GURPS Classic Bio-Tech
GURPS Classic Bio-Tech
Playtesters: Ed Bradley, Ray Cochener, James R. Dunson, Scott Farrow, John L. Freiler, Mark Halsall,
Paul D. Henrichsen, Bob Huss, Scott A. Hutchens, Daniel Jasman, Jr., Hunter Johnson, Don Juneau, Jonathan Lang,
M. A. Lloyd, Elizabeth McCoy, Phil Masters, Aaron Medwin, Chris Murray, John Nowak, Nana Yaw Ofori,
Ian Osmond, Chris Owen, Timothy Pulver, Gary W. Roe, Curtis Shenton and Bolie Williams IV
GURPS and the all-seeing pyramid are registered trademarks of Steve Jackson Games Incorporated. Pyramid and Illuminati Online and the names of all
products published by Steve Jackson Games Incorporated are registered trademarks or trademarks of Steve Jackson Games Incorporated, or used under license.
GURPS Bio-Tech is copyright © 1997 by Steve Jackson Games Incorporated. All rights reserved. Printed in the U.S.A.
ISBN 1-55634-336-1 2 3 4 5 6 7 8 9 10
INTRODUCTION
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Our online magazine includes new rules
Genetic engineering and other biotechnology are about to change the world and articles for GURPS. It also covers all
in ways we can only begin to guess at. the hobby’s top games – AD&D, Traveller,
Can we resist the temptation to tinker with our genes when the potential World of Darkness, Call of Cthulhu,
Shadowrun and many more – and other SJ
rewards include immortality? Will exotic wonder drugs soon be produced in Games releases like In Nomine, INWO,
cows and goats? Will genetically-enhanced plagues threaten to wipe us out, or Car Wars, Toon, Ogre Miniatures and
will bio-nanotech let us conquer disease and transform ourselves into post- more. And Pyramid subscribers also have
human superbeings? Just how do genetic engineering, cloning and braintaping access to playtest files online, to see (and
work, anyhow? comment on) new books before they’re
released.
GURPS Bio-Tech answers these and other questions by looking at current New supplements and adventures.
and future technologies from a science-fiction perspective. In this book, we’ll GURPS continues to grow, and we’ll be
take a detailed look at many of the biotechnologies that other GURPS books happy to let you know what’s new. A cur-
have taken for granted and see how they stack up against the latest developments rent catalog is available for an SASE. Or
in the real world. The answers may surprise you . . . check out our Web site (below).
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Using This Book errata and updates, and hundreds of pages
of information. We also have conferences
Biotechnology breeds its own jargon. While most unfamiliar technical terms on Compuserve and America Online.
are explained as they are introduced, definitions can also be found in the Glossary, GURPS has its own Usenet group, too:
p. 139. If you run into an obscure term, check the glossary. rec.games.frp.gurps.
This book introduces few new advantages or disadvantages, but does add a GURPSnet. Much of the online discussion
of GURPS happens on this e-mail list. To
wide range of new enhancements and limitations. These are explained in the join, send mail to [email protected] with
Appendix, p. 135. “subscribe GURPSnet-L” in the body, or
Finally, fictional quotes introduce many sections of this book. Capsule biogra- point your World Wide Web browser to:
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INTRODUCTION 3
1 BIOTECHNOLOGY
Tika Dawnstar frowned – she needed money. Her scholarship covered her
tuition in the University of Mars’ genetic engineering program, but cost of living at
Nix Olympica was awful, thanks to the terraforming taxes. She needed a winter job,
Biotech Tech Levels
TL1-3 (pre-1450). Farming leads to a
one that would pay for the cutting-edge neurovirus with which she hoped to practical understanding of basic heredi-
upgrade her brain in time to ace the upcoming term’s exam. ty; plants and animals bred for desired
Plugging into her biocomputer, she scanned the “Help Wanted” column on traits. Microbes exploited to make
GeneWeb. Assistant on a project to develop a pollution-eating, cryogenic bacteria bread, wine and cheese.
to clean up a vatspill on Titan? Bleah. Design new porkapple plants? Yuck. She was TL4 (1450-1700). Development of
the optical microscope makes cells visi-
a vegetarian, anyway. She scrolled down the page, then stopped. High Arcadia was ble for the first time.
an orbital habitat – an adventure theme park based on Greek mythology. They TL5 (1701-1900). Mendel develops
wanted a freelancer with grad-level expertise to design one of the creatures that laws of heredity. Nature of cells and
would populate the park: a lamia, with a snake’s body and a human head. Tika’s reproduction understood. Germ theory
eyes widened . . . The lamia was to be fully sapient! of disease developed, along with early
Wasn’t that illegal? Tika called up a law database and cross-checked: Nope. It vaccines. Darwin postulates evolution.
Galton theorizes eugenics.
was bioethically questionable, but High Arcadia was an autonomous extra-national TL6 (1901-1950). Mutation of plants
entity, not a signatory to the Genetic Regulatory Protocols; she could work with and microorganisms using chemicals
human DNA. Tika hugged herself – this would be fun! and radiation. Biochemistry comes into
She considered the problem. A snake/human cell fusion, so she’d have to its own. Penicillin and other antibiotics
smooth out the biochemical differences between species . . . and probably get lots of developed. Electron microscope allows
false starts and aborted embryos before she got it right, even if she rented time on viruses to be seen. Experiments in
eugenics.
the university’s vatbrain megacomputer. But she could do it with the facilities they TL7 (1951-2000). DNA, chromo-
were promising, and the advance would pay for her new brain! Humming to herself, somes and genes discovered, related to
Tika began composing her application letter to the Arcadia Entertainment Group. heredity. Genome mapping begins.
Recombinant DNA and transgenics
allow simple gengineering. Organ trans-
Biological manipulation is nothing new. Humans have been influencing the plants, genetic testing, and experimental
gene therapy and cloning.
genetics of plants and animals for thousands of years through selective breeding. TL8. Human genome is mapped and
For example, most sheep once had long legs. That’s better for the sheep, since they sequenced, along with the genomes of
can run away from predators, but not so good for a farmer, who finds it harder to many other terrestrial animals. Complex
control and shear a nimble animal. So shepherds bred the sheep with shorter legs genetic modifications become possible.
together. The result? After many generations, the “improved” sheep are all short- Cloning perfected. Artificial wombs
legged, and farmers need specially-bred sheep dogs to keep the predators away. (“growth tanks”).
TL9. Mature gengineering. Limited
The trouble with selective breeding is that it takes generations to produce results. genetic control over mental traits.
Consequently, much of what we know about genetics comes from studying organisms Development of bio-nanotechnology
that have relatively short lifespans, such as fast-growing plants, fruit flies or bacteria. permits braintaping and the use of
Today, dramatic breakthroughs in molecular biology have led to genetic engi- nanoviruses in germline gengineering.
neering, a technology that allows the work of centuries to be done in months or TL10. Gengineering of complex
mental traits, such as intelligence.
years. In the 21st century, gengineering may create modified animal species, or
Routine genetic reconstruction of
even an “improved” breed of human. But who determines what is an “improve- ancient DNA traces.
ment” – the sheep or the shepherd? TL11. Living machines. Sensa-skin.
Nanoviruses and gengineering can alter
the fine structure of an adult mind.
TL12. Complex nanoviruses, includ-
ing contagious ones, make radical trans-
formations possible in humans and ani-
mals.
TL13+. Near-total control over bio-
logical processes through mature nan-
Basic Principles
All terrestrial life is made up of cells: one cell in the case of simple organisms
otechnology. Chrysalis machine.
The time frame after TL7 is simply
speculation. Also, while the GURPS
Basic Set suggests that TL8 may repre-
like bacteria or protozoa, and about 800 billion in a human. A cell consists of a mem- sent 2001-2050, it’s possible that
brane which encapsulates a watery soup of subcellular bodies. Among the most biotechnology will outpace this – in
important of these are skinny strands called chromosomes. Bacteria (the simplest life fact, if the wildest prophets of molecu-
forms) have a single chromosome (and several, smaller ring-shaped bodies called lar nanotechnology prove to be on tar-
get, we might even see a TL increase in
plasmids). In more complex forms of life, multiple chromosomes are housed inside a the field of biotechnology each genera-
nucleus in the center of the cell; e.g., each human cell contains 23 pairs of chromo- tion, or even each decade! Thus, instead
somes. Every cell in a particular organism, except the reproductive cells, has the same of being “far, far future,” TL13 biotech
number and type of chromosomes. Collectively, the chromosomes form an instruction may be 2100 or even 2050!
manual that contains all the information an organism needs to grow and reproduce. Continued on next page . . .
BIOTECHNOLOGY 5
Chromosomes are made of
deoxyribonucleic acid, or DNA. This
Biotech Tech Levels is a long, complex molecule with a
(Continued) tightly-coiled “double helix” shape,
resembling a twisted ladder. The
“rails” are formed from deoxyribose
This assumption has been incorpo- sugar and phosphate molecules,
rated into some of the vignettes in later while each “rung” on the ladder is
chapters, which explains why several of
composed of two compounds, called
the personalities “live through” multiple
tech levels.
bases, locked together to form a pair
– either the molecules adenine and
guanine (an AG pair), or cytosine
Tech Level Variations and thymine (a CT pair).
It’s perfectly possible to have a soci- If chromosomes are an instruction manual, then these base pairs (approximately
ety in which certain developments in 3 billion in a human!) can be thought of as the “letters” in the “genetic code” that it
technology, such as biotech, are more is written in. To continue the analogy, particular arrangements AG or CT base pairs
or less advanced than other types of form words, and a single coherent sentence is a gene. Each gene (there are as many
technology. In fact, this is strongly rec- as 100,000 in a human) contains a specific instruction that tells the cell how to man-
ommended for certain campaign set- ufacture the chemicals needed for life.
tings.
A gene sends out instructions to the cell by making a copy of the genetic code
For instance, the average cyberpunk
world background (as described in using messenger RNA (ribonucleic acid). Messenger RNA carries a gene’s instruc-
GURPS Cyberpunk) may be TL8 over- tions to big, lumpy molecules that float around the chromosome, known as ribo-
all, but medicine, biotech and cybernet- somes, which are the cell’s biological factories. They read the genetic message writ-
ics are usually at TL10 or TL11 – ten in the RNA as an instruction to start or stop manufacturing a particular protein
sometimes even higher. A “nanopunk” (see below) from available chemicals.
world may be TL8-9 in the physical Proteins are complex molecules (made of amino acids) used in cellular chemi-
sciences but TL12-13 in biotech and cal reactions. Some proteins make up the structure of cells. Others, called enzymes,
nanotech. act as catalysts to induce molecules to form new combinations, or break complex
Likewise, some alien species or molecules (such as food) down into smaller components. What differentiates one
exotic human cultures may follow a dif- species or individual from another are the different proteins that their cells produce,
ferent path, leading to TL9+ in biotech
and the order in which they produce them. These metabolic processes – digesting
but a much lower tech level in other
areas. This is especially likely for aquat- chemicals from food and making more DNA, RNA and enzymes so that cells can
ic species, or those evolving in gas giant replicate – are what characterizes life on the cellular level.
atmospheres. Cells replicate by splitting in two. When this happens, each of the chromosomes
GMs should also feel free to adjust within them also divides down the middle, so that both new cells have a copy of
the tech level at which different each chromosome. These half-chromosomes then reconstitute themselves from the
biotech inventions appear. If you think loose chemicals in the cell. In this way, each cell remains an exact duplicate of the
braintaping should be TL12 rather than original. In the case of asexual, single-celled organisms like bacteria, this ensures
TL9, there’s no real reason why it that each one is identical.
can’t be . . . Multicellular creatures that reproduce sexually are an exception to this. Each
parent’s reproductive cells carry only half the normal number of chromosomes.
When they unite (in a human, when an egg is fertilized by sperm), they form a sin-
gle, complete cell with the full number of chromosomes. Half of the chromosomes
(and their genes) come from one parent, half from the other. After this, the joined
cell replicates normally.
As a multicellular organism grows, genes are activated to cause individual cells
to specialize. Some become nerve cells, others become skin cells and yet others
form different organs, et cetera – all in accordance with the instructions carried in
their genes. In humans, a fertilized egg (zygote) develops first into a blastocyst, then
an embryo, and finally a fetus that is eventually capable of surviving outside the
womb as a baby.
Gengineering Techniques
Genetic engineering, or “gengineering,” is the practice of manipulating genes to
produce desired changes in an organism. The foundations of gengineering were laid
in 1950s, when Watson, Crick, Franklin and Wilkins described the structure of
DNA. Watson and Crick identified it with the basic blueprint of life (1953), and
determined that all terrestrial life forms seemed to share a universal genetic code.
6 BIOTECHNOLOGY
In the 1970s, it was discovered that proteins called restriction enzymes (derived
from certain bacteria) could act like molecular knives, slicing DNA molecules at
predetermined points, while another enzyme, ligase, could function like a molecular
glue to rejoin these pieces. Since all life on Earth has the same genetic code, the
genes are, in a gross but wonderful sense, a box of interchangeable parts. Using
restriction enzymes and ligase, scientists found they could chop fragments out of
one organism’s DNA and splice them into another, resulting in “recombinant
DNA.” Thus the discipline of genetic engineering was born.
At first, only simple bacteria could be gengineered, but by the 1980s, scientists
had learned how to “cut and paste” genes into more complex plants and animals.
Since DNA is a universal code, genes from one species can be added to another,
producing transgenic life forms that possess traits from multiple species.
By the 1990s, many transgenic life forms, from simple bacteria to higher mam-
mals like mice and pigs, had been developed and even patented, for both research
and commercial purposes. Ethical considerations have so far prevented the creation
of transgenic humans, but human genes have been inserted into other organisms.
Genetic engineering has also been performed on humans to fix genetic defects (such
as immune deficiency or cystic fibrosis), using a process known as gene therapy.
So how does gengineering work?
Sophisticated chromosome-mapping techniques (see Human Genome Project,
p. 14) are used to determine which genes do what. The desired genes can then be
cut out of cells (using restriction enzymes) and placed into bacteria, where they are
copied as the bacteria reproduce. Since the 1980s, however, the favored method has
been a technique known as the polymerase chain reaction, or PCR; see p. 13. A
Prokaryotes
genetic engineer can create a computer model of the genetic sequences he wants, and Eukaryotes
then mix together the basic building blocks to assemble DNA molecules in the lab.
By copying the sequences of existing genes, genetic engineers can produce genes At the cellular level, a yeast is more
that they know will be functional. Alternatively, they can analyze proteins and use closely related to a human than either
that information to devise genes that will produce those proteins. are to a bacterium. Terrestrial life is
divided into two main categories:
Strands of DNA don’t do any good just sitting in a test tube, though. If the prokaryotic organisms (like bacteria)
DNA is to be added to a different species, it must be further modified so that it will and eukaryotic organisms (like fungi,
actually do something (“express itself”) when inserted into the host organism’s plants and animals). The cells of
cells. To do this, genetic engineers must construct a partially artificial gene that eukaryotic and prokaryotic life forms
obeys the regulatory mechanisms of the host species. Altered DNA also needs a have certain fundamental differences.
way to enter the cells of the organism it is to modify. Some of the methods used by For example, eukaryotic cells possess a
gengineers to accomplish this are: clearly-defined nucleus, as well as pos-
sessing introns (see Junk DNA and
Gengineering, p. 10) and organelles
(see Eve, Eukaryotes and Organelles, p.
8).
While the two major branches of life
on Earth are the prokaryotic bacteria
and the eukaryotes, a third division has
recently come to light. These are bacte-
ria-like microorganisms that have been
named archaea (meaning “ancient” in
Microinjection: A favored method is to inject genetic material into target cell Greek), because they have been around
nuclei, either with a tiny needle or by using a “gene gun” which uses compressed on Earth for billions of years. When
gas to fire very tiny pellets (often gold dust) coated with genetic material. first discovered 20 years ago, these
Microinjection is the preferred method when genes need only be delivered to a sin- “archaebacteria” were thought to be a
gle cell (such as a bacterium or egg cell) in a lab dish. very ancient type of bacteria with odd
Bacterial Plasmids: Plasmids are small rings of DNA found in bacteria outside properties; e.g., some archaea species
have a methane-secreting metabolism
their chromosomes. Some types of soil bacteria, such as Agrobacterium tumefa- and live in high-temperature thermal
ciens, have the habit of inserting pieces of their plasmids into plants, transferring vents. However, recent research sug-
some of their DNA to the plant’s chromosomes, resulting in tumors. Scientists have gests that they are quite different on a
been able to modify these plasmids into vehicles for the transport of recombinant genetic level – two-thirds of the genes
genes, and they are useful tools for gengineering many plant species. However, this of archaea do not resemble those of any
method is ineffective on animals and some plants. other living creature, suggesting a
Retroviruses: In their natural state, retroviruses (“RNA viruses”), such as HIV, divergence from bacteria at least three
billion years ago.
enter a living cell and take over its metabolism. They inject their RNA into the cell,
taking over its cellular machinery and forcing it to make copies of the virus. Genetic
BIOTECHNOLOGY 7
engineers have turned this ability to their advantage. They modify the retrovirus so
Eve, Eukaryotes that instead of hijacking the cell to make viruses, it deposits the new gene. One pit-
fall of this method is that viruses are hard to selectively target – this procedure often
and Organelles produces many failures for each success, and there is a very slight but real danger
that the virus will deposit genes in the wrong place, or damage existing genes,
One of the major differences resulting in unintended defects or even cancer. However, retroviruses have the
between bacteria (prokaryotes) and advantage that they can be used to deliver genes to many cells at once, which makes
more advanced organisms (eukaryotes) them useful for gene therapy (see p. 9). In the future, “smarter” tailored viruses with
is that the latter possess miniature,
organ-like parts called “organelles.”
greater discrimination may be developed.
Organelles are located outside the Artificial Chromosomes: The problem of knowing where to put recombinant
cell’s nucleus, and perform specialized genes may be solved in some cases by creating completely synthetic chromosomes.
tasks, much like our body’s organs. For This has been done in the lab (as of 1997) and may prove to be a useful tool. A new
example, the mitochondria are bundles chromosome will be very obvious to any genetic test, though!
of rod-like organelles where vital, ener- Nanoviruses: At present, retroviruses and microinjection are the most common
gy-releasing chemical reactions take ways of inserting genetic material. However, 21st-century gengineering may use
place. These energy factories consume
oxygen to break down sugars and acids,
more exotic techniques. One possibility is the nanovirus, a protein-based “organic
then capture the resulting energy for the robot” capable of performing sophisticated molecular and cellular engineering.
cell’s use. Other types of organelles Nanoviruses may be radically gengineered retroviruses or white blood cells, or com-
include plastids (organelles where pho- pletely artificial constructs. They pass harmlessly through cell membranes and take
tosynthesis takes place in plants) and over cellular machinery using their own artificial enzymes, then alter or insert genetic
undulipodia (whip-like bodies found in material or other chemicals. They communicate with each other using specialized
the tails of sperm). enzymes, and even cooperate, coordinating their operations. Nanoviruses are power-
Organelles resemble tiny bacteria –
in fact, they possess minute amounts of
ful tools, and are the basis of many ultra-tech gengineering projects, taking over
their own DNA and RNA. In effect, from clumsier tailored viruses in tasks such as germline gengineering.
they have their own tiny genomes. A
growing body of recent evidence sug- So what can you do with recombinant DNA? Some possibilities are . . .
gests that in the distant past, organelles
were originally free bacteria, but were
engulfed by other bacteria and incorpo-
rated into them as symbiotes. Our
Gene Cloning
Genetic engineering techniques can be used to isolate the particular gene that pro-
genetic code seems to show that it was
this evolutionary leap that transformed
duces a given protein. That gene can then be inserted into a fast-reproducing bacterium,
prokaryotes into the more complex creating a transgenic species. What good is that? We’ll demonstrate with an example:
eukaryotic species, enabling them to The protein insulin is vital for treating diabetes. It’s produced naturally in the
evolve into plants and animals. human pancreas, but harvesting it from humans is not practical. Before gene
Organelles – specifically, the mito- cloning, insulin was harvested from other animal species, but this required expen-
chondria – have helped scientists study sive purification and sometimes had side effects. What was needed was a way to
the way species have evolved. When an mass-produce pure human insulin in large quantities. This was accomplished by
organism reproduces sexually, the sperm
and egg unite to combine the mother’s
using recombinant DNA techniques to splice the gene that makes human insulin into
and father’s genetic information. a bacterium. If the genetic engineering is properly performed, the bacterium will
accept the foreign gene. The human gene will then “express itself” by telling the
Continued on next page . . .
bacterium to manufacture the desired protein.
Bacteria can reproduce every half hour or so if they are sup-
plied with the proper nutrients and their temperature is carefully
regulated. Each time they reproduce, they double their popula-
tion; in a day, there might be a few million of them. When a
large enough biomass of bacteria exists, the mass can be
processed to extract the protein. A little more finesse in the
genetic engineering may even produce a bacteria that excretes
the protein itself. If a large enough vat is used, tons of commer-
cially-useful proteins can be produced.
This process has been used successfully since the 1980s.
While late-TL7 gene cloning techniques of this sort focus on
compounds that are medically useful (such as insulin or growth
hormones), TL8+ techniques may widen this to include numerous
proteins with exotic industrial applications. As genetic engineer-
ing labs become more widespread, it’s possible to imagine gene
cloning being used to produce substances such as illegal drugs.
In addition to naturally-occurring, medically-useful proteins,
gengineering has spurred the design of new ones with novel
8 BIOTECHNOLOGY
characteristics, such as tailored enzymes designed to perform specific chemical reac-
tions more efficiently than conventional catalysts. In the 1990s, only a few dozen
enzymes were used for industrial purposes, such as detergents or food sweeteners,
but enzyme engineering will be a major industry in the 21st century. Many future
products, from superior plastics to new foods and wonder drugs, may use genetically
modified (“genemod”) enzymes in their manufacture, and such enzymes may even
be the first step toward building nanomachines.
BIOTECHNOLOGY 9
high-security areas. However, considerations of privacy may lead to laws that limit
the widespread use of genetic identification.
DNA Forensics: Analysis of trace DNA samples – such as remains, or bodily
fluids left on a crime scene or victim – can be matched with genetic records in a
database. This can identify who was involved. If no match comes up in the databas-
es, suspects can be tested. Trait analysis can also be performed, and may provide
clues as to the identity of the perpetrator or unidentified victims. At mid-to-late
TL8, genome information can even be used to create a rough computer simulation
of what the subject might look like (in the absence of cosmetic surgery) assuming
various ages and environmental influences, such as diet.
Genetic Targeting: At high TLs, DNA information may be used to create target-
seeking diseases (p. 89) or nanoviruses (p. 84) that can home in on specific individuals.
Testing Procedures
Genetic testing at TL7 must be performed in a laboratory. Forensics skill and a
day or more of work may be required to properly gather samples. Genetics skill and
at least three hours will be needed to compare the DNA of one suspect with another;
commercial labs usually take about six weeks to report. Trait analysis requires at
least a day’s work. Critical failure can result in the contamination and misidentifica-
tion of samples. If samples are very small (e.g., only a tiny trace of blood), apply a
-4 penalty. A rush job (3-4 hours) is made at a -2 penalty; there is no modifier for
taking a full day, while taking a full week gives +2.
At TL8, a portable genetic scanner can take samples in a few seconds (prick a
finger, for instance), analyze them and upload the data to a computer for an instant
cross-check against a database. A pocket scanner is $500 and one pound at TL8; roll
Junk DNA vs. Electronics Operation (Sensors)+2 or Forensics+2 to use it. An expert system pro-
gram capable of performing on-the-fly genetic trait analysis (at skill 10, takes about
and Gengineering ten minutes per attempt) is Complexity 3 and $50,000 at TL8. Each +1 to skill dou-
bles cost and increases Complexity by one. All weights and prices are halved one TL
later, and halved again two or more TLs later. People like police officers will usually
Genes that make proteins used by
the body only account for about 2% of be able to connect their personal computers to computers running multi-million dollar,
the genetic material on the chromo- high-Complexity programs in major facilities (e.g., FBI crime labs) for rapid analysis.
somes of most species. Much of the rest At TL9+, bioscanners (p. UT19) can perform genetic scans. As well, forensic
are regulators for control sequences microbots – or nanomachines, at higher TLs – can be introduced into a crime scene to
which tell the genes when to turn on or locate nearly all traces of blood, tissue and other evidence in a few hours. These can
off. In eukaryotic organisms (such as uncover traces dating back weeks or months. A package of forensic microbots or
humans) there are also introns – long,
nanobots is $2,000. See p. UTT83 for more information on forensic nanomachines.
seemingly meaningless “junk DNA”
sequences with no apparent function.
Eukaryotic cells possess mechanisms to
ignore the intron sequences when mak-
Genetic Testing and Privacy Issues
ing proteins. Whose genetic records end up in a genetic database, and who are they accessi-
How did these “worthless” introns ble to? This is a major legal question for the 21st century.
get into the genetic code? One theory is Currently, most genetic testing is done by hospitals, at the request of patients
that they represent changes introduced who want to see whether they have any hereditary defects, usually because there is a
by ancient viral hitchhikers, or are sim- history of such problems in the family and they are considering having children.
ply the genetic debris of evolutionary Some genetic testing is also performed under legal auspices, generally for
dead ends. It’s also possible that they
forensic purposes – especially in rape cases, and to determine parentage in custody
act as “genetic speed bumps” to slow
down and regulate the rate at which cer- or paternity suits. At present, genetic testing usually requires a search warrant, or
tain proteins are manufactured. Maybe may be administered on a voluntary basis to prove one’s own innocence.
they act as genetic “spare parts,” usable For the moment, only people who have undergone these tests end up in law-
in future mutations. In a cinematic cam- enforcement genetic databases. In the 1990s, the FBI had DNA profiles on over
paign, introns may have a more sinister 100,000 people, mostly prisoners. Meanwhile, the U.S. Army is genetically testing
purpose – they could contain latent its personnel and developing portable scanners. The announced purpose is to make
genetic sequences that await the proper
it easier to identify the remains of dead soldiers.
control signal to activate. Perhaps they
would express themselves as super- The question of whether employers can test workers or job candidates is controver-
powers! sial. For example, current genetic tests can determine susceptibility to some hereditary
Continued on next page . . . diseases. If testing showed that someone had a greater-than-usual risk of developing
medical problems (even late in life), then they might be perceived as a potential burden
on corporate health care plans. There is also the risk of lost productivity if they get sick.
10 BIOTECHNOLOGY
As a result, they might not be hired, and might even lose existing jobs or health
insurance. Similarly, insurance companies may wish to test applicants. As testing
gathers more data on genes that influence human behavior, discrimination could be
Junk DNA
extended toward people with hereditary tendencies toward “undesirable” mental and Gengineering
traits.
Other issues related to genetic testing include the screening of the unborn: If an (Continued)
embryo or fetus tests positive for a birth defect – or just isn’t up to par – should it be If genetically-engineered critters are
aborted? Or should genetic surgery be attempted? Then there’s the question of manufactured from scratch (TL9+), the
whether a person would want to know that he has a higher risk of coming down designer may decide not to include
with a disease – or that his genes say he has less potential for intelligence or mental introns, to make his task simpler and the
stability than is the norm. Finally, there are worries about the security of genetic results easier to predict. This means that
information. If a cautious couple get tested to ensure they won’t pass on hereditary gengineered organisms may have high-
conditions to their children, can they be sure that their genetic data won’t also find ly-compact genomes. This would be a
good way to tell if a blood sample is
its way to insurance companies or employers? from an evolved organism or a manu-
Just how widespread genetic testing becomes may vary from country to coun- factured one. Of course, without all that
try, and in a GURPS Space campaign, from planet to planet. In many countries “junk” to work with, there will be very
today, there is political support for laws to limit testing in order to protect genetic little chance of novel traits developing
privacy. In a “dark future” like GURPS Cyberworld, though, these may be repealed spontaneously.
to serve the interests of megacorporations and repressive governments. One “far out” use for introns would
be to code non-genetic information into
an organism’s cells. For example, trade-
marks, serial numbers, secret messages
or other data could be “written” into an
organism using coded arrangements of
introns! And what if ancient astronauts
coded an interstellar “treasure map” into
our introns?
BIOTECHNOLOGY 11
If a scientific lab is hired to perform a genetic reconstruction, the process will
Heredity usually take from two to six weeks (depending on the difficulty) and cost $5,000 per
week.
If a scientist wants to attempt a reconstruction, the GM first determines if there
In the nineteenth century, a monk
named Gregor Mendel studied pea
is enough genetic material to make it possible. Reconstruction requires a genetics
plants. He postulated that each inherited lab, a Genetic Replication computer program (Complexity 6, $40,000) and a suc-
trait (like whether a plant is short or cessful Genetics roll. Suggested modifiers: -10 for DNA traces, -5 for actual tissue,
tall) is determined by a specific factor, 0 for a complete corpse; -15 at TL7, -10 at TL8, -5 at TL9, or 0 at TL10+. Roll each
which we now call a gene. An organism week; success indicates the process succeeded and a clone can now be made. A fail-
has two copies of each trait’s gene. In ure requires further work (one week times the number the roll was failed by). A crit-
reproduction, each parent passes half of ical failure indicates a mistake; an attempt to grow a clone will produce a flawed
its genes (determined semi-randomly)
to its offspring. The other half come
copy, a dead, non-viable one, or (possibly) a monster – GM’s option.
from the other parent.
For example, flower color in plants
is a genetic trait. If one plant has red
flowers and the other has white, will the
Biomimetics
Biomimetics is the branch of materials engineering that deals with the develop-
flowers of their offspring be pink? No!
This is because those genes don’t blend ment of synthetic designs modeled on biological materials. Natural materials often
together. Instead, the offspring of a have extremely complex molecular structures. Rather than copying these directly,
cross between white and red parents biomimetics seeks to improve on nature by using them as templates for synthetic
would also be either red or white. molecular designs.
Which gene is obeyed depends on Designing synthetic versions of natural polymers – like snail shells, wood or
whether that gene’s trait is a “recessive” insect chitin – could lead to stronger and tougher materials. As well, since many
or “dominant” one. If red flowers were
dominant over white for a particular
biomaterials can sense and respond to their surroundings, a major goal of biomimet-
plant, then the hybrid offspring would ic technology is to develop “smart” materials capable of altering texture, color or
be red. shape, sensing and repairing stress and damage, or even growing. Primary applica-
However, that isn’t the end of the tions include armor, cybernetics, sensors, textiles and waterproof, weatherproof,
story. While the hybrid plant looks red “chameleon” or “stealth” coatings.
(this is called its phenotype) its actual Many of the TL8+ items in GURPS Ultra-Tech already employ biomimetic
genes covering color (or genotype) are a materials. The most obvious is bioplastic (see p. UT17), but more subtle applica-
mix of one for redness and one for
whiteness. Suppose it is cross-pollinated
tions also exist. For example, some archaebacteria (see Prokaryotes and Eukaryotes,
with another red hybrid that has one red p. 7) live at very high temperatures in ocean thermal vents. Their heat-stable mole-
and one white gene. The luck of the cules could be adapted for many industrial and pharmaceutical processes, ranging
draw may lead to their offspring having from detergent additives to ablative armor (p. UT73). A more widespread biomimet-
two red genes (thus being red), a red ic technology is “bioglue” – a range of a biodegradable, waterproof adhesives based
and a white gene (also red), or two on the naturally-secreted, protein-based glue used by limpet mollusks. Bioglue can
white genes (white!). Thus, two plants be found in many TL8+ surgical kits, replacing conventional surgical sutures, since
with red flowers can produce one with
white flowers.
it does not need to be removed; it is also the adhesive base for plastiskin patches (p.
UT94). Besides its medical uses, bioglue is used to assemble many TL8+ composite
Continued on next page . . . materials and in ultra-sticky tangler strands (p. UT51).
Biotronics
This technology uses organic, protein-based systems rather than inorganic mol-
ecules for information storage and processing. Some biotronic technologies on the
RR + WW horizon are . . .
Biosensors (TL7/8)
A biosensor is an electronic device that consists of a ordinary computer chip
RW + RW coated with a layer of biological molecules that selectively bond with a specific,
known compound. When this occurs, the chip sends a signal that these molecules
are in the area. Depending on the design, a biosensor can be used as a contact sensor
to identify specific chemicals or biological substances, or as a ranged sensor to
detect airborne molecules such as toxic gases or explosive vapors.
RR R W R W WW The main limitation of biosensors is that they don’t detect “unknown” com-
pounds. However, they can be easily updated by plugging in a new biosensor chip.
At TL8+, more sophisticated biosensors may work as “electronic noses” with blood-
hound-like odor detection capability. For an example of a biosensor, see the chem-
scanner (p. UT19).
12 BIOTECHNOLOGY
Optical Biochips (TL8) Heredity
Bacteriorhodopsin is a natural protein derived from bacteria. When illuminated, it
absorbs light and undergoes predictable and rapid chemical changes. (Continued)
Bacteriorhodopsin may be stabilized into two-dimensional lattice structures that func- Recessive traits can skip generations,
which is why you sometimes see chil-
tion as optical switching systems on a much smaller scale and with higher information
dren who don’t resemble their parents.
density than silicon-based electronics. Biochips using bacteriorhodopsin lattices or In humans, many rare traits, including
similar protein-based information technologies may provide the integrated computing most inherited genetic defects, tend to
power necessary for many TL8-10 gadgets, such as minidisks, computer chips, optical be recessive.
data storage, holographic technology, “rollable” video displays and datacloth (p. In practice, heredity is actually a lot
UTT32), miniaturized HUDs, cyberwear (especially bionic eyes), microbot brains (p. more complex than the “ideal”
RO67) and “smart” textiles such as varicloth (p. UT27), chameleon suits (p. UT85) Mendelian model – there are mixed-
dominant, cross-dominant and non-
and intruder suits (p. UT86). They are also a vital precursor to nanotech.
Mendelian traits that break the rules
Vatbrain Biocomputers (late TL8) described above. Some traits are also
“sex-linked” – that is, they are located on
sex chromosomes, and are transmitted
A vatbrain, or “meat matrix,” is a computer whose processing capabilities have
differently between males and females.
been enhanced with organic nerve tissue. Due to their ability to mimic human neur- In many science fiction novels that
al systems, vatbrains are highly efficient. The down side is that the life-support deal with psi abilities (notably Frank
facilities for their organic central processing units are heavy, requiring precise envi- Herbert’s Dune and Marion Zimmer
ronmental controls and nutrient feed systems. Some experimental models may be Bradley’s Darkover series), recessive
too delicate for commercial use, but spin-offs of biochip systems and cyberbrain and sex-linked traits are often used to
technology may remedy this. explain why certain psi powers are rare,
Vatbrains are constructed using the computer rules found on pp. CII12-15. or why women or men are more likely
to manifest them.
