Renal 20nutrition 20web 1
Renal 20nutrition 20web 1
Renal 20nutrition 20web 1
Practice Guidelines
for Adults
June 2018
June 2018
i
TABLE OF CONTENT
ACKNOWLEDGEMENTS iv
ACRONYMS v
SCOPE AND PURPOSE vi
BACKGROUND AND MOTIVATIONS vii
SECTION A: ACUTE KIDNEY INJURY 1
1. DEFINITIONS 1
1.1 Classification of acute kidney injury (AKI) 1
1.1.1 Risk, injury, failure, loss, end stage renal disease (RIFLE) and acute
kidney injury network (AKIN) Classifications 2
2. NUTRITIONAL ASSESSMENT 2
2.1 Anthropometry 2
2.2 Biochemistry 2
2.3 Clinical 2
2.4 Diet history 2
2.5 Urinary analysis 2
2.6 Blood gases 2
3. NUTRITIONAL RECOMMENDATIONS 3
3.1 Summary 3
4. NUTRITIONAL INTERVENTION 4
5. MONITORING 6
5.1 Nutritional assessment monitoring and follow-up 6
5.2 Complications related to AKI 6
5.3 Medication commonly used in acute kidney injury and potential side effects 7
5.4 Patient education 8
SECTION B: CHRONIC KIDNEY DISEASE (INCLUDING RENAL TRANSPLANT) 9
1. DEFINITIONS 9
2. NUTRITIONAL ASSESSMENT 10
2.1 Anthropometry 10
2.1.1 Screening for overnutrition 10
2.1.2 Screening for undernutrition 10
2.2 Biochemistry 10
2.3 Clinical 11
2.4 Diet history 11
2.5 Urinary analysis 11
3. NUTRITIONAL RECOMMENDATIONS FOR CHRONIC KIDNEY DISEASE (CKD) 12
3.1 Nutritional Management of HIV/AIDS in CKD 12
4. NUTRITIONAL INTERVENTION 14
5. MONITORING 16
5.1 Nutritional assessment monitoring and follow-up 16
5.2 Complications related to dialysis treatment [hemodialysis (HD) and peritoneal (PD)] 17
5.3 Medication commonly used in chronic kidney disease and possible side effects 17
5.4 Patient education (chronic kidney disease) 18
5.4.1 Energy requirements 18
5.4.2 Protein requirements 19
ii
5.4.3 Sodium restriction 19
5.4.4 Fluid restriction 19
5.4.5 Potassium restriction 19
5.4.6 Phosphate restriction 20
5.4.7 Fibre and the gut microbiome 20
5.5 Transplant patient education 21
5.5.1 Early post transplant phase 21
5.5.2 Intermediate to late post transplant phase 21
5.5.3 Advice on discharge 21
6. REFERENCES 25
7. ANNEXURES 28
Annexure 1: Enteral Product Formulations 28
Annexure 2: Subjective Global Assessment (SGA.) 28
Annexure 3: South African Renal Exchange Lists Updated 2012 29
LIST OF TABLES
Table 1: RIFLE classification 1
Table 2: AKIN staging system 1
Table 3: Nutritional recommendations for acute kidney injury 3
Table 4: Monitoring checklist for the patient with AKI 6
Table 5: Complications related to hemodialysis and possible causes
thereof in the patient with AKI 6
Table 6: Medication commonly used in AKI and potential side effects 7
Table 7: Patient education (AKI) - general guideline 8
Table 8: Classification of overweight and obesity by body mass index (BMI),
waist circumference and associated disease risk 10
Table 9: Nutritional laboratory parameter outcome goals 11
Table 10: Nutritional recommendations for chronic kidney disease 12
Table 11: Nutritional recommendations for adults with diabetic nephropathy 14
Table 12: Monitoring checklist for the hospitalised patient with chronic kidney disease
(CKD) - conservative RRT (HD and CAPD) 16
Table 13: Monitoring checklist for the out-patient with chronic kidney disease (CKD)
- conservative renal replacement therapy (RRT) (HD and continuous
arterial peritoneal dialysis (CAPD) 16
Table14: Examples of the effects of HD and PD on nutrition 17
Table 15: Medication commonly used in renal disease and possible side effects 17
Table 16: Patient education (CKD) - general guide 23
Table 17: Patient education (transplant) - general guide 23
LIST OF FIGURES
Figure 1: AKI flow chart 1
Figure 2: Prognosis/classification of CKD 9
Figure 3: CKD flow chart 15
Figure 4: Patient education flow diagram 22
iii
ACKNOWLEDGEMENTS
The National Renal Nutrition Practice Guidelines for Adults will
assist in providing standardised and quality nutrition services to
patients attending public health institutions. Providing adequate
and appropriate nutrition in hospitals is imperative in building and
maintaining individuals’ nutritional status and thus decreasing
hospital length of stay.
The Directorate: Affordable Medicines and the National Essential Medicines List Committee, The South
African Society for Parenteral and Enteral Nutrition in South Africa, Association for Dietetics in South Africa
and provincial nutrition units also contributed to the development of these guidelines and we thank them for
their time and technical inputs.
MP MATSOSO
DIRECTOR GENERAL: HEALTH
DATE:
iv
ACRONYMS
ACE Angiotensin converting enzyme
AIDS Acquired Immunodeficiency Syndrome
AKI Acute kidney injury
AKIN Acute kidney injury network
ARF Acute renal failure
BEE Basal energy expenditure
BMI Body mass index
BP Blood pressure
BUN Blood urea nitrogen
CAPD Continuous ambulatory peritoneal dialysis
CKD Chronic kidney disease
CRP C-reactive protein
CRRT Continuous renal replacement therapy
DRI Dietary reference intake
DPI Dietary protein intake
EPO Erythropoietin
ESRD End-stage renal disease
GFR Glomerular filtration rate
HB Harris Benedict Equation for determining basal energy expenditure
HD Hemodialysis
ICU Intensive care unit
IHD Intermittent hemodialysis
IBW Ideal body weight
KDOQI Kidney disease outcome quality initiative
LDL Low density lipoproteins
NKF KDOQI National Kidney Foundation Kidney Disease Outcome Quality Initiative
PCR Protein catabolic rate
PD Peritoneal dialysis
pmp Per million population
PTH Parathyroid hormone
RIFLE Risk, injury, failure, loss, end stage renal disease
RRT Renal replacement therapy
SGA Subjective global assessment
TE Total energy
TG Triglycerides
TPN Total parenteral nutrition
UUN Urinary urea nitrogen (g/day)
VLDL Very low density lipoproteins
v
SCOPE AND PURPOSE
These guidelines aim to provide nutritional recommendations based on current evidence for best practice in
the management of acute and chronic renal disease. The guidelines are targeted at nutrition professionals
that play a role in the prevention and treatment of renal disease in adult patients attending public health
facilities for care.
vi
BACKGROUND AND MOTIVATION
Acute kidney injury (AKI) is increasingly prevalent in both developed and developing countries and associated
with severe morbidity and mortality. Worldwide, one in five adults experience AKI during a hospital episode of
care, which should raise concern and awareness amongst healthcare workers1, 2.
Efforts should focus on minimising the causes of AKI, providing guidance on preventive strategies and early
recognition and management. It is said that prevention is the key to avoid the heavy burden of mortality and
morbidity associated with AKI3, 4.
Chronic kidney disease (CKD) affects mainly adults aged between 20 and 50 years in Sub-Saharan Africa
and is primarily due to hypertension and glomerular diseases. Hypertension (especially in black patients) and
diabetes (especially in whites and Asians) are the main causes of chronic kidney disease in South Africa.
Human immunodeficiency virus (HIV) infection is an epidemic, however there is very little data available on
HIV-related glomerular disease. This is due to patients presenting late for treatment and usually already in
need of dialysis. The availability of renal replacement therapy (RRT) is limited due to high costs and shortage
of skilled employees. Dialysis rates are 4.5 per million population (pmp) for hemodialysis and 23 pmp for
continuous ambulatory peritoneal dialysis (CAPD) in South Africa. The transplant rate averages 4.7 pmp in
South Africa5. Thus, screening of high risk populations for CKD is a strategy that should be implemented,
directed at patients with hypertension, diabetes mellitus, proteinuria, HIV infection and a family history of
CKD6.
In addition, medical nutrition therapy plays a vital role in both the prevention and management of both
non-communicable and renal disease. Thus, a team approach is suggested with a registered dietitian taking
the key role in providing appropriate nutrition care.
vii
SECTION A: ACUTE KIDNEY INJURY
1. DEFINITIONS
• AKIN criteria
The AKIN criteria have similar urine output criteria to the RIFLE classification, but differ in the serum creatinine
levels as illustrated in Table 2.
* =Modified from RIFLE (Risk, Injury, Failure, Loss, and End-stage kidney disease) criteria. The staging system
proposed is a highly sensitive interim staging system and is based on recent data indicating that a small change
in serum creatinine influences outcome. Only one criterion (creatinine or urine output) has to be fulfilled to qualify
for a stage.
# = Given wide variation in indications and timing of initiation of RRT, individuals who receive RRT are considered to
have met the criteria for stage 3 irrespective of the stage they are in at the time of RRT.
1
2. NUTRITIONAL ASSESSMENT
Nutritional assessment of the AKI patient is comparable to the routine nutrition assessment of normal individuals.
2.1 Anthropometry
2.3 Clinical
• signs and symptoms of fluid overload
• abdominal distension and discomfort
• stools (frequency and consistency)
• temperature
• blood pressure (BP)
Nutritional support of AKI patients particularly demands an integrated and overall view on energy, protein, fluid, electrolyte
metabolism, and a careful and accurate assessment of nitrogen and electrolyte balances. 13 Nutritional support in AKI
should be started very early after injury. 13Nutritional support varies considerably between individual patients, depending
on the degree of renal failure, co-morbid illness and medical management. Therefore, there is no standard dietary
regimen that can be used for all patients. 14
2
3. NUTRITIONAL RECOMMENDATIONS
3.1 Summary
Note: Recommendations vary according to reference used. Clinical judgement remains important.
Glutamine Glutamine is contraindicated in patients with multi-organ failure and where GFR is less than 30 ml/min.
Note: In CRRT, approximately 0,2g amino acid is lost per litre of filtrate, resulting in a total loss of 10 to 15g amino acid (protein) per day.
Note: It is important to monitor serum TG and to reduce or stop fat /simple sugar intake, if TG exceeds 4.52 mmol/L (400mg/dL).
Note: Risks of vitamin D supplementation (>10 000 to 40000 IU per day) taken for extended periods, include hypercalcaemia, hypercalciuria and
acute kidney injury. Optimal vitamin D supplementation for critically ill patients with AKI has not yet been established.
