Article 1

Bernama. ( 2020). Health ministry warns of 9 cosmetic products containing poison. Retrieved,
from https://www.freemalaysiatoday.com/category/nation/2020/07/15/health-ministry-warns-of-
9-cosmetic-products-containing-poison

Health Ministry names night creams banned for containing controlled poisons
PETALING JAYA: The health authorities have banned cosmetic products that have been found
to contain scheduled poisons.

The Health Ministry's National Pharmaceutical Regulatory Agency (NPRA) has warned against
the use of the products as they contain mercury, hydroquinone, tretinoin and/or betamethasone
17-valerate.

Health director-general Datuk Dr Noor Hisham Abdullah said hydroquinone, tretinoin and
betamethasone valerate were controlled drugs.(To be used in main point 1)

"The use of mercury in cosmetic product is strictly forbidden, because it can harm the kidney and
the nervous system ,(To be use in main point 1)" he said, stressing that mercury could also
adversely affect brain development of foetus and young children.

Sifu Kunyit Night Cream contains mercury and betamethasone 17-valerate, while Sifu Kunyit
Day Cream was found to contain hydroquinone, tretinoin and betamethasone 17-Valerate.

Meanwhile, JJ Skincare Glowhite Night Cream contains hydroquinone.

Dr Hisham called upon retailers and wholesalers to immediately stop sales and distribution of the
three banned cosmetic products.

He said first-time offenders who breached the Drugs and Cosmetics Control Regulations 1984
were liable to a maximum three-year jail term and RM25,000 fine.

The penalty would be increased to a maximum five years and RM50,000 fine for habitual
offenders.

Companies would be liable to a maximum fine of RM50,000 for first offence, and up to
RM100,000 fine for subsequent offence.
"Consumers should immediately stop using the products and seek professional healthcare
assistance if they experience any uneasiness or adverse effects," he said.

Hydroquinone could increase risk of skin cancer and causes skin hypersensitivity and
reddishness, apart from blocking the much-needed pigmentation to protect the skin against
dangerous ultraviolet rays.(To be used in maint point 1 )

Tretinoin could also make the skin hypersensitive to sunlight. (To be used in maint point 1)

Betamethasone valerate could cause skin irritation, thinner skin layer, and it could be absorbed
into the bloodstream and adversely affect health. (To be used in maint point 1)

People are advised to surf the NPRA website or download NPRA Product Status from Google
Play Store to check on the status of cosmetic products. (To be use in maint point 2)
Article 2

World Health Organization.(2019). Mercury in Skin Lightening Products. Department of Public

Health,Enviromental and social Determinants of Health. Retrieved, from
https://www.who.int/publications/i/item/WHO-CED-PHE-EPE-19.13

MERCURY IN SKIN LIGHTENING PRODUCTS PREVENTING DISEASE THROUGH

HEALTHY ENVIRONMENTS

Mercury is a common but dangerous ingredient found in skin lightening creams and soaps.
Beauty standards promoted by media, advertising and marketing reinforce the bias that lighter
skin tone is more desirable than darker skin tone. Skin lightening creams and soaps are
commonly used in many African, Asian and Caribbean nations (1, 2). They are also used among
dark-skinned populations in Europe and North America (3–5). Mercury salts inhibit the
formation of melanin, resulting in a lighter skin tone (6, 7). The Minamata Convention on
Mercury establishes a limit of 1 mg/kg (1 ppm) for skin lightening products (8), yet many
cosmetic products contain mercury levels higher than that amount to increase whitening effect
(9, 10). Despite having been banned in many countries, mercury-containing products are often
easily obtainable (11). Mercury can be eliminated from skin lightening products by working with
health and environmental ministries and raising public awareness about the dangers to health
from mercury and other hazardous chemicals in skin lightening products. To stop the
manufacture, import and export of skin lightening products in line with the Minamata
Convention, regulatory actions by governments are needed – including training of customs
agents – as well as major media and advocacy campaigns.

Use, production and availability

• Skin lightening products are used worldwide, but their use is particularly widespread in many
African, Asian and Caribbean countries (1, 12). Skin lightening products are used by both
women and men (13).

• The skin lightening industry is one of the fastest growing beauty industries worldwide and is
estimated to be worth US$ 31.2 billion by 2024 (14). In India, for example, the skin lightening
industry (including products with and without mercury) represents 50% of the skincare market
and is estimated to be worth US$ 450–535 million (14)

.• Mercury-containing skin lightening products are manufactured in many countries and areas,
including Bangladesh (15), China (16, 17), Dominican Republic (18), Hong Kong SAR
(China) (15), Jamaica (15), Lebanon (19), Malaysia (15), Mexico (17, 20), Pakistan (21),
Philippines (22), Republic of Korea (15), Thailand (23, 24), and the United States of America
(25).

