Prof.

Enderlein’s Research in Today’s View

Can his research results be confirmed with modern techniques?
by Dr. Peter Schneider, Germany

„The best physician in us is love“ formation of all forms of life. His fields of the earth, moon and
Paracelsus works greatly influenced biology galaxy and control both
and geology and even put their protein synthesis and embryo-
The Modern View of Evolution mark on the history of human genesis.
thought.
Questions regarding the origin of This really means that the
life are as old as humankind and However, according to modern evolution of bacteria, plants,
each era tried to find an answer to thinking, evolution rather animals and humans always
this questions with the tools and constitutes the changes in a gene proceeds in a relationship with
means available at the time. Thus, pool over time. A gene is the unit the earth and the overall
evolution theory is also a central of a genetic information which universe. It shouldn’t therefore
topic in modern science, uniting all can be passed on unchanged come as a surprise that a
areas of biology. The modern over many generations. A gene renowned scientist such as Carlos
concept of evolution is basically pool is the sum of all genes in a Bustamente from Berkeley
not hard to understand; but many species or a generation. At the University is searching for “the
scientists still have great difficulties present time the human genome work of God as an intelligent
in integrating this concept is close to being fully decoded. designer” in Coli bacteria.
into their work. This was driven by the expect-
ation that it should finally be Darwin’s concept of evolution
One major mistake, according to possible to detect diseases in a from two centuries ago is, of
Colby, is the continuing assump- population in an early stage and course, totally inadequate as a
tion that the various species to cure them by appropriate model for explaining these
developed upwardly in the form genetic corrections. Newest relationships. In the cultural-
of an “evolutionary ladder”, from results in microbiology and laser anthropological view society at
bacteria through lower and higher microscopy, however, show that that time was in the machine era
animals to, finally, man. Thus, man the DNA and RNA molecules, (1st and 2nd Kondratieff cycle,
is the crown of evolution. This the chemical carriers of the see figure 1) which quite naturally
evolutionary theory basically goes genetic information, are not rigid led to a mechanistic explanation
back to the British student of biochemical structures that can of evolution.
natural sciences, Charles Robert be manipulated easily, but rather
Darwin (1809 - 1882). He laser-active media (Hartmut As the figure shows our society
developed the concept of natural Müller, Raum & Zeit, 109, 2001, right now is in the transition
selection which, in a long lasting page 55). They generate optical from the information age into
process, leads to changes through holograms which are in the 6th Kondratieff cycle. The
adaptation (evolution) and to the resonance with electromagnetic foundation for this event which

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Fig. 1: The long waves of economic activity and its base innovations.
(source: L.A. Nefiodow, The fifth Kondratieff: Strategies for the structural change in
t h e e c o n o m y a n d s o c i e t y. F r a n k f u r t a m M a i n a n d Wi e s b a d e n , 1 9 9 1 )

enhances symbiosis and in- microscopic methods and biophysicists Francis Crick,
cludes all of society, according laboratory procedures for Maurice Wilkins and Rosalind
to Nefiodow, will be the cultivating microorganisms Franklin as well as the American
development of psycho-social there were hardly any other biochemist James Watson which,
and mental potentials - instruments available that would in the early 50’s of the last century,
something immaterial in an have made it possible to do led to the discovery of the general
increasingly material economy. research as we understand it DNA structure, became an
The development of mental- today. However, already at that analysis of the genetic correlations
energetic potentials in the new time, a darkfield microscope was on the molecular level possible.
Kondratieff will decrease standard equipment in any larger
destructive behaviors and, at microbiological laboratory. Even Theory of Endobionts
the same time, increase now, we are still surprised about
productivity in information the relatively simple means with A significant result of Enderlein’s
management and improve which researchers at the time research was the finding that
cooperation, health and well- obtained many pioneering results there is a symbiosis of micro-
being. The modern theory of which only today, with our modern organisms in the human and
evolution therefore agrees laboratory methods, can be animal body which he termed
exactly with this transition. scientifically investigated and “endobionts”. Enderlein was very
understood in detail. From the well aware of the fact that this
Prof. Günther Enderlein surviving research protocols of the designation could be no more
conducted his morphological time we can only imagine the great than a summary term for a variety
studies approximately 100 years intuition and the hard work of very different microorganisms.
ago, in the transition phase to of these researchers. Without mentioning Enderlein as
the 3rd Kondratieff. This was originator the endobiont theory
the era of chemistry and Only after the fundamental has been increasingly confirmed
electrical engineering. Beyond research performed by the British over the last 20 years, among