They must have the neural-net option. In addition, weight and volume are multi-
plied by 1.5 and cost is multiplied by 5. They have +1 Complexity.
A vatbrain of Complexity 7+ can spontaneously “awaken” and become sen-
tient. Roll 3d each year. On a 6 or less, the computer awakens; see p. UT31 or p.
Polymerase Chain
RO57 for the effects. A good example of a sentient vatbrain is Memnon-12 (p.
CW92-93), a TL8 macroframe with the neural-net and vatbrain biocomputer
Reaction (PCR) (TL7)
One of the basic tools in any genetics
options that has put extra character points into IQ and skills. lab since the late 1980s is the polymerase
chain reaction (PCR) machine. This can
DNA Computers (TL9) rapidly replicate (“amplify”) DNA from
very small amounts of source material in
This technology makes use of the amazing information density of DNA. By a matter of hours, creating thousands of
modifying its strands to form a half-dozen or so branches, “computing cells” can be copies of DNA fragments from single
linked together into a complex “bio-net” matrix. Data is then stored as electrons in cells. Besides its use in genetic engineer-
metallic atoms bonded to each cell. A DNA memory unit the size of a sugarcube ing, PCR allows genetic testing from as
could store terabytes of data, while cell-sized DNA computers could control micro- little material as a hair follicle or a tiny
bots or nanomachines such as the nanoviruses used in gengineering and nanosurgery. drop of blood (see Genetic Testing, p. 9),
permits the automation of gene sequenc-
Will DNA computers be the wave of the ing (hastening efforts like the Human
future, or will they be replaced by advanced Genome Project, p. 14) and allows
optical storage or inorganic nanocomputers? genetic reconstruction (p. 11), enabling
It would be reasonable to assume that TL9+ researchers to isolate and replicate
computers are DNA computers – and just as ancient DNA samples.
reasonable to assume that they use other One weakness of PCR is that it is so
techniques – so it’s up to the GM. However, sensitive, technicians must use great
care to ensure that whatever DNA they
if DNA computers do fulfill their promise, it are amplifying actually comes from a
would be quite realistic to increase the data particular sample, rather than contami-
storage of both “disks” and mass storage by nants – say, a skin flake from the
a factor of 1,000 – that is, read “gigabytes” researcher.
(gigs) as “terabytes.” Continued on next page . . .
BIOTECHNOLOGY 13
Polymerase Chain Cloning of Multicellular Organisms
Reaction (PCR) (TL7) Unlike bacteria, species that reproduce sexually receive chromosomes from both
parents, and each child is different. Cloning is a way around this. It is a bioengineer-
(Continued) ing technique that is used to produce multiple, genetically-identical offspring.
All late TL7+ genetics labs include Cloning is easy with plants – it’s done by making a cutting and planting it.
PCR machines or their ultra-tech equiv- Farmers and gardeners create clones all the time. It’s not so easy with animals, but it
alents. On their own, PCR machines is possible.
may cost from $3,000 to $125,000, Much of the current research into cloning is driven by its commercial potential.
depending on their speed and capabili- For example, a prize cow or a superior strain of wheat can be reproduced exactly.
ties.
Combined with gengineering, cloning allows genetically-engineered species to be
The Human mass produced, even if the gengineering was so extensive that they could no
longer interbreed with normal specimens. The uses of human cloning are dis-
Genome Project cussed on pp. 16–17.
Embryo Division (TL7): Another way to produce identical copies is to split an
The complete set of instructions for
making a particular organism is called
embryo at the 2-, 4-, 8- or possibly 16-cell stage to produce artificial twins, quadru-
its genome. It exists in the nucleus of plets, et cetera. While this isn’t true cloning, it is considerably easier to do. It has
every cell, and acts as the blueprint for been done with humans, but has little practical use.
all cellular structures and operations.
The Human Genome Project is an
international endeavor to discover the
50,000 to 100,000 human genes (the
human genome) and determine the com-
plete sequence of the three billion DNA
subunits (base pairs) that make them up.
The full project was underway by 1990.
The project was intended to be finished
around 2010, but recent advances in
automated gene sequencing and parallel
computing may result in early comple-
tion, between 2001 and 2005.
Currently, about 4% of the total
genome has been mapped. However, a
major preliminary part of the project
has been the development of technolo-
gies for rapid DNA mapping and
sequencing, and it is expected that as
these mature, the pace will pick up
Cloning from Embryonic Cells (TL7)
exponentially – which it seems to be Cloning technology was first explored in the mid-1960s with frogs and fish,
doing. It will be much easier to map the whose egg cells are very simple in design. These early clones were made by trans-
genomes of other animals. In fact, par- planting the nucleus (containing the chromosomes and genes) of an embryonic ani-
allel projects to do just that are already mal cell into an egg cell whose genetic material had been removed. With electrical
being carried out. stimulation, the modified egg then developed normally into an embryo, a fetus and
Conservative predictions involving
no new technologies suggest that the finally a baby, genetically identical to the nucleus donor.
completion (or even partial completion) However, while scientists could make clones, there seemed to be a catch – a
of the project will bring the ability to process known as cell differentiation. As an embryo develops into a fetus, certain
cure many or all genetic diseases via genes in each particular cell activate, depending on the cell’s role in the developing
gene therapy (p. 9). It will also allow organism. The cells become much more specialized; for instance, they turn into skin
very precise genetic testing, which may cells, heart cells, brain cells and so on. The unused genes “switch off,” and the now-
have considerable social impact (see specialized cells lose the ability to replicate in the fashion that cloning requires,
Genetic Testing and Privacy Issues, p.
10). Human genome mapping will also because the genes required to make a complete animal are no longer functioning.
make “DNA fingerprinting” much sim- The only way to avoid this problem seemed to be to take a cell from the early
pler and more precise, with major appli- embryo (a stem cell), before it had differentiated.
cations in forensics in particular and During 1980s and 1990s, cloning experiments were applied to mammals.
identification technology in general. Human embryos were first cloned in 1993, but they were not allowed to develop
In the long term, genome mapping is into fetuses. Researchers figured out how to make multiple clones by culturing sev-
a necessary precondition for advanced eral cells from the same embryonic cell, but this had limited usefulness. You could
genetic engineering. It is the key to
understanding the structure, organiza- clone animals like livestock, but because you’d have to start with the embryo, there
tion and function of DNA in chromo- was no way of knowing whether the animal would be worth cloning. As for cloning
somes. humans, you’d have to make the decision to clone before someone was born! There
Continued on next page . . . seemed to be no way to clone an adult, a child or even a fetus.
14 BIOTECHNOLOGY
Cloning from Post-Embryonic Cells (Late TL7) The Human Genome Project
This is adult cloning. Take a DNA sample from anywhere (skin, breast, blood,
et cetera), load it into an egg whose DNA has been removed, and grow it into a
(Continued)
baby who is a perfect genetic copy of the original cell donor. It seemed like an
impossible dream – but in 1997, Scottish scientists led by Ian Wilmut proved that
Genetic Differences
How similar are the genes of
the impossible wasn’t: Dolly, a female sheep cloned from adult cells, was born! humans and other animals? All mam-
How is this accomplished? mals have about the same number of
First, cells (in the case of Dolly, udder cells) are removed from an adult animal genes, about 50,000 to 100,000. Within
and allowed to replicate in nutrient dishes. Then, the nutrients are scaled back dra- the DNA sequence – the arrangements
matically, and the starving but still-living cells become quiescent. This crucial addi- of nucleotides – ape and human genes
differ by less than 10%. For non-pri-
tional step of making the cells inactive is enough to allow their genes to receive sig- mate mammals, like cats or mice, the
nals to start making an embryo, given the correct environment. difference is about 20-30% overall.
This environment is provided by an egg taken from a female of the same Physical differences are the result of
species (who can also be the cell donor). Using techniques similar to embryonic very subtle changes in the nucleotide
cloning, the nucleus of the unfertilized egg is scooped out, removing the genetic sequences that make up the genes.
material but leaving the rest intact. An electrical spark is used to fuse the quiescent These in turn produce somewhat differ-
donor cells with this egg, “awakening” the cell. The egg and nucleus then begin to ent proteins which interact with each
other, producing the cellular differences
form embryonic cells; about a week later, they’re ready to be implanted into a surro- that add up to spell “human,” “mouse”
gate mother. The offspring that results is a clone of the original cell donor, with no or “cat.”
relation to the egg donor or the surrogate mother.
While cloning of adult organisms is now a reality, there are still some real and
potential problems with the technology:
Inefficiency: The methods used to produce adult clones at late TL7 are very dif-
ficult and labor intensive. In Dolly’s case, out of 277 attempts to fuse adult cells
with eggs, only 13 pregnancies resulted, and only one was born alive. Nevertheless,
it seems likely that the odds will improve if further research and development are
financed. In GURPS, we assume that further research into cloning and artificial
wombs at TL8 will improve the success rate and reduce the cost.
Side-Effects: Adult cloning appears to produce an healthy organism, but it may
take years to be certain. For example, there has been speculation that the cells of a
cloned organism – taken from an adult – might “wear out” faster, resulting in pre-
mature aging. GURPS assumes this won’t be the case – or if it is, that it will be
overcome by more research. If the GM wants to use this concept, it could be simu-
lated by giving clones disadvantages such as Short Lifespan or even Self-Destruct
(p. CI104). If so, the age of maturity won’t be any lower, but afterward, aging will
occur more rapidly.
Sheep vs. Humans: Sheep embryos have some differences from human embryos
in their early development that may make them easier to clone. The method used to
clone sheep is expected to work on animals like cows, but it remains to be seen how
difficult it will be to clone a human using these techniques.
BIOTECHNOLOGY 15
who was malnourished during her pregnancy, the clone may well grow up to be both
Examples of taller and healthier!
If forced-growth tanks (p. 19) are available, they may be able to regulate the
Biomimetic Products fetal environment to ensure that a clone is identical in appearance to the original,
assuming this is desired. Without this technology, ensuring that a clone is complete-
ly identical requires ensuring that the clone’s nurture and environment – from womb
Two examples of biomimetic prod-
onward – simulate the original’s. In some cases, this may require exhaustive
ucts of use to adventurers:
research into the original’s childhood.
Light Arachnoweave PD 1, DR 4
(PD 0, DR 2 vs. impaling); $400, 0.5 lb.
Cloning Costs and Times
for vest; $500, 1 lb. for full suit. Today (late TL7), cloning is still experimental – some estimates place the cost
Medium Arachnoweave PD 2, DR 8 of making an embryonic clone at about $50,000–$150,000, while a post-embryonic
(PD 1, DR 2 vs. impaling); $600, 1 lb. clone (like Dolly) might cost $750,000. If cloning is commercialized, prices should
for vest; $800, 2.5 lbs. for full suit. drop dramatically. Suggested prices and times for cloning mammals are:
Heavy Arachnoweave PD 2, DR 12
(PD 1, DR 2 vs. impaling); $800, 1.5
lbs. for vest; $1,000, 4 lbs. for full suit. Post-Embryonic Cloning: At early TL8, a biotech facility will take 1d weeks
(allowing for failures) to clone a tissue sample, at a cost of $10,000 per week. This
As with Kevlar and monocrys, any 6
drops to a flat $1,000 and one week by late TL8, halved at TL9 and again at TL10.
rolled does one point of crushing dam- The result is a cloned embryo, which must be either implanted into a surrogate
age, even if the attack does not pene- mother or grown in an artificial womb, such as a growth tank or forced-growth tank.
trate armor. See Reproductive Technology (p. 17) for these procedures.
Embryonic Cloning: Divide the cost by five if cloning embryonic rather than
Biosensors – fetal, child or adult cells.
Chemsniffer (TL8) Assuming human cloning is legal, prices and times for cloning animals and
humans will be similar. At TL8+, many hospitals and biotech labs will be willing to
A hand-held biosensor system.
Devices of this sort are often used by bank a customer’s cell samples in a secure freezer for later use. This costs $100 a
customs officials or police to detect month.
contraband, such as drugs or explosives, While other GURPS books have coupled cloning technology with the idea of
by analyzing traces in the air. It’s typi- rapid growth (making an adult in six weeks, for instance), cloning and the forced
cally equipped with a range of biosen- growth of early embryos into adults are not the same technology by any means. At
sor chips for 100 standard chemical present, we know how to clone from adult cells, but the result is a baby – and the
compounds. Use Electronics Operation
(Security Systems) to operate it; the
technology for both artificial wombs and the rapid growth of embryos is likewise in
device has a five-yard range. If contra- its infancy.
band is completely sealed in airtight
containers, the sniffer will be ineffec-
tive; however, careless loading may
Cross-Sex Clones (TL8)
have left residues on the outsides of the Chromosome manipulation may be used to change the sex of a clone, while
containers. A chemsniffer costs $700 keeping it more-or-less identical otherwise. At mid-TL8, this takes about a week of
and weighs 2 lbs. It operates for 6 effort and costs $20,000 for a male-to-female change or $70,000 and an extra two
months on a B cell. weeks for a female-to-male change (this requires the creation of an artificial Y chro-
mosome, which is tricky).
16 BIOTECHNOLOGY
Monoclonal
Antibodies (TL7)
These are a good example of a “bio-
product” produced by gengineering.
Ordinary antibodies are manufactured
by specialized “B-cells” in the lymph
nodes (including the spleen) and the
Clones as Spare Parts blood. They are a vital part of the
body’s immune system, seeking out and
One difficulty with transplants (p. 65) is the problem of tissue rejection. If attaching themselves to intruders such
human clones can be grown, they could be used as a source of medical transplants as microbes, viruses or foreign proteins.
for the original, with no chance of rejection. (This also applies when transplanting This alerts the rest of the immune sys-
parts from the original to his clone, as in a brain transplant.) tem (white blood cells, for instance) to
One clone can provide a complete set of organs. These can be left in the clone attack.
There are millions of different kinds
(with it gradually going over to life support as more bits are removed) or removed of antibodies. Each is specialized to
and preserved separately. The most radical procedure would be to transplant your detect one particular type of unwanted
adult brain into a younger clone body, or better still, use mind transfer technology organism. Antibodies are carried along
(see Braintaping, p. 116) to upload your memories from an aging body into that of in the bloodstream, ignoring everything
young clone of yourself! else until they run into their targets.
In some societies, the ethical issues of growing humans for spare parts may pre- They recognize them because each mol-
vent this technology from being developed. In others, it may be enough to simply ecule has its own particular, unique
physical contour. Each antibody is
keep a person’s clone comatose, or lobotomize it, so that its mind never develops. shaped to match puzzle-fashion with its
Even so, the cost of making a clone and maintaining it on life support is high – target molecule, so that when they acci-
see Cloning Costs and Times, above, for the cloning operation itself, and Growth dentally run into one another, they will
and Forced-Growth Tank Fees (p. 20) for the cost of actually growing or maintain- lock together.
ing a clone. Thus, this technology may be something that only the rich can afford, Recently it has proved possible to
unless society itself gets wealthier. This could lead to a two-tiered medical system, clone specific antibodies outside the
where the wealthy use cloned organs (or high-end bionic parts) and the poor use human body, using genetically-modi-
fied cancer cells (“hybridomas”). What
each other as tissue donors. good are these “monoclonal antibod-
ies”? Not much on their own. However,
Vat-Grown Organs and Parts they can be further modified for various
special tasks . . .
While growing a clone as a source of spare parts may be too ghoulish for soci-
ety to contemplate, there is an alternative. Advances in tissue engineering may
make it possible to grow organs from cell cultures in vats or on biodegradable scaf- Monoclonal Antibody
folds, without the need to clone an entire human. Initial developments in tissue
engineering should enable kidneys, livers, ears, noses and possibly genitals to be
Applications
vat-grown by early TL8, taking about four weeks. However, independently growing Diagnosis: Vat-grown monoclonal
antibodies can have fluorescent or
other organs and body parts (like hearts, lungs, eyes and limbs) is more complex,
radioactive molecules bonded to them
and may require “whole body clones” until late TL8. This means that an organ when they are created. When added to
shortage may still exist. For more details (prices, et cetera) on organ replacement, blood, they will find the specific pro-
see Medical Transplants (p. 65) and The Organ Trade (p. 129). tein, virus, et cetera, that they are
designed to target, and bond with it. A
Reproductive Technology
So the bioengineer has performed germline gengineering, or has just finished
blood sample can then be taken and a
filtration process used to wash away any
antibodies that aren’t attached to some-
thing. If any light or radiation is still
cloning. What next?
emitted after the wash, it means that the
If his subject is a microbe, plant, or egg-laying amphibian, fish, reptile or bird, antibodies have found whatever they
it’s pretty easy. All he needs is a petri dish, some soil, a pond or an incubator like were sent to find. This process is being
those used for chickens. However, higher animals that bear live young have special used today, and promises rapid but
requirements. If that genemod egg sitting in a test tube is to grow past the stage of accurate medical diagnosis. At TL8+,
an early embryo, into a fetus or beyond, then it’s going to need the right environ- wide-spectrum tests using monoclonal
ment – a womb. antibodies are standard in clinics, diag-
There are two major choices here. First, the egg can be implanted into a living nostic beds, automeds and hospitals.
being – a surrogate mother (maybe the original mother, if the egg came from her
before modification). Second, it can be brought to term in an artificial womb. Continued on next page . . .
BIOTECHNOLOGY 17
Monoclonal Surrogate Motherhood (TL7)
A fertilized egg or early embryo can be transferred to a human host mother to
Antibodies (TL7) grow to term within her. This has the advantage of not requiring a bulky, ultra-tech
(Continued) growth tank (see below). Some people believe it might also be better for the mental
or physical health of the child. The disadvantage is that surrogate motherhood, espe-
Target-Seeking Drugs: Treatments cially for pay, is often considered unethical and illegal, and hence can be expensive.
such as chemotherapy release toxic In areas where the practice is legal, a host mother can be hired for about
chemicals, intended to kill cancers, into $20,000 plus payment of medical bills. Usually, a potential mother has to undergo a
the body. Unfortunately, they also poi- medical exam to certify she is healthy, and sign a contract agreeing to refrain from
son the body, and selecting a dosage certain activities (e.g., substance abuse, dangerous sports) that might put the devel-
that will kill cancer but not the host is oping child at risk. In some areas, professional associations of surrogates may exist.
very difficult. By bonding drugs to If surrogate motherhood is illegal, the fee could be much higher. Cheaper host
monoclonal antibodies, far more toxic
chemical scan be used in much smaller mothers could be hired in impoverished regions, such as slums or Third World
amounts, because the antibodies deliver nations. However, many employers might balk at this, partly due to fears that a des-
the chemical directly to the target cells. perate and impoverished mother might be more likely to suffer from ill health or
This is like the difference between “car- substance abuse, and partly due to genetic snobbery.
pet bombing” and a “smart” bomb: the There is some chance that the mother will become attached to the child and try
first may kill a lot of innocent victims to keep it, or change her mind and decide to terminate the pregnancy. This risk is
without doing the job, while the second increased where surrogate motherhood is considered illegal, since there is little the
takes out the target with minimal collat-
eral damage. Aside from smart-bomb- employer can do in such circumstances without admitting guilt. In any such disputed
ing cancers, monoclonal antibodies can circumstance, the exact legal status of surrogate motherhood, and the nature of the
be used as the targeting system for other transaction involved, will usually influence the decisions of the court in determining
drugs, guiding various chemicals direct- whether the rights of the host mother, the employer or the developing fetus take
ly toward specific proteins. Many of the precedence.
“wonder drugs” described in GURPS Assume that a pregnancy at TL7+ goes as planned if the mother successfully
Cyberpunk, Space and Ultra-Tech use makes a (HT+TL) roll. If the mother’s roll fails, roll against the Physician skill of
monoclonal antibodies.
Other Uses: Vat-grown monoclonal the attending health care provider, at -5 if the mother had a critical failure. If this
antibodies essentially permit the bio- roll succeeds, the baby and mother are fine, although the baby may be born late or
chemical equivalent of finding a needle premature. If this roll fails, separate Surgery rolls should be made to save baby’s
in a haystack. This makes them useful and mother’s life. Use the normal Surgery rules (p. B56), with a -5 modifier if the
for a wide variety of industrial and med- Physician roll was a critical failure. Failure on the baby’s roll will kill it; failure on
ical processes, such as refining exotic the mother’s roll does 2d damage to her (4d damage on a critical failure), and may
proteins, creating “diagnostic bed” sen- cause sterility (see p. CI84) if she fails a HT roll. The surgical team can opt to put
sor systems, and consumer products,
such as . . . either mother or baby at greater risk in order to save the other; if so, add a bonus of
Continued on next page . . .
up to +3 to the Surgery roll of the favored patient in exchange for a matching penalty
to the other’s Surgery roll.
If the mother is carrying a genetically-modified baby that is of
unusually large size or has a partially non-human biochemistry (espe-
cially the Unusual Biochemistry disadvantage, p. CI106), a penalty of -1
to -8 can be applied to HT and Physician rolls.
If the mother was exposed to a mutagenic source (radiation, chemicals,
et cetera), addictive drugs or excessive amounts of alcohol during her preg-
nancy, roll vs. her HT. A failure means that the baby suffers from a -1 or -2
to ST, IQ or HT, an Addiction, or other physical or mental disadvantages
(GM’s option). Critical failure means that it suffers these problems and is
born Terminally Ill (p. CI84). Success means it survived and is healthy.
Critical success might mean a favorable mutation, if the GM wishes.
Adventure Seed – Rosemary’s Bioroid: A surrogate mother is expect-
ing a baby. A few weeks before giving birth, she changes her mind and
decides to keep the child, fleeing to a region where surrogate mother-
hood is illegal. What she doesn’t know is that she’s carrying a combat
bioroid instead of a human infant – part of a corporate (or even criminal)
“black program.”
18 BIOTECHNOLOGY
underway in the 1990s; they should be available in the early 21st century. The main
impetus driving this technology is not so much the desire to do away with the womb
as the need to create incubators that will enable very premature babies to survive.
Monoclonal
Currently, babies born less than six months after conception have little chance of sur- Antibodies (TL7)
vival, because their lungs aren’t ready to breathe air. Artificial wombs that use oxy-
genated fluids such as perfluorocarbons can enable much younger infants to survive,
(Continued)
and may lead to actual growth tanks in early- to mid-TL8.
An artificial womb contains the necessary facilities for growing a multicellular Disposable Test Kit (TL8)
animal (like a human) from gametes to healthy adulthood without their leaving the A cigarette-sized plastic vial. The
tank, eliminating the need for surrogate mothers. Growth tanks may be used to user pricks his finger on the included
grow clones, genetic constructs or unmodified human embryos. This is no faster needle, lets a drop of blood fall in,
than natural growth – growing a human from germ cells to a baby would require shakes and squeezes to break the mem-
brane. If the vial glows a particular
about nine months; growing them to adulthood would require 18 years. color, he tests positive. No skill is
Growth tanks may be enclosed, but are often transparent so that observers can required to use it, but each kit tests for
see the developing organism. They are big enough to allow the organism within to one specific thing. Kits are available
grow to adulthood. that test for various common and not-
An organism developing in a growth tank has the same degree of awareness as a so-common diseases, from AIDS and
baby in its womb. Individuals kept in the tank past the fetal stage and into childhood other sexually transmitted diseases, to
will be conscious, but will not develop mentally in the absence of stimuli. Electrodes various types of influenza, to cancer.
Others can be designed to detect preg-
attached to muscle groups can keep them stimulated in the tank, the body twitching nancy, malnutrition or the use of a spe-
constantly in an unconscious exercise program that maintains muscle tone. cific drugs. Military-issue kits may test
It is safe to remove a creature from the tank before its intended “birth” date, for various biochemical weapons. A
provided it has developed past the fetal stage. If the organism has been in there for genetics lab is needed to design new
less time, it will not be able to survive outside the tank without medical care (and test kits – and of course, kits will only
prompt transfer to another growth tank or surrogate mother). be available for testing known diseases,
Destroying a growth tank (e.g., smashing it) and severing the artificial umbili- drugs, et cetera. 2 oz., $5. LC 6.
Civilian test kits may be available from
cal cords will free the organism. This will kill it if it has not developed enough to be vending machines.
born, but is probably not significantly more traumatic than a normal birth otherwise. At TL9+, monoclonal antibodies are
A growth tank designed for a human-sized organism is 250 lbs., 50 cf and supplemented by tailored nanomachines
$200,000. It runs on building or vehicle power (0.1 kW). Cost (only) is halved at that perform similar tasks with even
TL9 and again at TL10. At TL12, advances in biotechnology allow the creation of more precision.
much smaller and cheaper portable growth tanks that are only 100 lbs., 20 cf and
$5,000. These can run for a year on a D cell. All growth tanks require a Complexity
4+ computer to monitor life support. In Vitro
Normal growth tanks can be used to grow any single organism of up to human
size (two hexes when standing). For larger growth tanks (e.g., for horses or
Fertilization (TL7)
dinosaurs), multiply the weight, volume, cost and power requirement by the size in In vitro (“in glass”) fertilization
hexes an adult will occupy. allows pregnancy without sex. A
female’s eggs are fertilized with sperm
Forced-Growth Tank (Late TL8) in a laboratory dish, and the resulting
embryo is implanted into her uterus,
Also known as a “zoom womb,” this is a growth tank equipped to tremendously into that of a surrogate mother or – at
accelerate the development of the organism within it without doing it any harm. TL8+ – into an artificial womb such as
At present, forced-growth tanks are very much science fiction; no one knows a growth tank or forced-growth tank.
how to make them. However, without forced-growth tanks, many of the dramatic Today, in vitro fertilization (IVF) is
possibilities of cloning are rendered moot due to the time it takes a human being to a relatively common but somewhat
develop to adulthood. With a forced-growth tank, it is possible to take a cell sample tricky and expensive procedure. In
humans, each attempt costs about
from someone, make a clone and force-grow it to maturity, or even the same age as $5,000 at TL7. Divide the cost by 5 at
the cell donor, effectively allowing the creation of clone doubles. It’s also possible TL8, and by 10 at TL9+. There is only
to mass produce armies of cloned or genetically-altered people. about a 1-in-6 chance of success per
A forced-growth tank is identical to a growth tank, with the exception that the attempt at TL7 (each attempt takes at
organism within it develops much more rapidly. A forced-growth tank takes a mini- least 4d weeks); at TL8+, this chance
mum of three weeks to mature a human from a cell into a baby that can survive out- increases to 5-in-6.
side the womb. If not removed from the tank, the growth can then be accelerated to One advantage of IVF is that it
makes it possible to perform very early
the even more rapid pace of just over one physiological year per day until the genetic testing. If genetic problems are
organism reaches age 25. suspected (e.g., the mother or father was
The force-growth process can be deactivated, allowing the person to grow in a exposed to mutagenic chemicals or had
normal fashion, exactly as within a growth tank. Once it is stopped, it cannot be a history of genetic defects), IVF may
restarted without killing the organism. Alternatively, the organism can be “stabilized” be preferable for this reason alone.
BIOTECHNOLOGY 19
using an artificial hibernation process to keep it unconscious and at the desired
physiological age for as long as it remains in the tank.
Deep Learning (TL9) While someone is being force-grown, he is unconscious. A person newly awak-
ened from a forced-growth tank is a blank slate, with no memories or skills.
This future (TL9+) technology is
often used in conjunction with forced- A forced-growth tank designed for a human-sized organism is 250 lbs., 50 cf
growth tanks. Deep learning is an inten- and $1,000,000. It runs on building or vehicle power (0.1 kW). Cost (only) halves at
sive process that works on a “blank” TL9 and again at TL10. At TL12, advances in biotechnology allow the creation of
brain (one with no prior experiences much smaller and cheaper portable forced-growth tanks that are only 100 lbs., 20 cf
outside an artificial womb), making and $10,000. For larger tanks, multiply the weight, volume, cost and power require-
extensive use of technologies such ment by the size in hexes an adult will occupy.
a s sleep-teaching tapes, learning- Note: Forced-growth tanks are referred to in most other GURPS books as
enhancing drugs, virtual-reality sessions
and (at TL10+) neural-interface “clone tanks.” The tanks actually have nothing to do with cloning per se; they are
“dreamgames” to program someone simply the means by which a clone can be rapidly grown to a useful age.
with a synthetic set of skills and knowl-
edge.
Six weeks of deep-learning “social-
Growth and Forced-Growth Tank Fees
ization” can give someone basic life An institution that provides growth tank services will usually charge the follow-
skills. This can take place while a ing fees to its customers:
person is growing in a growth or fast- • $1,000/month to grow an embryo in a growth tank (or a forced-growth tank
growth tank. Deep-learning socializa- without using forced-growth). Growing a human embryo to a baby would thus cost
tion training gives the subject control $9,000 and take the usual nine months, while leaving him in the growth tank and
over his own body and the ability to growing him to age 25 would cost a further $300,000 and take 25 years.
understand and speak one language at
• $1,500/week, for six weeks, to force-grow a human to maturity (or to any ear-
IQ level.
Up to an extra year and a half (more lier stage of development).
time imposes too severe a psychological For species that mature earlier or later, modify the times and costs appropriately.
stress) can be spent in deep learning. For larger-than-human organisms, multiply the cost by the size in hexes. However, the
Every month allows two character only places likely to be set up for growing large organisms are major biotech corpora-
points to be spent on skills. Thus, some- tions. Persuading them to tie up their facilities requires either a very large advance
one who came out of the tank after 18 order, inside connections or a substantial additional fee of perhaps 10 times the cost.
months could spend 36 character points
on skills, much like an 18-year-old
human. Chronowomb (TL15)
Continued on next page . . . A chronowomb is similar to a forced-growth tank, except that instead of using
chemicals to accelerate growth, it creates a miniaturized pocket of accelerated time
within the tank. Typical chronowombs produce about 700:1 time dilation –
about a day of growth every 2 minutes, a month every hour, or 2 years every
day.
External controls allow the chronowomb to be set to operate for a specif-
ic amount of time. When not being used in chrono-acceleration mode, it
functions as an ordinary growth tank.
Unlike forced-growth, developed individuals (or even adult humans) can
use chronowombs – but they should be careful with the setting or they may
end up aging to death! A side effect of the time-acceleration process is disori-
entation followed by unconsciousness: individuals can’t climb into a
chronowomb and study skills or the like, although they can use it to heal
(regenerating about 1 hit per 2 minutes).
A chronowomb built for a human-sized occupant is 500 lbs., 100 cf and
$1,000,000; halve weight and volume, and divide cost by ten, at TL16. A
chronowomb requires at least 10,000 kW of power and usually runs off
building or vehicle power. For larger tanks, multiply the weight, volume, cost
and power requirement by the size in hexes an adult will occupy.
Optionally, chronowombs may appear before TL15, if lower-TL time-
manipulation or time-travel technology also exists. Fees for using a
chronowomb are typically $1,000 per hour of “real time.” For larger-than-
human organisms, multiply the cost by the size in hexes.
Biotech Facilities
Gengineering isn’t something that can be done on the kitchen table –
specialized equipment is necessary.
20 BIOTECHNOLOGY
Lab Facilities
These are necessary to fulfill the basic equipment requirements for
genetic engineering tasks. Weight and cost are not reduced at higher TLs –
instead, sophistication increases. Modifiers are given for both minor and
major tasks. “Minor” tasks are things like genetic testing, or synthesizing a
known protein. “Major” tasks include cloning, chromosome mapping and
sequencing, genetic reconstruction and genetic engineering.
BIOTECHNOLOGY 21
Lifebanks and Genome Libraries (TL7)
Hellkitchen (TL8) A lifebank is an indexed collection of seeds, eggs or embryos. A well-stocked
lifebank will have examples of many different genotypes within a particular species,
This is a suitcase genetics lab (p. to ensure genetic diversity. About 50 individuals per species would be the minimum
21) optimized for producing biological breeding populace needed to allow that species to be reintroduced successfully,
weapons. It contains the necessary pre- while 1,000 could preserve most of a species’ genetic diversity.
cision scientific equipment (including The simplest stable ecosystems (e.g., an isolated lake) might have under 1,000
a miniaturized gene-splicing and PCR
species, but most have 10,000 or so. Earth may have as many as 80 million species –
machine), cell cultures and genetic
engineering computer software to 2-4% of all the species it has ever had. Extensive lifebanks may be established as a
transform an ordinary kitchen into a safeguard against extinction. At higher TLs, they can be found aboard colonizing
biowarfare laboratory. A hellkitchen “seedships.” Lifebanks require $500, 5 lbs. and 0.1 cf per embryo stored. A live bac-
gives -2 to skill on minor tasks, and a -8 terial culture, or large quantities of germ cells (hundreds of human gametes, plant
penalty when working on major pro- seeds or bacterial spores), can be frozen for the same amount of weight, space and
jects – with the exception of disease money.
cultures and similar bio-weapons,
A genome library stores the data for a mapped and sequenced genome in digital
where the penalty is only -5. It can also
manufacture additional doses of a germ form. This information can then be used to synthesize DNA, although growing a
from an existing or modified culture at complex organism like a human with nothing but a digital genetic code requires
a rate of one dose per hour; an unmodi- TL10+ technology and is far more time consuming than if actual samples existed.
fied skill roll should be required to set (See Genetic Reconstruction, p. 11). A complete genome database (plus Complexity
this up. 2 indexing programs) for a particular species genome is $5,000 (and 5 gigs) for
The hellkitchen is so compact microorganisms or plants and $20,000 (and 20 gigs) for other life forms.
because it lacks even rudimentary safety
features; any critical failure results in
some form of disaster (e.g., the user
becoming infected or releasing a
Other Biomedical Facilities
plague). This applies whether trying to
modify a disease or find a cure for one. Containment Tubes (TL8)
In its suitcase-sized package, the hell- These resemble giant, vertical test tubes, large enough for a person to stand
kitchen weighs 20 pounds and costs upright in, resting atop a base platform containing a life-support system and power-
$50,000. Packing or unpacking it takes ful vacuum pumps. They are used for containing human-sized specimens. In a
10 minutes. GURPS Supers campaign, any real mad scientist’s lab will have a few of these for
holding captured superheroes or experimental specimens.
The tubes are sealed, but are connected to an external air conditioner that recy-
cles the air within them. They can also be pumped empty of air in 30 seconds.
Canisters may be attached to the tubes to allow gases or liquids to be pumped into
them (e.g., sleep gas, nerve gas, germs or proteus virus), or to maintain a different
atmosphere within the containment tube. A gas canister suitable for flooding the
tube (requires five doses of whatever gas or other agent is used) is 5 lbs. and $300.
It can hold 100 doses of gas.
Access to the tube is provided by a transparent sliding door, which causes part
of the tube to slide open. The door’s lock cannot be picked from inside the tube.
Opening or closing the door, or controlling life support in the tube, is accomplished
using either controls on the base or an external computer terminal. The containment
tube itself is made of a plexiglass-like material with DR 30 and 20 hit points. Add
10 to DR per TL over TL8.
