Assignment Lec 4
Assignment Lec 4
BSN-1 NB NSG 10
1. Briefly explain how nervous nerve impulses are initiated and transmitted,
and why one-way conduction at synapses always happens.
Nerve impulse is an electrical charge that travels along the membrane of a
neuron. It can be initiated when a neuron’s membrane potential is changed by
chemical signals from a nearby cell, then it speeds along an axon in milliseconds.
The cell membrane potential changes from negative to positive as sodium ions
flow in (depolarization), and then potassium ions flow out to reset the resting
potential (repolarization).
The place where an axon terminal meets another cell is called a synapse.
This is where the transmission of a nerve impulse to another cell occurs. An action
potential arriving at the presynaptic terminal causes the release of a
neurotransmitter, which diffuses across the synaptic cleft and binds to the
receptors of the postsynaptic membrane. Conduction at synapses is always one
way because only one neuron—the presynaptic cell—has neurotransmitter at each
synapse, while the other—the postsynaptic cell—has the neurotransmitter
receptors that open Na+ ion channels. Therefore, the transmission can never be
in the opposite direction.
The brain is a complex organ, with many parts that perform unique
functions—one of them is the cerebellum. The cerebellum is located at the back of
the brain, underlying the occipital and temporal lobes of the cerebral cortex. Its
main function is to help with the coordination and movement related to motor skills,
especially involving the hands and feet. It helps in maintaining balance, in
coordinating movement, in vision, in motor learning, and even in cognitive
functions. When the cerebellum is damaged, the patient is likely to have
movements that are slow and uncoordinated. Additionally, cerebellar damage also
results to the inability to judge distance, the inability to perform rapid alternating
movements, movement tremors, staggering, wide based walking, tendency toward
falling, weak muscles, slurred speech, and abnormal eye movements. The
physicians might have suspected that the cerebellum is affected because
automobile accidents tend to cause traumatic brain injuries where the brain of the
victim rebounds and hits the skull. This may result to the damage of the cerebellum.
REFERENCES:
Vanputte, C., Regan, J., & Russo, A. (2019). Seeley’s Essentials of Anatomy and
Physiology (10th ed.). Anatomy and Physiology. (Book)