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others by means of modern it is possible to show the existence genetic material occurs. Whether
molecular biology methods, and of a large number of vastly and to which extent this material
already forms a constant part of different endobiontic guests in the is integrated into the human
the content in many English cells of the human body, in genome always depends on the
textbooks. The modern term addition to the bacterial forms milieu situation of the human host,
coined by Prof. Max Taylor of the already mentioned. These on the infective pressure of the
University of British Columbia, organisms are mostly present as microbes and, in particular, on the
Vancouver, Canada, is “serial “cell wall deficient forms” (CWD) resonance with the above-
endosymbiont theory” (SET). The and are not detected by routine mentioned electromagnetic fields.
genesis of this term and the microbiological methods. Thus,
correlations are described in the about 30% of healthy people were In this context the genetic
recommendable and descriptive found to be carriers of endobiontic modification of microorganisms,
book “Symbiotic Planet - A New types of bacilli in the erythrocytes; a widespread practice today,
Look at Evolution” by Prof. Lynn a recently published study in must be viewed very critically.
Margulis (Perseus Books, 2000). Canada also found evidence of It is performed on an industrial
genetic material from bacteria of scale, e.g. in the food or
The serial endosymbiont theory the pseudomonad type in pharmaceutical industry, to
says that unicellular organisms, erythrocytes of healthy donors imprint new properties onto
plants, fungi, animals and (Richard McLaughlin “Naturally- bacteria. It cannot be excluded
humans are the product of a occurring Pleomorphic Micro- with certainty that the modified
symbiogenesis - this is formation organisms in Human Blood”, genes will be permanently
of new organs and organisms by published in “Pleomorphic integrated into the genome of
symbiotic fusion - of at least two Microbes in Health and Disease”, mammalian cells, with un-
to four life forms. This minimum Holger N.I.S., Inc., 1999). predictable results.
number could be confirmed by
extensive genetic investigations. Already one hundred years ago In addition to the apathogenic,
The nucleocytoplasm, the base Enderlein directly observed endobiontic bacterial forms which
substance of cells, originates CWDs in the darkfield micro- peacefully coexist with the host
from archebacteria, and most of scopy images of blood. According to both partner’s advantage there
the protein-synthesizing meta- to findings of newer micro- is a variety of pathogenic
bolism is derived from thermo- biological research the still microbes that can also be present
acidophilic bacteria. The aerobic common teaching that human as cell wall deficient forms. The
mitochondria formed from blood and tissue are sterile must reason for the formation of such
bacterial symbionts which we be regarded as being outdated. forms is always found in blood
call “purple bacteria” or Symbiogenesis cannot be looked and tissue milieu shifts. Relevant
“proteobacteria” today. And upon as a static, closed event but background information and
finally, chloroplasts and other it still proceeds today in a very therapies are described in detail
plastids from algae and plants dynamic way by continuously in the article “Die tuber-
were once free-living cyano- channeling the DNA and RNA of kulinische Konstitution als
bacteria. Back at around 1950 microorganisms in and out of gemeinsame Ursache chronischer
Hugo Schanderl already body cells. Especially in today’s Erkrankungen und ihre naturhei-
succeeded in retroculturing the age of globalization more and lkundliche Regulationstherapie”
original symbiontic bacteria from more people are in continuous (“The tuberculinic constitution as
mitochondria in the laboratory. contact with new microorganisms common cause of chronic
With modern laboratory methods with which a busy exchange of diseases and their naturopathic