Each containment tube is $6,000, 300 lbs. and 15 cf. It runs off building power
(0.1 kW). For double cost, the containment tube can have twice the DR; at four
times cost, three times the DR. Containment tubes for beings larger than humans are
possible; multiply cost, weight, volume and power requirement by relative hex size.
Growth tanks, forced-growth tanks and chronowombs may be outfitted as contain-
ment tubes; add half the weight, cost and volume of the tube to the weight, cost and
volume of the growth tank or womb. This is useful if growing dangerous beings.
Cryocase (TL8)
This is a portable cryogenic storage case, normally used for transporting organs,
frozen embryos or similar fragile biological cargoes. Its interior can be configured to
contain a human head or arm, up to three large organs (heart, kidney, et cetera), or
twice that many smaller organs (eyes, for instance). It will preserve them for as long
as it has power, after which they will spoil within 1d hours. The cryocase is also suit-
22 BIOTECHNOLOGY
able for transporting other products that need to be frozen – evidence samples or cer-
tain drugs, for instance. The case is about the size of a large suitcase. When empty, it
weighs 10 lbs. It costs $2,000. A single C cell powers it for 24 hours, or it can be
Chrysalis
hooked up to building power (negligible requirements) to run indefinitely. Machine (TL13)
Portable Brain Pod (TL8) The ultimate in biomedical technolo-
gy, a chrysalis machine is a medical
This is a portable suspended animation unit that is specifically designed to keep device designed for nanotechnological
a disembodied brain (and portion of the spinal cord) alive. It is used for the trans- repair and transformation. It is a coffin-
portation of disembodied brains, generally prior to a brain transplant or total cybor- sized or larger machine that the user
steps into or is placed within. The
gizing operation. It can also be used for long-term storage. machine then spins a life-support web
A portable brain pod does not include the systems needed to keep the brain around the patient, completely enfold-
conscious, or any neural connections that would allow the brain to operate equip- ing him. Each cell is surrounded with
ment such as neural interfaces, communicators or sensors. (In fact, it includes sys- microscopic biological repair and sup-
tems designed to keep the brain unconscious, as a conscious brain would suffer total port machinery, which takes over con-
sensory deprivation, which could damage its sanity.) This is very deliberate, as it trol from the patient’s own DNA. The
allows the brain to be quickly and relatively cheaply installed or removed from the chrysalis instructs the cells to begin
self-repair procedures, and if necessary,
pod without the extensive and very expensive surgery required to make such con- takes the patient apart cell by cell and
nections. This is why placing a brain in a portable brain pod is much cheaper than rebuilds him in accordance with its own
transplanting it into a human body (p. 66) or cyborg body (p. RO52 and p. UT106), programming.
or keeping it conscious in a permanently disembodied state (p. P98). A chrysalis can heal almost any
A portable brain pod is 80 lbs. and $40,000, including a D cell power supply wound. Normal HT loss is restored at 1
(good for up to a month; a spare socket allows one cell to be removed while another HT per hour. Crippled body parts or
is still operating) and a casing. Weight and cost are halved at TL9 and again at missing fingers or toes are regenerated
in 24 hours; missing organs or limbs
TL10. It uses negligible amounts of vehicle or building power. regrow within a week. This is slower
Safely transferring a brain from a living body to a brain pod requires a well- than a regeneration field (p. UT104),
equipped TL8+ hospital, TL9+ automed or TL13+ chrysalis machine. Most hospi- but much safer! On a successful
tals will charge about $10,000 at TL8 for this service. The operation takes six hours Physician-2 roll, the time can be halved
to perform. If a character wants to try it, it requires a successful Surgery-5 roll, with (12 hours, or three days for a missing
failure resulting in a transplant to the pod but brain damage of some sort – such as a limb); failure means it takes the normal
permanent loss of 1d points of IQ – and critical failure resulting in death. time, critical failure may have perilous
side effects.
Transplanting a brain from a brain pod into a full cyborg body (p. UT106), total A person who is dead, but who has
cyborg body (p. RO52) or organic body has its normal cost. However, it takes only not suffered serious brain injury, can be
80% as long, and any skill rolls the GM requires to perform the operation are +2, restored to life. Roll against Physician,
since part of the work is already complete. at -2 for every hour the subject has been
dead. Success restores the patient to
life; failure by 1 or 2 indicates recovery,
with personality intact but substantial
memory loss (equivalent to Partial
Amnesia, p. CI86). Failure by 3+ also
restores him to life, but as a blank-
minded clone, with no memory or per-
sonality. A person who has suffered
severe brain damage can still be
restored, but only as a blank-minded
clone.
Beyond that threshold, if there are
Portable Microsurgery (TL8) some cells left, the chrysalis can
clone the original (the body may be
This is a compact microsurgical operating theatre, optimized for performing trans- totally crushed or burned, but not dis-
plants and neurosurgery (see Chapter 3), as well as modifying, repairing, removing integrated). The chrysalis machine
and installing bionics. It is small enough to fit in a room, trailer or van, and contains functions exactly like a forced-growth
enough tools to allow two medics to work at the same time. It adds +3 to Surgery, tank (p. 19). The result will be a
Diagnosis, Electronics or Electronics Operation rolls related to microsurgical tasks. blank-minded clone, unless a brain-
tape is available.
This sort of setup is favored by splicers (p. 129) and organleggers (p. 129), A chrysalis machine can also be used
since it can be packed up if the law comes calling. Security and intelligence agen- to transform someone, performing safe,
cies, and military units that use a lot of cybernetics, will also have a few of these fast clinical metamorphosis (see p. 79)
installed in vehicles (or safe houses), both for treating their own agents and for in conjunction with a metamorphosis
operating on defectors or prisoners – removing or inserting implants. nanovirus.
The portable microsurgery weighs 500 pounds and costs $30,000. It requires A chrysalis machine costs $150,000
about 25 cubic feet of space, or 10 cubic feet when packed for storage. and weighs 1,100 pounds. It takes up 75
cf and uses 0.1 kW of power.
BIOTECHNOLOGY 23
2 HUMAN GENETIC
ENGINEERING
“What a piece of work is a man! how noble in reason! how infinite in faculty!
in form and moving how express and admirable! in action how like an angel! in
apprehension how like a god! the beauty of the world! the paragon of animals! And
Defining “Human”
yet, to me, what is this quintessence of dust?”
What is “human”? This is a philo-
– Hamlet, William Shakespeare sophical question, but it may also be an
important legal and social one in many
Everyone thinks that they’re the end product of evolution – T. rex probably campaign settings. Definitions could be
thought that way just before he saw the comet flash. But with genetic engineering, based on the amount of human vs. non-
we can take control of our own cells, making our children brighter, faster and human DNA (i.e., “eugenic vs. species
immune to hangovers. We can even redesign people to live in space, so the next modification”). Other common criteria
time some big rock hits, some of us won’t be here. include:
Gengineering at Conception
A genetic engineer can insert recombinant DNA or RNA into a newly-fertilized
set, such as being physically indistin-
guishable from a normal human or,
perhaps more loosely, having a gener-
human egg cell (a zygote) to alter its genes. Those genes will express themselves by ally humanoid appearance.
Birth: This might exclude “non-
producing somewhat different proteins. As the zygote develops into an embryo and borns” who came out of incubators or
then a fetus, the new proteins will make up different cells, and a child will be born clone tanks, as opposed to “test-tube
with traits it would not have possessed had it remained unmodified. These changes babies,” conceived artificially but ges-
will be passed on to its descendants. This process is known as “gengineering at con- tated inside a surrogate mother.
ception,” or more technically, germline genetic engineering. Intelligence: A racial IQ modifier of
-3 or worse might disqualify someone
as legally human.
Eugenic Germline Gengineering (TL8) Theology: Belief systems may have
their own criteria, related to things like
“We’d like our Katiana to be petite and beautiful, with big, violet eyes and jet- the presence or absence of a soul, or
black hair. Could she have a tendency toward musical aptitude, with long fingers whether the person fits a definition of
for playing the piano? We also want her to be good at sports – an athletic body type man in a religious text.
would be nice, so she could be a gymnast. Oh, and we want the standard features,
of course: boosted immune system and genefixed heredity.
“Now, how much will all that cost?”
– Mr. and Mrs. Arlington
Sex Selection
“Of course a boy! We must have a
“Ever since my teens, I’ve really wished my parents had designed me for some- male, so he can marry and inherit the
thing practical. At least I don’t get sick.” family business.”
“You want a boy, she wants a boy . . .
– Katiana Arlington III
If every parent is going to have boys,
who are they going to marry?”
This is what most people think of when they hear the term “human genetic
engineering.” This is the process of selecting gene combinations that ensure the This is chromosome manipulation
appearance of traits the gengineer considers desirable; for example, good looks, rather than gene manipulation. Sex
high intelligence or perfect vision. selection is simply a matter of choos-
The abilities and disabilities of each of us result from traits inherited from a mix- ing whether the baby will have XY
(male) or XX (female) sex chromo-
ture of our parents’ genes, modified by environmental factors such as diet, experi-
somes. (If anyone wanted, such tin-
ence and education. Eugenic gengineering (“eugeneering”) involves determining kering could also result in a natural
what genetic combinations favor certain traits, then using gengineering at conception hermaphrodite.)
to make it likely they appear. It does not add anything new to the human genome, so Sex selection is easy, as genetic
a eugeneered person will still appear perfectly human to genetic tests or scanners. engineering goes, but may have pro-
The major stumbling block in the road to eugenic modification is that desirable found effects on society. For example,
traits can result from the interaction of hundreds of different genes. Moreover, one if parents favor boys over girls (as in
many Earth cultures), the result could
gene may be involved in multiple traits – change it to produce one effect and there
be a demographic disaster within a
may be unintended consequences for the others. generation, especially if population
The capability to perform eugeneering rests on possessing a complete map of controls restrict families to one child
the human genome (see The Human Genome Project, p.14) and a detailed under- each.
standing of how specific gene sequences affect human development. Completing a At TL8, sex selection costs $1,000 if
racial genome map is a TL8 achievement, and the ability to use this knowledge to it’s the only genetic modification
perform complex eugenic selection is TL8+. ordered; it’s free with more extensive
gengineering. Halve the price at TL9
Efforts to determine the effects of specific, modified gene sequences often pro-
and again at TL10+.
ceed by tinkering with the DNA of individual genes one at time, using animal sub- See also Cross-Sex Clones, p. 16.
jects. Since mammals such as mice share much of our DNA and produce successive
generations in a short period of time, animal testing can provide considerable
HUMAN GENETIC ENGINEERING 25
insight into the effects on humans, especially if the test animals are gengineered to
possess additional human genes. As more data is gathered on each gene’s role in
Sex and Genetic human development, computer simulations may supplement or replace experimenta-
Engineering tion, making eugenic selection far more practical, and allowing a designer to work
with a standard “tool kit” of genes known to produce certain effects.
Once this capability is achieved, eugeneering can create “designer people”
“I have my first Daddy’s hazel eyes whose potentials are enhanced or skewed toward a specific physical or mental ideal.
and my second Daddy’s red hair, but
they bought my sense of direction from Changes may range from the obvious (good looks, muscular build, 20/20 vision or
the gene bank.” “double-jointedness”) to the subtle (higher IQ, gengineering of the adrenal glands to
– Chance Mackintosh give someone a positive stress response).
At TL9, same-sex partners can use
genetic engineering to blend their genet-
ic material together. Women don’t need
Germline Gengineering for Species Modification (TL9)
to involve men at all; men will still need “Yesterday, the Mokoto twins started laughing and teasing me ’bout my gen-
a female egg donor, although the genet- emods again, calling me Girl Dracula and stuff. I bit one of them, but she beat me
ic material from the egg nucleus could up – ain’t no room to fly in the ship; it’s hard to fight back proper when your bones
be removed and replaced with genetic aren’t strong as theirs. I can’t wait for planetfall on Darktree. Soon we parahuman
material drawn from the male partners. kids be gliding from tree to tree, while them crew-brats be stumbling around in the
Splicing genetic material from same-sex
partners together costs an extra $10,000
groundfogs in their chillsuits and respirators. Then we see who’s laughing.”
and takes about a week. Halve this at – Tizbeth Sung-Morton (age 9), Darktree Colonization Fleet
TL10 and again at TL11+.
Species modification involves gengineering for complex traits that never existed
within the human genome, such as gene sequences that produce modifications to
Linked Advantages human anatomy. Some changes may be internal, like a modified liver that’s better
able to filter toxins. Others might be obvious, like a coat of fur or a pair of functional
and Disadvantages extra arms. Again, the main difficulties lie in predicting how the effects of a specific
genetic change will cascade over the entire genome, and in making major changes in
Sometimes, the genes that combine hundreds or thousands of genes at once. The tools to do this become available at
to produce a specific desirable trait are TL9 – megacomputers for running extremely complex genetic simulations, and
mingled with those of other traits. GMs bio-nanotech, such as highly-sophisticated, tailored retroviruses or nanoviruses.
can rule that this is the way it works for Gengineers might synthesize genes for totally new abilities,but it may be easier
specific advantages, requiring them to to enhance existing human traits, or design non-human abilities by basing them on
be combined with disadvantages, dis- the genes of terrestrial animals. This can be background information (“I’m part
tinctive features or even other advan-
tages. This has considerable basis in
bat?”) or imply colorful physical features (someone whose bat DNA sequences give
reality, and is very common in science them sonar and wings may have other chiropteran features, such as fangs and
fiction – what if an exotic advantage pointed ears). These may be the unintended results of cross-linked genes, or neces-
(like Intuitive Mathematician or a psi sary for a given trait (e.g., pointed ears for ultrasonic hearing).
power) were linked to a disadvantage This sort of transgenic gengineering is already in the experimental stage at TL7,
like Albinism or Short Lifespan? with single human genes having been inserted into “pharm animals” (see p. 98) so
Sex-linked traits are also possible – that their metabolisms produce necessary proteins. Once the human genome and
in the case of a variant race, this means several nonhuman genomes are mapped and sequenced, complex human transgengi-
that males and females will have neering could become a reality, limited mainly by ethical considerations.
slightly different racial templates. Adding traits from very different species – like insects, plants or aliens – proba-
bly requires high technology (TL11+), unless the genetic sequences are extremely
simple. The guidelines under Designing Variant Human Templates (p. 29) suggest
TLs at which various advantages and disadvantages can be produced by gengineer-
ing.
Chimerization
Technically, a chimera is an entity created when the cells of two dissimilar blas-
tocysts (very early embryos) are carefully fused together so that they form a single
organism. If the blastocysts are from different species, the result – if it survives –
will be a new creature with traits of both.
While a “classic” chimera is not too difficult to achieve with bacteria, plants or
very closely related animals (e.g., between dog and wolf blastocysts), the likelihood of
a viable chimera declines as the species become more diverse. To produce more exotic
chimeras, such as human/wolf, the germ cells from each embryo must undergo genetic
engineering to improve their compatibility. Additional cell grafts or microsurgery are
used to ensure the correct mix of cells and to correct any resulting deformities in the
Objectives of Human Gengineering elite would not only think they were
superior, but would actually be so,
genetically speaking. This could turn
Once we have the technology to radically redesign a human, would we want to
the gulf between rich and poor into a
do it? Here are some reasons that might drive gengineers: gaping chasm, or lead to a backlash if
Strength
ST may be enhanced by eugenic modifications to ensure a hefty build.
Alterations to the endocrine system may promote growth of muscle over fat. The
structure of both voluntary and involuntary muscle tissue can be modified with
Why Make more or stronger fibers. Species modification may actually improve the bones them-
Ubermenschen? selves, increasing their structural strength and allowing stronger attachment points
for muscles. At high TLs, alterations to the mitochondria (see Eve, Eukaryotes and
Genetic engineering to allow super- Organelles, p. 8) might improve the way the body uses its own energy resources.
human physical feats is useful for many
physically-demanding jobs, but espe-
cially for covert operations, where bion-
Dexterity
ics or powered suits might be too easy DX may be improved by eugenic modification to ensure an athletic body type,
to detect. Modern military forces may or at high TLs, by modifying nerve fibers and the spinal cord for faster nerve
also find biological enhancement easier impulse transmission.
on logistical grounds – a gene-enhanced
soldier may not be quite as strong as a
robot or suit, but at least he doesn’t
Intelligence
require any special maintenance. IQ may be improved by subtle neurological changes (see Brain Modifications,
Since modifications to ST and DX p. 32) or by increasing brain surface area. These are delicate procedures, requiring
are purely physical, they would be sophisticated neuropsychological and genetic science, and are probably impossible
amenable to animal testing. Several before TL10. Species modification may actually increase the size of the brain.
models of enhanced “super-animals”
were probably designed before any
super-humans were. Even if the animals Health
weren’t put into production, a few pro- HT may be increased by a spectrum of genetic changes, ranging from eliminat-
totype super-critters might be found in ing genetic defects and hereditary tendencies toward degenerative illness to gengi-
(or escape from) labs. neering away the appendix. Species modification to produce high racial HT bonuses
Many species modifications (and to
a lesser extent, almost all genetic modi-
may physically alter internal anatomy, especially the cardiovascular, respiratory,
fications) produce effects that can be gastrointestinal and immune systems.
replicated more cheaply by technology.
Why bother to use feline genes to give
someone fur or claws when you can get
the same or better effect with a weather-
proof jacket and a knife?
First, parahumans may be designed
as frontier colonists or workers on
worlds with harsh environments. A bio-
logical edge may be useful if disaster
leads to a technological breakdown.
Even if it doesn’t, being able to survive
outdoors (even briefly) without artificial
aids brings a welcome sense of security,
contributing to the psychological health
of the community.
Continued on next page . . .
Gengineered Advantages
The following sections discuss changes that might plausibly be bioengineered
into a variant human race to produce various advantages (a few associated disad-
vantages are also included; see Gengineered Disadvantages, p. 51, for more).
Rather than repeat the racial generation rules in yet another GURPS supplement,
we’ve assumed familiarity with this system, as presented in GURPS Aliens, Blood
Types, Compendium I, Fantasy Folk and Uplift, and have instead included only
the point costs and names of advantages or disadvantages, plus page references to
GURPS Basic Set or Compendium I.
Gastrointestinal Modifications
Name Cost Page TL
Species Modification: __________________________________________________
No Appendix 0 – 9
Sanitized Metabolism 5 CI65 9
Cast Iron Stomach 15 CI51 10
Universal Digestion 15 CI69 11
Glandular Modifications
“Well, sir, we’ve been grown with the Gen-Five supergland. Whenever our
model goes into overdrive, we get these cravings afterward. No, sir, we didn’t mean
DX +1 (10 points), HT +1 (10 A network of internal glands, the endocrine system, secretes hundreds of different
points). hormones into the bloodstream. These hormones regulate the body’s growth, develop-
Racial Advantages: Attractive (5 ment and routine metabolic processes, as well as emergency, emotional and sexual
points), Disease-Resistant (5 points), responses. Selective glandular biomodification can optimize the body’s hormonal bal-
Longevity (5 points). ance so that a person will develop in a certain way (more muscular, for instance), per-
Racial Disadvantages: None. form differently under stress, or experience stronger or weaker passions.
Features: Taboo Traits (Genetic
Defects, Mental Instability).
Gengineering of the hypothalamus, pituitary and thyroid glands, or designing
Racial Cost: 35 points. new, voluntary regulatory glands that produce similar hormones, could adjust meta-
bolic processes such as growth and maturation, permit increased activity (at the cost
Careful eugenic improvements of greater food consumption), or possibly allow control over normally involuntary
ensure an attractive, athletic, healthy biological functions like respiration and digestion.
individual. Medscanning may reveal It may also be feasible to engineer for short-term “emergency performance” or
minor “mutations” compared to the to improve stress response in general. One goal would be to allow voluntary control
human norm, such as being born with-
out an appendix. This is a simple
of the sudden bursts of “hysterical” speed or strength that some people are capable
“Homo superior” genotype that TL9+ of in emergencies. This might require genetic tinkering to modify the adrenal glands
parents – or societies – might select for or, as with metabolic control, the creation of new voluntary glands that produce sim-
their children. ilar hormones. This would be represented by Hyper-Strength or Hyper-Reflexes, or
by advantages like Combat Reflexes and Increased Speed.
By tinkering with hormones, the gengineer can also adjust human behavior, cre-
ating a variant human whose emotions are somewhat skewed in a desired direction.
Modifications of this sort usually center on the adrenal gland, the gonads (which
control influential sex hormones such as estrogens – e.g., estradiol – and androgens
– e.g., testosterone) or the pituitary (which produces hormones that influence other
glands). The strongest influence will be on the three “primal” human responses:
fear, aggression and sexual behaviour.
Glandular Modifications
Name Cost Page TL
Metabolic: ____________________________________________________________
Early Maturation 5/level CI53 9*
Hyperactive 30 CI57 9
Improved G-Tolerance 5/10 CI26 9
Metabolism Control 5/level CI60 9*
for hibernation 2.5/level CI60 9*
Emergency-response: __________________________________________________
Combat Reflexes 15 B20 9
Hyper-Reflexes 15 CI58 9
Hyper-Strength 30 CI58 9
Increased Speed +1-2 25/50 CI26 9
Increased Speed +3 75 CI26 10
Behavioral: __________________________________________________________
Collected/Composed 5 CI22 9
Cool 1 CI23 9
Fearlessness +1-5 2/level CI25 9
Imperturbable 10 CI26 9
Unfazeable 15 CI31 9
Pheromone Modifications
I believe that we can gain further control over the next
generation by restoring the vestigial vomeronasal system,
which reacts to airborne pheromones. Unlike lower animals,
whose pheromone vulnerability is limited by mating seasons,
humans with this genemod may experience irregular, height-
ened states of arousal. More important for our purposes, they
will become far more vulnerable to enhanced pheromones,
such as those produced by the pheromone glands and
aerosols we have developed.
– Dr. Tse Chang, Report to the Genetic Planning
Council
Modifications to the liver are usually aimed at selectively improving its metabo-
lization and detoxification abilities, giving better resistance to the effects of blood
Morphological Changes
No terrestrial vertebrate strays from the fundamental skeletal pattern of a crani-
um, four limbs and a tail. In some animals, certain of these features are enhanced
and others are atrophied – sometimes to invisibility. For example, dolphins replace
their legs with flippers and a huge tail, snakes have no limbs, while humans have
only a vestigial tail bone, but differentiate their limbs into arms and legs.
Nevertheless, the basic pattern remains.
Genetic engineering can alter humans within these limits between TL9 and 10,
changing the function of limbs (or deleting them), adding a tail or altering body
posture. However, deviating from vertebrate morphology to give humans more than
four functional limbs, or other exotic changes, requires TL11+.
Modified Limbs
First time I saw the new foreman, I was a little skeptical: a work shack’s
cramped enough without two extra elbows. That lasted until I saw what Lyra could
do in zero-G – we got the new solar panels up in record time. A few days later, Lyra
invited me to her apartment, in the station hub where it’s always weightless. That
night, she showed me another reason to appreciate four hands.
– Copernicus Jones, Posthumans I’ve Known
Except for an extra pair of arms, all of the above modifications are mutually
incompatible.
Modified Limbs
Name Cost Page TL
Digitigrade Posture 0 – 9
Legs to Flippers 0 – 9
Prehensile Toes 7 – 9
Legs to Arms 3 – 10
Extra Arms 10/arm CI54 11
Gengineered Tails
“How’d I get away? Well, Galba’s assassin had the drop on me. I set my drink-
ing bulb down on the table behind me and raised my hands. He watched them care-
fully. He forgot I was a spacer. He wasn’t watching my tail.”
– Captain Zeke Morrigan, free trader Antares
Humans have a vestigial tailbone; species gengineering could use genes from
other species to give humans a tail. This might be done for cosmetic reasons, or the
tail may be usable as a weapon or a functional extra arm.
Heavy Worlder (TL9) Ordinary Tail (TL9): A normal animal tail, with various styles available (cat,
wolf, pony, rabbit, rat, et cetera). Clothing should be designed with tail flaps! A 0-
ST +3 (30 points), HT +1 (10
points).
point feature.
Racial Advantages: Improved G- Prehensile Tail (TL10): A tail capable of grasping, like a monkey’s. This is
Tolerance (0.5 G increment, 10 points) higher TL, as it requires modifications to the brain and nervous system as well. It
with home gravity (p. S36) of 1.5 to 2 may be a popular biomod feature for spacers, where an additional grasping limb is
G. always useful. Treat as an Extra Arm with no physical attack (p. CI54; 5 points).
Racial Disadvantages: Unattractive Scorpion Tail (TL12): A segmented tail with a barbed, poisoned tip. Treat as a
(-5 points). Striker, reach 1, -4 DX, thrust+1 impaling damage (26 points), with Venom, 3 levels
Racial Cost: 45 points.
(Limited Use, 4/day -20%, 36 points).
A heavy worlder’s weight is 25%
over the human norm, but height is 1’
less than indicated for ST. Someone
Gengineered Tails
Name Cost Page TL
with this modification is wider, which Ordinary Tail 0 – 9
can give problems in narrow passages
or doors designed for normal humans (a
Prehensile Tail 5 – 10
DX roll to squeeze through). Scorpion Tail 62 – 12
This is a variant human designed for
life in a 1.5 to 2 G environment. He has
more muscle to get around, stronger
bones to avoid breaking them in falls,
Winged Humans
“We can synthesize the DNA for feathered or bat-like wings, but you can’t just
and a redesigned circulatory system to
prevent early death due to heart failure. splice wings into a normal genotype and expect it to fly. Thanks to the square-cube
Modifications for high gravity are simi- law, a set big enough to lift even a child isn’t practical. Sure, you can expand the
lar to those used for superhuman wingspan, but then you end up with wings 50 or 60 feet across. Aside from the
strength (p. 30), with greater emphasis inconvenience, you’ll run into problems of structural strength and finding the mus-
placed on redesigning the heart and cir- cles needed to flap them.
culatory system for durability. “As a result, winged bioroids typically have wingspans of about twice their height.
However, the “heavy-worlder” is usu- While this can be a visually attractive feature, they have no chance on Earth of flying. I
ally unattractive by human standards,
with a barrel chest and a compact, use that cliche deliberately: if you can find an extra-terrestrial environment with a
blocky body. lower gravity but normal or higher atmospheric pressure, then you’re in luck. Planets
like that are rare, but there are artificial habitats. Our Camazotz-series bioroids were
Devolutionary Modifications
Some morphological modifications take a backward step down the
evolutionary path, causing humans to revert to more bestial forms. These
are most likely intended for the creation of toys or slave races, although a
very advanced civilization might enjoy creating blank-minded clone bod-
ies this way, then “uploading” their minds into them as a new experience.
Musculo-Skeletal Modifications
The BS-2-F Felicia-series combat bioroid is a “special
forces” upgrade of our popular AS-2-E, with a wide-spectrum
of state-of-the-art improvements. In this vidclip, we see a fire
team of BS-2-Fs free-jumping from a helicopter 12 meters up
and landing on their feet without injury, thanks to their XM-723
feline morphology.
– Biotech Euphrates promo video at WarEx ’47 trade show
“Meow.”
– Felicia-series bioroid, upon landing on enemy soldier
Respiratory Alternatives
Ever looked at an embryo? It’s got gills. Gengineering to retain these vestigial
traits should be relatively simple, right?
– Aquagrrl, sci.bio.genemod.human
It’s true that human embryos have gill-like structures – but these serve a differ-
ent function than in fish or amphibians, eventually forming the chin, jaw, cheek and
outer ear. As a result, gengineering a merman is a lot more difficult than Aquagrrl
implies, especially if we want to breathe both air and water. So far, most dual-
environment humans are designed like marine mammals. Navy SEAL bioroids don’t
use gills. They store oxygen in the myoglobin of the muscles, just like whales do.
When drawing oxygen from these sources, their lungs aren’t necessary, so they can
undergo complete alveolar collapse as water pressure increases, letting them ignore
the bends and survive very deep dives.
– DocIqbal, sci.bio.genemod.human
Respiratory Alternatives
Name Cost Page TL
Gills:
water only 0 CI56 9
air and water 10 CI56 10
Oxygen Storage 14 CI62 9
Pressure Support:
to 10 atmospheres 5 CI63 10*
to 100 atmospheres 10 CI63 11*
immune to pressure 15 CI63 12*
Sensory Modifications
Name Cost Page TL
Spacer Acute Hearing +1-5
Acute Vision +1-5
2/level
2/level
B19
B19
8
8
Modification Absolute Direction 5 B19 9
(TL9) Absolute Timing
Acute Taste and Smell +1-5
5
2/level
B19
B19
9
9
Peripheral Vision 15 B22 9
ST -5 (-40 points), HT -2 (-15 Species Modification: __________________________________________________
points). Acute Hearing 6+ 2/level B19 9
Racial Advantages: Free Fall +3 (4 Acute Vision 6+ 2/level B19 9
points), Slow Regeneration (only to
Discriminatory Smell 15 CI52 9
replace bone decalcification, -75%, 3
points). Discriminatory Taste 10 CI53 9
Racial Disadvantages: G-Intolerance Faz Sense 10 CI55 9
(0.05G increment, -20 points), Skinny Night Vision 10 B22 9
(-5 points). Perfect Balance 15 CI63 9
Features: Home gravity (p. S36) of Subsonic Hearing 0/5* CI67 9
0 G. Increase height by up to 3 feet Ultrahearing 0/5* CI69 9
over the norm for the lowered ST, but
Acute Taste and Smell 6+ 2/level B19 10
weight is 25% to 50% of normal.
Racial Cost: -73 points. Infravision 15 CI58 10
Sensitive Touch 10 CI65 10
In micro- or zero gravity, the lack of Sonar Vision 0/25 CI66 10
weight seems to affect development, Telescopic Vision 6/level CI68 10
causing brittle bones. Gengineering may Field Sense 10 CI55 11
be aimed at modifying the parathyroid Magnetic Sense 5/level CI60 11
gland to restore calcium levels, and oth- Parabolic Hearing 4/level CI62 11
erwise adjusting the metabolism to life Polarized Eyes 5 CI63 11
in zero-G. Individuals modified for
micro- or zero gravity tend to be very
tall and emaciated – some “spacers” * Ultrahearing and Subsonic Hearing cost 0 points if the possessor is deaf to the
may be unattractive, while others have normal hearing range.
an elfin beauty.
Limitations: Eye Contact Only (-20%; see p. CI110) can be applied to sensory
advantages, even if they don’t actually require eye contact, to limit their range to 3
yards. Faz Sense, Infravision and Sonar Vision can all be limited in this way to rep-
46 HUMAN GENETIC ENGINEERING
resent shorter-ranged (and, in humans, more feasible) forms of these advantages. If
so, reduce the required TL by one.
Side Effects: Any species modifications (except Acute Vision, Night Vision,
Camazotz-Series
Perfect Balance or Telescopic Vision) are likely to produce disorientation or sensory
overload. This may result in one or more of these disadvantages: Confused, Light
Parahuman (TL10)
Sleeper or Migraines. The brain might be able to develop structures to mitigate such
ST -2 (-15 points), DX +1 (10
problems, although this may also cause a slight drop in IQ or loss of other senses.
points).
Racial Advantages: Acute Hearing
Revised Pain Thresholds +2 (4 points), Acute Taste and Smell +1
(2 points), Claws (15 points), Flight
I knew I was going to join the ranks of the ethically-challenged when the
(Winged, -25%; Requires Low Gravity:
Sultana offered me twenty grand to create a clone of her ex-husband with a gengi- 0.3 G, -35%; Nuisance Effect: No Fine
neered low pain threshold. Manipulators, -30%; 10 points), Fur (4
– Dr. Lucien Locke, Genehackers Inc. points), Sharp Teeth (5 points), Sonar
Vision (25 points), 3D Spatial Sense (10
Pain sensitivity is vital. People born without it die early – by accident, or from points), Ultrahearing (5 points).
infection resulting from internal joint and bone damage. (They are unable to tell Racial Disadvantages: Fragile (-20
when a particular posture or sleeping position is over-stressing joints or bones, and points), Skinny (-5 points), Unusual
Biochemistry (-5 points).
so do not receive signals to shift weight or otherwise take corrective measures while Features: Due to their hollow bones
sleeping or awake.) However, while total insensitivity to pain is not a survival char- and slight build, weight is 50% of the
acteristic, the ability to selectively block pain is quite useful. norm for their height.
Through genetic modification of the genes responsible for “signal molecules” Racial Cost: 45 points.
that induce changes in nerve cells, or via transplants of gengineered nerve tissue to
the notochord (the embryonic spine), it may be possible to activate neural gating Camazotz-series parahumans have a
circuits in the spinal cord to deliberately mitigate incoming pain signals before they sizable percentage of bat genes spliced
are perceived, without destroying the ability to sense pain as a whole. Of course, the into their genome. Their arms double as
opposite could be done to enhance the ability to feel pain . . . wings, although they can’t be used as
arms when they’re flying. They possess
Altered Sex Ratio modifies the ratio of male to female births. This can be a spe-
cific ratio (e.g., five women to every man) or even eliminate births of either sex.
This is a 0-point feature.
Transformations
Today, Kosmozavot Tenno Tanjo’s gengineers announced success on their Void-
Dancer project. They’ve added a vacuum-adaptive skin, special muscle sphincters
that seal guts and lungs, and nictating membranes for the eyes. The Void-Dancer
parahumans are supposed to survive in space without protective gear for an hour or
more. According to KTT, the productivity and cost savings from being able to avoid
suit-up/suit-down time, safety checks and suit training alone will pay for the program.
– Chance Mackintosh, Posthuman Consumer Review
At very high TLs, highly unusual changes are possible, probably using com-
pletely synthetic DNA sequences. Elastic Skin or Vacuum Adaptation, for instance,
require the creation of new voluntary muscles (to change shape in one case, to close
off openings in the other) and the extensive bioengineering of skin cells and, in the
case of Vacuum Adaptation, internal organs.
This kind of modification may be more realistically achieved with exotic nan-
otech than gengineering, in conjunction with numerous limitations – for examples,
see Sample Metamorphosis Transformations (p. 81) in Chapter 3.
Transformations
Name Cost Page TL
Elastic Skin 20 CI53 11
Vacuum Adaptation 27 CI69 11
Doesn’t Breathe 20 CI53 12
Doesn’t Eat or Drink 10 CI53 12
Flexibility 15 CI56 12
Morph 40 CI61 13
Vacuum Support 40 CI70 13
Xeno-Anatomy
These are traits that humans don’t possess at all, such as claws or fur. They are
borrowed from terrestrial animals by direct transgenic gene splicing, or more com-
monly, by creating synthetic genes copied from or patterned on other species:
Amphibious represents gengineering for webbed fingers and toes, and is often
associated with a sleek coat of fur like a seal, or very light scales.
