Unit 01 - Pharmacognosy - 4th Semester Question Bank

Biochemistry Class test
Q1Which of the following enzymes leads to a glycogen storage disease known as Tarui’s disease?
(a) Glucokinase
(b) Pyruvate Kinase
(c) Phosphofructokinase
(d) Phosphoglucomutase
Q2 . Which of the following enzyme deficiency leads to hemolytic anaemia?
(a) Glucokinase
(b) Pyruvate Kinase
(c) Phosphoglucomutase
(d) Phosphofructokinase
Q3 Which of the following is a tricarboxylic acid?
(a) Acetic acid
(b) Succinic acid
(c) Oxaloacetic acid
(d) Citric acid
Q4 Which of the following hormones decreases blood glucose and increases the uptake of glucose
in various tissues like skeletal muscle, adipose tissues?
(a) Insulin
(b) Cortisol
(a) Glucagon
(d) Epinephrine
Q5 Which of the following hormones is responsible for increasing gluconeogenesis in the liver
during prolonged starvation?
(a) TSH
(b) Insulin
(c) Thyroxine
(d) Glucagon
Q6 Which of the following statement about Phosphofructokinase-2 (PFK-2) is false?
a) PFK-2 is a bifunctional enzyme having a kinase domain, phosphatase domain, and a regulatory
domain
b) Activated protein kinase A phosphorylates PFK-2 and activates phosphatase domain
c) PFK-2 catalyzes the conversion of fructose-6-phosphate to fructose 2-6 bisphosphate
d) PFK-2 phosphatase activity is activated by the insulin signaling pathway.
Q7 In absence of oxygen, pyruvate is converted into lactate in muscle because

a) Lactate is the substrate from the downstream pathway
b) Lactate acts as a substrate for the formation of amino acid
c) during the product of lactate two ATP are produced
d) during lactate formation, NADH is reconverted into NAD.
Q8 Which of the following hormone decreases blood glucose and increases the uptake of glucose
in various tissues like skeletal muscle, adipose tissues?
a) Glucagon b) Epinephrinec) Cortisol d) Insulin
Q9 Which of the following statement is true?

a) Glycolysis occurs only in mammalian cells
b) Glycolysis occurs in mitochondria
c) Glycolysis occurs in the presence and absence of oxygen
d) Glycolysis occurs when ATP concentration is high.
Q10 The net gain of ATP during the conversion of glucose to pyruvate is:
a) 1 ATP b) 2 ATP c) 1 ATP +1 GTP d) 4 ATP
Q11 Glycolysis consists of three irreversible steps. Which of the following enzyme-catalyzed
reaction are not irreversible steps in glycolysis?
a) Hexokinase b) Phosphofructokinase
c) Glyceraldehyde-3-phosphate kinase d) Pyruvate kinase
Q12 During prolong starvation, which of the following hormone is responsible for increasing
gluconeogenesis in the liver
a) Insulin b) Glucagon c) TSH d) Thyroxine
Q13 Which of the following statements is known as the rate-limiting step in glycolysis?
(a) Enolase
(b) Phosphofructokinase
(c) Phosphohexose isomerase
(d) Glyceraldehyde-3-phosphate dehydrogenase
Q14 The synthesis of glycogen from glucose is known as:

a) glycogenolysis b) gluconeogenesis
c) glycogenesis d) the Embden-Myerhof pathway
Q15 When a muscle depletes its supply of ATP, the next molecule used as an energy source is:
a) pyruvate b) muscle glycogen
c) blood glucose d) GTP
Q16 Type 1 diabetes mellitus is a disease which is caused by a shortage of:

a) glucagon b) adrenaline
c) glycogen d) insulin
Q17 Liver glycogen can increase blood glucose levels via the process of:
a) glycolysis b) glycogenesis
c) glycogenolysis d) gluconeogenesis
Q18 Which of the following is not true of a type 2 diabetic?

a) They are unable to produce insulin.
b) They lose the ability to import glucose into muscle.
c) They typically face a life of continuing health problems.
d) Their muscles become starved for glucose.
Q19 Which of the following correctly describes conditions in a working muscle cell?
a) oxygen produced, acidity increases, carbon dioxide forms
b) oxygen consumed, acidity increases, carbon dioxide forms
c) oxygen consumed, acidity decreases, carbon dioxide forms
d) oxygen produced, acidity decreases, carbon dioxide consumed
Q20 The final product of carbohydrate catabolism is pyruvic acid.

a) True b) False

Unit 01 - Pharmacognosy - 4th Semester Question Bank

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Unit 01 - Pharmacognosy - 4th Semester Question Bank

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Biochemistry Class test

(b) Pyruvate Kinase

Q2 . Which of the following enzyme deficiency leads to hemolytic anaemia?

(b) Pyruvate Kinase

Q3 Which of the following is a tricarboxylic acid?

(a) Acetic acid

(b) Succinic acid

(c) Oxaloacetic acid

(d) Citric acid

Q6 Which of the following statement about Phosphofructokinase-2 (PFK-2) is false?

b) Activated protein kinase A phosphorylates PFK-2 and activates phosphatase domain

c) PFK-2 catalyzes the conversion of fructose-6-phosphate to fructose 2-6 bisphosphate

d) PFK-2 phosphatase activity is activated by the insulin signaling pathway.

Q7 In absence of oxygen, pyruvate is converted into lactate in muscle because

b) Lactate acts as a substrate for the formation of amino acid

c) during the product of lactate two ATP are produced

d) during lactate formation, NADH is reconverted into NAD.

a) Glucagon b) Epinephrinec) Cortisol d) Insulin

Q9 Which of the following statement is true?

a) 1 ATP b) 2 ATP c) 1 ATP +1 GTP d) 4 ATP

Q14 The synthesis of glycogen from glucose is known as:

Q16 Type 1 diabetes mellitus is a disease which is caused by a shortage of:

Q18 Which of the following is not true of a type 2 diabetic?

Q20 The final product of carbohydrate catabolism is pyruvic acid.

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