conduction.
Solid electrolytes: βAlumina, AgI and Ag+ ion solid electrolytes. Anion conductors,
requirements for conductivity and Applications.
Magnetic properties: Mechanism of ferro and antiferro magnetic ordering ,seklescted examples
of magnetic materials, their structure and properties; metal and alloys, transition metal oxides ,
spines garnets ,ilemenites, perovskites, magneto plumbites, applications, structure-property
relation.
39 | P a g e
Optical properties: Luminescence and phosphorus, configurational coordinate model, some
phosphor material, antistokes, phophores, lasers.
(12 Hours)
Total: 48 Hours
IV SEMESTER
CHG(Pr): 4.5: LAB COURSE IN INORGANIC CHEMISTRY
1. Use of cation resin

2. Use of anion resin
3. Determination of iron(II) using 1,10-phenanthroline by colorimetry
4. Determination of composition of iron(II)-1,10-phenanthroline complex by Job’s and
Mole ratio methods
5. Determination of titanium (IV) using H2O2 by colorimetry
6. Use of oxine and salicylaldoxime in the separation and estimation using volumetric/
gravimetric method
i) Al + Mg and (ii) Cu + Ni
Books recommended:
1. A text Book of Quantitative Inorganic Analysis – A.I Vogel
2. Vogel’s Text Book of Quantitative inorganic Analysis, Basset, Denney, Jeffery & Mendham
3. Colorimetric Determination of Traces of Metals – E.B Sandell.
4. Analytical Chemistry, G.D. Christian, 5th edition, 2001 John Wiley & Sons, Inc. India
Total : 50 marks
Recommended Books:
1. Vogel’s Text Book of Quantitative Inorganic Analysis-J. Bassett, R. C. Denney, G. H.
Jaffery and J. Mandham, Longmans, Green and Company Ltd.
40 | P a g e
2. Chemical analysis of foods and food products-Morris B. Jacobs (3rd Edn.), D. Van Nostrand
Company, inc.
3. Standard methods of chemical analysisF. J. Welcher (6th Edn., Vol. 3 Part-B), D. Van
Nostrand Company, Inc. Indian, United States and European Pharmacopea.
4. General Chemistry ExperimentsA. J. Elias, University Press.
CHGT–4.2: ORGANIC CHEMISTRY:
UNIT–I
Heterocyclic Chemistry and Newer Reagents:
Heterocyclic Chemistry: Chemistry of three, four, and seven membered heterocycles with one
Heteroatom.
Three membered: Oxiranes, aziridines and thiranes.
Four membered: Oxetanes, azetidines and thietanes.
Seven membered: Oxepines, azepines and thiepines.
Newer Reagents: Methods of preparations, mechanism of action and application of the

following reagents in Organic synthesis:
DCC, 1, 3 Dithiane, LDA, DDQ, tributyl tinhydride, Wilkinson Catalyst, trimethyl silyl iodide,
Gilman reagent.
(12 Hours)
UNIT–II
Organic Photochemistry and Pericyclic Reactions:
Organic Photochemistry: Principles of photochemistry, photochemical processes, energy

transfer and photosensitization. Photochemical reactions: Photoreduction, Norrish type–I and II
cleavages. Di-pi methane rearrangement, optical pumping. Photochemistry of
cyclohexadienones, photo Fries rearrangement.
Pericyclic Reactions: Classification and features, Molecular orbital symmetry. Frontier orbitals
of ethylene, 1,3–butadiene, 1,3,5–hexatriene and allyl systems.
Electrocyclic processes: Woodward Hoffmann rules for 4n– and (4n + 2)π systems.
41 | P a g e
Cycloaddition reactions: Diels–Alder reaction, [2+2] and [4+2] cycloaddition reactions, Supra
facial and Antra facial addition.
Significance of Reactions: Sigmatropic rearrangement, supra and antra facial hydrogen shifts.
Claisen, Cope, oxy Cope and aza Cope Rearrangements. Vitamin – D group isomerisations.
(12 Hours)
UNIT – III
Oxidations, Reductions and Newer Reactions:
Oxidations:
Oxidation of organic compounds using KMnO4, PCC, OsO4, CrO3, K2Cr2O7, SeO2,
Pb(OAc)4, HIO4, Oxygen, Oppaneur oxidation, Swern oxidation.
Hydroboraton – Isomerisation and oxidation.
Reductions:
Reduction of organic compounds using the following reagents: LiAlH 4, NaBH4, DIBAL-H,
Dissolving metal reduction, Birch Reduction, Wolf-Kishner Reduction.
Newer Reactions:
Mechanism and Synthetic applications of the following Named reactions: Suzuki coupling,
Mitsunobu reaction, Pauson-Khand reaction, Heck arylation. Sonogashira reaction.
(12 Hours)
UNIT–IV
Medicinal Chemistry
Modern theories of drug action, concept of receptors, computer aided drug design, qualitative
and quantitative SAR.
Sulfa Drugs: Sulfadiazines, sulfamethazines, sulfaguanidines, sulfa isoxozoles, sulfamerazine.
Analgesics: Classification of narcotic and non-narcotic analgesics.
Narcotic: Opium alkaloids, morphine, metopon, benzomorphan and phenazocine.
Non-narcotic: 4–Phenylpiperidines–Pethidine, diisopropylamines, methadone, pyrazolones,
antipyrine.
Anti-fertility drugs: Steroidal and non-steroidal compounds norethindrone, mestranil,
Norgestrol and non-steroidal antifertility drugs.
42 | P a g e
Structural features and uses of common antibiotic drugs: Norfloxacin, rifamycin and
amoxycillin.
(12 Hours)
Total: 48 Hourss
Books Recommended:
1. An Introduction of the Chemistry of Heterocyclic Compounds - R. M. Acheson, 4th