3
4. NUTRITIONAL INTERVENTION
Prescribe an appropriate renal diet based on modality of treatment, patient’s tolerance and fluid restrictions. Patients
with poor oral intake should be supplemented accordingly or be considered for enteral feeding. Critically ill patients with
AKI would often require enteral feeding. Enteral feeding of AKI critically ill patients may be challenging due to impaired
gastrointestinal motility and decreased absorption of nutrients secondary to bowel oedema. AKI is a major risk factor
for gastrointestinal haemorrhage. Enteral feeding may potentially exert a protective effect in reducing the risk of stress
ulcers or bleeding.15
When sufficient enteral feeding cannot be achieved, the combination of enteral and parenteral feeding may be required
to achieve successful nutritional support. The two routes of feeding should be considered complementary, and not
mutually exclusive.18 Enteral nutrition is the preferential route in the first 24 to 48 hours upon intensive care unit (ICU)
admission, and if adequate enteral nutrition cannot be achieved between three and five days, parenteral nutrition should
be introduced.15
At the onset of AKI, when few patients can tolerate oral feedings because of vomiting and diarrhoea, intravenous
(IV) preparations can be used to reduce protein catabolism. Some patients can be managed with enteral feedings,
depending on the degree of severity of symptoms, but in most AKI patients, IV feedings e.g. total parenteral nutrition
(TPN) must be used. The preferred treatment is illustrated in Figure 1.
4
5
5. MONITORING
Table 4 summarises measurements and laboratory tests used to monitor the effectiveness of therapy for the patient with
AKI. The frequency of testing will vary on an individual basis or as indicated.
Table 5 presents complications related to treatment and possible causes thereof in the patient with AKI.
Table 5: Complications related to hemodialysis and possible causes thereof in the patient with AKI29
Complication Cause
Protein and electrolyte loss leads to, e.g.: Inadequate protein and or calorie intake due to anorexia and uraemia,
Malnutrition altered taste, metabolic acidosis, inflammation, and reduced dietary
Poor rehabilitation intake
Fatigue
Anaemia
Infection
Hypotension Taking anti-hypertensive medication before dialysis
Heart disease
Septicaemia
Anaemia
Dehydration
Anaphylaxis
Air embolism
Eating/drinking during dialysis
Dialyzer reaction
Muscle cramps Removal of large amounts of fluids; changes in electrolytes
Nausea and vomiting Hypotension
Uraemia
Disequilibrium syndrome
Headache Hypertension
Too much fluid removal
Disequilibrium syndrome
Chest pain Ischemia
Hypertension Fluid overload prior to dialysis.
Non-compliance with blood pressure medications patients not taking
medication
Anxiety
6
5.3 Medication commonly used in acute kidney injury and potential side effects
Listed in this section are the commonly prescribed renal specific medications used in AKI, similar to chronic kidney disease,
displaying their indication, action and side-effects limited to nutrition and gastrointestinal function. It includes various
diuretics, anti-hypertensives, phosphate binders (not routinely used) and certain immuno-suppressive medication, etc.
Table 6: Medication commonly used in AKI and Potential Side Effects30, 31,32,33
Medication Indication Action Nutritional side-effects
Furosemide Oedema, fluid overload Loop diuretic Urinary loss of potassium, zinc, magne-
sium, calcium, sodium
dehydration
Thiazide Diuretics Hypertension Potent diuretic, prevent re-absorption Nausea, anorexia, hyponatraemia,
of sodium, potassium, chloride hypokalaemia, hyperuricaemia, hyper-
glycaemia
Spirinolactone Hypertension, fluid overload Aldosterone antagonist, potassi- Hyperkalaemia, dry mouth, nausea,
um-sparing diuretic, which blocks vomiting, gastritis, diarrhoea
exchange of sodium with potassium
and hydrogen
Calcium Hyperphosphataemia, Calcium supplement and phosphate Constipation, increased Ca-P product,
hypocalcaemia binder. If used as a supplement, do hypercalcaemia, calcium citrate increas-
not use with food es aluminium absorption, nausea and
vomiting
Aluminium hydroxide sus- Hyperphosphataemia Binds the phosphorus from ingested Constipation, aluminium toxicity, in-
pension food in the gut (Ca-P complex), pre- crease thiamine requirements, impaired
venting absorption. iron and folate absorption
Take with meals while restricting
phosphate intake
Sevelamer Hydrochloride Hyperphosphataemia Non-calcium, non-aluminium phos- Increased calcium absorption if taken
phate binder, ionic and hydrogen with calcium, diarrhoea, nausea, vom-
bonding of phosphate iting, dyspepsia, peripheral oedema,
decrease LDL, increase HDL
Sodium polystyrene sul- Hyperkalaemia Sodium and potassium exchange in Sodium and fluid retention, diarrhoea,
fonate the gut; potassium containing resin is nausea and vomiting, constipation, hy-
excreted in the stool pokalaemia, hypocalcaemia, hypomag-
nesaemia
Angiotensin converting Hypertension, renoprotection, Inhibits the production of angiotensin Hyperkalemia
enzyme (ACE) inhibitors heart failure (vasoconstrictor)
Slows the degradation of bradykinin
(vasodilator)
Avoid natural liquorice
Beta blockers Hypertension Adrenergic inhibitor, blocks sympa- Abdominal discomfort, flatulence, mask-
thetic effects on heart and results in ing if insulin-induced hypoglycaemia,
reduced arterial pressure and cardiac lowering of HDL-cholesterol, increase
output total-cholesterol and triglycerides
Alpha Blocker Hypertension Adrenergic-receptor blocking norepi- Modest lowering of LDL-cholesterol,
nephrine action dryness of mouth
Corticosteroids (Predni- Immuno-suppressant used Anti-inflammatory, immunosuppres- Hypertension, sodium and fluid
sone, Methylprednisolone during kidney transplantation sion retention, increased appetite weight
and treatment of many kidney gain, diabetes mellitus, dyslipidaemia,
diseases hypokalemia, hypocalcemia, osteoporo-
sis, osteonecrosis, hypophosphataemia,
protein hypercatabolism , urinary losses
of zinc, potassium, calcium, vitamin C
and nitrogen, gastrointestinal ulceration,
impaired wound healing, pancreatitis,
impaired growth in children
Cyclophosphamide Used to treat auto-immune Interfere with DNA replication Nausea, vomiting, diarrhoea, mouth
disorders sores, syndrome of inappropriate ADH
7
5.4 Patient education
(For specific patient treatment e.g. fluid, potassium, sodium and protein refer to patient education in CKD)
Patient education is only applicable when the patient is discharged and is taking in food orally. The patient education
guidelines are summarised in Table 7.
8
SECTION B: CHRONIC KIDNEY DISEASE (INCLUDING RENAL TRANSPLANT)
1. DEFINITIONS
Acute glomerulonephritis: A group of diseases characterised by inflammation of the capillary loops of the glomerulus.
Azotemia: The accumulation in the blood of abnormal quantities of urea, uric acid, creatinine, and other nitrogenous
wastes.
Chronic kidney disease: Abnormalities of kidney structure or function, present for more than three months with
implications for health and CKD is classified based on cause, GFR category, and albuminuria category.35
End-stage renal disease (ESRD): A disease characterised by the kidney’s inability to excrete waste products, maintain
fluid and electrolyte balance and produce hormones.
Erythropoietin (EPO): A hormone secreted chiefly by the kidney in the adult and by the liver in the foetus, which acts
on stem cells of the bone marrow to stimulate red blood cell production.
Glomerular filtration rate (GFR): The quality of glomerular filtrate formed per unit in all nephrons of both kidneys.
Nephritic syndrome: The syndrome of haematuria, hypertension and mild loss of renal function that results from acute
inflammation of the capillary loops of the glomerulus.
Nephrotic syndrome: A condition resulting from loss of the glomerular barrier to protein; characterised by massive
oedema, proteinuria, hypoalbuminemia, hypercholesterolemia, hypercoagulability, and abnormal bone metabolism.
Uraemia: A clinical syndrome of malaise, weakness, nausea, vomiting, muscle cramps, itching, metallic mouth taste and
often neurological impairment, which is brought about by azotemia. 30
Figure 2. Prognosis of CKD by GFR and albuminuria category (adapted from KDIGO 2012)35
Green- low risk (if no other markers of kidney disease, no CKD); Yellow- moderately increased risk; Orange - high risk; Red - very high risk
9
2. NUTRITIONAL ASSESSMENT
The nutritional assessment of the CKD patient is comparable to a routine nutrition assessment of normal individuals, but
with some modifications.
The ABCD (anthropometry, biochemistry, clinical and dietary) approach should be used when doing a nutritional
assessment as discussed below.
In patients receiving renal replacement therapy, the focus should be placed on body composition rather than on weight
loss in isolation to reduce metabolic demands on the kidney and as a result delay progression of ESRD. Thus BMI
should not be used in isolation, but rather with other anthropometric indicators like waist circumference.
2.1 Anthropometry36
Table 8. Classification of overweight and obesity by BMI, waist circumference and associated disease risk38
2.2 Biochemistry
Selected nutrition-related laboratory parameters for haemodialysis and peritoneal dialysis are shown in Table
8, based on K/DOQI recommendations. 13
10
Table 9: Nutritional laboratory parameter outcome goals 32
Nutritional laboratory parameter Goal Outcome prevention focus
S-Sodium (mmol/L) 136-145 Fluid and blood pressure control
S-Potassium (mmol/L) 4.0-5.5 Cardiac arrhythmia and cardiac arrest
S-albumin g/L 35-52 Protein-energy malnutrition
S-Urea (mmol/L) 22-29 Protein intake
Malnutrition
Dialysis adequacy
Pre-dialyses S-creatinine (µmol/L) Pre ESKD 177-708 Malnutrition
Small patient on dialysis 708-1062
Large patient on dialysis 1328-1770
TCO2 (mmol/L) >22 Metabolic acidosis
Kt/V or urea reduction ratio >1.2 HD or >65% Dialysis adequacy
1.7 PD
S-Phosphate (mmol/L) 0.8-1.4 Soft tissue calcifications, bone disease
Maintain in the normal range Stages 3-5
0.78-1.42
S-Calcium (mmol/L) corrected 2.05-2.45 Soft tissue calcifications, bone disease
S-Calcium-phosphate product mmol2/L2 ≤5 or <4.4 Soft tissue calcifications , bone disease
PTH (ng/L) Stage 5: Hyperparathyroidism
2-9x normal range (normal range 1.5-7.6) Stage 3 -5
No optimal range
Transferrin saturation 20-50%
Serum Ferritin ( μg/L) 200-500
2.3 Clinical
Fluid overloading:
• oedema
• shortness of breath
• increased blood pressure
• oedematous gut, which could lead to irregular gut function
• swelling in legs and face
• need for oxygen
Uraemic symptoms:
• nausea, vomiting or dry retching
• anorexia
• taste changes
• bad smelling breath
• dizziness
• headaches
• irritable
• insomnia
• extreme exhaustion
• uraemic gut syndrome
Potassium symptoms:
• heart palpitations
• fainting
• heart attacks
Dietary intake assessment can be completed using traditional choices of diet recall, food diary, food frequency
questionnaires or food exchanges.
• glucose
• protein
• urea and creatinine
11
3. NUTRITIONAL RECOMMENDATIONS FOR CKD 42, 43,
Table 10 summarises the macro and micro nutrient recommendations for CKD
Table 10: Nutritional recommendations for chronic kidney disease20,22,33,42, 43, 44,45,46,47,48
Requirements Conservative (non-dialysed) Hemodialysis Peritoneal dialysis Transplant
Protein(g/kg/d) 0.6 - 0.75 1.2 1.2-1.3 Initial:
At least 50% HBV At least 50% HBV At least 50% HBV 1.3 – 2.0
Stage 1-3: 0.75 10-12g amino acid loss
Stage 4-5: 0.6-.75 per dialysis session 5-15g protein loss per
Maintenance:
Nephrosis: 0.8-1.0 / 0.8 plus day
0.8-1.0
1.2 (urine protein loss) Chronic rejection (non-dial-
ysed)
0.6-0.8
Energy(kcal/kg) Initial:
30-35 30-35
30-35 30-35 Includes energy from Maintenance:
dialysate 25-30
Maintain desirable body
weight
NOTE: This energy intake is needed to ensure a positive nitrogen balance. Obese patients requires <35 kcal /kg/d, while underweight patients
would require more than 35kcal/kg/d.