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regulation therapy”) published in (“bacterial cyclogeny”) and the term “cyclogeny” to describe
SANUM-Post No. 51, pp. 4-18. “Akmon”. However, even today, the changes and migration of
it is still very difficult to pathogenic and apathogenic
A comprehensive review of reproduce them on the mol- microorganisms through all
apathogenic and pathogenic ecular level in the laboratory phases (“valencies”), starting
CWDs and their significance is outside the living host organism. below the limit of microscopic
found in the textbook “Cell wall visibility, the realm of viruses,
Deficient Forms -Stealth Starting point for Enderlein’s through the higher-valency phases
Pathogens” by Lida Holmes research was the observation of cocci and rods, up to the
Mattman (CRC Press, 3rd edition, of the French chemist and “culminant” phases of the fungi.
2001). pharmacist Antoine Béchamp in The bacterial nucleus (“mych”) is
the 19th century that, under well of particular significance. Even
Pleomorphisms of Bacteria defined conditions, certain though it was known already
microorganisms can be present in before Enderlein’s time its
Without doubt Enderlein’s different forms and development function was not properly
discovery of the “pleomorphism” stages, from lowest grades up to interpreted. According to the
(polymorphism) of micro- the large, highly developed stages “anatartic fundamental law”
organisms was his most of bacteria and fungi. He found formulated by Enderlein the
controversial for many decades. that all animal and plant cells increase in the microorganisms’
Enderlein coined this term based contained tiny protein grains valency depends on the prevailing
on his then observation that (“microcymas”) which did not milieu in blood and tissue which
bacteria and fungi presented in the perish after the death of the is primarily determined by the pH
darkfield microscope in a variety organism itself and were the value. Bacteria can multiply either
of different forms. Even today reason for the fermentation, and asexually by division or budding
conventional teaching often holds also that other microorganisms (“auxanogeny”) or sexually after
the view of two centuries ago that could develop from them. These a preceding nuclear fusion
microorganisms can only exist in microcymas were thought to be (“probaenogeny”). According to
unchangeable forms. in each living being, in humans, Enderlein sexual propagation is
animals and plants, to be eternal always the prerequisite for phasal
However, conventional clinical- and indestructible and to upward or downward develop-
microbiological research, in constitute the transition between ment.
particular over the last 10 years, non-living and living matter.
realized more and more that the Given some specific or pathogenic More recently Christopher
pleomorphism of microorganisms influence these microcymas could Gerner, assistant at the Tumor
holds some very important develop into bacteria with Research Center Vienna, has tried
aspects with regard to diagnosis putrefacient and fermenting to biochemically characterize this
and therapy of many chronic properties. Thus, the origin of protit. The results of this research
diseases. These studies also diseases would lie primarily were published in “Curriculum
revealed that pleomorphism inside the body. oncologicum” 01 and 03, year 7,
follows certain patterns. Such 1997. As starting material for his
regularities, e.g. the development Enderlein later called these studies Gerner used 10 ml of
cycle of bacteria, have already protein grains “protits”. Starting blood from the vein of a fasting
been described in detail by from such a protit, microbes go, patient. To destroy the erythro-
Enderlein in his major according to Enderlein, through cytes 2 ml of blood were
works “Bakterienzyklogenie” a species-specific cycle. He coined mixed with 4 ml of distilled

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 classified as being identical with endobiontic bacteria gave rise
the protit observed by Enderlein. to the mitochondria of cells a
Then the alleged protits present long time ago. Therefore the
in this material were purified and protits observed in the darkfield
subjected to a thorough bio- image which, by the way, are
chemical analysis. Gerner deter- present in blood in huge
mined globin, a degradation quantities after eating larger
product of the erythrocytes, as amounts of meat, probably
being the main constituent of the represent agglomerations of
alleged protits. This result is not nanobacteria from the mit-
surprising, however, since such ochondria.
degradation products of ery-
throcytes have been known for a The primeval cell was called
long time as so-called “Heinz “mychit” by Enderlein, and it
bodies”. They probably formed contains one nucleus (“mych”).
in the incubation of the The mychit is of spherical form
hemolysate and therefore have with the nucleus being positioned
nothing to do with the protits completely or nearly completely
according to Enderlein, as the against the wall. The following
lowest development phase of darkfield microscopy image
microbes. At least the author did (figure 2) shows an agglo-
not present proof of a dev- meration of such mychits in
elopment of microbes from the
observed “darkfield bodies”.

