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Calculation of Drug Dosage & Solution: Conversion Temperature

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52 views3 pages

Calculation of Drug Dosage & Solution: Conversion Temperature

Uploaded by

Lea Ioa
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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Download as PDF, TXT or read online on Scribd
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CALCULATION OF DRUG DOSAGE & SOLUTION

CONVERSION TEMPERATURE
1 kg = 2.2 lbs FARENHEIT (F) to
1 g = 1,000 mg CELSIUS/CENTRIGRADE (C)
1 g = 1,000,000 mcg 5
1 mL = 15-20 gtts (depending on drop ℉ − 32 × 9 = ℃
factor)
CELSIUS/CENTRIGRADE (C) to
1 gtt = 4 mcgtts
FARENHEIT (F)
1 tsp = 5 mL
1 grain = 60 mg 9
× ℃ + 32 = ℉
1 inch = 2.54 cm 5
1 tbsp = 3 tsps = 15 mL

SYMBOLS ON FORMULA
D- desired dose or ordered dose
S- stock or on hand date
V-volume or diluent
A- amount of drug calculated to be given to patient

ORAL DOSAGES
𝑑𝑒𝑠𝑖𝑟𝑒𝑑 𝑑𝑜𝑠𝑒 𝐷
= 𝑎𝑚𝑜𝑢𝑛𝑡 𝑡𝑜 𝑔𝑖𝑣𝑒 OR =𝐴
𝑠𝑡𝑜𝑐𝑘 𝑑𝑜𝑠𝑒 𝑆
𝑑𝑒𝑠𝑖𝑟𝑒𝑑 𝑑𝑜𝑠𝑒 𝐷
× 𝑣𝑜𝑙𝑢𝑚𝑒 (𝑞𝑢𝑎𝑛𝑡𝑖𝑡𝑦) = 𝑎𝑚𝑜𝑢𝑛𝑡 OR ×𝑉 = 𝐴
𝑠𝑡𝑜𝑐𝑘 𝑑𝑜𝑠𝑒 𝑆

PARENTERAL DOSAGES
𝑑𝑒𝑠𝑖𝑟𝑒𝑑 𝑑𝑜𝑠𝑒 𝐷
= 𝑎𝑚𝑜𝑢𝑛𝑡 𝑡𝑜 𝑔𝑖𝑣𝑒 OR =𝐴
𝑠𝑡𝑜𝑐𝑘 𝑑𝑜𝑠𝑒 𝑆
𝑑𝑒𝑠𝑖𝑟𝑒𝑑 𝑑𝑜𝑠𝑒 𝐷
× 𝑣𝑜𝑙𝑢𝑚𝑒 (𝑞𝑢𝑎𝑛𝑡𝑖𝑡𝑦) = 𝑎𝑚𝑜𝑢𝑛𝑡 OR ×𝑉 = 𝐴
𝑠𝑡𝑜𝑐𝑘 𝑑𝑜𝑠𝑒 𝑆

Important Note:
ROUTE IF STOCK DOSE GIVEN IS DILUTED TO (IV)/MAX. ADMINISTRATION (IM)
500 mg DILUTE TO 5 mL
For IV
1000 mg DILUTE TO 10 mL
500 mg ONLY 1 mL IS ADMNISTERED
For IM
1000 mg ONLY 2 mL IS ADMINISTERED
CALCULATION OF DRUG DOSAGE & SOLUTION

IV REGULATION
DROP FACTOR (If not given, automatic 15 gtts/min)
- Macroset (10, 15, 20)
- Microset (60)

SOLUTIONS

𝒎𝑳 𝑎𝑚𝑜𝑢𝑛𝑡 𝑡𝑜 𝑏𝑒 𝑖𝑛𝑓𝑢𝑠𝑒𝑑 𝑖𝑛 𝑚𝐿
= Note:
𝒉𝒓 # 𝑜𝑓 ℎ𝑜𝑢𝑟𝑠 𝑡𝑜𝑡𝑎𝑙 𝑖𝑛𝑓𝑢𝑠𝑖𝑜𝑛 𝑡𝑖𝑚𝑒 𝑚𝐿 𝑚𝑐𝑔𝑡𝑡𝑠
= (𝑂𝑛𝑙𝑦 𝑖𝑓 𝑑𝑟𝑜𝑝 𝑓𝑎𝑐𝑡𝑜𝑟 𝑖𝑠 𝟏𝟓)
𝑎𝑚𝑜𝑢𝑛𝑡 𝑡𝑜 𝑖𝑛𝑓𝑢𝑠𝑒 ℎ𝑟 𝑚𝑖𝑛
# 𝒐𝒇 𝒉𝒐𝒖𝒓𝒔 =
ℎ𝑜𝑢𝑟𝑙𝑦 𝑟𝑎𝑡𝑒 1 gtt = 4 mcgtts
𝒈𝒕𝒕𝒔 𝑚𝐿 𝑔𝑡𝑡 𝑓𝑎𝑐𝑡𝑜𝑟 1 ℎ𝑟 Shorcuts:
= × ×
𝒎𝒊𝒏 ℎ𝑟 1 𝑚𝐿 60 𝑚𝑖𝑛
𝑚𝐿
1.
𝑔𝑡𝑡𝑠
= ℎ𝑟⁄
𝒎𝑳 # 𝑜𝑓 𝑚𝐿 𝑝𝑒𝑟 ℎ𝑜𝑢𝑟 𝑚𝑖𝑛 4
=
𝒎𝒊𝒏 60
𝑚𝐿 𝑡𝑜𝑡𝑎𝑙 𝑚𝐿
𝒎𝒄𝒈𝒕𝒕𝒔 𝑔𝑡𝑡𝑠 4 𝑚𝑐𝑔𝑡𝑡𝑠 2. =
ℎ𝑟 ℎ𝑟𝑠 𝑜𝑓 𝑖𝑛𝑓𝑢𝑠𝑖𝑜𝑛
= ×
𝒎𝒊𝒏 𝑚𝑖𝑛 1 𝑔𝑡𝑡

