Pharma
Pharma
? Indicate the route of administration, in which drug enters the systemic blood
circulation, bypassing the liver
+Rectal
- Oral
- Intramuscular
- Subcutaneously
- In the joint cavity
? Drugs that get into the blood are best associated with
+Albumins
- Lipoprotein
- Gamma - globulin
- Glycoproteins
- Chylomicrons
? Lipophilic drugs…
+ Good absorbed in the GIT
- Poorly absorbed from the GIT
- No subjected to metabolic transformations in the liver
- Poorly penetrate the blood-brain barrier
6. Exctreted by kidneys intact
? Indicate the type of drug action that is developing by use of astringents for the
treatment of burns.
- Reflex
- Toxic
- Mediator
+Local
- Resorptive
? Indicate the type of respond, which is developing after using of mustard plasters
by bronchitis:
+ Reflex
- Toxic
- Mediator
- Local
- Resorptive
? Medications designed for resorptive action and possessing irritant action, better
to use:
+After meal
- Fasting, ie, for 30- 60 minutes before meals
- During meal
- For 10-1 5 minutes before eating
- Irrespective of food intake
? What is cumulation
- Lowering effect by re-taking of the drug
- Occurrence of unusual, not typical drug effects
+ Accumulation of the active drug substance in the body
- Special case of the acute form of habituation that develops in a short period of
time (3-4 introduction)
- Accumulation, summation of the effects of medical substance
? Tolerance is:
+ Reduce the effect of the medicinal substance after repeated administration
- Occurrence of unusual, not typical for the substance effects
- Accumulation in the body of the active substance or accumulation, summation of
its effects
- Special case of the acute form of habituation that develops in a short period of
time (3-4 introduction)
- Increased sensitivity of the organism to drugs after repeated administration
? Sensitization it is:
- Accumulation in the body of the active substance or accumulation, summation of
its effects
+ Increased sensitivity of the organism to drugs after repeated administration
- Special case of the acute form of habituation that develops in a short period of
time
- Occurrence of unusual, not typical for the substance effects
- Lowering effect after repeated administration of medical substances
? Embryotoxic effect:
- Effect on blood pressure
- Actions are accompanied by vomiting
- Effect on the system cytochrome p-450
- The drug's effects on germ cells with the change of the genetic apparatus
+ Toxic effectie on the embryo
? The following drugs can be introduced i/v:
- Dicaine
- Anestesin
+Lidocaine
- Cocaine
- Tannin
?Which response does not meet the requirements of local anesthesia drugs?
- High selectivity action
- Short latency
- Vasoconstriction
- Low toxicity and minimal side effects
+Vasodilation
? Indicate the effect that is not typical for the combination of novocaine with
adrenomymetics:
- Vasoconstriction
- Increasing of anesthetic effect
- Prolong anesthetic effect
- Reduced toxicity
+Vasodilation
? Pilocarpine:
+Excites M-cholinergic receptors
- Blocks M-cholinergic receptors
- Stimulates N-cholinergic receptors
- Excites M-N-cholinergic receptors
- Inhibits cholinesterase
? Physostigmine:
- Enhances the synthesis of acetylcholine
- Stimulate the release of acetylcholine
+ Delay the hydrolysis of acetylcholine
- Stimulates cholinergic receptors
- Increase the activity of cholinesterase
? Mark substances, with the use of which simultaneously excites M-and N-cholinergic
receptors:
- Acyclidin
- Pilocarpine hydrochloride
+Carbacolin
- Methacine
- Ipratropy
? Is applied by myasthenia:
- Atropine
- Pilocarpine
+Proserine
- Ipratropium
- Methacine
? Adrenaline hydrochloride:
- Excited societal advantages of alpha-adrenergic receptors
- Excited mainly beta-adrenergic receptors
+Stimulates alpha-and beta-adrenergic receptors
- Enhances the release of neurotransmitter
- Hinders neurotransmitter reuptake by nerve endings
? Adrenaline hydrochloride:
- Reduces bronchial tone
+Slows contractions of the heart
- Increases automatism of the heart
- Causes hyperglycemia
- Causes mydriasis
? Mark alkaloid, providing a clear depressant effect on the CNS and PNS. For his
actions characterized by: hypotensive and sedative effects, possible depression. It
is used in the treatment of hypertensive states.
