SLR-VC-47

Seat
No.
Set P
M.Sc. (Semester - I) (CBCS) Examination Nov/Dec-2018
Bioinformatics
BASIC BIOINFORMATICS
Time: 2½ Hours Max. Marks: 70
Instructions: All questions are compulsory.
Q.1 Multiple choice Questions:- 14
1) ________ database is a Microarray gene expression database studying in
bioinformatics.
a) GEO b) MMDB
c) DDBJ d) EMBL
2) ____________ is a graphical control element that presents a hierarchical
view of information of phylogentic analysis.
a) Diagonal view b) Alignment view
c) Tree view d) Domain view
3) The delta rule is often utilized by the most common class of ANNs called
_________ neural networks.
a) classification b) backpropagational
c) unidirectional d) feed forward
4) Clustal w is a ____________ multiple alignment program available either as
a stand-alone or on-line program.
a) exhaustive b) block based
c) progressive d) iterative
5) ________ is branch of which study the organismal variation in phenotype as
it changes during its life span.
a) Phenomics b) Metabolomics
c) Transcriptomics d) Genomics
6) _______ database only contains sequence families not covered in Pfam-A.
a) Prosite b) PIR
c) pfam b d) Blocks
7) __________ Markov model describes the probability of the current state being
determined by the previous state.
a) First-order b) Second-order
c) Third-order d) Zero-order
8) __________ is molecular biology database and text data along with sequence
data retrieval system developed by NCBI.
a) Dbget b) dblink
c) Entrez d) Srs
9) _________ is a database that uses multiple alignments derived from the most
conserved, ungapped regions of homologous protein sequences.
a) Emotif b) Blocks
c) Smart d) Cath
10) In a protein sequence alignment, _________ refers to the percentage of
matches of the same amino acid residues between two aligned sequences.
a) sequence identity b) sequence homology
c) sequence similarity d) sequence non homology

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 SLR-VC-47
11) __________ alignment does not assume that the two sequences in question
have similarity over the entire length.
a) Local b) Global
c) Heuristic d) Clustal
12) The _______ is a global network of computer networks that links
government, academic and business information.
a) FTP b) Gmail
c) Telenet d) Internet
13) The scoring systems is called a _________ which is derived from statistical
analysis of residue substitution data from sets of reliable alignments of highly
related sequences.
a) substitution matrix b) sequence alignment
c) sequence identity d) sequence homology
14) The term sequence _______ which is the similar at same position of same
amino acid along with similar in physiochemical properties such as size,
charge, and hydrophobicity.
a) identity b) similarity
c) homology d) xenology
Q.2 A) Answer any four of the following 08
1) What is interactomics?
2) What is guide tree in phylogentics analysis?
3) What is sequence identity in string matching algorithm?
4) What is local alignment in sequence analysis?
5) What is BanKit in Genbank nucleotide sequence database?
B) write notes on (Any Two) 06
1) Write the steps of system biology in study of associated disciplines.
2) Explain the PAM scoring matrix in dynamic programming algorithm.
3) Explain the Entrez search engine in data mining.
Q.3 A) Answer the following (Any Two) 08
1) Explain ANN in bioinformatics for analysis the biological data.
2) Explain the BLAST tool at NCBI in details.
3) Explain the Protein Information resources sequence database.
B) Answer the following:- (Any One) 06
1) Explain multiple sequence alignment and its type in details.
2) Write in details about the application of neural network in bioinformatics.
Q.4 A) Answer the following (Any Two) 10
1) Explain the Phylip software Package in details.
2) Explain protein secondary sequence database in details.
3) Write the Gene array and analysis of gene array in bioinformatics in
details.
B) Answer the following:- (Any One) 04
1) Write EMBL nucleotide sequence database in details.
2) Explain the support vector machine in machine learning technique.
Q.5 Answer the following (Any Two) 14
1) Write in details note on HMM and HMM in bioinformatics analysis.
2) Explain the Genbank, EMBL, MSF biological sequence file format.
3) Explain the goals and scope and application of bioinformatics.

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 SLR-VC-48
Seat
No.
Set P
M.Sc. (Semester - I) (CBCS) Examination Nov/Dec-2018
Bioinformatics
CELL BIOLOGY AND GENETICS
Time: 2½ Hours Max. Marks: 70
Instructions: 1) All questions are compulsory.
2) Draw neat and labeled diagrams wherever necessary.
3) Figures to the right indicate full marks.
Q.1 Rewrite the following sentences by using correct altenative 14
1) _________ is a cell organelle known as suicide bags of the cell?
a) Ribosome b) Lysosome
c) Peroxisome d) Mitochondria
2) ____________ is known as programmed cell death.
a) Apoptosis b) Endocytosis
c) Necrosis d) Metastasis
3) ____________ is responsible for replication of nuclear DNA in eukaryotes.
a) DNA polymerase 𝜃 b) DNA polymerase III
c) DNA polymerase 𝛾 d) DNA polymerase 𝛿
4) In eukaryotic translation process ________ acts as initiator tRNA molecule.
a) tRNAmet b) tRNAfmet
c) tRNAval d) tRNAleu
5) In mRNA processing 7-methylguanosine cap is added at the ___________
end of the transcript.
a) 3′ and 5’end b) 3′ end
c) 2′end d) 5′ end
6) During eukaryotic DNA replication process ________ binds directly to
autonomously replicating sequences.
a) DNA polymerase 𝜃 b) DNA polymerase III
c) DNA polymerase 𝛾 d) Origin recognition complex
7) Non-coding DNA sequences present in the eukaryotic genes is also known
as ____________.
a) Introns b) Exons
c) Coding region d) Euchromatin
8) ___________ are also known as communicating junctions.
a) Desmosomes b) Hemi-Desmosomes
c) Gap junctions d) Tight Junctions.
9) ______ is act as secondary messenger molecule during signal transduction.
a) Neurotransmitter b) Enzyme
c) cAMP d) Hormones
10) Cdk stands for _____________.
a) Cycline dependent kinases
b) Caspase dependent kinases
c) Cytochrome depenent kinases
d) Cycline degrading kinases