Fig. 2: “Mychits” in the darkfield Modern microbiological thinking

microscopy image (from Bleker, classifies the structures termed
M.-M.: Blutuntersuchung im protits by Enderlein as prob-
Dunkelfeld nach Prof. Dr. Günther ably being “nanobacteria”.
Enderlein (Blood examination in Nanobacteria were discovered by
the darkfield according to Prof. the Fin Olavi Kajander, University
D r. G ü n t h e r E n d e r l e i n ) , of Kuopio, only about 10 years
2nd edition, Semmelweis, 1997) ago. These organisms which can
grow both inside and outside of
water and thoroughly shaken. mammalian cells show a diameter
The hemolysate was then incubated of 0.2 to 0.3 ìm and are thus as
for 3 days at 37ºC. The residual 8 ml small as viruses; being able to
of blood were left at room withstand temperatures of 90ºC for
temperature. Then the samples were 1 hour, they exhibit a remarkable
centrifuged and 1 ml each of thermostability. They produce
hemolysate and blood serum were biogenic apatite, a major con-
mixed. This mixture was filtered stituent of our bones. Analysis of
sterile and again incubated at 37ºC. their genetic structure points to
Darkfield microscopy then showed them being proteobacteria. As F i g . 3 : Blebs from Borrelia
small grains which the author already mentioned above these burgdorferi (from the internet
site: w w w . l y m e n e t . o r g )
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In 1996 Preac-Mursic et al.
published, in the journal
I n f e c t i o n , a c o r re s p o n d i n g
scanning electron microscope
i m a g e ( f i g u re 4 ) w h i c h W.
Burgdorfer presented as figure 14
in “The Complexity of Vector-
b o r n e S p i ro c h e t e s ( B o r re l i a
spp)” at the “12th International
Conference on Lyme Disease and
Other Spirochetal and Tick-Born
Disorders”, NewYork City, April
9-10, 1999.
blood serum.

According to the new microbiology

nomenclature these structures belong Fig. 4: Mychits from Borrelia burgdorferi in
to the “cell wall deficient bacterial the scanning electron microscope image
forms” (CWD). They have been very
extensively investigated by plasmic membranes very actively problem in borreliosis therapy.
conventional microbiology in the last determine the permeability. Unfortunately these patients are
few years, in particular in the context often accused of simulating the
of chronic borreliosis (Lyme disease). • The outer membrane disease. Conventional wisdom
They can detach from the Borrelia forms a barrier for â- says that an antibiotic therapy
and are then called “bleb” (figure 3). lactam antibiotics. makes little sense in these cases.
Blebs can be of highly variable size • â-lactam antibiotics bind
and were detected for other patho- to p e n i c i l l i n - b i n d i n g By incubating Borrelia in the
genic bacterial forms as well. proteins (PBP) and the â- laboratory with spinal fluid the
lactamases of the outer bacteria mutate within 1-24 hours
Borrelia burgdorferi (Bb) was membrane. to cell wall deficient mychits. By
cultured at 33ºC in the modified • The targets of all other further cultivating the mychits in
Kelly-Pettenkofer culture medium antibiotics are inside the normal medium they revert within
(MKP medium). The image was cyctoplasmic membrane. 9 -17 days back to “normal”
taken 48 hours after addition of Bacteria can develop Borrelia forms (Brorson and
penicillin: two sphere-like bodies are resistance against these Brorson, 1998). Cell wall
attached through a weak connection agents by preventing an deficient Borrelia forms can
to the spiral of a Borrelia organism. agglomeration of the persist in the organism for long
Figure 5 gives arepresentation of substances inside of the periods of time. The cell wall
such a structure. cytoplasmic membrane. dependant antibody titers
disappear with the formation of
The very thin wall (relative to gram- Chronically ill patients, especially mychits, e.g. after antibiotic
positive bacteria) of the CWDs is those with neuroborreliosis therapy. After having reverted
no barrier for the passage of small showing the clinical symptoms back to the normal bacterial forms
molecules such as antibiotics without an increased antibody the corresponding titers reappear
whereas the outer and the cycto- titer in the blood serum, are a big (Mursic et al., Infection 24,

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1996, pp. 218-226). described in SANUM-Post No. Ticks and blood-sucking insects
54, pp. 2-6. are known to be very eager for
SANUM Therapy of Borreliosis the vital energy found in a
At the same time a naturopathic congested meridian.
An important goal of the SANUM therapy of borreliosis must also
therapy of borreliosis is the regulate the energies of the
regulation of the cell wall deficient congested meridians. Very often • for alkalization ALKALA N
Borrelia forms with the haptene a meridian congestion can be Powder daily
preparation SANUKEHL Brucel. recognized by the localization of • 2 x weekly one injection of
The mode of action of the the tick bite and the usually visible NOTAKEHL 5X i.v.
SANUKEHL preparations is erythema migrans that follows. • daily in the evening 8 drops of
SANUKEHL Brucel 6X
(take 4 drops and rub in 4
drops simultaneously)
• in addition once weekly 1
capsule of LATENSIN
alternating with RECARCIN
and UTILIN “S” (start each
with the 6X and move up after
some weeks as required to the
higher strength 4X)

(modified treatment according to

HP Günther Witt)

Enderlein’s view of this relation-

ship

Apart from the now established

pleomorphism of bacteria another
feature of Enderlein’s theory is the
relationship of bacteria to fungi.

