DRUG STUDY

NAME OF CLASSIFICATION SPECIFIC INDICATION CONTRAINDICATION ADVERSE

ADVERSE NURSING
NURSINGRESPONSIBILITIES
RESPONSIBILITIES
DRUG ACTION EFFECTS
EFFECTS
Cefuroxime750m
Piperacillin+Taz Therapeutic Class:
Anti-Infective Beta- Inhibits cell-wall
Anti-bacterial Surgical
Prophylaxis Hypersensitivity
Hypersensitivitytoto  Headache
Phlebitis  Determine
Obtain historyhistory
of hypersensitivity
of
gobactam
IVTT q 8hrs Lactam Antibiotic;
Antibiotics combination
synthesis, against microbial
prophylaxis cephalosporins
piperacillin, and  Insomia
Thrombophlebitis to penicillins, cephalosporins,
hypersensitivity reactions to or
Antipseudomonal product consisting
promoting osmotic activity or
reducing related
tazobactam,
antibiotics.  Fever
penicillins, Diarrhea other drugs priorpenicillins
cephalosporins, to and
Dose: 750mg
4.5 mg Penicillin
Pharmacological of the
instability; usually eliminating  Seizures
cephalosporins, or beta- Pseudomembrano administration.
history of allergies, particularly to
Route: IVTT Class: Second semisynthetic and
bactericidal. infection. lactamase inhibitors  Agitation
us colitis  drugs,
Considerbefore
the 12therapy
Rightsisofinitiated.
Frequency: q 8hrs generation the beta-lactamase such as clavulanic acid Dizziness
Nausea administering medication
ANST cephalosporins inhibitor and sulbactam.  Chestpain
Anorexia  Consider
Lab Tests:the C&S12 Rights
prior tooffirst dose
tazobactam,  Edema
Vomiting of the drug; start
administering medication
drug pending
Tazobactam  Contraindicated in  Hypertension
Hemolytic anemia results.
component does patients hypersensitive  Tachycardia
Thrombocytopeni  Inspect
MonitorIV hematologic
injection sites
status with
NAME OF GENERAL not decrease the to the drug or other  Diarrhea
a prolonged therapy
frequently for signs(Hctof phlebitis
and Hgb,
SPECIFIC
activity ofACTION
the INDICATION CONTRAINDICATIO
penicillins. ADVERSE
 Constipation
Macupapular and NURSING RESPONSIBILITIES
CBC with differential and platelet
DRUG ACTION
piperacillin N  NauseaEFFECTS rash  Monitor
erythematous count) signs and symptoms of
component  Vomiting  superinfection
Omeprazole Therapeutic Inhibits proton against
pump  Short term  Contraindicated with
Urticaria
 Headache
Monitor patientand carefully
 Consider the 12 Rights of
diarrhea.
during
susceptible  Dyspnea
Pain the first 30mins after initiation of
40mg IVTT OD Class: Antiulcer activity by binding to treatment of hypersensitivity to  Asthenia administering medication
organisms.  Dyspepsia
Anaphylaxis  Advise
the infusion
patientfortosigns
report
of
drugs hydrogen-potassium active duodenal omeprazole or it’s  Vertigo
 Pseudomembranous
Hypersensitivity hypersensitivity.
discomfort at IV insertion site
adenosine and ileal ulcer components  Colitis
Insomnia  Verify doctor’s written
reaction  Report rash, itching, or other
Pharmacological triphosphatase, located  Use cautiously in prescription
  Skin
Apatahy
SerumRash
sickness  Document
signs of hypersensitivity
that drug was given
Class: Proton at secretory surface of  Short term patients with
  Pruritus
Anxiety immediately.
Pump Inhibitors gastric parietal cells, treatment of hypokalemia  Inform
to suppress gastric   Hypersensitivity
Paresthesia Report client about the
loose stools adverse as
or diarrhea
active benign  Reactions
Dream effects of the drug
acid secretion. these may indicate
gastric ulcer abnormalities
 Phlebitis at IV site pseudomembranous colitis.
 Rash  Report severe
Tell patient toheadache,
report any adverse
 Urticaria worsening
reactions of symptoms, fever,
 Pruritus  chillss severetodiarrhea
Tell patient report discomfort
 Dry skin at IV site
 Tell patientthat
Document to report signsgiven
drug was and
 Diarrhea
symptoms of low magnesium
 Nausea
 DRUG STUDY

 Vomiting  Dosage adjustment maybe

 Abdominal pain necessary in Asians and patients
 Constipation with hepatic impairement
 Cough
 Drug increases it’s own
bioavailability with repeated
doses. Drug is unstable in gastric
acid; less drug is lost to hydrolysis
because drug increases gastric pH.