- Atropine sulfate
- Physostigmine salicylate
- Platifillina hydrotartrate
- Muscarine
+Reserpine
? Is contraindicated by asthma:
- Izadrin
- Salbutamol
- Scopolamine
+Propranolol
- Epinephrine
? For sedation anesthetic drugs can be appropriately combined with the following
substances:
+Trancvilisators
- Cholinomymetics
- CNS stimulants
- Adsorbing drugs
- Astringent
? Which of the hypnotic drugs, increases the activity of microsomal liver enzymes.
- Bromizoval
+Phenobarbital
- Nitrozepam
- Methaqualone
- Zopiklon
? Levodopa:
- Used for treatment of epilepsy
+Increases the content of dopamine in the CNS
- Blocks the conversion of DOPA to dopamine
- Increases tone of muscles
- Stimulates cortex
? Morphine causes:
- Reducing pain of inflammatory origin
- Hypertension
- Stimulates the respiratory center
- Myosis
+Mydriasis
? Indicae neuroleptic.
- Promedol
- Nialamide
+Haloperidol
- Diazolin
- Lithium carbonate
? Mark the side effects that may occur with prolonged use of neuroleptics, except.
+Drug dependence
- Extrapyramidal disorders
- Addiction
- Sleepiness
- Lethargy
? Indicate tranquilizer
- Aminazin
- Haloperidol
- Droperidol
- Phenobarbital
+Flurazepam
? Analeptics:
+Stimulate the vital centers
- Depress the vital centers
- Are agonists of funds for anesthesia
- Are synergists neuroleptics
- Replace noothropicals
? Bromides cause:
+Strengthening of processes of inhibition in the cerebral cortex
- Reduction processes of excitation in the cerebral cortex
- Reduction of inhibition in the cerebral cortex
- Inhibition of the medulla oblongata
- Anxiolytic effect
? Methylxanthines include:
+Caffeine
- Aminalone
- Piracetam
- Droperidol
- Haloperidol
? Respiratory stimulant:
- Ketamine
- Codein
- Acetylcystein
- Libecsin
+Carbon dioxide
? Belong to bronchodilators:
+Fenoterol
- Dexamethasone
- Ketotifen
- Morfina hydrochloride
- Codeine
? Is a feature of salbutamol:
- Has mucolytic action
- Cause tachycardia and cardiac arrhythmias
- Used for bronchitis
+Is fast acting bronchodilators
- Expectorative
? What is the reason the therapeutic effect of ethyl alcohol by pulmonary edema:
- With its narcotic effect
- From dehydrating effect.
+With anti foming action
- On lowering the pressure in the pulmonary circulation
- With antimicrobial effects
? Drug used by distress-syndrome of newborns:
- Glucocorticoids
- Contrical
- Bronchodilators
+Surfactants
- Analgesics
? A drug that stimulates appetite:
- Pepsin
- Fepranon
- Cholosas
+Tinkture wormwood (artemisia)
- Indometatsin
? A substance that stimulates secretion of gastric juice and applied for diagnostic
purposes:
- Prozerin
- Carboholin
+Histamin
- Tincture of wormwood
- Pepsin
? Which drug do not provide protection of the gastric mucosa and duodenal:
- Inismuta tripotassium ditsitrat
- Mizoprostol
+Atropin
- Aluminescent hydroxide
- Sukralfat
? Specify gastroprotektor
- Atropine
- Essentsiale
- Panitidin
- Neostigmine
+Mizoprostol
? What is not typical for the positive inotropic action of cardiac glycosides?
