Guidelines of Application of Master’s Programs

Master’s Program in Medical Sciences

Master’s Program in Public Health
Graduate School of Comprehensive Human Sciences,
University of Tsukuba

NUMBER OF STUDENTS TO BE ADMITTED

Limited

QUALIFICATION OF APPLICANTS

The qualification for the admission includes at least one of the followings:
(1) 4-year College Degree Holder.
(2) Persons who have completed 16 years of school education outside Japan.
(3) Persons who have been qualified through our admission screening and was judged to have
accomplished equivalent to 4-year College degree. The applicant must be 22 years or older before
enrollment to the program.*
* The degree qualification will be examined individually.

To apply for Dual Master’s Degree Program, the applicant must be enrolled in: The University of Medicine and Pharmacy
at Ho Chi Minh City (Vietnam), University of Science at Ho Chi Minh City (Vietnam) or National Taiwan University.

PROFICIENCY IN ENGLISH

It is necessary for applicant to demonstrate an adequate command of the English language to benefit from
studies at this University. All applicants, if their first language is not English or if their studies at university have
not been conducted solely in English, must demonstrate English language proficiency by taking the Test of
English as a Foreign Language (TOEFL) or the International English Language Testing System (IELTS) and
having their score reported directly to University of Tsukuba, Graduate School of Medical Sciences (TOFEL
center code: 7902). TOEFL and IELTS score reports must be dated within two years of enrollment in this
University. Photocopies are accepted.

REQUIRED DOCUMENTS

1 Application Form Fill out the attached application form designated by University of Tsukuba.
Please select which program and term you wish to apply.
2 Reference Form Applications will be considered with academic references. Reference form
should be accompanied with at least one letter of recommendation.

3 Picture Attach a picture of yourself taken within three months, facing forward without
hat on the Application Form Size: 4 cm x 3cm (h x w).

4 Application Fee 30,000 yen (will not be charged to the applicants with Japanese Government
Monbukagakusho Scholarship or if applied for Dual Master’s Degree
Program). Payment by credit card is available at:
https://e-shiharai.net/english/?schoolcode=OPU5100850000000
Due by application deadline. Payment in Japan is available through post
office, banks, convenience stores and various banking institutions.
Please contact for the instruction by e-mail: [email protected].

5 Certificate of Graduation Submit a certificate which fulfills our qualification requirements,

Normally from the University/College (or the department) where degree
was awarded.
6 Transcript All applicants are required to provide evidence of their academic
qualifications for the application. Submit a transcript of the school, which
fulfills our qualification requirements, normally from the university (or the
department) where a degree was awarded. If you are a transfer student,
submit transcripts from both schools, before and after the transfer from your
current University.

7 English Language If English is not your first language, request your TOEFL or IELTS score
Proficiency sent directly to this University (TOFEL code: 7902).
Photocopies are accepted.
8 Photocopy of ※ If you do not have a passport yet, you are required to submit Family Register
your passport or Certificate of Citizenship issued by your home country.

APPLICATION PROCEDURE
Please verify all the documents carefully and submit the documents to:
Academic Service Office for the Medical Sciences Area
University of Tsukuba
1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan
Please use the attached recommendation letter form. The letter may be sent from the referee as an e-mail
attachment or with the application forms in a sealed envelope.
Information about Exam will be issued by e-mail when the application documents are accepted.

Applicants must contact their prospective supervisor about the specialized research field in advance.
<Click here for the contact information (of the program) about the research fields.>
Application Period: Please refer to our web page for the application deadline.

SELECTION METHOD

Selection will be based on (a) Academic records (b) Oral examination (c) English proficiency during the
interview. Prospective applicant will be contacted by e-mail after the preliminary screening based on the
submitted documents. Date and location of an interview will be arranged. The applicant will be able to select
the venue where the oral examination will be offered.

ADMISSION PROCEDURE

Succeed applicants will receive an instruction on the admission procedure by e-mail. An official letter from
the University of Tsukuba will be sent by mail.

TUITION AND FEES

Admission Fee: 282,000 yen (will not be reimbursed once received).

Tuition Fee: First Half of Academic Year (April - September): 267,900 yen
Second Half of Academic Year (October - March): 267,900 yen
*Tuition Fees Amount: 535,800 yen annually

*Applicants are advised to make a sufficient financial plan for their tuition fee and living expenses in Japan.

Both tuition and fee are waived for (a) Dual Master’s Degree candidate (b) applicants with
Japanese Government (Monbukagakusho) Scholarship.

NOTES

1) Application that is incomplete will not be processed.

Validation seals of the institution are required on the copies of Certificate of Graduation and Academic
Transcript.
2) Application documents will not be returned to the applicants.
3) The inquiries about the result of Achievement Test are not accepted.
4) Please contact the International Office of further questions on admission or application procedure.
E-mail: [email protected].
 Application Form for Master’s Programs
Master’s Program in Medical Sciences
Master’s Program in Public Health
Graduate School of Comprehensive Human Sciences, University of Tsukuba

PLEASE PRINT OR TYPE ALL SECTIONS

1. APPLICATION FOR: □ F all (October), 2020 □ Spring (April), 2021

□ Master of Public Health Program (Two-years)
□ Master’s Program in Medical Sciences (Two-years; including Japanese applicant living abroad)
□ Dual Master’s Degree Program
2. PERSONAL DATA

Family Name Middle Name

First Name Title (Mr./Ms./Dr., etc.)
Nationality Date of Birth (d/m/y)
Address
Postal code
Telephone Mobile
E-mail Skype ID

3. PROPOSED STUDIES

List the 2nd and 3rd choices in case the 1st choice is not selected.

