(Science, Technology &society) : Pre-Final & Final
(Science, Technology &society) : Pre-Final & Final
Malilipot, Albay
GE 6
(Science, Technology &Society)
Pre-Final & Final
Prepared by:
BETTY B. DE ASIS
Content Standard:
Learning Outcomes:
Word Bank:
Renaissance, printing press, parachute, alchemy, newspaper,
circulation.
DISCUSSION:
Renaissance was a time of creativity and change in Europe. It was a rebirth of cultural and
intellectual pursuits after the stagnation of the Middle Ages. The Renaissance produced a golden
age with many achievements in art, literature, and science, but most importantly, it produced a
new concept of how people thought of themselves, each other, and the world around them.
The Renaissance was centered in Italy during the 1300’s before spreading throughout
Europe in the 1500 and 1600s. Great advances occurred in geography, astronomy, chemistry,
physics, mathematics, manufacturing, anatomy and engineering.
Science and Technology Development:
• The most important technological innovation of the time was the invention of the
printing press. This was introduced from China in the 1300s. By the 1400s movable type
was being used in Europe as Johann Gutenberg began printing the Bible in every
language. Soon millions of books were in circulation. This invention led to a higher
literacy rate among people, and helped with the spreading of Renaissance ideas.
a. Mining and metallurgy: blast furnace, finery forge, slitting mill, arquebus
and musket.
f. Newspaper is an offspring of the printing press from which the press derives
its name. The 16th century sees a rising demand for up-to-date information which
cannot be covered effectively by the circulating hand-written newssheets. For
“gaining time” from the slow copying process, Johann Carolus of Strassburg is
the first to publish his German-language Relation by using a printing press (1605)
Astronomy – Nicolaus Copernicus (1473-1543) Founded the theory of Heliocentric, that the
earth revolved around the sun. Sun is the center of the solar system.
The development of modern neurology began in the 16th century with Andreas Vesalius (1514-
1564). Who described the anatomy of the brain and other organs; In 1543, he published one of
the most famous publications in natural philosophy his anatomical book De fabrica (On the
Fabric of the Human Body. It was arguably the most important anatomical texts of the century, at
once criticizing the work of the ancients, principally Galen, offering new illustrations based on
first-hand observation and fresh dissections.
• Williams Harvey provided a refined and complete description of the circulatory system.
The most useful tomes in medicine, used both by students and expert physicians, were
Materia medicae and pharmacopoeia.
• Otto Brunfels (1530-1536) published Portraits of Living Plants, a botanical work that
employed freshly drawn illustrations from living plants, undermining the practice of
copying drawings from existing accounts.
DO YOU KNOW?
Leonardo da Vinci’s Vitruvian Man, an example of the blend of art and science
during the Renaissance. Leonardo Da Vinci studied anatomy, famous works include paintings
Mona Lisa and The Last Supper.
The inventions of mechanical printing press made possible the dissemination of knowledge to
wider population that led to a gradually more egalitarian society and able to dominate other
cultures.
Pre-final
ACTIVITY 1: IDENTIFICATION
1. (Ptolemy, Copernicus) Founded the theory Heliocentric, which states that the sun
is the center of the system.
2. He discovered that blood circulates through the body and started the science of
Physiology (William Harvey, Andreas Vesalius).
5. He described the anatomy of the brain as well as other organs of the body. He is
(William Harvey, Andreas Vesalius).
6. His publication in the Portraits of Living plants, describing each property and
characteristics (Theophrastus, Otto Brunfels).
7. He published a book about the revolution of the celestial bodies around the spheres in
1543 (Copernicus, Galen).
8. (Michelangelo, Leonardo da Vinci) is known as the great painter that did the
mural on the ceiling of the Sistine Chapel.
10. It is a period of rebirth after the fall of Roman empire, marked by great advances
in science and technology (Medieval period, Renaissance period).
LESSON 8
Content Standard:
The learners demonstrate an understanding of the development of Science and Technology
during Scientific Revolution.
Learning Outcomes:
Word Bank:
DISCUSSION
The scientific revolution was the emergence of modern science during the early modern
period, when developments in mathematics, physics, astronomy, biology and chemistry
transformed the views of society and nature. The scientific revolution began in Europe
towards the end of the Renaissance period and continued through the late 18th century,
influencing the intellectual social movement known as the Enlightenment.
Science and Technology Development:
3. Tycho Brahe (1544-1601), a Danish nobleman. He is known for his accurate and
comprehensive astronomical and planetary observations.
He was assisted by Johannes Kepler, where the latter used the information to develop his
own theories in Astronomy.
In November 1572, He discovered the “Tycho’s Star’ or the ‘Star of 1572’, a dramatic
supernova believed to appear in Cassiopeia constellation which became the talk of
Europe and the great Comet of 1577.
Proposed a system in which the sun and moon orbited the earth, while the other planets
orbited the sun. (Geo-Heliocentric theory or tychonic theory).
The crater Tycho on the moon is named after him, as in the crater Tycho Brahe on Mars.
9. Isaac Newton (1643-1727) built upon the work of Kepler and Galileo. He
showed that an inverse square law for gravity explained the elliptical orbits of the
planets, and advanced the law of universal gravitation; In his Principia, Newton
theorized his axiomatic three laws of motion.
10. Alexander Koyre, In the 20th century, introduced the term “Scientific
Revolution”, centering his analysis on Galileo, and the term was popularized by
Butterfield in his Origins of Modern Science.
14. Evangelista Torricelli (1607-1647) was best known for his invention of
the mercury barometer. The motivation for the invention was to improve on the suction
pumps that were used to raise water out of the mines.
DO YOU KNOW?
Newton’s first law of motion states that if the vector sum of the forces acting on an
object is zero, then the object will remain at rest or remain moving at constant
velocity. The Law of Inertia.