Bioelectric Organ is an exotic modification that uses modified plates
formed from muscle tissue, derived from electric eel genes. This may give
Bioelectric Shock (p. CI50), Shock or Surge (p. CI73). The latter two should have
Xeno-Anatomy
Name Cost Page TL
Amphibious 10 CI49 9
Flesh Pockets varies 136 9
Temperature Tolerance 1-9 1/level CI30 9
Nictating Membrane 10/level CI62 10
Temperature Tolerance 10+ 1/level CI30 *
Clinging 25 CI51 11**
Xeno-Skin: ____________________________________________________________
Fur:
very thin 0 CI56 9
regular 4 CI56 9
thick 29 CI56 9
spiny 33 CI56 10
Scales
very light 0 CI57 10
regular 3 CI57 11
heavy 28 CI57 11
Thick Hide 28 CI57 10
Armor Plates 59 CI57 11
Carapace 56 CI57 12
Chameleon 7/level CI51 12
Gilgamesh-Series Strikers: ______________________________________________________________
Physical Disadvantages
Intended Defects: Some variant races are eugeneered with deliberate physical
defects. For example, a wealthy sadist might want his latest concubine to be an albi-
no with Low Pain Threshold, while the eccentric Sultana of Gideon Prime might
desire her bodyguard of gene-enhanced janissaries to have both Gigantism and
Mute. The most commonly engineered physical disadvantages chosen for aesthetic
effect are Albinism, Dwarfism, Eunuch, Fat, Gigantism, Light Sleeper, Low Pain
Threshold, Mute, Overweight, Skinny and Sterile.
Self-Destruct and Short Lifespan are also common in slave races, produced
through modifications to the endocrine system or built in “suicide clocks” in cells.
Usually, the goal is to ensure demand for new product via planned obsolescence.
Short Lifespan might also be popular for non-sterile slave races, as it allows faster
reproduction; in bioengineered humans that aren’t property, the advantage Early
Maturation would be used instead.
Unintended Defects: IQ or HT penalties, Delicate Metabolism, Low Pain
Threshold, Sterile, Unusual Biochemistry and Weak Immune System are the most
Physical Disadvantages
Disadvantage Cost Page
Albinism -10 B27
Appearance varies B15
Bad Sight -10/-25 B27
Color Blindness -10 B28
Deafness -20 B28
Delicate Metabolism -20/-40 CI81
Disturbing Voice -10 CI81
Dwarfism -15 B28
Epilepsy -30 B28
Eunuch -5 B28
Extra Sleep -3/level CI81
Fat -10/20 B28
Gigantism -10 B28
Gluttony -5 B33
Hard of Hearing -10 B28
Light Sleeper -5 CI82
Low Pain Threshold -10 B29
Migraine -5 to -20 CI82
Mute -25 B29
Overweight -5 B29
Reduced Hit Points -5/level CI83
Skinny -5 B29
Sterile -3 CI84
Unnatural Feature* -5 CI85
Weak Immune System -30 CI85
Species Modification
Aquatic -40 CI101
Fragile -20 CI102
Reduced Move -5/point CI103
Self-Destruct -20 CI104
Short Lifespan -10/level CI104
Sleepy varies CI104
Slow Healing -5/level CI104
Unusual Biochemistry -5 CI106
* Remember, this only qualifies if the feature is somewhat disturbing and the
variant race is otherwise human-like.
Other Features
Besides specific modifications or defects, a race may also have a variety of sec-
Sense (10 points).
Racial Disadvantages: Gluttony (-5
points), Reduced Hit Points -5 (-25
points).
ondary, 0-point features. Several such features appear under Gengineered Features: Miniature (2/5-scale).
Advantages (p. 51ff). One special class of features, taboo traits, merits additional After calculating height and weight
discussion. based on ST, multiply height by 2/5 and
weight by 1/16. Normally has 6 meals a
day, but each is only 1/16 as large as a
Taboo Traits human meal.
Racial Cost: -30 points.
Some genetic constructs undergo selection to screen out or mitigate undesirable
traits; therefore, certain advantages or disadvantages may be forbidden to individual Fourth Officer Ratzelle is just over
characters built with such racial templates. A forbidden advantage or disadvantage two feet tall, has short brown fur, and
is called a taboo trait (p. CI176). It costs no character points to assign a taboo trait lives in the vacc-suit locker. Her cover-
to a racial template – it’s a 0-point feature. all is always covered in grease, her
For instance, a character can normally have Berserk as a personal disadvantage, voice is an irritating chitter, and when
she’s not working, she’s stuffing her
even if it isn’t in his genetic template. However, if Berserk is a taboo trait for his face with junk food. But who’s com-
template, then it cannot be taken. plaining? Hiring her was the first smart
Taboo traits that cover a general class of disadvantages do not prevent specific move the captain pulled since he
disadvantages from within that class from being part of the racial template. The pro- spaced the S-3 unit. Now our hyper-
hibition is also lifted for disadvantages that are acquired after birth (e.g., due to a drive works all the time, the nanotoast-
proteus virus or brainwashing). er’s no longer a menace and she even
One way to add a taboo trait to a template is through genefixing. squirmed up the Milliken Tube to hose
the scorpio wasps out of number-two
Custom Designs
If no one has designed a particular trait before, the germline gengineering pro-
cedures (Chapter 1, p. 9) should be used. People can hire a genetic engineer (see the
Job Table, p. 133) or do the job themselves.
First, human gametes (egg and sperm cells) are needed. These might be provid-
ed by the customer (one or two parents might donate their own reproductive cells
for modification), or be specially selected for their eugenic characteristics.
Second, a gengineer with an appropriately-equipped lab is required. Custom
gengineering requires a genetics lab. Hiring a genetic engineer (or a biotech compa-
ny) to add new modifications to a particular human zygote is expensive.
The resulting racial template may vary somewhat from the designer’s intentions
– in game terms, the person ordering the gengineering specifies the desired changes,
then the GM adds additional “unintended” disadvantages based on how well or
poorly the gengineering was performed. Any trait not specifically gengineered (that
is, specified in a racial template) will depend on the genetic parents (whoever pro-
vided the egg cell and sperm used).
If the concept roll was a critical failure, all working models will be non-viable
or worse! NPCs will usually realize their concept is flawed after 1d failed attempts
(twice as many if they have Stubbornness); players may keep trying until repeated
failures suggest to them that something is wrong.
BIOMODS 61
Operation: To decrease Appearance by any Statistics: Sex Appeal +3 (3 points) plus
number of levels, or to change features so that an Unnatural Feature (exaggerated sexual features,
acquaintance needs an IQ roll to recognize you, -5 points). -2 points.
costs $500 (and takes one week to recover from). Operation: $5,000 (and one week). It is usu-
To increase Appearance by one level costs ally preceded or followed by surgery to increase
$1,000 (and takes 2 weeks). Two levels cost Appearance. LC 5.
$5,000 (and 3 weeks), and the same degree of
surgery can alter appearance to make someone
unrecognizable, or give him a recognizable but
Hair Graft (TL7/8)
inexact copy of another’s face (“You look sort of At TL8+, living hair or fur strips may be
like Elvis.”). However, if a person naturally looks grafted onto certain parts of the body, such as the
like another person (excluding hair and eyes), he spine, ankles or wrists, for an exotic look. Of
may be modified to look exactly like his near- course, it’s also possible to cure baldness this
double for the price and time quoted above. way; this is TL7 rather than TL8, and is half as
At TL8+ only, to increase Appearance by expensive.
three levels takes $25,000 (and 3 weeks). The same Statistics: Usually a 0-point feature, but may
effort can also turn someone into an exact duplicate qualify as an Unnatural Feature.
of another person (as much as height and build per- Operation: $1,000 (and one day). LC 6.
mit), including that person’s level of Appearance.
Removing a person’s finger-, palm- or footprints
(TL7) takes $2,000 and 2 weeks; changing them
Sex Cha nge (TL7/8)
It’s fashionable for hetero parents to swap
(TL8) costs 10 times as much.
sexes after each child, so they can both have a try
All changes are LC 6 (except changing prints, which is LC
at being pregnant. This is perfectly healthy, but do be cautioned
3). However, making exact copies of a famous person may be a
that some people seem to be predominantly male or female, and
copyright or trademark violation!
won’t be comfortable in the other gender for the months that a
Altered Bulk (TL7/8) natural childbirth requires. See your psychogenetic counselor
first!
“When I told the doc I wanted to gain weight, he was – Dr. Lucien Locke, Sexmorphing and You
shocked. I told him it was for a movie – well, I wasn’t going to
admit I needed some extra room to hide my flesh holster, was I?” The procedures and effects depend on the level of sex
– Detective Cody Chase, Nevada PD change:
Superficial (TL7/8): The subject retains his/her own sex,
Fatty tissue can be removed surgically through techniques but when fully dressed appears to be a member of the opposite
such as liposuction, or it can be grafted onto the body. sex.
Statistics: Bulk can be safely altered up or down by one Full Cosmetic (TL7/8): The subject completely resembles
step. The steps range from a maximum of Very Fat (-20 points), his/her new sex. Only a medical examination would reveal that
to Fat (-10 points), Overweight (-5 points) and normal weight, a sex change had taken place. To all exterior appearances and
down to a minimum of Skinny (-5 points), in that order. After for all social interactions, the change is total, except reproduc-
the operation, adjust weight accordingly. tion is impossible.
Operation: $5,000 (and one week). LC 6. Complete (TL8): This is a total sex change, with full capac-
ity for reproduction being possible. This requires growing a
Extreme Sexual Dimorphism (TL7/8) cross-sex clone (p. 16) and transplanting organs from it into the
Would you like to make onlookers pant with lust or moan recipient’s body, although at TL12+, proteus nanoviruses can
with envy? Come to Novabody, where we can turn you or your design working reproductive organs and cells within the
partner into the stuff of fantasy. Our fast, safe biosculpt proce- patient’s own body.
dures exaggerate primary male and secondary female sexual
attributes, with striking results achieved in hours! Statistics: If full cosmetic, the subject is Sterile (-3 points).
– Novabody: Nirvana is Now A functional sex change can sometimes alter personality, as a
result of the hormones used and the change in self-image. At the
“Yes, you too can be stacked like a pleasure bioroid. No GM’s option, a sex change can justify buying off or exchanging
thanks. I’ve heard rumors that the majority of Novabody’s a few mental disadvantages.
clients work for, quote, escort services, unquote, and that some Operation: A superficial sex change is $8,000 (and 2
of the surgery is a little less than elective, if you take my mean- weeks). A full cosmetic sex change is $30,000 (and 4 weeks). A
ing. Custom cuties, anyone?” complete sex change is $30,000 (and 8 weeks) for a male-to-
– Detective Cody Chase, Nevada PD female change, or $100,000 (and 10 weeks) for a female-to-
62 BIOMODS
male, the latter requiring the creation of an artificial Y chromo- Statistics: Any of Catfall (10 points), Double-Jointed (5
some, which is trickier. Sex changes are LC 5. points) or Manual Dexterity +1 (3 points).
Operation: $20,000 (and 2 weeks) per advantage. LC 5.
Altered Height (TL8) Muscle Graft (TL8)
Height can be altered surgically by up to 3” in either direc-
tion through adjustments to the long bones of the arms and legs. Tired of getting sand kicked in your face? Want the body
Slight modifications to the spine can add an extra 3”. your lover has always dreamed off? Try SpaTek’s muscle graft-
Statistics: No point cost unless the modification results in ing! Bulk up in record time while avoiding the metabolic haz-
Dwarfism or Gigantism (or adjusts height surgically so that the ards of conventional muscle-enhancing drugs and the risks of
character no longer qualifies for such a disadvantage). transplant rejection. Strong, safe and swift: It’s SpaTek.
Operation $8,000/inch (and one week, or three if spinal). – SpaTek advertisement
LC 6.
Way I see it, muscle grafting is kind of the surgical version
Archwork (TL8) of steroid pushing – a quick and dirty way to bulk up real fast, if
you don’t have the self-discipline or the time for body building
“This bold fashionmod from the spring collection of Milan or the valuta for something more subtle. Graft’s the sort of thing
bodysculptor Fox Delamere coaxes you into a ballerina’s deli- you’d see on MafInc muscleboys or some simstar’s bodyguards.
cate, toe-first walk with modifications to the tendons and arch- Kind of low class. Por favor, chum: Don’t tell “Mountain”
es in the feet! Thanks to supplementary bone reinforcement, Mahoney I said that, or he’ll break my spine.
you’ll be fully comfortable – and if you wear high heels, this – Streethawk, alt.bio.upgrade.samurai.livechat
makes a day spent walking in them as ache-free as if you’d
worn flats.” Statistics: Select from +1 to +3 ST. Pay for it like any
– Noriko Hayakawa, host of Cyberia Beat. improvement in ST, except that the doubled cost for increasing
ST after initial character creation does not apply. Then buy the
“Sure it’s striking on a supermodel like same number of levels of Reduced Fatigue (-3
Alicia Lordes, but didn’t this silliness die out in points/level), reducing the cost of the strength
pre-space China? Still, at least Delamere set it up increase. This reflects the fact that this ST only
so it isn’t physical torture any more.” applies to limb muscles, not to internal muscles
– Chance Mackintosh, Posthuman Consumer like heart or lungs. Boosting ST by muscle grafts
Review. adds 10 pounds to weight per point of ST increase.
Optionally, characters who gained +3 ST from
Statistics: Adds 2” to height when barefoot, muscle grafts can take the Unsupported Strength
and you can wear high heels or dance shoes indef- limitation (p. 138).
initely without pain; regular footwear is uncom- Operation: $20,000 (and 4 weeks). If using a
fortable (0 points). muscle-boosting nanovirus, half the ST gain
Operation: $5,000 (and 2 weeks). You can be (round down) occurs after two weeks, with the
up and around after surgery, but treat as Lame remainder at the end of the growth period. LC 6.
while recovering. LC 6.
BIOMODS 63
Operation: $4,000 (and 2 weeks). Treat as and muscle that can be wagged is a transplant;
Eunuch while recovering from surgery, but no see Tail Grafts (p. 66).
bed rest is required. LC 6. Cheap version is Xenosculpting is LC 6.
$1,000 (and 1 week). LC 6.
64 BIOMODS
Transplants Rejection and Immunosuppression
Need a new or better body part? Why not just graft one on? Rejection is a risk when using transplants that are neither
Transplants aren’t new technology. The first successful from a donor who’s the clone or identical twin of the recipient
organ transplant occurred in 1954, when a man with failing kid- nor vat-grown. The danger can be reduced by using genetic tests
neys received a transplant from his twin brother. (Kidneys come to find donor tissue that more closely matches the recipient
in pairs, so it’s possible to give one up for a transplant and still (mid-TL7); if genetically-matched tissue is unavailable, then the
survive.) A twin was needed because of the major difficulty of recipient should only accept tissue from a donor of the same
transplant operations: tissue rejection. blood type. Use of donated tissue is usually combined with a
Rejection occurs when the body’s proteins work together cocktail of drugs used to suppress the patient’s immune system
with antibodies to destroy foreign tissue, treating it as an invad- long enough for the transplant to become part of the body.
ing organism. The result is an inflammatory response, infection Check for tissue rejection mid-way through the recovery period.
and possible death if the transplant is not removed. The best Rejection is automatic if the donor and recipient have dif-
way to fool the immune system is to have tissue that is geneti- ferent blood types. Otherwise, a HT roll must be failed to avoid
cally identical. In nature, this means tissue from a twin. rejection. Modify the patient’s HT (for this roll only) as follows:
Since few people have identical twins willing to donate +5 if no tissue matching was performed; +2 if a xenotransplant
their organs, tissue from non-genetically-identical sources is (p. 66). If the recipient has Panimmunity or is Disease-Resistant,
usually used instead, and immune response is suppressed with his bonuses to resist disease add to HT; if he has Immunity to
drugs. In the future (late TL8+), “blank mind” clones may be Disease (or level 3 Panimmunity), add +10. A regimen of
grown and used as donors – see Clones as Spare Parts (p. 17). immunosuppressant drugs (available from late TL7 on) gives
A more practical alternative is to grow individual body the patient -TL to HT on the roll for tissue rejection and halves
parts – see Vat-Grown Organs and Parts (p. 17). These may (round down) bonuses for Panimmunity, Disease-Resistant or
also be genetically altered, so that modified body parts can be Immunity to Disease. However, this also leaves the patient vul-
grown and harvested. Such “biomod transplants” may serve nerable to new or existing infections – he gains the Weak
as the organic equivalent of cyberwear. It may also prove pos- Immune System disadvantage (p. CI85) for half again the dura-
sible to modify animals (such as pigs) to grow tissue – see tion of the recovery period after the transplant, which may
Chapter 4. require rolls to avoid catching a disease.
Effects of Rejection: Success on this HT roll means that
rejection starts about halfway into the recovery period. The
The Transplant Procedure patient must make a HT roll (HT-2 if a vital organ is being
rejected) every day, or lose 1 hit (1d hits on a critical failure).
Before a biomod transplant can get underway, the surgeon
Don’t apply any of the modifiers listed above to HT. The risk of
must have the limb or organ that is to be transplanted. Each
rejection damage continues until the implant or transplant is
organ or limb transplant has a listed “time to grow” in weeks.
removed or he dies. Removal requires an operation identical to
This assumes the biomod is custom-grown in a forced-growth
the original, but is easier (add +2 to skill). If a vital organ is
tank (p. 19) using samples from the subject’s cells. If forced-
removed, the patient must be placed on life support until an
growth technology does not exist, read “weeks” as “months.”
organic or bionic replacement can be found.
There may be faster ways to get a biomod body part. Some
companies resell “used” (salvaged or repossessed) body parts,
often on the black market. These can be purchased with no wait-
ing period, but as they are not tissue-matched, there’s a danger
Medical Transplants (TL7/8)
of rejection – see below. These are transplants of ordinary, unmodified organs, per-
The prices given for the transplant procedures in this chap- formed for therapeutic reasons: to replace organs that are degen-
ter include the cost of growing or otherwise purchasing the body erating or non-functional due to old age, disease or injury.
part as well as the operation itself, with one-third of the cost
being the cost of growing the part and the remaining two-thirds Therapeutic? Sure. But you can also use an eye transplant
representing the cost of the operation. Most transplant providers to change your retina print. Even saw one guy who grafted on a
require advance payment before they will begin growing a new hand so he could get past a palm-print scanner.
transplant. – Streethawk, alt.bio.samurai.upgrade.
Once it’s ready, the biomod can be attached immedi-
ately. Use the rules under Surgery Skill Rolls (p. 61). The
patient must rest and recuperate afterward, and each pro-
cedure has a listed recovery time. If the transplant came
from a non-identical donor (i.e., not a clone, twin or vat),
then there will be a risk of tissue rejection – see Rejection
and Immunosuppression (below) for the dangers and
effects.
A biomod organ or limb can be stored until it’s con-
venient, with the operation being performed and paid for
at a later date. Similarly, if a group of cyberpunks were to
salvage an organ from a body, they’d pay two-thirds as
much. If they performed the operation themselves, they’d
pay only one-third cost. If they did both, the process
would be free.
BIOMODS 65
Statistics: Replaces a body
part. At the GM’s discretion, Medical Xenotransplants (TL7/8)
replacing 1-3 major organs can These were begun experimentally at late TL7 (circa 1992)
possibly cure or arrest some dis- and become reliable by TL8. The goal is to replace a dying
eases or terminal illnesses, or human organ, such as an infected liver, with that of an animal
restore some or all ST or HT lost anatomically and genetically close to humanity, such as a
to aging, disease or radiation. baboon.
Operation: If vat-grown, 6 Medical xenotransplants are used for two reasons: First,
weeks to grow. Sample costs and they serve as a substitute for human organs that may be in short
recovery times for transplants: supply. Second, if the patient’s organs are failing due to an
$3,000 (and 2 weeks) for a minor infectious disease, the disease is less likely to “cross species”
part like an ear or finger, $7,500 and reinfect the new organ than it would were cloned or foreign
(and 4 weeks) for a liver, kidney human tissue used. In such cases, a xenotransplant may not only
or genitals; $15,000 (and 8 weeks) repair damage but also cure the disease (this should require a
for an arm, eye, foot, hand, heart, HT roll, at a penalty depending on the disease).
leg or lung. LC 6. Medical xenotransplants can be used to replace damaged or
If vat-grown organs are failing organs at 75% of the price of an ordinary therapeutic
unavailable (or the patient doesn’t organ transplant and with no waiting period. Careful screening
want to wait for them to grow), of the animal donor is performed to ensure it is healthy.
donated organs may be used.
They have the same prices, but
there will be a chance of tissue Cat’s Eye Transplant (TL8)
rejection (p. 65). Such organs may It’s cheaper and snazzier than a cybernetic eye, although it
be in short supply, with a black does look a bit obvious, especially in dim light when it glitters.
market that provides them to the ’Course, it can’t be upgraded.
rich or desperate. See The Organ – Streethawk, alt.bio.upgrade.samurai
Trade (p. 129) for possibilities.
For another option, see Medical Statistics: Night Vision (10 points). A set of feline eye
Xenotransplants (below). transplants may count as an Unnatural Feature (-5 points). There
is a -2 to Vision rolls unless both eyes are modified.
Brain Transplant (TL8) Operation: $5,000 per eye (6 weeks to grow, 8 weeks to
recover). Only a week of bed rest is needed, but the user will
At late TL8, it becomes possible to transplant a person’s be blind in the transplanted eye until the full time has elapsed.
entire brain and much of their spinal cord into a whole new LC 5.
body. Since brain cells don’t regenerate, this isn’t actual immor-
tality, but it can extend the lifespan.
Statistics: The GM should “set the clock back” on any
physical attributes (not IQ) lost to age, restoring them to the
Xenostriker Grafts (TL8)
My kid sister runs with the Unicorns, a gang of biopunks
level appropriate for that person at his new age. Optionally, the and genehackers down at the Cloisters. Vicious in a rumble, but
GM may charge him the character points for the improvement, real twisted – who else would be crazy enough to clone up nar-
just as though improved stats were being bought normally. If whal fetuses and transplant the horn buds into their foreheads?
brain transplants are likely, the GM may want to keep separate – Streethawk, alt.bio.upgrade.samurai.
track of the brain’s age (which will control the frequency of
rolls for IQ loss due to aging) and the body’s age (which con- Statistics Select any striker from the Xeno-Anatomy table
trols aging losses of ST, DX and HT). (p. 50). Claws, sharp claws, talons and sharp teeth are
Operation: $50,000 (and 8 weeks to recover). There is no retractable or concealable. The others are obvious, and also
need to grow an organ, since an existing brain is used. If trans- count as -5-point Unnatural Features if exotic biomods are
planting a brain into a person other than the original host, treat it uncommon. Before the operation, the claws, talons, horn buds
as a braintape transfer to a different body for its effect (see or tooth buds must be acquired.
Braintaping, p. 116). Brain transplants are LC 6. Operation: Costs $5,000 × (TL-7), where “TL” is the mini-
mum TL required for gengineering the same advantage. 6 weeks
Xenotransplants (TL7/8) to grow, 3 weeks to recover. LC 5.
66 BIOMODS
Statistics: Any of the tail types described under Operation: $2,000 per character point it costs, with a mini-
Gengineered Tails (p. 40) can be vat-grown and then transplant- mum of $5,000 (6 weeks to grow, 2 weeks recovery). LC 6.
ed. If biomods of this sort are unusual, a tail may be also qualify
as an Unnatural Feature (-5 points).
Operation: This costs $25,000 × (TL-8), where “TL” is the Auxiliary Heart (TL9)
minimum TL required for gengineering that type of tail. Thus, a “She’s not dead, damn it! Feel that slow heartbeat on the
prehensile tail (TL10) would cost $50,000. All tails take 3 right side of her chest? Her auxiliary heart just kicked in. It’s
weeks to grow before the transplant. Recovery time is 4 weeks smaller than her main heart, but it should keep the blood flow-
for prehensile or scorpion tails, 2 weeks for ordinary tails. Tails ing to her brain and lungs until we can medevac her.”
are LC 5, except for scorpion tails which are LC 3. – Lt. Dana Martello, Marine Force Recon, mission data log
upload
Tentacle Transplant (TL12) Statistics: Extra Hit Points +2 (10 points) and Hard to Kill
Okay, it’s a gene-altered transplant. What I want to know
+3 (15 points). 25 points.
is, what kind of thing they transplanted it from? I mean, does
Operation: $75,000 (6 weeks to grow, 8 weeks recovery).
that black clinic have a basement with some sort of stunted
LC 6.
octopoid/human hybrid floating in a growth tank?
– Streethawk, alt.bio.upgrade.samurai
Eye Upgrade (TL8) “I had a friend who got a Cheetah. Worked fine until he got
into a drawn-out fire fight in Kabul. Then his heart exploded.
If your eye offends thee, pluck it out and get a better one. Guess he should have gone easy on that cholesterol.”
Biomod ears or noses aren’t something you can really graft on – Captain (ret.) Dana Martello, Marine Force Recon
and hope for anything other than a cosmetic change, due to a
lot of the processing being wetware – i.e., in the brain – but Statistics: Hyper-Reflexes and Hyper-Strength, both with
since we’re better wired to handle enhanced visual input, and Cardiac Stress, -40% (see p. 137). 27 points.
most of an eye’s modifications are in the rod and cone cells, Operation: $27,000 (4 weeks to grow, 2 weeks recovery).
they’re fairly easy to improve though transplants. Mind you, you LC 5.
can’t get something exotic like infravision unless you want to
mess with nanoviruses and stuff – cyber’s much easier there.
– Streethawk, alt.bio.samurai.upgrade Boosted Heart (TL9)
Why stick with what nature gave you? VeldtKorp’s
Statistics: Cures Blindness (for 50 points), or Bad Sight, Pacesetter transplant features genemod muscle tissue and modi-
Color Blindness, Night Blindness or No Depth Perception (for fied ventricle construction for greater strength and longer
10 points each). Can add Acute Vision up to +(TL-6), to a maxi- endurance. Say goodbye to cardiac unrest with VeldtKorp’s
mum of +5 (2 points/level). It will also alter the retina print, per- Pacesetter!
haps to match another person’s. – VeldtKorp advertisement
BIOMODS 67
Fine if you want to undergo heart surgery just to get a few about smoking six packs a day. ’Course, that’s nothing – I hear
minor improvements, but I must say I’m personally a teeny bit Navy SEALS have gills these days.
skeptical. I’d suggest waiting until Biotech Euphrates develops – Captain (ret.) Dana Martello, Marine Force Recon
the nanosurgeons to do the modifications without cutting you
open. A little bird tells me they’re working on it in their Cairo Hyper-Lungs comes in both civilian and military (“mil-
facility right about now. spec”) models.
– Chance Mackintosh, Posthuman Consumer Review Statistics: Breath-Holding 1 (2 points), Extra Fatigue +2 (6
points) for 8 points. Milspec model adds Filter Lungs (5 points)
Statistics: HT +1 (cost varies), Extra Fatigue +1 (3 points), and cost 13 points.
Hard to Kill +1 (bonus also applies to Aging rolls and to any Operation: $16,000, or $26,000 if milspec (6 weeks to
rolls made to avoid heart attacks; e.g., from electric shocks or grow, 8 weeks recovery). LC 6.
the Cardiac Stress limitation; +20%, 6 points). Costs 9 points,
plus the cost of +1 HT. Pay for that like any improvement in
HT, except that the doubled cost for increasing HT after initial
Liver Upgrade (TL9)
character creation does not apply. The liver is a chemical factory and purification system
Operation: $28,000 (6 weeks to grow, 8 weeks recovery). where enzymes restructure molecules into substances useful to
the body, and in which detoxification of harmful substances
High-Efficiency Kidney (TL9) occurs. “Team Babylon,” led by Dr. Sayyid Iqbal, is proud to
announce that we have once again improved upon nature. Enjoy
Planning to live as a drylander? You can’t always depend faster and safer metabolization with Biotech Euphrates’ new
on canteens – even the best vapor models can malfunction, forc- liver upgrade!
ing you to rely on stored water. So be safe rather than sorry, – Biotech Euphrates press release
and conserve water the natural way, using a High-Efficiency
Water-Cycle Kidney, from Colonial Genetics. “One of my best hoverjocks had a drinking problem. His
– Colonial Genetics advertisement own business, until he smashed up the rig and lost me six pharm
goats worth sixty grand. So I said if he wanted to keep working
The kidneys filter everything out of the blood and then for me and wouldn’t get a rehab chip, maybe he should make an
selectively reabsorb those substances that your body needs, appointment with Dr. Iqbal.”
while excreting waste material into the urine. There’s some – Eden Harrier, Harrier Import/Exports
waste in the cycle, though, so this modification super-concen-
trates your urine to reclaim as much water as
Statistics: Alcohol Tolerance (5 points) and
possible. Never used one in the desert, but it made
Resistant to Poison (5 points). 10 points.
long road trips a lot more comfortable.
Operation: $20,000 (6 weeks to grow, 4
– Copernicus Jones, Roughing it on Mars.
weeks recovery). LC 6.
Statistics: Decreased Life Support (half nor-
mal water requirement, use bathroom half as often,
10 points).
Perfume Glands (TL9)
New from body designer Lee Pong, with
Operation: $20,000 (6 weeks to grow, 4 chemical coding by Medea Cosmetics. Perfume
weeks recovery). LC 6. your bodily excretions with a neutral deodorant,
or produce one of a half-dozen musks and fra-
Hyper-Lungs (TL9) grances (custom-selected when the glands are
Gain the stamina of an Olympic athlete with ordered).
Colonial Genetics’ new Marathon-series aug- – Noriko Hayakawa, host of Cyberia Beat
mented lung transplants! Specially strengthened
with extra gas-exchange efficiency, human trials Statistics: Generic +1 reaction (Scent-based,
have demonstrated a substantial increase in -20%, 4 points). With a second of concentration,
breath-holding capacity and a boost to overall the user can change between the perfume or
stamina. Perfect for outdoor sports and activities, deodorant, or if desired, go back to his own, nat-
the Marathon is the lung of choice among aug- ural body odor (but an earlier choice will linger
mented professional lifeguards. Various models for several minutes). By changing his scent, the
available, with wide range of custom features. user can also confuse beings that rely heavily on
– Colonial Genetics press release their sense of smell for personal identification
and tracking prey – halve the normal bonus for
The last volume of Jane’s Combat Biomods Acute Taste and Smell or Discriminatory Smell
says the Marathon is standard-issue for the on rolls to identify or track. The effect on other
U.K.’s Royal Marines, with a few extra upgrades, species may be unpredictable!
like a filtration membrane. Now I know why Operation: $8,000 (4 weeks to grow, 2 days
Brigadier Lisa Rutherford-Hodge was so blase recovery). LC 6.
68 BIOMODS
surgery are used to create new nerve connections
Spleen Augmentation (TL9) that enable the modified limbs to be used.
Fresh out of Exon-Horizon’s Barcelona Statistics: These are based on the genemods
genetics lab comes the augmented macrospleen: described under Morphological Changes (p. 39).
An integral part of the body’s defense mecha- Both legs or feet can be replaced with altered
nisms has been further modified to produce limbs (see Modified Limbs, p. 39) and arms can
enhanced versions of disease-fighting white blood be replaced with gengineered wings (see Arms to
cells! Enjoy a longer and healthier life with Exon- Wings, p. 41). The statistics and point costs are
Horizon biotechnology. as described in Chapter 2; the genetically-engi-
neered body parts take 6 weeks to grow.
Operation: This costs $50,000 × (TL-7),
– Exon-Horizon press release
Statistics: Disease-Resistant (5 points) and where “TL” is the minimum TL required for the
Longevity (5 points). 10 points. gengineering. Thus, prehensile toes (TL9) would
Operation: $20,000 (3 weeks to grow, 4 cost $100,000. Recovery time is 8 weeks.
weeks recovery). LC 6.
BIOMODS 69
LC 4.
Polykeratin Disguise (TL11) Sensa-Skin Grafts (TL11)
“Connective tissue throughout your body, and particularly Sensa-skin is artificial, vat-grown living tissue with an
your face, stomach and chest, has been partially replaced by affinity for living flesh. Sensa-skin placed in extended contact
multiple polykeratin grafts and sub-dermal inflatable pouches. with flesh will actually grow into it over time. Sensa-skin makes
With the proper exercises and biofeedback regime, these will biomod transplants simpler and safer, due to its unique ability to
enable you to vary your apparent shape and bulk, and hold this bond with living flesh.
appearance for a short period of time. Additional modifications The effects of Altered Appearance (p. 61), Altered Bulk (only
to your spinal discs allow voluntary compression for a 5% to gain in bulk; p. 62), Extreme Sexual Dimorphism (p. 62),
decrease or 2% increase in height. The polykeratin implants Sex Change (Full Cosmetic or Superficial; p. 62), Skin
have been supplemented by chameleon-like responsive chro- Transformation Virus (p. 78) and Xenosculpting (p. 64) can all be
matophores in all surface tissues, which can slowly alter pig- produced through sensa-skin at TL11+. Treat these as normal sur-
mentation, while your altered hair cells can stiffen or lie flat, gical or transplant procedures, except that there is no “surgery” as
varying apparent length.” such – the sensa-skin is simply carefully attached. There is no
– Dr. Mara Omokage, Omokage Labs need to wait to grow transplants, no chance of rejection and no
recovery time. The application time for a pre-designed sensa-skin
graft is one hour for every week that a normal transplant or
“So, basically, I can look like someone else. But not for surgery would require to recover from. All sensa-skin grafts can
very long.” be removed without surgery up to HT×3 hours after the operation
– Agent Yukio takes place, using the same procedure; after that they are perma-
nently attached and would require surgery to remove.
Statistics: Elastic Skin (Costs Fatigue, 1 point/minute, -5%, For more uses of sensa-skin, see pp. UT95-96.
19 points). At TL12+, Elastic Skin (20 points) that can hold a
shape indefinitely is possible.
Operation: This is treated as surgery. $200,000 (and 8
weeks recovery) for TL11 type, twice that for TL12. LC 4.
Neurosurgery
Surgical modifications to the brain and central nervous sys-
tem may be performed for non-therapeutic reasons, either to
Quadragraft (TL11) enhance the way the brain functions, or more commonly, as a
form of behavior modification. If neurosurgery is performed on
Macrotech Biocybernetics is happy to present the next in its
series of polykeratin implants. Designed for the colonial and someone with the Compartmentalized Mind advantage, the GM
street markets, our transplant techs will replace your arms and should decide whether it will only affect one “compartment” or
legs with patented polykeratin limb grafts. When triggered, your the entire mind. In general, a neurosurgeon who is unaware of
legs become digitigrade (like a dog’s) while your hands trans- the subject’s ability will only be able to affect one of the com-
form into walking paws. Why walk the dog when you can run partments.
with him? Perfect for high-speed scouting and wilderness fun.