Research Field Supervisor

1st choice :
2nd choice :
3rd choice :

4. DEGREE OR DIPLOMAS AWARDED OR TO BE AWARDED

Degree Conferred or
Course Dates
University / College (AA, BA, Major expected date
MSc, etc.) (month/year) (month/year)

to
to
to
to

5. EMPLOYMENT HISTORY

Type of Contract Dates

Name and Address of employer
(fixed, temporary or Position (month/year)
(including country)
permanent)

to
to
to
to
 6. LANGUAGE

First Language Other Language

English Language Test Taken Date of Test Overall Written

(e.g. TOEFL, IBT) (month/year) Score Score

Official copy of English language proficiency test must be sent to the Registrar office when the results are available.

7. LETTER OF RECOMMENDATION

If you have research experience in academic institutions during the past 5 years, you are required to obtain letters of
recommendation from faculty who is familiar with your study. If you have any work experience, the second recommender should
be from your employer. If you have no record of employment, the second recommender should be from another academic.

FIRST RECOMMENDER SECOND RECOMMENDER

Name Position Name Position
Address Address
Tel Fax Tel Fax
E-mail E-mail

YOU SHOULD SEND YOUR REFERENCES IN A SEALED ENVELOPE WITH YOUR APPLICATION FORM
You should send your reference letter in a sealed envelope with your application forms or ask the recommender to send it
directly to the International Office at the University of Tsukuba, Medical Branch.

8. FINANCIAL PLAN (Applicant for Dual Master’s Program do not need to complete this section)

Who is paying your tuition?

□ I will pay my own fees.

□ I have been awarded for sponsorship. I will send an original document to Registrar and complete the details below.
□ I have applied for sponsorship. Decision expected (month/year)

NAME & ADDRESS OF SPONSOR AMOUNT OF AWARD

Who is paying your living costs?

□ I will pay my own fees.
□ I have been awarded sponsorship. I will send an original document to Registrar and complete the details below.
□ I have applied for sponsorship. Decision expected (month/year)

NAME & ADDRESS OF SPONSOR AMOUNT OF AWARD

I certify that the statements made by me on this form are correct and complete. I certify that I will not be concurrently
registered for another Degree of the University of Tsukuba. I understand that, if admitted to the University, the University
will not be able to provide any financial assistance. To be signed and date by applicant.

Signature Date:
Field of Study & Study Program

(1) Describe your current field of study:

(2) Describe your study and research you plan to pursue (use additional pages if necessary) :
Reference Form for Graduate Program in Medical Sciences
Graduate School of Comprehensive Human Sciences, University of Tsukuba

PLEASE TYPE OR PRINT AND COMPLETE ALL SECTIONS

TO THE APPLICANT: APPLICANT DETAILS

(Applicant should complete this part and submit this form to the recommender)
Family Name Middle Name
First (Given) Name Title (Mr./Ms./Dr., etc.)
Date of Birth (day/month/year)
Program applied for:

TO THE RECOMMENDER: PLEASE COMPLETE BOTH PAGES

The above student is applying to the Graduate Program in Medical Sciences at the University of
Tsukuba. To help us in the selection process, please fill out the required information.

APPLICANT’S INFORMATION
How long have you known the applicant?
What is your relationship with the applicant? (e.g. student/employee)

RECOMMENDER’S INFORMATION
Name
Position/Title
Organization
E-mail Telephone

ASSESSMENT

Please assess the applicant on a scale of Excellent (highest) to Poor (lowest) in relation to the
following criteria. Please check the appropriate criteria.

Very Unable to
Excellent Good Good Fair Poor comment
Intellectual ability □ □ □ □ □ □
Written communication skills □ □ □ □ □ □
Oral communication skills □ □ □ □ □ □
Ability to meet deadlines □ □ □ □ □ □
Ability to organize workload □ □ □ □ □ □
Ability to work independently □ □ □ □ □ □
Numerical/mathematical ability □ □ □ □ □ □
English language ability □ □ □ □ □ □
Motivation □ □ □ □ □ □
OVERALL ASSESSMENT □ □ □ □ □ □
 COMMENTS
We would appreciate your comments on the applicant’s qualifications for graduate study in the
space below. If you prefer writing with a separate recommendation letter, or need additional space,
please use official letterhead stationery and mark a cross this part.

OVERALL RECOMMENDATION

Please select one of the following:

□ I strongly recommend this applicant for the program of study
□ I recommend the applicant for the program of study
□ I do not recommend the applicant for the program of study
□ I am unable to comment

Signature Date

Thank you for completing this form. Please sign above and enclose this form in an envelope,
seal it and return it to the applicant or send directly to the address below. You may also e-mail
the signed form to [email protected].

Academic Service Office for the Medical Sciences Area

University of Tsukuba
1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan
 Graduate School of Comprehensive Human Sciences
Degree Programs in Comprehensive Human Sciences

Choose your prospective research fields from the list below and write the names in the “Prospective research fields
(supervisors)” section on the application form. You can choose up to two research fields. As a general rule, you will be
assigned to a research group during the process of selecting students for admission, so please choose carefully. It is hard to
determine the exact details of your prospective group’s research solely from the research themes listed below. In order to
avoid having to write your Master’s thesis on a research theme different from what you had in mind, please contact the
supervisor of your preferred fields or ask the contact person below for guidance about your choice.

