An IUFD is fetal death that occurs after 24 weeks of gestation but before the onset of labor. It complicates about 1% of pregnancies. Causes include maternal conditions like APL syndrome, diabetes, infections, and placental issues. Fetal causes include genetic anomalies, birth defects, and hydrops. Management involves either waiting 2-3 weeks for spontaneous labor or inducing labor medically if there are risks like infection or DIC. The follow up includes determining the cause of death and managing future pregnancies as high risk.
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IUD
An IUFD is fetal death that occurs after 24 weeks of gestation but before the onset of labor. It complicates about 1% of pregnancies. Causes include maternal conditions like APL syndrome, diabetes, infections, and placental issues. Fetal causes include genetic anomalies, birth defects, and hydrops. Management involves either waiting 2-3 weeks for spontaneous labor or inducing labor medically if there are risks like infection or DIC. The follow up includes determining the cause of death and managing future pregnancies as high risk.
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IUFD
Definition: is fetal death after 24 weeks’ gestation but
before the onset of labour It complicates about 1% of pregnancies Diagnosis -Absence of uterine growth -Loss of fetal movement - Disappearance of the signs & symptoms of pregnancy - Fetal heart cannot be detected using Doppler device X-ray Spalding sign overlapping and disalgnment of the skull bones. Robert’s sign : the presence of gas in the fetal heart and great vessels. Acropad sign:( angulations of the fetal spine, exaggeration of fetal spinal curvature . U/S 100% accurate Dx(-ve fetal heart movement) Causes OF IUFD Maternal •APL syndrom: auto immune disease maternal Abs attack PhL of cell membrane of maternal Bd vessel & placenta. •DM: if poorly controlled . •HPT &PET :decrease placental Bd supply by spasim ,thrombosis & placental separation( AP). •Maternal infection; any disease causing fever & sepsis. TORCHS cause cong.abn & if severe FD. •Post term pregnancy •Drugs •Thrombophilia •Cyanotic heart disease Unexplained placental insufficiency occur in successive pregnancies ,the placenta is small but normal in other aspects. Causes OF IUFD Fetal causes •Chromosomal anomalies •Birth defects & genitic syndroms •Non immune hydrops • Haemolytic disease : e.g. RH iso-immunization ,If the fetal anaemia is sever enough, fetal hydropes ,HF and subsequent demise follows. Placental •Abruption •Cord accidents is more with abnormal lie or breech ,In these conditions true knot or constriction of the cord around a limb or neck will occur. •Twin to twin transfusion Syndrom •Chrioamnionitis Pathological anatomy: 1- The fetus is usually born in a macerated condition. Maceration occurs rapidly, and may be advanced within 24 hours of fetal death. 2- The whole body is softened and toneless. 3- The cranial bones are loosened and easily moveable on one another. 4- The liquor and the fluid in all the serous cavities contain blood pigments. Complications of IUFD: 1- Infection and chorioaminitis: when the membrane is ruptured. 2- Hypofibrinoginemia or DIC, when the fetus is dead more than 4 weeks. 3- PPH. 4- Psychological upset of the mother. Management - Conservative approch: About 80% of the a pt experience spontaneous onset of labour with in 2-3 weeks of fetal death.
- Active approch by induction of labour is indicated for:
1- An emotional burden on the mother. 2- Slide possibility of chorioaminitis. 3- 10% risk of DIC if death > 4 weeks. 4- Signs & symptoms of hypofilbrinogenemia.
F/U: to determine cause of death. Screening for diseases,
infections (TORCH), and chromosomal anomalies. Manage next pregnancies as high-risk The way of induction of labour is by : - Prostaglandin E2 vaginal suppositories or prostaglandin E1 analogs ( misoprostol ) oral rectal or vaginal. - Oxytocin infusion. - Intra-amniotic injection of hypertonic solution of urea. - Amniotomy is not done because of the risk of infection.