Review of Related Literature and Studies (Seguiran)
Review of Related Literature and Studies (Seguiran)
Review of Related Literature and Studies (Seguiran)
Ixora coccinea (I. coccinea) is a notable therapeutic plant generally circulated in East
Independents and is in jungles and differently in sub jungles at heights of 1300 m above ocean
level like Caribbean India and Sri Lanka. Root as tinctures is utilized as a society cure in loose
bowels and diarrhea. The pharmacognostical investigation of the previous reports uncovered that
the leaf concentrate of I. coccinea obtain antimicrobial, mitigating, against mitotic, astringent,
narcotic in hiccups, narcotic in sickness, narcotic in loss of hunger, antinociceptive and different
exercises. Likewise the blossoming part of I. coccinea have hostile to mutagenic movement with
wide running organic activity. Consequently in the current update the examination of wound
recuperating and antimicrobial investigations of I. coccinea root extricate against bacterial and
parasitic strains may prompted extending the I. coccinea as an adaptable medication in the
current herbal scenario. (Selvaraj et al. 2011)
The ethanolic extract showed significant (P<0.001) wound healing activity when compared to
standard drug NFZ with respect to normal control group. Amongst all, ethanolic extract showed
highly significant antibacterial activity against all bacterial strains used in this study when
compared to standard. The aqueous extract showed moderate significant inhibition against all
bacterial strains when compared to standard. All the extracts were shown negligible activity
against the fungal strains used in this study. (Selvaraj et al. 2011 p. 959 - 963)
Antimicrobial activity was detected in the 50% ethanolic extract of Ixora coccinea. The effective
inhibitory concentration of the extract against both the bacterial test organisms and the fungal
test organisms studied was 125 ug mL -1, beyond which the inhibitory activity declined and the
organisms started reviving from the effect of the antimicrobial principle. (Latha et al. 1995)
Study assessed the antimicrobial exercises of leaf concentrates of Ixora coccinea and Commelina
benghalensis against different Gram-negative (E. coli, P. aeruginosa, S. typhi) and Gram-positive
life forms (S. aureus). Hexane and chloroform extricates showed practically identical
antimicrobial action with the standard. Study evaluated leaf extract of various hued assortments
of Ixora coccinea against drug resistant pathogenic bacterial. An ethyl acetic acid derivation
concentrate of all assortments indicated critical fixation subordinate antibacterial movement,
particularly against Gram-negative microbes. (Santan, n.d)
Selvaraj N., Lakshamanan B., Mazumder P. M., Karuppasamy M., Jena S. S., & Pattnaik A. K.
coccinea root extract. Asian Pacific Journal of Tropical Medicine, vol.4(12), 959 – 963.
https://www.sciencedirect.com/science/article/pii/S1995764511602265?fbclid=IwAR3X6-
qz8r29xVA_OOaNq2ntQ5mTA_3UFfD9x-Ytqj3IbVXhfToUGVZZKyw
Latha P. G., Abraham T. K., & Pannikar K. R. (1995, April). Antimicrobial properties of ixora
https://pubmed.ncbi.nlm.nih.gov/22556712/