For guidance, contact:

【Master’s Program in Medical Sciences】Irie Kenji, Chair, Master's Program in Medical Sciences, Graduate
School of Comprehensive Human Sciences, University of Tsukuba
【Master’s Program in Public Health】Wagatsuma Yukiko, Chair, Master's Program in Public Health, Graduate
School of Comprehensive Human Sciences, University of Tsukuba

Phone: 029-853-3007
FAX: 029-853-3483
E-mail: [email protected]

●Master’s Program in Medical Sciences Page.1～Page.13

●Master’s Program in Public Health Page.14～Page.15

Master’s Program in Medical Sciences

Research Area Faculty Research
Anatomy and 高橋 智 ①Elucidation of molecular mechanism of pancreatic beta
Embryology TAKAHASHI cell development and its application.
Satoru ②Functional analysis of large Maf transcription factor
family, MafB and c-Maf in macrophage development
and functions.
③Elucidating biological roles of carbohydrates using
glycosyltransferase conditional KO mice.
④Study of diseases and drug discovery by development
of novel imaging system.
⑤Elucidation of etiology and gene function in desease model
mice.

Anatomy and 武井 陽介 ①Animal model studies on synaptic dysfunction in

Neuroscience TAKEI Yosuke schizophrenia and autism.
②Cell-biological studies on synaptic dysfunction in
schizophrenia and autism.
③Studies on synaptic dysfunction caused by
inflammation.
④Studies on neuropsychiatric diseases caused by
disrupted intracellular tranbsport.

Neurobiology 志賀 隆 ①Roles of monoamines in the synapse formation

SHIGA Takashi ②Effects of environmental factors on the development of
brain and behavior
③Effects of gravitational stress on the brain
④Functional analyses of novel candidate genes involved

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 in axonal guidance
⑤Analyses of neurodegenerative diseases at a molecular
level

Diagnostic Pathology 野口 雅之 1. Study about molecular mechanisms of multistep

NOGUCHI carcinogenesis including precancerous or background
Masayuki lesions.
2. Study about molecular carcinogenesis and early
progression based on the genomic and epigenomic
abnormalities and drug development targetted the early
cancer
3. Application of fetal protein to cancer diagnosis and therapy.

Experimental 加藤 光保 ①Molecular mechanisms of stemness induction in cancer

Pathology KATO Mitsuyasu development
②Cell division kinetics of cancer stem cells by application of
live imaging and three-dimensional quantitative analysis
③Development of anti-cancer stem cell therapy using
macrocyclic peptides and antibody

Systems Neuroscience （ ） ①Brain information processing mechanism of motivation

and reward expectancy
②Research on reinforcement learning and
decision-making mechanism in the brain
③Research on information coding mechanism of reward
value in the brain
④Research on visual recognition mechanism in the brain

Cognitive and 松本 正幸 ①Roles of monoamine systems in cognitive, emotional and

behavioral MATSUMOTO motivational brain functions
Neuroscience Masayuki ②Brain mechanisms underlying value-based decision making

Neurophysiology 小金澤 禎史 ①Study on the neural regulation of the cardiovascular

KOGANEZAWA system
Tadachika ②Study on the neural regulation of the respiratory system
③Study on the neural regulation based cardiovascular and
respiratory diseases

Biochemistry , 入江 賢児 ①Post-transcriptional regulation of gene expression by

Molecular Cell Biology IRIE Kenji RNA-binding proteins
②Molecular mechanism of mRNA localization and local
translation regulating cell polarity, asymmetric cell
division, and cell-fate
③Regulation of endoplasmic reticulum stress response
④Prospore membrane formation by vesicle docking

Molecular and 小林 麻己人 ①Mechanisms underlying the formation of hematopoietic

Developmental KOBAYASHI stem cells and digestive organs
Biology Makoto ②Antioxidant mechanism of functional food ingredients
③Screen for new antioxidant food ingredients
④Zebrafish models of human diseases (e.g. CDG)

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Biochemistry , 久武 幸司 ①Molecular mechanisms of iPS cell induction
Gene Regulation HISATAKE Koji ②Mechanisms of adipocyte differentiation
③Molecular basis of epigenetics
④Chromatin modifications and transcriptional regulation

Cellular and 大林 典彦 ①Physiological functions of the small G proteins: Rab and Arf
Physiological Biology OHBAYASHI ②Membrane dynamics research aiming at
Norihiko invasion/metastasis, vascularization and pigmentation

Molecular 桝 正幸 ①Molecular studies on neural development and neural

Neurobiology MASU Masayuki circuit formation
②Molecular studies on signal transduction in the nervous
system
③Molecular studies on heparan sulfate in neural function
④Development and function of the corticospinal tract
⑤Regulatory mechanism of spinal motor nerve development

Infection Biology 川口 敦史 ①Molecular mechanism of virus replication , species

(Molecular Virology) KAWAGUCHI specificity and pathogenicity of emerging viruses
Atsushi including influenza virus
②Molecular mechanism of innate immunity

Infection Biology 森川 一也 ①Infection strategies in Gram positive pathogens

(Bacteriology) MORIKAWA ②Adaptation mechanisms of staphylococci
Kazuya ③Post-transcriptional regulation in bacteria
④Evolution of RNA regulatory networks in Enterobacteria
(Salmonella/E. coli)

Infection Biology HO, KIONG ①Understanding the mechanism of gene expression in

(Molecular protozoan parasites with a goal in identifying
Parasitology) parasite-specific processes that can be exploited as targets
for novel therapeutic interventions.
②Mechanism of mRNA recapping pathway in regulating
gene expression.
③RNA repair - understanding of the function and mechanism
behind cellular responses to RNA damage.