Use actual weight if falls within the 95th-115th percentile of standard weight or adjusted if actual body weight falls <95th percentile (underweight) or
> 115th percentile (overweight/obese)these ranges,
Carbohydrates (% TE) 50-60 of total energy 50-60 of total energy 50-60 of total energy 50-60 of total energy
(complex) (complex) (complex) (complex)
Includes carbohydrates
from dialysate (see sim-
ple estimate formula)
Fat (% TE) 25-35 of total energy 25-35 of total energy 25-35 of total energy 25-30 of total energy
Cholesterol (mg/d) <300 <300 <300 <300
S/P/M/ ratio (%) <7: ≤10: ≤10 <7: ≤10: ≤10 <7: ≤10: ≤10 <7: ≤10: ≤10
Fibre(g/d) 20-30 20-30 20-30 20-30
Fluid (ml/d) Usually unrestricted with Output PLUS Monitored, Unrestricted unless indicated
normal urine output 500-750 1500-2000
Output PLUS New guidelines PLUS
500-750 1000ml
NOTE: Interdialytic weight gain should ideally not exceed 2-2.5kg or 4-4.5% of the dry weight.
Minerals Conservative Hemodialysis Peritoneal dialysis Transplant
Sodium (mg/d) 1000-4000 ≤ 1L urine 2000-4000 2000-4000 2000-4000
(Individualise) ≤ 1L urine 2000 (Individualise) (Individualise)
(Individualise)
Potassium (mg/d) 2000-3000 / 40mg/kg 2000-3000 / 40mg/kg 2000-4000 Unrestricted; unless hyperka-
1500-2700 if hyperkalaemic laemia
Calcium (mg/d) <2000 (<1500mg/d from <2000 (<1500mg/d from <2000 (<1500mg/d from 1200-1500
binders) binders) binders)
NOTE: Dietary calcium intake, including a calcium-based phosphate binder, should not exceed 2000mg/day to reduce the risk of hypercalcaemia
and vascular calcifications.
Phosphate (mg/d) 800-1000 / 800-1000 / 800-1000 / DRI
10mg/kg / <17 mg/kg 10-15mg/g Protein
10-12mg/g Protein 10-15mg/g Protein P-binders
P-binders P-binders
Magnesium (mg/d) 200-300 200-300 200-300 DRI, supplement if decreased
levels
Iron (mg/d) 10-18 (Individualise) 10-18 (Individualise) 10-18 (Individualise) DRI, individualise supplemen-
tation
12
Requirements Conservative (non-dialysed) Hemodialysis Peritoneal dialysis Transplant
Zinc (mg/d) Individualise Individualise Individualise DRI
NOTE: Routine supplementation of Zinc, Selenium and Copper not recommended.
Thiamine (mg/d) 1.1-1.5 1.1-1.5 1.1-1.5 DRI
Riboflavin (mg/d) 1.8 1.1-1.3 1.1-1.3 DRI
Panthothenic acid 5 5 5 DRI
(mg/d)
Niacin (mg/d) 14-20 14-20 14-20 DRI
Pyridoxine (mg/d) 5 10 10 DRI
NOTE: Decreased levels of pyridoxine are associated with hyperhomocysteinaemia.
Vit B12 (μg/d) 2-3 2-3 2-3 DRI
Folate mg/d 1.0 1.0 1.0 DRI
NOTE: Vitamin B12 and Folate supplementation are required for normal erythropoiesis and an optimal response to the medications used to stimulate
erythropoiesis.
Vit C mg/d 60-100 60-100 60-100 DRI
NOTE: High doses of supplemented vitamin C of >200mg/day is not advised due to increased risk of oxalate deposition that may contribute to
vascular disease.
Vit A (μg/d) No supplementation No supplementation No supplementation DRI
NOTE: Vitamin A is known to accumulate during renal failure and therefore routine supplementation is not recommended during CKD.
Vit D (μg/d) Individualise Individualise Individualise DRI
NOTE: Consider Vitamin D supplementation for the treatment of osteomalacia and hyperparathyroidism.
Supplementation may be indicated.
Vitamin D: Individualise means we need to consider the patients calcium, phosphate and parathyroid hormone (PTH) levels, if need start at 0.25ug
of 25(OH)vitamin D and titrate upwards.
Vit E mg/d 0-15 (Individualise) 0-15 (Individualise) 0-15 (Individualise) DRI
NOTE: Vitamin E is known to accumulate during renal failure and therefore routine supplementation is not recommended during CKD. There is
controversy regarding the optimal vitamin E dose to be supplemented.
Vit K μg.d Individualise Individualise Individualise DRI
NOTE: The RDA for vitamin K is recommended except in cases with altered coagulant activity and long-term treatment with antibiotics.
Carbohydrates absorbed from the peritoneal dialysate should be taken into account when calculating the calorie
requirements. The ‘Simple Estimate Formulae’ can be used. 49, 50.
The Simple Estimate Formulae:
Estimate of calories absorbed from PD with 60% absorption rate50 (absorption rate ranges between 60-70%):
1.5% 1L = 15g X 3.4 = 51 X 60% = 31 kcal / L
2.5% 1 L = 25g X 3.4 = 85 X 60% = 51 kcal / L
4.25% 1L = 42.5g X 3.4 = 144.5 X 60% = 86.7 kcal / L
Concentration of dextrose absorbed27
Dialysate dextrose concentration Grams of dextrose/L kcal/L from dextrose kcal/L with CAPD (60%)*
1.50% 15g 51kcal 31kcal
2.50% 25g 85kcal 51kcal
4.25% 42.5g 144.5kcal 86.7kcal
*60% dextrose absorbed with CAPD
**each gram of dextrose = 3.4kcal
E.g. Energy/L x Total Volume
Note: In usual practice the dialysate bags are two litres in volume, used four times per day, giving eight litres in total per day.
13
Table 11: Nutritional recommendations for diabetic nephropathy45,51,52, 53,54,55,56
Requirements Conservative Hemodialysis Peritoneal dialysis
Protein (g/kg/d) 0.6-0.8 1.2 1.2-1.3
High biologic value protein % 50 (at least) 50 (at least) 50 (at least)
Energy (per day) H-Bakcal or 30-35 kcal/kg H-Bakcal or 30-35 kcal/kg H-Bakcal or 30-35 kcal/kg
Carbohydrates (%TE) 50-60 50-60 50-60
Fat (%TE) ≤30 ≤30 ≤30
Saturated fatty acids (% TE) ≤10 ≤10 ≤10
Polyunsaturated fatty acids (%TE) 6-8 6-8 6-8
Monounsaturated fatty acids (%TE) ≤15 ≤15 ≤15
Cholesterol (mg/day) <200 <200 <200
Fibre (g/d) 20-30 20-30 20-30
Fluid (ml/d) Output + (500-750) Output + (500-750) 1500-2000
Minerals Conservative Hemodialysis Peritoneal dialysis
Sodium (mg/d) <2300 2000-4000 2000-4000
Potassium (mg/d) 1500 - 2700 (restrict if raised) 2000-3000 2000-4000
Calcium (mg/d) <2000-2500 (including binder) <2000-2500 (including binder) <2000-2500 (including binder)
Phosphate (mg/d) 800-1000 / 10mg/kg / 800-1000 /<17 mg/kg 800-1000 / 10-15mg/g
10-12mg/g Prot P-binders 10-15mg/g Prot P-binders Prot P-binders
Iron (mg/d) 10-18 (Individualise supplemen- 10-18 (Individualise supplementation) 10-18 (Individualise
tation) supplementation)
Zinc (mg/d) 12-15 (male) 12-15 (male) 12-15 (male)
10-12 (female) 10-12 (female) 10-12 (female)
Selenium (μg/d) 55 55 55
NKF KDOQI: National Kidney Foundation Kidney Disease Outcome Quality Initiative
a
H-B: Harris Benedict Equation for determining Basal Energy Expenditure
TE: Total energy
All calculations are based on Ideal Body Weight
HBV: high biological value
4. NUTRITIONAL INTERVENTION
Since protein-energy malnutrition has shown to be one of the most important risk factors for increased morbidity and
mortality, every effort should be made to preserve optimal nutritional status in CKD patients. Figure 3 summarises the
nutritional interventions for patients with CKD.
Refer to Annexure 1 for enteral formulation guidelines.
14
15
5. MONITORING
#
Practices vary amongst hospitals but minimum requirements should be according to internal hospital protocols.
Table 12: Monitoring checklist for the hospitalised patient with chronic kidney disease (CKD) – conservative, RRT (HD and
CAPD) 27, 52
Parameter Frequency of assessment
Conservative RRT
Anthropometry
Weight Daily Daily
To monitor changes in fluid status. To monitor fluid, including pre- and post-dialysis weight.
*Biochemistry
Serum potassium, sodium Daily Daily
Serum urea and creatinine Daily Daily
Serum phosphorus, calcium and magnesium Weekly Weekly
Full blood count Weekly Weekly
Blood glucose Daily (if indicated) Daily (if indicated)
Serum albumin Weekly Weekly
Transferrin/RBS//Ferritin As needed As needed
CRP As needed As needed
Clinical
Signs and symptoms of oedema or dehydration Daily Daily
Stool output and consistency Daily Daily
Practices may vary amongst hospitals (guided by resources and costing) but minimum requirements should be according
to internal hospital protocols.
Table 13: Monitoring checklist for the out-patient with chronic kidney disease (CKD) – conservative, RRT (HD and CAPD) 27,
41, 57
16
Clinical
Signs and symptoms of oedema or dehydration 1 - 3 monthly Monthly
Stool output and consistency 1 - 3 monthly Monthly
Urine
Glucose 1 - 3 monthly As needed
Protein 1 - 3 monthly As needed
Practices may vary amongst hospitals (guided by resources and costing) but minimum requirements should be according
to internal hospital protocols.
Listed in this section are the commonly prescribed medication used in chronic kidney disease displaying their indication,
action and side-effects limited to nutrition and gastrointestinal function. It includes various diuretics, anti-hypertensive,
phosphate binders, immuno-suppressive medication etc.