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11) ___________ is responsible for acidification of stomach.
a) Facilitated diffusion b) Passive transport
c) Proton pump d) Simple diffusion
12) ____________ enzyme is responsible for protein folding.
a) Photolyase b) Photo-reductase
c) Photo-resolvase d) Protein disulfide isomerase
13) In operon, _________ responsible for synthesis of inhibitory protein.
a) Promoter b) Enhancer
c) Regulatory gene d) Operator
14) In BER, _________ responsible for initial recognition of the lesion.
a) AP endonucleases b) DNA epinucleaes
c) DNA Glycosylases d) DNA exonucleases
Q.2. A) Answer any four of the following. 08
1) Enlist functions of RER.
2) Define Cyclins.
3) What are exons and introns?
4) Define operon.
5) What is RNA editing?
6) Distinguish between prokaryotic and eukaryotic cell.
B) Answer the following questions (Any Two) 06
1) What are gap junctions?
2) Write note on NPCs.
3) What is facilitated diffusion?
Q.3. A) Answer the following. (Any Two) 08
1) Describe ultra structure and functions of Chloroplast.
2) Describe signal transduction via G-protein coupled receptors.
3) Explain process of translation in prokaryotes.
B) Answer the following:- (Any One) 06
1) Describe different types of mutations with suitable examples.
2) Explain process of mitosis with neat labeled diagrams.
Q.4. A) Answer the following. (Any Two) 10
1) Describe ultra structure of typical plan cell.
2) Describe process of apoptosis.
3) Explain law of independent inheritance with suitable example.
B) Answer the following:- (Any One) 04
1) Describe process of DNA replication in bacteria.
2) Explain regulation of gene expression in lactose operon.
Q.5. Answer the following. (Any Two) 14
a) Describe mechanisms of D-loop model of DNA replication.
b) Explain types of active transport with suitable examples.
c) Explain protein trafficking in mitochondria and endoplasmic reticulum.

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 SLR-VC-49
Seat
No.
Set P
M.Sc. (Semester – I) (CBCS) Examination Nov/Dec-2018
Bioinformatics
INTRODUCTION TO HTML & BIOSTATISTICS
Time: 2½ Hours Max. Marks: 70
Instructions: 1) All questions are compulsory.
2) Figures to the right indicate full marks.
Q.1 Complete the sentences by selecting correct answer fm the given 14
alternatives:-
1) The most frequently occurring value in the data set is called ________.
a) spread b) mode
c) skewness d) median
2) _________ tag inserts a line horizontally on your web page.
a) <hr> b) <line>
c) <line direction=”horizontal”> d) <tr>
3) Tags and test that are not directly displayed on the page are written in
________ section.
a) <html> b) <head>
c) <title> d) <body>
4) ___________ connects web page.
a) Connector b) Line
c) Hyperlink d) Net
5) The first page of a website is called _________.
a) Design page b) Home page
c) First page d) Main page
6) __________ is considered as the father of Biostatistics.
a) Newton b) Denis Ritchie
c) Sir Francis Galton d) Mendel
7) A __________ tag is used to display the image.
a) picture b) image
c) img d) Src
8) ___________ is the correct HTML tag for adding a background color.
a) <body color=”yellow”>
b) <body bgcolor=”yellow”>
c) <background>yellow</background>
d) <body background=”yellow”>
9) Internet Explorer is ____________.
a) An Icon b) A File Manager
c) A Browser d) The Internet
10) Mean of a set of values is based on ___________.
a) all values b) fifty percent values
c) First and last value d) max and min values

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 SLR-VC-49
11) ________ is the standard text editor that comes with the Microsoft windows
operating system.
a) WordPad b) Excel
c) PPT d) Notepad
12) In biostatics, group of individuals taken for study is called as __________.
a) block b) population
c) group d) flock
13) The characteristics or quantity that may vary from one individual to another
is called _____________.
a) static group b) dynamic group
c) dynamism d) variable
14) Variables whose values cannot be expressed numerically are called _____.
a) Qualitative variable b) Quantitative variables
c) Absolute variables d) Continuous variables
Q.2. A) Answer any four of the following 08
1) What is the meaning of Mark-up language?
2) Define web page.
3) Write types of Lists in html.
4) Define Biostatistics.
5) Write different types of data representation.
B) Write notes on (Any Two) 06
1) MATLAB
2) Random variable
3) Formatting tags.
Q.3. A) Answer the following. (Any Two) 08
1) Explain in detail account of History of HTML.
2) Describe all attributes of table in detail.
3) Write note on test for significance.
B) Answer the following:- (Any One) 06
1) Write and explain applications of biostatistics.
2) Design a simple web page of biological database by using html tags.
Q.4. A) Answer the following. (Any Two) 10
1) Explain all body tags in details also write small program on it.
2) Write merits and demerits of Median.
3) Design a frame template by using HTML.
B) Answer the following:- (Any One) 04
1) Explain form elements in detail.
2) Write a note on ANOVA.
Q.5. Answer the following. (Any Two) 14
a) Design simple registration form using all form tags.
b) Find the mode from the following data:-
Marks 0-10 10-20 20-30 30-40 40-50 50-60
No. of students 3 8 15 20 10 4
c) Write a note on Ordered & Non-Ordered lists.

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 SLR-VC-50
Seat
No.
Set P
M.Sc. (Semester - I) (CBCS) Examination Nov/Dec-2018
Bioinformatics
INTRODUCTION TO PROGRAMMING LANGUAGES & PROGRAMMING
THROUGH C & C++
Time: 2½ Hours Max. Marks: 70
Instructions: 1) All questions are compulsory.
2) Figures to the right indicate full marks.
Q.1 Complete the sentences by selecting correct answer fm the given 14
alternatives:-
1) OOPs stand for __________.
a) Oracle Oriented Programming b) Object Oriented programming
c) Operand oriented Programming d) Open Oriented Project
2) The output of the code below is _________
#include<stdio.h>
void main()
{
int x=5;
if (x<1)
printf(“hello”);
if(x == 5)
printf(“hi”);
else
printf(“no”);
}
a) hi b) hello
c) no d) hihello
3) The ________ is the output of this C code.
#include<stdio.h>
void main()
{
int i = 2;
do
{
printf(“Hi”);
} while (i<2)
}
a) Compile time error b) Hi Hi
c) Hi d) Varies
4) _________ is the output of the following code.
#include<stdio.h>
main()
{
const int a = 5;
a++;
printf(“%d”, a);
}
a) 5 b) 6
c) Runtime error d) Compile error