Immunology 渋谷 和子 ①To reveal host defense mechanisms against cancer and

SHIBUYA Kazuko infectious diseases, and to develop their therapeutic
manipulation
②To reveal cellular and molecular basis of allergy and
autoimmune diseases, and to develop their therapeutic
manipulation

Medical Genetics 野口 恵美子 ①Identification of the susceptible genes related to allergic

NOGUCHI Emiko diseases
②Genetic analysis using next generation sequencer
③Functional studies of genes involved in allergy.

Molecular and Genetic 土屋 尚之 ①Identification of genomic variants associated with

Epidemiology TSUCHIYA susceptibility and clinical characteristics of human
Naoyuki autoimmune rheumatic diseases such as systemic lupus
3
 erythematosus, ANCA associated vasculitis, systemic
sclerosis and rheumatoid arthritis.
②Molecular mechanisms of HLA and other genes associated
with autoimmune rheumatic diseases

Genome Biology 村谷 匡史 ①Integrative genome and epigenome analysis of clinical

MURATANI samples to understand mechanisms of cancer development
Masafumi and for discovery of new drug targets and biomarkers.
②Cell-free DNA and RNA profiling to monitor environmental
stress responses in internal tissues.

Regenerative Medicine 大根田 修 ①Development of Stem Cell Therapy using Mesenchymal

and Stem Cell Biology OHNEDA Osamu Stem Cells
②Functional Analysis of Hypoxia Inducible Transctiption
Factors in vivo
③Analysis of Cancer Stem Cells and Tumor Stromal Cells

Stem Cell Biology and 西村 健 ①Functional analysis of transcription factors during cell
Biotechnology NISHIMURA Ken reprogramming
②Epigenetic regulation during cell reprogramming
③Safe and efficient production of differentiated tissue cells

Laboratory Animal 杉山 文博 ①Development of new technology for producing genetically

Science SUGIYAMA modified mice.
②Development of genetically modified mice for analyzing
Fumihiro
biological function
③ Investigating the novel gene function in germ cell
maintenance and maturation.

Bioinformatics 尾崎 遼 Development of computational methods for interpreting

OZAKI Haruka massive biological data and application of bioinformatics to
biomedical problems:
(1) AI-based prediction of genome sequence functions
(2) Understanding of cell-to-cell variability thorough
single-cell omics analyses and application to disease
reasearches
(3) Investigation and prediction of functions of non-coding
regions in genome (DNA) and transcripts (RNA)
(4) Multi-omics data analyses of biological systems
(5) Data science of massive clinical data

Medical Physics 榮 武二 ①Developement of techniques for high precision proton

SAKAE Takeji therapy
②Developement of dose calculation system for neutron
capture therapy
③Application of techniques for photon therapy
④Quality assurance of radiation therapy
⑤Developement of new techniques for radiation
measurement
⑥Study for radiation protection
⑦Basic research for acquiring information of biological
function with image diagnostic techniques

4
Environmetal Biology 熊谷 嘉人 ①Adaptive response to electrophilic stress
KUMAGAI Yoshito ②Reactive sulfur species as a regulator molecule for
electrophilic stress

Molecular Biology 深水 昭吉 ① Metabolism and methylation-regulated aging and

FUKAMIZU longevity (cultured cells・C. elegans)
Akiyoshi ② Discovery of new methyltramsferases and
demethyltramsferases, and its biological significance (cells・
C. elegans・genetic model mice)

Developmental 丹羽 隆介 ①Studeis on interorgan communications for germline stem

Gentics NIWA Ryusuke cell proliferation and maintenance.
②Studeis on interorgan communications for regulating aging
process
③Chemical biology for developing pesticides

Biomaterials Science 長崎 幸夫 ①Design of Nanomedicine

NAGASAKI Yukio ②Design of Drug Delivery System
③Design of Materials for Degenerative Medicine
④Design of Biointerfaces

Neuroscience 柳沢 正史 Our lab aims at solving the mystery of sleep

YANAGISAWA ①Elucidation of the molecular mechanism regulating
Masashi sleep/wakefulness through a forward genetic approach
②Medicinal chemistry to develop new drug for sleep disorder
③Visualization of neural and glial cell activity during
sleep/wakefulness behavior

Medicinal Chemistry / 沓村 憲樹 ・Orexin receptor selective agonist/antagonist

Organic Synthetic KUTSUMURA ・Opioid receptor selective agonist/antagonist
Chemistry/ Noriki Through development such ligands shown above, we aim to
Neuropharmacology create narcolepsy therapeutics, analgesics, and
antidepressants, etc. Not only synthesis of compounds but
also pharmacological evaluation (in vitro and in vivo) are
performed.
New drug creation by clarification of plasticity in the central
nervous system and change of emotional brain function
induced by stress, chronic pain and drugs of abuse.