Newton’s second law relates to net force and acceleration. A net force on an object
will accelerate it---that is, change its velocity. The acceleration will be proportional to
the magnitude of the force and in the same direction as the force. The Law of
Acceleration.
Newton’s third law of motion states that an object experience a force because it is
interacting with other object. The force that object 1 exerts on object 2 must be of the
same magnitude but in the opposite as the force that object 2 exerts on object 1. The
law of interaction.
Newton’s law of Universe. The pull of the earth on objects at its surface is pull of
gravity.
LESSON 9
Content Standard:
The learners demonstrate an understanding of the Impact of Science and Technology on the
Society during the Industrial Revolution.
Learning Outcomes:
1. Describe the impact of science and technology on society during the Industrial revolution;
2. Recognize and appreciate the works of the different proponents of the Industrial Revolution
period.
Word Bank:
Atom, radioactive isotopes, mutations, genetics, biochemistry modern medicine, steam
engine, metallurgy, nucleosynthesis.
DISCUSSION:
In much of modern science the idea of progressive change, or evolution, has been of
fundamental importance. In addition to biological evolution, astronomers have been concerned
with stellar and galactic evolution, and astrophysicists and chemists with nucleosynthesis, or the
evolution of the chemical elements. Geologists have discovered that the continents are not static
entities but are also evolving; according to the theory of plate tectonics, some continents are
moving away from each other while others are moving closer together.
Physics in particular was shaken to the core around the turn of the century. The atom had
been presumed indestructible, but discoveries of X-rays (1895), radioactivity (1896), and the
electron (1897) could not be explained by the classical theories. The discovery of the atomic
nucleus (1911) and of numerous subatomic particles in addition to the electron opened up the
broad field of atomic and nuclear physics. Atoms were found to change not only by radioactive
decay but also by more dramatic processes—nuclear fission and fusion—with the release of
large amounts of energy.
• Albert Einstein—theory of relativity
• Radioactive isotopes have been used as tracers in complicated chemical and biochemical
reactions and have also found application in geological dating.
• Introduction of microscope by the Janssen team that paved way for the establishment of
the cell theory and study of minute things. Charles Darwin proposed the natural selection
as an explanation of evolution. Darwin’s complete theory is published in “On the Origin
of Species” in 1859. Gregor Mendel’s theory of Genetics, he observed and studied the
pattern of inheritance using a pea plant and developed the Mendelian Principles of
Heredity.
• Hugo de Vries around the turn of the century biological evolution came to be interpreted
in terms of mutations that result in a genetically species; the survival of a given species
was thus related to its ability to adapt to its environment through such mutations.
• The development of biochemistry and the recognition that most important biological
processes take place at the molecular level led to the rapid growth of the field of
molecular biology, with such fundamental results as the discovery of the structure of
deoxyribonucleic acid (DNA), the molecule carrying the genetic code.
• Modern medicine has profited from this explosion of knowledge in biology and
biochemistry, with new methods of treatment ranging from penicillin, insulin, and a vast
array of other drugs to pacemakers for weak hearts and implantation of artificial or
donated organs.
• In astronomy ever larger telescopes have assisted in the discovery that the sun is a rather
ordinary star in a huge collection of stars, the Milky Way, which itself is only one the
galaxies, that in general are expanding away from each other. Through space travel
astronomers were able to study and discover the nature of the universe beyond Earth. The
space age began with the launch of the first artificial satellites in 1957. A human first
went into space in 1961. Since then cosmonauts and astronauts have ventured into space
for further study of the universe.
• The study of remote objects, billions of light-years from the earth, has been carried out at
all wavelengths of electromagnetic radiation, with some of the most notable results being
made in radio astronomy, which has been used to map the Milky Way, study quasars,
pulsars, and other unusual objects, and detect relatively complex organic molecules
floating in space.
• The electronics industry, born in the early 20th century has advanced to the point where a
complex device, such as a computer, that once might have filled an entire room can now
be carried in an attaché case. The electronic computer has become one of the key tools of
modern industry. Electronics has also been fundamental in developing new
communications devices (radio, television, laser).
• A Watt steam engine, the steam engine, made of iron and fueled primarily by coal,
became widely used in Great Britain during the Industrial Revolution.
Metallurgy: A major change in the metal industries during the era of the Industrial Revolution
was the replacement of wood and other bio-fuels with coal. For a given amount of heat, coal
required much less labour to mine than cutting wood and converting it to charcoal, and coal
was more abundant than wood. The substitution of coke for charcoal greatly lowered the fuel
cost for pig iron and wrought iron production. Using coke also allowed larger blast furnaces,
resulting in economics of scale. The cast iron blowing cylinder was first used in 1760. It was
later improved by making it double acting, which allowed higher furnace temperatures.
James Watt and Matthew Boulton, had succeeded by 1778 in perfecting his steam
engine, which incorporated a series of radical improvements, notably the closing off of the
upper part of the cylinder thereby making the low pressure steam drive the top of the piston
instead of the atmosphere, use of a steam jacket and the celebrated separate steam condenser
chamber.
Machine Tools: created a demand for metal parts used in machinery. This led to the
development of several machine tools for cutting metal parts.
Chemicals: The large scale production of chemicals such as sulphuric acid by the lead chamber
process was invented by the Englishman John Roebuck. Sulphuric acid is used for pickling
(removing rust) iron and steel, and for bleaching cloth. Nicolas Leblanc, in 1791 introduced a
method for the production of sodium carbonate. Sodium carbonate had powder calcium
hypochlorite, revolutionized the bleaching processes in the textile industry by dramatically
reducing the time required for the traditional process then in use, which required repeated
exposure to the sun in bleach fields after soaking the textiles with alkali or sour milk.