Enjoy posthuman thrills with Macrotech Polykeratin!
– Macrotech advertisement
Prefrontal Lobotomy (TL6)
This radical procedure involves destroying the prefrontal
lobe of the brain, which generates certain aggressive tendencies.
My last Earthside hunt was for the killer of two of our mis- Statistics: Prefrontal Lobotomy disadvantage (-15 points).
sionaries, who had been torn apart. I suspected a psycho killer, IQ will also drop by 2 (cost varies). See p. CI93 for other game
but I must say I was caught by surprise when my quarry trans- effects.
formed into a werebeast. It was an interesting fight. After I ana- Operation: $2,000 (and 1 week). LC 4.
lyzed the remains, it turned out he had a polykeratin battle jaw
and some of that high biotech fur. It’s amazing the kind of con-
traband that gets through our blockade.
Killjoy (TL7/8)
– Tisephone Logos, >warangel>heavenweb>solnet This procedure burns out or removes the brain’s pleasure
center, usually via microsurgery.
Statistics: Extra Legs (4 legs) plus Enhanced Move Statistics: Someone who undergoes a Killjoy should replace
(Running) 2, both with Takes Extra Time: two seconds, -10% any disadvantages that drive him to seek physical pleasure (e.g.,
and Nuisance Effects: Horizontal and No Fine Manipulators, Compulsive Carousing, Lecherousness) with the Killjoy disad-
-40%. 13 points. vantage (-15 points), and pay off any point difference. See p.
Operation: $65,000 (4 weeks to grow, 8 weeks recovery). CI91 for other game effects.
This includes four replacement limb transplants. LC 5. Operation: $8,000 (and 1/2 week). LC 4.
70 BIOMODS
two hours on the activity. He becomes Single-Minded while
Brain Tissue Graft (TL8) doing so (+3 to skill if concentration is required). Missing the
Extra brain tissue is grafted onto the frontal lobes to hotshotted activity causes withdrawal. Point cost is variable:
increase the brain’s surface area. The skull is slightly surgically hotshotting may be worth 0 points if the hotshotted activity is
enlarged to accommodate the additional grey matter. Exhaustive something useful, such as a socially-acceptable profession; oth-
brain monitoring and therapy are used to ensure the smooth inte- erwise, it tends to be as self-destructive as any drug addiction –
gration of the brain tissue into the cerebrum and prevent the treat as a cheap, highly-addictive drug (-10 points).
impairment of existing cognitive functions. Continued positive reinforcement will usually cause a hot-
Statistics: Adds +1-2 to IQ (pay for it normally, except that shotted person to develop other disadvantages closely related to
the doubled cost for increasing IQ after initial character creation the focus of his hotshot. This is usually Compulsive Behavior,
does not apply). The bulging forehead is an Unnatural Feature but other disadvantages may be appropriate: Bad Temper (if
(-5 points). If the brain tissue was a transplant from a person (as hotshotted toward combat activity), Lecherousness (if a sex hot-
opposed to vat-grown tissue), there’s a 1 in 6 chance that a few shot) or Workaholic (if the hotshot is related to his job).
“memories” of the original donor may survive. This is reflected A hotshot may also have tertiary effects, at the GM’s dis-
by giving the recipient 1d points worth of the donor’s skills, cretion. Within months of hotshotting, some personalities may
plus the Flashbacks disadvantage (p. CI90). Brain tissue trans- eat less (losing any Fat or Overweight disadvantages and even-
plants from psis may also grant half the psi power of the donor. tually becoming Skinny), neglect grooming (lowering
Operation: $20,000 (2 weeks recovery). Even generic brain Appearance) or talk of nothing but their hotshotted activity
tissue grafts won’t be attacked by the immune system (due to (Odious Personal Habit).
the blood-brain barrier). However, the difficulty of assimilating Operation: $10,000 (and 1 day). LC 4.
new brain matter means de facto rejection is possible – make a Note: This greatly expands on the existing rules for hotshot-
HT-1 roll to avoid it (HT+2 if using fetal brain tissue), with fail- ting (p. CY17). GMs who prefer the original rules are free to
ure resulting in -1 IQ per point the roll failed by. Critical failure continue using them!
causes death within 1d days. LC 5.
Psychosurgery (“Deadheading”) (TL8)
Hotshotting (TL8) Prison? Don’t be a fool. In our country, we don’t have
political prisoners, just sick people who need to be cured. Now
“Your daughter is having trouble with her mathematics
program? She spends all her time in parties, with her boyfriend lie down here and we’ll hook you up to the holographic brain-
or living sensies? Perfectly understandable. These activities are scan. I’ll ask you a series of questions. Won’t talk? Don’t
more pleasurable to her, you see. But we at the Clinic Rouge worry. We can measure your neurological responses, and we’ll
can repair that for you. We will simply rewire her pleasure cen- know exactly which area of the brain to . . . Hold him, nurse!
ter to that part of her brain that governs mathematical and ana- No, I’m not going to “cut” your brain. We once used laser or
lytical activity. As long as your daughter is working on such meson beam cauterization, but we’ve progressed far beyond
problems, she will be excited, even aroused, as if she were with that. I’ll inject cellular microsurgeons, which will operate on
a lover, or eating chocolate. Sign this consent form, and our certain areas of your brain. Your fanatical obsessions will be
operatives will pick her up after school.” cured for good. You’ll become a normal, productive citizen. It’s
– M. Madeleine Rouge, the Clinic Rouge quite painless, and you won’t feel a thing. Never, ever again.
– Dr. Tse Chang, transcript of psychosurgery session
This is a specialized form of psychosurgery. You can get A psychosurgical (“deadheading”) procedure selectively
hotshots for almost anything: cooking, washing dishes, sports, obliterates a tiny area of the brain via micro- or nanosurgery. It
fighting, even netrunning. They monitor you and find the deep is similar to a lobotomy, but orders of magnitude more precise,
structures laid down in the brain as you do things. The result’s enough that it is useful for both behavior modification and ther-
the ultimate in positive reinforcement. Existing reinforcers like apy.
sex or eating can be hotshotted to make them even more plea- Statistics: Deadheading can produce a wide variety of
surable, too. Heck, half the hookers on the strip are sex hot- effects, depending on the surgeon’s skill and desires.
shots, so their pimps don’t even have to buy ’em drugs. I’ve It can destroy any of these advantages: Absolute Direction,
heard some korps will pay an employee a bonus if he agrees to Absolute Timing, Alertness, Ambidexterity, Charisma,
the procedure. Yep, hotshotting makes you happy, eager and Chronolocation, Combat Reflexes, Common Sense, Deep
more productive. It also makes you less human. Sleeper, Eidetic Memory, Empathy, Enhanced Time Sense,
– Professor C. Eric Gideon, sci.bio.posthuman.rant Intuition, Language Talent, Lightning Calculator, Literacy,
Mathematical Ability, Musical Ability, Pious, Rapier Wit,
Statistics: This is treated as an Addiction (p. B30) to the Sensie Talent, Sensitive, Strong Will, 3D Spatial Sense and
endorphins produced in the brain when the hotshot activity is Versatile. It can also lower IQ by up to three points. If Magery
performed. To get his daily fix, the character must spend at least or psionic powers are understood, it may remove them as well.
BIOMODS 71
It can give someone mental disadvantages that represent the recovery). LC 5, or possibly lower if the daemon is dangerous
loss of mental faculties, including: Absent-Mindedness, or antisocial.
Amnesia, Callous, Cannot Learn, Chronic Depression, Clueless,
Combat Paralysis, Confused, Distractible, Dull, Dyslexia,
Gullibility, Hidebound, Illiteracy, Incompetence, Incurious,
Indecisive, Killjoy, Low Empathy, No Sense of Humor, Non-
Tissue Engineering
Tissue engineering consists of surgically implanting syn-
Iconographic,Obdurate, Oblivious, On the Edge, Short
Attention Span, Staid and Weak Will. thetic (but often organic) material to improve the functioning of
It can cure any mental disadvantages except those listed above, living organs, bones or muscles. Instead of replacing flesh the
Prefrontal Lobotomy and Unluckiness. Thus, it could be therapy, way bionics does, tissue engineering aims to enhance it.
removing a Delusion or Phobia. At TL9-10, this must be balanced Tissue engineering uses the rules under Surgery Skill Rolls
by adding a new disadvantage (or removing an existing advantage) (p. 61). As the tissue is synthetic, there is no chance of rejection
from the list above whose point total is worth at least half as much and no need to grow specialized tissues prior to implantation.
as the disadvantage cured. Thus, you could burn Fanaticism (-15 Half of the price buys the tissue, the other half the operation.
points) out of someone’s brain, but you might leave him Confused
(-10 points). At TL11+, deadheading is more precise – it can cure
mental disadvantages as above, but without replacing them with
Muscle Reinforcement (TL9)
“You wish to enhance your strength in a manner that leaves
others. Deadheading can also create targeted (but generalized) no visible traces? You have come to the right place, mon vieux: the
amnesia around specific memories and their associations. Clinic Rouge. Here, the finest nanobots will pleat high-strength
Operation: $1,000 times point change (1 day recovery), elastic fibers into the muscles of your body, using a protein macro-
minimum $10,000. Before psychosurgery can take place, exten- molecule that DuPont Orbital will release next month. Of course,
sive persona mapping is required, requiring a successful we have it now. The Clinic Rouge prides itself on being the cutting
Psychology roll and at least a day of monitoring the subject edge of black medicine.”
(reduce this to an hour at TL11+ and ignore it at TL13+). To – M. Madeleine Rouge, the Clinic Rouge
reverse deadheading, use a biomod or cyberwear that restores
(or neutralizes) the affected advantage or disadvantage. LC 4. “Aussie smuggler, name of Sally
Note: This greatly expands on the existing rules for dead- Strang – maybe you’ve seen her?
heading (p. CY18). GMs who prefer the original rules are free Tiny little redhead with cute braids,
to continue using them! ex-navy hoverjock. Well, we were
walking along the Tokyo waterfront,
Wetware Sub-Personality (TL11) eating squid and talking biz, when
200 kilos of Kobe beef starts hassling
People say I’m too careful, too honest, too soft. I admit I us. Meatboy puts his paws on Sal.
hate the sight of blood, and I’d rather err on the side of caution. Bad move. She grins, lifts him up and
So? It makes me human. But this was too important. The ELF sumoboy goes head-over-heels over
had the Lucifer Plague, and there were only two days left before the rail. Splash! Guess he hadn’t
their deadline. So before I led my team in, I had the GRA labs heard Sally’d gone to Marseille, got-
give me a new wetware sub-persona: the Executioner. ten her muscles done as well as her
– Tatiana Belenko, Genetic Regulatory Agency hair. The meatboy? Hey, you know
what Tokyo Bay’s like these days. The
A development of procedures to treat multiple personality bacteria ate him.”
disorder, this uses neurosurgical and RNA viral techniques to – Eden Harrier, Harrier Import/
construct a sub-personalty – or “inner daemon” – in the user’s Exports
mind. Unlike a Split Personality, this is under his conscious
control. Each daemon has its own set of attitudes, but each also Statistics: Select from +1 to +5
shares the original’s skills, memories and overall goals. ST (or double that if you have skele-
Statistics: Activating an inner daemon causes the user to tal strengthening, p. 81). Pay for it
lose all his normal mental disadvantages, as well as Charisma, like any improvement in ST, except
Collected, Common Sense, Composed, Cool, Cultural that the doubled cost for increasing
Adaptability, Fearlessness, Imperturbable, Single-Minded, ST after initial character creation
Strong Will and Unfazeable. However, any of those advantages, does not apply. Unlike a muscle
and any mental disadvantages, can be included in the wetware graft, weight and looks will not
sub-persona. It is possible to have an inner daemon that simply change when this process is used.
erases all mental disadvantages (“zen state”). The ST increase is cumulative with
An inner daemon takes four seconds of concentration to call other biotech-enhanced ST, but not
up (Takes Extra Time, -20%). It can only remain stable for an bionics. Optionally, characters who
hour or so every day (Limited Use, 1 hour/day, -40%), which is gained +3 to +5 ST from muscle
followed by reversion to the original personality, or a different reinforcement (or +6 to +10 ST,
one. Find the net change in the point value of the character that with skeletal strengthening) can take
was induced by the inner daemon. Then apply a -60% limitation the Unsupported Strength limitation
to this total to find the daemon’s point cost. (p. 138).
Operation: $4,000 times the total cost of all advantages and Operation: $10,000 times char-
absolute value of all disadvantages granted. No cost for erased acter point cost of the added ST
advantages or disadvantages. Minimum cost is $20,000 (1 day (and 3 weeks recovery). LC 5.
72 BIOMODS
Neural Augmentation (TL9) Anabolic Steroids (TL7)
Do you want to move faster than a jack rabbit These are the best-known strength-boosting
on amphetamines? We at Kerensky Labs recom- drugs, synthesized from the natural sex hormone
mend our Max-9 neural augmentation process, testosterone. They have a marked anabolic
which fuses adjacent nerve cells together to (growth-promoting) effect on muscle tissue, espe-
improve the diffusion of neurotransmitters across cially when taken in large doses. That’s why
synaptic junctions and enhance nerve impulse they’re so popular with athletes and body
transmission speed. To ensure optimum perfor- builders who wish to “bulk up” rapidly.
mance, we recommend periodic use of the neuro- Side effects? In spades. Initially, the only
transmitter hormone PK-28N (Pink Noise). effects may seem positive, but continued high
– Kerensky Labs advertisement doses of steroids have a “negative feedback” effect
on the body – it stops making some of its own hor-
They aren’t kidding. Crank yourself up with mones, since it’s getting them from outside. The
the old Max-9 and you move so fast your brain problems associated with prolonged steroid use
can’t handle it without some kind of help. I include sterility, aggression, muscle spasms and
w a s partnered with this ’Maxed-out Russkie pain, and in some cases, cancerous tumors. In
panzerbabe, name of Leona. Greased lightning – men, additional side effects include acne, balding,
or so I thought, until one day when she tripped in a shrinkage of the testicles and breast growth. In
fire fight and shot her foot off. Turned out she’d women, extra side effects are cessation of menstru-
run out of Pink Noise the day before. ation, body hair growth and development of a
– Streethawk, alt.bio.upgrade.samurai more masculine body shape and coarser voice.
To produce a change in strength, large doses
Statistics: Increased Speed +3 (75 points) and of anabolic steroids should be combined with
Total Klutz (p. CI82) unless a dose of drug PK- body-building exercises for a number of weeks
28N ($200/dose) is taken within the week equal to half the character points required to raise
(Mitigator limitation, p. 137; weekly, over ST by one. This produces these game effects:
$100/dose, -60%, -6 points). Costs 69 points. ST +1, HT -1, Extra Hit Points +1 and 3d+5
The Speed increase is cumulative with other lbs. weight increase (all muscle).
sources of this advantage, with the exception of In other words, while a person’s strength and
cyberwear that replaces the organic nervous system bulk increase, his overall ability to resist damage
with electronic systems. stays the same, and his general health declines, rep-
Operation: $330,000 (and 2 weeks), LC 4. resenting the progressive damage that steroids do to
Note: A user can eventually get used to the the body. Moreover, each time ST increases, make
Increased Speed, and buy off the Klutz disadvan- two rolls versus (the new) HT+2, one to avoid
tage using earned points. acquiring each of Bad Temper and Sterile. If the
steroid user has Average or better Appearance, also
roll vs. HT+2 to avoid the loss of one level; like-
Chemical Enhancements
“Ever try Adders? Cute, performance-enhanc-
wise, if the user has the Voice advantage, roll vs.
HT+2 to avoid losing that as well. Women roll to
avoid Appearance or Voice loss at HT, not HT+2.
ing drugs, but they’re pretty limited. Sure, they’ll The same program can be repeated over and
make you smarter or stronger for a few hours, but over again.
then it’s a big letdown. I mean, great for combat or Availability: An anabolic steroid program
acing a test, but that’s not much use if you’ve got a costs about $40 per week. As anabolic steroids
long-term project like a marathon or finishing your (for human use) are grey-market items, LC 5.
thesis, is it? But there’s some drugs out there that Example: Street samurai Gunther Chang (ST
can give you that kind of life-long boost you want. 13, HT 12) decides to increase ST to 14 via
‘Course, your life may not be that long, but at least steroids. Since the difference between ST 13 and
you’ll leave a good looking corpse.” 14 is 15 points, this will take him 15/2=7.5 weeks
– Genosibyl, alt.bio.upgrade.samurai and cost him $300. At the end of this time, Chang
will end up with ST 14 and HT 11/12. He must
GURPS Cyberpunk, Space and Ultra-Tech then roll vs. HT+2 (i.e., 13) to avoid gaining each
describe numerous drug treatments that can pro- of Sterility and Bad Temper, and losing a level of
duce short-term enhancements to human perfor- Appearance. He makes all three rolls – but if he
mance, such as Adders (p. UT97) or Memory-Beta keeps taking steroids, his HT will decline, mak-
(p. UT99). However, it’s also possible to get drugs ing it more likely that he will suffer these effects.
that trick the body into making permanent changes. It’s up to the GM whether characters should
A short selection of drugs of this sort is described pay character points if they increase ST via
below. Feel free to create more, using these as steroids. If so, the cost should be based on the net
inspiration – at TL8+, “designer drug” labs are change. For example, Chang’s ST gain is 15
capable of making a wide range of exotic chem! points, his HT loss is -10 points and his Extra Hit
Note: If drugs increase an attribute, the dou- Point is 5 points, for a total of 10 points. The GM
bled cost for increasing attributes after initial char- could either charge Chang 10 points, or simply
acter creation does not apply. raise his point total by that amount.
BIOMODS 73
Nootropic Drugs (TL7)
These are “smart drugs” (mostly experimental at TL7,
but widely available by TL8) – chemicals that enhance
brain performance. Most smart drugs were originally
designed to treat mental problems, repairing damage to the
brain caused by things like alcohol poisoning, stroke and
senility. They may also fight senility by clearing out cellu-
lar waste products, improving oxygen flow to the brain, or
neutralizing free radicals that interfere with brain function.
In healthy people, they can enhance the ability to grow
connections between neurons, improving the ability to
memorize (which is partially the process of setting up
these connections). Some nootropic drugs also increase
the levels of neurotransmitters that carry electrical signals
from neuron to neuron.
Late-TL7 smart drugs include piracetam, l-dopa and
vasopressin, among others. Most are delivered by pill or nasal This treatment gives +1 Extra Hit Point (maximum). It does
spray. Their long-term effectiveness in healthy people remains not increase ST, but does allow muscle grafting or reinforce-
controversial, but here’s a modest interpretation: For as long as ment to increase ST by two points more than the normal limit. It
the drug is taken daily, and for one day afterward, it allows one can also cure one point of ST or hit point loss due to bone
to buy the Mitigator limitation ($20/week, -65%; see p. 137) for degeneration in zero-G (see Musculo-Skeletal Modifications, p.
any of the following disadvantages: Absent-Mindedness, 42).
Confused, Distractible, Dull, Hidebound, Indecisive, Short Availability: $10,000 (and 2 weeks). Repeated treatments
Attention Span or Staid, and justifies buying off the disadvan- will not have any further benefits, except to cure further ST or
tage whenever the character has the points to do so. hit point losses due to decalcification.
In addition, if the GM feels it is realistic, a character can
buy more IQ, and the doubled cost for increasing IQ after initial
character creation will not apply. To do this he must take
Peter Pan Process (TL8)
“The Clinic Rouge does not advertise this service, but for a
nootropic drugs continuously (and since his last increase in IQ) regular client such as yourself, we will make an exception. Such
for at least as many weeks as the point difference between his a sweet child. How old is he? 11? 12? No, that is not too late –
current and new IQ; e.g., someone with IQ 10 would need 10 as long as he has not left puberty, the Peter Pan process can be
weeks of smart drugs before he could buy IQ 11 for 10 rather initiated. Simply put, our course of synthetic hormone therapy
than 20 points. Side effects are negligible, although hyperten- will ensure certain growth-controlling genes do not switch on.
sion and twitching sometimes occur. As long as treatments continue, he will never enter adolescence.
Availability: $20 per week. LC 5. Eternal youth? Do not mistake me, monsieur. This is not an
immortality process. Organs eventually fail, and after several
Bone Stimulation (TL8) decades, his skin will wrinkle under gravity’s tug, unless cos-
metics or bodysculpt are used. But for the next two or three
Make your bones stronger! This biochemical process stimu-
lates bone cell growth – I heard it’s a development of some of decades, he will be a young boy.”
the technologies the orbitals developed to replace bone decalci- – M. Madeleine Rouge, the Clinic Rouge
fication in zero-G, before they all got their genes twanked to
avoid such mundane problems. “We had the motel under surveillance for dust dealers
– Streethawk, alt.bio.samurai.upgrade when I spotted Mr. Suit heading for a room with a girl who defi-
nitely looked a few years pre-jail bait. Hooking’s legal in this
town, but not with kids. Looked like a righteous bust, so
I blew the door just in time to catch the Vice President of
AresKorp with his pants down. Bad move. Turns out lit-
tle Wendi is 26 years old. Now the D.A. says I’m facing
her lawsuit for false arrest and interfering with licensed
commerce, and the captain says AresKorp wants my
badge. I hate stunties.”
– Detective Cody Chase, Nevada PD
74 BIOMODS
stop growing, many cells switch off. While genetic engineering
Super-Steroids (late TL8) can be performed after the germinal stage, it’s trickier, because
Advanced protein engineering may produce performance- instead of working on a single cell, the body now has billions,
enhancing drugs with similar effects to anabolic steroids (p. 73), each with a different function.
but reduced risk. Genetic surgery cannot produce gross anatomical changes,
After taking super-steroids for half as many weeks as the but it may have subtle effects. For instance, it may alter the way
points required to increase ST by one, gain +1 ST and 3d+5 lbs. a certain hormone is produced, with a marked effect on the
weight. Then roll vs. HT. If the HT roll is a success, there are no recipient’s behavior. At late TL7, genetic surgery is usually
additional side effects. If the roll fails, the user loses one point used to replace defective or missing DNA sequences, repairing
of HT and gains one Extra Hit Point, much as with regular genes so that they can produce whatever missing enzymes or
steroids. If the HT roll is a critical failure (or, if female, any roll proteins caused a genetic disease. At TL8+, non-therapeutic
of 16+), the use also suffers any one of Bad Temper, Sterility, genetic surgery techniques may be developed.
loss of Appearance or loss of Voice, as described for regular Historically, genetic surgery experiments on humans began
steroids (p. 73). in the 1980s with “gene therapy.” Problems were encountered in
Availability: $100 per week. Cost is halved at TL9 and ensuring that the added gene properly interfaced with the body’s
again at TL10+. LC 5. If purchasing these on the street, be wary regulatory system – that is, that it switched on or off when it
of cheaper, old-style steroids with new labels. was supposed to – and it either failed to make the necessary pro-
GMs should usually charge character points for improve- teins or made too much of them. Today (1997), many of these
ment via super-steroids (minus any points lost to side effects). problems have been overcome.
One major genetic surgery technique is the cell transplant.
NERV (TL9) Cells are removed from the appropriate organ of the patient
(e.g., bone marrow cells, if trying to modify how blood is pro-
This drug chemically alters the neuro-endocrine system to duced). Gengineering techniques – usually tailored RNA viruses
improve reflexes and coordination. After taking NERV for half – are then used to introduce new genes into them, as described
as many weeks as the points required to increase DX by one, the in Chapter 1. These altered cells are reintroduced into the
user gains +1 DX. Then he must roll vs. HT. If successful, there patient, where they will hopefully thrive and replicate. At TL7,
are no side effects. If the roll fails, the user suffers one level of the subject is given drugs to help his body accept the new cells
Reduced Manual Dexterity (-3 points/level, p. CI83), as the drug (see Rejection and Immunosuppression, p. 65, for the effects).
increased overall reaction speed and agility but failed to make At TL8+, cell implants are encapsulated in a specialized mem-
the neural connections needed to improve fine motor coordina- brane that masks them from the immune system until they have
tion. If the roll was a critical failure, neural damage was inflict- become safely integrated into the body, while still allowing pro-
ed due to an accidental overdose, and (1d/2)+1 levels of teins to pass through – the advantage being that no immunosup-
Reduced Manual Dexterity are suffered instead of one level. pression treatments are needed. In some cases, the controlled
Availability: $2,000 per week. LC 5. “Street NERV,” at release of cells is orchestrated by biochips (p. 138).
half cost, is similar – but there is a -4 on the HT roll to avoid In some cases, actually removing cells to work on them
side-effects. may not be necessary, and a modified RNA virus can simply be
injected into the patient. This largely depends on how specific a
Genetic Surgery
Humans begin as single cell – a zygote – but as we grow out
change needs to be made, and how confident the genetic sur-
geons are in their ability to target the specific cells they want to
alter.
of the germinal stage, our cells differentiate. Every cell carries Genetic surgery processes have a listed cost and time. The
the full complement of genes, but it only uses some of them, required time is spent in a hospital facility. During this period,
depending on where it is in the body. This is what distinguishes genetic surgeons are taking cell samples, running tests, perform-
skin cells, brain cells, blood cells and so on. The function of the ing the actual RNA injections or cell transplants (often a series
genes in a cell may also change over time; for instance, after we of them), waiting for modified cells to replicate, observing the
BIOMODS 75
results, and taking any necessary corrective mea-
sures. The patient will be confined to bed (often Emotional Regulator (TL8)
with diagnostic sensors attached), but is conscious Get into too many bar fights? Suffer from poor
most of the time. impulse control? Then you’re the kind of personali-
So what can you do with genetic surgery? ty that can use a Jen-Goku Rage Damper! Unlike
Some of the many possible applications are cruder systems, this bio-implant doesn’t prevent
described below. you from feeling emotions. Instead, this cluster of
biochip-regulated cells is capable of sensing hor-
Gene Therapy (TL7/8) mones and follows them up with tailored enzymes
that cut them off at the pass.
If someone is born with faulty or missing – Jen-Goku Corporation advertisement
genes, the body may lack the capability to make
enzymes or other proteins that it needs. Depending “Joji ‘Madboy’ Saiko got one of these cell
on which genes are missing, this deficiency may transplants after his last assault conviction. Was it
cause a hereditary metabolic disease, such as cystic a court order? Not this time. The Oyabun’s deci-
fibrosis or hemophilia. There are almost 3,000 such sion. The Russki-Yakuza don’t admire a man with
genetic disorders. no self control. Besides, Jo had run out of little fin-
In fact, most humans and other animals carry a gers.”
few defective genes. However, humans and similar – Eden Harrier, Harrier Import/Exports
higher animals have two duplicate sets of almost
every chromosome and the genes they carry, one Statistics: Hormonal dampers can justify buy-
from each parent. (The exception is the male “Y” ing off Bad Temper, Berserk or Lecherousness;
chromosome; as a result, men are more vulnerable point cost is equal to the cost of buying off the dis-
to “sex-linked” disorders resulting from defective advantage.
genes on either sex chromosome.) Even so, genetic Operation: $4,000 (and 1/2 week to recover,
disorders affect as much as 10% of the human pop- although it takes effect within 1 day). LC 5.
ulation, although the effects of some do not mani-
fest until quite late in life.
Until the late 20th century, the symptoms of
Bone Marrow Upgrades (TL9)
genetic disorders could be treated, but the disorders When I completed boot camp, the fun began.
themselves could not be cured. Thanks to an After they finished growing the new muscles, the
advance in bioengineering called gene therapy, is doctors implanted modified cells into my bone mar-
now possible to remove the root cause of a genetic row, altering it to manufacture erythrocytes with
disease using cell transplants (p. 75). Even so, a boosted oxygen-transport capacity. Of course, then
basic limitation on gene therapy is the need to they had to do a bit of tinkering with my gastroin-
know exactly which genes code for which enzymes testinal tract to make sure I got enough iron from
or proteins, and how they relate to the body’s func- our diet to keep my bone marrow happy . . .
tioning. While considerable progress has been – Captain (ret.) Dana Martello, Marine Force
made in cases involving a single gene, multiple Recon
genetic interactions are often involved. As human
Bone marrow cells may be modified to pro-
genome mapping progresses (through TL8), more
duce gengineered blood cells with improved capa-
complex genetic therapy procedures will become
bilities. Care is taken to ensure that the modified
possible.
marrow is “smart” enough to adjust cell production
Statistics: Gene therapy can remove certain
so that complications like high blood pressure and
disadvantages, if they result from hereditary condi-
other disorders do not occur.
tions. By late TL7/early TL8, this includes some
Statistics and Operation: These depend on the
forms of Hemophilia, Terminally Ill and Weak
type of blood cells that are modified:
Immune System. By mid-TL8, it also includes
Enhanced Erythrocytes: The bone marrow is
Epilepsy, Migraine and Tourette’s Syndrome.
modified so that the red blood cells it produces
During TL8, all genetically-caused forms of
possess hemoglobin with greater oxygen transport
the above conditions can be cured gradually. In
capacity. Gives Extra Fatigue +2 (6 points).
addition, in a fetus or young child, early gene thera-
$12,000 (and 2 weeks). LC 5.
py may be able to prevent Bad Sight, Color
Enhanced Thrombocytes: Blood platelets are
Blindness, Dwarfism, Dyslexia, Gigantism and No
redesigned for superior wound-clotting ability.
Sense of Smell/Taste.
Gives Very Rapid Healing (15 points). $30,000
Also at some point during TL8, gene therapy
(and 3 weeks). LC 5.
may be able to cure inherited learning or behavioral
disorders. Where these disadvantages have a genet-
ic cause, they can be removed: Cannot Learn, Metabolic Reset (TL9)
Chronic Depression, Gluttony, Lunacy, Manic- “Back in prehistoric times, people used lipo-
Depressive, Non-Iconographic, Paranoia, Short suction and surgery to remove fat, or took pills to
Attention Span and Slave Mentality. suppress their appetites. No, really! And after-
Operation: $10,000 per disadvantage cured wards, they often went right back and regained
(and 2 weeks). LC 6. what they lost. Today, we know what genes make
76 BIOMODS
your body want to be a certain weight, and how to make RNA is the number of days it takes the virus to replicate throughout
injections to change them.” the body and finish its work; there is no “operation” – one mere-
– Noriko Hayakawa, “Fun Ways to Change Weight,” ly takes a pill or receives an injection. Unless using a metamor-
Cyberia Beat phosis virus (p. 79), no rest is required – the nanovirus performs
the work quietly and without fuss.
Statistics: Bulk can be altered up or down one or more Various customized forms of proteus virus are also possible,
steps: Very Fat (-20 points), to Fat (-10 points), to Overweight such as a nanovirus that spreads like a plague or which is specif-
(-5 points), to normal, to Skinny (-5 points) or vice versa. ically designed to affect a particular person (which means that
Adjust weight in pounds accordingly. Lose or gain one step his immune system has less chance to resist it). See Proteus
every two weeks until the chosen stage is reached. Halve the Virus Options, p.82.
time if the subject works with the virus via diet and exercise (or
lack thereof); double the time if he tries to fight it!
Operation: $4,000. The reset operation itself requires 1/2 a Growing Nanovirus
week, but losing (or gaining) weight takes the time discussed A proteus virus designed to produce a particular biomod (or
above. LC 6. a set of nano-symbiotes – see p. 84) can be “home grown”
rather than purchased. This requires a genetics lab (p. 21) of a
BIOMODS 77
Hacking +3 (only with biotronic computers, -50%, 4 points);
Enhanced Time Sense (45 points, only when interfaced with Genetic Surgery Nanovirus (TL10)
biotronic computers -75%, 12 points). 22 points. Any of the effects that can be produced by regular TL7-9
If using the GURPS Cyberpunk netrunning rules, effective genetic surgery (pp. 75–77), such as gene therapy or metabolic
phase length is halved when someone with this ability is netrun- reset, can be produced much more rapidly via a proteus
ning while jacked into a biotronic computer. nanovirus.
Availability: $200,000 (and 4 days). LC 2. Statistics: Produces the same effects as regular genetic
surgery.
Birth-Control Virus (TL10) Availability: Cost is 50% that of TL9 genetic surgery proce-
dures or 25% that of TL7-8 genetic surgery. The virus will pro-
“If the Third World can’t be bothered to control their own duce the changes in a number of days equal to twice the number
fertility, then I suppose we’ll have to do it for them. Let’s see: of weeks of recovery required for actual genetic surgery. For
birth control implants, vasectomies, pills . . . but they’re all so example, a bone marrow upgrade that took 3 weeks would take
crude and time consuming, and then there’s that problem of only 6 days if using a nanovirus.
enforcement. How about isoimmunization, in which the moth-
er’s immune system attacks any fetuses, triggered after the onset
of her first pregnancy? Spontaneous and usually undetectable Methuselah Program (TL10)
early abortions; she’d probably never notice. One woman, one Methuselah Inc. is pleased to offer its new life-extension
child. As for mass post-natal dissemination, a contagious pro- process. A specialized proteus nanovirus injection can adjust or
teus virus should do the job.” even reset the biological clock on your cells, modifying their
– Dr. Tse Chang, address to the Genetic Planning Council ability to survive repeated replications. In partnership with
Biotech Euphrates, our Forever Project staff is now working on
Statistics: Sterile (after one child, -75%, -1 nucleotide sequences that will hard-wire these
point). modifications into unborn generations.
Availability: $500 (and 2 days). LC 5. – Methuselah Inc. press release
78 BIOMODS
Statistics: Select any one of the xeno-skin advantages listed Last year, Evolutionary Liberation Front terrorists hacked
on the Xeno-Anatomy table (p. 50). into the mainframe controlling the labeling on 2,000 vials of
Availability: Cost is (TL-8) × $20,000, and it takes (TL-8) Chinju-Gentek RNA virus. 127 people who hoped to become
weeks for the skin transformation to take effect, where “TL” is musicians, many of them children, were instead transformed
the minimum TL for gengineering that advantage. Thus, Fur (4 into mathematical geniuses, and 1,873 would-be Einsteins were
points, TL9) would take one week to grow and cost $20,000. left to sing the blues. The relationship between mathematical
Undergoing a skin transformation process is extremely uncom- and musical talent was close enough that the quality-assurance
fortable. For the duration of the process, the subject will be at -2 software missed it. Bio-terrorism aside, this is obviously anoth-
DX and IQ (which affects skills) due to the constant itching and er example of the need for tighter controls in the civilian RNA-
irritation as the fur or scales grow. nanovirus sector.”