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 SLR-VC-50
5) ________ is a set of instructions to do complete a particular task.
a) Program b) Algorithm
c) Calculation d) Debug
6) _________ is the keyword used to make a class.
a) class b) struct
c) int d) float
7) _________ is valid C expression.
a) int my_num = 100,000; b) int my_num = 10000;
c) int my num = 1000; d) int $my_num = 10000;
8) ________ Operating System is almost coded in C.
a) Linux b) UNIX
c) Microsoft d) Mac OS
9) Every C Statement must end with a ________.
a) Colon (:) b) Comma (,)
c) Slash(/) d) Semicolon(;)
10) C++ is an OOP language developed by __________.
a) Dennis Ritchie b) Larry Ellison
c) Bjarne Stroustrup d) E. Khann
11) ______ is the process of wrapping up data and functions into a single unit
(called class).
a) Encapsulation b) Inheritance
c) Handling d) Polymorphism
12) _______ is a scope resolution symbol.
a) ; b) :
c) ” “ d) ::
13) _______ plays an important role in initializing objects.
a) Pointer b) Constructor
c) Destructor d) Operator
14) C++ uses a unique keyword called this to represent an object that invokes a
________ function.
a) Member b) Virtual
c) Friend d) Private
Q.2. A) Answer any four of the following. 08
1) Define Pointer.
2) What is mean by Polymorphism?
3) Define Identifier.
4) What is different ways to create a program?
5) Write types of loops with example.
B) Write notes on. (Any Two) 06
1) Write a note on Programming Language.
2) Explain in detail decision making statements in C.
3) Explain data types in C++.
Q.3. A) Answer the following. (Any Two) 08
1) Write a note on History of C.
2) Explain in detail Array in C, also explain its types.
3) Write small program on addition of two numbers with output.
B) Answer the following:- (Any One) 06
1) Write a note on Operator in C++.
2) Write a short note on Pointers with example.

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 SLR-VC-50
Q.4. A) Answer the following. (Any Two) 10
1) Explain in detail Overloading?
2) What is Inheritance? Explain the types of Inheritance.
3) Conditional Statements with example in C
B) Answer the following:- (Any One) 04
1) Explain in detail Polymorphism.
2) Briefly explain the structure of C Program.
Q.5. Answer the following. (Any Two) 14
a) Write a note on File Handling in C programming.
b) Write C++ program on String function.
c) Explain Dynamic memory Allocation in C.

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 SLR-VC-52
Seat
No.
Set P
M.Sc. (Semester - II) (CBCS) Examination Nov/Dec-2018
Bioinformatics
ADVANCED BIOINFORMATICS
Time: 2½ Hours Max. Marks: 70
Instructions: 1) Part-1, Question 1 is compulsory
2) Attempt any four questions from Part-II
3) Figures to the right indicate full marks.
4) Answer to the Part-I and Part-II are to be written in same answer Booklet
only.
Section – I
Q.1 A) Rewrite the sentence after choosing the correct answer from the 07
given alternatives:
1) __________ is clustering method for the creation of Phylogenetic
trees created by Naruya Saitou and Nei in 1987.
a) MP b) ML
c) UPGMA d) N-J
2) The ________ based method makes predictions based on significant
matches of the query sequence with sequences of known genes.
a) Ab initio b) Homology
c) HMM d) Neural network
3) _________ is the replacement of a single amino acid in the primary
structure of a protein with another single amino acid, which is
accepted by the processes of natural selection.
a) PAM b) BLOSUM
c) Pairwise d) Multiple
4) ____________ plant database resource for integrative and
comparative plant genome research.
a) Pathogen b) PHI BASE
c) MIPS d) All of these
5) ORF stands for ___________.
a) Open reading frequency b) Open random frame
c) Open reading Frame d) None of these
6) ___________ is a web-based program that combines neural network
with multiple sequence alignment.
a) PSI PRED b) PHD
c) Protparam d) pfam
7) ___________ is a technique used by molecular biologists to produce
a snapshot of the messenger RNA population.
a) OMIM b) SNP
c) SIFT d) SAGE

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 SLR-VC-52
B) Definitions 07
1) Sequence identity
2) Chip
3) Coil
4) Suffix Tree
5) Protparam
6) Rooted Tree
7) Profile
Section – II
Answer any four of the following.
Q2 Explain identification of SNP in disease and SNP database with its 14
applications.
Q3 Explain in detail UPGMA, NJ, Maximum Parsimony phylogenetic method in 14
details.
Q4 Explain the gene prediction in prokaryotic and eukaryotic in details and add a 14
note on plant and animal database.
Q5 Answer any two of the following. 14
a) Write a note on ExPasy server.
b) Explain KEGG database in detail.
c) Write a note on DNA microarray and its applications.
Q6 Write short notes on. (Any two) 14
a) Smith-waterman algorithm
b) OMIM database
c) PSI and Mega Blast

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 SLR-VC-53
Seat
No.
Set P
M.Sc. (Semester - II) (CBCS) Examination Nov/Dec-2018
Bioinformatics
MICROBIOLOGY AND BIOTECHNOLOGY
Time: 2½ Hours Max. Marks: 70
Instructions: 1) Part-1, Question 1 is compulsory.
2) Attempt any four questions from Part-II.
3) Figures to the right indicate full marks.
4) Answer to the Part-I and Part-II are to be written in same answer Booklet
only.
Section – I
Q.1 A) Rewrite the sentence after choosing the correct answer from the 07
given alternatives:
1) The concept of totipotency was proposed by __________.
a) Haberlandt b) Skoog
c) Cocking d) Miller
2) The genome size of mycoplasma is ___________.
a) 1.5 - 2.5mbps b) 1.7 - 2.3mbps
c) 2.0 - 2.2mbps d) 0.5 - 1.3 mbps
3) ___________ Hormone used to induce shoots in plant.
a) Gibberellins b) Cytokines
c) Both a & b d) None
4) Malachite green is used in ____________ structural staining.
a) Cell wall b) Capsule
c) Endospore d) Falgella
5) LacZ gene is present in ___________ plasmid.
a) pUC19 b) pBR322
c) pUC18 d) Both a & c
6) Serum media is used in __________.
a) Plant cell culture b) Animal cell culture
c) Bacterial d) None
7) Molecular taxonomy is based on __________.
a) 28S rRNA b) 16S rRNA
c) 30S rRNA d) None of these
B) Definitions: 07
1) DNA vaccine
2) HindIII
3) Bacteriophage 𝜆
4) Nucleoid
5) ICSB
6) Clustal W
7) Lytic cycle

