Drug Classification Action of Drug Indication and Contraindication Side Effect Nursing Consideration

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DRUG CLASSIFICATION ACTION OF DRUG INDICATION AND SIDE EFFECT NURSING CONSIDERATION

CONTRAINDICATION
Brand name: Promethazine Pharmacologic Class: Selectively blocks the H Indication: CNS: Dizziness, drowsiness, Before
HCI Phenothiazine receptors, diminishing the - Prevention and treatment poor coordination, confusion, -Observe 15 rights in drug
effects of histamine on cells of nausea and vomiting restlessness, excitation, seizures, administration.
Generic name: Phenergan Therapeutic Class: of the upper respiratory associated with labyrinthitis tremors headache, blurred vision, - Assess for hypersensitivity
Antiemetic Antihistamine, tract and eyes and - Prevention of motion diplopia, vertigo, tinnitus and other contraindications.
Ordered Dose: 125 mg q 4- Sedative, Hypnotic decreasing the sneezing, sickness - Reduce dosage for patients
6 hrsprnnausea mucus production, itching - Short-term management of CV: Hypotension, with hepatic impairment.
Pregnancy Risk Factor: с and tearing that accompany insomnia palpitations bradycardia, tachycardia. - Reduce dosage of
allergic reactions in - Symptomatic relief of extrasystoles barbiturates given concurrently
sensitized people exposed perennial and seasonal with promethazine by at least a
to antigens; blocks allergic rhinitis, allergic Dermatologic: Urticaria, half.
cholinergic receptors in the conjunctivitis. rash, photosensitivity, chills - Arrange for dosage reduction
vomiting centre that are uncomplicated urticaria and of opioid analgesics given
believed to mediate the angioedema GI: Epigastric distress concomitantly by one fourth to
nausea and vomiting caused - Amelioration of allergic nausea, vomiting, diarrhea, one-half.
by gastric irritation, by reactions to blood or plasma constipation
input from the vestibular - Dermatographism During
apparatus, and by input adjunctive therapy in GU: Urinary frequency - Do not give tablets or rectal
from the chemoreceptor anaphylactic reactions dysuria, urinary retention, decreased suppositories to children
trigger zone; depresses the - Preoperative postoperative, libido, impotence younger than 2 yr.
RAS, including the parts of or obstetric sedation - Give IM injections deep into
the brain involved with - Adjunct to analgesics to Hematologic: Hemolytic muscle
wakefulness. control postoperative pain anemia, hypoplastic anemia, - Do not administer
- Adjunctive IV therapy with thrombocytopenia.leukopenia, subcutaneously, tissue necrosis
reduced amounts of agranulocytosis, pancytopenia may occur.
meperidine or other opioid - Do not administer
analgesics in special surgical intrarterially: arteriospasm and
conditions gangrene of the limb may result
- Instruct to take drug exactly
Contraindications: as prescribed.
-Hypersensitivity to
antihistamines or After
phenothiazines - Instruct to avoid alcohol.
- Comatose patients - Severe - Instruct to avoid driving or
CNS depression engaging in other dangerous
- B * o * r marrow activities of dizziness,
depression - Vomiting of drowsiness or vision changes
unknown cause - occur.
Concomitant therapy with - Educate about avoiding
MAOI's prolonged exposure to the sun,
or using of sunscreen or
covering garments.
- Maintain fluid intake, use
precautions against heatstroke
in hot weather. Report sore
throat, fever, unusual bleeding
or bruising, rash, fever,
weakness, tremors, impaired
vision, dark urine, pale stools,
yellowing of the skin or eyes.

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