Molecular Behavioral 櫻井 武 ①Elucidation of physiological roles of novel neuropeptide

Physiology SAKURAI Takeshi ②Revealing the neural circuits and neural mechanisms that work in
the system that regulates emotion.
③Studies on the neural circuits and neural mechanisms that play roles
in the regulation of sleep/wakefulnesss states.
④Elucidation of neural circuits and mechanisms by which body
temperature and metabolisms are regulated.

Functional sleep 坂口 昌徳 ①Function of sleep in memory consolidation.

science SAKAGUCHI Correlation of brain plasticity and sleep
Masanori ②Function of sleep in processing traumatic memory
http://iiis.php.xdomain.jp/sakaguchi/www/
5
Brain maturation/ （ ） ①Elucidation of the function of sleep focusing on brain
evolution maturation and aging
②Elucidation of the evolutionary process of sleep based on
molecular and developmental approaches

Systems LAZARUS Michael ① Understanding the control of sleep and wake by motivation
Pharmacology ② Sleep circuits as potential therapeutic targets for insomnia
③ Link between REM sleep loss and the desire for junk food
④ Elucidation of neural mechanisms of short-sleep
⑤ Analysis of the effects of short-sleep on physiological functions

Molecular Circuits of LIU, Qinghua ①Comprehensive understainding of the molecular and

RNAi, Sleep, and Fear neural bases for sleep drive
②Elucidation of the molecular and neural bases for fear and
sexual behaviors

Electrophysiology and 本城 咲季子 ①The dynamics of thalamocortical system across sleep/wake

molecular biology of HONJOH Sakiko cycles
sleep ② Elucidation of neural circuits underlying NREM sleep
specific EEG patterns
③Analysis of vigilance state-depedent transcriptional
changes
④Elucidation of the function of vigilance-state specific genes
in neural activity

Occupational 松崎 一葉 ①A study of the strong qualities unexpectedly in space

psychiatry/Space MATSUZAKI ②Salutogenesis and Sense of coherence
psychiatry Ichiyo ③Nature based Rehabilitation

Vascular Matrix 柳沢 裕美 ①Identification and functional analysis of novel extracellular

Biology YANAGISAWA matrix proteins in the vessel wall
(TARA Center) Hiromi ②Molecular mechanism of aortic aneurysm formation and
rupture
③Mechanotransduction in the vessel wall
④Characterization of niche matrix associated with epidermal stem
cells

Nephrology 山縣 邦弘 ①Mechanism of chronic progressive kidney diseases

YAMAGATA ②Method of early diagnosis and prevention of kidney
Kunihiro diaseases
③Approach to treatment of progressive kidney diseases
④Epidemiology of acute kidney injury and chronic kidney
disease
⑤Outcome research of lifestyle diseases

Clinical Immunology （ ） 1) Molecular mechamism in autoimmunediseases such as

and Rheumatology rheumatoid arthritis and connective tissue diseases
2) Specific regulation of autoimmune diseases
3) Approarch to gentic therapy and disease-specific iPS cells
therapy in autoimmune diseases

6
Hematology 千葉 滋 ①Mechanism of leukemo/lymphomagenesis
CHIBA Shigeru ②Mechanism of bone marrow failure
③Translational research on stem cell therapy
④Laboratory hematology for hematopoietic disorders

Medical Oncology （ ） ①Basic and clinical research on medical oncology

and Gastroenterology ②Development of molecular targeted agent and novel
therapy

Pulmonary Medicine 檜澤 伸之 ①Molecular genetics of chronic inflammatory lung diseases

HIZAWA including asthma and COPD
Nobuyuki ②Role of genetics and environmental factors in allergic
diseases
③Study of interactions between genetics and environment in
respiratory diseases

佐藤 浩昭 ①Study of chemotherapy for lung cancer

SATOH Hiroaki ②Clinical application of carbohydrate antigens for
respiratory diseases
③Optimal therapeutic strategy development for lung cancer
in the elderly

Pulmonary medicine, 石井 幸雄 ①Elucidation of cellular and molecular mechanisms of

infection, and allergy ISHII Yukio pulmonary host responses to environmental stimuli,
including cigarette smoke, antigens, chemical carcinogens,
and microorganisms.
②Exploring the bio-markers in inflammatory and allergic
lung diseases.

Cardiology 家田 真樹 ①Cardiac regeneration and translational research

IEDA Masaki ②Reprogramming to generate cardiomyocytes
③Molecular mechanism and new therapy for cardiovascular
diseases

宮内 卓 ①Establishment of mechanism and treatment of arrhythmia

小池 朗 ②Establishment of evaluation of hemodynamics
本間 覚 ③Establishment of new treatment strategy of heart failure
MIYAUCHI ④Relation between arteriosclerosis and endothelial function
Takashi ⑤Exercise physiology and cardiac rehabilitation in cardiac
KOIKE Akira patients
HONMA Satoshi ⑥Medical quality assurance and risk management

Metabolism and 島野 仁 ①Molecular mechanism of obesity, diabetes, dyslipidemia,

Endocrinology SHIMANO Hitoshi and atherosclerosis
②Physiology and pathophysiology of transcription factors
involved in the metabolism of carbohydrate and lipid
③Sensing mechanism and transcriptional regulation of
energy metabolism
④Hub-metabolites and epigenetic regulation in
carbohydrate, lipid, and protein metabolism
⑤Quality aspect of fatty acids and physiology and