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 SLR- VC-53
Section – II
Answer any four of the following.
Q2 Explain general characteristics and classification of plant viruses. 14
Q3 Explain the different artificial media used in animal cell culture media. 14
Q4 Explain the technique of Sanger’s method of DNA sequencing 14
Q5 Answer any two of the following. 14
a) Explain the different staining techniques.
b) Molecular genetic analysis of human diseases.
c) Write a note on bacterial Transformation.
Q6 Write short notes any two of the following. 14
a) GMOs advantages and disadvantages.
b) Gene therapy
c) Phylogenetic tree

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 SLR-VC-54
Seat
No.
Set P
M.Sc. (Semester - II) (CBCS) Examination Nov/Dec-2018
Bioinformatics
BASIC BIOCHEMISTRY AND IMMUNOLOGY
Time: 2½ Hours Max. Marks: 70
Instructions: 1) Part-I, Question 1 is compulsory
2) Attempt any four questions from Part-II
3) Figures to the right indicate full marks.
4) Answer to the Part-I and Part-II are to be written in same answer Booklet
only.
Part – I
Q.1 A) Rewrite the sentence after choosing the correct answer from the 07
given alternatives:
1) Standard free energy is denoted by ________.
a) ∆E o b) ∆Go
c) ∆H o d) ∆F o
2) The name protein was suggested by ____________.
a) Kuhne b) Leninger
c) Watson d) Brezelius
3) Enzymes belong to the class of __________ proteins.
a) Fibrous b) Globular
c) Membrane d) None
4) _________ is a storage polysaccharide.
a) Starch b) Cellulose
c) Pectin d) Chitin
5) ________ is an example of agranulocyte.
a) B cell b) Basophil
c) Neutrophil d) Eosinophil
6) The agent which induces the immune response is ________.
a) Allogen b) Autogen
c) Antigen d) Antibody
7) Interleukins are produced by ____________.
a) RBCs b) WBCs
c) Muscle cells d) None of these
B) Definitions 07
1) Enzyme
2) Thermodynamics
3) Cholesterol
4) Vitamin
5) Neutrophil
6) Autoimmunity
7) Monoclonal antibody

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 SLR- VC-54
Part – II
Answer any four of the following
Q.2 Explain the structural classification of proteins. 14
Q.3 Write a detailed note on innate immunity. 14
Q.4 Explain different types of antigen antibody interactions. 14
Q.5 Answer any two of the following 14
a) Write a note on functions of vitamins.
b) Add a note on classifications of nucleic acids.
c) Define enzyme. Write a note on their classification.
Q.6 Write short notes on any two 14
a) Protein folding
b) Cytokines
c) Hybridoma technology

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 SLR-VC-55
Seat
No.
Set P
M.Sc. (Semester - II) (CBCS) Examination Nov/Dec-2018
Bioinformatics
INDUSTRIAL AND ENVIRONMENTAL BIOTECHNOLOGY
Time: 2½ Hours Max. Marks: 70
Instructions: 1) Part-I, Question 1 is compulsory
2) Attempt any four questions from Part-II
3) Figures to the right indicate full marks.
4) Answer to the Part-I and Part-II are to be written in same answer Booklet
only.
Part – I
Q.1 A) Rewrite the sentence after choosing the correct answer from the 07
given alternatives:
1) Out of following ________ is found to be most carcinogenic.
a) PAH b) Heavy metals
c) Textile dyes d) Air Pollutants
2) Phenyl acetic acid acts as a precursor for the production of ________.
a) Penicillin V b) Penicillin G
c) Penicillin M d) Cyclosporine
3) In Bioreactors ___________ are used to prevent vortex formation.
a) Spargers b) Impellers
c) Baffles d) Both B & C
4) Amylase is a starch hydrolyzing enzyme can be obtained by using
___________.
a) A. Oryzae b) S. Cerevisiae
c) B. Licheniformis d) Both A & C
5) Which of the following techniques are used to maintenances of cultures
a) Slant Culture b) Glycerol Storage technique
c) Iyophilized form technique d) All of these
6) Computers are used in Bioreactor for
a) Data acquisition b) Data analysis
c) A+B d) Either A or B
7) Which of the following are Antifoaming Agent?
a) Alcohol b) Esters
c) Silicones d) All of these
B) Definitions 07
1) Microbial Nutrition
2) Microbial Enzyme
3) SCP
4) Bio indicator
5) Bioremediation
6) Environmental Policy
7) Environmental impact assessment

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Part – II
Answer any four of the following
Q2 Describe about the microbial cell cultivation system. 14
Q3 Discuss in brief on Kinetics of Microbial growth. 14
Q4 Write in details of solid waste management. 14
Q5 Answer any two of the following 14
a) Biotechnology for clean environmental
b) Heavy metal resistance in microbes
c) Streptomycin production
Q6 Answer any two of the following 14
a) Air and media sterilization
b) Measurement and control of bioprocess parameters
c) Degradation of dyes

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 SLR-VC-56
Seat
No.
Set P
M.Sc. (Semester - III) (CBCS) Examination Nov/Dec-2018
Bioinformatics
BIOLOGICAL DATABASE MANAGEMENT SYSTEM
Time: 2½ Hours Max. Marks: 70
Instructions: 1) All questions are compulsory
2) Figures to the right indicate full marks.
Q.1 Complete the sentences by selecting correct answer fm the given 14
alternatives:-
1) In the relational modes, cardinally is termed as ________.
a) Number of tuples b) Number of attributes
c) Number of tables d) Number of constraints
2) Cartesian product in relational algebra is _____________.
a) A Unary operator b) A Binary operator
c) A Ternary operator d) Not defined
3) DML is provided for ___________.
a) Description of logical structure of database
b) Addition of new structures in the database system
c) Manipulation & processing of database
d) Definition of physical structure of database system
4) In a relational model, relations are termed as _________.
a) Tuples b) Attributes
c) Tables d) Rows
5) An entity set that does not have sufficient attributes to form a primary key
is a _________.
a) Strong entity set b) Weak entity set
c) Simple entity set d) Primary entity set
6) In a Hierarchical model records are organized as ___________.
a) Graph b) List
c) Links d) Tree
7) Related fields in a database are grouped to form a __________.
a) Data file b) Data record
c) Menu d) Bank
8) In an E-R diagram an entity set is represent by a _________.
a) Rectangle b) Ellipse
c) Diamond box d) Circle
9) A table joined with itself is called ___________.
a) Join b) Self join
c) Outer join d) Equi join
10) Which of the following is used to declare a record?
a) %ROWTYPE b) %TYPE
c) %CHAR d) %DATE

