MO - Question Paper
MO - Question Paper
Phosphatidylinositide system commence with activation of phospholipase-C which Activation of IP3 by action Increase in intracellular ca2+ Release of diacylglycerol Activation of
17
undergo a sequence of even except of a phosphatases concentration (DAG) from a phospholipid protein kinase-C
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Inhibiting vesicular
Inhbiting synthesis of Inhibiting neuronal uptake inhibiting release of
21 Botulinum toxin produce skeletal muscle paralysis by incorporation
Acetylcholine of choline neuronal acetylcholine
acetylcholine
This anticancer agent produces a type of megalobastosis that is unresponsive to both
22 Mechlorethamine Cladribine Hydroxyurea Temozolomide
Vit B-12 and folic acid
Tubular transport
Plasma protein level is Drug metabolizing enzymes Glomerular fillration rate
23 The plasma half life of penicillin- G is longer in the new born because their mechanisms are not
low are immature is low
well developed
Patient treated with the following anticancer drug are likely to develop a disulfiram
24 Dacarbazine Procarbazine Melphalan Hydroxyurea
like reaction on taking alcohol
25 Hepatic first-pass can be avoided in all of following routes except Per-rectal Transdermal Per-Oral Sublingual
Apparent volume of
26 Loading dose of a drug is detemined by the Clearance of the drug Dosing rate Accumulation factor
distribution of the drug
27 Which of the following is CCK-receptor antagonist Loxiglumide Tegaserod Fedotozine Leuprolide
28 Filgrastim is indicated for Neutropenia Aplastic anaemia Thrombocytopenia Eosinophilia
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Lithium can
precipitate
Lithium has a volume of Lithium can produce extrapyramidal
It produces postural tremor
29 Identify the wrong statement regarding lithium distribution of around 40 Vasopression Resistant symptoms when
of 8 to 12 Hz
liters Diabetes insipidus used with atypical
narcoleptics such as
Risperidone
30 Which 'thiazide' diuretic has the highest relative potency Chlorothiazide Polythiazide Metolazone Chlorthalidone
It blocks cell cycle
It plays a role in up to 50 It is involved in causation of It’s a tumour
31 Which of the follwing is not true for the p53 gene? progression in response to
% of human cancers retinoblastoma suppressor gene
DNA damage
The rate-controlliing enzyme of the mevalonate pathway, response for cholesterol AcetoacetyL CoA
32 GeranyL transferase Squalene synthase HMG CoA reductase
biosynthesis is thiolase
Protein
33 The membrane Attack Complex of the complement system is also known as the C5b5678 complex C5b6789 complex C5b5789 complex polysaccharide
complex
Inherited mental Robertsonian Defect in FMR 1
34 Which of the following is NOT related to fragle X syndrome? Trinucleotide repeat
retardation translocation gene
Leads to increased Is classically seen in
Occurs in the starvation Encourages biosynthesis of
35 Which of the following statements is correct about the high insulin/glucagon ratio concentrations of ketone patients with
state proteins
bodies in the blood diabetes
The glyoxylate cycle utilizes following enzymes associated with tricarboxylic acid cycle
36 Succinate dehydrogenase Isocitrate lyase Maltase dehydrogenase Acotinase
except
37 Fat -Soluble vitamins are B, C and D B, D and E A, B and C A,D and E
Posterior vena cava,
caudal vein, kidney, liver , Intestine, liver, hepatic vein, Kidney , liver, intestine, intestine, liver,
38 The sequence of flow of blood in the hepatic portal system of a mammal is
posterior vena cava Inferior vena cava sinus venosus hepatic vein , sinus
venosus
39 Which of the following antibody first reaches the site of infection? IgA IgE IgG IgM
p21 (aCdk inhibitior
40 The gene for which of the following would be considered a proto-oncogene ? p53 Rb protein Ras
protein)
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50 Which of the following fungi is capsulated ? Candida albicans aspergillus fumigatus Ceyptococeus neoformans None of the above
A form of death that results from exclusion of air from the lungs by means other than
51 Hanging Throttling Suffocation Garrotting
compression of the neck is called
A disturbance of consciousness where orientation is impaired, critical faculty is
