QUESTION BANK

Each question carries one mark

Note: Encircle the alphabet which corresponds to the single best response.

1. One micrometer is equal to:

B. 103 centimeter
A. 10 centimeter
C. 10 meter D. 103 meter
affects the
2. Which of the following properties of a particle significantly
physical, chemical and biological properties of the drug?
A. Density B. Sedimentation
C. Size D. Surface area
3. It is difficult to express the size of particles in a meaningful diameter. The
reason is that the particles in a powder are:
A. irregular in B. irregular surface
shape
C. spherical shapee D. uniform in size
4. The type of a particle diameter obtained largely depends on:
A. method by which it is determined
B. nature of the powder
C. procedure by which it is calculated
D. way it is defined and described
5. When cumulative percent frequency on a probability scale is plotted against
logarithm of the particle size, 50% on the probability scale gives the
powder particle diameter of:
A. arithmetic mean B. arithmetic mode
C. geometric mean D. harmonic mean
6. Which one of these distributions is more important in the design of dosage
forms?
A. Gaussian B. Normal
C. Number D. Weight
7. In the formulation development of emulsions and suspensions, what
diameter is important? type of
A. Length number B. Projected
C. Sieve D. Stokes
 *

8. Sieving method is used for size distribution analysis of powders. The

disadvantage of this method is:
A. agglomerates can be identified
B. attrition of powder is possible
C. large number of sieves are required
D. tedious and time
consuming
9. While using sedimentation method for size analysis, addition of a
deflocculating agent to a suspension is necessary in order to:
A. accelerate the
process of sedimentation
B. make the particles spherical
C. prevent the
aggregation
D. satisfy Reynolds number
10. Stokes' law cannot be used, if Reynolds number is more than:
A. 0.2 B. 1.8
C. 9.0 D. 18.0
11. Andreasen apparatus consists of:
A. balance
B. electrode
C. hydrometer D. pipette
12. When Coulter-counter apparatus is employed for
following criterion is powder analysis, the
important:
A. dispersion medium should be coloured
B. dispersion medium should be conducting
C. suspended particles should be charged
D. suspended particles should be spherical
13. In Coulter-counter, the
as
particles travel through the orifice, the event that
Occurs is:
A. conductance between the electrodes increases
B. electronic scanners produce photographs for volume measurement
C. resistance between the electrodes increases
D. sedimentation increases
14. Fisher subsieve sizer is used to
determine the surface area of the
The surface area is measured based on
the change in:
powder.
A. light
transmission of gas that reaches the detector
B. pressure across the
compacted powder
C. thermal
conductivity of gas across the powdered pack
D. weight of
powder when air is passed through the powdered
15. High repose angle of the granules indicates: pack
A. bulk
density of the granules
B. porosity of the
C.
granules
roughness of the granule
surface
D. smoothness of the granule surface
 density (g/cm°) of talc will
16. The true density of tale is 2.7 g/cm3, the bulk
be:
A. equal to 2.7 B. greater than 2.7
C. less than 2.7 D. unrelated
17. The angle of repose values are utilized to:
A. measure the movement of granules from hopper to the table of tabletting/
capsule machine
B. select proper containers for capsules of a given mass of powders.
C. study the absorption of drugs.
D. understand dissolution of medicament
18. The term light' as applied too pharmaceutical powders means:
A. low bulk density B. low granule density
C. low truedensity D. slightly coloured
19. The type of particle diameter that is obtained by microscope method of
evaluation is:
A. projected B. Stokes'
C. volume D. volume-surface
20. Porosity of porous powder is defined as:
a

A. bulk volume/void volume B. void volume/bulk volume

C. void volume/true volume D. true volume/bulk. volume
6. Micromeritics
1. C 2. D 3. A 4. A 5. C
6. D 7. D 8. B 9. C 10. A
11. D 12. B 13. C 14. D 15. C
16. C 17. A 18. B 19. A 20. B