TITRATION
BY DOSAGE

% ∶ 100 𝑚𝐿 ∶: 𝑎𝑚𝑜𝑢𝑛𝑡 𝑜𝑓 𝑑𝑟𝑢𝑔𝑠 𝑖𝑛 𝑔𝑟𝑎𝑚𝑠 ∶ 1𝑚𝐿 𝑜𝑓 𝐻20


(𝑐𝑜𝑛𝑠𝑡𝑎𝑛𝑡) (𝑋) (𝑐𝑜𝑛𝑠𝑡𝑎𝑛𝑡)

BY FLOW RATE
𝑔𝑡𝑡𝑠
𝐼𝑉𝐹 𝑖𝑛 𝑔𝑡𝑡𝑠 ∶ 𝑎𝑚𝑜𝑢𝑛𝑡 𝑜𝑓 𝑑𝑟𝑢𝑔 𝑡𝑜 𝑏𝑒 ∶: 𝑋 ( ) : 𝑎𝑚𝑜𝑢𝑛𝑡 𝑜𝑓 𝑑𝑟𝑢𝑔 𝑡𝑜 𝑏𝑒
𝑚𝑖𝑛
𝑖𝑛𝑐𝑜𝑟𝑝𝑜𝑟𝑎𝑡𝑒𝑑 𝑖𝑛 𝐼𝑉𝐹 𝑑𝑒𝑙𝑖𝑣𝑒𝑟𝑒𝑑 𝑝𝑒𝑟 𝑚𝑖𝑛𝑢𝑡𝑒
𝑖𝑛 𝑚𝑔
For DOSAGE Steps: For FLOW RATE STEPS
1. Get the stock dose (in mg) 1. Get the stock dose (BASICALLY
2. Amount to give (V= 1 mL) STEP 1 AND 2 of DOSAGE)
𝐷 2. Get flow rate
3. 𝑆 × 𝑎𝑚𝑝𝑢𝑙𝑒 = 𝐴𝑚𝑝𝑢𝑙𝑒𝑠
CALCULATION OF DRUG DOSAGE & SOLUTION

PREPARING A SOLUTION (Mind only the %)


% ∶ 100 𝑚𝐿 ∶: 𝑎𝑚𝑜𝑢𝑛𝑡 𝑜𝑓 𝑑𝑟𝑢𝑔𝑠 𝑖𝑛 𝑔𝑟𝑎𝑚𝑠 ∶ 1𝑚𝐿 𝑜𝑓 𝐻20
(𝑐𝑜𝑛𝑠𝑡𝑎𝑛𝑡) (𝑋) (𝑐𝑜𝑛𝑠𝑡𝑎𝑛𝑡)

Note:
If looking for grams, it’s just the decimal figure of the %. (Ex. 20% = 0.2 g)
If looking for mg, % × 10 mg. (Ex. 20% = 200 mg)

PEDIATRIC CALCULATIONS
BY BODY WEIGHT
𝐷
1ST STEP: × 𝑉 = 𝐴
𝑆

2ND STEP: PARAMETERS


𝑚𝑔
× 𝑤𝑒𝑖𝑔ℎ𝑡 (𝑘𝑔) = 𝑚𝑔/𝑑𝑎𝑦
𝑘𝑔
𝑚𝑔 1 𝑑𝑎𝑦
× = 𝑚𝑔/𝑑𝑜𝑠𝑒
𝑑𝑎𝑦 # 𝑜𝑓 𝑑𝑜𝑠𝑒𝑠

BY BODY SURFACE AREA (Either of the equations)

ℎ𝑒𝑖𝑔ℎ𝑡 (𝑖𝑛)×𝑤𝑒𝑖𝑔ℎ𝑡 (𝑙𝑏)


1. 𝐵𝑆𝐴 = √
3131 (𝑐𝑜𝑛𝑠𝑡𝑎𝑛𝑡)
𝑠𝑢𝑟𝑓𝑎𝑐𝑒 𝑎𝑟𝑒𝑎 𝑖𝑛 𝑠𝑞.𝑚𝑒𝑡𝑒𝑟
2. 𝐶ℎ𝑖𝑙𝑑 ′𝑠 𝐷𝑜𝑠𝑒 = 1.73 𝑠𝑞.𝑚𝑒𝑡𝑒𝑟
× 𝐴𝑣𝑒. 𝑎𝑑𝑢𝑙𝑡 𝑑𝑜𝑠𝑒

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