Cement: In 1824 Joseph Aspdin, a British bricklayer turned builder, patented a chemical process
for making Portland cement which was an important advance in the building trades. This
process involves sintering a mixture of clay and limestone to about 1,400 °C, then grinding it
into a fine powder which is then mixed with water, sand and gravel to produce concrete.
Cement was used on a large scale in the construction.
Gas Lighting: Though others made a similar innovation elsewhere, the large-scale introduction
of this was the work of William Murdoch, an employee of Boulton and Watt, the Birmingham
steam engine pioneers. The process consisted of the large-scale gasification of coal in
furnaces, the purification of the gas (removal of Sulphur, ammonia, and heavy hydrocarbons),
and its storage and distribution. The first gas lighting utilities were established in London
between 1812 and 1820.
Glass Making: A new method of producing glass, known as the cylinder process, was developed
in Europe during the early 19th century. In 1832, this process was used by the Chance
Brothers to create sheet glass. They became the leading producers of window and plate glass.
This advancement allowed for larger panes of glass to be created without interruption, thus
freeing up the space planning in interiors as well as the fenestration of buildings.
Paper Machine: A machine for making a continuous sheet of paper on a loop of wire fabric was
patented in 1798 by Nicholas Louis Robert.
Agriculture: improved agricultural productivity freed up workers to work in other sectors of the
economy. Industrial technologies that affected farming included the seed drill, the Dutch
plough, which contained iron parts, and the threshing machine. Jethro Tull invented an
improved seed drill in 1701. It was a mechanical seeder which distributed seeds evenly across
a plot of land and planted them at the correct depth.
Food and Nutrition: food supply had been increasing and prices falling before the Industrial
Revolution due to better agricultural practices;
Housing: Living conditions during the Industrial Revolution varied from splendor for factory
owners to squalor for workers.
The Revolution Industrial also created a middle class of professionals, such as lawyers
and doctors, who lived in much better conditions.
Conditions improved over the course of the 19th century due to new public health acts
regulating things such as sewage, hygiene and home construction.
Clothing and Consumer Goods: Consumers benefited from falling prices for clothing and
household articles such as cast iron cooking utensils, and in the following decades, stoves for
cooking and space heating.
DO YOU KNOW?
A. The Hubble Space Telescope (HST) is an observatory that was launched into orbit by the
space shuttle Discovery in 1990. It escapes the distorting effects of the earth’s atmosphere by
orbiting about 610 km (about 380 mi) above the earth’s surface. The telescope was named
after American astronomer Edwin P. Hubble. It is the biggest space observatory that weighs
11 tons and is 13.1 m long and 4.3 m across. Has 2.4 wide mirror to gather light and images.
B. ROCKET was the first vehicle to leave the earth. Rocket is propelled upward by hot exhaust
gases streaming from nozzles at the tail. These gases are the result by burning a mixture of
liquid oxygen and fuel (liquid hydrogen) inside a combustion chamber. Carrying its own
oxygen supply enables rocket engine to function in the airless vacuum of space. The world’s
most powerful rocket is the Soviet Energeia. It weighs 2400 tons and has a thrust of 4000
tons, launched in May 1987.
LESSON 10
Content Standard:
The learners demonstrate an understanding of the development of Science and Technology in
the 20th century.
Learning Outcomes:
Word Bank:
Airplane, computers, optic fibers, internet, magnetic resonance imaging, gene therapy
DISCUSSION
There are heaps of developments of science and technology during the century and it keeps on
upgrading. The following are some of the remarkable invention that had major impact on
human being.
The Airplane
An Airplane or aeroplane was invented by the Wright brothers, Wilbur and Orville. It is
powered, fixed-wing aircraft that is propelled forward by thrust from a jet engine or propeller.
Their work leads them to make the first controlled, sustained, powered flights on December 17,
1903 in Kitty Hawk, North Carolina. On Jan. 1, 1914, the St. Petersburg- Tampa Airport Line
because the world’s first scheduled passenger airline service, operating between St. Petersburg
and Tampa, Florida. It was a short-lived undertaking but it paved the way for today’s daily
transcontinental flights.
The extensive uses of airplanes include recreation, transportation of goods and people,
military, and research. Commercial aviation is a massive industry involving the flying of tens of
thousands of passengers daily on airliners. Most airplanes are flown by a pilot on board the
aircraft, but some are designed to be remotely or computer-controlled.
Airplanes had a presence in all the major battles of World War II. The first jet aircraft
was the German Heinkel He 178 in 1939. The first jet airliner, the de Havilland Comet, was
introduced in 1952. The Boeing 707, the first widely successful commercial jet, was in
commercial service for more than 50 years, from 1958 to at least 2013.
Computers
The British built the Colossus and the Americans built the Electronic Numerical
Integrator Analyzer and Computer, or ENIAC between 1943 and 1945. Both Colossus and
ENIAC relied heavily on vacuum tubes, which can act as an electronic switch that can be turned
on or off much faster than mechanical switches. Computer systems using vacuum tubes are
considered the first generation of computers.
The first semiconductor transistor was invented in 1926, but only in 1947 was it
developed into a solid-state, reliable transistor for the use in computers. Similar to a vacuum
tube, a transistor controls the flow of electricity, but it was only a few millimeters in size and
generated little heat. Computer systems using transistors are considered the second generation of
computers.
In 1954, IBM introduced the first mass-produced computer. By 1958 it became possible
to combine several components, including transistors, and the circuitry connecting them on a
single piece of silicon. This was the first integrated circuit. Computer systems using integrated
circuits are considered the third generation of computers. Integrated circuits led to the computer
processors we use today.
Computers became quickly more powerful. By 1970 it became possible to squeeze all
the integrated circuits that are part of a single computer on a single chip called a microprocessor.
Computer systems using microprocessors are considered the fourth generation of computers.