According to Enderlein colloids

of the fungi strains Mucor
Fig. 5: Representation of a spirochete with bleb (= mychit); top view (bottom
racemosus Fresen and Aspergillus
left) and cross section (according to Preas Mursic et al., 1996, (“Two spherical niger van Tieghem, which
bodies adhering to the middle of a Borrelia organism”) and Brorson and represent transitions to higher
Brorson, 1998). The surfaces outside the cytoplasmic membrane, that is the forms, have been living in humans
cell wall (ZW = cell wall), and the outer membrane (AM = outer membrane) and in all mammals for millions of
are dissolved by endogenic bacterial lysozymes (dissolving enzymes) during years. They are present in healthy
growth. If, through the use of penicillins or the action of the immune system, organisms in primitive forms
theequilibrium between bacterial dissolution and reconstruction is disturbed, which have an important
cell wall deficient forms develop where the cyctoplasmic membrane (ZM = regulatory function in the met-
cytoplasm membrane) and the flagella become visible from the outside (from abolism.
the internet site:www.lymenet.org).

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For various reasons - infection,
wrong nutrition, unnatural living
environment, mental depression,
age effects etc. - these primitive
forms can change into higher
stages according to Enderlein,
making them parasitic. An
infestation by the parasitary phase
can be detected in blood by dark-
f i e l d m i c r o s c o p y. T h e n t h e
valency of the parasites can be
determined.

In over 40 years of intense research

Enderlein has observed the changes Fig. 6: Hypothetical separation of the cyclode of Aspergillus niger
and development of the parasites in from the cyclode of Mucor racemosus (Arnoul, 1998; Rau, 1998)
their various forms, as well as their Aspergillus phases are relatively organism. This situation explains
cycle. Only after he was in the position rarely seen in a pathogenic stage - the various disease presentations
to present the biological and only in the tuberculous and para- seen in humans and animals.
biogenetic basis of these parasites, tuberculous diseases - the Mucor Figure 6 shows a hypothetical
therapeutic countermeasures could be symbiosis as the proper “endo- representation of the development
developed. This led to the “isopathy” biosis”, in its pathogenic stages, is cycles for these two fungi acc-
concept which said: The various much more often involved in the ording to Enderlein.
higher forms observed are reduced to development of pathologic
lower forms by appropriate med- functions or changes. There is no The development process of the
ication and leave the body warm-blooded organism which has endobiont shows, in its primeval
through the excretory organs. not acquired this “endobiont” stage, initially the most primitive
diaplacentally and harbors at least form: the colloid stage. Colloids
Enderlein’s original microorganism its primitive forms in its cells and are extremely tiny protein
strains and the original formulas for body fluids for life. particles which grow and pass
his medications were acquired through several intermediate
exclusively by SANUM-Kehlbeck According to Enderlein this fungal stages and then can enter into the
company 25 years ago. parasite mutates through all its bacterial stage. After several
development stages in the body and further stages within this
This microorganism which every- can infiltrate tissues and organs to development cycle, stages which
where penetrated into the various degrees. For instance, it can give rise to a wide variety
mammalian cycle millions of years can lead to stasis in the circulating of chronic diseases, the last
ago was called “endobiont” by body fluids which in turn leads to stage of the cycle is the fungus
Enderlein. The presence of dysfunctions in various directions. and this is were the cycle starts
Aspergillus niger van Tieghem and The slightest impairment of a tissue anew. Thus, according to
Mucor racemosus Fresen in the body or an organ leads to an increased Enderlein, the endobiont goes
can be regarded as cause for a valency of the endobiont and through three fund a m e n t a l
number of disorders. Whereas the thereby further weakens the sick development phases: colloid -

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 the, at least partial, correctness
of Enderlein’s theory.

