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Cefazolin (Drug Study)

Cefazolin is a cephalosporin antibiotic given intravenously or intramuscularly. It works by inhibiting the final step of peptidoglycan synthesis in bacterial cell walls, arresting cell wall assembly and causing bacterial cell death. Cefazolin is indicated for susceptible bacterial infections including sepsis, respiratory, biliary or GU tract, skin and bone infections and surgical prophylaxis. It should be used with caution in patients with a history of immediate hypersensitivity reactions to cephalosporins or penicillins. Adverse effects include diarrhea, nausea, rash and renal or hepatic dysfunction. Nurses should monitor for signs of pseudomembranous colitis or seizures.

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Valerie Villanueva
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7K views1 page

Cefazolin (Drug Study)

Cefazolin is a cephalosporin antibiotic given intravenously or intramuscularly. It works by inhibiting the final step of peptidoglycan synthesis in bacterial cell walls, arresting cell wall assembly and causing bacterial cell death. Cefazolin is indicated for susceptible bacterial infections including sepsis, respiratory, biliary or GU tract, skin and bone infections and surgical prophylaxis. It should be used with caution in patients with a history of immediate hypersensitivity reactions to cephalosporins or penicillins. Adverse effects include diarrhea, nausea, rash and renal or hepatic dysfunction. Nurses should monitor for signs of pseudomembranous colitis or seizures.

Uploaded by

Valerie Villanueva
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOCX, PDF, TXT or read online on Scribd
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Drug Study

Cefazolin
Valerie V. Villanueva BN3-C
Dosage,
Name of Drug Frequency, Mechanism of Action Indication Contraindication Adverse Effect Nursing Responsibility
Route
Generic Name: Dosage: Cefazolin binds to 1 or Susceptible Cefazolin for injection is Diarrhoea, oral candidiasis, Watch for seizures; notify
Cefazolin 500 mg more of the penicillin- bacterial infe contraindicated in vomiting, nausea, stomach physician immediately if
binding proteins (PBPs) ctions includi patients who have a cramps, anorexia; eosinophilia, patient develops or
Brand Name: Frequency: which inhibits the final ng history of itching, drug fever, skin rash, increases seizure activity.
Kefzol Q8H transpeptidation step of septicemia, immediate hypersensitivi Stevens-Johnson syndrome; Monitor signs of
peptidoglycan synthesis in respiratory, ty reactions neutropenia, leucopenia, pseudomembranous colitis,
Classification: Route: bacterial cell wall, thus biliary or GU (e.g., anaphylaxis, thrombocytopenia, including diarrhea,
Cephalosporins IVTT inhibiting biosynthesis and tract, skin serious skin reactions) to thrombocythemia; transient abdominal pain, fever, pus
arresting cell wall and skin cefazolin or the elevation in SGOT, SGPT and or mucus in stools, and
assembly resulting in structure, cephalosporin class of alkaline phosphatase levels; other severe or prolonged
bacterial cell death. bone and antibacterial drugs, hepatitis; increased BUN and GI problems (nausea,
joint, penicillins, or other beta- creatinine levels, renal failure; vomiting, heartburn).
endocarditis. lactams phlebitis, induration; genital and
Surgical anal pruritus (e.g. vulvar pruritus,
prophylaxis. genital moniliasis, vaginitis).

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