In the early 1970s computers were still mostly used by larger corporations, government
agencies and universities. The first device that could be called a personal computer was
introduced in 1975.
The following are some of the highlighted development of computer:
• Steve Jobs and Steve Wozniak introduce Apple Computers on April Fool’s Day and roll
out the Apple I, the first computer with a single-circuit board in 1976.
• The first IBM personal computer, code named “Acorn”, was introduced. It uses
Microsoft’s MS-DOS operating system. It has an Intel chip, two floppy disks and an
optional color monitor in 1981.
• The first dot-com domain name was registered on March 15, years before the World
Wide Web would mark the formal beginning of Internet history in 1985.
• The Pentium microprocessor advances the use of graphics and music on PCs on 1993.
• PCs became gaming machines as “Command & Conquer”, Alone in the Dark 2”,
“Theme Park”, “Magic Carpet”, “Descent” and “Little Big Adventure” were among the
games hit the market in 1994.
• The term Wi-Fi becomes part of the computing language and users begin connecting to
the Internet without wires in 1999.
• Apples unveils the Mac OS X operating system, which provides protected memory
architecture and pre-emptive multi- tasking, among other benefits in 2001.
• Mozilla’s Firefox 1.0 challenges Microsoft’s Internet Explorer, the dominant Web
browser, Facebook, a social networking site, launches in 2004.
• Apple introduces the MacBook Pro, its first Intel-based, dual-core mobile computer, as
well as an Intel-based iMac. Nintendo’s Wii game console hits the market in 2006.
• The iPhone brings many computer functions to the smartphone in 2007.
• Google releases the Chromebook, a laptop that runs the Google Chrome OS in 2011.
• Facebook gains 1 billion users on October 4, 2012.
• The first reprogrammable quantum computer was created in 2016.
• The defense Advanced Research Projects Agency (DARPA) is developing a new
“Molecular Informatics” program that uses molecules as computers (2017).
Magnetic Resonance Imaging
Magnetic resonance imaging (MRI) is a non-invasive medical test that physicians use to
diagnose medical conditions. Magnetic resonance imaging (MRI) of the body uses a powerful
magnetic field, radio waves or pulses and a computer to produce detailed pictures of the inside of
your body such as organs, soft tissues, bone and virtually all other internal body structures. It
may be used to help diagnose the presence of certain disease and abnormalities or monitor
treatment for a variety of conditions within the body.
Physicians use an MRI examination to help diagnose or monitor treatment for conditions
such as: tumors of the chest, abdomen or pelvis; diseases of the liver such as cirrhosis, and
abnormalities of the bile ducts and pancreas; inflammatory bowel disease such as Crohn’s
disease and ulcerative colitis; heart problems, such as congenital heart disease, malformations of
the blood vessels and inflammation of the vessels (vasculitis); a fetus in the womb of a pregnant
woman.
The Internet
The Internet was the work of dozens of pioneering scientists, programmers and engineers
who each developed new features and technologies that eventually merged to become the
“information superhighway” we know today.
It started in early 1900 when Nikola Tesla toyed with the idea of a “world wireless
system”. Paul Otlet and Vannevar Bush conceived of mechanized, searchable storage systems of
books and media in the 1930s and 1940s. J.C.R. Licklider popularized the idea of an
“Intergalactic Network” of computers. These ground breaking ideas landed him a position as
director of the U.S. Department of Defense Advanced Research Projects Agency (ARPA), the
government agency responsible for creating a time-sharing network of computers known as
ARPANET, the precursor to today’s internet in 1960. Leonard Kleinrock invented the packet
switching, a method for effectively transmitting electronic data that would later become one of
the major building blocks of the Internet. ARPANET used packet switching to allow multiple
computers to communicate on a single network. Robert Kahn and Vinton Cerf in 1970,
developed Transmission Control Protocol and Internet Protocol, or TCP/IP, a communications
model that set standards for how data could be transmitted between multiple networks. In 1972,
Ray Tomlinson introduced network email. ARPANET adopted TCP/IP on January 1, 1983, and
from there researchers began to assemble the “network of networks” that became the modern
Internet. Tim Berners-Lee invented the World Wide Web in 1990. The web served as the most
common means of accessing data online in the form of websites and hyperlinks. The web helped
popularize the Internet among the public, and served as a crucial step in developing the vast
trove of information that most of us now access on a daily basis.
During the 1980s, the National Science Foundation started to build a nationwide computer
network that included its own supercomputers, called NSFNET. ARPANET had grown well
beyond the needs of the Development of Defense, and so the NSF took control of the “civilian
nodes”. In 1990, ARPANET was officially decommissioned.
Ultimately, the NSF aimed to build a network that was independent of government funding. The
NSF lifted all restrictions on commercial use on its network in 1991 and in 1995, the Internet
was officially privatized. At the time, the Internet was 50,000 networks strong, spanned seven
continents, and reached into space.
Optical Fiber
In 1952, UK based physicist Narinder Singh Kapany invented the first actual fiber optical
cable based on John Tyndall’s experiments three decades earlier. Jun-ichi Nishizawa, a Japanese
scientist proposed the use of optical fibers for communications in 1963. Optical fiber was
successfully developed in 1970 by Corning Glass Works (Robert Maurer, Donald Keck, Peter
Schultz, and Frank Zimar), with attenuation low enough for communication purposes and at the
same time GaAs semiconductor lasers were developed that were compact and therefore suitable
for transmitting light through fiber optic cables for long distances. By the early 1990’s as the
Internet was becoming popularized in the public realm, fiber optic cables started to be laid
around the world with a major push to wire the world in order to provide communication
infrastructure.
Fiber optic is preferred over electrical cabling when high bandwidth, long distance, or
immunity to electromagnetic interference are required. Due to much lower attenuation and
interference, optical fiber has large advantages over existing copper wire in long-distance, high-
demand applications.