7
 pathophysiology of various organs
⑥Molecular visualization at organella level and synthetic
biology
⑦Inhibition of cholesterol synthesis, myopathy, and brain
dysfunction
⑧Fatty acid metabolism in stem cell

Lipid Medicine 松坂 賢 ①Elucidation of the role of fatty acid elongase Elovl6 in

MATSUZAKA lifestyle-related diseases
Takashi ②Elucidation of the role of Elovl6 in the development and
function of brain
③Elucidation of the role of Elovl6 in cancer
④ Examination of the effect of Elovl6 inhibition in rare
diseases caused by lipid accumulation
⑤Crystal structure analysis of Elovl6
⑥Development of the new Elovl6 inhibitor

Infectious Diseases （ ） 1. Epidemiological investigation of serious infectious diseases

and HIV infection.
2. Molecular investigation of pathogenic and drug-resistant
factors of microorganisms.
3. Evaluation of precautions against transmissible infections
diseases.
4. Clinical studies among patients with infectious diseases

Neurology （ ） ①Molecular pathogenesis of Alzheimer’s disease

②Pathology and biochemistry of neuromuscular disorders
③Neurobiology of neurodegenerative disorders
④Neuro-ophthalmology of neurological disorders
⑤Clinical and epidemiological studies of organoarsenic
intoxication

General Thoracic 佐藤 幸夫 This course is programmed to investigate on

Surgery SATOH Yukio 1) minimal invasive thoracoscopic surgery for lung cancer, 2)
angiogenesis and invasion of lung cancer, 3)
leukocytes-endothelial interaction in acute lung injury, 4)
novel sealant material for surgery, 5) screening of lung cancer
with exhaled breath and 6) surgical simulation, and
estimation of postoperative lung regeneration and function
using 3D-CT.

Cardiovascular 平松 祐司 ①Development of novel microangiography system using

Surgery HIRAMATSU Yuji synchrotron radiation
②Elucidation of signal transduction in aneurysmal formation
③Elucidation of hematological deterioration during
cardiopulmonary bypass
④Study of ischemic myocardial remodeling using knockout
mice
⑤Development of novel tissue crosslinking treatment
technology
⑥Development of vitamin K-reduced functional food
⑦Development of valve simulation technology
8
 ⑧Exploration of valve-sparing right ventricular outflow
reconstruction
⑨Study in rehabilitation medicine in reduced venous return
⑩Regulation of gaseous microemboli in cardiopulmonary
bypass
⑪Regenerative medicine using stem cells
⑫Production of 3D heart replicas

Pediatric Surgery 増本 幸二 ①Bioengineered tissue transfer in infants and children

MASUMOTO Koji ②Studies related to carcinogenesis and progression of
malignant solid tumors in children
③Pathological, molecular biological and genetic studies of the
alimentary tract malformations
④Studies of treatment for hypoplastic lungs in congenital
diaphragmatic hernia

Organ （ ） 1) Platelet and regenerative medicine: To clarify the

Transplantation, mechanisms of liver regeneration by platelet function and
Gastroenterological aging platelet.
and Hepatobiliary 2) Drug delivery system：To investigate the mechanisms of
Surgery liver injury and to develop a method of prevention by the
use of a novel DDS.
3) Surgical metabolism and wound healing: To develop a
novel treatment for minimizing intestinal damage under
surgical stress.
4) Multipotential stem cells and regenerative medicine: To
develop a gastroenterological tissue or organ bud in
micro-environment with placental or/and other tissue
derived
stem cells for transplantation trials.
5) CancerComprehensive elucidation of cancer genesis and
metastasis by analyzing cancer stem cells, local
microenvironment (incl. fibroblast and platelets), and
niche in metastatic site (liver Kuppfer cells, platelets).
Paying special interest on cancer specific glyco-proteins,
which will confer bran-new therapeutic strategy that
specifically target cancers by glycan-lectin interaction:
6) Computer assisted Surgery (CAS): To develop and apply
the system of the CAS and the novel surgical education
system through the medical-engineering collaboration.

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Neurosurgery 松丸 祐司 1) Neurooncology
MATSUMARU 1)-1 Neurooncology(Advanced Therapeutics): Boron neutron
Yuji capture therapy(BNCT), Proton therapy, Tumor
vaccination, Gene thrapy, Photodynamic diagnosis and
treatment (PDD, PDT)
1)-2 Neurooncology(Diagnostics): Molecular maker and gene
analysis of brain tumor(glioma, pediatric brain tumor,
craniopharyngioma), Intraoperative neurophysiological
monitoring (MEP, SEP, EEG), Imaging
study(Intraoperative MRI, Tractography, PET)
2) Cerebrovascular disease: Neuroprotection using
nanoparticle and stem cell therapy for ischemic stroke.
Prevention of carotid artery restenosis. Evaluation of
oxidative stress in brain. Regenerative Medicine using
dental pulp stem cells
3) Analysis of cerebral function, perfusion and metabolism
using neuroimaging (functional -MRI, MR spectroscopy,
diffusion tensor imaging, PET)
4) Neurorehabilitation using Robot Suit HAL, Brain
machine interface
5) Functional neurosurgery for epilepsy, involuntary
movement, central pain and Headache
6) Gene therapy and regeneration therapy using DDS
(Angiogenesis, bone regeneration)
7)Pediatric Neurosurgery: Epigenetic biomarkers from
woman with neural tube defect affected pregnancies
8）Development of advanced medical equipment and device
(laser endoscope, new device of endoscopic surgery)
9) Neuroendovascular Therapy: Development of new devices,
functional neurovascular anatomy, Outcome research of
neuroendovascular therapy