- Increase in stroke volume of the heart
- Increase in cardiac output
- An increase in blood flow velocity
+Decrease in strength and speed of contraction of the heart
- Increased strength of heart contractions and shortening of systole
? What is the effect of cardiac glycosides on the content of calcium ions in cells
of the myocardium?
- Reduces the outflow of Ca2+ from the sarcoplasmic reticulum
- Decrease the concentration of Ca2+ ions in the cytoplasm of cardiomyocytes
- Difficult entry into cardiomyocytes of extracellular calcium ions
+Increases the output of Ca2+ from the sarcoplasmic reticulum
- Did not significantly affect the outflowt of Ca2+ ions from the sarcoplasmic
reticulum
? What determines the solubility of glycosides and their fixation in the tissues:
- Sulfur ions
- Aglycon part
- The state of the organism
+From glycon part
- The nervous system
? Find a drug:
Antianginal medications from the group of nitrates, increases coronary blood flow,
improves myocardial collateral blood flow, reduces the need for myocardial oxygen,
lowers blood pressure, reduces venous resistance.assign sublingually effect
develops after 1-2 minutes, maximum effect lasts for 20-30 minutes. Is applied by
angina attacks.
- Validol
- Nifedipine
- Propronalola hydrochloride
+Nitroglycerine
- Verapamil hydrochloride
? Find a drug:
Antianginal medications, irritating of cold receptors in the oral cavity and
reflexively dilates coronary vessels.the action develops within 1-2 minutes after
sublingual administration, duration of 10-15 minutes. Assign for relieving angina
attack.
+Validol
- Verapamil hydrochloride
- Nitroglycerine
- Nitrosorbit
- Nifedipine
? Find a drug:
Antagonists of calcium ions, increases coronary blood vessels and increases blood
flow in them, reduces the mechanical work of the heart and lowers myocardial oxygen
demand.it has antianginal and antihypertensive effects. Apply for prevention in
hypertension.
- Propronalola hydrochloride
- Sodium nitroprusside
- Novokainamid
+Nifedipine
- Nitroglycerine
? Find a drug:
B-adrenoblocker, reduces the frequency and strength of heart contractions, reducing
the need for myocardial oxygen. Has antianginal, antihypertensive and anti-
action.apply for the prevention of angina attacks, heart arrhythmia and
hypertension.
- Verapamil hydrochloride
- Adrenaline hydrochloride
- Novocainamid
+Propranolol hydrochloride
- Nitroglycerine
? Find a drug:
Reduces the resistance of coronary vessels due to inhibition of adenosine reuptake
and inhibition of the enzyme adenosine deaminase, inhibits platelet
aggregation.apply for the prevention of angina attacks, as antiaggregant in acute
myocardial infarction.
- Erinit
- Nifedipine
- Propranolol hydrochloride
+Dipyridamole
- Nitroglicerine
? What means has the following mechanism of the hypotensive action: reducing the
number of BCC and the extracellular fluid due to significant loss of Na and water.
Reduces total peripheral vascular resistance, potentiates the effect of
antihypertensive drugs.
- Reserpine
- Metildofa
- Benzogeksalin
- Propranolol hydrochloride
+Hypothiazide
? Ascorbic acid:
- Regulates fat metabolism
+Participates in the formation of hyaluronic acid and collagen synthesis
- antiulcer effect
- Improves the permeability of capillaries
- Inhibits the activity of redox Processes
? By rickets is used:
+Ergocalciferol
- Tocopherol
- Riboflavin
- Thiamine bromide
- Antiacrodynia factor
? Glutamic acid
+Participating in nitrogen metabolism, detoxifies ammonia
- It has lipotropic effect
- Participate uet in the metabolism of the lens
- Stimulates cerebral cortex
- Affects on GABA receptors
? Methionine
- Participating in nitrogen metabolism, detoxifies ammonia
+It has lipotropic effect
- Participate uet in the metabolism of the lens
- Stimulates cerebral cortex
- Affects on GABA receptors
? Cysteine:
- Participating in nitrogen metabolism, detoxifies ammonia
- It has lipotropic effect
+Participate uet in the metabolism of the lens
- Stimulates cerebral cortex
- Affects on GABA receptors
? To improve the metabolic processes in the solid tissues of the tooth orally and
parenterally is prescribed.
