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MCQ Bio

The document contains multiple choice questions about various topics in bioinformatics including sequence alignment algorithms, genomic concepts, and database tools. BLAST is identified as the fastest program for searching similar sequences in databases. The Needleman-Wunsch algorithm is used for pairwise sequence alignment. Application of bioinformatics includes data storage/management, drug design, and understanding relationships between organisms.

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Supriyo Chatterjee
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356 views6 pages

MCQ Bio

The document contains multiple choice questions about various topics in bioinformatics including sequence alignment algorithms, genomic concepts, and database tools. BLAST is identified as the fastest program for searching similar sequences in databases. The Needleman-Wunsch algorithm is used for pairwise sequence alignment. Application of bioinformatics includes data storage/management, drug design, and understanding relationships between organisms.

Uploaded by

Supriyo Chatterjee
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOCX, PDF, TXT or read online on Scribd
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Which of the following is the fastest program to search for similar sequences in databases?

(A) BLAST

(B) FASTA

(C) Needleman-Wunsch

(D) Smith-Waterman

Human body Nucleotide base-pair distances summed up which is equal to (1AU=Distance from Sun to
Earth)

(A) 30AU (B) 60AU

(C) 120AU (D) 200AU

Which of the following sequence is correct?

(A) DNA, RNA, Protein (B) DNA, Protein, RNA

(C) RNA, DNA, Protein (D) None of these

Which one of the following is the appropriate tool for a description of a sequence line with the symbol >

(A) FASTA (B) BLAST

(C) MMD (D) None of these

Data archival means

(A) Storage of data (B) Analyzing data

(C) Retrieving data (D) Removal of data


Excessive uric acid causes which disease?

(A) Corona-fever (B) Dengue-fever

(C) Gout (D) Cancer

Which one of the following does not match with the rest three?

(A) PDB (B) NCBI

(C) EMBL (D) ORF

Needleman Wunch algorithm is used for

(A) single alignment pair

(B) pairwise sequence alignment

(C) multiple alignment

(D) all of these

The process of finding relative location of genes on chromosome is called

(A) gene tracing (B) genome mapping

(C) genome walking (D) chromosome walking

Biologically significant similar sequences have

(A) Higher E-value (B) Lower E-value

(C) Lower raw score (D) Lower bit score

Hamming or edit distance for following two given words is


MIDDLE

RIDDLE

(A) 2 (B) 0

(C) 5 (D) none of these

Similar sequences in two different organisms that have

been derived from a common ancestor sequence is

(A) Homologs (B) Orthologs

(C) Paralogs (D) Xenologs

Total Number of Useful Amino Acids are

(A) 23

(B) 20

(C) 19

(D) None of these

Pairwise Alignment includes

(A) Local (B) Global

(C) Both (A) and (B) (D) None of these

Human Genome contains about

(A) 2 billion base pairs

(B) 3 billion base pairs

(C) 4 billion base pairs

(D) 6 billion base pairs


A single piece of information in a database is called

(A) File

(B) Field

(C) Record

(D) Data set

Phylogenetic relationship can be shown by

(A) Dendogram

(B) Gene Bank

(C) Data retrieving tool

(D) Data search tool

Application of bioinformatics include

(A) Data storage and management

(B) Drug designing

(C) Understand relationships between organisms

(D) All of the above

Proteomics is the study of

(A) Set of proteins

(B) Set of proteins in a specific region of the cell

(C) Entire set of expressed proteins in a cell

(D) None of these


The first bioinformatics database was created by

(A) Richard Durbin

(B) Dayhoff

(C) Michael j.Dunn

(D) Pearson

When you are comparing two or more than two sequences of same or different organisms, what is the
type of the alignment?

(A) Global

(B) Pairwise Sequence

(C) Local

(D) Multiple Sequence

Who developed PAM matrices and in which year?

(A) Needleman and Wunsch, 1976

(B) Smith-Waterman, 1978

(C) Dayhoff et al., 1978

(D) Henikoff 1992

There are ____ possible stop codons, identification of which is straightforward.

(A) five

(B) two

(C) ten

(D) three
Screening the predicted protein sequences against ______ library confirms the prediction and
expression of the gene.

(A) expressed sequence tag (EST)

(B) tags

(C) palindromes

(D) proteomes

Gene identification in prokaryotic organisms is simplified by their lacking _____

(A) exons

(B) introns

(C) coding segments

(D) useful nucleotide sequences

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