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 SLR-VC-56
11) __________ is a particular property, which describes the entity.
a) Table b) Relation
c) CHAR d) Attribute
12) A _______ with respect to DBMS relates to user commands that are used
to interact with a data base.
a) Command b) Query
c) Function d) Database
13) You communicate with a RDBMS using _____________.
a) Java b) Perl
c) C d) SQL
14) While working at IBM, __________ created the relational database model.
a) Dennis Ritchie b) Larry Ellison
c) E.F. Codd d) E. Kanh
Q.2. A) Answer of the following (Any Four) 08
1) What is mean by Sub query?
2) Name and describe three types of binary relationships.
3) Define Aggregation.
4) Write components of DBMS.
5) What is Relationship?
B) Write notes on (Any Two) 06
1) Write a note on Relational Algebra.
2) Explain in detail Functional Dependency.
3) Write a short note on RDBMS KERNEL.
Q.3. A) Answer the following (Any Two) 08
1) Write a note on ‘Database Trigger’.
2) Describe in detail SQL and its Statements.
3) Explain in detail data types in PLSQL.
B) Answer the following (Any One) 06
1) Create table using DCL commands.
2) Write a note on three schema architecture in DBMS.
Q.4. A) Answer the following (Any Two) 10
1) What are partial, alternate, artificial, compound and natural key?
2) Write a simple program on DDL statements.
3) Describe Data mining tools in detail.
B) Answer the following (Any One) 04
1) Write a short note on OLAP.
2) Explain in detail domain constraints.
Q.5. Answer the following (Any Two) 14
a) Give brief account on features of DBMS.
b) Write a note on Data Normalization.
c) Explain in detail account on Data Model.

Page 2 of 2
 SLR-VC-57
Seat
No.
Set P
M.Sc. (Semester - III) (CBCS) Examination Nov/Dec-2018
Bioinformatics
ADVANCED BIOPHYSICAL TECHNIQUES
Time: 2½ Hours Max. Marks: 70
Instructions: 1) All questions are compulsory.
2) Figures to the right indicate full marks.
Q.1 Multiple choice Questions:- 14
1) _____________ of the intermolecular bonding interactions below are
possible for a secondary amide.
a) Hydrogen bonding only
b) Vander Waals Interactions Only
c) Ionic Bonding Only
d) Both hydrogen Bonding and ionic Bonding
2) ________ of the following statements is true regarding a secondary amide.
a) It can only participate in hydrogen bonding as a hydrogen bond donor
b) It can only participate in hydrogen bonding as a hydrogen bond acceptor
c) It can participate in hydrogen bonding both as a hydrogen bond donor
and a hydrogen bond acceptor
d) It cannot participate in hydrogen bonding at all
3) __________ of the following major aims in drug design is not related to the
pharmacodynamics of a drug.
a) The reduction of side effects
b) The maximization of activity
c) The reduction of toxicity
d) The maximization of oral bioavailability
4) ________ of the following is a noble gas configuration.
a) 1s2 2s2 b) 1s2 2s22p6
2 2 6 2
c) 1s 2s 2p 3s d) 1s2 2s22p63s23p63d10
5) There are __________ types of molecular orbitals.
a) 1 b) 2
c) 3 d) 4
6) ____________ of the following is non-polar bond.
a) C-H b) C=O
c) N-H d) C-C
7) _____________ of the following bonds is most strongly polarized.
a) C-H b) C=O
c) N-H d) C-N
8) _________ of the following molecules will not display an infrared spectrum.
a) CO2 b) N2
c) Benzene d) HCCH
9) __________ One of the following nuclei has a magnetic moment (so that an
NMR experiment can be performed).
a) 12C b) 16O
14
c) N d) 32S

Page 1 of 3
 SLR-VC-57
10) In a proton NMR experiment with a frequency (𝑣) of 60 MHz, the magnetic
field B require for resonance is 1.4 T. calculate the magnetic field required
for resonance of the proton in a spectrometer with a frequency of 500 MHz.
a) 2.8 T b) 11.7 T
c) 0.7 T d) 14.0 T
11) In a time-of-flight mass spectrometer, the velocity 𝑣 of an accelerated ion is
related to its mass by __________ of the following.
a) Proportion to m (its Mass)
b) Inversely proportional to its mass
c) Proportional to the square root of its mass
d) Inversely proportional to the square root of its mass
12) For the molecule CBr4, the number of peaks which comprise the cluster for
the molecular ion will be __________ of the following.
a) 1 b) 4
c) 5 d) 3
13) A device which converts electrical energy in the form of a current into
optical energy is called as _________.
a) Optical source b) Optical coupler
c) Optical isolator d) Circulator
14) Identify __________ of the following pairs of molecules exhibits both a pure
rotational spectrum and a rotational Raman spectrum.
a) O2 and H2O b) CO2 and N2O
c) CO and CH4 d) NO and DCCH
Q.2. A) Answer any four of the following. 08
1) Valency
2) Hydrogen bond
3) Spectroscopy
4) Circular Dichroism
5) Cuvette
B) Write notes on. (Any Two) 06
1) X-radiation
2) Atomic Force microscopy
3) Electron density
Q.3. A) Answer the following. (Any Two) 08
1) Non-bonding interactions
2) Instrumentation of UV-Visible spectrophotometer
3) Difference between of CD and ORD.
B) Answer the following:- (Any One) 06
1) Write the principle of MALDI TOF.
2) Brief out Electromagnetic spectrum.
Q.4. A) Answer the following. (Any Two) 10
1) Explain the X-Ray Diffraction.
2) Explain principle of Scanning Electron Microscopy.
3) Add a note on Fluorescent microscopy.