Edition, John Wiley and Sons.
2. Heterocyclic Chemistry –A.R. Katritzky and J. J. Logowskii.
3. Heterocyclic Chemistry –T. L. Gilchrist, 3rd Edition, Pearson Education Delhi (2005).
4. Modern Heterocyclic Chemistry –Joules and Smith.
5. Heterocyclic Chemistry –R.K.Bansal,3rd Edition, New Age International Publishers, (2002).
6. Medicinal Chemistry Volume I and II–A. Burger, Wiley-Interscience New York
(1988).
7. Progress in Medicinal Chemistry Volume 1–8. Edited–G.P. Ellis and G. B. West. North
Holland New York (1974).
7. Organic Chemistry volume I and II –I. L. Finar, 6th Edition, ELBS London (2004)
8. Principles of Organic Synthesis–R.O.C.Norman and J.M.Coxon, 3rd Edition, Nelson
Thrones, UK (2003).
9. Organic Reaction Mechanism –R. K. Bansal, 3rd Edition, Tata McGraw Hill (2006).
10. Molecular rearrangements–I and II–P.de. Mayo.
11. Mechanisms of Molecular Migrations. Volume I and II–B.S. Thyagarajan, 1st Edition, Wiley
Interscience, London (1979).
12. Molecular Transformations in Organic Chemistry–D.Ranganathan and
13. S. Ranganathan, 1st Edition, McMillan India, New Delhi (1975).
14. Biotransformations in Organic Chemistry–K. Faber, 4th Edition, Springer, Asian Books
Ltd, (2002).
CHG(Pr)–4.6: Lab Course In Organic Chemistry
1. Multi-step preparation of organic compounds involving various reactions like addition,

elimination, oxidation, hydrolysis etc. and purification methods like distillation and
crystallization.
2. Identification of structure of the organic molecules based on spectra.
Books Recommended:
1. Vogel’s Textbook of Practical Organic Chemistry Revised–B.S. Furniss, A. J. Hannaford,

P.W.G. Smith, A.R. Tatchell, 5th Edition, Addison Wesley Longman Limited, UK, 1997.
43 | P a g e
2. A Hand book of Organic Chemistry–H.T.Clarke.
3. A Laboratory Manual of Organic Chemistry–B. B. Dey and M.V. Govindachari.
4. Lab Experiments in Organic Chemistry –Arun Sethi, New Age International Ltd. New
Delhi. 2006.
Duration of examination : 04 hours

