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    Rutin NMR Table

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    Mema Fathy
    1. The document describes the identification of the compound Rutin through analysis of its 1H NMR, 13C NMR, EI-MS, and HMBC spectral data. Key peaks are reported and match references. 2. The spectral data indicates the presence of glucose and rhamnose sugar moieties linked to a rutinaglycone nucleus. 3. The study aims to characterize Rutin, a known antioxidant compound, which was isolated from the leaves of Memecylon edule plant.

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    Rutin NMR Table

    Uploaded by

    Mema Fathy
    64 views4 pages
    1. The document describes the identification of the compound Rutin through analysis of its 1H NMR, 13C NMR, EI-MS, and HMBC spectral data. Key peaks are reported and match references. 2. The spectral data indicates the presence of glucose and rhamnose sugar moieties linked to a rutinaglycone nucleus. 3. The study aims to characterize Rutin, a known antioxidant compound, which was isolated from the leaves of Memecylon edule plant.

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    1. The document describes the identification of the compound Rutin through analysis of its 1H NMR, 13C NMR, EI-MS, and HMBC spectral data. Key peaks are reported and match references. 2. The spectral data indicates the presence of glucose and rhamnose sugar moieties linked to a rutinaglycone nucleus. 3. The study aims to characterize Rutin, a known antioxidant compound, which was isolated from the leaves of Memecylon edule plant.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    64 views4 pages

    Rutin NMR Table

    Uploaded by

    Mema Fathy
    1. The document describes the identification of the compound Rutin through analysis of its 1H NMR, 13C NMR, EI-MS, and HMBC spectral data. Key peaks are reported and match references. 2. The spectral data indicates the presence of glucose and rhamnose sugar moieties linked to a rutinaglycone nucleus. 3. The study aims to characterize Rutin, a known antioxidant compound, which was isolated from the leaves of Memecylon edule plant.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    of 4

    1.

    Rutin:

    Yellow crystals, EI-MS m/z:


    1 H-NMR and 13C NMR (chemical shift δ in ppm) (400 MHz, DMSO)
    Atom C/H δH (ppm) J (Hz) δ(ppm) HMBC δH J (Hz) δ(ppm)
    (ppm)
    Reference [1] [2]
    2 - - 156.88 - - - 156.7
    3 - - 133.73 - - - 134.1
    4 - - 177.81 - - - 178.2
    5 - - 161.66 - 12.602 - 161.5
    6 6.206 d 2 99.17 C-5, C-7, C-8, C-10 6.11 d 2.2 98.9
    7 - - 164.65 - 10.844 - 164.3
    8 6.400 d 1.2 94.07 C-6, C-7, C-9, C-10 6.40 d 2 93.9
    9 - - 157.06 - - - 157.1
    10 - - 104.37 - - - 104.2
    1’ - - 121.61 - - - 121.9
    2’ 7.670 d 1.6 115.69 C-1', C-2', C-3', C-4', 7.55 d 2.1 116.1
    C-2

    3’ - - 145.22 - - - 145.6
    4’ - - 148.89 - - - 148.7
    5’ 6.864 d 8.4 116.70 C-3', C-4', C-6' 6.85 d 8.4 116.5
    6’ 7.568 dd 8.4/2 122.05 C-4', C-6' 7.56 dd 9/2.1 122.0
    β-Glucose
    1” 5.363 d 6.8 101.63 C-1''', C-2''', C-6'' 5.35 d 7.8 101.4
    2” 3.422 m 7/3.3 74.52 - 3.46 m - 74.9
    3” 3.248 m - 76.88 - 3.25 m - 76.7
    4” 3.302 m - 72.28 - 3.29 m - 72.7
    5” 3.373 m - 76.35 - 3.38 m - 76.7
    6” 4.392 m - 67.45 C-4''', C-5''', C-6''' 3.79 m - 67.3
    α-rhamnose
    1” 5.125 d 2.4 101.21 C-1''', C-2''', C-6'' 5.12 d 1.6 101.0
    2” 3.730 m - 70.44 - 3.63 m - 70.8
    3” 3.526 m - 70.82 - 3.53 m - 71.2
    4” 3.276 m - 71.00 - 3.28 m - 71.4
    5” 3.406 m - 68.71 - 3.43 m - 68.5
    6” 1.010 d 6 18.21 C-4''', C-5''', C-6''' 1.13 d 6.2 18.0
    5- OH 12.602 - - C-5, C-6, C-10 - - -
    Ref [3]
    HMBC table

    1. Feng, J.H., et al., Antinociceptive effect of single components isolated from Agrimonia pilosa
    Ledeb. extract. Scientia Pharmaceutica, 2019. 87(3): p. 18.
    2. Srinivasan, R., et al., Antioxidant Compound Quercetin-3-O-α-L-rhamnoside (1→ 6)-β-D-
    glucose (Rutin) isolated from ethyl acetate leaf extracts of Memecylon edule Roxb
    (Melastamataceae). 2015. 5(1): p. 35-42.
    3. Dhiman, A., et al., Development of Rutin Ethosomes for Enhanced Skin Permeation. 2019. 1: p.
    4-10.

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