Primitive air-conditioning systems have existed since ancient times. Attempts to control
indoor temperatures began in ancient Rome, where wealthy citizens took advantage of the
remarkable aqueduct system to circulate cool water through the walls of their homes. The
emperor Elagabalus in the third century, built a mountain of snow, imported from the mountains
via donkey trains and put it in the garden next to his villa to keep cool during the summer, but
this was so costly and inefficient. Such luxuries disappeared during the Dark Ages, and large-
scale air-conditioning efforts didn’t resurface in the West.
In the intervening centuries, fans were the coolant of choice. Hand fans were used in
China as early as 3,000 years ago, and a second-century Chinese inventor has been credited with
building the first room-sized rotary fan. Architecture also played a major role in pre-modern
temperature control. In traditional Middle Eastern construction, windows faced away from the
sun, and larger buildings featured “wind towers” designed to catch and circulate the prevailing
breezes.
In late 19th-century American engineers pick up where the Romans had left off. In 1881,
a dying President James Garfield got a respite from Washington D.C.’s oppressive summer
swelter, thanks to an awkward device involving air blown through cotton sheets doused in ice
water.
Nikola Tesla’s development of alternating current motors made possible the invention
of oscillating fans in the early 20th century using electricity. And in 1902, a 25-year-old engineer
from New York named Willis Carrier invented the first modern air-conditioning system. The
mechanical unit, which sent air through water-cooled coils, was not aimed at human comfort,
however; it was designed to control humidity in the printing plant where he worked. In 1922, he
followed up with the unit’s size. For years afterward, people piled into air-conditioned movie
theaters on hot summer days, giving rise to the summer blockbuster.
Carrier’s innovation shaped 20th-century America. In the 1930s, air conditioning spread
to department stores, rail cars, and offices, sending workers’ summer productivity soaring. As
late as 1965, just 10 percent of U.S homes had it, according to the Carrier Corporation. By 2007,
cool air spread across the country. Many American’s are turning to their air conditioners to
combat the current heat wave. These artificial breezes are a relatively novel innovation.
Gene Therapy
Gene Therapy attempts to treat genetic diseases at the molecular level by correcting
what is wrong defective genes. The first gene therapy was approved in the European Union in
2012, after two decades of dashed expectations. This approval boosted the investment in
developing gene therapies.
The gene therapy is successful, if it could work by preventing a protein from doing
something that causes harm, restoring the normal function of a protein, giving proteins new
functions, or enhancing the existing functions of proteins.
Gene therapy relies on finding on dependable delivery system to carry to correct gene
to the affected cells. The gene must be delivered inside the target cells and work properly
without causing adverse effects. Delivering genes that will work correctly for the term is the
greatest challenge of gene therapy. Viruses are often used by researchers to deliver the correct
gene to cells. In gene therapy, the DNA for the desired gene is inserted into the genetic material
of the virus and deliver its new genetic material which contains the desired DNA. Fatty
molecules known as liposomes may also be used as can micropipettes, sometimes called “gene
guns” to insert genes into cells physically.
ADA: The First Therapy Trial. A four-year old girl became the first gene therapy
patient on September 14, 1990 at the NIH Clinical Center. She has adenosine deaminase (ADA)
deficiency, a genetic disease which leaves her defenseless against infections. White blood cells
were taken from her, and the normal genes for making adenosine deaminase were inserted into
them. The corrected cells were reinjected into her. Dr. W. French Anderson helped develop this
landmark clinical trial when he worked at the National Heart, Lung, and Blood Institute.
3D Metal Printing
3D Metal Printing is one of the advances in the technology that provide instant metal
fabrication. This innovation enables the ability to create large, intricate metal structures on
demand and therefore could revolutionize manufacturing. It gives the manufacturers the ability
to make a single or small number of metal parts much more cheaply than using existing mass-
production techniques.
Artificial Embryos
Artificial Embryos are made from stem cells alone without using egg or sperm
cells. It is a breakthrough that will open new possibilities for understanding how life comes into
existence-but clearly also raises vital ethical and even philosophical problems.
Synthetic human embryos would be a boon to scientists, letting them tease apart
events early in development. And since such embryos start with easily manipulated stem cells,
labs will be able to employ a full range of tools, such as gene editing, to investigate them as they
grow.
Pregnant women sometimes need to have cells of their fetus tested for
chromosomal defects such as Edwards Syndrome and Down Syndrome. These tests require an
acquisition of cells that are quite invasive for the unborn baby. The test brought risk of
miscarriage and increased stress for pregnant mothers. With medical advances, it is now possible
for doctors to test-cell free fetal DNA by using the mother’s blood. This advance has become
more widely used and accepted internationally in the past year.
Cancer Nano-therapy
Nano devices and technology are already in wide use, and as the years pass, the
technology are already in wide use, and as the years pass, the technology in pharmaceuticals and
medicine will only continue to improve. One of which is an emerging cancer treatment
technology that implements nanomaterials in a more aggressive method. For example,
researchers at Israel’s Bar-Ilan University have developed nanobots to target and deliver drugs to
defective cells, while leaving healthy ones unharmed.
The 25-35 nm devices are made from single strands of DNA folded into a
desired shape- for instance, a clamshell-shaped package that protects a drug while on route to the
desired site but opens up to release it upon arrival.
Magnetic resonance imaging (MRI) is a non-invasive medical test that physicians use
to diagnose medical conditions. MR imaging of the body is performed to evaluate; organs of the
chest and abdomen- including the heart, livre, biliary tract, kidneys, spleen, bowel, pancreas, and
adrenal glands; pelvic organs including the bladder and the reproductive organs such as the
uterus and ovaries in females and the prostate gland in males, blood vessels and lymph nodes.