Control of the 山崎 正志 Clinical and basic research on following themes:

Musculoskeletal YAMAZAKI ①Treatment of spinal disorders
System Masashi ②Treatment of joint disorders
③Sports medicine
④Regeneration of peripheral nerve
⑤Functional improvement treatment using Robot suit HAL
for muscloskeletal disorders

Urology 西山 博之 ①Cancers of genitourinary system

NISHIYAMA ②Urodynamics
Hiroyuki ③Andrology
④Urolithiasis
⑤Urinary tract infection

Ophthalmology 大鹿 哲郎 ①Visual science

OSHIKA Tetsuro ②Visual optics
③Minimally invasive ocular surgery
④Vision-related quality of life
⑤Development of artificial vitreous
⑥Development of new generation of OCT

Otology & Equilibrium （ ） Study on theories and methods for

Research pathophysiological, electrophysiological and

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 biochemical research in otology and
cochleoneural path way.

Oral and 武川 寛樹 ①New development of biological marker for oral cancer (p63
Maxillofacial Surgery BUKAWA Hiroki and GNT-V)
②Research for clinical diagnosis and treatment of oral cancer
using microRNA (miR203, miR155, miR205 and let-7)
③Regenerated research using dental pulp stem cell
④Research for oral bacterial flora involved internal medical
disease (NASH, NAFLD and diabetes mellitus)

Psychiatry 新井 哲明 ①Neuropathology of dementia and neurodegenerative

ARAI Tesuaki disorder
②Clinical study of diagnosis, therapeutics, prevention and
care of dementia
③Geriatric psychiatry
④Neuroimaging of neuropschyatric disorders
⑤Transdisciplinary team approach for psychiatry

Pediatrics 高田 英俊 ①Development of new gene therapy for genetic disorders of

TAKADA childhood using new Sendai virus vector
Hidetoshi ②Immunological analysis of host factor in children who
developed vaccination-related adverse reaction
③Analysis of the characteristics of immune reaction of
fetuses and neonatates
④Nation-wide analysis of child disorders including primary
immunodeficiencies
⑤Long term analysis of therapeutic effect of childhood cancer
⑥New objective analysis of the development of children

Obstetrics and 濱田 洋実 Basic and clinical researches about diagnosis, treatment, and
Gynecology HAMADA Hiromi prevention of diseases/disorders in the field of obstetrics and
gynecology are conducted. Major subjects are gynecological
malignancy, infertility, reproductive endocrinologic disorder,
fetal genetic disease/malformation, fetomaternal infection,
maternal, natal, and puerperal complications, etc.

Radiation Oncology 櫻井 英幸 ①Research for radiosensitivity, and improvement of

SAKURAI radioresistance
Hideyuki ②Radiation treatment planning using multimodality
imaging
③New cancer therapy using particle radiation therapy

Radiation Health Risk 磯辺 智範 ①Environmental radiation (distribution of radiation in soil,

Science ISOBE Tomonori river, sea, crops and wildlife)
②Radiation exposure evaluation
③Soil and surface decontamination technology
④Dose Evaluation and Radiation Protection Technique of
Medical Radiation Exposure to Eye Lens
⑤Dose evaluation of neutron exposure in radiotherapy
⑥Technical development on radiation disasters

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Anesthesiology 田中 誠 ①Effects of anesthetics and anesthetic techniques on arterial
TANAKA Makoto baroreflex function
②Genetic polymorphism of opioid receptor in humans
③Research on basic mechanisms of pain perception
④Effects of anesthetics and age on Bispectral Index

Clinical laboratory 川上 康 ①Molecular understanding of the endocrine tumor and

medicine KAWAKAMI apoprotein.
Yasushi ②Molecular analysis of the cell proliferating factor.
③Molecular understanding of the hormone synthesis and
secretion.

Molecular Sportology 正田 純一 ①Development of novel exercise training for obese subjects

SHODA Junichi with life style-related diseases
②Imaging analysis of organ lipid accumulation in obese
subjects with life style-related diseases
③Development of glycobiomarkers for obesity and life
style-related diseases
④Development of novel animal models for obesity and life
style-related diseases
⑤Exercise-induced activation of antioxidative streass
systems
⑥Understanding of exercise-induced inhibitory mechanism
against carcinogenesis

竹越 一博 ①Personalized treatment for exercise through using genetic

TAKEKOSHI infomation
Kazuhiro ②Research for anti-doping
③Exercise and hormone, especially catecholamine
④Exercise and stress marker, especially salivary
Chromogranin A (collaborated with Prof. Omori)

Pharmaceutical 本間 真人 ①Gene Polymorphism analysis for assessing drug

Sciences HONMA Masato metabolizing enzymes and transporters
②Therapeutic drug monitoring for assessing drug efficacy
and adverse reactions.
③Pharamcokinetic analysis of Kampo-medicine (Japanese
herbal remedies)