– Tatiana Belenko, Genetic Regulatory Agency
High-Biotech Fur (TL11) A “neurovirus” is a specialized form of proteus virus, opti-
Colonial Genetics’ ShonTec/Mars division announces the mized for performing subtle changes in personality and mental
arrival of viral-grown high-biotech fur, the ultimate in stylish structure by altering the connections between neurons and
thermoregulation! Features fully-retractable, sub-dermal, self- adjusting the neurochemical balance of the brain and body.
regenerating pseudohairs. Choose no or short fur for indoors or Statistics: A neurovirus can modify IQ up to the technologi-
summer, but lengthen it as night begins to fall, then retract it as cal limits given for Gengineered Attribute Modifiers (p. 30),
temperatures return to normal. Why bother with bulky thermo- grant any of the advantages described under Brain
suits or even outmoded clothing? Perfect for outdoor condi- Modifications (p. 32) and Sleep-State Modifications (p. 33), and
tions, and presently available in numerous attractive patterns, add any of the genetic mental disadvantages from the Mental
including tabby, mink, panda, leopard and Disadvantages table (p. 53). It can also duplicate
tiger! effects of Psychosurgery (p. 71) or Hotshotting (p.
– Colonial Genetics press release 71). Where they contradict, more recent neuroviruses
overwrite previous ones.
“My sources at ShonTec say they origi- Availability: $10,000 × (TL-7) per advantage or
nally designed this feature as a post-natal disadvantage, where “TL” is the minimum TL
upgrade for the 6th Mountain Division’s required for that procedure. Requires 1/2 day to take
bioroids, so it’s probably pretty reliable. It’s effect. LC 5.
also available on their second-generation
pleasure ‘morphs. Have you seen those ads?
‘Stay warm at night: Take a Kitsune to bed.’”
– Captain (ret.) Dana Martello, Marine
Metamorphosis Virus (TL12)
“Captain’s Log, 18-11-2447. It’s been six days
Force Recon
since our landing party was exposed to the nanovirus
Statistics: Thick Fur (variable length, while exploring the ruined alien city. All remain in
+5%, 31 points). Length can voluntarily drop comas, within the cocoons their bodies have some-
to that of normal Fur (two seconds), Very Thin how secreted. Sonograms taken by Dr. Pretorious
Fur (four seconds) or completely retract (eight show significant anatomical changes, of which the
seconds), or vice versa. Remember, PD, DR most advanced are in Officer Melinda O’Reilly. Her
and Temperature Tolerance vary depending on legs have fused together into a tail, and wing buds
length. Very Thin Fur counts as light clothing. are forming on her shoulder blades. I can no longer
Availability: $40,000 (and 2 weeks), LC 5. deny it; she is beginning to resemble the creatures
Side-effects of the high-biotech fur transfor- depicted in the wall paintings we found. In an earlier
mation are the same as for other skin transfor- log entry, I expressed my sadness at finding the aliens
mations. long dead, and being denied a chance at first contact.
It appears I spoke too soon.”
Neurovirus (TL11) – Captain Zeke Morrigan, free trader Antares
BIOMODS 79
herd cells around the body, kill off existing
ones, and force new ones to grow. This allows it
to break down or build up connective tissue and
The Transformation
The nanovirus takes the indicated number of
bone. Using a metamorphosis virus, new organs days to transform its subject. If the subject has a
can be grown within the body, existing organs particular feature, it won’t need to grow it, so
and limbs can be transformed, and new limbs reduce the transformation time accordingly (i.e., as
and appendages can be grown. A metamorpho- if the virus didn’t include that particular trait).
sis can even reduce body mass (leaving a gooey This also applies to attribute bonuses or
puddle of unused cells after the change). penalties that were created via gengineering (as
In game terms, a metamorphosis virus opposed to those native to a particular race). If the
effectively allows the type of human genetic nanovirus adds a bonus and there’s already a
engineering described in Chapter 2 to be per- bonus, use the higher number; if the nanovirus
formed on a living person rather than an egg adds a penalty and there’s already a penalty, use
cell. The virus is described as adding or remov- the lower value; if the nanovirus adds a bonus
ing a specific set of attribute modifiers, advan- where there’s a penalty or vice versa, use the sum.
tages, disadvantages and features – a “metamor- Thus, if someone already has ST +2 as part of a
phosis template.” Select from those modifica- gengineered racial template, then a nanovirus that
tions that are possible via germline gengineering gives ST +1 to ST +2 will have no effect, one that
(Chapter 2) or surgery (Chapter 3). The time gives ST +3 will change his racial template from
and cost of a metamorphosis virus depend on its +2 to +3 (the character gains +1 ST), and one that
complexity: gives ST -1 will alter his racial template from ST
+2 to ST +1 (the character loses one point of ST).
Time: This is (TL-8) days per advantage, While the metamorphosis is occurring, the
disadvantage or feature added or removed, patient may experience “nanofever” – itching, sud-
where “TL” is the minimum TL required to pro- den sweats, hunger pangs or other odd sensations.
duce that change through gengineering or Often, he sees odd shapes and patterns forming on
surgery. For this calculation only, treat any TL his skin, or suddenly feels hungry, thirsty, hot or
below 9 as TL9. Purely cosmetic traits that are cold. This is distracting (-1 to IQ-related tasks dur-
part of an advantage or disadvantage don’t ing the entire process).
count; otherwise, they count as a single, TL9 If the change is radical, defined as any
feature. process that takes more days than the nanovirus’
For example, a “cat-girl nanovirus” might TL, or which induces significant alterations in
have seven traits which require up to TL9 (e.g., body shape or mass, the subject will fall into a
Acute Hearing, Beautiful Appearance, Claws, coma after 1d days. This lasts for the remainder of
Fur, Perfect Balance, a male-to-female sex the transformation. If this happens, the nanovirus
change and transgenic cat features) and one that will often secrete a caterpillar-like chrysalis from
needs TL10 (e.g., DX+4). It would require [(9 -
8) × 7] + (10 - 8) = 9 days. Note that in practice,
the patient’s skin pores or other orifices, cocoon-
ing his body. When the transformation is com-
time may be reduced if the subject already has plete, he will wake up and break out of it.
certain traits; e.g., if the cat-girl nanovirus were A metamorphosis nanovirus is not always
used on a woman, it would take only 8 days. safe. If the virus takes more days than the sum of
the user’s HT and the virus’ TL, there is a chance
Cost: Calculate time as above, then multiply the number of that something will go wrong. Each day after this period, roll vs.
days by $50,000 to get the cost. Thus, a virus that requires 9 the user’s HT. Failure means some sort of accidental defect.
days would cost $450,000. Keep track of the number of failures. Each one inflicts -1d
points worth of unintended disadvantages on the subject (GM’s
TL: The basic TL of a metamorphosis virus is the greater of option; see Gengineered Disadvantages, p. 51, for a list of suit-
TL12 and that of the highest-TL modification that it adds or able possibilities). For example, failing three HT rolls would
removes. inflict -3d points of disadvantages.
Any critical failure means the subject dies – often very
A “dose” of the virus can be delivered by injection or oral messily, as the patient transforms into a mass of cancer cells, is
tablet. The rules for administration, HT rolls to resist and acci- cooked in his own blood by excess heat from over-worked
dental infection used for other proteus viruses (p. 77) also apply nanomachines or whatever.
to a metamorphosis virus. Any of the proteus virus options Cybernetics or biomod implants that would be incompatible
described on p. 82 can also be applied to it, altering the final with the new form are excreted from the body or result in death
cost, time and TL. or injury to the subject – details are up to the GM.
80 BIOMODS
Sample Metamorphosis Word of warning: If you become pregnant in
female mode, you’ll automatically switch back and
be locked into female morphology about a week
Transformations into the pregnancy unless you voluntarily choose to
reabsorb the fetus, like I did.
Practically any transformation is possible with
the aid of a metamorphosis nanovirus – for – Chance Mackintosh, Posthuman Consumer
instance, it could turn a human into any of the vari- Review
ant races described in Chapter 2, make him into an
alien, transform an alien into a human, or give Statistics: Hermaphromorph (2 points) plus
someone any of the biomod surgeries or transplants Reproductive Control (2 points). 4 points.
in this chapter. This section provides additional Availability: $150,000 (and 3 days). LC 5.
examples of complex anatomical modifications
that might be produced through metamorphosis. Skeletal Strengthening (TL12)
The time listed for metamorphosis transforma- “Tisephone Logos, if you closely look at the
tions assumes that the subject does not have any of image produced by my T-ray scanner, you will
the traits that the nanovirus produces. clearly see the changes the nanosurgeons have pro-
duced in your body. Note the semi-fullerine skeletal
Aquaskin (TL12) structure and extra muscle attachment flanges,
while the dark shading is the denser bone tissue.
Who needs a breather, wetsuit or clumsy arti-
ficial gill? Glide like a dolphin through the blue None of this will be visible unless your skeleton is
infinity while clad in GenTec Pacifica’s Aquaskin, physically examined or scanned, although you will
a smooth, high-biotech epidermal graft derived notice a minor gain in mass due to the heavier
from marine mammal DNA. The skin is modified to structural tissues you now possess.”
selectively absorb and filter oxygen into the blood, – Medical biocomputer Raphael-3000
bypassing the lungs and acting as a full-body gill.
Available in several elegant shades of gray, brown Statistics: Extra Encumbrance (5 points) and
and black. Extra Hit Points +9 (45 points). 50 points.
– GenTec Pacifica promotion Skeletal strengthening increases actual body
weight by 10% without increasing height or appar-
Statistics: Amphibious (10 points) and Gills ent bulk. The redesigned bone structure will also be
(10 points). 20 points. noticeable on medical scanners, and by any doctor
The smooth, monochrome skin and webbed trying to set a broken bone. Skeletal strengthening
fingers and toes may count as an Unnatural Feature does not increase ST. However, if someone has
(-5 points). skeletal strengthening, then muscle reinforcement
Availability: $150,000 (and 3 days). LC 5. or muscle grafting can add double the usual amount
of ST for their TL, since the biomod skeleton can
Chloramorphosis (TL12) support it. The effects are cumulative with bone
stimulation (p. 74).
The green-skinned woman lay naked in the Availability: $250,000 (and 5 days). LC 5.
forest clearing, as if basking in the warm, noonday
sun. I walked over and knelt beside her. If she was
breathing, I couldn’t tell. An ant walked across her
Smart Cardiovascular Net (TL12)
face. She didn’t react. I looked closer. Fine tendrils Next, the nanites construct smart, switchable
connected her body to the soil. She was rooting. arterial bypass networks to allow blood flow to be
– Derin Skay, Life Among the Dryads rapidly shut off to traumatized areas. As high-grav-
ity accelerations cause blackouts when the blood
Statistics: Decreased Life Support (breathe pools in the lower body rather than reaching the
carbon dioxide rather than oxygen when sleeping, brain, the arteries feeding the lower body have
10 points), Deep Sleeper (5 points), Dependency been redesigned to react to g-forces by pinching off
(lie in fertile soil and sunbathe for at least eight blood flow to legs and abdomen while enhancing it
hours; common, daily, -15 points), Doesn’t Eat or to the brain. The same modification also produces
Drink (10 points), green skin (racial feature, 0 faster recovery from unconsciousness.
points). 10 points. – from FM-592, Military Biomedical
Availability: $400,000 (and 8 days). LC 5. Enhancement
BIOMODS 81
Statistics: Acceleration Tolerance (+5 HT bonus from it
may also be applied to HT rolls to stop bleeding, +40%, 14
points) and Recovery (10 points). 24 points.
Proteus Virus Options
There are lots of ways that the basic proteus virus technolo-
Availability: $150,000 (and 3 days). LC 5.
gy can be modified.
Solarskin (TL13) Accelerated Nanovirus (TL12)
Freedom is the gift our Icarus-type symbiotic solarskin
gives when you merge with Avatar Klusterkorp’s gengineered “You mean I’m going have to wait days or months for the
ecosuit to become a true spacedapted form. Features closed- nanovirus to grow my new face and improved heart? I got tick-
ecosystem waste-product recycling, solar wings and vacuum- ets to go skiing on Nix Olympica two weeks from now – but I
sealed skin designed for protection against ultraviolet radiation. can’t go like this – I’m not in shape! What the fooz am I going
– Avatar Klusterkorp advertisement to do?!”
“Well, if you’re that desperate, there’s a black clinic that
Naked, space-black dolls with enormous pseudo-wings, might be able to help you . . .”
drifting through the vacuum on light pressure like dark angels: – Dr. Lucien Locke, Nanovirus for Dummies
Avatar’s latest vision of humanity, I guess. The one disadvan-
tage is that you croak in a gravity field. You aren’t anaerobic, A nanovirus normally takes it slow and easy, because herd-
though, so you can hang with your buddies inside the null-G ing all those cells around and forcing growth is a major strain on
section of a ship or station when you aren’t “breathing vacu- a living being’s metabolism. It doesn’t have to be this slow.
um.” At least they designed it so you can fold up your solar sail At double cost, and a minimum TL12, an accelerated pro-
when you don’t need it – makes a hump on your back. teus nanovirus is available. An accelerated nanovirus takes
– Copernicus Jones, Beyond Pluto hours instead of days. For example, if it normally took two
days, the accelerated virus would do it in two hours. At TL15+,
Statistics: Flight (Requires Low Gravity: 0 G, -50%; Space it may be even quicker, taking as many minutes as days.
Acceleration: 0.001 g, +5%; 22 points), Vacuum Support (40 If using any proteus virus, the accelerated growth process is
points), Weakness: 0.05 g or higher gravity field, very common, stressful. The user will experience “nanofever” symptoms, as
1d/minute (-60 points). 2 points. described for metamorphosis virus (p. 80). In addition, the user
Availability: $500,000 (and 10 days). LC 5. will suffer one point of fatigue each hour, until he passes out
(he’ll be unable to rest to regain this until after the virus has run
its course).
If using a metamorphosis virus, it’s often dangerous as
well. Use the same rules for side effects (p. 80) as for a normal
metamorphosis virus, but occurring if the virus takes more
hours (rather than days) than (HT+TL-5). In addition, HT rolls
to avoid suffering side effects are made at HT-3 rather than HT.
Get too ambitious, and there’s a good chance of a messy death.
Clinical Metamorphosis
“Uh – a messy death? ’Scuse me, Dr. Luce, I’m outta here.
Isn’t there a way the virus can grow a new part safely?”
“It isn’t the virus that doing the growing, livewire; it’s
directing things. It’s your cells that are doing the work.
Remember, it’s got to keep you alive. Imagine trying to do
repairs on a car while the engine is running – heck, while
you’re still driving the thing around.”
“Okay, okay – so why not stop the engine first? Or do the
work from outside the car – I mean, the body?”
“Ooh, good one. Let’s try it.”
– Dr. Lucien Locke, Nanovirus for Dummies
82 BIOMODS
Next, the patient is put into a state of complete bio-stasis,
similar to suspended animation. A solution of specialized
nanomachines is pumped into the tank with him. Some of these
“nanobots” may be similar to a nanovirus, while others might be
actual robots, either autonomous models or guided externally by
a controlling computer, perhaps using acoustic pulses. These
nanomachines are in charge of keeping the subject alive and
speeding up the transformation by working both internally and
externally.
Once the patient is in bio-stasis, more radical nanosurgical
procedures can be used. If body mass is to be altered, intra-
venous tubes may be attached to the body and the necessary
materials carted in or out by transport nano. Some tubes, made
of nano-active material, may penetrate directly into the patient’s
body without breaking the skin. In radical transformations, the
patient may actually be dismantled on the cellular level, turning
him into a loose “puddle” of cells, then reassembled.
The process takes the same amount of time as an accelerat-
ed nanovirus – or half the time, if using a chrysalis machine –
but it’s completely safe (assuming no sabotage and no glitches
in building and programming the nano). After the operation is
over, the nanomachines will break up; their debris leaves the
body via sweat or excretion. However, while it may be safe, this
process isn’t cheap: in addition to the usual price quoted for
metamorphosis nanovirus, the life-support system and special-
ized nano used cost a minimum of $3,000 a day. Delayed: The nanovirus is designed with a time delay.
Instead of taking effect within a few minutes of infection, it
Other Proteus Virus Options remains dormant for a pre-set time period after infecting some-
“Hey, Doctor Luce – this proteus nanovirus stuff – isn’t it one – anything from hours to years. This option has no effect on
supposed to, you know, go out of control infecting and trans- cost or TL, but the dormancy period must be chosen when that
forming everyone, and like that?” particular batch is designed.
“Of course not. Not unless you design it to. Here’s how.” Heredity-Changing (TL-1): The nanovirus has no effect on
– Dr. Lucien Locke, Nanovirus for Dummies the person it transforms – no twinges, sweats, coma or biomodi-
fication! However, it does alter genetic heredity, and the effects
Various options are available to change the way in which a will be passed on to the subject’s children. Since children have
particular nanovirus works. Unless noted, these may be applied genes from both parents, inheriting virus-induced traits is much
to all procedures that use proteus virus, including metamorpho- more likely if both parents have been infected by the nanovirus.
sis virus. These will modify the price and tech level of the Inorganic (TL+1): The “virus” is composed of inorganic
nanovirus, as shown in parentheses. nanobots rather than biological machines. HT rolls to resist
Note that a change in TL also has an indirect effect on infection are made at a -2 penalty. Panimmunity, Disease-
price. For example, if a neurovirus is normally available at Resistant, Immunity to Disease and similar measures intended
TL11, but is modified with the Plague option, then it is TL12; to defeat biological pathogens have no effect against it!
therefore, the price of that particular neurovirus would be halved Plague (TL+1, 10 times price, or 100 times price if
at TL13 and again at TL14, rather than at TL12 and again at Inorganic): The virus can spread through skin contact and via
TL13. breathing infected air. Anyone in direct skin-to-skin contact
with a person who has been infected but not yet transformed can
Aerosol (10 times price): The nanovirus doesn’t require catch it on a HT-3 roll, or HT-6 if they exchange bodily fluids.
injection. It can be used in a chemical warhead or aerosol spray. For close proximity, use the rules from the Contagion sidebar,
It uses the normal rules for biochemical weapons, and affects p. B133. Plagues are LC 0.
anyone who breathes it and fails a HT-6 roll. At TL+2, it may Random Metamorphosis (TL+2, special price): This has a
be a contact agent, penetrating the skin of anyone exposed on a semi-random series of effects on different subjects. It may give
HT-3 roll, or HT-6 if also breathed. An aerosol can will spray 1 one person an exotic biomod, transform another into a different
dose at a time and holds five; 10 doses fill a chemical grenade, form, change a third person’s sex, and so on. The GM should
30 fill a mortar shell. Halve LC (round down). decide what percentage of victims suffer what type of effects,
BIOMODS 83
whether there are any other side effects, and the maximum pos-
sible character points of change. Cost is up to the GM, but
should be based on the maximum number of points that can
Nano-Symbiotes
Symbiotic, pseudo-living nanomachines or genemod pro-
potentially be changed. The Wild Cards shared world series
(edited by George R.R. Martin) features a good example of such teus cells can be introduced into the body, usually by injection.
a virus. Instead of being used to build or alter something, they take up
Species-Crossing (TL+1, 10 times price unless Inorganic, housekeeping.
then double price): Nanoviruses are generally effective only on The process of administering nano-symbiotes is identical to
a single species (and any variant races thereof) or a few closely- that for proteus virus: an injection or tablet – ideally, one that is
related ones – this is more a matter of programming in the case matched to the person’s metabolism. There are no side effects,
of inorganic nano. A virus that works on humans won’t affect since they don’t alter the body, but simply exist within it. Here
cats or dragons, for instance. This modification makes it pan- are few possible examples of nano-symbiotes:
specific, capable of affecting multiple species provided they
share the same basic biochemistry. Thus, a nanovirus designed Panimmunity (TL9)
to affect terrestrial life probably won’t work on aliens, unless Panimmunity injections contain artificial organisms, tailor-
there’s a good reason (e.g., if by sheer coincidence or design, made for each individual. They recognize friendly cells, and
we are amazingly genetically similar to them). attack others. Panimmunity is permanent.
Target-Specific: A nanovirus can be designed to target specif- Statistics and Availability: Depend on the bioengineering
ic characteristics; see Target-Seeking Pathogens (p. 89) for possi- techniques of the society:
ble designs. A Plague may still be target-specific – people other Level 1 Panimmunity (TL9): Gives +3 to HT to resist any
than the target(s) will become carriers if they fail HT rolls, but disease. $1,000. LC 6. 2 points.
suffer no other effects. This option has no effect on cost or TL. Level 2 Panimmunity (TL10): Gives +8 HT to resist any
Temporary: A neurovirus (p. 79) can be designed to pro- disease. If this is not universal, cost is $5,000. Citizens in TL12
duce only temporary effects by interfering with neurochemistry societies may receive Level 2 panimmunity free through gov-
and hormonal balances rather than altering the structure of the ernment or corporate health plans. LC 6. 5 points.
brain. The effect will last for a number of hours equal to twice Level 3 (Total) Panimmunity (TL12+): Gives the recipient
the amount the initial HT roll to resist was failed by (maximum the equivalent of the Immunity to Disease advantage, with no
one day). This sort of nanovirus is often used as a form of brain- minimum HT required. It costs $20,000 – although it might be
washing or biochemical weapon. This option has no effect on provided free in organizations like the Survey Service. LC 6. 10
cost or TL. points.
Xeno-Species Crossing (TL+2, 20 times price, Inorganic
only): Capable of crossing between extremely different forms of
life, such as terrestrial and alien life forms. Xeno-Species
Blood Cops (TL12)
Crossing nanoviruses may still not work if the aliens are very In my darker moments, I feel my bloodstream has turned
alien; e.g., a virus designed to work on carbon-based life into an arms race. They told me this is like Panimmunity 3 but
wouldn’t affect silicon-based “living rocks.” Given the (proba- more expensive: Inject a few trillion gengineered macrophage
ble) drastic differences expected between human and alien life, cells into your body, and these “active shields” will hunt down
a Xeno-Species Crossing nanovirus is more cinematic than real- and dismantle anything that looks threateningly pathogenic or
istic, but is nevertheless very common in science fiction. toxic before it can do much in the way of damage. It seems to
have worked – I haven’t aged or gotten sick since the proce-
dure. Considering some of the places I’ve been, this is surely a
Nanowarfare miracle.
The ability to create plague proteus viruses raises the spectre – Tisephone Logos, >warangel>heavenweb>solnet
of exotic nanoplagues that transform rather than kill. For
example, imagine spreading one that turned humans into
compliant sex bioroids (like the Eros, p. 37). The threat
of proteus plagues is somewhat lessened by the avail-
ability of sophisticated Panimmunity treatments,
although these are ineffective against inorganic
nanoviruses. However, humans don’t have to be the tar-
get – imagine the havoc that even a “benign” intelli-
gence-boosting neurovirus could cause if a species of
pets, farm animals or wild animals became more intelli-
gent! In fact, targeting nanoplagues at animals may be a
viable surprise attack strategy, if humans have gengi-
neered defenses.
84 BIOMODS
Statistics: Immunity to Disease (10 points),
Immunity to Poison (15 points) and Longevity (5
points). Costs 30 points.
Availability: $30,000, LC 6.
BIOMODS 85
4 MAN’S BEST
FRIENDS
And God said, Let us make man in our image, after our
likeness: and let them have dominion over the fish of the sea,
and over the fowl of the air, and over the cattle, and over all the
Exotic Industrial Bacteria (TL7/8)
Not all “working bacteria” are involved in fermentation or
earth, and over every creeping thing that creepeth upon the protein farming. There are bacterial species which are naturally
earth. capable of metabolizing metals or chemical waste, are resistant
– Genesis 1:26 to heat (even living in ocean vents) or are anaerobic (don’t
require oxygen). These have various applications, such as:
Human gengineering is controversial, but the modification
of plants and animals is much less so. We’ve been doing it for
millennia; genetic engineering just lets us do it more rapidly. Fuel Production
Some bacteria or archaea (p. 7) can produce methane gas.
Gengineered Microbes
Microbes range from simple bacteria to more complex
These could be used as a renewable energy resource and source
of industrial chemicals. Natural bacteria capable of performing
these activities are in limited use today. At TL8+, gengineered
bacteria capable of much higher performance will be intro-
algae and fungi (such as yeasts and molds). They are living
duced.
chemical factories, taking in specific raw materials and convert-
ing them into the proteins their metabolisms require.
The advantage of gengineering microbes is that their sim- Mining and Refining
plicity and short generation length enable projects to proceed on Bacteria exist whose proteins can bind to and concentrate
a scale of months rather than years. Once microbial products traces of metals from mine shafts, industrial wastes or sea water.
have been developed, industrial biotech processes enable them The biomass can then be collected and refined. More complex
to be cultured in giant fermentation vats that can hold thousands (TL8) versions of these bacteria can excrete the minerals them-
of gallons. With the right nutrients, such a biomass can grow selves, reducing the cost of downstream processing.
very quickly, increasing its total mass eightfold in an hour!
Pollution Control
Microbes at Work
For thousands of years, people have used microbes to man-
Bacteria can be designed to break down plastics that have
been properly treated, while those that metabolize hydrocarbon
molecules can mop up oil spills. Often, bacteria of this sort
ufacture products such as beer, bread and cheese. Beginning in
don’t even have to be genetically engineered. Instead, biotechni-
the mid-19th century (TL5), and continuing into the 20th centu-
cians look for sites that have been contaminated for years by
ry (TL6-7), scientific techniques were applied to the study of
(for example) an oil spill, and then isolate the microorganisms
microbes to find natural strains that performed new tasks or did
that are thriving there. These may also be designed as weapons
old ones better. In this way, microbes usable in improved food
– see Anti-Material Bacteria (p. 90).
and beverage products, industrial chemicals and medicine (see
Antibiotics, p. 92) were produced, most notably penicillin.
Late-20th century (TL7) advances in biotechnology have
largely relied upon gengineering specialized microbes, using the
Terraforming Microorganisms (TL9)
techniques of gene cloning and “protein farming” described in Gengineered algae and bacteria will play a major role in
Chapter 1 (see Gene Cloning, p. 8). With genetic engineering, any planetary engineering program. For example, in a Mars
organisms can produce or extract a wider range of products, terraforming project, they would be released a decade or so
ranging from drugs and fuel to industrial chemicals. after ice asteroid or comet strikes had provided water, but
Fermentation industries, like brewing and the manufacture before organisms are added to the ecosystem. Hardy anaero-
of bread, cheese, yogurt and soy sauce, rely on the action of bic bacteria would perform the critical task of releasing nitro-
microbes such as yeasts, fungi and bacteria. Much of the late- gen locked beneath the planetary surface. Within a decade or
TL7 industrial biotech effort – especially in Japan – has been two, they would be followed up by gengineered lichen and
devoted to the task of finding and mass producing fermentation fungi. In a generation or two (25-50 years), the soil may be
enzymes or genemod microbes to make the process more effi- fertile enough that simple oxygen-producing plants can be
cient or the product more attractive or flavorful introduced.
For microbes to thrive, they need nutrients (such as sugars)
for growth, as well as a carefully-regulated pH (acid) balance.
Some microbes also require a narrow range of temperatures;
because the temperature within a vat can change as the amount
Germ Warfare
Not all microbes are busy little workers. Pathogenic
of biomass increases, most TL7+ fermentation vats possess microorganisms, such as bacteria and viruses, have a long histo-
sophisticated temperature-regulating equipment. As the opti- ry as weapons. Even before people had an inkling of the germ
mum combination of temperature, acidity and nutrients varies theory of disease, medieval siege engines lobbed disease-ridden
from species to species, and the right or wrong choice can carcasses into fortified cities. During the conquest of North
greatly affect yields, experimenting to find the correct vat envi- America, smallpox-laden blankets may have been employed to
ronment is a major element in industrial biotech research. decimate Native American tribes. In the 1930s and 40s, Japan
Engineered Animals
Higher animals – such as fish, dogs or cows – can be bio-
One oft-suggested modification would be
to give the super-efficient ruminant digestive
system found in cows and goats (which uses symbiotic bacteria
engineered, often by adding genes from other species. Just like and a modified intestine to aid digestion) to animals such as
humans, animals can be modified using germline gengineering pigs. This would allow them to forage, which would reduce the
or through a biomod operation. The former has the potential to cost of feeding them.
create a race of modified animals (if a breeding pair is modi-
fied). The latter only modifies a single individual, but can
usually be performed at an earlier TL.
Pharm Animals
So why would someone want to gengineer animals? Some Animals can be turned into living pharmaceutical factories
possible objectives are described below. by adding genes that code for commercially-useful proteins, or
splicing in genes from humans, other animals, bacteria or plants.
Companions and Working Beasts The advantage of using animals rather than bacteria is twofold.
First, more kinds of proteins can be created, since animals have
Pet owners already enjoy exotic breeds. If laws don’t get in more than one cell to work with. Second, animals do not require
the way, we may see dogs with pink fur or strange hybrids like a the fermentation vats and downstream processing that bacteria
cat/rabbit. Even if they are illegal, there may still be a black need.
market for radically-altered pets. While society may frown on Domestic milk animals like goats or cows might be modi-
giving a cat rabbit ears and a semi-intelligent brain for no partic- fied so that their milk contains “natural” additives. This process
ular reason, genemods designed to enhance the intelligence of is underway in 1997. For instance, transgenic cows have been
working beasts like sheepdogs, police dogs or horses may be grown with genes for lactoferrin, a compound used in human
acceptable. At high TLs or in cyberpunk worlds, customized baby formula; this minimizes the need for further processing
“super pets” could be created by finding a freelance genehacker and reduces production expenses. Pigs have already been grown
and having him make a pet to order. with human hemoglobin in their blood so they can be bled for
Some societies may even permit the design of “guard- human blood substitute. Other animals are being designed to
beasts” or “warbeasts” with enhanced combat abilities, derived produce germ vaccines.
ST -4 (-30 points), DX +4 (45 points), IQ -5 (-40 points), The changes made to an ordinary cat were to raise its IQ by
HT +2 (20 points). two (to IQ 7) and add Cast-Iron Stomach, Immunity to Disease
Racial Advantages: Alertness +7 (35 points), Chameleon 2 and Improved G-Tolerance. The only unintended disadvantage
(14 points), Constriction Attack (15 points), DR 1 (3 points), was Stress Atavism. All other advantages and disadvantages are
Enhanced Move (Swimming) 1/2 (5 points), Extra Arms (six, 60 native to cats.
points), Extra Flexibility (10 points), Gills (0 points), Sharp
Teeth (5 points), Smoke (ink: only in water, -30%, 11 points).
Racial Disadvantages: Aquatic (-40 points), Bad Grip (-10
War-Dop (TL10) 32 points
“Navy’s been using conditioned dolphins since the 20th
points), Bad Sight (-10 points), Cold-Blooded (-5 points), Edgy century – and the program’s been continuing, though under
(-5 points), Hidebound (-5 points), Incurious (-5 points), pretty deep cover, mostly out of PR concerns. Some corporate
Innumerate (-5 points), Invertebrate (-20 points), Mute (-25 security outfits are also using them. Recon, mine detection,
points), Presentient (-20 points), Reduced Hit Points -6 (-30 counter-diver missions and counter-terrorist security at oil rigs
points), Short Lifespan 2 (-20 points), Stress Atavism (mild, and such. War-Dop E’s the new generation. The D-model was
uncommon, -6 points). packed full of cyberwear implants, but they were too easy to
The only change made to an ordinary octopus was to raise detect. Aside from some minor brainwork, this model’s blow-
IQ by two (to IQ 5). The only unintended disadvantage was hole’s been modified for human language, and it has a bioelec-
Stress Atavism. All other advantages and disadvantages are tric musculature based on an electric eel with built-in EM field-
native to octopi. sensing capabilities.”
– Captain (ret.) Dana Martello, Marine Force Recon
Space Cat (TL10) -46 points “Last year, Blue Shadow ecowarriors, with some inside
Order: One Felis domesticus, female siamese, with follow- help, raided the dolphin training farm at Pearl and liberated a
ing genemods: augmented intestinal fauna, boosted brain, inter- couple of E-model War-Dops before the conditioning process
nal gravity web, jacked-up immune system. could be completed. Friend of mine in the Movement says one of
Notes on Advantages:
Arms: Many bioships have no arms or legs. Those that
do often seem to have tentacles, with extra hexes of reach
(10 points/yard/arm, p. CI54) and Extra Flexibility (10
points for all arms, p. CI55). If a bioship has more than
two arms, they are Extra Arms (10 points) sometimes with
Modified Arm ST (p. CI61) to reduce ST relative to the
body.
Internal Advantages: Special advantages can also be
bought that apply to the inside of the bioship. A bioship is
normally assumed to have no senses or manipulatory ability
inside it. However, it can buy the following advantages to
No Digital Braintapes
Low and Very Low Resolution Braintapes (TL9) Braintapes can only be stored in a
special MMSD matrix. This means that
These are “quick and dirty” copies of an individual’s mind. A clinical braintape they can’t be copied over and over
machine or portable braintaper can make a “low-res” braintape at +2 to skill for again, or used in ghostcomps, making it
50% of the normal time and cost, or a “very low-res” braintape at +4 to skill for easier to ensure someone “stays dead.”
25% of the normal time and cost. If stored digitally, a low-res braintape takes only
1/2 the storage space; a very low-res one takes only 1/5 the space.
Brain Editor (TL10) Then only one copy of him would wake
up. Perhaps less wastefully, the original
could be kept comatose or in suspended
Brain-editing software allows someone to use a computer to read, delete or alter
animation, in case it is ever needed as a
memories that are stored on a digital braintape. The braintape is not aware of this
backup. This brings up the main disad-
process (as a ghostcomp would be; see p. 122) – only the data on the tape are being vantage of “clone jumping” for those
accessed. who want augmentation: Is the brain-
Using a brain editor is like using the telepathic Mindwipe skill (p. B171), with taped copy really you?
a few exceptions. The user is “in contact” with the braintape once he begins to edit
it, and Psychology or Brain Hacking (p. CI160) skill is used instead of Mindwipe.
The user may search for and “read” specific memories or sets of memories (takes Copy-Protection Nano
one hour per attempt); if trying to remove or change single memories, or specific
areas of memory, he must first locate them. A failed roll does not alert the subject,
(TL10)
Not everyone wants to be copied!
since the braintape is not conscious. However, if any editing (as opposed to simply This technology is used to protect a per-
searching) was done, it will leave traces that the subject will be aware of if the sonality from being copied via braintap-
braintape is actually run – these may be a feeling that something is missing, a mem- ing technology. It “encrypts” the user’s
ory he knows he should recall but can’t, et cetera. memory and personality using decoy
nanomachines, which interfere with
The GM should secretly make all rolls for brain editing. The effects of a brain-
braintaping while not affecting the
editing job will only come to pass if that braintape is actually used (in a clone or user’s brain function in any way. They
ghostcomp). impose a penalty equal to (their TL-5)
To detect brain editing, use the Detecting Mindwipe rules (p. B171) – “the first on any roll to make a braintape of the
time you contact” means the first time you access the braintape. Ignore references user. If no roll for braintaping is
to Telereceive – if the user has reason to believe brain editing has taken place, he normally required, a roll vs. Electronics
can keep looking (roll each hour); if he doesn’t, he gets the initial roll only. Operation (Medical) must be made, with
that penalty.