Page 2 of 3
 SLR-VC-57
B) Answer the following:- (Any One) 04
1) Define covalent bond. Add a note on its types.
2) Write the working of FTIR.
Q.5. Answer the following (Any Two) 14
a) Briefly explain the principles and theory and instrumentation of NMR
b) Discuss the types of lasers with examples.
c) Application of X-rays in medicine

Page 3 of 3
 SLR-VC-58
Seat
No.
Set P
M.Sc. (Semester - III) (CBCS) Examination Nov/Dec-2018
Bioinformatics
COMPUTATIONAL STRUCTURE BIOLOGY AND DRUG DESIGNING
Time: 2½ Hours Max. Marks: 70
Instructions: 1) All questions are compulsory
2) Figures to the right indicate full marks.
Q.1 Multiple choice Questions:- 14
1) __________ is web based service for analysis, visualization and validation
of NMR structure.
a) Vivaldi b) Olderado
c) Nmrcore d) Nmrclust
2) Metabolism of an oral drug via the liver is called _________.
a) First pass metabolism b) Second pass metabolism
c) Last pass metabolism d) Drug pass metabolism
3) The secondary structure is stabilized by hydrogen bonds between residue I
& ____________.
a) i+5 b) i+7
c) i+4 d) i+2
4) Polar surface area of drug should be ___________.
a) <120 Ao b) <140 Ao
o
c) <150 A d) <200 Ao
5) ______ is database of protein models generated by homology programme.
a) PDB b) CSA
c) Modbase d) 3D crunch
6) Drugs are approved by __________.
a) FAD b) FDD
c) FDA d) FAAD
7) __________ is a method of protein modeling which is used to model those
proteins that do not have homologous proteins with known structure.
a) Helix prediction b) Protein prediction
c) Protein threading d) Secondary structure
8) _________ is the major drug metabolizing enzymes.
a) CYP2C19 b) CYP2A
c) CYP2D6 d) CYP450
9) The __________ loop refers to a single stranded region connecting two
adjacent base paired segments to form bubbles.
a) Buldge b) Interior
c) Multibranch d) Hairpin
10) Pharmacologically inactive compounds are called __________.
a) Prodrug b) Predrug
c) Postdrug d) Biodrug

Page 1 of 2
 SLR-VC-58
11) SSAP automatic structural alignment programme classifies the protein in
_________ database.
a) SCOP b) CATH
c) PDBsum d) PDBeFold
12) A single transmembrane 𝛼-helix is called __________.
a) Peripheral membrane protein
b) Polytopic transmembrane 𝛼-helical
c) Bitopic membrane protein
d) Polytopic transmembrane 𝛽-sheet protein
13) A pattern of DNA sequence that is similar for gene of similar function is
called __________.
a) Motif b) Domain
c) Tunnels d) Pores
14) _______ motif is the most commonly used secondary structure for specific
DNA recognition.
a) Beta-Helix-Beta b) Helix-Beta-Helix
c) Zinc Finger d) Ca Finger
Q.2. A) Answer any four of the following. 08
1) What is STRING DATABASE?
2) What is role of wwPDB database in protein data bank database?
3) What is nuclplot in pdbsumdatabase?
4) What is GRID?
5) What is interior loop in RNA structure prediction?
B) Write notes on. (Any Two) 06
1) Explain the biological pathway database in details.
2) Describe the consequences of drug target mutation.
3) Explain the development of lead library from lead compounds.
Q.3. A) Answer the following. (Any Two) 08
1) Explain PDBe Fold database in detail.
2) Explain the Lipnski rule of five in detail.
3) Explain the architecture of protein structure visualization in various
softwares.
B) Answer the following:- (Any One) 06
1) Explain the combinatorial chemistry in detail.
2) Explain the threading method for prediction protein three dimensional
structures.
Q.4. A) Answer the following. (Any Two) 10
1) Write in details about the Protein-DNA interaction with its tools.
2) Write in detail about pharmacodynamics.
3) Explain protein structure classification database in details.
B) Answer the following:- (Any One) 04
1) Explain the structure based drug designing in detail.
2) Explain the Chou-fasman secondary structure prediction method.
Q.5. Answer the following. (Any Two) 14
a) Write in details about the protein folding and challenges in bioinformatics.
b) Explain the different methods of drug target identification.
c) Explain the RCSB PDB database and protein data bank file format in details.

Page 2 of 2
 SLR-VC-60
Seat
No.
Set P
M.Sc. (Semester - IV) (New) (CBCS) Examination Nov/Dec-2018
Bioinformatics
BIOLOGIAL SIMULATIONS AND MODELING
Time: 2½ Hours Max. Marks: 70
Instructions: 1) Part-1, Question 1 is compulsory
2) Attempt any four questions from Part-II
3) Figures to the right indicate full marks.
4) Answer to the Part-I and Part-II are to be written in same answer Booklet
only.
Section – I
Q.1 A) Rewrite the sentence after choosing the correct answer from the 07
given alternatives:
1) Python was developed by ____________.
a) Stave Jobs b) Dennis Ritchi
c) Guido van Rossum d) None
2) __________ is a named piece of memory that can store a value.
a) Constant b) Array
c) Static d) Variable
3) IDLE stands for __________.
a) Integrated Development Environment
b) Invented Development Environment
c) Independent Development Environment
d) None of these
4) _________ is a sequence of text characters in a program.
a) Code b) String
c) Program d) Data types
5) Simulation is mimicking of ___________.
a) Virtual event b) Real event
c) Both a & b d) None
6) Simulation finds its application in ___________.
a) Physics b) Chemistry
c) Biology d) All
7) Energy is a parameter of ___________.
a) MD b) MC
c) Both a & b d) None
B) Definitions: 07
1) Class
2) Generators
3) Methods
4) Dictionary
5) Simulation
6) Bacterial model
7) Force Field

Page 1 of 2
 SLR- VC-60
Section – II
Q.2 Write a note on principles and applications of simulations. 14
Q.3 Write features of python? Explain features in detail. 14
Q.4 Write a note on molecular mechanics with reference to bio-molecules. 14
Q.5 Answer any two of the following. 14
a) What is list? Explain with example.
b) Explain python Tuples with syntax and example.
c) Add a note on biological models of simulations.
Q.6 Write short notes on. (Any two) 14
a) Characteristics of Python.
b) Energy minimization in simulations.
c) Examples of molecular dynamics