Pathogenic bacteria as regressed

fungi

Fungi are plant-like entities

without chlorophyll. They
therefore cannot photosynthesize
with the aid of sunlight and are
dependant on foreign organic
matter. In the human body, they
are parasites rather than
Fig. 7: Bacterial sex - bacterial exchange of DNA symbionts. Similar to bacteria,
( f r o m t h e I n t e r n e t : h t t p : / / w w w. s l i c 2 . w s u . e d u : 8 2 /
hurlbert/micro101/pages/Chap.9.html) fungi can also be present as cell
wall deficient forms. However,
bacterium - fungus which, up this is mostly an expression of a
t o n o w, w e r e r e g a r d e d a s However, according to Enderlein, highly shifted milieu with a
independent, unchangeable the higher forms can also regress weakened immune defense,
organisms. Prof. Enderlein to lower stages when the so-called such as in Kaposi’s sarcoma.
demonstrated this development chondritins (lower, apathogenic
process and said that all these development stages) in the Some characteristics of fungi are
stages together form a single respective isopathic medications (according to Tom Volks,
common cycle which originates combine with the higher-valency University of Wisconsin-
from the completely identical, forms. The degradation products La Crosse, USA):
unstructured, colloidal and formed in this process must be
motionless protein material excreted by the body. If this • They are eukaryots, i.e. they
contained in the respective cells. excretion does not proceed have cells with a nucleus and
These protein particles of the quantitatively in case of disease an complicated organella such as
primitive stages are in the size upward development can re- mitochondria.
range of bacteriophages and establish itself. • Replication by means of
viruses (approx. 0.01 ìm). Under spores.
certain conditions this mass can Enderlein’s view of the special • Sexual and asexual spores can
release forms that had dev- importance of the two fungi be formed.
eloped in a disease-generating Mucor racemosus and Aspergillus • Fungi show, similar to plants,
environment and continue niger has not yet been heterogenesis.
circulating in the cycle. They sufficiently confirmed by • The vegetative body can be
replicate and form an endless today’s microbiological re- unicellular (yeasts) or be
number of different shapes and s e a r c h . However, some re- present as hyphen.
forms. They increase in size and searcher arrived at similar • The cell wall structure res-
finally develop into bacteria when conclusion as Enderlein did, bases embles that of plants, the
the surrounding milieu changes on their own research. And finally composition, however, differs.
(in humans, for instance, by the very successful therapies with • The fine structure of the
nutrition consisting mostly of isopathic medications according cytoplasm is similar to plants,
animal proteins and fats). to Enderlein strongly support the organellas, however, are

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 different. replication in eukaryots. Gerlach was able to show the
• Fungi use exoenzymes to first regular presence of a micro-
digest their food extracellularly Sexual replication is very unusual organism in all spontaneously
and then ingest it. for bacteria since it occurs only formed, malignant growths in
• New molecular research with higher organisms. According humans and animals, both in the
suggests that fungi are closer to Enderlein it is the base for the primary tumors as well as in the
to animal than to plants. therapeutic success with iso- metastases and in recurrent
pathic-homeopathic SANUM growths.
The properties suggest that many medications prepared from molds.
fungi have originally been plants As emphasized by Dr. Thomas This organism showed a
during the evolution. They lost Rau (Das isopathische Prinzip – remarkable pleomorphism: The
their chlorophyll in the course of Medikamententestung mit Hilfe major mass usually formed small
evolution and adapted to a der Dunkelfeldmikroskopie (The granular forms, in the cycto-
parasitic life style. isopathic principle - testing of plasms of cells as well. In
drugs by means of the darkfield addition there were larger
The majority of pathogenic microscope), SANUM-Post 53, p. spherical entities which we know
bacteria seem to belong to these 9, 2000) the degradation of the call blebs and which sprouted
parasitic fungi as well. Another high-valency fungal forms in from one or several locations
important finding of Enderlein blood after addition of the along the periphery. This
which supports this assumption appropriate isopathic SANUM involved the formation of
was the fact that bacteria can medication can be directly filaments of various lengths
replicate sexually. This mode of observed by examining a freshly which each formed a small
replication is, according to taken blood sample under the sphere at their free ends. In
Enderlein, always a prerequisite darkfield microscope. addition small granules with
for the upward or downward strand-like appendices, free
development of the phases. The studies of Franz Gerlach and filaments, ring shapes, irregular
Hans Harmsen provide further bloated forms and branched
The discovery of sexual confirmation for a core statement mycelia with attached granular
replication of bacteria was taken in Enderlein’s theory that forms were observed. Acc-
up by the Americans Joshua bacteria and fungi are only ording to Gerlach all these forms
Lederberg and Edward Lawrie different representations of a originated from one and the
Tatum, and published in 1946 in specific species. (Gerlach: same parasitic fungus which
the USA. In 1958 Lederberg, “Krebs und obligater Pilz- was termed micromcyete.
together with Tatum and George parasitismus” (“Cancer and
Wells Beadle, was awarded the obligatory fungal parasitism”), When study animal were infected
Nobel prize for medicine “for his Urban & Schwarzenberg, 1948, in various ways with pure cultures
discoveries concerning genetic reprints as 2nd edition published of this fungus, in most cases a
recombination and the organ- at Semmelweis-Verlag, 1998) general disease of the organism
isation of the genetic material of (Harmsen: “Zur Morphologie resulted similar to that found in
bacteria”. During copulation der Erreger der Tuberkulose” the cadavers of carriers of
certain bacteria, e.g. E. coli, (“About the morphology of the spontaneous tumors. Clinically
transfer a small fragment of their germs causing tuberculosis”), the disease was often not
DNA to a receiving bacterium Klinische Wochenschrift 30, detectable and pathologically-
(figure 7). This recombination is 817-819, 1952). anatomically only after thorough
the equivalent of the sexual examination. Most prominent