• Mercury-containing skin lightening products are available for sale over the Internet, promoted
online on social media sites, and sold through mobile apps. According to the United States Food
and Drug Administration (FDA), these products are often manufactured abroad and sold illegally
in the United States, often in small shops and informal markets catering to Latino, Asian, African
or Middle Eastern communities. Consumers also purchase them in other countries and bring
them back to their country (26). The toxic trade of often illegal mercury-added skin lightening
products is a global crisis expected to only worsen with skyrocketing demand, especially in
Africa, Asia and the Middle East (15)

• A 2011 survey funded by the German Federal Ministry for the Environment, Nature
Conservation and Nuclear Safety noted that individuals from Brazil, Kyrgyzstan, Mexico and the
Russian Federation believe that mercury-containing skin lightening products are easy to obtain
(11).

• A study conducted by the Zero Mercury Group in 2017 and 2018 collected 338 samples of skin
lightening creams from 22 countries in both formal and informal markets to identify a “snapshot”
of the frequency and concentrations where mercury is used as an active ingredient in skin
lightening creams worldwide. Thirty-four creams (10% of the samples) were found to have high
mercury levels, i.e. above 1 ppm. These high mercury samples were found in seven of the 22
countries. Of these seven countries, four had requirements prohibiting more than 1 ppm mercury
content. Overall, the mercury concentrations in these particular products ranged from 93 ppm to
over 16 000 ppm (15). Other studies have found even higher concentrations of mercury in skin
lightening products (27).

• Since 2010, the California Department of Public Health’s Environmental Health Investigations
Branch (EHIB) has conducted investigations of poisonings involving mercury in blemish and
spot-removing face cream products. They have found a variety of mercury-containing products
from Cambodia, China, Japan, Mexico, Pakistan and the Philippines. The EHIB determined that
some of the products caused serious health problems, including health problems that required
hospitalization (28)

.• Many countries have enacted legislation banning mercury-containing cosmetics, but many
others have not. Despite legislation prohibiting mercurycontaining products, their availability
remains a problem (29). Even where distribution is banned, mercury-containing products are
often still easily obtainable (11).• Skin lightening products that do not contain mercury may
contain other hazardous substances, such as hydroquinone. In places where skin lightening
products are used, consumers may be unaware of the harmful effects of the chemicals in these
products (30).

Products, packaging and ingredients

• Skin lightening products come in different forms, including creams and soaps. The soap may be
sold as “antiseptic soap” (3). These products are supposed to be applied to the skin to dry
overnight (3). Both women and men use the soap to wash their hair, arms, face or entire body
(3). It is reported that some individuals have used these products for decades (1).

• The soaps, which are sold in stores and online, come in bar form and are sold individually in
boxes (4). The creams are generally packaged in tubes or jars (4). The soaps contain
approximately 1–3% mercury iodide and the creams are composed of 1–10% mercury
ammonium (3). Some soap products that have been tested contained mercury at concentrations
up to 31 mg/kg (31 ppm), whereas some cream products have been found to have mercury
concentrations as high as 33 000 mg/kg (33 000 ppm) (27). The Minamata Convention
establishes a limit of 1 mg/kg (1 ppm) for skin lightening products, yet many cosmetic products
contain mercury levels higher than 1 mg/kg (1 ppm) to increase whitening effect (9, 10).

• The amount or concentration of mercury in a product may be labelled on the packaging or

listed in the ingredients list. Names to look for include: mercury, Hg, mercuric iodide, mercury
oxide, mercurous chloride, ethyl mercury, phenyl mercuric salts, ammoniated mercury, amide
chloride of mercury, mercury iodide, or “poison”. Directions to avoid contact with silver, gold,
rubber, aluminium and jewellery may also indicate the presence of mercury (3, 4, 26, 31–33). Of
great concern is that companies selling products containing mercury do not always list it as an
ingredient
Health effects

• Adverse health effects ( To be used in main point 3) of the inorganic mercury contained in skin
lightening creams and soaps include: kidney damage (7), skin rashes, skin discolouration and
scarring, reduction in the skin’s resistance to bacterial and fungal infections (31), anxiety,
depression, psychosis and peripheral neuropathy (3, 31).