- Vitamin A and E
- Antiseptics
- Diclofenac sodium
+Calcium and fluoride
- Vitamin B
? Give drugs the anterior pituitary hormones:
- Thyroidin
- Pituitrin
- Vasopressin
+Chorionic gonadotropin.
- Oxytocin
? Applied by galaktorei:
- Pituitrin
- Estrone
- Progesterone
+Bromcriptin
- Retabolil
? Is applied by nanism:
+Somatotropin
- Adiurecrine
- Bromcriptin
- Tirotropin
- Insulin
? Merkozolil:
- Inhibits the production of thyroid stimulating hormone
- Destroys catecholamine follicular thyroid
+Violates the synthesis of thyroid hormones in th thyroid
- Mobilizer of intracellular calcium
- Stimulates adenylate cyclase
? Calcitonin:
- Influences on the reabsorption of sodium ions in water and in the kidney tubules
+Regulates calcium metabolism
- Stimulates - cells of the pancreas
- Secreted by the kidneys
- Distroyed by cholinesterase
? Is prescribed by myxedema
- Thyreocalcitonin
- Parathyroidin
+Thyroidin
- Merkazolil
- Metformin
? Is appointed by thyrotoxicosis
- Thyroxin
- Calcitonin
- Metformin
+Merkazolil
- Parathyroidin
? Insulin:
+Enables the transport of glucose across the cell membrane and targeted at
implementing the muscles, fat tissue
- Stimulates - cells of the pancreas
- Increases lipolysis
- Inactivated by insulinase
- Promotes calcification of bones
? Is antagonists of heparin;
- Vicasol
+Protamine sulfate
- Dipyridamole
- Warfarin
- Sinkumar
? Is antagonist of neodikumarine;
+Vicasol
- Warfarin
- Protamine sulfate
- Dipyridamole
- Sinkumar
? Macrolide antibiotic
- Chloramphenicol
- Tetracycline
- Azithromycin
- Clarithromycin
+Erythromycin
? Tetracyclines
- Has bactericide effect
- Affect the auditory nerves
+Form chelate compounds with ions of calcium and magnesium
- Have a narrow spectrum of activity
- Have low toxicity
? The group of tetracycline include:
- Amoxacilline
- Streptomitsin
- Gentamitsin
+Doxacycline
- Eritromitsin
? Aminoglycosides include:
- Tetracycline
- Oxacillin
- Azithromycin
- Ampicillin
+Kanamycin
? Streptomycin
- Violate the permeability of plasma membranes
- Has no ototoxic effects
- Effect on spirochetes, fungi, protozoa
+Used for tuberculosis
- Has a narrow spectrum of activity
? Polymyxin M sulfate
- Not a cyclic polypeptide
- Causes crystalluria
- Violates the protein synthesis
- Resistance develops rapidly
+Acts on gram-negative bacteria
? Gentamicin:
- Used exclusively locally
- Can get into the bone tissue and accumulate in it
+With prolonged use of which may have hearing loss and vestibular disturbences
- Which can be observed inhibition of hematopoiesis
? Sulfalen - is:
- Drug, which is used to treat eye infections
- The preparation of the group nitrofuranov, which is used to treat intestinal
infections
+Sulfanilamide for resorptive action, which is retained in the body up to 1 week
- Sulfanilamide, which is released by the kidneys in active form and is used to
treat urinary infections
? Specify fluoroquinolone:
- Nitroxolin
- Furodonin
- Oksatsillin
+Ciprofloxacin
- Nalidixic acid
? Select a product from the nitrofuran group mainly used to treat urinary tract
infections
- Furazolidon
+Furadonin
- Furatsilin
- Furaplast
- Furazolin
? Emetine hydrochloride
+Is an alkaloid of emetic root
- An alkaloid of thermopsis
- Have vomit and expectorant action
- Effective in syphilis
- Assined in tablets
? Idoksuridin
- Is used for the prevention of influenza
+Supresses replication of individual DNA-containing viruses used in herpetic eye
infections (ceratitis)
- Distroy penetration of virus into the cell, is used to treat hepatitis
- Indicated orally
- Antivirus drug
? Is applied by epidermomycosis.