Page 2 of 2
 SLR-VC-61
Seat
No.
Set P
M.Sc. (Semester - IV) (New) (CBCS) Examination Nov/Dec-2018
Bioinformatics
CLINICAL BIOINFORMATICS
Time: 2½ Hours Max. Marks: 70
Instructions: 1) Part-1, Question 1 is compulsory.
2) Attempt any four questions from Part-II.
3) Figures to the right indicate full marks.
4) Answer to the Part-I and Part-II are to be written in same answer Booklet
only.
Part – I
Q.1 A) Rewrite the sentence after choosing the correct answer from the 07
given alternatives:
1) AB SOLID 3 System generates over ___________ gigabases per
turn.
a) 30 b) 20
c) 15 d) 50
2) _____________ locates the pair of genes on the chromosomes.
a) Map Viewer b) Linkage
c) Genetic Mapping d) All of these
3) ________ disease is progressive loss of function of neurons including
death of neuron.
a) Alzeimer’s b) Huntigton’s
c) Parkinsons d) All of these
4) A wide variety of microarray analysis tool written in ___________.
a) C b) C++
c) Python d) R
5) __________ jointly sponsored by American College of Surgeons &
American Society.
a) NCDB b) MHDC
c) NHRD d) PHIBASE
6) __________ is the intermediates and products of metabolism.
a) Metabolites b) Genomics
c) Proteomics d) None
7) _____________ to determine the amount to paid to provider.
a) Provider b) Payer
c) Patient d) Hospital
B) Definitions. 07
1) Linkage
2) COPD
3) Clinical Data Management
4) Adverse Drug Reaction
5) ChIP
6) Transcriptomics
7) System Dynamics

Page 1 of 2
 SLR- VC-61
Part – II
Answer any four of the following
Q.2 Explain Host Pathogen interaction in detail and add a note on host pathogen 14
interaction database.
Q.3 Give a brief account on pharmacogenomics and their application in details. 14
Q.4 Write in detail Next Generation Sequencing QC tools and add a note on basic 14
NGS Chemistry.
Q.5 Answer any two of the following. 14
a) Explain pathology informatics in details.
b) Explain De Novo genome sequencing
c) Explain goals and future challenges in Human Genome Project.
Q.6 Write short notes any two of the following. 14
a) International Classification disease
b) NGS Platforms
c) Ensembl Database

Page 2 of 2
 SLR-VC-62
Seat
No.
Set P
M.Sc. (Semester - IV) (New) (CBCS) Examination Nov/Dec-2018
Bioinformatics
RESEARCH METHODOLOGY AND IPR IN BIOINFORMATICS
Time: 2½ Hours Max. Marks: 70
Instructions: 1) Part-1, Question 1 is compulsory
2) Attempt any four questions from Part-II
3) Figures to the right indicate full marks.
4) Answer to the Part-I and Part-II are to be written in same answer Booklet
only.
Section – I
Q.1 A) Rewrite the sentence after choosing the correct answer from the 07
given alternatives:
1) __________ of the following is a major method of data collection.
a) Questionnaires b) Secondary data
c) Interviews d) All of these
2) It is in this section that you fully interpret & evaluate your results
_________.
a) Introduction b) Method
c) Results d) Discussion
3) A literature review requires ________.
a) Planning b) Clear writing
c) Good writing d) All of these
4) When citation includes more than ___________ authors, only the
surname of the author is cited followed by et al.
a) 2 b) 4
c) 5 d) 6
5) The term ‘Intellectual Property Rights’ covers __________.
a) Copyright b) Patent
c) Trade dress d) All of the above
6) World Intellectual Property Organization was established in _______.
a) 14 March, 1959 b) 14 July, 1967
c) 14 August, 1965 d) 14 October, 1960
7) ___________ is a preferred sampling method for the population with
finite size.
a) Area sampling b) Cluster sampling
c) Purposive sampling d) Systematic sampling
B) Definitions. 07
1) Scientific journal
2) Research report
3) ANOVA
4) Hypothesis
5) Trade secrets
6) Impact factor
7) Fundamental research

Page 1 of 2
 SLR-VC-62
Section – II
Answer any four of the following.
Q2 Explain in detail the title and abstract guidelines for preparation manuscript. 14
Q3 What is Sampling? Explain in detail Types of Sampling. 14
Q4 What is research methodology? Explain in detail steps in research. 14
Q5 Answer any two of the following. 14
a) Write a note patenting of biological materials.
b) Write a note computer and internet application in research.
c) Write a note on Review of Literature.
Q6 Answer any two of the following. 14
a) Intellectual property
b) Sampling and non sampling error
c) Plant variety protection in India

Page 2 of 2
 SLR-VC-63
Seat
No.
Set P
M.Sc. (Semester - IV) (New) (CBCS) Examination Nov/Dec-2018
Bioinformatics
EMERGING AREAS OF BIOINFORMATICS
Time: 2½ Hours Max. Marks: 70
Instructions: 1) Part-1, Question 1 is compulsory
2) Attempt any four questions from Part-II
3) Figures to the right indicate full marks.
4) Answer to the Part-I and Part-II are to be written in same answer Booklet
only.
Part – I
Q.1 A) Rewrite the sentence after choosing the correct answer from the 07
given alternatives:
1) __________ is a multilateral treaty to protect endangered plants and
animals.
a) SITES b) ISBN
c) ICZN d) CITES
2) The most formats was created by __________ Information Systems.
a) MDL b) SDF
c) US d) Canada
3) __________ medicine is a medical procedure that separates patients
into different groups.
a) genetic b) Natural
c) Preservative d) Personalized
4) MHCpred 2.0 an updated quantitative ________ epitope prediction
server.
a) B-Cell b) Cyctotoxic
c) T-Cell d) All
5) The ______ is a complex system of the human body and understanding
it is one of the most challenging topics in biology.
a) Blood b) immune
c) Respiratory d) Reproductive
6) _________ coined the term the nanotechnology.
a) Richard Fymann b) Nario Taniguchi
c) Gopal Chandra d) Robert Koch
7) ________ is a database of chemicals which is owned by the Royal
Society of Chemistry.
a) ChemSpider b) Pubchem
c) Zinc d) ChEBI

Page 1 of 2
 SLR- VC-63
B) Definitions 07
1) QSPR
2) 2D compounds
3) Polyphen
4) Nano
5) Disease
6) CML
7) TDWG
Part – II
Answer any four of the following
Q2 Explain different chemical file format and add a note on chemical database. 14
Q3 Give a detailed account on Biodiversity informatics and explain the molecular 14
data types in phylogenic study.
Q4 Explain in brief about the immunoinformatics and add a note on reverse 14
vaccinology.
Q5 Answer any two of the following 14
a) Write a note on personalized medicine in details.
b) Describe physical method for synthesis of nanomaterials.
c) Write a note on MHC prediction in detail.
Q6 Answer any two of the following 14
a) FTIR and its application
b) SNP database
c) Species 2000