• The medical literature reports specific instances of individuals suffering from the
aforementioned health effects following exposure to mercury through skin lightening creams and
soaps. One case report describes a 34-year-old Chinese woman who developed nephrotic
syndrome (To be used in maint point 1), a condition marked by high levels of protein in the urine
. Nephrotic syndrome can be associated with a series of complications that affect an individual’s
health and quality of life. (To be used in maint point 1) The mercury levels in the woman’s blood
and urine returned to normal one month and nine months, respectively, after she stopped using
the skin lightening cream (37). Another case report describes a 54-year-old woman with an onset
of dementia, epilepsy and peripheral polyneuropathy at the age of 49. After six years of daily
skin lightening cream application, exposure was stopped immediately, after which her blood and
urine mercury levels returned to unexposed levels (38).

• One study revealed a large proportion of nephrotic syndrome among African women using
ammoniated mercuric chloride–containing skin lightening creams for periods ranging from one
month to three years. After cessation of mercury-containing skin lightening creams, urine
mercury levels rapidly fell to within the unexposed range. Over three quarters of the women who
stopped using the creams went into remission (7, 39).

• Mercury in soaps, creams and other cosmetic products is eventually discharged into waste
water. The mercury then enters the environment, where it becomes methylated and can enter the
food chain as highly toxic methylmercury in fish (3). Pregnant women who consume fish
containing methylmercury can transfer the mercury to their fetuses, which can result in
neurodevelopmental deficits in the children (3).

• Exposure to inorganic mercury can be quantified through measurements in blood and urine
(34).
Actions needed

• To protect the public from negative health effects of mercury in skin lightening products,
actions are needed that engage different parts of society, such as, but not limited to:

-Establishing or improving legislation

- implementing compliance and enforcement strategies for legislation, including training for
customs agents and identification of manufacturers and supply chains;

strengthening laboratory capacity to test for mercury in skin lightening products;

- conducting advocacy campaigns run by national health authorities, and public awareness
campaigns to inform consumers about the health risks of skin lightening products, including
those containing mercury (Conclusion)
- increasing awareness among health professionals of health risks associated with skin
lightening products, including those containing mercury, to inform and educate patients and
the community.
- Conclusions
- • Mercury-containing skin lightening products are hazardous to health and as a result have
been banned in many countries. Even in some countries where such products have been
banned, they are still advertised and available to consumers via the Internet and other means.
• There is a great need for public awareness given the worldwide increase in the use of
cosmetic products containing mercury. (Conclusion)
- • Information on the hazards of skin lightening products in general must be provided to
consumers as even skin lightening products that do not contain mercury may contain other
hazardous substances, such as hydroquinone.
Article 3
Anyssa GarzaPharmD ,(August 3, 2016 ) US Food and Drug Administration, "Mercury
Poisoning Linked to Skin Products"Image Courtesy of Evgenyatamanenko | Dreamstime)

Check Your Beauty Products for Mercury

The US Food and Drug Administration (FDA) is warning about using beauty products that
contain mercury.

That's because mercury exposure can lead to serious health consequences (To be used in maint
point 3). Read on for more information about the dangers of mercury, how to tell which products
contain it and how to stay safe.

What Are The Dangers of Mercury Exposure?

In the past few years, the FDA has identified many products that contain mercury. In fact, the
FDA has identified cases in which people who were exposed to mercury ended up with mercury
poisoning or a high level of mercury in their bodies. Mercury poisoning can lead to serious
nervous system effects and even death. (To be use in main point 1)

And the dangers do not stop with the user. Dr. Arthur Simone, a senior medical adviser at the
FDA, noted in an FDA communication that families may be affected by mercury-
containing products. A family member may breathe in mercury vapors. He also noted the
possibility of being exposed to mercury by touching a contaminated washcloth or towel.
Although everyone is at risk for mercury toxicity, pregnant women, nursing babies and young
children are particularly vulnerable.

What to Look Out For

Check all products, such as beauty and antiseptic soaps, skin creams and lotions, for mercury.
Pay special attention to products that are labeled as “anti-aging” or “skin-lightening," the FDA
notes.

Check the label and look to see if the product contains mercury. You may find mercury under the
following names: calomel, mercurous chloride , mercuric and mercurio. (To be use in main point
2 and 3)

If you find that a product you use contains mercury, stop using it right away. (To be use in main
point 2)

If you encounter a product without a label, that doesn't necessarily mean it is safe to use. ( To be
use in main point 2) Federal law actually requires labels on any cosmetic or over-the-counter
medication to contain a list of ingredients.
In other words, if the product does not have a label, do not use it. In addition, if the product's
labeling is in another language and does not also contain an English label, do not use it.
According to the FDA, products without English labels may have entered the country through
illegal channels or may have been marketed illegally. 