Experiments : 35 marks
Journal and Viva : 05 marks
Internal Assessment : 10 marks
Total : 50 marks
CHGT–4.3: PHYSICAL CHEMISTRY
UNIT–I
Chemical Bonding-I:
Electronic structure of diatomic molecules. The Born–Oppenheimer approximatuion. Molecular
orbital and valence bond theories of chemical bonding, comparison of the two, applications to
hydrogen molecule and hydrogen molecule ion. Improvements in the Hitler-London wave
functions. Bonding and antibonding molecular orbitals. Molecular orbital theory applied to
homonuclear and heteronuclear diatomic molecules. Molecular electron configuration and
calculation of bond order. Slater orbitals, Hartee-Fock self consistent field method for many
electron atoms. Congfiguartion interaction and Roothaam equations.
(12 Hours)
UNIT–II
Homogeneous Catalysis:
Homogeneous catalysis: Introduction, General catalytic mechanism: Equilibrium treatment and
steady-state treatment, activation energies for catalyzed reactions. Acid-Base catalysis: General
acid-base catalysis, mechanism of acid-base catalysis, catalytic activity and acid-base strength,
salt effects in acid-base catalysis and specific acid-base catalysis: Bronsted relation and linear
free energy changes. Acidity functions: Zucker-Hammett hypothesis and Bunnett hypothesis.
Enzyme Catalysis: influence of substrate concentration, pH, temperature and inhibitors,
transient-phase kinetics. Mechanism of enzyme catalysis: Michaelis-Menten mechanism,
Lineweaver-Burk plot.
. (12 Hours)
UNIT–III
Statistical Mechanics and Statistical Thermodynamics-I:
44 | P a g e
Microscopic and Macroscopic systems. Microstates and macrostates. Assemblies of independent
localised and non–localised systems. Phase space or γ–space and μ–space. Ensembles.
Classical Statistics: Maxwell–Boltzmann distribution for ideal gases and mixture of gases.
Determination of Lagrangian multipliers, alpha and beta. Equipartition of energies.
Heat Capacities of Solids: Einstein's theory of heat capacity of solids, Debye's theory.
Characteristic temperature and use of Debye equation for the determination of heat capacity at
low temperature.
Sackur–Tetrode equation: Entropies and heat capacities of ortho–, para-hydrogen systems,
comparision of third law entropies with statistical entropies.
(12 Hours)
UNIT-IV
Rotation of Polyatomic Molecules and Rotational Spectra: Classification of molecules;

momental ellipsoid, energy levels of linear, symmetric, spherical and asymmetric top molecules
and their symmetry properties. Selection rules. Thermal distribution of rotational energy levels.
Infrared rotational spectra and non rigid rotor treatment.
Vibration of Molecules: Molecule as harmonic oscillator: vibrational eigen functions and eigen
values. Hermite polynomials; calculation of transition of probabilities and selection rules. The
anharmonic oscillator, energy levels, selection rules and IR spectra. Anhormonicity and Morse
equations.
Rotation–Vibration Spectra of Polyatomic Molecules: Rotation - vibration spectra, shapes of

absorption bands in case of (i) linear, (ii) symmetric top, (iii) spherical top and (iv) asymmetric
top, molecules. Isotopic effects. Applications of IR spectroscopy. Numerical problems on IR
spectroscopy.
(12 Hours)
Total 48 Hours
Books Recommended:
1. Quantum Mechaincs -L.T.Schiff, Prentice-Hall.