Table 15: Medication commonly used in renal disease (CKD) and possible side effects30, 31,32,58
Medication Indication Action Nutritional side-effects
Furosemide Oedema, fluid overload Loop diuretic Urinary loss of potassium, zinc, magnesium,
calcium, sodium
Dehydration
Thiazide Diuretics Hypertension Powerful diuretic, prevent re-ab- Nausea, anorexia, hyponatraemia, hypokalae-
sorption of sodium, potassium, mia, hyperuricaemia, hyperglycaemia
chloride
Spirinolactone Hypertension, fluid over- Aldosterone antagonist, potassi- Hyperkalaemia, dry mouth, nausea, vomiting,
load um-sparing diuretic, which blocks gastritis, diarrhoea
exchange of sodium with potassium
and hydrogen
Calcium Hyperphosphataemia, Calcium supplement and phos- Constipation, increased Ca-P product, hyper-
hypocalcaemia phate binder. If used as a supple- calcaemia, calcium citrate increases aluminium
ment, do not use with food absorption, nausea and vomiting
Aluminium hydroxide Hyperphosphataemia Binds the phosphorus from ingest- Constipation, aluminium toxicity, increase
suspension ed food in the gut (Ca-P complex), thiamine requirements, impaired iron and folate
preventing absorption absorption
17
Active Vitamin D (calcitriol, Hypocalcaemia, secondary Increase calcium absorption Increased absorption of aluminium and phos-
alfacalcidol) hyperparathyroidism phate, hypercalcaemia
Erythropoietin Anaemia of chronic kidney Recombinant human erythropoietin; Increased appetite, iron, folate and vitamin B12
disease support erythropoiesis deficiency, increased blood pressure
Sodium polystyrene sul- Hyperkalaemia Sodium and potassium exchange in Sodium and fluid retention, diarrhoea, nausea
fonate the gut; potassium containing resin and vomiting, constipation, hypokalaemia,
is excreted in the stool hypocalcaemia, hypomagnesaemia
ACE inhibitors (Enalapril, Hypertension, renoprotec- Inhibits the production of angioten- Hyperkalaemia
Captopril) tion, heart failure sin (vasoconstrictor)
Slows the degradation of bradykinin
(vasodilator)
Avoid natural liquorice
Beta blockers Hypertension Adrenergic inhibitor, blocks sympa- Abdominal discomfort, flatulence, masking if
thetic effects on heart and results insulin-induced hypoglycaemia, lowering of
in reduced arterial pressure and HDL-cholesterol, increase total-cholesterol and
cardiac output triglycerides
Alpha blocker Hypertension Adrenergic-receptor blocking nor- Modest lowering of LDL-cholesterol, dryness
epinephrine action of mouth
Iron Iron deficiency Support erythropoiesis Constipation, nausea, vomiting, altered taste,
dark stools
Corticosteroids (Predni- Immuno-suppressant used Anti-inflammatory, immuno-sup- Hypertension, sodium and fluid retention,
sone, methylprednisolone) during kidney transplanta- pression increased appetite weight gain, diabetes melli-
tion and treatment of many tus, dyslipidaemia, hypokalaemia, hypocalcae-
kidney diseases mia, osteoporosis, osteonecrosis, hypophos-
phataemia, protein hypercatabolism (PG),
urinary losses of zinc, potassium, calcium, vita-
min C and nitrogen, gastrointestinal ulceration,
impaired wound healing, pancreatitis, impaired
growth in children
Cyclosporine Immuno-suppressant Reduce IL-2 production, spare Hyperkalaemia, hypomagnesaemia, increased
T-suppressor cells, grapefruit uric acid levels, hyperlipidaemia, hyperglycae-
increases CsA blood levels – use mia, oedema and hypertension, anorexia and
with caution, be vigilant of medicine nausea, vomiting, diarrhoea (PG), gingival
interactions hypertrophy, bone resorption, gastro oesopha-
geal reflux disease, dysmorphia, nephrotoxicity
due to increased CsA levels
Muromonab-CD3 Immuno-suppressant Inhibits T-cell effector function Severe fluid retention, hypertension, pulmo-
nary oedema, nausea, vomiting, anorexia,
(Orthoclone OKT3) diarrhoea, abdominal gas/pain (PG)
Mycophenolate Immuno-suppressant Gastrointestinal (GI) bleeding, abdominal
pain, GI symptoms, hypertension, fluid
retention, hyperlipidaemia, hypophosphatemia,
hyperkalaemia (PG)
Sirolimus Immuno-suppressant Inhibits proliferation of immune cells Dyslipidaemia, impaired wound healing,
hypokalaemia
Azathioprine Immuno-suppressant Anti-proliferative Increased risk of infection, pancreatitis
Tacrolimus Immuno-suppressant Inhibits IL-2 synthesis and release Hyperglycaemia, hyperkalaemia, hypomag-
nesaemia, hypertension, gastrointestinal
disturbance
Statins (simvastatin, Dyslipidemia HMG-CoA Reductase inhibitors Diarrhoea, nausea, vomiting, constipation,
atorvastatin) fatigue, muscle pain, rhabdomyolysis, liver
failure
Please refer to patient education general guides (Table 14). The renal diet is complex and it can be challenging to
educate patients, since some renal patients have low literacy levels when it comes to nutrition. Along with the nutrition
guidelines given, the emphasis should be placed on health communication, focusing on providing clear and simple
messages, not using medical jargon, using visual aids while focusing on one dietary aspect at a time and asking patients
to teach back what they were taught59.
The energy intake of the patient must be sufficient to prevent protein from being used as an energy source. These
energy requirements are determined according to the recommended guidelines for acute renal failure (ARF) and CKD
and are usually high. In PD patients, the energy from the dextrose in the dialysate should be considered in calculations;
therefore, the energy supplied by the diet would be less.
18
It is often difficult to achieve high energy requirements due to either low protein intakes or symptoms of uremia. Therefore,
a slow but steady increase in energy requirements may be required. Oral supplementation may be needed, especially
in malnourished patients if oral intake is insufficient.
Guidelines to enhance or maintain energy intake, based on individual requirements, include the following:
• include as many appropriate complex carbohydrates as the meal plan allows. Include simple carbohydrates
within limits in the daily meal plan e.g. sugar, jam, sweets (clear boiled sweets, marshmallows, jelly babies,
peppermints) and cold drinks (carbonated beverages and avoid cola flavoured drinks) to help meet their nutritional
requirements (total energy). Avoid cola flavoured drinks as they are high in phosphate. Sports drinks may be
included to increase energy intake. Mageu can be used as an energy drink in moderation
• the energy density of foods can be increased by adding margarine to porridge and vegetables
• to prevent an increase in blood lipids and lipoproteins, fat in the diet should be derived as much as possible from
mono- and poly-unsaturated food sources. Cholesterol intake should be limited due to enhanced cholesterol
absorption in ESRD60
19
• patients should be educated to choose mostly from the low to moderate K group, however they do not have to
completely exclude the high K group, especially if their K levels are within range and they are on PD, which has
a higher K requirement
• refer to Annexure 3 for the new Renal exchange list of South Africa62
• cooking methods and food preparation, such as leaching, boiling and chopping of vegetables and legumes, can
aid in decreasing the potassium content
• leach potassium out of high-potassium vegetables by soaking vegetables in water before cooking, discarding
the water used for soaking, boiling the vegetables in water and then discarding the water used for boiling as well
• if the potassium level of a patient is high, avoid foods with over 250mg potassium per serving and limit the daily
intake to 1500-2700mg2
• generally, milk is limited to one portion for the day, due to the high potassium and phosphate content, however
more can be allowed on an individual basis
• the focus of lowering dietary potassium intake should be aimed at increasing whole food intake and limiting the
intake of processed food, convenience foods from stores and take-aways63.
• take note that processed foods may contain an increase in potassium salt substitutes in an effort to decrease
sodium content, regulated by legislation
• Phosphate levels are usually high in renal failure patients due to altered bone metabolism.
• Patients should be educated about organic and inorganic phosphates and the bioavailability of phosphates from
these sources.
• Meat and dairy products are the main animal sources of organic phosphate, found in membrane phospholipids
and phosphoproteins, whereas in vegetable sources legumes, whole grains and nuts, it is found as phytate.
• The bioavailability from animal sources are 40 to 80 per cent. This can be higher if Vitamin D is present, vegetables
have an absorption rate of 20 to 40 per cent, because most of the phosphate is found as part of phytate, which
must be hydrolysed by phytase to be absorbed. Phytase is not found in the small intestine, which reduces
absorption further.
• Inorganic phosphate is not found in foods in their natural state, but is usually added. They are mainly additives
used to preserve food to improve palatability and shelf life of foods. The bioavailability is 90 per cent from the
inorganic phosphate, which is the highest absorption rate of the phosphate types. Not all foods are labelled with
phosphate content, which makes it more difficult to identify.63.
• Patients must be educated on limiting high phosphate meats e.g. cheese, eggs, sardines, pilchards or bacon to
one exchange a day. Legumes and wholegrains are allowed (even though high in phosphate, the phosphate in
legumes has reduced bioavailability)64,65. Legumes would include peanut butter, soya beans, baked beans, lentils,
dried beans and peas. Wholegrains would include breads, cereals and other wholegrain starches.
• The most suitable meat exchanges would come from the low phosphate meat groups including beef, lamb,
chicken, fish, lean mince, low fat cottage cheese or tuna.
• Milk and dairy products are limited to one portion per day, due to the high potassium and phosphate content.
• Always check that patients are taking their phosphate binder correctly, i.e. chewing it in the middle of meals (not
before/after eating).
• The focus of lowering dietary phosphate intake should be aimed at increasing whole food intake and limiting the
intake of processed food, convenience foods from stores and take-aways63.
• Emphasis should be placed on reading labels.
5.4.7 Fibre and the gut microbiome
Gut dysbiosis has recently been implicated in affecting the gut micriobiota in CKD patients. This is due to the altered
gut bacteria because of low fibre intake, which favours proteolytic fermentation instead of saccharolytic fermentation.
This increases uremic toxins (p-cresyl sulphate, indoxyl sulphate and trimethylamine oxide (TMNO), which causes the
progression of renal disease or worsens uremia as well as promoting inflammation.66 Saccharolytic fermentation is
achieved by adequate fibre in the diet. Studies have shown a reduction in urea and creatinine in CKD patients with fibre
interventions67.
• It is important to obtain sufficient fibre from a variety of sources, including soluble and insoluble fibres from fruit,
vegetables and especially wholegrains.
• The phosphates in wholegrains have low bio-availability so it may be included within the portion control of the diet.
• Patients can be advised about fruits and vegetables, encouraging low to moderate potassium sources, however
high sources do not have to be completely excluded.
• Although prebiotic supplements, synbiotics and probiotic studies have shown some benefit in the gut microbiome,
it is not recommended at this stage due to insufficient evidence for its adverse effects. Most of these studies have
been small. It is recommended that more research be done to understand the effects of diet, prebiotics, synbitoics
and probiotics on the symbiotic environment and its relation to kidney function. 68.
20
5.5. Transplant patient education
Please refer to the patient education general guidelines (Table 16) for additional information.
The post-transplant nutrition management can be divided into several phases; however, emphasis will be placed on
the immediate post-transplant and intermediate to late post-transplant phase.
In the early post-transplant phase in an uncomplicated surgery, the main emphasis is to manage fluid balance, electrolytes
and acid-base balance. The stress of surgery and the effects of high doses of steroids on nutrient metabolism necessitate
increased energy and protein requirements. The main goals are to promote wound healing, prevent infections and
provide adequate protein and energy to promote visceral protein stores and to correct electrolytes69. Potassium needs
to be monitored very carefully and patients should be advised to avoid high potassium fruits and fruit juices for the first
week post-transplant (depending on patient’s potassium levels). Certain immuno-suppressant medication has the effect
of increasing potassium levels. Other symptoms may include diarrhoea, constipation, nausea and vomiting and needs
to be managed accordingly.