+Grizeofulvin
- Ketokonazol
- Amfoteritsin
- Clotrimazol
- Tetratsiklin
6. Eritromitsin
? Is used by dermatomycosis
- Amfoteritsin
- Oxolin
- Gentamicin
+Clotrimazol
- Vidaribin
? Is assigned by candidiasis
- Oxalin
- Metronidazol
+Clotrimazol
- Tetratsiklin
- Ampitsillin
? Levamisole (dekaris)
- Is used for the treatment of extraintestinal trematodoses
+Distroys ascarida metabolism by blocking fumarate reductase
- Act like drugs antimony
- No causes paralysis of muscles of roundworms
- Need binding combination with laxatives
? Belong to antiseptics
- Imidazole derivatives
- Benzodiazepine derivatives
+Galogen containing substance
- Indole derivatives
- Ganglionblockers
? Mark the drug, the mechanism of action which associated with the release of
oxygen
- Cerigel
- Iodine alcohol
+Hydrogen peroxide
- Phenol
- Metilen blue
? Ethyl alkohol
- Has an antihypoxia action
- Is an oxidant
- Belong to neuroleptics
+Is an antiseptic
- Excites CNS
? Potassium permanganate
- Is a dye
- Has an enveloping effect
- Induces anti-inflammatory effect
- Chip off in the tissues of the molecular oxygen
+ Chip off atomic oxygen in the tissues
? Furacillin is applied by
- To disinfect laundry
- For water disinfection
- By increased sweating
+For treatment of wounds
- For disinfection
? Determine the drug that is not from the group of halogen compounds
- Pantotsid
- Lugol solution
- Chloramin
+Rezortsin
- Solution Iodine
? Ampicillin tablets
- Rp: Ampicillini 0,00025
Da tales doses № 20 in tabulettis
Signa. Take 1 table. 4 times a day orally
+Rp: Tabulettam ampicillini 0,25
Da tales doses № 20
Signa.at 2 pi. 4 times a day by mouth
? Chloramphenicol in suppositorium
- Rp: Laevomycetini 0,5
Sacshari 3,0
Misce fiat suppositorium
Da tales doses № 20
Signa.1 suppository 3 times a day enter the vagina
? Streptomycin in ampoules
? Chloridin powder
? Timalin in ampoules.
- Rp: Thymalini 1% - 10 ml
Da tales doses № 10 in ampullis
Signa. i/v 1 time per day 5 ml
? Diphenhydramine tablets
- Rp: Naphtizini 1% - 10 ml
Da tales doses № 5
Signa. 2 drops 2 times per day to bury in the nasal cavity
- Rp: Naphtizini 1% - 10 ml
Ds 1 drop 1 time per day to bury in the nasal cavity
? Oxytocin ampoules
? Cytitone ampoules
? Lidocaine ampoules
? Drops of aminazin
- Rp: Aminazini 0,2
Da tales doses n10 in dragee
Signa: 1 tablet 2 times a day
+Rp: Cordyamini 30 ml
Da.signa: 20 drops 2-3 times a day.
? Nifedipine dragee
? Triamteren capsules