2. Quantum Chemistry- H. Eyring, J. Walter and G. E. Kimball, John Wiley.
3. Quantum Mechanics-An Introduction- H. L. Strauss, Prentice Hall of India.
4. Quantum Mechanics-L. Pauling and E.B.Wilson, McGraw Hill.
5. Contemporary Quantum Chemistry-J. Goodisman, Plenum/Rosetta.
6. Quantum Chemistry- K. S. Pitzer, Prentice-Hall
7. Introductory Quantum Mechanics-Valdimir Rojanstry.
8. Quantum Chemistry- John P.Lowe.
9. Quantum Chemistry –Ira N. Levine, Prentice Hall of India Pvt. Ltd.
45 | P a g e
10. Quantum Chemistry-Donald A. McQuarrie, Viva Book Pvt. Ltd.
11. Physical Chemistry- P.W. Atkins, Clarendon Press, Oxford, 1970.
12. Molecular Quantum Mechanics-P.W.Atkins, Clarendon Press, Oxford, 1970.
13. Introduction to Quantum Chemistry-J. M. Anderson.
14. Introduction to Quantum Mechanics-R. H. Dicke, J. P. Wittke.
15. Indroductory Quantum Chemistry- A. K. Chandra, Tata McGraw Hill, New Delhi 1994.
16. Quantum Mechanics in Chemistry-M.W. Hanna.
17. Quantum Chemistry- R .K. Prasad, New Age International Publishers, New Delhi.
18. Physical Chemistry by G. M. Barrow, McGraw Hill, New York, 1996.
19. Fundamentals of Physical Chemistry by Maron and Lando.
20. Physical Chemistry by P. W. Atkins, ELBS, London, 1990 (Ed. 4).
21. Physical Chemistry by K. Vamulapalli, Prentice Hall of India Pvt. Ltd., New Delhi, 1997.
22. Physical Chemistry by Daniels and Alberty, Wiley, New York.
23. Physical Chemistry Through Problems by S. K. Dogra and S Dogra, Wiley Eastern, New
Delhi.
24. A Text Book of Physical Chemistry by Samuel Glasstone, McMillan, London.
25. Atomic Structure and Chemical Bonding by Manas Chanda, Tata McGraw Hill Publishing
Co., New Delhi.
28. Statistical Mechanics-N. Davidson, McGraw-Hill, 1962
29. Introduction to Statistical Thermodynamics-M. Dole, Prentice Hill. 1954
30. Statistical Thermodynamics-R. H. Fowler and E. A. Guggenheim, Cambridge University
Press, 1939.
31. An Introduction to Statistical Mechanics-T. L. Hall, Addison Wesley, 1960.
32. Introduction to Statistical Mechanics-G. S. Rushbrook, Oxford University Press, 1949.
33. Statistical Mechanics-J. E. Mayer and M. G. Mayer, John Willey, 1940.
34. Textbook of Physical Chemistry by A. Singh and R. Singh, Campus Books International,
New Delhi
35. Introduction to Molecular Spectroscopy-G.M.Barrow, McGraw Hill
36. Physical Methods in Inorganic Chemistry-R. S. Drago East-West Press, New Delhi.
37. Molecular Spectroscopy-J D. Graybeal. McGraw Hill
38. Spectroscopy, Volume I,II,III Ed-B.P. Straughan and S. Walker Chapman Gall, 1976.
39. Molecular Magnetic Resonance Spectroscopy-R.M.L.Bell and R.K. Harris
40. Spectra of Diatomic Molecules, G. Hertzberg-D. Van Norstrand Co. Inc. Prenceton N.J.
1950
41. Infrared and Raman Spectra of Polyatomic molecules-G.Hertzberg, D. Van Norstrand
Co.Inc. Prenceton N.J. 1950
42. Absorption Spectroscopy-R.P.Bauman.
43. Molecular' Structure : A Physical Approach-J.C.D. Brand and J.C. Speakaman, Edward
Arnold Ltd., London.
44. Microwave Spectroscopy-J.M. Sugden and C.N. Kenny.
46 | P a g e
45. Fundamentals of Molecular Spectroscopy-C. N.Banwell, Tata- Mcgraw Hill, New Delhi,
1975.
46. Molecular Vibrations-E.B.Wilson, J.C. Decius and P.G.Cross.
CHG(Pr)–4.7: Lab Course In Physical Chemistry
1. Viscosity: Viscosity of air by Rankine`s method.

2. Solubility: Variation of solubility of Ca(OH)2 in NaOH solution and hence determination of
the solubility product of Ca(OH)2.
3. Thermochemistry: Heat of reaction (precipitation/formation) of BaSO4. c) Heat of transition
of Glauber's salt (Na2SO4.10H2O)
4. Surface Tension: Critical micelle concentration of a soap molecule. (e.g., Potassium
laureate).
5. Potentiometry: Determination of degree of hydrolysis and Kh of aniline hydrochloride
6. Polarimetry: Kinetics of inversion of sucrose and determination of catalytic coefficient.
7. Cryoscopy: Determination of activities of electrolytes and non-electrolytes using cryoscopy

method.
8. Spectrophometry: Investigation of complex formation between Fe+3 and Salicyclic acid:
formula, stability, ∆G value calculation and pH effects.
9. Glass transition temperature: Determination of glass transition temperature by dilatometer.
10. Solid state: To determine the electron-phonon coupling constant of copper
Books Recommended:
1) Findlay's Practical Physical chemistry, 9th edition, revised by B.P. Levitt.
2) Practical Physical Chemistry by A.M.James and F.E.Prichard
3) Experiments in Physical Chemistry by Shoemaker and garland
4) Experiments in Physical Chemistry by Daniels, Alberty and Williams et.al.
5) Laboratory Physical Chemistry by Oelke / M.A.C.T.L.A.C.
6) Experiments in Physical Chemistry by W.G.Palmer
7) Advanced Physico-Chemical experiments by J.Rose
8) Experimental Physical Chemistry by V.D.Athwale and Paul Mathur , New Age International
Publishers.
9) Text Book of Physical Chemistry by S.Glasstone
10) Text Books of quantitative analysis by A.I.Vogel
11) Advanced Practical Physical Chemistry by J.B.Yadhav, Goel Publishing House, Meerut.
12) Computers and their applications to Chemistry, Ramesh Kumari, Narosa.
13) A Lab Manual of Polymers, S. M. Ashraf, Sharif Ahmed, Ufana Riaz, I.K. International New Delhi.
47 | P a g e
Total : 50 marks
CHGP-4.4: Project Work
The project work may include implant training in Industries/short term work in the
Department/other educational institutions/R&D organizations/Data mining/Review of current
literature/ Theoretical methods/computer applications. Experimental work may involve studies
on synthesis/measurements/study of properties/characterization by physical methods/activities
for reported/unreported research or any suitable combination thereof
In case of the students who would work outside the campus, the supervising staff member may
visit to the work place at least once during the period and may be eligible for TA-DA as per the
University ruless
48 | P a g e

