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Zarina Barotova

James Johnson

ENG 1201.1V0

July 19, 2021

Efficacy and Disadvantages of COVID-19 Vaccine

A number of important factors played a decisive role in the human population in the

mechanism of transmission of COVID-19 (Coronavirus Disease 2019). These factors include

undiagnosed cases, asymptomatic cases, and multiple non-pharmaceutical interventions. Because

COVID-19 is spreading rapidly around the world, understanding the importance of these factors

is crucial in determining whether COVID-19 will be eradicated or preserved among the

population. So, in this study, we created a new mathematical model to predict the prevalence of

COVID-19 taking these factors into account. Why should COVID-19 vaccination not be

mandatory? How may it affect human health? COVID-19 immunization should not be required;

rather, it should be optional for healthcare workers and other professionals.

The 2019 coronavirus disease (COVID-19) vaccine will prevent you from becoming ill

with COVID-19 or becoming seriously ill or dying due to COVID-19. Certain types of vaccines

have at the moment. But how do different COVID-19 vaccines work? Each COVID-19 vaccine

causes the immune system to produce antibodies to fight COVID-19. COVID-19 vaccines use a

spike-like structure called C protein on the surface of the COVID-19 virus. The C protein helps

the COVID-19 virus enter your cells and initiate infection. The first type of vaccine is Messenger

RNA (mRNA) vaccine. This type of vaccine uses genetically managed mRNA to give directions

on the production of C protein located on the surface of the COVID-19 virus in your cells. After
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immunization, your immune cells form S protein fragments and start to dispense them on cell

exteriors.

The production of many vaccines against the SARS-CoV-2 virus, which is the cause of the

2019 coronavirus disease (COVID-19), is unprecedented and has made tremendous strides in the

year since the epidemic. The effectiveness of many developed vaccines has exceeded

expectations, and there are high hopes that an epidemic will soon be a thing of the past. Still,

there are a few problems. Vaccination in developed countries is incomplete and almost

non-existent in many developing countries, meaning it can take several years for herds

worldwide to gain immunity to the virus. Thus, hesitation in the vaccine is growing, especially in

young people who usually cope well with COVID-19, with minimal or no symptoms. In

addition, it is well established that COVID-19 vaccines can have significant side effects; indeed,

fear of these side effects may lead to SARS-CoV-2 infection in some populations.

The widespread adoption of the COVID-19 vaccine by the public is critical to effectively

halting the spread of the virus. Therefore, this study focuses on factors that differentiate those

undiagnosed from those who want to receive the prospective COVID-19 vaccine or those who do

not. Most importantly, the results of a recent COVID vaccine have not been determined. Those

who collected data on non-decision-makers [11] also did not consider this group to be the subject

of analysis. Those who are currently undecided are critical to their numbers and an effective

COVID-19 vaccination program locally and internationally. This study examined the

acceptability of the COVID-19 vaccine among national samples of elderly Australian adults and

focused on those who were unsure about whether or not to receive the COVID-19 vaccine.

Denis McDonough, Secretary of the Department of Veterans Affairs in Washington

declared that COVID-19 vaccines will be compulsory for medical staff, physicians, dentists,
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pediatricians, optometrists, registered nurses, physician assistants, extended dental assistants, and

chiropractors on July 26. Specific medical organizations, such as the American Hospital

Association, America’s Essential Hospitals, and a Multisociety group of the leading Infectious

Disease Societies, supported the department's decision. In addition, the American Medical

Association, the American Nurses Association, the American College of Physicians, the

American Academy of Pediatrics, the American Medical Colleges Association, and the National

Association for Home Care and Hospice have approved the COVID-19 vaccine for health care

workers.

There is currently no effective treatment for COVID-19. However, according to recent

reports, a single dose of Oxford-AstraZeneca or Pfizer-BioNTech vaccine provides high levels of

protection against COVID-19 symptoms, serious illness. It reduces the need for hospitalization

by 80%, including mortality. disease. [2] These findings add to the evidence that vaccines work

to reduce infections and save lives.

Work Cited

Aldila, Dipo, et al. "Impact of early detection and vaccination strategy in COVID-19 eradication

program in Jakarta, Indonesia." BMC Research Notes, vol. 14, no. 1, 2021, p. NA. Gale In

Context: Opposing Viewpoints,

link.gale.com/apps/doc/A658549580/OVIC?u=dayt30401&sid=bookmark-OVIC&xid=b9f6f60e

Attwell, Katie, et al. "Converting the maybes: Crucial for a successful COVID-19 vaccination

strategy." PLoS ONE, vol. 16, no. 1, 2021, p. e0245907. Gale In Context: Opposing Viewpoints,

link.gale.com/apps/doc/A649173906/OVIC?u=dayt30401&sid=bookmark-OVIC&xid=389d889

Iyengar, Karthikeyan P., et al. “Should COVID-19 Vaccination Be Made Mandatory?” Lung

India, vol. 38, no. 4, July 2021, pp. 379–381. EBSCOhost,

doi:10.4103/lungindia.lungindia_181_21.

Jonathan Sprent and Cecile King, ’’ COVID-19 vaccine side effects: The positives about feeling

bad’’ Science Immunology 22 Jun 2021,

https://immunology.sciencemag.org/content/6/60/eabj9256

Robert H. Shmerling, MD ’’COVID-19 vaccines: Safety, side effects –– and coincidence,’’

April 24, 2021

https://www.health.harvard.edu/blog/covid-19-vaccines-safety-side-effects-and-coincidence-202

1020821906
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VA » Office of Public and Intergovernmental Affairs » News Releases July 26, 2021,

https://www.va.gov/opa/pressrel/pressrelease.cfm?id=5696