 Document that drug was given

NAME OF CLASSIFICATION SPECIFIC INDICATION CONTRAINDICATION ADVERSE NURSING RESPONSIBILITIES

DRUG ACTION EFFECTS
Metronidazole Therapeutic Class: Direct-acting  To prevent Contraindicate in patients  Headache  Consider the 12 Rights of
50mg IVTT q 8hrs Antiprotozoals trichomonicide post-operative hypersensitive to drug or  Seizures administering medication
Pharmacological and amebicide that infection other nitroimidazoles.  Fever
Class: works inside and  To prevent  Vertigo  Observe patient for edema
Nitroimidazoles outside of the bacterial Use cautiously in patients  Iritability
intestine. It’s infection with history of retinal or  Edema  Monitor LFT results carefully.
thought to enter visual field changes.
 Rhinitis
the cells of  Don’t give IV push
 Sinusitis
mnicroorganisms Use cautiously in patients
that contain nitro who take hepatotoxic drugs  Pharyngitis
 Don’t refrigerate neutralized
reductase, forming or have hepatic disease or  Nausea
 Abdominal pain diluted solution precipitation may
unstable alcoholism. occur
compounds that  Stomatitis
 DRUG STUDY

bind to DNA and  Anorexia  Record number and chracter of

inhibit synthesis,  Diarrhea stools when drug is used
causing cell death.  Drymouth
 Darkened urine  Tell patient to avoid alcohol and
 Polyuria alcohol containing drugs during
 Dysuria and for atleast 3 days after
 Transient joint treatment course
pains
 URTI  Tell patient to report to prescriber
 Rash immediately any neurologic
symptoms such as seizures, and
 General pruritus
peripheral neuropathy

 Document that drug was given

DRUG STUDY
 DRUG STUDY

NAME OF GENERAL SPECIFIC ACTION INDICATION CONTRAINDICATION ADVERSE NURSING RESPONSIBILITIES

DRUG ACTION EFFECTS
Paracetamol Analgesics; Thought to produce For pain Contraindicated in  Agitation  Consider the 12 Rights of
600mg IVTT q Para- amalgesia by patients hypersensitive to  Anxiety administering medication
6hrs x7 doses for aminophenol inhibiting drug IV form is  Fatigue
pain derivatives prostaglandin and contraindicated in  Headache  Monitor vital signs before
other substances that patients with severe  Insomnia and after administration.
sensitize pain hepatic impairement or  Abdominal pain
receptors. Drugs may severe active liver  Caution patient to contact
 Constipation
relieve fever throught disease. healthcare provider if signs
central action in the and symptoms of liver
hypothalamic heat- damage occur
regulating center
 Expect to reduce dosage for
patients with renal
dysfunction

 Document that drug was

given
.

NAME OF GENERAL SPECIFIC ACTION INDICATION CONTRAINDICATION ADVERSE NURSING RESPONSIBILITIES

DRUG ACTION EFFECTS
Tramadol 50mg Therapeutic Binds to opiate Managemet of Hypersensitivity to  Dizziness  Consider the 12 Rights of
IV q 12hrs PRN Class: receptors in the CNS pain in the tramadol, opiods, or any  Headache administering medication
for pain Analgesics causing inhibition of operation site component of the  Seizures  Reassess patient’s level of pain
Pharmacologica ascending pain formulation, opiod at least 30 mins after
 Asthenia
l Class: pathways, altering the dependent patients; acute administration.
 Sleep disorder  Monitor CV and respiratory
Synthetic perception of and intoxication with alcohol,
 DRUG STUDY

centrally active response to pain; also centrally acting  Vasodilation status. Withold dose and notify
analgesics inhibits the reuptake of analgesics, opiods, or  Visual disturbances prescriber if respirations are
norepinephrine and psychotropic drugs shallow or rate is below 12
 Constipation
serotonin, which also bpm.
 Nausea  Monitor bowel and bladder
modifies the ascending Use cautiously in patients  Vomiting
function. Monitor daily pattern
pain pathway with or at risk for acute  Abdominal pain of bowel activity, stool
abdominal conditions,
 Anorexia consistency.
renal or hepatic 
 Diarrhea Anticipate need for stimulant
impairement. laxative.
 Dry mouth
 Urine retention  For better analgesic effect, give
drug before onset of intense
 Hypertonia pain
 Diaphoresis  Monitor pulse, blood pressure,
 Pruritus renal/hepatic function. Assist
 Rash with ambulation if dizziness,
vertigo occurs.
 Monitor patient for drug
dependence similar to that of
codeine and thus has potential
for abuse.
 Withdrawal symptoms may
occur if drug is stopped
abruptly. Reduce dosage
gradually.
 Assess for clinical
improvement, record onset of
relief of pain.
 Document that drug was
given