Emergency Treatment of Hyperkalaemia: Protect The Heart
Emergency Treatment of Hyperkalaemia: Protect The Heart
OF HYPERKALAEMIA
• Assess using ABCDE approach
• 12-lead ECG and monitor cardiac rhythm if serum potassium (K+) ≥ 6.5 mmol/L
• Exclude pseudohyperkalaemia
• Give empirical treatment for arrhythmia if hyperkalaemia suspected
ECG Changes?
Peaked T waves Broad QRS Bradycardia
Flat/ absent P waves Sine wave VT
NO YES
IV Calcium
10ml 10% Calcium Chloride IV OR
Protect the 30ml 10% Calcium Gluconate IV
heart • Use large IV access and give over 5 min
• Repeat ECG
• Consider further dose after 5 min if ECG changes persist
Insulin–Glucose IV Infusion
Glucose 25g with 10 units soluble insulin over 15 - 30 min IV
(25g = 50ml 50% glucose; 125ml 20% glucose, 250ml 10% glucose)
If pre-treatment BG < 7.0 mmol/L:
Shift K+ Start 10% glucose infusion at 50ml/ hour for 5 hours (25g)
into cells
Risk of
Consider
hypoglycaemia
Salbutamol 10 – 20 mg nebulised
Consider Life-threatening
hyperkalaemia
Monitor K+
and blood Monitor serum K+ and blood glucose
glucose K+ ≥ 6.5 mmol/L
despite medical
therapy