Emergency and 井上 貴昭 ①Physiology of septic shock and shock

Critical Care INOUE Yoshiaki ②Physiology of acute respiratory distress syndrome and
Medicine multiple organ failure
③Physiology of Post cardiac arrest syndrome
④Scientific approach for post intensive care syndrome and
delilium

Clinical and 橋本 幸一 ①Regulatory science

Translational Research HASHIMOTO ②Clinical trilas for functional foods
Methodology Koichi ③Improvement of efficiency of practical medicine using AI
and IOT
④Construction of seamless platform for translational
research
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 ⑤Education of experts of integrative celerity research
process for translational researches

Clinical Research and 松阪 諭 ①Development of clinical decision system (Liquid biopsy

Regional Innovation MATSUSAKA analysis) for cancer chemotherapy
Satoshi ②Understanding the mechanisms of cancer metastasis and
anticancer agent resistance
③Functional studies of Organoids with Cancer Stem Cell-like
Properties

Primary Care and 前野 哲博 ①Clinical research in primary care

Medical Education MAENO Tetsuhiro ②Development of community-based medical System
③Health promotion in the community
④Clinical medical education

Forensic Medicine 本田 克也 ①Research on forensic DNA testimg

HONDA Katsuya ②Mitochondorial DNA polymorphism
③Studies on the toxicological mechanism of xenobiotics
④Research of molecular autopsy on sudden unexpected death

Medical Science and 柳 久子 ①Preventive medicine for non-communicable diseases and

Welfare YANAGI Hisako frailty, Medical welfare for elderly
②Genetic counselling, Bioethics

Integrated Study on 大庭 良介 ①Science, Technology and Society (Health, Food, Life,

Health Information OHNIWA Ryosuke Science history, etc.)
②Science communication (Health, Food, Life, etc.)
③Prototype development (Nutrition education materials,
Food recipe, etc.)
④Application of microbial and natural resources
⑤Methodology study (Science, East Asian Traditional
Philosophy, Kampo, etc.)

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Master’s Program in Public Health
Research Area Faculty Research
Occupational 松崎 一葉 ①A study of the strong qualities unexpectedly in space
psychiatry/Space MATSUZAKI ②Salutogenesis and Sense of coherence
psychiatry Ichiyo ③Nature based Rehabilitation

Primary Care and 前野 哲博 ①Clinical research in primary care

Medical Education MAENO ②Development of community-based medical System
Tetsuhiro ③Health promotion in the community
④Clinical medical education

International 安梅 勅江 ①Community empowerment

Community Care and ANME Tokie ②Plasticity of lifespan development and implications
Lifespan ③System sciences for health social services
Development：
Empowerment
Sciences
Gerontological 橋爪 祐美 ①Gender issues and Japanese family
Nursing & Caring HASHIZUME caregiving, Interpersonal support for the middle-aged couple
Yumi ②Toyamagata day service
③Community care and formal caregivers, care for the family
caregivers
④Community care in Mongolia
⑤Family caregiving by foreign bride and Japanese husband
⑥Qualitative research method (Grounded theory approach) ,
mixed method

Health Services 田宮 菜奈子 ①Health Services Research (clinical medicine, long-term care,
Research TAMIYA Nanako prevention services)
②Cooperation of medical care and welfare in the local
community
③Policy evaluation of the long-term care insurance system
④Study for the improvement of the quality of in-home care
and facility care for older people and people with disability
⑤Public Health based on legal medicine (older people, child
abuse, solitary death, actual state of service-related death,
etc.)

Epidemiology 我妻 ゆき子 ①Principles and methods in epidemiology and their

WAGATSUMA applications
Yukiko ②Medical statistics and medical information science
③Epidemiology for diseases
④Sociological survey in the field of medicine
⑤Methods of clinical trials
⑥Strategy to control diseases in developing countries

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Social Psychiatry & 斎藤 環 ①Asocial problem behaviors in childhood and adolescence
Mental Health SAITO Tamaki ②Development disorder and maladaptation
③Rehabilitation of people with mental disorder
④Dialogical practice (Open Dialogue)
森田 展彰 ①Mental health of victims, Psychotherapy
MORITA Nobuaki ②Intervention and treatment for family violence
(Child abuse, Domestic violence, alder abuse and parent
abuse by children)
③Recovery of addiction (Substance use disorder, gambling
disorder and internet dependence)
④Forensic psychiatry, Criminology

Forensic Medicine 本田 克也 ①Research on forensic DNA testimg

HONDA Katsuya ②Mitochondorial DNA polymorphism
③Studies on the toxicological mechanism of xenobiotics
④Research of molecular autopsy on sudden unexpected death

Global Public Health 市川 政雄 ①Global health research

ICHIKAWA ②Community design & health
Masao ③Injury prevention & control

Medical Science and 柳 久子 ①Preventive medicine for non-communicable diseases and

Welfare YANAGI Hisako frailty, Medical welfare for elderly
②Genetic counselling, Bioethics

Health care policy 近藤 正英 ①Application of economics for health care

and KONDO ②Health care policy research
Health economics Masahide ③Global health economics

Livelihood Support 徳田 克己 ①Child care and guardians’ support

Science TOKUDA ②Beggars with disabilities
Katsumi ③Cemetery, graves and tombs

水野 智美 ①Barrier-free
MIZUNO Tomomi ②Child care and guardians’ support
③Understanding persons with special needs

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