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 were exudative processes in the Lancet 356, 2133-2137, 2000). development stages contained
large body cavities. Microscopic The tests were performed on in the preparation. According
examination always showed patients who had died from to present knowledge the
tumor mycetes in pure state. The tuberculosis as well as from other copulative inactivation of higher
fungus spreads in the infected diseases. The bacterial DNA development phases by lower
organism by septicemia. Acc- could be detected with genetic phases seems to be the only
ording to Gerlach it can give rise research methods, not only in logical explanation for the fact
to a variety of diseases including macrophages but also in other that lower development forms
bacterial infections in cattle and cells. Interestingly, this DNA was can interact at all with higher
sheep, and it is an obligatory not only found in all patients who forms.
parasite in all malignant had died from tuberculosis but
growths. also in approximately one third of
those patients dead with other First published in the German language in
the SANUM-Post magazine (56/2001)
Harmsen also observed a diseases. However, this included
prominent pleomorphism of the only patients from countries © Copyright 2001, Semmelweis-Institut
• 27318 Hoya • Germany
tubercle bacterium. The acid-fast where tuberculosis is endemic,
rod form of this bacterium, nearly such as Ethiopia and Mexico. In All Rights Reserved

exclusively used for routine patients from Norway which is

diagnostics even today, is just one considered as being free of
state of many of this bacteria. tuberculosis, no bacterial DNA
These forms are highly variable could be detected.
and include small phases that can
be filtered, vacuoles, granules, The treatment of tuberculosis and
acid-labile and acid-stable rods, other so-called “tuberculinic
up to fungus-like structures with diseases”, such as degenerative
hyphen and mycelia. Dostal diseases (MS, Parkinson, diabetes
already noted in 1910 (Wiener etc.) or cancers has for decades
Medizinische Wochenschrift, p. successfully included the iso-
2100, 1910): “I now tend to think pathic-homeopathic SANUM
that the tubercle bacilli are the preparation NIGERSAN, in
parasitic states of certain addition to the indispensable
m o l d s ” [ c i t a t i o n f ro m t h e milieu therapy, for instance by
publication of Harmsen]. correcting the cell respiration,
correcting the acid-base equil-
The long persistence of the ibrium, correcting the electrolyte
Mycobacterium tuberculosis balance, and immuno-modulation.
DNA in normal lung tissue This preparation was developed
without histological detection was by Enderlein and contains colloids
recently confirmed in a study by from the mold Aspergillus niger.
Norwegian researchers (R. Its activity is thought to involve
Hernández-Pando et al.: degradation through copulation of
“Persistence of DNA from the Mycobacterium tuberculosis
mycobacterium tuberculosis in which, according to Enderlein, is
superficially normal lung tissue a highly developed phase of
during latent infection”, The Aspergillus, by the lower

Semmelweis-Institut GmbH
Verlag für experimentelle Onkologie GmbH · 27316 Hoya · Germany
11