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KARNATAK UNIVERSITY

Choice Based Credit System

Theory Question Paper Format for CBCS Semester Examinations:

The other general academic regulations will be same as laid by University

No. of Duration of Internal

CHGT1.1: Inorganic ChemistryI 4 4 3 25 75 100

CHGT1.2: Organic ChemistryI 4 4 3 25 75 100

CHGT1.3: Physical Chemistry I 4 4 3 25 75 100

CHGT1.4: Analytical Chemistry 4 4 3 25 75 100

CHG(Pr)1.5: Lab Course in Inorganic 2 4 4 10 40 50

No. of Duration Internal

CHGT2.1: Inorganic ChemistryII 4 4 3 25 75 100

CHGT2.2: Organic ChemistryII 4 4 3 25 75 100

CHGT2.3: Physical ChemistryII 4 4 3 25 75 100

CHET-2.1: Applied Inorganic Chemistry

CHG(Pr) 2.4: Lab Course in 2 4 4 10 40 50

No. of Hrs/ Duration Internal

CHGT3.2: Organic Chemistry 4 4 3 25 75 100

CHGT3.3: Physical Chemistry 4 4 3 25 75 100

CHEOT-3.1: Applied Organic Chemistry

CHG(Pr)3.4: Lab Course in Inorganic 2 4 4 10 40 50

CHGT4.1: Inorganic Chemistry 4 4 3 25 75 100

CHGT4.2: Organic Chemistry 4 4 3 25 75 100

CHGT4.3: Physical Chemistry 4 4 3 25 75 100

CHGP4.4: Project Work* 6 4 8 25 125** 150

CHG(Pr)4.5: Lab Course in Inorganic 2 4 4 10 40 50

CHG(Pr)4.6: Lab Course in Organic 2 4 4 10 40 50

CHG(Pr)4.7: Lab Course in Physical 2 4 4 10 40 50

Total 24 28 21 130 395 600

CHOICE BASED CREDIT SYSTEM

CHGT1.1: INORGANIC CHEMISTRYI

Structures and Energetics of Ionic Crystals and Covalent Bonds:

Walsh diagrams and Bent’s rule.

Magnetism: Types, spin moment, spinorbit coupling.

Non-aqueous solvents: Classification of solvents, properties of non-aqueous solvents. Reactions

Solid State Chemistry:

1. Inorganic ChemistryPrinciples of Structure and Reactivity, 4thEdnJ. E. Huheey, E.A.

CHG(Pr)1.5: Lab Course in Inorganic Chemistry

3. Quantitative analysis of copper-nickel in alloy/mixture:

4. Determination of lead and tin in a mixture: Analysis of solder using EDTA.

5. Determination of Cr(III) and Fe(III) in a mixture: Kinetic masking.

6. Quantitative determination of iron(III) gravimetrically and calcium(II) volumetrically in a

7. Determination of iron(II) and nickel (II) in a mixture:

8. Quantitative analysis of chloride and iodide in a mixture:

1. Duration of Examination : 4 hours

3. Vogel’s Textbook of Quantitative Chemical Analysis, J. Mendham, R.C. Denney, J.D

CHGT1.2: ORGANIC CHEMISTRYI

Organic Reaction Mechanisms:

Classification of organic reactions: Meaning and importance of reaction mechanism.

Non-kinetic methods of Detrmination of Reaction Mechanism: Product identification, cross over

Nucleophilic substitutions (Aliphatic): Mechanisms of SN2, SN1 (rearrangements in SN1

Enantiomers, diastereomers, epimers, racemization, resolution. Stereochemical correlation.

Conformational analysis: Conformational study of n-Butane, ethylene, glycol, chlorohydrin.

Ring current as criteria for aromaticity. Annulenes and heteroannulenes [10-18].

CHG(Pr)1.6 : Lab Course In Organic Chemistry

1. Benzoic acid and benzyl alcohol from benzaldehyde (Cannizarro reaction).

i. Duration of examination : 04 hours

A critical account of collision and transition state theories.

Review on basic concepts of polymers and their classifications. Homopolymers, copolymers,