DRUG STUDY

Name of Drug Classification Mechanism of Action Indication Contraindication Side Effects

Generic Name: Pharmacologic Class: This drug blocks activity of  For relief of pain 1. Hypersensitivity to drug, CNS
Ibuprofen Nonsteroidal anti-inflammatory cyclooxygenase, the enzyme associated with aspirin, iodides, or other 1. Headache
drug (NSAID), propionic acid needed to synthesize rheumatoid arthritis, NSAIDs 2. Dizziness
Trade/Brand Name: derivative prostaglandins, which mediate osteoarthritis, and 3. Drowsiness
Advil, Motrin inflammatory response and juvenile arthritis 2. Perioperative use in 4. Nervousness
Therapeutic Class: cause local pain, swelling, and coronary artery bypass graft 5. Aseptic meningitis
Analgesic, antipyretic, anti- vasodilation. By inhibiting  For relief of mild to surgery
inflammatory prostaglandins, this NSAID moderate pain CV
3. Pediatric heart surgery
reduces inflammatory 1. Hypertension
 For pain relief in (before and after)
Pregnancy Risk: symptoms and relieves pain. 2. Arrhythmias
primary dysmenorrhea
Category C (first & second Ibuprofen’s antipyretic action 4. Pregnant women starting
trimesters), Category D (third probably stems from its effect  For fever reduction at 30 wk gestation EENT
trimester) on the hypothalamus, which (premature closure of the 1. Amblyopia
increases peripheral blood  For relief of moderate ductus arteriosus) 2. Blurred vision
flow, causing vasodilation and to severe pain as an 3. Tinnitus
Sources: encouraging heat dissipation. adjunct to opioid 5. Patients with recent MI or
Jones & bartlett learning 2018 analgesics severe heart failure GI
nurse’s drug handbook (7th ed.). 1. Nausea
(2018). Jones & Bartlett Sources:  For treatment of Precautions 2. Vomiting
Learning. Jones & bartlett learning 2018 patent ductus arteriosus Use with extreme caution in 3. Constipation
nurse’s drug handbook (7th ed.). patients with: 4. Dyspepsia
Kizior, R.J. & Hodgson, K.J. (2018). Jones & Bartlett 5. Abdominal discomfort
(2019). Saunders nursing drug Learning. Sources: 1. History of GI bleeding or 6. GI bleeding
handbook 2019 (27th ed.). Jones & bartlett learning ulcer disease
Elsevier. Kizior, R.J. & Hodgson, K.J. 2018 GU
(2019). Saunders nursing drug nurse’s drug handbook (7th 2. Hypertension 1. Cystitis
Skidmore-Roth, L. (2019). handbook 2019 (27th ed.). ed.).
Mosby’s 2019 nursing drug 2. Hematuria
Elsevier. (2018). Jones & Bartlett 3. Advanced age (elderly
reference (32nd ed.). Elsevier. 3. Azotemia
Learning. patients)
4. Renal failure
Skidmore-Roth, L. (2019).
Vallerand, A.H. & Sanoski, Mosby’s 2019 nursing drug Kizior, R.J. & Hodgson, K.J. 4. Long-term ibuprofen
C.A. (2019). Davis’s drug guide reference (32nd ed.). Elsevier. therapy Hematologic
(2019). Saunders nursing
for nurses (16th ed.). F.A. Davis drug 1. Anemia
Company. Vallerand, A.H. & Sanoski, handbook 2019 (27th ed.). 2. Prolonged bleeding time
C.A. (2019). Davis’s drug guide Elsevier. Sources: 3. Aplastic anemia
for nurses (16th ed.). F.A. Davis Jones & bartlett learning 2018 4. Neutropenia
Company. Skidmore-Roth, L. (2019). nurse’s drug handbook (7th 5. Pancytopenia
Mosby’s 2019 nursing drug ed.). 6. Thrombocytopenia
7. Leukopenia
reference (32nd ed.). Elsevier. (2018). Jones & Bartlett 8. Agranulocytosis
Learning.
Vallerand, A.H. & Sanoski, Hepatic
C.A. (2019). Davis’s drug Kizior, R.J. & Hodgson, K.J. 1. Hepatitis
guide for nurses (16th ed.). (2019). Saunders nursing drug
F.A. Davis Company. handbook 2019 (27th ed.). ENDO
Elsevier. 1. Hyperglycemia
2. Hypoglycemia
Skidmore-Roth, L. (2019).
Mosby’s 2019 nursing drug
Respiratory
reference (32nd ed.). Elsevier.
1. Bronchospasm
Vallerand, A.H. & Sanoski,
C.A. (2019). Davis’s drug Skin
guide for nurses (16th ed.). 1. Rash
F.A. Davis Company. 2. Pruritus
3. Urticaria
4. Stevens-Johnson syndrome

Other
1. Edema
2. Allergic reactions including
anaphylaxis

Sources:
Jones & bartlett learning 2018
nurse’s drug handbook (7th ed.).
(2018). Jones & Bartlett
Learning.

Kizior, R.J. & Hodgson, K.J.

Skidmore-Roth, L. (2019).
Mosby’s 2019 nursing drug
reference (32nd ed.). Elsevier.

Vallerand, A.H. & Sanoski,