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Post Lab 1 and 2

This document provides instructions for preparing peppermint water and cinnamon water using direct solution and alternative solution methods. It includes the objectives, materials, synonyms, official descriptions, uses, formulations, procedures, labels, preparation methods, dosage forms, and questions for each preparation. The procedures involve shaking or agitating the volatile oils in water and purifying the solutions by filtering.

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Nikol Baltazar
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590 views5 pages

Post Lab 1 and 2

This document provides instructions for preparing peppermint water and cinnamon water using direct solution and alternative solution methods. It includes the objectives, materials, synonyms, official descriptions, uses, formulations, procedures, labels, preparation methods, dosage forms, and questions for each preparation. The procedures involve shaking or agitating the volatile oils in water and purifying the solutions by filtering.

Uploaded by

Nikol Baltazar
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd
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PHARMACEUTICS I LABORATORY

Name: ______________________________________________ Date:_______________________

Year/Course : _______________________________________

PREPARATION NO. 1: PEPPERMINT WATER

I. OBJECTIVES:
- To prepare Peppermint Water by Direct Solution Method

II. MATERIALS:
 Erlenmeyer flask with cork/stopper,
 Dropper
 Graduated cylinder 60 mL
 Amber bottle
 Funnel
 Filter paper
 Labeling materials

III. SYNONYMS:
- Aqua menthae piperitae, Aqua Mint, American Mint

IV. OFFICIAL DESCRIPTION: ( 3 pts)


- a clear saturated aqueous solutions of peppermint oil

V. USE/S ( 2pts)
- Flavorant
- Carminative

VI. FORMULATION:

Name of Ingredients Original Amount Computed Amount


Peppermint Oil 2 mL
Purified water qs. ad. 1000 mL

VII. COMPUTATIONS:

Peppermint oil = 10ml =


2 ml x __________ 0.02 ml (5 pts)
1000ml
ml

Purified water = qs. ad ( sufficient quantity to make ) , 10ml – 0.02ml = 9.98 ml (3 pts)
PHARMACEUTICS I LABORATORY

VIII. PROCEDURE
1. Shake two (2) mL peppermint oil with 1000 mL of purified water in a container of sufficient
capacity.
2. Repeat the shaking, several times during a period of 15 minutes
3. Set aside for 12 hours or longer
4. Filter through wetted filter paper and add purified water through the filter to make the product
measure 1000 mL

IX. LABEL

- WHITE LABEL (2pts)

X. METHOD OF PREPARATION

- DIRECT SOLUTION METHOD (2pts)


-
XI. TYPE OF DOSAGE FORM

- SOLUTION (2pts)

XII. QUESTIONS:

1. Define Aromatic waters? (3pts)

 defined in the USP as clear, saturated aqueous solutions of volatile oils or other aromatic or volatile
substances.

2. What is the other name of aromatic water? (3pts)

 Mediacted water

3. What is cohobation? (3pts)

 is the process of obtaining aromatic water by distillation one or more times from delicate drugs
with small quantities of volatile principles.

.
PHARMACEUTICS I LABORATORY

Name: ______________________________________________ Date:_______________________

Year/Course : _______________________________________

PREPARATION NO. 2: CINNAMON WATER

I. OBJECTIVES:
- To prepare Cinnamon Water by Alternative Solution Method

II. MATERIALS:
 Erlenmeyer flask with cork/stopper,
 Dropper
 Graduated cylinder 60 mL
 Amber bottle
 Funnel
 Filter paper
 Labeling materials

III. SYNONYMS: (3pts)


- Casio Nare,
- Cassia Oil
- Aqua Cinnamoni

IV. OFFICIAL DESCRIPTION: (2pts)


- a clear saturated aqueous solutions of peppermint oil

V. USE/S (3pts)
- flavored vehicle for internal aqueous solution,
- antiseptic in eye lotion,
- carminative
PHARMACEUTICS I LABORATORY

VI. FORMULATION:

Name of Ingredients Original Amount Computed Amount


Cinnamon Oil 2 mL
Talc 15 g
Purified water qs. ad. 1000 mL

VII. COMPUTATIONS:
10 ml
Cinnamon oil = 2 ml x __________ = 0.02 ml (5 pts)
1000ml
ml
10 ml
Cinnamon oil = 15g x __________ = 0.15 g (5 pts)
1000ml
ml
Purified water = qs. ad ( sufficient quantity to make ) , 10ml – 0.17ml = 9.83 ml (3 pts)

VIII. PROCEDURE
1. Incorporate thoroughly the volatile oil with 15 g of Talc or with a sufficient quantity of talc or
pulped filter paper.
2. Agitate the mixture several times during 10 minutes with 1000 mL of purified water.
3. Filter, return first portion if necessary to obtain clear filtrate.
4. Add sufficient amount of purified water through the filter to make the product measure 1000 mL .

IX. LABEL
- WHITE LABEL (2pts)

X. METHOD OF PREPARATION

- ALTERNATIVE SOLUTION METHOD (2pts

XI. TYPE OF DOSAGE FORM


- DIRECT SOLUTION METHOD (2pts
PHARMACEUTICS I LABORATORY

XII. QUESTIONS:

1. Give the botanical origin of cinnamon ?


- Cinnamomum Zeylanicum
- Cinnamomum loureii
- Cinnamomum cassia

2. Why is there a difficulty in producing clear of aromatic water?

- The difficulty encountered in the compounding of prescriptions containing aromatic


waters is due to a “salting out” action of certain ingredients, such as very soluble salts
in the volatile principle of the aromatic water.

3. Why light resistant container are used for packaging aromatic waters?

- Aromatic waters should be made in small quantities and protected from intense light and
excessive heat as they deteriorate with time. Deterioration may be caused by volatilization,
decomposition or mold growth resulting to solution that are cloudy and have lost all traces of
their agreeable odor.

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