• In the intermediate to late transplant phase, the goals are to prevent the complications of immuno-suppressant
medications, such as obesity, diabetes, hypertension, bone disease, hyperlipidaemia, hyperkalaemia and
malnutrition.57.
• Dietary advice should focus on healthy diet advice and to avoid restrictions from pre-transplant diets.
• Diet, exercise and lifestyle modification has an important role to play in the reduction of insulin resistance, which
can have harmful consequences, and to improve transplant outcomes69.
21
Figure 4: Patient education flow diagram27, 61, 69
22
Table 16: Patient education (CKD) - general guide31
Treatment Conservative Dialysis (HD/PD)
Initial intervention (within Follow-up (3-4 weeks/ Initial intervention (within Follow-up (within 1 month)
Factor first month of referral) as needed) and quarterly first month of referral) and six month intervention
intervention
Self-management Discuss the role and effect Review and reinforce Discuss the role and effect Review and reinforce
skills of diet and medication on self-management skills, of diet and medication on self-management skills,
renal function. including a diet history and renal function and dialysis including a diet history and
relevant feedback thereof. treatment. relevant feedback thereof.
The importance of blood Provide feedback on chang- The importance of blood Provide feedback on changes
pressure control and, if es in weight/nutritional sta- pressure control and, if rele- in weight/nutritional status,
relevant, blood glucose tus, blood pressure control. vant, blood glucose control. blood pressure control.
control and slowing the
progression of renal failure.
Discuss optimal caloric, Recommend changes in Discuss optimal caloric, Recommend changes in nu-
protein and nutrient intake nutrient intake that may protein and nutrient intake trient intake that may improve
e.g. sodium, potassium, improve outcome. e.g. sodium, potassium, outcome.
phosphorous. phosphorous and vitamins
according to type of dialysis
(HD/PD).
Basic dietary guidelines for Provide specific mineral re- Basic dietary guidelines for Provide specific mineral re-
renal failure, and for diabe- striction guidelines according ESKD, and for diabetes, striction guidelines according
tes, include timing of meals to laboratory results. include timing of meals and to laboratory results.
and snacks if indicated. snacks if indicated.
Discuss fluid intake and Review fluid status and Discuss dry weight and fluid Review fluid status and rec-
restrictions, if indicated. recommendations. restrictions, if indicated. ommendations.
Discuss laboratory results Discuss laboratory results Review dialysis adequacy.
and the significance and the significance thereof.
thereof.
Discuss the use and effect Review the appropriate use Discuss the use and effect Review the appropriate use of
of phosphate binders. of phosphate binders. of phosphate binders. phosphate binders.
Discuss medicine-nutrient Review medication pre- Discuss medicine-nutrient Review medication pre-
interactions as indicated. scribed, any changes and interactions as indicated. scribed, any changes and
medicine-nutrient interac- medicine-nutrient interactions.
tions.
Assess comprehension of Assess comprehension of Assess comprehension of Assess comprehension of
education and projected education and projected education and projected education and projected
compliance. compliance. compliance. compliance.
Provide relevant education- Provide and review educa- Provide relevant educational Provide and review educa-
al material, renal exchang- tional material. material, renal exchanges tional material, especially with
es or diabetes exchanges or diabetes exchanges (if changes in dialysis modality.
(if appropriate). appropriate).
Behavioural Encourage exercise as Assess activity and changes Encourage exercise as Assess activity and changes
part of a healthy lifestyle, if in recommendations. part of a healthy lifestyle, if in recommendations.
appropriate. appropriate.
Identify short-term achiev- Reset short-term goals and Identify short-term achiev- Reset short-term goals and
able goals. review long-term goals. able goals. review long-term goals.
Establish follow-up plan. Establish follow-up plan. Establish follow-up plan. Establish follow-up plan.
Initial intervention Follow-up (daily/as Initial intervention (1-2 months post Follow-up (6 months/as
Factor (within 72 hours of needed) transplant) needed)
referral)
Self-management Discuss the role and Review and reinforce Determine previous dietary instruction Review and reinforce
skills effect of diet and medica- self-management skills, and practices. self-management skills,
tion in transplantation. including changes in med- including daily intake
ical status and therapies and output and relevant
e.g. medication, dialysis. feedback thereof.
The importance of blood Provide feedback on Review changes in nutritional status, Provide feedback on
pressure control and, if changes in weight/nutri- blood pressure control and blood changes nutritional status,
relevant, blood glucose tional status, blood pres- glucose control. blood pressure and glu-
control. sure and blood glucose cose control.
control.
23
Discuss optimal caloric, Recommend changes Ensure optimal caloric, protein and Recommend changes
protein and nutrient in nutrient intake that nutrient intake and the use of vitamin/ in nutrient intake that
intake and vitamin/min- may improve outcome, mineral supplementation, depending may improve outcome,
eral supplementation as depending on tolerance of on tolerance of oral intake or changes depending on tolerance
indicated. oral intake or changes in in appetite. of oral intake or changes
appetite. in appetite or chronic
rejection.
Basic dietary guidelines Basic dietary guidelines Specific dietary guidelines as indicat- Provide specific dietary
as indicated and rein- as indicated to improve ed to improve outcome. guidelines according to
force temporary nature of outcome. laboratory results, pres-
recommendations based ence of diabetes, medi-
on medical condition and cine-nutrient interactions,
laboratory results. episodes of rejection and
reinforce temporary na-
ture of recommendations
where applicable.
Discuss fluid intake and Review fluid status and Discuss fluid intake and fluid Review fluid status and
restrictions, if indicated. recommendations. restrictions, if indicated. recommendations.
Discuss laboratory Review laboratory results Discuss laboratory results e.g. sodi-
results e.g. sodium, and relevant changes. um, potassium, phosphate, calcium,
potassium, phosphate, magnesium, lipid profile and the
calcium, magnesium and significance thereof.
the significance thereof.
Discuss medicine-nu- Review medication Discuss medicine-nutrient interactions Review medication,
trient interactions as prescribed, any changes as indicated. especially any changes
indicated, especially and medicine-nutrient in immuno-suppressant
immuno-suppressant interactions. medication prescribed,
medication. and medicine-nutrient
interactions.
Implement nutritional Re-assess nutritional plan Implement nutritional plan as per Re-assess nutritional plan
plan as per individual for adequacy and appro- individual requirements. for adequacy and appro-
requirements. priateness. priateness.
Assess comprehension Assess comprehension of Assess comprehension of education Assess comprehension of
of education and project- education and projected and projected compliance. education and projected
ed compliance. compliance. compliance.
Provide relevant educational material. Provide and review
educational material, es-
pecially if presenting with
chronic rejection.
Behavioural Identify short-term Reset short-term achiev- Identify short-term achievable goals. Reset short-term achiev-
achievable goals. able goals. able goals and review
long-term goals.
Encourage exercise as part of a Assess activity and
healthy lifestyle. changes in recommenda-
tions.
Establish follow-up plan. Establish follow-up plan. Establish follow-up plan. Establish follow-up plan.
24
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55. Ibrahim HN, Nath KA, Hostetter TH. Nutritional requirements of diabetics with nephropathy. In Mitch WE & Klahr
S, editors. Handbook of Nutrition and the Kidney. 3rd ed. USA: Lippincott-Raven Publishers; 1998. P166-200.
56. Heng, A.E. and Cano, N.J.M. (2010). Nutritional problems in adult patients with stage 5 chronic kidney disease
on dialysis
57. Wilkens, K.G. 2012. Medical nutrition therapy for renal disease, In Krause’s Food, Nutrition, & Diet Therapy, 961-
995. 13th ed. Saunders. United states of America
58. Snyman J, editor. MIMS Desk Reference. MDR. 2010; Vol. 45.
59. Dageforde, L.A. and Cavanaugh, K.L. 2013. Health Literacy: Emerging Evidence and Applications in Kidney
Disease Care. Advances in Chronic Kidney Disease. 20. (4).311-319. Doi: 10.1053/j.ackd.2013.04.005
60. Patel, C.2014. The Vegetarian Diet and Chronic Kidney Disease. Available on:http://www.davita.com/education/
article.cfm?educationMainFolder=diet-and-nutrition&category=lifestyle&articleTitle=the-vegetarian-diet-and-
chronic-kidney-disease&articleID=5346
61. Silbernagel, G. et al (2014). Toward Individualized Cholesterol- Lowering Treatment in End-Stage Renal Disease.
Journal of Renal Nutrition. 24:65-71
62. Herselman, M. & Esau, N. 2005. South African renal exchange lists.
63. Biruete A, Jeong JH, Barnes JL, Wilund KR (2017). Modified Nutritional Recommendations to Improve Dietary
Patterns and Outcomes in Hemodialysis Patients. Journal of Renal Nutrition. 27.1:62-70
64. Noori N, et al. (2010). Organic and Inorganic Dietary Phosphorous and its Management in Chronic Kidney
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Disease. Kidney Diseases.4(2), 89-100.
65. Moe, Sm et al. (2011). Vegetarian Compared with Meat Dietary Protein and Phosphorous Homeostasis in Chronic
kidney disease. Clin J Am Soc of Nephrol. 6, 257-264
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A systematic review and meta-analysis of controlled feeding trials. European Journal of Clinical Nutrition.
doi:10.1038/ejcn.2014.237
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a double edged sword. Clinical and Translational Immunology. 5.e86.doi:10.1038/cti.2016.36
69. Chitra, U. and Premalatha, S.K. 2013. Nutritional management of renal transplant patients. Indian Journal of
Transplantation, 7(3), 88–93.
27
7. ANNEXURES
ANNEXURE 1: Enteral product formulation
1) Weight change over past two weeks and last six months
• weight gain, no change, mild weight loss (>0.5kgs but <1kg)
• moderate weight loss (>1 kg but <5%)
• severe weight loss (>5%)
3) Presence of GI symptoms
• few intermittent or no symptoms
• some symptoms for >2 weeks or severe symptoms that is improving
• symptoms daily or frequently >2 weeks
4) Functioning state
• no impairment in strength/stamina or mild to moderate loss and now improving
• mild to moderate loss of strength/stamina in daily activity or severe loss but now improving
• severe loss of strength/stamina or bed ridden
6) Muscle wasting
• little or no loss
• mild-moderate in all areas
• severe loss in some or most areas
7) Oedema
• little or no oedema
• mild-moderate oedema
• severe oedema
Minimum score = 7
Maximum score = 49
1-14 - Well nourished
15-35- Mild to moderate malnourishment
36-49- Severe Malnourishment
Adapted from: Tapiawala, S, Vora, H, Patel, Z, Badve, S, Shah B. 2006. Subjective global assessment of nutritional status of patients with chronic
renal insufficiency and end stage renal disease on dialysis. JAPI.(54):923-926.