In fact, Jason Humbert, of the FDA’s Office of Regulatory Affairs, said products that contain
mercury are typically manufactured abroad and sold illegally in the US. These products are
typically found in stores that cater to international communities.

Ways to Protect You and Your Family

Make sure to check all beauty products for mercury. If you find a mercury-containing product,
throw it out immediately and appropriately.

When throwing out mercury-containing products, make sure to put the product in a plastic bag or
leak-proof container. Consult with your local environmental, health or solid waste agency for
more information on how to discard these products.

If you have been exposed to mercury, make sure to wash your hands or other parts of your body
that were exposed very well. Contact your doctor for medical advice. The FDA also recommends
calling your health care professional or the Poison Center at 1-800-222-1222 if you have any
questions. (To be use in maint point 2)
Article 4
Bornea Post Online.(Oct 8, 2019). Face cream sold in Malaysia contains concentrated
mercury – CAP. Retrieved from https://www.theborneopost.com/2019/10/08/face-cream-
sold-in-malaysia-contains-concentrated-mercury-

GEORGE TOWN: The Consumers Association of Penang (CAP) found that whitening creams
widely sold in Malaysia contained up to 44,148 ppm (parts per million) ofmercury.(Introduction)

CAP President Mohideen Abdul Kader today said that nine samples of whitening cream have
been tested for mercury and the highest amount of mercury contained was almost twice as high
as the most amount of mercury detected in facial products since 1983.

He said among the samples tested, some of which were already banned by the Ministry of Health
(MoH), but were still widely available in the market.(Introduction)

“The ban was found to be ineffective as face creams containing mercury can still be found in
cosmetic stores and shopping malls across the country, and that includes the counterfeit creams
of some popular brands (Introduction) he said in a press conference here.

According to him, mercury in skin lightening cosmetics posed significant health risks towards
users as it not only damages the skin, but also the kidneys and the nervous system. (To be use in
main point 1)

Mohideen said that regular application of creams containing mercury could lead to rash, skin
discolouration and blotching

“Mercury poisoning may also cause the teeth to loosen and a blue lining to form on the gums.
The fetus of pregnant women may also be affected since mercury can diffuse through the
placenta. he said. – Bernama
Article 5

Mayuree Kanlayavattanakul, Nattaya Lourith. (2018) Skin hyperpigmentation treatment using

herbs: A review of clinical evidences. Journal of Cosmetic and Laser Therapy 20:2, pages 123-
131.)

Skin-lightening creams are extensively promoted online and in the media. They may contain a
wide variety of active ingredients such as mercury, hydroquinone, and steroids that are highly
toxic, especially after prolonged application. (Introduction) For more than a decade, we found
high mercury content in many products sold on Saudi markets. Some of these products were later
banned by the government. However, the presence of other ingredients has not been documented.
We undertake this study on some of the most popular skin-lightening creams on the market to
test for toxic ingredients such as mercury, titanium dioxide, hydroquinone, and corticosteroids. A
total of 33 different brands were selected for the analysis of titanium (50 samples), hydroquinone
(55 samples), and corticosteroids (56 samples) with the exception of mercury in which only 23
brands (34 samples) were tested. This study showed that 2 of 34 skin-lightening creams had
mercury above the US FDA limit of 1 µg g −1. All products had titanium dioxide at less than 25%
(w/w) of the EU and US FDA safety limits for personal products but 8 products from 7 different
brands contained titanium dioxide above 1%, the permissible limit in cosmetics as color
additives. In this study, we found 8 creams from 7 different brands had hydroquinone above
1.5% (w/w), the newly proposed FDA limit of hydroquinone in OTC skin-lightening drug
products. Among the four tested corticosteroid compounds, the most frequently detected was
cortisone and 18 products from 13 different brands were above 6 µg g −1 (MDL) with a maximum
of up to 0.32% (w/w). Dexamethasone was found in 7 creams from 5 different brands with only
3 above the MDL of 9 µg g−1. Although one might argue that these corticosteroids are of mild or
low potency, and they may be unlikely to have any adverse effects, these products are marketed
as personal-care products on the assumption that they are safe and free of steroids. The overall
results indicate that many of the skin-lightening creams sold in the Saudi market contained one
or more toxic ingredients that in most cases were not listed on the packaging. Many of these
ingredients are harmful and pose health risks if we take into account the frequency of
application, the duration of practice, and area of the body applied, and their use during pregnancy
and/or periods of lactation.