Page 2 of 2
 SLR-VC-65
Seat
No.
Set P
M.Sc. (Semester - IV) (Old) (CBCS) Examination Nov/Dec-2018
Bioinformatics
BIOLOGIAL SIMULATIONS AND MODELING
Time: 2½ Hours Max. Marks: 70
Instructions: 1) Part-1, Question 1 is compulsory
2) Attempt any four questions from Part-II
3) Figures to the right indicate full marks.
4) Answer to the Part-I and Part-II are to be written in same answer Booklet
only.
Section – I
Q.1 A) Rewrite the sentence after choosing the correct answer from the 07
given alternatives:
1) Python was developed by ____________.
a) Stave Jobs b) Dennis Ritchi
c) Guido van Rossum d) None
2) __________ is a named piece of memory that can store a value.
a) Constant b) Array
c) Static d) Variable
3) IDLE stands for __________.
a) Integrated Development Environment
b) Invented Development Environment
c) Independent Development Environment
d) None of these
4) _________ is a sequence of text characters in a program.
a) Code b) String
c) Program d) Data types
5) Simulation is mimicking of ___________.
a) Virtual event b) Real event
c) Both a & b d) None
6) Simulation finds its application in ___________.
a) Physics b) Chemistry
c) Biology d) All
7) Energy is a parameter of ___________.
a) MD b) MC
c) Both a & b d) None
B) Definitions: 07
1) Class
2) Generators
3) Methods
4) Dictionary
5) Simulation
6) Bacterial model
7) Force Field

Page 1 of 2
 SLR- VC-65
Section – II
Q.2 Write a note on principles and applications of simulations. 14
Q.3 Write features of python? Explain features in detail. 14
Q.4 Write a note on molecular mechanics with reference to bio-molecules. 14
Q.5 Answer any two of the following. 14
a) What is list? Explain with example.
b) Explain python Tuples with syntax and example.
c) Add a note on biological models of simulations.
Q.6 Write short notes on. (Any two) 14
a) Characteristics of Python.
b) Energy minimization in simulations.
c) Examples of molecular dynamics

Page 2 of 2
 SLR-VC-66
Seat
No.
Set P
M.Sc. (Semester - IV) (Old) (CBCS) Examination Nov/Dec-2018
Bioinformatics
CLINICAL BIOINFORMATICS
Time: 2½ Hours Max. Marks: 70
Instructions: 1) Part-1, Question 1 is compulsory.
2) Attempt any four questions from Part-II.
3) Figures to the right indicate full marks.
4) Answer to the Part-I and Part-II are to be written in same answer Booklet
only.
Part – I
Q.1 A) Rewrite the sentence after choosing the correct answer from the 07
given alternatives:
1) AB SOLID 3 System generates over ___________ gigabases per
turn.
a) 30 b) 20
c) 15 d) 50
2) _____________ locates the pair of genes on the chromosomes.
a) Map Viewer b) Linkage
c) Genetic Mapping d) All of these
3) ________ disease is progressive loss of function of neurons including
death of neuron.
a) Alzeimer’s b) Huntigton’s
c) Parkinsons d) All of these
4) A wide variety of microarray analysis tool written in ___________.
a) C b) C++
c) Python d) R
5) __________ jointly sponsored by American College of Surgeons &
American Society.
a) NCDB b) MHDC
c) NHRD d) PHIBASE
6) __________ is the intermediates and products of metabolism.
a) Metabolites b) Genomics
c) Proteomics d) None
7) _____________ to determine the amount to paid to provider.
a) Provider b) Payer
c) Patient d) Hospital
B) Definitions. 07
1) Linkage
2) COPD
3) Clinical Data Management
4) Adverse Drug Reaction
5) ChIP
6) Transcriptomics
7) System Dynamics

Page 1 of 2
 SLR- VC-66
Part – II
Answer any four of the following
Q.2 Explain Host Pathogen interaction in detail and add a note on host pathogen 14
interaction database.
Q.3 Give a brief account on pharmacogenomics and their application in details. 14
Q.4 Write in detail Next Generation Sequencing QC tools and add a note on basic 14
NGS Chemistry.
Q.5 Answer any two of the following. 14
a) Explain pathology informatics in details.
b) Explain De Novo genome sequencing
c) Explain goals and future challenges in Human Genome Project.
Q.6 Write short notes any two of the following. 14
a) International Classification disease
b) NGS Platforms
c) Ensembl Database

Page 2 of 2
 SLR-VC-68
Seat
No.
Set P
M.Sc. (Semester - IV) (Old) (CBCS) Examination Nov/Dec-2018
Bioinformatics
EMERGING AREAS OF BIOINFORMATICS
Time: 2½ Hours Max. Marks: 70
Instructions: 1) Part-1, Question 1 is compulsory
2) Attempt any four questions from Part-II
3) Figures to the right indicate full marks.
4) Answer to the Part-I and Part-II are to be written in same answer Booklet
only.
Part – I
Q.1 A) Rewrite the sentence after choosing the correct answer from the 07
given alternatives:
1) __________ is a multilateral treaty to protect endangered plants and
animals.
a) SITES b) ISBN
c) ICZN d) CITES
2) The most formats was created by __________ Information Systems.
a) MDL b) SDF
c) US d) Canada
3) __________ medicine is a medical procedure that separates patients
into different groups.
a) genetic b) Natural
c) Preservative d) Personalized
4) MHCpred 2.0 an updated quantitative ________ epitope prediction
server.
a) B-Cell b) Cyctotoxic
c) T-Cell d) All
5) The ______ is a complex system of the human body and understanding
it is one of the most challenging topics in biology.
a) Blood b) immune
c) Respiratory d) Reproductive
6) _________ coined the term the nanotechnology.
a) Richard Fymann b) Nario Taniguchi
c) Gopal Chandra d) Robert Koch
7) ________ is a database of chemicals which is owned by the Royal
Society of Chemistry.
a) ChemSpider b) Pubchem
c) Zinc d) ChEBI

Page 1 of 2
 SLR- VC-68
B) Definitions 07
1) QSPR
2) 2D compounds
3) Polyphen
4) Nano
5) Disease
6) CML
7) TDWG
Part – II
Answer any four of the following
Q2 Explain different chemical file format and add a note on chemical database. 14
Q3 Give a detailed account on Biodiversity informatics and explain the molecular 14
data types in phylogenic study.
Q4 Explain in brief about the immunoinformatics and add a note on reverse 14
vaccinology.
Q5 Answer any two of the following 14
a) Write a note on personalized medicine in details.
b) Describe physical method for synthesis of nanomaterials.
c) Write a note on MHC prediction in detail.
Q6 Answer any two of the following 14
a) FTIR and its application
b) SNP database
c) Species 2000

Page 2 of 2