The laboratories of Drs. W. French Anderson and Michael Blaese in the National
Heart, Lung, and Blood Institute and the National Cancer Institute worked together to show that
cells from patients with ADA deficiency can be corrected in tissues culture. They used a
retrovirus to carry the correct human ADA gene to the cells of a four-year old girl and a nine-
year old girl with ADA deficiency. Each girl was given repeated treatments over a period of two
years. The nine-year old girl drew several pictures of her treatment—here she is receiving an
infusion of her own corrected cells. The two original ADA patients attend school and are leading
normal lives.
UNIT 3
FINAL
LESSON 1
Climate Change
Content Standard:
The learners demonstrate an understanding of the meaning, causes and effects of climate
change.
Learning Outcomes:
Word Bank:
Climate change, global warming, greenhouse gases, greenhouse effect
Discussion
The Earth’s climate has changed throughout history. Just in the last 650,000 years there
have been seven cycles of glacial advance and retreat, with the abrupt end of the last ice age
about 7,000 years ago marking the beginning of the modern climate era—and of human
civilization.
Earth is a very special planet- it orbits close enough to the sun to receive a lot of energy,
but far enough away not to be scorched. To help keep these conditions constant, our planet is
wrapped in a layer of greenhouse gases. This layer acts like a blanket, keeping the earth warm
and shielding it from the cold of universe.
CLIMATE CHANGE is a change in the statistical distribution of weather patterns when that
change lasts for an extended period of time (i.e. decades to millions of years) Global climate
change has already had observable effects on the environment. Glaciers have shrunk, ice on
rivers and lakes is breaking up earlier, plant and animal ranges have shifted and tress are
flowering sooner.
Effects that scientist had predicted in the past would result from global climate change are now
occurring: global temperature rise, shrinking ice sheets or loss of sea ice, accelerated sea level
rise and longer, more intense heatwaves, water acidification and extreme events.
Ninety- seven percent of climate scientist agree that climate-warming trends over the past
century are very likely due to human activities, and most of the leading scientist organization
worldwide have issued public statements enduring this position. One manifestation of climate
change is global warming.
Global warming refers to the increase in the average temperature of the earth’s near-surface air
and oceans in recent decades and its projected continuation. In common usage the term refers to
recent warming and implies a human influence. Most of the observed increase in globally
average temperatures since the mid-20th century is very likely due to the observed increase in
greenhouse gas concentrations,” which leads to warming of the surface and lower atmosphere by
increasing the greenhouse effect. Natural phenomena such as solar variation combined with
volcanos also produced greenhouse effect.
Human activities like mining, wrong practices in agriculture, illegal logging, burning of
fossil fuel, deforestation, too much car that emits carbon monoxide and carbon dioxide and
producing industrial waste are believe to be the sources of greenhouse gasses that in the long run
cause the climate change.
➢ Small amounts of heat trapping gases such as water vapor (H2O), carbon dioxide (CO2),
ozone (O3), methane CH4, nitrous oxide (N2O), and chlorofluorocarbon (CFCs) play a
key role in determining the earth’s average temperature and thus its climates.
➢ Together, these gases are known as greenhouse gases. They allow light, infrared
radiation, and some ultraviolet radiation from the sun to pass through the troposphere.
The earth’s surface then absorbs much of this solar energy and degrade it to longer wave
infrared radiation (that is heat), which then rises into the troposphere, some of this heat
escapes into space, some is absorbed by molecules of greenhouse gases, warming the air.
This natural trapping of heat in the troposphere is called greenhouse effect.
➢ The greenhouse effect first proposed by Swedish chemist Svante Arrhenius in 1896, has
been confirmed by numerous laboratory experiments and atmospheric measurements.
➢ Significance: the earth would be a cold and lifeless planet with an average surface
temperature of -18°C.
➢ Measured atmospheric levels of certain greenhouse gases – CO2, CFCs, methane, and
nitrous oxide- have risen substantially in recent decades- caused by human activities
burning fossil, fuels, agriculture, deforestation, and use of CFCs.
Carbon dioxide concentration- Carbon dioxide is responsible for 50-60% of the global
warming from greenhouse gases produced by human activities since pre-industrial times. The
main sources are fossil fuel burning: coal, oil and natural gas (75%) and land clearing and
burning (25%). Carbon dioxide (CO2, is nevertheless the main driver of the greenhouse effect.
Because of this the layer of greenhouse gas is getting thicker, which is in turn making the Earth
warmer.
Chlorofluorocarbon- contribute to global warming in the troposphere and deplete ozone in the
stratosphere. The main sources are leaking air conditioners and refrigerators, evaporation of
industrial solvents.
Methane concentration- Methane is produced when anaerobic bacteria break down organic
matter in moist places that lack oxygen. These areas include swamps and other natural wetlands,
rice paddies and landfills, intestinal tract of cattle, sheep, and termites.
Nitrous oxide concentration- Nitrous oxide can trap heat in the troposphere and deplete ozone
in the stratosphere. It is released from nylon production, burning of biomass and nitrogen
fertilizers in soil, livestock wastes.
What is the scientific consensus about future global warming and its effects?
➢ In 1992 Earth summit in Rio de Janeiro, 106 nations approved a Convention on Climate
Change, in which developed countries committed themselves to reducing their emission
of CO2 and other greenhouse gases.
➢ In December 1997 representatives of 160 nations met in Kyoto, Japan to negotiate a new
treaty to help slow global warming. The resulting treaty would require developed
countries to cut greenhouse emissions by the average of %.2% below 1990 levels
between 2008-2012.; allow emission trading, in which a country that beats its target goal
for reducing greenhouse gas emissions can sell its excess reductions to countries that
failed to meet their reduction goals; allow forested countries to get a break in their quotas
because trees absorb carbon dioxide; allow penalties for countries that violate the treaty,
to be determined later.
DO YOU KNOW?