Whether or not brain-editing technology exists is optional. In fact, if it does, it
A roll that fails by 1 results in a
may be secret; if it is known to exist, people may be very nervous about who they copy that is seriously “defective” – drop
store their braintapes with! A brain editor program is Complexity 6, $20,000. quality by one level: normal becomes
low-res, low-res becomes very low-res
Personality Implants (TL11) and very low-res tapes are completely
useless. A failure by 2 or more means a
These devices are cybernetic implants that allow a braintape to take over a per- fatally flawed copy was made; if pro-
son’s mind. They are described on p. UT110. grammed into in a clone or ghostcomp,
the result will be mindless. There is no
Personality Overwrite Machine (TL11) way to tell whether the copy failed or
not without actually using it in the clone
This is a refined form of mental-programming machine, developed from a or ghostcomp; the GM rolls secretly.
braintape programmer. It allows someone to “overlay” a personality on top of an If soul collectors exist, the GM
existing mind. The result is similar to the personality implants described in GURPS should decide whether or not they can
be jammed; if so, roll 3d vs. the nano’s
Cyberpunk and Ultra-Tech, but instead of the new personality being maintained by TL. On a success, the nano prevents the
an implanted (and removable) device, it produces a permanent change, imprinted soul collector from working.
onto the subject’s brain.
Character Types
These archetypes are typical of people intimately involved in biotech and
warn GURPS Cyberpunk GMs to exer-
cise caution and avoid disrupting the
campaign with all kinds of new, cam-
gengineering. paign-destroying technology. On the
other hand, future shock is a major
theme in cyberpunk fiction! Just make
Bioengineer or Gengineer sure it’s part of the story. For instance, a
new biotech company announces a dra-
“Don’t you see? My discovery will change the world!”
matic breakthrough, things begin leak-
A scientist or engineer working in a field such as gengineering or industrial ing onto the streets, and other corpora-
biotech. Some bioengineers are employed by corporations, while others work in tions follow suit. Massive economic
university labs or even as freelance “genehackers.” A bioengineer may be anything disruption results, with protests in the
from a simple lab technician to a Nobel-prize winning researcher. street, fanatics burning themselves to
A common genre convention is the idealistic scientist who develops a process to protest the desecration of the human
benefit mankind, only to see it stolen and perverted by a rival or treacherous co-work- genome and all that.
It’s up to the GM to decide how per-
er who is in the pay of a big megacorporation’s bioweapons division. Another is the
vasive biotech really is. It can be new
obsessed genius whose cutting-edge project was so controversial that he was fired
and hard to get, or just as common as
from his job or driven out of the field. Now he lives alone somewhere and continues
cybernetics. A cyberpunk world can
his ground-breaking work in private, often without adequate biohazard safeguards. even be mostly biotech, with chrome
Common Advantages: Academic Status, Contacts, Eidetic Memory, Tenure or and silicon being rare and unusual.
Wealth (if established). For geniuses, Intuition and Versatile, and in cinematic cam- Another interesting way to handle
paigns, Gadgeteer. biotech is to have one organization,
nation or culture specialize in cybernet-
Common Disadvantages: Absent-Mindedness, Obsession, Overweight, Poverty
ics and another in biotech. Bruce
(if grad student), Shyness, Skinny.
Sterling’s Shaper/Mechanist stories
Useful Skills: Biochemistry, Computer Operation, Electronics Operation
(see Bibliography, p. 141) are a good
(Medical), Engineering (Biomedical), Genetics (Genetic Engineering), Psychology, example of this kind of cultural divide.
Research, Xenobiology and possibly other scientific skills. In cinematic campaigns, If the GM wants to keep biotech under
Science! and Weird Science. control, the most advanced biotechnol-
ogy could be limited to an outlaw
Biotech Executive group or culture.
“I’m afraid we cannot permit you to continue that research, doctor. The way
public opinion has swung, such work on human germ cells would be detrimental to
Metazyne’s corporate image.”
Hazmat Specialist
“Seven ebola-infected, genemod alligators escaped into the sewers? Yep,
you called the right people. Have the authorities been informed? Ah, I see.
Well, that’s extra. Don’t worry. We’ve handled these things before. We’ll send
our best team.”
An expert at cleaning up hazardous materials, vat spills and other bio-
chemical disasters. Such experts may work for a fire department, disease-con-
trol center, genetic regulatory agency, police force, military unit or corpora-
tion, or be free-lancers hired to clean up others’ messes. Biohazard specialists
may also be trained to deal with hazards such as killing lab animals infected
with diseases or exotic horrors escaped from a military lab. A hazmat team
may include bioengineers or eco-engineers capable of whipping up special-
ized bacteria or counter-bioweapons to deal with a problem.
Common Advantages: Combat Reflexes, Disease-Resistant, Fearlessness,
Immunity to Disease, Resistant to Poison.
Common Disadvantages: Extremely Hazardous Duty, Nightmares,
Sterile, Terminally Ill.
Useful Skills: Animal Handling, Beam Weapons (Flamer), Biochemistry,
Demolition, Diagnosis, Driving, Electronics Operation (Sensors), Guns
(Flamethrower), Guns (Tangler), NBC Warfare, Net, Physician, Poisons,
Tracking, Traps and possibly other combat skills.
Neo-Luddite
“Storm the lab complex! Destroy the abominations within!”
An activist who opposes some or all types of gengineering on social, ethi-
cal or religious grounds. Neo-Luddites range from peaceful lobbyists or pick-
eters to violent extremists. They may be associated with or recruited from
“left wing” groups, like animal rights activists and eco-guerillas, or from
“right wing” groups, like conservative religious movements. Violent neo-
Luddites may turn to bioterrorism, either to “fight fire with fire” or to attempt
to discredit their foes. The Kung Fu 2100 setting (see GURPS Martial Arts
Adventures) has kung fu neo-Luddites fighting the sinister Clone Masters!
Common Advantages: Ally Group, Charisma, Clerical Investment, Strong
Will, Voice.
128 CHAPTER 6: CHARACTERS AND CORPORATIONS
Common Disadvantages: Fanaticism, Gullibility, Intolerance (genemod peo-
ple), No Sense of Humor, Sense of Duty (humanity), Stubbornness, Technophobia.
Useful Skills: Bard, Brawling, Computer Hacking, Demolition, Ecology, Fast-
Talk, Intimidation, Law, Lockpicking, NBC Warfare, Philosophy, Stealth, Theology,
The Organ Trade
Video Production. Medical transplants can save or
extend lives, replacing lost and dam-
aged organs. Until synthetic or cloned
Organlegger replacements are both available and
cheap (which might not happen until
“19 years old, good heart and lungs, healthy kidneys, no diseases . . . a jogger, late TL8) donated organs, especially
huh? Good choice, Charlie. Problem with snatching street people, they’ve got so hearts, kidneys, livers and lungs, may
many retroviruses and defects, it’s not worth the trouble these days. Now this is be in great demand. See Medical
prime stuff: at least $200,000. Break her up, and burn the brain.” Transplants (p. 65) for details of the
transplant procedure.
Organleggers (a term coined by Larry Niven) kidnap people and break them In most places, organs and other tis-
down for spare parts or – more subtly – loot the organs of sick or dying patients sues can be legally taken from a recent-
during hospital visits. ly-deceased person only if he agreed to
As the populace ages and immunosuppressant drugs improve, the correct types be a donor beforehand (often indicated
of organs sell for huge profits on the black market, to people desperate for trans- by a donor card), or if his relatives
plants. The demand may slacken after bionic or cloned organs become available at make the decision. For personal or reli-
TL8-9, but organleggers can still turn a profit by offering their wares at lower gious reasons, many people are unwill-
prices. At TL9+, a potential market for adult human brains to be enslaved inside ing to make that decision. Others die in
circumstances (old age, disease, major
cyborg spaceships, biocomputers or factories could keep organleggers busy.
trauma) where their organs are damaged
Common Advantages: Alertness, Alternate Identity, Danger Sense, Wealth. or unhealthy. A supply of suitable organ
Common Disadvantages: Callous, Enemy (law enforcement), Greed, Low transplants requires finding people who
Empathy, Solipsist. died in good health. As this is almost a
contradiction in terms, locating organ
Useful Skills: Beam Weapons, Diagnosis, Electronics Operation (Medical),
donors can be difficult.
First Aid, Forgery, Guns, Holdout, Merchant, Physician, Streetwise, Surgery. At present, the number of altruistic
people who die healthy is insufficient to
Senior Citizen meet the demand for new organs. This
will probably get worse as transplants
“Well son, I’m 97, and most of the last 15 years have been spent in hospitals become more common around the
like this one. Now you’re telling me that if I let you pump that million dollars worth world. (It may get a lot worse if cryon-
of nano-gook through my body, there’s an even chance it’ll either make me fifteen ics becomes popular, since if you hope
again or kill me. Gotcha, son. Where’s that consent form?” to be frozen after you die, you may need
those organs later!) While this demand
The desire of elderly people to escape death may be the driving force behind may be mitigated if bionic organs
radical advances in human biotechnology. The aged will actively follow the latest become cheaper and smaller, it may not
life-extension treatments (and vote more money for health care subsidies, if these go away entirely.
exist). The extremely rich can afford to sponsor competing lines of cutting-edge Because of this demand, hospitals
research, ranging from anti-agathic drugs and brain or organ transplants to cryonics, often have to put needy patients on
month- or year-long waiting lists for
nanotechnology and braintaping. When it is a question of trying out these treat-
high-demand tissues, such as the body’s
ments or dying, they may well be the guinea pigs for experimental therapy. vital organs or eyes. The GM can
Sometimes even illegal therapy . . . decide how long a wait is necessary, or
Common Advantages: Allies (younger relatives), Common Sense, Contacts, roll randomly. Before cloning is wide-
spread (reducing the demand), a 1-in-6
Multimillionaire, Reputation, Wealthy.
chance of matching major organs being
Common Disadvantages: Absent-Mindedness, Age, Bad Sight, Disembodied available might be typical, with a fur-
Brain, Enemy (including younger relatives!), Extra Sleep, Hard of Hearing, ther chance rolled each month. After
Hidebound, Obdurate, Poverty (spent it all on health care), Short Attention Span, cloning, artificial organs or bionic
Stubbornness, Terminally Ill, Unattractive, Weak Immune System. replacements become common – a 1-in-
Useful Skills: High levels in former job skills. Research (for diligent study of 6 chance per week is more likely.
cutting-edge health care and life extension plans). Things like fingers or limbs will be in
less demand, and may be available
without a wait in most cases.
Splicer Scarce transplants can also mean a
black or gray market trade in organs and
“Welcome to the Clinic Rouge, monsieur. Our discretion is assured.”
other body parts.
Outlaw medics. Street docs. Genehackers. These “splicers” range from unli-
censed or defrocked physicians to the staff of ultra-tech “black clinics” (see p. 135).
Many are simply out-of-work or struggling students moonlighting for extra cash.
Advantages
Alternate Identity p. B233, p. CI20
At TL8+, an alternate identity will normally include your genetic pattern as well
as finger and retina prints.
130 CHAPTER 6: CHARACTERS AND CORPORATIONS
Unusual Background: Gengineered 5 points
You are the living product of germline gengineering (or other genetic modification).
If the genetic engineering gives you positive attribute modifiers, or racial or super
Universal
advantages that an ordinary human cannot take, then the suggested cost is 5 points.
Exceptions: If genetic modification of this sort is not unusual in a TL8+ society
Donors
(GM’s option), the cost should be 0. If the genetic engineering is simply a special Human genome mapping (p. 14) is
effect explaining why you haves certain attributes, advantages or disadvantages an important component of TL8+ organ
within the human norm (e.g,. Beautiful appearance, Combat Reflexes or Immunity transplants, as it allows the genetic pat-
to Disease), it is also worth no points. terns of donated tissues to be matched
precisely with those of recipients.
Disadvantages In some SF backgrounds, rare geno-
types may be discovered that make
Hereditary Disadvantages excellent “universal donors.” This is
the case in the GURPS Cyberworld set-
In a society that practices genetic selection and gene therapy, certain disadvan- ting (p. CW77). Tissue from a “univer-
tages are probably very rare at TL8 and nonexistent by TL9. sal donor” has no chance of being
These include Bad Sight, Bad Smell, Color Blindness, Dyslexia, Hemophilia, rejected.
Migraine, No Sense of Smell/Taste and Tourette’s Syndrome. In addition, Albinism, The fact that a person is a universal
donor would be known to his doctor and
Dwarfism, Fat and Gigantism are likely to be almost unknown, unless one’s parents
probably his insurance company. This sort
or creator deliberately wanted such a disadvantage. of genetic information is, of course, confi-
A character born into a society like this should justify any such disadvantages dential. On the other hand, genetic records
in his character story. For example, his family might have been poor, or their reli- can be illegally stolen, hacked into or oth-
gion forbade gengineering, or he could have been subjected to some mutagenic or erwise disseminated – and once word gets
nano-tech bioweapon, et cetera. around that a person is a good source of
spare parts, he may be in trouble.
Intolerance p. B34 Possible dangers include being kid-
napped by organleggers (p. 129) or
Intolerance toward gene-altered people may become a common form of racism. fetus farmers (see Fetal Tissue
The reverse is also possible, with gene-altered people being prejudiced against Transplants, below), or being besieged
unmodified humans. by desperate people who want to offer
lots of money in exchange for a lung or
Reputation p. B17 kidney. If cloning exists or is under
development, a lab might also want to
“Mass produced” bioroids or clone families may have to live down reputations take (or steal) tissue samples for
based on what other examples of their type have done, due to a public perception cloning, in order to make “generic”
that they are a puppets to their genes. This is especially likely if they are treated as cloned tissue available to its clients.
products or slaves. For example, if it made the news that a Tiger Lily-series plea- Someone who is a universal donor
sure bioroid killed her owner and ran away, all Tiger Lily models may get a reputa- may have a Secret or, if word gets out, a
tion as “dangerously unstable,” regardless of the events (e.g., that particular bioroid Reputation.
was being abused by her owner, and acted to save her life).
In a society where genetic testing is common, those known or believed to have
a genetic defect may also face prejudice, even if they look perfectly normal. This Fetal Tissue Transplants
differs from Social Stigma, where the stigma must be obvious to anyone (see p. Fetal tissue is extremely adaptable
B27) for it to be worth points. and capable of very rapid growth. As it’s
unlikely to be rejected, it makes useful
Secret p. B238, p. CI78 transplant material. Fetal tissue may be
acquired from legal abortions or miscar-
If a society has laws or prejudices against gengineered people, someone with riages. At TL9+, it can also be vat-
hidden modifications will have a Secret. grown.
At TL8, the demand for fetal tissue
Social Stigma p. B27 may exceed the supply. As a result, ille-
gal means may be used to procure fetus-
People who are visibly gene-altered – especially those who are very exotic,
es, such as enslaving healthy women,
such as anthropomorphic animals – may suffer a Social Stigma in some societies. If impregnating them, then aborting the
gengineered exotics are uncommon and the unaltered majority is prejudiced against fetus – over and over again. See p.
them, they will be classed as second-class citizens or a minority group. If genemods CW77 for a graphic description of this
are illegal, an exotic may be an outlaw. An exotic who is the result of an experiment kind of fetus farming.
is probably valuable property. Even if he’s legally a person rather than an animal or
slave, people will want to study him, protect him, et cetera.
Of course, in a world where gengineering is the rule rather than the exception,
visibly unaltered people may suffer from a Social Stigma!
CHAPTER 6: CHARACTERS AND CORPORATIONS 131
About Our Skills
The following skills are especially relevant to biotechnology:
Commentators
“Aquagrrl” is the alias of amateur
marine biologist/ecologist Cherry Lake. Genetics/TL p. B61
Aquagrrl denies rumors that she was This skill has been revised heavily from its original form.
once a member of the outlawed eco- The capabilities and prerequisites of the Genetics skill (p. B61) vary consider-
warrior group Blue Shadow.
ably with TL. Its prerequisites are Botany at TL3-4, Zoology or Botany at TL5,
Lt. Majid Asad is a biomodified FS-
26 Black Widow 2 driver, serving with
Physiology at TL6, and Biochemistry at TL7+.
Navy squadron VF-17 aboard the space Specialization is required (p. B43), in one of two areas:
cruiser USS George W. Bush. Genetic Engineering: The manipulation and modification of genes. This spe-
Tatiana Belenko is a Special Agent cialization is normally only available at TL7+. All gengineers should know this
with the Genetic Regulatory Agency, skill.
based in Geneva, Switzerland. Heredity: The study of inherited traits and the mapping and sequencing of
Dr. Tse Chang was Senior genomes, as described on p. B61.
Academician of the Transpacific Socialist These specializations default to one another at -2.
Alliance’s Genetic Planning Council. In both cases, the skill must be further specialized to a particular type of
Cody Chase is a detective with the biochemistry; e.g., Genetics (Genetic Engineering, Terrestrial). A separate spe-
Nevada Police Department, where she
cialization must be learned to engineer organisms from alien biospheres, but a
has dealt with a wide variety of genetic
code violations and surgical assault
default at -4 or worse may be allowed if the alien biology is quite similar; e.g.,
cases. terrestrial biochemistry is similar to other biologies that are based on proteins,
Marie Detroit is an aspiring pop- water and nucleic acids. Within the realm of a particular biochemistry, knowl-
singer working as a hostess at the Club edge of a specific species’ genetics is a familiarity (p. B43), not a specializa-
Kitsune in Tokyo, Japan. tion.
Genosibyl is the alias of a well-
known poster to alt.bio.upgrade.samurai.
Professor C. Eric Gideon of the
Antarctic School of Economics is a
Nuclear-Biological-Chemical Warfare/TL p. CI151
Genetic engineers who work with dangerous or contagious microorganisms
genome-preservationist and profession- may have NBC Warfare skill. So will “hazmat” or “disease-control” teams sent to
al gadfly.
clean up biological disasters.
Eden Harrier is an expatriate New
Zealander, the owner/operator of Harrier At TL9+, the “chemical warfare” element of this skill also covers operations in
Exports. His firm has been investigated nanomachine-contaminated environments, and techniques used to avoid or clean up
for biohazard and customs violations in nanomachine contamination.
Asia-Transpacific.
Noriko Hayakawa is an Ishtar-
sequence genetic upgrade who hosts the
popular talk show, Cyberia Beat.
Dr. Sayyid Iqbal is a scientist at
Biotech Euphrates’ Human Genetic
Engineering division. He is a frequent
talk show guest.
Copernicus Jones was born in a
growth tank on the moon, but is now
bumming around the solar system as a
travel writer for the best-selling Lonely
System guidebook series.
Walter Jorgenson was a brilliant
young student in molecular biology,
until he developed a series of delusions
relating to alleged paranormal activity.
Surgery/TL p. B56
At TL7+, a surgeon may optionally specialize in cosmetic surgery (called
Arrested in connection with a burglary
and arson at a Dogstar Genetics, an “bodysculpting” at TL8+) or transplant surgery. (These can also be performed by
Ottawa genetic engineering company, he unspecialized surgeons.)
claimed that the company was a front for
“ETs” and “Men in Black.” Found not
guilty by reason of insanity, he is now
confined in an Ontario mental hospital.
Biotech Jobs
Individuals involved in the biotech field may have one of these jobs. See pp.
Continued on next page . . . B192-194 for instructions on how to use a job table.
Biotech Businesses
Do you want to risk losing that beloved pet? Companion Veterinary Services
conspiracy, surgical assault and kidnap-
ping.
Captain Dana Martello is a former
Marine Force Recon medic, presently
offers a full range of cloning, longevity processing and braintaping facilities. pursuing a career as a defense analyst.
Specialists in dogs, cats, birds, reptiles, ferrets, octopi. (No robopets, please.) Twice decorated for bravery under fire
during the Andes conflict, she is assis-
Various types of businesses may specialize in biotechnology. These can include: tant editor of Jane’s Fighting Bioroids.
Captain Zeke Morrigan is a gengi-
Biotech Corporations neered spacer parahuman, and master of
the free trader Antares.
These include companies (or divisions of larger corporations) that specialize in NB-SEK-0172-BUR84 is a Felicia-
gengineering, protein engineering, biomimetics, genome mapping, genemod drugs, series combat bioroid. She is assigned
tissue engineering and other processes. to the Indian Army’s elite 152nd
Some biocorps are large enough to cover the entire field, but most specialize in Paratroop Regiment, with a rank of cor-
a particular area, such as gengineered crops, industrial bacteria, improved animals, poral.
bioroids, terraforming or adapting alien plants and animals. Biotech corporations Dr. Mara Omokage is the mysterious
may also specialize in developing biomodification procedures for use by hospitals and seemingly ageless founder of
Omokage Labs, and a specialist in exot-
and clinics – if a process isn’t yet available on the street, someone with contacts in a
ic bioweapon design.
corporate lab may be able to arrange for it anyway. Raphael-3000 is a vatbrain computer
Small corporations are often undercapitalized “whiz-kid” operations. These installed in the Sisters of Mercy hospital
develop a single brilliant idea . . . and are then bought out by a bigger company, on Seventh Heaven.
usually to market their new invention – but sometimes to suppress it! A certain
Continued on next page . . .
amount of research may also be contracted out to university labs, in exchange for
grants and funding.
Hospitals
At TL8+, major hospitals may perform elective biomodification procedures,
such as transplants, as well as things like braintaping and cloning. Alternatively,
specialized private hospitals that provide these services may develop.
Most hospitals will only perform LC 5-6 procedures.
134 CHAPTER 6: CHARACTERS AND CORPORATIONS
APPENDIX
EXAMPLE: A bioship that weighs 25,000,000 lbs. could
Biotech Advantages, have pockets with a total capacity of up to 2,500,000 lbs. and
would pay 2 points for every 125,000 lbs. of pocket capacity.
136 APPENDIX
Mitigator Variable
A mitigator is something that cancels the effect of a specific
disadvantage without actually buying it off. This is a limitation
on the disadvantage: The more effective the mitigator, the
greater the limitation, meaning the character receives fewer
points for the disadvantage.
The mitigator is worth . . .
-60% if vulnerable and can be easily stolen, broken or mis-
placed, such as a pair of glasses. This mitigator also includes
drugs or other treatments that must be taken daily.
-65% if a weekly treatment is required.
-70% if a monthly treatment is required.
Drug treatments are assumed to cost about $20-$100 per dose
and be available at pharmacies. Those that cost over $100/dose
and require special prescriptions are +5% less (e.g., -70% would
become -65%). Those costing $1,000+ per dose and only avail-
New Limitations
These new limitations are often applied to advantages or
able from specialized sources like hospitals or experimental drug
programs are +10%. People may carry a supply of drugs with
them, but these can be stolen, lost or turn out to be impure.
disadvantages that are the result of biological engineering. More
limitations can be found on p. CI110-112. EXAMPLE 1: Mr. Duncan has Sadism (Mitigator, -60%, -6
points). As long as he takes a special pill ($20, daily) to adjust
his neurochemistry, he is an upstanding citizen . . but if some-
Cardiac Stress Variable one steals his pills, an enemy substitutes aspirin for them, or he
forgets them on a long trip, society is in deep trouble.
This limitation can be taken on any advantage that is used for
a short period of time and then turned off. While in use, the
EXAMPLE 2: Sharra has eyeglasses. Bad Sight is normally
advantage places undue stress on the character’s heart, and the
-25 points, but her glasses are a -60% limitation: -10 points.
character must make periodic HT rolls (a roll of 14+ always
This is a mitigator built into the GURPS Basic Set. The same
fails). Failure means loss of 1d fatigue; critical failure means a
rules can be used for things like hearing aids.
heart attack due to stress and heightened blood pressure. A heart
attack reduces the victim to HT 0 if still at positive HT. He passes EXAMPLE 3: Jan is Terminally Ill with AIDS, and will die
out and will die in HT/3 minutes – regardless of wounds – unless in a month (-100 points). Fortunately, he is on an experimental
he receives CPR (which requires a First Aid-4 or Physician roll, drug plan that is holding him in remission. The treatments are
and can only be performed by a character trained at TL7+). weekly (-65%) and cost $1,000 per week (+10%) for -55%, so
The value of this limitation depends on how often the HT Jan’s Terminally Ill is now worth -45 points. As long as he stays
rolls are made: with the program, the countdown toward his death will be halted.
Every second: -50%
Every 10 seconds: -40%
Every minute: -30%
Every 10 minutes: -20%
Nuisance Effect:
Every hour: -10% Temporary Disadvantage Variable
This limitation can be added to any advantage that can be
Chemical Trigger Variable switched “off” and “on” at will, and which takes at least one
turn to switch. When the advantage is switched on, one or more
This limitation means that an advantage only functions after
disadvantages are suffered by the user until it is switched off
the character has taken a particular drug. In general, this means
again. This limitation is worth -1% per point the temporary dis-
the character must inject, swallow or inhale a drug to trigger the
advantages are worth, to a maximum of -75%.
advantage. For instance, Matsai Accelerated Reflexes need an
inhaled dose of the Dash IV hormone to trigger them. The cost EXAMPLE: A character has sonar, but can’t talk when
of the trigger determines the value of the limitation: he’s using it because he’s sending out ultrasonic pulses. This is
Under $10 per dose: -10% Sonar Vision (25 points) with Nuisance Effect: Mute (-25%),
$10-99 per dose: -20% for 19 points.
$100-999 per dose: -30%
$1,000+ per dose: -40% The point break due to a Nuisance Effect: Temporary
Multiply the value of the limitation by 1.5 if the chemical Disadvantage limitation cannot exceed 80% of the value of the
trigger is illegal, addictive or otherwise dangerous. original disadvantage.
APPENDIX 137
EXAMPLE: A character has Altered Time Rate 1 (100
points) with Nuisance Effect: Bad Temper (-10%). Since Bad Requires Biochip -5%
Temper is worth -10 points normally, the most it can be worth A tiny biocomputer chip must be implanted into the body to
as a Nuisance Effect is -8 points. Thus, it reduces the cost of make the advantage or disadvantage function. This is a limita-
Altered Time Rate by 8 points (to 92 points) and not by 10 tion because the chip can sometimes be detected (requires a
points (to 90 points), as most -10% limitations would. Diagnosis roll at -10, using a medscanner, diagnosis bed or the
like) and removed (a normal use of Surgery skill) relatively eas-
Only disadvantages that could logically inconvenience the ily, neutralizing the advantage or disadvantage. The biochip
character for the period of time the advantage is normally on may also malfunction if subjected to radiation or the like.
should be permitted. In the case of mental disadvantages (e.g., A biochip might be remotely controlled by someone other
Berserk, Bloodlust, Lecherousness, et cetera), if the character than the subject! If they do not always have the subject’s best
loses control of himself due to a failed Will roll, the associated interests at heart, this would be an +5% enhancement to the
disadvantage will not “turn off” until the GM rules he has value of a disadvantage, not a limitation.
regained his composure.
If the GM agrees, a Nuisance Effect can also temporarily
remove some other advantage instead of bestowing a disadvan-
Requires Low Gravity Variable
This limitation means that an advantage does not function
tage. This would be worth -1% per point the negated advantage
in gravity fields over a certain, maximum strength. It is worth
is worth. The value cannot exceed 80% of the deactivated
-5% for every 0.1 G this maximum is under 1 G, as follows:
advantage’s cost. Only one of the involved advantages can take
maximum 0.9 G is -5%, 0.8 G is -10%, 0.7 G is -15%, 0.6 G is
this limitation – one may not take two advantages, both with
-20%, 0.5 G is -25%, 0.4 G is -30%, 0.3 G is -35%, 0.2 G is -40%,
this limitation, each of which negates the other when used.
0.1 G is -45% and 0 G is -50%.
Off-the-Shelf Looks -50% Requires Low Gravity should be applied to humans gengi-
neered with Clinging (usually maximum 0.6 G), Gliding (usual-
This is a limitation on Appearance; it can be taken on either ly maximum 0.4 G) or Winged Flight (usually maximum 0.2 G).
Beautiful/Handsome or Very Beautiful/Handsome. Your looks It can also be an appropriate limitation for some super or psi
are a variation on a standard type or famous person rather than a powers – like Body of Air, DR, Insubstantiality, Telekinesis or
customized design. You’re as beautiful as ever, but with anyone Teleportation – if a gravity field might disrupt fragile force
from your own culture, you get only half the usual reaction fields.
bonus, because they’ve seen it all before! (“Oh, look! Another
Mr. Universe 2023!”) Scent-Based -20%
Only vs. Pheromones -75% This limitation represents an advantage (usually one that
allows a reaction bonus or “mind control”) that operates using
This limitation is usually taken with Weak Will, represent- specialized airborne chemical cues – perhaps modified
ing someone gengineered to have a strong reaction to human pheromones. It only works within 2 yards of someone, and only
pheromones; see Restored Vomeronasal Organ (p. 37). if they have a sense of smell and neither they nor you are using
A variant of this is “Triggered By Pheromones” (-75%), gas masks, sealed suits, et cetera.
which can be taken as a limitation on other behavioral disadvan-
tages. For example, someone exposed to Pheromone Control or
another source of tailored pheromones would suffer another dis-
Sessile -75%
Characters with the Sessile disadvantage (p. CI104) may
advantage (e.g., Cowardice) in addition to the normal effects
buy Extra Hit Points with this similarly-named -75% limitation
(usu. Lecherousness).
to partially compensate for the fact that they are easier targets.
Only With Duplicate -70% Unsupported Strength -25%
This limitation can be taken on advantages or disadvantages
This limitation can be taken on some or all of any ST
that apply only toward a braintaped double (or, less realistically,
increase of +3 or more that’s due to biomods or gengineering. It
with an identical twin or clone). For example, someone may
represents a shoddy job of muscle attachment, or not bothering
have Empathy, Only With Duplicate for 5 points. In some cases,
to take the time to build up bone mass first. This will result in a
this limitation may be worth less – see Multiple People (p. 118)
split ST, with the second, higher (“unsupported”) ST being
for details.
bought with this -25% limitation. Normal ST is used for encum-
Post-Emergencies Only -50% brance, fatigue and most other purposes. However, for any tran-
sitory feat of strength – including lifting, jumping, grappling,
This limitation means that an advantage or, more often, a throwing or attacking – you can choose to use your unsupported
disadvantage, only comes into play after a stressful event like ST. No roll is required to use the strength, but in the following
combat has occurred. The effects will last for about 10 minutes turn, roll vs. HT. Success means no problem occurs, but a fail-
or so (GM’s option). Typically, this limitation is applied to a ure causes 1 point of damage; critical failure, or two failures on
behavioral disadvantage – e.g., “Gluttony (Post-Emergencies consecutive turns, does 1d damage and causes any one limb you
Only)” – to simulate glandular reactions following stress. are using to be crippled.
138 APPENDIX
GL OSSAR Y
This section defines both scientific and fanciful terms found Gene-Cloning: The process of duplicating genes inside mod-
in this book and in biotechnology literature. ified bacteria.
Gene Therapy: Genetic engineering performed on a fetus,
GLOSSARY 139
Prions: Pathogenic proteins linked to various brain diseases Forced-Growth: A way of hyper-accelerating the develop-
such as BSE (“mad cow disease”) and kuru (“laughing sickness”). ment of someone within an artificial womb so that maturation
Prions are also associated with various diseases of aging and senil- from a germ cell to a developed adult takes months, not decades.
ity. Their exact nature remains controversial. It may use massive doses of growth hormones or other methods.
Prokaryotes (“before the nucleus”): Single-celled organisms Genefixed: Used to describe someone whose genes were
with little internal complexity, such as bacteria, whose DNA is not manipulated at conception to fix or screen out genetic defects.
surrounded by a membrane and which lack organelles. Genemod: Short for “genetically modified.” Someone or
Protein: A big molecule made up of long chains of amino something that has undergone genetic engineering. Also refers to
acids. Proteins are formed by cells as directed by their genes, and a genetic modification.
are the basis for the structure and function of living things. There Genesplice: To perform genetic manipulation.
are countless different kinds of proteins, each with its own spe- Ghostcomp: A computer capable of housing a self-aware
cialized function. braintape.
Protozoan: A single-celled microscopic animal somewhat Growth Tank: An artificial womb.
more complex than a bacterium. Korp or Korporate: Cyberpunk slang for “corporate.”
Recombinant DNA: The basis of genetic engineering, this is Metamorphosis (Nano)Virus: A nanovirus capable of per-
the technology of cutting DNA molecules into discrete pieces and forming radical changes in a living being’s anatomy.
recombining them with other DNA molecules to form new genes. Nanite, Nano and Nanobot: Slang terms for nanomachines.
RNA or Ribonucleic acid: A chemical found inside cells that Nanovirus: A swarm of nanomachines designed to transform
is similar in structure to DNA. Different kinds of RNA exist, such a living organism or perform gengineering tasks.
as messenger RNA, which relays the orders from genes to the Parahuman: A variant human who has undergone species
molecular machinery of cells. Because of its ability to tell a cell modification.
what to do, RNA is a primary tool of gengineers. Polykeratin: A form of artificial tissue that is capable of
Ribosome: Parts of the cell’s molecular machinery, these are changing its shape.
“factories” that create proteins under orders from the genes. Proteus Virus: Another name for a nanovirus.
Tissue Engineering: The design of artificial organic tissue. Sensa-Skin: An ultra-tech form of artificial tissue.
Transgenic: A transgenic organism is one that has genes Species Modification: Genetic modification that inserts new
added to it from outside its original species. genes not native to a species’ original genome.
Virus: A non-cellular biological organism that can reproduce Uplift: The process of modifying animals to improve their
only within a host cell. Viruses consist of RNA or DNA covered intelligence, communications or tool-using capabilities, often with
by protein. RNA viruses are especially useful tools for gengineer- the goal of creating a sentient or near-sentient race. A term coined
ing. by SF author David Brin.
Uploading: Slang term for transferring a mind onto a digital
Science-Fiction Terms braintape, especially when the braintape is self-aware in a ghost-
comp.
Android: A completely synthetic humanoid. An android may
Variant Human: A member of a human variant race.
be biological or robotic in nature. Some androids have non-human
Variant Race: A subspecies that has been adapted from the
features, while others look exactly like people.
original species through genetic engineering. Depending on the
Biomod: A biological modification made to a living person
extent of the gengineering, it may be similar to or very different
for non-medical purposes. At TL7, the only biomods are cosmetic
from the original.
surgery. At TL8+, biomods become the organic equivalent of
cybernetics, giving people many new abilities.
Bio-Nanotech: Nanotechnology that relates to biotech-
nology — for example, a nanovirus.
Bioplastic: A pseudo-organic TL10 material. Not to be
confused with certain kinds of plastic made from organic
materials like starch, which are also called bioplastics.
