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Antioxidant Activity: Pseudomonas Aeruginosa

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35 views2 pages

Antioxidant Activity: Pseudomonas Aeruginosa

Uploaded by

john mwangi
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© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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Antioxidant activity

The antioxidant activity is the ability to inhibit the deleterious effects of free radicals such as

lipid peroxidation by the antioxidant molecules. The free radicals that may be of both nitrogen

and oxygen based are very reactive due to the characteristic presence of unpaired electrons.

These radicals are produced under normal physiological process and also under influence of

other factors such as smoking of tobacco or exposure to radiations (Valko et al., 2007). These

radicals are very important when under normal concentration. However, under increased

concentrations they result into imbalance that cause condition known as oxidative stress that is a

player in chronic disorders such as cancer. Antioxidants are key in controlling this condition by

either inhibiting, terminating the chain reactions or scavenging the excess free radicals

(Lourenço et al., 2019).

Natural antioxidants from obtained from plant materials and other natural sources include

polyphenols such as flavonoids, anthocyanins, lignans, and carotenoids, essential oils and

vitamins. These antioxidant are very viatla nad have greatl contributed to the reduction of many

chronic conditions that are witnessed in many people. On addition these antioxidant sources have

been regarded safer and potent as well (Lobo et al., 2010).

Bacteria
Pseudomonas aeruginosa
It’s a gram negative and fucultatively aerobic bacterium that can cause disease in plants and

animals. Generally it infects immunocompromised but can also affect immunocompetent

persons. It’s difficult to treat because of its natural resistance to antibiotics (Gellatly & Hancock,

2013).

It’s found in soil, water, skin flora and most man made environments throughout the world.

Symptoms of infection include inflammation and sepsis. Pseudomonas causes 10-20% infections
especially in patients with burn wounds, cystic fibrosis, acute leukaemia, organ transplant and IV

drug addiction (Gellatly & Hancock, 2013).

Staphylococcus aureus
It’s a gram positive bacterium found in the upper respiratory tract and on the skin. These bacteria

are spread by having direct contact with an infected person, by using a contaminated object or by

inhaling infected droplets dispersed by coughing and sneezing (D.lowy & M.D., 1998).

Staphylococcus infections are caused by staphylococcus bacteria. Staphylococcus aureus causes

a wide range of infections. It’s the leading cause of blood stream infection, bacteraemia,

infective endocarditis, it also causes osteoarticular, skin and soft tissue, pleuropulmonary and

device related infections (Rasigade & Vandenesch, 2014).

Strains of bacteria that are resistant to almost all beta lactam antibiotics are called methicillin

resistance staphylococcus aureus MRSA. Methicillin is a type of penicillin (Chambers, 2005).

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