28
ANNEXURE 3: South African renal exchange lists (updated 2012)
Meat and Meat Substitute Exchanges – High Phosphate (> 100 mg)
350 kJ, 7 g Prot, 5 g Fat, 0 g CHO, 120 mg PO4, 55 - 430 mg Na, 90 mg K
Canned fish, pilchards in brine 3055 30g 1 heaped DSP 162 6 1.6 0 115 156 126
Canned fish, pilchards in tomato sauce 3102 30g size of small matchbox 159 5.6 1.6 0.2 105 111 126
Canned fish, sardines in oil 3104 30g 1 large / 2 small 253 7.4 3.5 0 147 152 119
Canned fish, sardines in tomato sauce 3087 30g 1 large /2 small 220 4.9 3.6 0.2 110 124 102
Cheese, Cheddar 2722 30g size of small matchbox 494 7.4 9.7 0.5 160 146 25
Cheese, Gouda / Edam / Swiss 2723 30g size of small matchbox 473 7.2 9.5 0.1 170 153 21
Cheese, Mozzarella, grated 2790 30g 2 heaped TBS 350 5.8 6.5 0.7 111 112 20
Egg, boiled or poached 2867 55g 1 extra-large 339 6.9 5.7 0.7 106 69 54
Liver, chicken, simmered 2970 30g 1 liver 190 7.3 1.7 0.3 94 15 42
29
Liver – sheep / lamb, fried 2955 30g size of small matchbox 290 7.7 3.8 1.1 128 37 106
Liver, beef, fried 2920 30g size of small matchbox 265 8 2.4 2.4 138 32 109
Macaroni and cheese, white sauce(WM,HM) 3301 90g 1 heaped LS 642 6 8.4 12.9 112 151 78
Oysters, canned 3068 80g 12 oysters 224 5.7 2 3.1 111 90 183
Bacon, cured, fried / grilled 2906 30g 3 rashers 702 9.2 14.8 0 101 479 146
Cheese, Blaauwkrantz / Roquefort 2726 30g size of small matchbox 460 6.5 9.2 0.6 118 543 27
Cheese, Camembert 2758 30g size of small matchbox 373 5.9 7.3 0.2 104 253 56
Cheese, Parmesan, grated 2762 20g 2 heaped DSP? 376 8.3 6 0.7 161 372 21
Pizza with cheese, tomato & olives, 3353 80g 2 wedges 834 7.2 9.4 19.8 128 456 120
TO BE RESTRICTED
Brains (High phosphate)
Cheese spread/wedges (High phosphate, sodium)
Feta (High phosphate, sodium)
Marmite, Bovril (High phosphate, sodium, potassium)
Nuts, all types (High phosphate, potassium)
Dried fish (Bokkems) (Extremely high in sodium; phosphate not known)
Fish paste (Extremely high in sodium; phosphate not known)
Meat and Meat Substitute Exchanges – Low Phosphate (< 100 mg)
350 kJ, 7 g Prot, 5 g Fat, 0 g CHO, 65 mg PO4, 55 - 430 mg Na, 90 mg K
Food Item Code Portion Energy Protein Fat CHO PO4 Na K
Grams/ml Measure (kJ) (g) (g) (g) (mg) (mg) (mg)
Low in Sodium (55 mg)
Beef stew, with vegetables 3020 60g ~¼ cup 323 6.9 3.7 3.3 53 24 117
Bobotie, regular mince 3023 40g 1 heaped TBS 332 5.8 3.1 6.5 57 161 153
Calamari, fried 3099 30g 8 med rings 214 5.4 2.3 2.3 75 92 84
Canned fish, mackerel, canned 3113 30g size of small matchbox 227 6 3.4 0 81 57 58
Canned fish, tuna in brine, drained 3054 30g 1/4 cup 139 7.7 0.2 0 49 101 71
Canned fish, tuna in oil, drained 3093 30g 1/4 cup 239 8.7 2.5 0 93 106 62
Chicken, cooked without bones 2963 30g 1 small drumstick 200 8.8 1.4 0 59 18 76
Cheese, Brie 4312 30g 416 6.2 8.3 0.1 56 189 46
Chicken, giblets, cooked, simmered 2998 30g size of small matchbox 185 7.8 1.4 0 69 17 47
Chicken stew no skin, with vegetables 4378 60g ~ ¼ cup 266 6.9 2.1 3.3 60 20 114
Cottage cheese, low fat 2729 60g 2 heaped TBS 221 6.3 2.4 1.5 68 97 111
Cottage pie, lean mince, WM, HM 3009 50g 2 heaped DSP 296 7.3 3.1 3 58 26 137
Crab, fresh, cooked 3065 30g 2 TBS 123 6.1 0.5 0 62 84 97
Lobster (crayfish), cooked 3069 30g 172 7.9 0.6 0.9 69 68 94
Duck roasted meat and skin 2995 45g 1 drumstick / 1TBS 618 8.6 12.8 0 70 27 92
Fish, fatty (butterfish, herring), grilled 3082 30g size of small matchbox 246 6.9 3.5 0 91 35 126
Fish, medium fat (snoek), grilled / steamed 3089 30g size of small matchbox 194 8.5 1.4 0 95 32 148
30
Fish, medium fat, battered/crumbed, fried in oil 3084 30g size of small matchbox 285 7.6 4.2 0 85 28 133
Fish, white, battered fried in oil 3094 30g size of small matchbox 302 6.7 4.2 1.8 76 26 115
Fish, low fat, fried in oil 3060 30g size of small matchbox 231 6.3 3.4 0 57 28 92
Goat, roasted 4281 30g size of small matchbox 172 8.1 0.9 0 60 26 122
Kidneys, sheep / lamb, braised 2956 30g 1 kidney 161 7.1 1.1 0 87 45 53
Lasagne, lean mince, cheese source (LFM, HM) 3440 75g 1 heaped LS 505 7.9 4.5 11.6 82.5 67.5 91.5
Meatball, lean mince, without egg 2966 30g 1 small meatball 265 8.3 2.9 0.9 56 29 87
Meat, cooked without bones, beef 4370 30g size of small matchbox 357 8.2 5.9 0 50 28 83
Minced meat, mutton, cooked 3041 30g 3 level DSP 345 7.4 5.9 0 60 24 102
Mopanie worms, canned 4284 60g 257 8.5 2.2 0.4 74 140 139
Mopanie worms, dried 4250 15g 259 8.5 2.2 0.4 75 142 141
Mussels, black / blue, boiled 3085 30g 10 mussels 209 7.1 1.4 2.2 86 111 80
Mutton, leg roasted, meat and fat 2947 30g 1 thin slice 314 7.7 5 0 57 20 94
Mutton, leg and shoulder braised, lean 3036 30g 1 heaped DSP 270 10.1 2.6 0 62 21 78
Food Item Code Portion Energy Protein Fat CHO PO4 Na K
Patty, beef, grilled 2984 40g 1 small 458 9.8 7.9 0 63 31 118
Perlemoen / Abalone, fried 3078 30g 1 slice 232 5.9 2 3.3 NA 177 26
Pork leg, roasted 2958 30g 1 thin slice 332 8 5.3 0 79 18 106
Pork loin, braised 3044 30g size of small matchbox 244 8.9 2.5 0 54 19 110
Shrimps / prawns, cooked 3070 30g 1 heaped TBS 119 6.3 0.3 0 41 67 55
Spaghetti bolognaise, lean mince 3388 75g 1 heaped LS 425 7.7 2.3 11.3 64.5 16.5 120
Spleen, sheep / lamb braised 4340 30g size of small matchbox 188 8.9 1.4 0 72.3 17.4 74.4
Turkey, roasted, meat only 2981 30g size of small matchbox 205 8.8 1.5 0 64 21 89
Veal, chuck, cooked 4331 30g size of small matchbox 247 8.8 2.6 0 66 30 99
Veal, breast, cooked 4356 30g size of small matchbox 290 7 4.6 0 58 35 91
Venison, roasted, fine 2913 30g 1 heaped DSP 190 9.1 1 0 68 16 101
31
Ants, flying dried 4333 15g 373 5.7 7 0.9 91 295 71
Biltong / dried sausage, beef 3021 20g 6 slices 340 6.6 5.1 1.8 81 443 119
Chicken pie 2954 70g 1 small square 1119 4.8 17.4 22.5 50 270 71.4
Chicken liver pate 2922 50g 413 6.8 6.6 3.3 87.5 193 47.5
Corned meat, beef, canned 2940 30g 2 thin slices 290 5.9 4.5 1.5 33 302 41
Frankfurters 2937 60g 1 Frankfurter 790 6.8 17.5 1.6 52 672 100
Ham, cooked, 15cm X 9cm 2967 30g 1 thin slice 223 5.2 3.2 0.9 74 395 99.6
Meat pie, steak ‘n kidney 2957 90g 1 wedge 1350 8.3 20.6 25.7 76.5 356 88
Pastrami, turkey 4343 40g 4 thin slices 228 7.4 2.5 0.7 80 418 104
Polony/cold meat, beef and pork, 10 cm diam 2919 60g 4 thin slices 776 7 17 1.7 55 611 108
Pork sausages, thin, grilled 2932 30g 10 cm piece 452 5.9 9.4 0.3 55 388 108
Salami / Russians, 5cm diam 2948 30g 5 thin slices 512 6.9 10.3 0.8 43 558 113
Sausage, beef and pork / Boerewors, thick, grilled 2931 60g 10 cm piece 974 8.3 21.8 1.6 64 483 113
Smoked fish – Haddock 3061 30g size of small matchbox 140 7.6 0.3 0 75 229 125
Vienna sausage, beef and pork, canned 2936 70g 2 large 799 7.2 17.6 1.4 34 667 71
Meat and Meat Substitute Exchanges – Legumes
350 kJ, 7 g Prot, 5 g Fat, 15 g CHO, 120 mg PO4, 55 - 430 mg Na, 245 mg K
Food Item Code Portion Energy Protein Fat CHO PO4 Na K
Grams/ml Measure (kJ) (g) (g) (g) (mg) (mg) (mg)
Low in Sodium (55 mg)
Biryani, with lentils, ghee, no meat/ potato 3194 150g 2 heaped LS 980 6.6 6.9 33 125 5 224
Biryani, with lentils, oil, no meat/potato 3193 150g 2 heaped LS 980 6.6 6.9 33 125 3 224
Dried beans, cooked, kidney / white 3183 90g 3/4 cup 453 7 0.4 12.3 100 2 457
Dried beans, cooked, sugar 3205 90g 3/4 cup 553 6.4 0.5 17.6 110 12.6 331
Dried peas, cooked 3177 90g 3/4 cup 464 7.5 0.4 13.7 89 2 326
Lentils, cooked 3203 90g 2/3 cup 455 7.7 0.2 12.3 116 5 243
Lentils split, cooked 3179 90g 2/3 cup 459 8.1 0.4 13.1 162 2 332
Peanut butter, smooth style 3485 30g 2 level DSP 786 7.4 15 4.4 97 143 216
Peanuts, roasted, unsalted 3452 30g 1 med handful 778 7.9 14.8 3 155 2 205