Bioroid (“biological android”): A variant human (or
humanoid) who was force-grown to maturity in a clone tank.
Braintaping: A means of recording memory and person-
ality, for immediate or later transfer to another body.
Clone Tank: An ultra-tech artificial womb equipped to
force-grow organisms (not necessarily clones) to adulthood.
Corpsicle: A corpse that has undergone cryonic preserva-
tion. A term coined by SF author Larry Niven.
Eugeneering: Genetic engineering for eugenic purposes.
140 GLOSSARY
BIBLIOGRAP HY
There are far too many works of fact and fiction to cover in Weaver, Michael D. Mercedes Nights (St. Martins, 1987).
this brief space – instead, this bibliography concentrates on books
especially useful in inspiring adventures and game settings. The Nonhuman Biotechnologies
categories given below are to make research easier – most books Butler, Octavia. Xenogenesis (Warner, 1987).
will overlap into several topics. Harrison, Harry. West of Eden (Bantam, 1984).
Niven, Larry. World of Ptaavs (Ballantine, 1966).
Fiction
Altered People and Posthuman Societies
Norton, Andre. Judgement on Janus (Ballantine, 1963).
Williams, Walter Jon. Angel Station (Tor, 1989).
Cryonics Many magazines and web pages have articles on biotech and related
Bear, Greg. Heads (Tor, 1990). technologies.
Niven, Larry. A World Out of Time (Ballantine, 1976).
Braintaping, Body Transfer and Uploading Games
Chadwick, Miller, Brown and Smith. 2300 (GDW, 1992).
Egan, Greg. Permutation City (Harpers, 1995).
Farmer, Philip Jose. To Your Scattered Bodies Go (Berkley, 1971). Farshtey, Gordon, Stark and Bambra. Space Gods (West End, 1991).
Lee, Tanith. Don’t Bite the Sun (DAW, 1976). Jones, Stefan. GURPS Uplift (Steve Jackson Games, 1990).
Varley, John. The Ophiuchi Hotline (Ace, 1984). Kidd, Paul. Albedo (Chessex, 1988).
Williams, Walter Jon. Voice of the Whirlwind (Tor, 1987). Laker, Laker, and Pevs. Skyrealms of Jorune (Chessex, 1985).
Zelazny, Roger. Lord of Light (Avon, 1967). Sheeley, Craig. “Exotics,” Chromebook 2 (R. Talsorian Games, 1992).
Pulver, David. “The Medusa Sanction,” GURPS Cyberpunk
Human Cloning Adventures (Steve Jackson Games, 1992).
Cherryh, C.J. Cyteen (Warner, 1988). ———. Ultra-Tech II (Steve Jackson Games, 1997).
———. Serpent’s Reach (DAW, 1980). Winters and McLaughlin. Technocracy: Progenitors (White Wolf, 1993).
Levin, Ira. The Boys from Brazil (Bantam, 1976). Wu, Karl. Shadowtech (FASA, 1992).
BIBLIOGRAPHY 141
INDEX
3D Spatial Sense advantage, 33, 71. Bioblimps, 111. Breath Holding advantage, 44, 68. Containment tube, 22.
Absent-Mindedness disadvantage, 53, 72, Biochemistry skill, 59, 77, 98. Breeding programs, see Eugenics. Cool advantage, 36, 72.
74, 113. Bioconvertor, 106. Bully disadvantage, 53. Copy-protection nano, 121-122.
Absolute Direction advantage, 45-46, 71. Bioelectric, organ, 49-50; Shock advan- Callous disadvantage, 53, 72. Corpsicle, 113-114, 139.
Absolute Timing advantage, 45-46, 71. tage, 49-50. Camazotz-series parahuman, 47. Cosmetic, modifications, 34-35; surgery,
Acceleration Tolerance advantage, 34, 82. Bioengineer, 125. Cannot Learn disadvantage, 53, 72, 76. 61; virus, 78.
Acute, Hearing advantage, 46, 64, 100; Biogadgets, 105-111. Cardiac Stress limitation, 137. Cowardice disadvantage, 53.
Taste and Smell advantage, 46, 100; Bioglue, 12. Cardiovascular modifications, 33-34. Crick, Francis, 6.
Vision advantage, 46, 67. Biohazard safety, 21. Cast Iron Stomach advantage, 35. Crops, drought-resistant, 93-94; market-
Addiction disadvantage, 71. Biological warfare, 87-91. Catfall advantage, 42, 63, 100. friendly, 93.
Advantages, animals, 99-100; biotech, Biological weapons, 88; examples, 88-90; Cell, 5, 139; communion, 85; differentia- Cryocase, 22-23.
136; gengineered, 31-59; see also insects, 95-96; plants, 94. tion, 14, 75; stem, 14; surgeons, 85; Cryonics, 113-115, 139; revival, 114.
advantage name. Biomass, 87, 95. transplants, 75. Cryopreservation unit, 114.
Age and aging, 113. Biomechanoids, 107. Centauroid feature, 42, 101. Cultural Adaptability advantage, 72.
Aggressiveness, 56. Biomedical facilities, 22-23. Chameleon advantage, 50. Curious disadvantage, 53.
Albinism disadvantage, 53-54, 78. Biomimetics, 12-13, 139; products, 16. Characters, 125-134; advantages, 130- Damage Resistance advantage, 108.
Alcohol Tolerance advantage, 39, 68. Biomods, 60-85, 98, 139; acquiring, 130; 131; disadvantages, 1313; skills, 132; Darwin, Charles, 5.
Alertness advantage, 33, 71, 100. dollar cost, 61; organ transplants, 67- types, 125-130. Deadheading, 71-72.
Algae, 87, 94-95. 69; point cost, 130. Charisma advantage, 69, 71-72. Deafness disadvantage, 54.
Aliens, 58. Bioroid, 28, 139; see also Variant Human. Chemical, enhancements, 73-75; trigger, Decreased Life Support advantage, 39, 44,
Alpha-series upgrade, 36. Bioscanner, 10. 137; see also Drugs. 68, 81.
Altered, appearance, 61-62; bulk, 62; Biosculpting, 61. Chemsniffer, 16. Deep learning, 20-21.
height, 63. Biosensors, 12, 16. Chimeras, 26-27, 41; plant, 94. Deep Sleeper advantage, 33, 71, 81.
Altered Sex Ratio feature, 47, 49. Bioship, 106-110; advantages, 108-109; Chloramorphosis, 81. Defects, intended, 51-53; unintended, 51-
Alternate Identity advantage, 132. attributes, 107-108; controlling, 109; Chromosome, 5-6, 10, 139; artificial, 8; 54, 59.
Ambidexterity advantage, 33, 71. design, 107-110; disadvantages, 108- manipulation,25. Delicate Metabolism disadvantage, 27, 53-
Amnesia disadvantage, 72, 118. 109; dollar cost, 110; drones, 109- Chronic Depression disadvantage, 52-53, 54, 59.
Amphibious advantage, 49-50, 81, 100. 110; implants, 110; interiors, 109; 72, 76. Delusions disadvantage, 52.
Anabolic steroids, 73. internal advantages, 108-109; life sup- Chronolocation advantage, 33, 71. Deoxyribonucleic acid (DNA), 6-9, 11,
Angelic wings, 41. port, 109; ST and size, 107; trans- Chronos-series bioroid, 48. 13-15, 139; computers, 13; forensics,
Animals, companions and working beasts, forms, 110; weaponry, 109. Chronowomb, 20, 22. 10; junk, 10-11; mitochondrial, 9;
98; creating, 99-102; examples, 102- Biosubs, 111. Chrysalis machine, 23, 82-83, 114. recombinant, 7-8, 25, 139.
105; high-yield farm, 98; modifying, Biotech, 4-23, 139; advantages, 136; busi- Chummy disadvantage, 100. Dependency disadvantage, 81.
100-102; pantropic, 98; pharm, 26, nesses, 133-134; corporations, 133- Claws and talons, 50, 69, 100. Devolutionary modifications, 41-42.
98-99. 134; cyberpunk and, 125; enhance- Cleanup, 127. Dexterity (DX), 30-31; factors modifying,
Anthrax, 88. ments, 136; executive character type, Clinging advantage, 50-51. 75.
Antibiotics, 92. 126; facilities, 20-23; jobs, 134; limi- Clinical, braintape machine, 117, 119; Digitigrade Posture, 39-40.
Antigens, 17. tations, 137-138. metamorphosis, 82-83. Direct brain programmer, 119.
Appearance, 35, 54, 62, 64, 113. Bioterrorist, 126. Clone, 11, 14-17, 19, 116-119, 121-123; Direct programming, 116-117.
Appendix, 137-138. Biotoxins, 88. cross-sex, 16; identification, 16; mem- Disadvantages, animals, 99-100; gengi-
Aquaform, 41-42. Biotronics, 12. ory upload to, 121; spare parts from, neered, 51-54; hereditary, 132; men-
Aquaskin, 81. Black clinics, 135-136. 17; tank, 20, 139; uniqueness, 15-16; tal, 52-53; physical, 53-54; see also
Aquatic disadvantage, 42, 54, 100, 111. Black Death, 89. see also Cloning. disadvantage name.
Arachnoweave armor, 16. Black market, 131. Cloning, 21, 139; costs and times, 16; Discriminatory, Smell advantage, 45-46,
Archaebacteria (archaea), 7, 12, 139. Blastocyst, 6, 26, 139. embryonic cell, 14, 16; gene, 8-9, 87, 100; Taste advantage, 46.
Archwork, 63. Blindness disadvantage, 54, 67. 92; macrobiological, 14-17; plant, 93; Disease, fighting, 91-92.
Arm blade, 69. Blood cops, 84-85. post-embryonic cell, 15-16; see also Disease-Resistant advantage, 37, 69.
Arms to wings, 41. Blood roses, 94. Clone. Disposable test kit, 19.
Artificial womb, 17-19, 57. Bloodlust disadvantage, 52-53. Clothing, post-human, 127. Distractible disadvantage, 53, 72, 74.
Attentive disadvantage, 53, 100. Bodysculpting, 61-64; clinics, 136. Clueless disadvantage, 72. Disturbing Voice disadvantage, 54, 64.
Attributes, animal, 99; bonus table, 31; Bone, decalcification, 42, 74; marrow Collected advantage, 36, 72. DNA, see Deoxyribonucleic Acid.
modifiers, 30-31, 80; penalties, 31; see upgrades, 76; stimulation, 74. Color Blindness disadvantage, 54, 67, 76. Doesn’t Breathe advantage, 49.
also Dexterity, Health, Intelligence Boosted heart, 67-68. Combat Paralysis disadvantage, 52-53, 72. Doesn’t Eat or Drink advantage, 49, 81.
and Strength. Botulinum, 88. Combat Reflexes advantage, 36, 43, 71, Doesn’t Sleep advantage, 33.
Autotrance advantage, 33. Brachiator advantage, 42, 100. 100. Double-Jointed advantage, 42, 63, 100.
Auxiliary heart, 67. Brain, custom, 117; editor, 121; Hacking, Commentators, about, 132-134. Dreamer disadvantage, 53.
B-cells, 37. 121; modifications, 32-33; pod, 23; Common Sense advantage, 33, 71-72. Dreaming skill, 33.
Bacteria, 11, 87-89, 91-92, 139; anti-mate- tissue graft, 71; transplant, 23, 66. Compartmentalized Mind advantage, 33, Drug Factory advantage, 51, 101-102.
rial, 90-91; industrial, 87. Braincorder, 121. 70. Drugs, 73-74, 101-102.
Bad Grip disadvantage, 100, 101. Brainpeeling, 117. Composed advantage, 36, 72. Dull disadvantage, 72, 74, 100-101.
Bad Sight disadvantage, 54, 67, 76, 113. Braintape machine, portable, 121. Computer programs, braintape, 122; Dwarfism disadvantage, 53-55, 63, 76.
Bad Temper disadvantage, 53, 76. Braintaper, portable, 117-118, 120. genetic replication,12; gengineering, Dyslexia disadvantage, 52-53, 72, 76.
Bases, 6. Braintaping, 116-123, 139; alternative 58, 97; genome database, 22; insect Early Maturation advantage, 36.
Battle jaw, 69. technologies, 117; campaign effects, translation, 96; teaching, 21. Easy Childbirth advantage, 48-49.
Berserk disadvantage, 53, 76. 119-120; death and, 117; equipment, Computer Programming skill, 77, 96. Ebola, 89.
Bibliography, 141. 119-123; fees, 115; game effects, 118- Computers, 97, 122-123; biocomputers, Ecological engineer, 127.
Bio-bomb, 102. 119; low-res, 117-118; realism and, 13; DNA, 13. Ecoteur, 127.
Bio-booster, 67. 116; techniques, 116-118; very low- Confused disadvantage, 47, 53, 72, 74. Edgy disadvantage, 52, 100-101.
Bio-stasis, 115. res, 117-118. Constriction Attack advantage, 41. Eidetic Memory advantage, 33, 71.
142 INDEX
Elastic Skin advantage, 49, 70. Genetic engineering, 5-7, 9-11, 14, 21, Inconvenient Size disadvantage, 100, 108. Metamorphosis, 23, 80; clinical, 82-83;
Electronics Operation skill, (Medical), 26, 28, 139; aliens, 58; at conception, Increased Fecundity feature, 48-49. examples, 81-82; nanovirus, 77, 79-
118-121, 123; (Security), 96. 25-30; bioships, 110; humans, 24-59; Increased Speed advantage, 36, 43, 73. 83, 139; transformation, 80.
Embryo, 6; division, 14. in play, 58; insects, 95-97; macrobio- Incurious disadvantage, 53, 72, 100-101. Methuselah program, 78.
Emotional regulator, 76. logical animals, 98-105; microbes, Indecisive disadvantage, 53, 72, 74. Microbes, 139; designing, 97-98;
Empathy advantage, 71. 87-92; objectives of, 27-28; plants, Influenza, 89. enhanced, 89; gengineered, 87-92;
Endocrine system, 36. 92-95; sex and, 26; table, 59; tech- Infravision advantage, 45-46. new, 90; purchasing, 91; see also
Enhanced Move advantage, 39, 41, 70, niques, 6-11. Injury Tolerance advantage, 63. Bacteria and Virus.
100-101, 111. Genetic testing, 9-11, 21; privacy issues, Innumerate disadvantage, 100. Microinjection, 7.
Enhanced Time Sense advantage, 43, 71, 10-11; procedures, 10. Inoculation, 91. Microsurgery, portable, 23.
78. Genetics, 139; skill, 58-59, 77, 97-98, Insect, agents, 96-97; designing, 97-98; Migraines disadvantage, 47, 54, 76.
Enhancements, 3, 136; see also enhance- 132. director, 96; examples, 97; gengi- Mimicry advantage, 44.
ment name. Gengineer, 125. neered, 95-97. Mindshare advantage, 85.
Enzyme, 6, 9, 92, 139; blockers, 92. Gengineering, see Genetic Engineering. Insulin, 8. Miniature humans, 33-35.
Epilepsy disadvantage, 54, 76. Genome, 14, 22, 139; human, 25-26, 32; Intelligence (IQ), 30-31; animal, 100-101; Mining, 87.
Eros plus, 64. library, 22; mapping, 132. factors modifying, 32, 53, 70-71, 74, Mitigator limitation, 137.
Eros-series bioroid, 37. Genotype, 12. 79. Mitochondria, 8-9, 16, 30.
Erythrocytes, 34, 76. Germline genetic engineering, 8-9, 25-27, Interface Jack advantage, 77. MMSD, 115, 117, 119.
Estrus feature, 48-49. 57, 77, 80, 98, 139. Intolerance disadvantage, 131. Modified limbs, 39-40.
Eugeneering, see Eugenics: germline engi- Germs, see Microbes. Introduction, 3. Mold, 87.
neering. Ghostcomps, 122, 139. Intron, 7, 10-11, 139; messages, 35. Monoclonal antibodies, 17, 32, applica-
Eugenics, 5, 25-30, 139; germline gengi- Gigantism disadvantage, 53-54, 63, 76. Intuition advantage, 33, 71. tions, 17-19.
neering, 25-27, 139; society and, 27; Gilgamesh-series parahuman, 50. Intuitive Mathematician advantage, 33. Morph advantage, 49.
vs. species modification, 32. Gills advantage, 44, 81, 111. Invertebrate disadvantage, 111. Morphological changes, 39-42.
Eukaryotes, 7-10, 139. Glandular modifications, 35-37. Ishtar-series upgrade, 42. Multiple people, 118-119.
Eunuch disadvantage, 53-54. Glossary, 139-140. Jagrilla hound, 102. Muscle, grafts, 61, 63; reinforcement, 72.
Eve, 8-9. Gluttony disadvantage, 52-54, 76. Jenner, Edward, 91. Musculo-skeletal modifications, 42.
Evolution, 28-29. Gregarious disadvantage, 100. Job Table, 133. Musical Ability advantage, 33, 71.
Exocrine glands, 51. Growth tank, 18-19, 22, 139; fees, 20; Jointwork, 63. Mutation, 18.
Extended Fertility feature, 48-49. forced, 19-20, 22, 139; portable, 19; K-10, 103. Mute disadvantage, 53-54, 64, 100-101.
Extended Lifespan advantage, 38. portable forced, 20. Killjoy disadvantage, 70, 72. Mycoprotein, 94-95.
Extra Arms advantage, 39-41, 99, 136. Guardbeasts, 98. Lab mice, 102. Nano-symbiotes, 84-85.
Extra Encumbrance advantage, 42, 81. Gullibility disadvantage, 72. Labs, 21, 57-58; biohazard precautions, Nanofever, 80.
Extra Fatigue advantage, 34, 44, 68, 76. GURPS Cyberworld, 126. 21. Nanomachines, 9-10, 13, 19, 77, 83, 90-
Extra Flexibility advantage, 42, 67, 99. Hair graft, 62. Language Talent advantage, 33, 71. 91, 96, 115, 117, 121, 139; see also
Extra Hit Points advantage, 34, 42, 67, 73- Hard of Hearing disadvantage, 54, 113. Laziness disadvantage, 53. Nanotechnology.
74, 81, 108. Hard to Kill advantage, 34, 67-68. Lecherousness disadvantage, 48, 52-53, Nanotechnology, 113-114, 116, 139; see
Extra Legs advantage, 70, 99, 101. Hayflick limit, 38. 76. also Nanomachines.
Extra Sleep disadvantage, 54, 113. Hazmat specialist, 128-129. Legs to arms, 39-40; to flippers, 39-40. Nanovirus, 8, 11, 26, 77, 80, 139; acceler-
Extreme sexual dimorphism, 62. Health (HT), 30-31; factors modifying; 27, Lepus-series parahuman, 43. ated, 82; growing, 77; see also
Eye upgrade, 67. 53, 68, 73. Less Sleep advantage, 33, 100. Metamorphosis and Proteus Virus.
Fat disadvantage, 53-54, 62, 77. Heavy Worlder, 40. Leukocytes, 37. Nanowarfare, 84.
Fauxflesh, 95. Hellkitchen, 22. Lifebank, 22. Nature vs. nurture, 32-33.
Faz Sense advantage, 46. Helot-series upgrade, 41. Lifespan and self-repair modifications, 38. NBC Warfare skill, 91, 127, 134.
Fearlessness advantage, 36, 72. Hemophilia disadvantage, 54-55, 76. Ligase, 7, 139. Neo-, coon, 103; gorilla, 105; horse, 103;
Features, 55-56; see also feature name. Heredity, 12-13, 28. Light Hangover advantage, 39. vampire bat, 102.
Felicia-series bioroid, 38. Hermaphroditism, 48. Light Menses advantage, 48-49. Neo-Luddite, 128.
Fermentation, 87. Hermaphromorph advantage, 49, 81. Light Sleeper disadvantage, 47, 53-54. NERV, 75.
Fetal tissue, 132. Hibernation, 20, 36, 100. Light Worlder, 44. Nervous system modifications, 43.
Field Sense advantage, 45-46. Hide and armor plates, 50, 100. Lightning advantage, 50. Neural augmentation, 73.
Filter Lungs advantage, 44, 68. Hidebound disadvantage, 53, 72, 74, 100- Lightning Calculator advantage, 33, 71. Neuropreservation, 114.
Fit advantage, 34. 101, 113. Limitations, 3, 137-138; see also limita- Neurosurgery, 23, 70-72.
Flashbacks disadvantage, 118. High-biotech fur, 79. tion name. Neurovirus, 79.
Fleming, Alexander, 92. High-efficiency kidney, 68. Literacy advantage, 71. Nictating Membrane advantage, 50.
Flesh Pockets advantage, 50, 108, 136. High Pain Threshold advantage, 47. Liver and kidney modifications, 38-39. Night Blindness disadvantage, 67.
Fleshbeds, 106. High-Pressure Lungs feature, 44. Liver upgrade, 68. Night Vision advantage, 45-46, 66, 100.
Flexibility advantage, 41, 49, 100. HIV, 7. Living structures, 111; bio-buildings, 106; No Appendix feature, 35.
Flight advantage, 41, 82, 99, 108. Homo superior, 27, 29, 36, 50-51; see also sentient buildings, 111. No Depth Perception disadvantage, 67.
Flowers and lawns, exotic, 94. Master Race and Ubermenschen. Longevity advantage, 34, 37-38, 69, 85. No Fine Manipulators disadvantage, 41,
Flu, 89. Horizontal disadvantage, 41, 100-101. Low Empathy disadvantage, 53, 72. 100-101.
Foodstuffs, biotech, 94-95. Horns, 50. Low Pain Threshold disadvantage, 47, 53- No Hangover advantage, 39.
Forced-growth, see Growth Tank. Hospitals, 134. 54. No Manipulators disadvantage, 41, 100.
Fragile disadvantage, 54, 111. Hotshotting, 71. Low-Pressure Lungs feature, 43-44. No Sense of Humor disadvantage, 72.
Franklin, Rosalind, 6. Human, definition, 25. Low Rejection Threshold advantage, 136. No Sense of Smell/Taste disadvantage, 76.
Freeze tube, 115. Human Genome Project, 14-15. Lucid Dreaming skill, 33. Non-Iconographic disadvantage, 72, 76.
Fuel production, 87. Hybridomas, 17. Lunacy disadvantage, 76. Nootropic drugs, 74.
Fungi, 87. Hyper-lungs, 68. Magic, 43, 50, 71. Nuisance Effect: Temporary Disadvantage
Fur, 50, 79, 100, 136. Hyper-Reflexes advantage, 36, 67. Magnetic Sense advantage, 45-46. limitation, 137-138.
Galton, Francis, 5. Hyper-Strength advantage, 36, 67. Manic-Depressive disadvantage, 52, 76. Nutricrops, 94.
Gamete, 57, 139. Hyperactive advantage, 36. Manipulatory ability, enhanced, 101. Obdurate disadvantage, 72, 100-101, 113.
Garcia, Dr., 111. Illiteracy disadvantage, 72. Manna, 94. Oblivious disadvantage, 72.
Gastrointestinal modifications, 35. Immortality, advantage, 38; technology, Manual Dexterity advantage, 42, 63. Octosap, 104.
Gene, 6, 10, 12, 25-26, 139; cloning, 8-9, 112-123. Master race, 28; see also Homo Superior Oedipus-5, 90.
87, 92, 139; cop, 127; expression, 7, Immune system modifications, 37. and Ubermenschen. Off-the-Shelf Looks limitation, 138.
25; gun, 7; therapy, 7-9, 75-76, 139. Immunity, to Disease advantage, 37, 84- Mathematical Ability advantage, 33, 71. On the Edge disadvantage, 52, 72.
Genefixing, 55-56, 139. 85; to Poison advantage, 37, 39, 85. Megalomania disadvantage, 53. One Arm disadvantage, 54.
Genemod, 139, human, 128. Immunosuppression, 65. Memory integration, 122-123; device, 120. Only vs. Pheromones limitation, 138.
Genericillin, 92. Imperturbable advantage, 36, 72. Memory storage, 115. Only with Duplicate limitation, 138.
Genetic, castes, 28; code, 6; defects, 56; Improved G-Tolerance advantage, 34, 36. Memory tissue, 69; see also Polykeratin. Optical biochips, 13.
differences, 15; diversity, 22, 29; Impulsiveness disadvantage, 53. Mendel, Gregor, 5, 12. Organ trade, 129-130; organlegger char-
reconstruction, 11-12, 21; scanner, In vitro fertilization (IVF), 19, 139. Mental instability, 52, 56. acter type, 129-130.
portable, 10; surgery, 75-84; surgery Inbreeding, 28-29. Metabolic processes, 6; reset, 76-77. Organelles, 7-9, 139.
nanovirus, 78; tattoos, 35. Incompetence disadvantage, 72. Metabolism Control advantage, 36. Orion-series upgrade, 45.
INDEX 143
Overconfidence disadvantage, 53. Quadragraft, 70. Slave Mentality disadvantage, 53, 76. Thrombocytes, 76.
Overspecialization, 28-29. Rabbit fever, 89. Slave species, 28. Tissue engineering, 72-73, 139.
Overweight disadvantage, 53-54, 62, 77. Racial, generation, 29-59; point cost, 56; Sleep-state modifications, 33. Total Klutz disadvantage, 73.
Oxygen Storage advantage, 39, 44. templates, 57, 99-100; see also Sleepy disadvantage, 54, 100. Toughness advantage, 42.
Page references, 3. Variant Human. Slow Eater disadvantage, 100, 111. Tourette’s Syndrome disadvantage, 76.
Pandora-series parahuman, 51. Rapid Healing advantage, 34, 38. Slow Healing disadvantage, 54. Trait, analysis, 9; dominant, 12; linked, 26;
Panimmunity advantage, 84. Rapier Wit advantage, 71. Slow Metabolism disadvantage, 111. paranormal, 29; recessive, 12-13; sex-
Pantropy, 27. Recovery advantage, 34, 82. Smart, bug, 97 mosquito, 97. linked, 13.
Parabolic Hearing advantage, 45-46. Reduced Fatigue disadvantage, 63. Smart cardiovascular net, 81-82. Transformations, 49.
Parahuman, see Variant Human. Reduced Hit Points disadvantage, 54. Smart drugs, 74. Transgenic, 139; features, 34-35; gengi-
Paranoia disadvantage, 52-53, 76. Reduced Move disadvantage, 39, 54, 100- Smoke advantage, 51, 111. neering, 26; life forms, 7.
Paranormal abilities, 43; see also Magic, 101. Social Stigma disadvantage, 29, 131. Transplant, 17, 23, 65-70; brain, 23, 66;
Psionic Powers and Super Powers. Reduced Sleep advantage, 33. Solarskin, 82. cat’s eye, 66; cell, 75; limb-replace-
Paravirus, 77. Refining, 87. Sonar Vision advantage, 45-46, 111. ment, 69-70; medical, 65-66, 129;
Parthenogenesis, 48-49. Reflex boosting, 43. Soul collectors, 122-123. rules, 65; tentacle, 67; xeno-, 66.
Passive Defense advantage, 108. Regeneration advantage, 38, 42, 85. Space Acceleration enhancement, 136. Tularemia, 89.
Pasteur, Louis, 91. Regrowth advantage, 38, 85. Space cat, 104. Ubermenschen, 30-31; see also Homo
Penicillin, 87, 92. Rejection, 17, 65, 131, 136. Spacer modification, 46. Superior and Master Race.
Perfect Balance advantage, 45-46, 100. Reproduction, 6. Spartan-series bioroid, 52. Ultrahearing advantage, 45-46, 100.
Perfume glands, 68. Reproductive, Control advantage, 48-49, Species modification, 26, 31. Unaging advantage, 38.
Peripheral Vision advantage, 46. 81; modifications, 99; technology, 17- Spines, 50. Unattractiveness, 56.
Persona mapping, 72. 20. Spleen augmentation, 69. Undulipodia, 8.
Persona-napping, 118. Reputation disadvantage, 131. Splicer, 129-130. Undying advantage, 38.
Personality, implants, 121; overwrite Requires Biochip limitation, 138. Split Personality disadvantage, 53, 118. Unfazeable advantage, 36, 72.
machine, 121-122. Requires Low Gravity limitation, 138. Staid disadvantage, 72, 74, 100-101. Universal Digestion advantage, 35.
Peter Pan process, 74. Residential trees, 94. Sterile disadvantage, 27, 53-54, 59, 62-63, Universal donors, 132.
Pharm, animal modifications, 101-102; Resistant to Poison advantage, 37, 39, 68. 78. Unnatural Feature disadvantage, 54, 62,
animals, 26, 98-99; goat, 102; plants, Respiratory, alternatives, 44; modifica- Steroids, 73, 75. 64, 66-67, 71, 78, 81.
93. tions, 43-44. Strength (ST), 30-31; factors modifying, Unsupported Strength limitation, 138.
Phenotype, 12. Restriction enzymes, 7. 42, 63, 72-75; non-human, 31; unsup- Unusual Background advantage, 131.
Pheromone, 138; Control advantage, 37, Retrovirus, 7-9, 11, 26; see also Virus. ported, 138. Unusual Biochemistry disadvantage, 27,
69; dominance, 37; modifications, 37; Revised pain thresholds, 47. Stress Atavism disadvantage, 52-53, 59, 53-54, 59.
sex, 37. Ribonucleic acid, 6-8, 139; messenger, 6; 101. Uplift, 99, 139.
Pious advantage, 71. virus, 75. Strikers, 40, 50, 66, 100. Uploading, 139; see also Ghostcomps.
Pitiable advantage, 35. Ribosome, 6, 11, 139. Strong Will advantage, 71-72. Ursamorph, 105.
Plague, 95; bubonic, 89; designer, 90; RNA, see Ribonucleic Acid. Stubbornness disadvantage, 53. Used body parts, 65.
pneumonic, 89; see also Biological Sanitized Metabolism advantage, 35. Stuttering disadvantage, 52-53, 101. Vaccines, 91-92; gengineered, 92.
Warfare and Biological Weapons. Scales, 50, 100. Sub-races, 29. Vacuum, Adaptation advantage, 49;
Plants, cloning, 93; designing, 97-98; dis- Scent-Based limitation, 138. Subjugation disadvantage, 108. Support advantage, 49, 82, 108.
ease-resistant, 93; gengineered, 92- Scorpion tail, 40. Subsonic Hearing advantage, 45-46. Variant human, 31-33, 139; custom, 57;
95; growth times, 93; industrial, 93; Secret disadvantage, 131. Super Climbing advantage, 100. designing, 29-59; dollar cost, 57;
modifications, 93; nif, 94; pest-resis- Secret Communication advantage, 85. Super Jump advantage, 42, 100. established, 57; examples, 36-56;
tant, 93; pharm, 93. Selective breeding, see Eugenics. Super-pheromone glands, 69. point cost, 56; templates, 56, 58.
Plasmid, 5, 7, 139. Self-Destruct disadvantage, 53-54, 78. Super powers, 43, 50, 59. Variant racial template, see Variant
Plastid, 8. Selfless disadvantage, 53. Super-steroids, 75. Human.
Polarized Eyes advantage, 45-46. Semi-Upright disadvantage, 100-101. Surge advantage, 49-50. Vat-grown organs, 17.
Pollution control, 87. Senior citizen, 130. Surgery, 61, 80; cosmetic, 61; elective, 61- Venom advantage, 40, 51, 100.
Polykeratin, 69-70, 139; disguise, 70. Sensa-skin, 139; grafts, 70; point cost, 73; hermaphromorphic, 81; skill, 61, Vermiform, 41.
Polymerase chain reaction (PCR), 7, 11, 131. 134. Versatile advantage, 33, 71.
13-14, 139; machine, 13-14. Sensie Talent advantage, 33, 71. Surrogate motherhood, 17-19, 57. Very Fat disadvantage, 62, 77.
Poor Grip disadvantage, 100-101. Sensitive advantage, 71. Suspended animation, 115. Very Fit advantage, 34.
Post-Combat Shakes disadvantage, 52. Sensitive Touch advantage, 46. T-cells, 37. Very Rapid Healing advantage, 34, 38, 76.
Post-Emergencies Only limitation, 138. Sensory modifications, 45-47. Taboo traits, 55-56. Virus, 11, 87-90, 92, 139; biotronic, 77-
Posture, modified, 101. Sentience, 99. Tails, 40; grafts, 66-67. 78; birth-control, 78; cosmetic, 78;
Prefrontal Lobotomy disadvantage, 70. Sessile, disadvantage, 111; limitation, 138. Target-seeking, drugs, 18; pathogens, 89- skin transformation, 78-79; see also
Pregnancy, 18. Sex Appeal skill, 35, 62. 90. Nanovirus.
Prehensile tail, 40; toes, 39-40. Sex change, 61-63; selection, 25. Tech level, 5-6; bioships, 110; experimen- Voice advantage, 44, 64.
Presentient disadvantage, 99-101. Sexual and reproductive modifications, tal procedures, 127; gengineered Voice box, enhanced, 101.
Pressure Support advantage, 44, 111. 47-49. advantages, 32; metamorphosis virus, Void-Dancer-series parahuman, 56.
Programmer, portable, 118, 120. Sexual Orientation feature, 48-49. 80; proteus virus options, 83; varia- Voidshark, 110.
Prokaryotes, 7-8, 11, 139. Shock advantage, 49-50. tions, 6. Vomeronasal organ, 37.
Protein, 6, 139; farming, 87. Short Attention Span disadvantage, 72, 74, Technical terms, 3, 139-140. War-dop, 104.
Proteus nanovirus, 77-79, 84, 139; options, 76, 113. Teeth and fangs, 50, 69, 100. Warbeasts, 98.
82-84; see also Metamorphosis. Short Lifespan disadvantage, 53-54, 100. Tek Rat parahuman, 55. Watson, James, 6.
Psionic, powers, 43, 50, 71, 107; technolo- Shorter Gestation feature, 48-49. Telescopic Vision advantage, 46. Weak Immune System disadvantage, 53-
gy, 122. Shyness disadvantage, 53. Temperature Tolerance advantage, 50-51. 54, 59, 76, 113.
Psychology skill, 121. Single-Minded advantage, 33, 71-72, 100. Terminally Ill disadvantage, 59, 76, 113. Weak Will disadvantage, 37, 53, 72.
Psychosurgery, 71-72. Skeletal strengthening, 81. Terraforming, 87. Webbing advantage, 51.
Quadraform, 41. Skinny disadvantage, 53-54, 62, 77. Testicle tuck, 63-64. Wetware sub-personality, 72.
Whiskers, 46.
Wilkins, Maurice, 6.
Wilmut, Ian, 15.
Winged humans, 40-41.
Workaholic disadvantage, 53.
Xeno-anatomy, 49-50.
Xeno-voice box, 64.
Xenoglands, 50-51.
Xenosculpting, 64.
Xenostriker grafts, 66.
Yeast, 87.
Youth disadvantage, 74.
Zoom womb, 19.
Zygote, 6, 25, 75.
144 INDEX
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