Standard Operating Procedure For Laboratory and Chemical Safety
Standard Operating Procedure For Laboratory and Chemical Safety
Chemical Safety
Review all Safety Data Sheets pertaining to each chemical under use in the laboratory. Proper chemical
labeling and storage is essential for a safe laboratory work environment. Inappropriate storage of
incompatible or unknown chemicals can lead to spontaneous fire and explosions with the associated release
of toxic gases. To minimize these hazards, chemicals in the laboratory must segregated properly. Storage and
handling procedures listed below are not intended to be all-inclusive but should serve instead to supplement
more specific procedures and recommendations obtained from container labels, Safety Data Sheets (SDS), and
other chemical reference material.
Chemical Identification
Manufacturer chemical labels must never be removed or defaced until the chemical is completely used. Once
a chemical is used, a permanent marker can then be used to completely obscure the manufacturer label. All
secondary chemical containers such as bottles, beakers, Erlenmeyer flasks, volumetric flasks, and vials should
all be labeled. Larger containers should have the full chemical name, the day’s date, and the initials of the user
of the container. Small containers should have either a number or a letter/character designation with a
referenced associated log that describes the contents of the smaller container. Groups of smaller containers
can be labeled as a group and stored together.
Safety Data Sheets
Safety Data Sheets (SDS) for all laboratory chemicals are required to be maintained in the laboratory or online.
Safety Data Sheets are available from chemical manufacturer’s websites. These can be accessed for free by
entering in the product code and /or manufacturers Lot number. The SDS for the exact chemical or mixture
provided by the manufacturer of the product must be available. The chemical identity and manufacturer
found on the label must match the chemical identity and manufacturer found on the SDS. All personnel must
know how to read and understand an SDS.
Chemical Storage
A defined storage place should be provided for each chemical/ chemical group and the chemical should be
returned to its defined place after every use.
Chemical containers must be in good condition before they are stored. Frequent inspection of chemical
containers can inhibit leakage or unwanted spills. The list of Hazard Groups for chemical grouping
distinguishes each chemical group to be stored with specific properties that similar to individual chemicals
within each group.
Hazard Groups
Flammable/Combustable Liquids
Inorganic Acids
Strong Bases
Water Reactives
Toxins/Poisons
Non-Toxics
Gases*- Inert/Flammable
Chemicals (including chemical waste) must be separated and stored according to their hazard group and
specific chemical incompatibilities. Reading the SDS of a specific chemical can lend insight on how to store a
specific chemical properly. Chemicals should be separated by distance. Physical barriers such as storage
cabinets and secondary containers should be used to prohibit contact of incompatible chemicals in the event
they are accidentally released or spilled. Liquids should not be stored above dry chemicals unless they are
stored in secondary containers. Storage of chemicals within hoods and on bench tops should be avoided.
Stored chemicals should not be exposed to heat or direct sunlight. Storage shelves and cabinets should be
secured to prevent tipping. Shelves should have a lip or doors to prevent chemicals from falling. Flammable
liquids in excess of 37.8 liters in each laboratory must be stored in an approved flammable storage cabinet.
Liquid chemicals should be stored below eye level to minimize spilling.