Soup mix, dried, 4-in-1, raw 3175 50g 766 7.5 1.1 29.3 128 12 NA
Soya beans, cooked 3188 50g 4 level TBS 392 8.3 4.5 2.4 123 1 258
Tofu, raw, (soybean curd) 3202 100g 348 8.1 4.8 0.7 97 7 121
32
High in Sodium (430 mg)
Baked beans, canned in tomato sauce 3176 90g 2 heaped TBS 482 4.3 0.5 16.1 94 357 266
Toppers, cooked 3196 140g 3/4 cup 584 8.1 2.4 17.9 141 552 346
TO BE RESTRICTED
Milk, low fat / 2% fat, fresh 2772 125g/125ml 1/2 cup 266 4.1 2.5 6.1 111 58 190
Milk, low fat powder (vit A, B, D, E, folate
2825 10g 1 heaped DSP 163 3.4 0.6 5 97 54 179
added)
Milk powder, blend, medium fat, (Numel) 2794 15g 1 heaped TBS 254 4.2 1.7 7 126 76 234
Milk, skim, fresh 2775 125g/125ml 1/2 cup 186 4.3 0.3 6.1 126 65 208
Milk, full fat / whole, fresh 2718 125g/125ml 1/2 cup 328 4.0 4.3 6 113 60 196
Nesquik, powder (+ 100ml wm) 2830 10g powder 1 heaped DSP 437 3.3 3.6 14.6 96 49 172
Ovaltine powder, no sugar (+ 100ml wm) 2754 10g powder 1 heaped DSP 299 3.6 3.7 6.0 102 54 177
33
Soya milk, plain 2737 125g/125ml 1/2 cup 186 3.5 2.4 0.6 61 15 176
Soya milk, fortified 4351 125g/125ml 1/2 cup 260 3.3 3.3 5 44 49 113
Baked custard, low fat(egg), plain 2785 125g/125ml 1/2 cup 563 5.8 4.1 18.4 123 69 158
Baked custard, skim (egg), plain 2745 125g/125ml 1/2 cup 505 5.9 2.5 18.4 133 75 170
Ice cream, kulfi 4323 100g 1764 5.4 39.9 11.5 150 76 240
Ice cream sorbet (8% fat) 3491 80g/125ml 2 scoops 598 2.6 7 17.4 80 61 136
Ice cream (regular 10 % fat) 3483 80g/125ml 2 scoops 694 2.8 8.8 18.9 84 64 159
Ice cream (rich 16 % fat) 3519 80g/125ml 2 scoops 832 2.8 13 17.9 76 45 127
Ice cream, soft serve (13 % fat) 3518 135g 1 med cone 1253 5.5 17.6 30 157 82 239
Milk, condensed, full fat, sweetened 2714 50g 2 level TBS 691 4.0 4.4 27.2 127 64 186
Milk ice (frozen on stick) 3530 100g 601 3.9 4.3 22.1 99 80 202
Milk shake, vanilla, purchased 2788 125g/125ml 1/2 cup 600 4.9 3.8 22.1 144 119 229
Pancake / Crumpet, plain, wm, sun oil 3238 70g 1 pancake 808 4.4 11 19 78 34 102
Food Item Code Portion Energy Protein Fat CHO PO4 Na K
Sweets, chocolate coated bar 3997 55g 1 lunch bar 1089 2.8 12.4 34.3 80 91 157
Sweets, chocolate, Kit kat 4024 50g 1 medium 1076 4.0 13.3 30.3 95 54 165
Sweets, chocolate, milk 3987 50g 1/2 X 100g slab 1151 4.3 15.3 30.1 120 60 210
Sweets, chocolate, white 4023 50g 1/2 X 100g slab 1160 4.7 16.1 28.7 115 55 175
Yoghurt, frozen 4324 75g 1/2 cup 515 3.0 4.2 18.2 97 65 158
Yoghurt, wm, curry spice (khuri) 2786 125g/125ml 1/2 cup 520 5.3 7.3 8.8 131 73 265
TO BE RESTRICTED
Chocolates with coated nuts, raisins (high in potassium, sodium and phosphate)
High protein milk drinks e.g. drinking chocolate powder (high in phosphate)
Puddings, instant (very high in phosphate)
*Creamer, non-dairy powder (cremora, coffee-mate) - only 10 g/d (kJ, Prot, 4 G Fat, 6 g CHO, 42 mg PO4, 18 mg Na, 81 mg K)
34
Starch Exchanges – Low Potassium (< 100 mg)
350 - 835 kJ, 2 g Protein, 0 - 10 g Fat, 20 g CHO, 40 mg PO4, 70 mg Na, 50 mg K
Barley, pearl cooked 3368 75g 3 heaped TBS 397 2 0.4 17.9 41 7 70
Brown bread / rolls (fortified) 3211 30g 1 slice / 1 roll 309 2.7 0.4 13 28 194 68
Crumpets (wm, sunflower oil) 3238 25g 1 crumpet 289 1.6 3.9 6.7 28 12 37
Jelly 3983 120g ~ 1/2 cup 320 1.4 0 17.4 1 6 6
Maize meal cooked, crumbly porridge 3401 50g 1 heaped TBS 410 2.4 1.0 21 50 3.5 64
Maize meal cooked, soft porridge 3399 200g 2 heaped LS 400 2.4 1 21 80 8 44
Maize meal cooked, stiff porridge 3400 100g 1 heaped LS 520 2.8 1.1 27 80 7 71
Maize, rice cooked (white) 3250 100g 2 heaped LS 424 2.2 0.2 21.5 15 1 28
Maize, samp cooked (white) 3280 100g 1 heaped LS 424 2.2 0.2 21.5 15 1 28
Maltabella, cooked 3241 200g 5 heaped TBS 356 2.2 0.6 17 52 NA 86
Oats, cooked 3239 110g 1 heaped LS 307 1.9 1.8 10.6 85 2 63
Pasta, cooked 3262 40g 1 heaped TBS 236 1.9 0.3 10.7 22 0.4 12
Pearl wheat, cooked 3249 60g 2 heaped TBS 229 1.9 0.3 9.4 24 2 41
Provita biscuits 3235 20g 3 biscuits 354 2.3 1.7 14.4 35 142 41
35
Puffed rice - sweetened (cocopops) 3372 30g 1 cup 486 1.6 0.1 26.5 42 227 26
Puffed wheat, plain 3325 15g 1 cup 247 2.2 0.2 11.4 53 1 52
Pumpernickel bread 3283 25g 1 slice 282 2.1 0.4 11.5 40 145 48
Rice, brown, cooked 3315 90g 3 heaped TBS 422 2.3 0.8 19.2 75 5 39
Rice, white, cooked 3247 75g 3 heaped TBS 398 2 0.2 20.6 35 2 29
Scone, plain 3237 25g 1 small scone 401 2 4 12.5 27 77 32
Scone, whole-wheat (hm / wm) 3320 25g small 383 2.7 3.9 9.4 64 73 75
Tasty wheat, cooked 3240 100g 1 heaped LS 220 1.5 0.2 11 17 1 17
White bread / rolls* (fortified) 3210 30g 1 slice / 1 med roll 311 2.6 0.4 13.8 29 196 64
Whole-wheat bread / rolls 3212 30g 1 slice / 1/2 roll 325 2.5 0.6 13.3 53 114 64
High in Energy (835 kJ) and / or Fat (10 g)
Apple tart, short crust 3224 75g 1 large wedge 700 2 5.9 25.4 23 115 84
Baked cheese cake, egg and cream 3293 50g 1 small wedge 867 2.7 16.2 12.7 48 155 55
Banana loaf (wm, hm) 3333 40g 1 cm slice 562 1.9 4.4 21 26 84 84
Beskuit, whole-wheat, buttermilk (hm) 3255 30g 1 rusk 597 2.7 6.2 16.8 65 130 77
Butter cake, plain (wm, hm) 3288 50g 1 small piece 754 2.6 6.2 27.9 37 119 41
Buttermilk rusk, white, commercial 3329 30g 1 rusk 569 2.4 4.5 20.6 50 164 61
Food Item Code Portion Energy Protein Fat CHO PO4 Na K
Carrot cake, plain (egg, sun oil) 3392 50g 1 med wedge 791 2.1 9.9 22.3 82 157 48
Chocolate éclair with cream filling 3268 50g 1 med 802 2.1 11.9 19 37 75 44
Commercial cookies with filling 3217 30g 2 cookies 611 1.5 5.6 21.9 25 67 36
Commercial cookies, plain 3216 30g 3 biscuits 579 2.2 4 22.7 25 123 42
Corn flakes, plain 3243 40g 1 cup 642 3.10 0.1 33.2 20 484 42
Cream crackers 3230 25g 3 crackers 507 2.4 4.1 17.1 28 152 30
Doughnut, plain 3232 45g 1 small 793 2.7 9.8 21.2 36 104 39
Ginger bread (hm) 3253 40g 1 cm slice 662 2.1 5 25.4 29 127 54
Madeira cake, commercial 3291 50g 2 thin slices 866 2.7 8.5 29.2 60 190 60
Noodle salad 3336 95g 1/2 cup 817 3.1 12.3 17.6 39 79 56
Popcorn, sugar coated / candied 3359 100g 2 cups 2165 2.1 20 77.6 58 56 75
36
Rice crispies 3252 40g 1 cup 642 2.6 0.1 34.7 56 529 40
Roti with butter 3356 50g 15 cm diam small 1096 2.4 18.7 20.8 29 186 35
Roti with oil 3358 50g 15 cm diam small 1245 2.3 22.8 20.7 23 1 29
Samoosa, mutton filling 3355 40g 1 small 1000 2.0 22.4 7.2 25 13.2 48
Sweetcorn fritter 3254 50g 2 small 876 2.8 15 15.4 58 124 100
Tipsy tart 3323 60g 1 med wedge 729 1.8 2.6 34.3 25 25 83
Chicory (witloof), raw 3947 50g 2 heaped TBS 44 0.5 0.1 0.5 13 1 106
Coleslaw, commercial 3707 50g 1/2 cup 328 0.8 5.6 3.9 18 135 90
Coleslaw, mayonnaise, raisins 3705 50g 1/2 cup 302 0.8 5.5 4.3 17 87 86
Cucumber, raw, English 4119 50 g 5 med slices 31 0.4 0.1 1 14 6 84
Leek, cooked 3833 100 g 1/2 cup 150 0.8 0.2 6.6 17 10 87
37
Mixed vegetables (carrot, corn, peas, beans) 3727 75 g 1/2 cup 201 1.7 0.4 6.2 38 26 109
Mixed vegetables(carrot, cauliflower, beans) 4265 75 g 1/2 cup 98 1.1 0.2 2.2 29 25 101
Onion, cooked, whole 3773 50 g 2 small or 1 med 96 0.5 0.1 4.4 15 7 81
Onion, raw 3755 30g 2 slices 58 0.3 0 2.6 10 5 54
Peas, fresh, cooked 3719 50g 2 heaped TBS 182 2.7 0.4 4 31 7 104
Peas, frozen, cooked 4146 50g 2 heaped TBS 176 2.6 0.4 2.7 46 4 54
Pepper, sweet, yellow, raw 4153 25g 4 med slices 33 0.3 0.1 1.4 6 1 53
Sweetcorn, cream style, canned 3726 65 g 1/4 cup 212 1 0.2 10.1 31 172 81
Sweetcorn, whole kernel, canned 3942 50 g ~1/4 cup 156 1 0.2 7.3 26 107 82
Tomato ketchup / sauce 3139 25g 1 level TBS 120 0.3 0.1 6.2 10 146 116
Vegetable Exchanges – Moderate Potassium (120 – 200 mg)
Asparagus, cooked (green) 3695 90g 1/2 cup 100 2.1 0.3 1 49 0 191