52 Illusion Delusion Delirium Dementia
Blunted and thought content is irrelevant is called
53 The certain sign of pregnancy is Foetal heart sound X-ray and ultrasound Foetal movement Uterine souffle
54 The Certain sign of death is Rigor mortis Hypostasis Marbling Decomposition
Prominence of superficial Greenish discolouration of Development of foul Appearance of
55 The earliest external sign of putrefication is
veins iliac fossa smelling gases Hypostasis
Unsworn evidence without administration of oath is admissible in court if the age of
56 18 Yrs 16 yrs 14 yrs 12 yrs
the person is below
Umbilical cord
Foetus shows intrauterine
57 Hydrostatic test is not necessary in all of the following except Stomach contains milk Diaphragm at 6th or 7th rib cicatrised and
maceration
separated
58 Risus sardonicus is a feature of poisoning by Digitalis Strychnine Semecarpus Ricinus
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Falling of hair of the head on third week of onset of symptoms is a diagnostic feature Chronic Thallium Chronic Mercury Chronic Copper
59 Chronic Lead poisoning
of poisoning poisoning poisoning
Chronic strychnine Chronic Dhatura
60 feeling of grains of sand or insects crawling under the skin is a feature of Chronic opium poisoning Chronic cocaine poisoning
poisoning poisoning
61 Emprostotonus is a feature of poisoning by Cocaine Curare Strychnine Physostigmine
Chronic antimony Chronic Zinc
62 Hyperpigmentation and hyperkeratosis of palm and sole is a feature of Chronic arsenic poisoning Chronic Iron poisoning
poisoning Poisoning
63 Majun is a preparation made from Papaver Cannabis Cocaine Atropa
64 Dark brown colour of hypostasis is found in poisoning by Carbon monoxide Phosphorus Potassium Chlorate Aniline
65 Which of the following is not a presumptive sign of pregnancy Cessation of menses Morning senses Ballottement Quickening
SBP≥140 mm Hg
WHR >0.9 for males or Albumin excretion of < 20 Low levels of HDL
66 Metabolic Syndrome does not include or DBP≥90 MM
<0.85 for females mg cholesterol
HG
The revised target for HFA by 2020 in respect of maternal mortality ratio is to bring it
67 0.5 / 1000 1.0 / 1000 3.0 / 1000 5.0 / 1000
down to:
Under IDSP, which one of the following is <b><u>NOT</u></b> a group of diseases in Vaccine
68 Sexually transmitted Vector borne Water borne
the category of "Regular Surveillance" preventable
Incidence and mortality Incidence rates will be There will be no
Patients with lung cancer die within a very short duration after the onset of the Mortality rate will be higher
69 will be almost similar in a higher than mortality relationship
disease. Which one of the following is true for lung cancer ? than the incidence
year rates between the two
70 In India the most efficient vector of plague is X. brasileinsis X. astia X. Cheopis P. Irritans
71 Which one of the following is <b><u>NOT</u></b> a one-way communication ? Symposium Lecture Group discussion Stage Show
Bias, Chance,
Confounding, chance, Chance, Confounding, Bias, Criteria of casual
what is the correct sequence of excluding the role of certain factors while assessing confounding,
72 criteria of casual Criteria of casual association, bias,
the relationship between cause and effect ? criteria of casual
association, bias association confounding, chance
association
Which one of the following is <b><u>NOT</u></b> a method of controlling a Using accurate Attempting Stratified Performing
73 Employing Restriction
confounding factor ? instruments analysis Matching
74 Saddle shaped pattern of fever is seen in kala-azar malaria Dengue Typhoid
Drug X, widely used as an NSAID, was banned from being sold following reports of Assessment of a multi drug Assessment of adverse Phase IV of a
75 Phase II of a clinical trial
adverse cardiovasular effect. This is an Example of trial effect in a multidrug trial Clinical trial
Colle's fractuer in Institutional normal
76 In a case -control study, survivorship bias is most likely for Myocardial infraction Coryza
sportspersons deliveries
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The emission of which gas is checked during a pollution under control (PUC) Checked
77 Sulphur dioxide Nitrogen Dioxide Carbon Monoxide Particulates
?