The Greenland and Antarctic ice sheets have decreased in mass. Greenland lost 150 to 250
cubic km of ice per year between 2002 and 2006, while Antarctica lost about 152 cubic km of ice
between 2002 and 2005.
Extreme events – The number of record of extreme temperature events has been increasing
since 1950. The U.S. has also witnessed increasing numbers of intense rainfall events. In the
Philippines intense typhoons occur that kill people and destruct agriculture and environment
land.
LESSON 2
Content Standard:
The learners demonstrate an understanding of the state of the environment and natural resources
management.
Learning Outcomes:
The students will be able to:
1. State the meaning and types of natural resources;
2. Recognize and describe the causes of natural resources exhaustion;
3. State possible solution to solve problem of natural resources exhaustion;
4. Describe the impact of lesser natural resources to the society.
Word Bank:
Natural resources, biotic resources, abiotic resources, renewable resources, non- renewable
resources.
DISCUSSION
Natural Resources are all that exists naturally on Earth. It includes sunlight, atmosphere
(air), water, land (includes all minerals), metal ores, oil and most forms of energy along with all
vegetation and animal life that naturally exist on earth. Some natural resources such as sunlight
and air can be found everywhere, and are known as ubiquitous resources. However, most
resources only occur in small sporadic areas, and are referred to as localized resources.
There are very few resources that are considered inexhaustible (will not run out)- these are
solar radiation, geothermal energy, and air (though access to clean air may not be). The vast
majority of resources are exhaustible, which means they have a finite quantity, and can be
depleted if managed improperly.
Renewability is a very popular topic and many natural resources can be categorized as either
renewable or non-renewable:
• Renewable resources can be replenished naturally. Some of these resources, like sunlight,
air, wind, geothermal heat, biomass, etc., are continuously available and their quantity is
not noticeably affected by human consumption. Renewable resources are an important
aspect of sustainability.
• Non-renewable resources or finite resources either form slowly or do not naturally form
in the environment. Minerals are the most common resource included in this category. A
good example of this are fossil fuels (Petroleum and natural gas), because their rate of
formation is extremely slow (potentially millions of years), meaning they are considered
non-renewable.
Though many renewable resources do not have such a rapid recovery rate, these resources are
susceptible to depletion by over-use. Resources from a human use perspective are classified as
renewable only so long as the rate of replenishment/ recovery exceeds that of the rate of
consumption.
“The conservation of natural resources is the fundamental problem. Unless we solve that
problem, it will avail us little to solve all others”. – Theodore Roosevelt
Deforestation – The destruction of rain forests is one of the critical causes of climate
change. Deforestation causes carbon dioxide to linger in the atmosphere. As carbon dioxide
accrues, it produces a layer in the atmosphere that traps radiation from the sun. It also means
habitat loss for some living things. Deforestation also affects the water cycle. It reduces the
content of water in the soil and groundwater as well as atmospheric moisture. Deforestation
reduces soil cohesion, so that erosion, flooding and landslides follow.
Climate change – leads to rise of the sea level, thereby losing some of land territory,
Increase in global temperature that warms the earth especially the oceans making it impossible
for some species to survive, the Greenland and Antarctic ice sheets have decreased in the mass
due to shrinking of ice sheets. Ninety-seven percent of climate scientists agree that climate-
warming trends over the past century are very likely due to human activities.
Pollution—is the presence of a substance in the environment that because of its chemical
composition or quantity prevents the functioning of natural processes and produces undesirable
environmental and health effects. Pollutant is any material that causes the pollution coming from:
by product of essential activities such as transportation, factory; basic biological function-
excreting wastes and non-biodegradable wastes such as plastics, cans, organic chemicals, etc.
Reuse – Instead of buying everything new, reuse things as much as you can. This will not only
reduce waste but also save you money.
Repurpose – Don’t throw away things you’re no longer using; repurpose them into
something useful or beautiful. Worst case scenario, donate used items to a charity or thrift store
for someone else.
Rot – Compost as many things as you can instead of throwing it in the garbage. Composting is
a great way to renew the Earth, help reduce waste and maybe even help your garden.
Repair – When something breaks, don’t just immediately go out and buy a replacement. First
see if you can repair the item, or take it somewhere and have it repaired. It will not only save you
some money in the long run but also help reduce waste.
Recycle – On the topic of reducing waste, recycle whenever you can. Glass, cardboard, paper,
bottles, aluminum, batteries, electronics, scrap metal can be recycled into a usable thing such
décor, storage, or safety box.
Refill – Disposable items like cups, paper plates, paper napkins and bottles might be
convenient, but they’re terrible for the environment. Try using something that can be washed or
refilled more than once whenever you can.
Reduce – Downsize and simplify your home to reduce waste and excess. Living simply can
really help you can gain an appreciation for the little things, reduce your bills and help the
environment by having less waste.
Refuse – Whenever possible, refuse to buy over-package and single-use items or items that
are not organic. Change your daily habits and eating habits, lessen extravagant expenses of
material thing and food. Spend your money worthy. Try shopping at farmer’s markets instead of
the supermarket and pay attention to what you put in the shopping cart.
DO YOU KNOW?
Wind is just moving air created as the sun heats the Earth’s surface. As long as the sun
shining, the wind remains an infinite, renewable resource. Wind power is clean energy because
wind turbines do not produce any emissions. The windmill harnessed the wind’s energy turning
wind into electricity.
Solar panel, the sun has produced energy in the form of heat and light since the Earth formed.
Solar energy systems do not produce emissions and are often not harmful to the environment.
Thermal solar energy can heat water or buildings. Photovoltaic devices, or solar cells, directly
convert solar energy into electricity. Individual solar cells grouped into panels range from small
applications that charge calculator and watch batteries, to large systems that power residential
dwellings.