Beetroot, cooked with skin (flesh only) 3698 50 g 1/2 med 108 1 0 4 18 30 145
Beetroot leaves, cooked 3914 20g 1 large DSP 30 0.5 0 0.5 8 48 182
Brinjal, cooked (including skin) 3700 90 g 1/2 cup 94 0.6 0 2.9 21 4 160
Brussels sprouts, cooked 3703 80 g 1/2 cup 120 2.2 0.1 1.8 46 7 187
Calabash / Gourd (white), boiled 4212 100g 120 0.6 0 3.7 13 2 170
Carrot salad, pineapple, orange juice 3710 65g 1/2 cup 124 0.5 0 5.1 12 11 142
Carrots, cooked, rings 3757 80 g 1/2 cup 130 0.7 0.1 4.2 23 23 125
Carrots, raw, grated 3709 50g 1/2 cup 85 0.5 0 3.2 12 12 121
38
French salad (lett, tom, cuc), no dressing 3921 70g 1/2 cup 55 0.6 0.1 1.7 19 5 130
Green beans, cooked, long pieces 3696 65 g 1/2 cup 89 1.2 0.1 1.7 24 3 168
Kalahari truffle, raw 4195 50g 191 2.1 1.8 0.4 71 2 145
Mushroom, raw, sliced 3842 45g 1/2 cup 60 1 0.1 1.2 36 5 132
Pumpkin, summer, patty pan, sliced 4181 100g 3 heaped TBS 81 1 0.2 1.4 28 1 140
Pumpkin, winter, white, cooked 4164 105g 1/2 cup 97 0.7 0.1 3 18 2 165
Pumpkin, winter, hubbard, cooked 4177 105g 1/2 cup 142 0.7 0.1 5.9 20 2 165
Spinach, cooked (Swiss chard) 3913 90 g 1/2 cup 121 2.4 0.3 1.8 32 129 159
Sweetcorn, cooked 3725 65 g 1/4 cup 345 2.1 0.8 14.5 67 11 162
Mixed vegetables, canned 4264 140g 1/2 cup 277 2.9 0.1 9.7 46 532 294
Mushroom, cooked, whole 3729 90 g 1/2 cup 120 2.1 0.2 2.4 66 9 239
Okra, boiled 3939 100g 1/2 cup 162 1.9 0.2 4.7 56 5 322
Pumpkin, summer, gem, cooked 3760 90g 1/2 large 87 0.5 0.1 3.2 19 1 232
Pumpkin, winter, butternut, cooked 3759 105g 1/2 cup 247 1.6 0.1 11 45 2 288
Spinach, small leaf, boiled 3761 90g 1/2 cup 114 2.7 0.3 1.3 50 63 419
Spinach, small leaf, raw 4167 50g 62 1.5 0.2 0.4 25 40 279
39
Tomato and onion stew, with sugar 3910 75g 1 heaped LS 129 0.8 0.2 5.3 24 7 203
TO BE RESTRICTED
40
Pear, dried, raw 3585 12g 1 half 148.5 0.3 0.1 7.5 7 0.5 64
Fruit Juice
Apple juice, Ceres / Liquifruit 3606 125 ml 1/2 cup 288 0.1 0 16.6 9 3 113
Apricot juice, Liquifruit 3610 125 ml 1/2 cup 279 0.4 0 15.3 14 3 85
Grape juice, Ceres / Liquifruit 3690 125ml 1/2 cup 304 0.1 0.1 17.4 14 5 53
Guava juice, Ceres / Liquifruit 3629 125 ml 1/2 cup 260 0.3 0.1 14.4 11 8 81
Litchi juice, Ceres 3684 125 ml 1/2 cup 274 0.1 0 15.9 14 5 59
Mango juice, Ceres 3683 125 ml 1/2 cup 268 0.1 0 15.5 11 3 39
Mango and orange juice, Liquifruit 3681 125 ml 1/2 cup 291 0.4 0.1 16.4 15 3 94
Orange juice, Ceres, Liquifruit 3638 125ml 1/2 cup 273 0.4 0.1 15.1 16 5 119
Peach juice, Ceres 3687 125 ml 1/2 cup 273 0.5 0.1 15.1 11 4 110
Strawberry juice, Liquifruit 3654 125 ml 1/2 cup 261 0.4 0.1 14.6 15 4 66
Canned or Cooked Fruit
Apple, fresh, stewed with sugar 3603 120g 1/2 cup 509 0.4 0.5 25.7 10 1 106
Fruit salad, canned in syrup 3580 140g 1/2 cup 491 0.4 0.1 26.2 13 8 112
Food Item Code Portion Energy Protein Fat CHO PO4 Na K
Grams/ml Measure (kJ) (g) (g) (g) (mg) (mg) (mg)
Litchi, canned in syrup 3631 125g 1/2 cup 395 0.5 0 22.1 15 3 94
Peach salad, curried/atchar/pickles 3693 45g 1 heaped TBS 153 0.3 0 8 9 2 61
Peach, canned in syrup 3567 125g 1/2 cup 394 0.6 0.1 21 13 6 104
Pear, canned in syrup 3583 130g 1/2 cup 410 0.3 0.1 21.8 13 7 107
Pineapple, canned in fruit juice 3647 90g 1/2 cup 249 0.4 0.1 13.4 5 1 110
Pineapple, canned in syrup, pieces 3648 90g 1/2 cup 332 0.2 0.1 19 6 1 94
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Gooseberry 3622 50g 10 berries 125 1 0.4 3 20 0.5 137
Grapefruit 3546 100g half 165 0.7 0.1 6.9 16 3 134
Guava 3551 50g 1 small 145 0.4 0.2 3.9 12 0.5 132
Mango 3556 100g quarter 303 0.6 0.2 15.3 11 1 164
Melon, green 3575 60g 3 cm wedge 115 0.4 0.1 5.4 13 7 162
Minneola, peeled 4227 100g 201 0.7 0.2 9.3 19 2 177
Naartjie / Tangerine 3558 100g 1 med to large 230 0.9 0.2 10 15 5 139
Pawpaw, cubes 3563 100g 4 heaped TBS 186 0.4 0.1 8.6 7 7 192
Canned or Cooked Fruit
Fruit cocktail, canned in fruit juice 3664 140g 1/2 cup 337 0.6 0 17.1 25 7 168
Fruit cocktail, canned in syrup 3665 140g 1/2 cup 451 0.6 0.1 24.1 15 8 123
Gooseberry, canned in syrup 3621 130g 1/2 cup 686 0.7 0.3 36 30 4 157
Grapefruit, canned in fruit juice 4215 125g 1/2 cup 109 0.5 0.1 4.8 10 6 121
Grapefruit, canned in syrup 3547 125g 1/2 cup 345 0.8 0.1 18.8 13 3 161
Guava, canned in syrup 3553 105g 1/2 cup 385 0.4 0 17.1 12 7 126
Mango, canned in syrup 3633 125g 1/2 cup 449 0.4 0 25.1 13 4 125
Peach, canned in fruit juice 3640 125g 1/2 cup 288 0.5 0 14.9 26 6 194
Pear, canned in fruit juice 3643 130g 1/2 cup 256 0.4 0 12.4 16 5 125
Fruit Exchanges – High Potassium (> 200 mg)
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Dried Fruit
Currants, dried 3662 30g 3 heaped DSP 388 0.9 0.2 20 30 5 270
Dried fruit sweets 3995 40g 3 large sweets 553 0.6 0.1 29.6 21 5 214
Fig, dried, raw 3557 40g 2 figs 484 1.2 0.5 22 27 4 285
Peach, dried, raw 3568 25g 2 halves 283 0.9 0.2 13.1 30 2 249
Prune, dried, raw 3596 30g 3 prunes 339 0.8 0.2 17 24 1 224
Tomato juice, Ceres 3976 125ml 1/2 cup 166 1.0 0.1 7.1 1.3 32.5 294
Canned or Cooked Fruit
Apricot, canned in syrup 3535 135g 1/2 cup 402 0.5 0.3 21.5 15 12 201
Apricot, canned in fruit juice 3607 135g 1/2 cup 273 0.8 0 13.6 30 5 243
TO BE RESTRICTED
Guava roll, dried (high potassium)
Sugar Exchanges
Coconut ice 4011 20g 1 med piece 381 0.3 2.6 15.9 8 5 22
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Super C sweets (129 mg vit C / 10g) 4022 10g 2 sweets 177 0.1 0.1 10.2 0 1 0
Sweets, hard boiled or soft jelly type 3986 10g 2 small sweets 160 0 0.1 9.3 1 2 0
TO BE RESTRICTED
Assorted chocolates (high in protein, potassium, sodium and phosphate)
Chocolate coated bars/nuts/raisins (high in protein, potassium, phosphate and sodium)
Dark/bittersweet chocolate (high in protein, potassium and phosphate)
Fudge/toffee (high in protein, potassium, sodium and phosphate)
Fat Exchanges
Cream, fresh, 20% fat 3481 15g 1 level TBS 154 0.4 3.8 0.5 11 6 17
Margarine, light (soft) 3521 10g 2 level TSP 302 0 8 0.1 0 153 1
Margarine, med fat (PUFA) 3496 10g 2 level TSP 306 0 8.3 0 0 40 1.0
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Mutton tallow 3497 5g 1 level TSP 185 0 5 0 NA NA NA
Olives, ripe / canned / pitted 3658 25g 5 Olives 130 0.2 2.7 0.8 1 218 2
Salad cream 3489 10g 1 heaped TSP 148 0.1 3.3 1.5 4 96 4
Salad dressing, low fat 3505 30g 2 DSP 175 0.3 3.9 1.6 0 142 1
Sandwich spread 3552 10g 2 level TSP 165 0.1 3.4 2.2 NA NA NA
TO BE RESTRICTED
Nuts, salted (High in phoshate, sodium and potassium)
Nuts, unsalted (High in phosphate and potassium)
Drink Exchanges
Cold drink, carbonated 3981 250ml 1 med glass 438 0 0 25.8 8 17.5 2.5
Cold drink, squash, diluted 3982 250ml 1 med glass 298 0 0 17.5 2.5 12.5 10
Liqueur 4040 25ml 1 liqueur glass 360 0 0.1 11.6 1.5 2 7.5
Liqueur, with cream 4055 25ml 1 liqueur glass 346 0,7 3.9 5.2 13 23 8
Mahewa / Magou 4056 125ml 1/2 cup 199 1.0 0.4 9.8 48 0 23
Sherry, dry / med, Vermouth 4043 50ml 1 sherry glass 225 0,1 0 2.1 4.5 4.5 46
Sherry, sweet / port, Muscadel 4032 50ml 1 glass 291 0,1 0 5.9 4.5 4.5 46
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Powerade NA 125ml 1/2 cup 156 0 0 9.4 0 28 21
Coffee, brewed, instant 4037 180 ml 1 tea cup 16 0.2 0 0.7 2 3.6 97
Cold drink, artificially sweetened / diet squash 3999 250ml 1 med glass 7.5 0.3 0.0 0.3 25 27.5 2.5
Tea, Ceylon, brewed 4038 180ml 1 tea cup 9 0 0 0.5 1.8 5.4 67
TO BE RESTRICTED
All types of beer (high in phosphate, potassium)
Ciders, sweet (high in potassium)
Cola drinks e.g. Coke, Pepsi (high in phosphate)
Wine (high in potassium)
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National Department of Health
Civitas Building
Cnr Thabo Sehume and Struben Streets
Pretoria
0001