78 Jaggery is a rich source of Carotene & thiamine Zinc & iron Iron & carotene Sugar & proteins
79 The most well-proven, and maximum risk of cancer due to obesity is for Uterine endometrium colon Breast Stomach
80 Worldwide , the most common cause of death from cancer is due to cancer of the LUNG Oral Cavity Stomach Liver
A 17 years youth presnts with purpuric rash on his leg and buttock. There is joint pain
Thrombotic
and a vomit containing cofee grounds. Blood testing reveals mild rise in in IgA levels. Hencoch-Schonlein
81 Thrombocytopenic Traumatic injury Polyateritis nodosa
Urine testing reveals microscopic haematuria.What diagnosis fits to this clinical purpura
purpura
picture ?
82 One melanocyte has contact with 12Keratinocyte 16Keratinocyte 30Keratinocyte 36Keratinocyte
83 Which Sebaceous gland located on areola? Montgomery's tubercles Tyson's gland Zeis gland Meibomian gland
84 Langerhans cell originate from? Ectoderm Mesoderm Neural crest Lymph nodes
20wk Pregnant
30wk Pregnant women 30wk Pregnant women
The highest risk of fetal varicella syndrome in pregnant women would be associated 20wk Pregnant women who women who
85 who developed herpes who developed varicella
with which of following scenario ? developed herpes zoster . developed varicella
zoster . infection
infection
86 In comparison to other isotopes, hydrogen is most useful for MRI because Low isotopic abundance High magnetic susceptibility High tissue concentration Low spin density
87 In MRI a square field of view (FOV) reduces Signal to Noise Ratio by 1/2 1/4 3/4 1/8
88 Right sided isomerism is associated with all except Trilobed lungs Polysplenia Central Liver Malrotation
Discontinuity of
89 Finding of diaphragm rupture on CT included all except Collar sign Dependent viscera sign Fallen lung sign
diaphragm
90 In mammogram the following terms are used to describe benign calcification except Popcorn Linear, branching Eggshell Central lucent
Maxilla and
Lack of mesenchymal Cell death in trigeminal Exposure to high level of
91 Treacher collins syndrome is characterised by following facts except mandible
tissue gangalia ethanol
underdeveloped
92 Mostly Maxillary permanentcanine erupted in Oral cavity at the age of 6-7 Years 8-9 Years 9-10 Years 11-12 Years
Parotid gland is largest Sublingual gland is serous Submandibular gland is Parotid gland is
93 Point out wrong statement about three bilaterally paired major salivary gland
salivary glands gland . mixed gland serous glands
High Flouride content in Low Flouride content in Hyper calcification of Hypercalcification
94 Mottled enamel is due to
water Water Enamel of dental pulp
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Superficial
manifestation of
141 paget diasease of the nipple of breast is Eczema Dermatitis Necrotising infection
underlying
carcinoma
Non -functioning
142 Incidentaloma of adrenal gland are commonly Adreno cortical carcinoma Pheochromocytoma Cushing's adenoma
adenomas
143 Which is not a complication of Ileostomy? Retraction Fistulation Malignancy Bleeding
Present in about 2% 2 feet from ileocaecal
144 Which is not true for Meckle's diverticulum? 2 inches Long 2 cm diameter
population junction
Gastro-esophageal reflux
145 Succussion splash is usually seen in Biliary stricture Gastric outlet obstruction Acute pancreatitis
disease
146 Flouoro deoxy glucose (FDG) is commonly used in CECT PET MRI DSA
Cholangio
147 Helicobacter pylori is commonly associated with GERD Carcinoma stomach Gall Stones
carcinoma
148 Which is not a cause of hypercalcaemia? Parathyroid adenoma Obesity Prolonged immobilisation Sarcoidosis
Polycystin-1 and
An autosmal dominant Usually manifest in
149 Which is not true for polycystic disease of kidney? Multisystem disorder polycystin-2 proteins play
disease first decade of life
an impotant role
Social and religious
150 Which is not an indication of circumcision? Recurrent balanoposthitis Phimosis Carcinoma penis
reasons
Reactive bone formation Malignant bone formed by Bone formed due to Bone formed due to
151 Codman's triangle seen on radiograph in ostegenic sarcoma is
