Schizophrenia Guidelines - Guidelines Summary

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Schizophrenia Guidelines
Updated: Jul 26, 2021
Author: Frances R Frankenburg, MD; Chief Editor: Glen L Xiong, MD  more...

GUIDELINES

Guidelines Summary
American Psychiatric Association (APA)
The American Psychiatric Association (APA) released the third edition of its Practice Guideline for
the Treatment of Patients with Schizophrenia in 2020.
[134] Recommendations address treatment
planning, pharmacotherapy, and psychosocial interventions. Some of these recommendations are
listed below. 

Assessment and determination of treatment plan

The APA recommends a thorough initial assessment that includes the following components:

Reason patient is presenting

Patient's goals/preferences for treatment

Psychiatric symptoms

Trauma history

Tobacco/substance use

Psychiatric treatment history

Physical health

Mental status/cognitive assessment

Suicidality

Aggressive behaviors

The APA also recommends an initial psychiatric evaluation and a documented, comprehensive,
and person-centered treatment plan.

Pharmacotherapy

The APA recommends treating schizophrenic patients with antipsychotic medication and
monitoring effectiveness and side effects. If a patient's symptoms improve with antipsychotics, the
APA recommends continuing the same medication. 

The APA recommends that treatment-resistant patients be treated with clozapine. This
recommendation also applies to patients at substantial risk of suicide or suicide attempts as well as
those at substantial risk of aggressive behavior despite other treatments.
The APA recommends that patients with acute dystonia associated with antipsychotic therapy be
treated with an anticholinergic medication. 

Psychosocial interventions

The APA recommends patients with schizophrenia be treated with cognitive-behavioral therapy for
psychosis and receive psychoeducation, supported employment services, social skills training, and
cognitive remediation, among other services.

Medication
 
 

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