LESSON 3
FOOD INSECURITY
Content Standard:
The learners demonstrate an understanding of the meaning of Food Insecurity and its
application to the society.
Learning Outcomes:
The students will be able to:
1. State the meaning of Food Insecurity;
2. Describe the infiltration of Food insecurity to health of individual;
3. Identify the impact of food insecurity to health of individual;
4. Understand the importance and implications of food insecurity in the development of
science and technology.
Word Bank: Food Insecurity, hunger, malnutrition, poverty, food utilization, food security.
DISCUSSION
Physical AVAILABILITY of food – Food availability addresses the “supply side” of food
security and is determined by the level of food production, stock levels and net trade.
Economics and physical ACCESS to food – An adequate supply of food at the national or
international level does not in itself guarantee household level food security. Concerns about
insufficient food access have resulted in a greater policy focus on incomes, expenditure, markets
and prices in achieving food security objectives.
Food UTILIZATION – Utilization is a commonly understood as the way the body makes
the most of various nutrients in the food. Sufficient energy and nutrient intake by individuals is
the result of good care and feeding practices, food preparation, diversity of the diet and intra-
household distribution of food. Combined with good biological utilization of food consumed,
this determines the nutritional status of individuals.
STABILITY – of the other three dimensions over time- Even if your food intake is adequate
today, you are still considered to be food insecure if you have inadequate access to food on a
periodic basis, risking a deterioration of your nutritional status. Adverse weather conditions,
political instability, or economic factors (unemployment, rising food prices) may have an impact
on your food security status.
B. Food Insecurity in the United States and Its Impact to the society.
➢ It refers to the social and economic problem of lack of food due to resource not
voluntary fasting or dieting, or because of illness, or for other reasons as stated
by the Americans. This definition was supported by the ethnographic research
conducted by many researchers. Food insecurity is experienced when there is:
• Uncertainty – This usually happens whenever the ability to acquire
suitable foods in freely satisfactory ways is limited or future availability
and access of food in unsure.
• Insufficiency - This usually happens whenever there is a perception of
malnutrition, which is a disorder due to insufficient intake of nutrients to
meet necessary body cells requirements for a healthy living. Normally to
live a healthy life and become productive, it is a recommended that each
person must consume 2,200 calories each day.
DO YOU KNOW?
As of October 12,2017 according to the Global Hunger Index detailed that the Central
African Republic rests the top of the list as the hungriest country in the world because of some
reasons like instability, ethnic violence, and conflict that disrupt food production and displacing
more than half of its population to hunger.
LESSON 4
Medical Ethics
DISCUSSION
The following below are the categorization of beliefs, teaching, and instructions
of taught principles as in the essence of trust system that must be possessed by the medical
professional. Take note to grasp confidentiality in taking/ applying doctrines, because it is
traditionally applied to conversations between doctors and patients.
When two medical doctrines are in conflict, it will definitely result to ethical
dilemma or crisis. Sometimes when conflict cannot result to a good solution, a dilemma in
medical ethics will surely exist and even in the values of the medical community. Conflict can
also arise between health care providers or among a patient’s family members when they cannot
agree. Examples are the principles of autonomy versus beneficence like when patients refuse to
blood transfusion considering it will save life but against their religion.
DO YOU KNOW?
The late Mr. Alan Billis became the first man mummified in the style of the
ancient Egyptians for at least 3,000 years ago. Mr. Alan Billis was a taxi driver in Torquay,
England who loved documentaries and history. He volunteered himself to be mummified to the
experts namely; Professor Vanezis, Dr. Buckley, Dr. Fletcher and Maxine Coe.
Final Exam:
_____1. Which of the following is referred to as a system of moral principles that apply values to
the practice of clinical medicine and in scientific research?
_____2. Who among the following English authors and physicians below first termed the
Medical Ethics dating in 1803 and relying heavily on his words?
_____3. What century was the first Code of Medical Ethics published? It was also during the
reign of king Theodoric the great.
_____4. What year did the American Medical Association first adopt its code of ethics as
being based upon the word of Thomas Percival?
A. 1847 C. 2019
B. 1941 D. 1521
_____5. What must be practiced by medical professionals in applying doctrines, as in the essence
of trust system?
A. Confidentially
B. Discretion
C. Privacy
D. All of the above
_____6. What doctrine must a patient apply when he/she is refusing any kind of medical
treatment?
_____7. Portia is in terminal stage of cervical cancer. She is currently undergoing treatment of
radiation and chemotherapy and despite this invasive procedure her physician still
recommended pain reliever every time that she feels discomfort due to pain. What
doctrine did the physician apply?
A. Non-maleficence
B. Double effect
C. Autonomy
D. Beneficence
_____8. Referring to the latter situation, Portia was also confined in the East Avenue Medical
Center. During her confinement in the said hospital, there was a congestion of patients
to the extent that Portia is occupying the corridor of the emergency room. One time
Portia told his brother to call the attention of the nurse because she was feeling pain in
her right hand due to an intravenous insertion, but the nurse demonstrated arrogance that
she did not observe sterility in replacing Portia’s Intravenous port. On the above cited
incident what doctrine has the nurse violated?
A. Non-maleficence
B. Beneficence
C. Justice
D. All of the above
_____9. Still on the latter situation, Portia died battling her terminal stage cervical cancer at the
age of 29. Her type of cancer is an example of communicable disease thru early
exposure to sexual activities and in having different partners. Whatever is the reason
why Portia got her disease, what medical doctrines must apply not only to Portia but
also to people who suffer similar diseases?
_____10. The following below are a result of medical doctrines that are in conflict and have no
good solutions, except?
A. Quarrel
B. Emergency
C. Dilemma
D. Affection
ESSAY:
2. What are some examples of notable human successes in the field of medical
ethics?
3. What are some of the notable human failures in the field of medical ethics?
Good luck!
God bless you all.