by normal periosteum tumour osteoblasts dystrophic ossification myositis ossificans
152 Nerve root supply of hip abduction is L 1,2 L 2,3,4 L 4,5,S1 L5, S1
Supra spinatus
153 Calcium pyrophosphate dihydrate causes Gout Pseudogout Haglund's disease
calcification
Child supports the
It is downward dislocation Common under the age of 6 Elbow is fully extended
154 Regarding 'Pulled Elbow', the following statement is FALSE limb in flexin and
of radial head years and pronated
supination
Baseball pitcher's
155 Chronic injury to medical collateral ligament of elbow is termed Tennis elbow Golfer's elbow Javelin thrower's elbow
elbow
156 Avascular necrosis of scaphoid is known as Kienbock's disease Preiser's disease Kohler's disease Frieberg's disease
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157 Confirmatory sign of sciatic nerve tension is Lasegue's test Braggards test Browstring sign Neri's test
158 In circulatory shock, the following is not due to reduction in cardiac output Distributive shock Hypovoluemic shock Obstructive Shock Cardiogenic Shock
Anterior dislocation of Fracture dislocation of Posterior dislocation of Inferior dislocation
159 Electric light bulb' appearance on radiograph is characteristic of
shoulder proximal humerus shoulder of shoulder
As regards femoral shaft fracture , if the butterfly fragment involves more than 50
160 Type 1 Type 2 Type 3 Type 4
percent of bone width, Winquist classifies it as
Juvenile respiratory papillomatosis is most commonly caused by human papilloma
161 Type 2 Type 18 Type 6 Type 31
virus
Mastoid emissary
162 Griesoinger's sign is present due to thrombosis of Internal Jugular Vein Canvernous sinus Sagittal sinus
vein
163 All are pre cancerous conditions except Amyloidosis Keratosis Leukoplakia Papilloma
Located on the
Arises from cervical Lies within the caritid anterior surface of
164 All are true about phrenic nerve except Supplies the diaphragm
nerves 3,4,5 sheath the anterior scalene
muscle
Second bronchial
165 Most common congenital anomaly of the Branchial system Cystic Hygroma First Branchial cleft cyst Thyroglossal duct cyst
cleft cyst
166 Rider are commonly seen in Blue dot cataract Zonular cataract anterior polar cataract coronary cataract
posterior subcapsular anterior subcapsular
167 Polychromatic lusture is seen in Zonular cataract nuclear cataract
cataract cataract
168 Lens capsule is thinnest at the Centre anteriorly Center Posteriorly at equater Superiorly
169 Neuroparalytic keratitis is caused by paralysis of Optic nerve Trigeminal nerve facial nerve oculomotor nerve
170 recurrent corneal erosion is a feature of Keratoglobus keratoconus glaucoma corneal dystrophy
Injection of
Injection of uterotonic
Delivery of the placenta uterotonic after 1
171 Which is not true about active management of third stage of labour (AMTSL)? within 1 Minute of Clamping the cord
by controlled cord traction minute of delivery
delivery of the fetus
of the fetus
172 Which of the following is not a sign of pregnancy ? Hingorani Sign Goodell's Sign Osiander's sign Jacquemier's Sign
173 Which vaccine can be given safely during pregnancy Rubella vaccine Rabies vaccine Yellow fever vaccine Varicella vaccine
Intrauterine contraceptive Combined oral
174 Which contraceptive methods are not ideal for a lactating woman after delivery ? Progestin only pill Barrier method
device(IUCD) contraceptive(COC)
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0<sup>th</sup> , 0<sup>th</sup> , 1
0<sup>th</sup>, 0<sup>th</sup> ,
What is the correct dosing pattern of Quadrivalent HPV vaccine to a girl of 16 years of <sup>st</sup>and
189 2<sup>nd</sup> and 3<sup>rd</sup> and 4<sup>th</sup> and
age ? 6<sup>th</sup>mo
6<sup>th</sup> months 6<sup>th</sup> months 6<sup>th</sup> months
nths
190 Which of the following is used as an emergency contraception? levonorgestrel Cabergolin Letrozole Metformin
During spinal anaesthesia using midline approach, the spinal needle penetrates all Posterior longitudnal Supraspinous
191 Ligamentum flavum Intraspinous ligament
layers, except ligament ligament
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