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    Antitussives and Expectorants

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    wawa chen
    This document provides information on several common antitussive and expectorant medications including dosage, indications, side effects and precautions. It discusses acetylcysteine, bromhexine, ambroxol, brown mixture, hydropropizine, eprazinone, benzonatate, guaifenesin, codicon-U, dextromethorphan, codin-P syrup, secornie syrup and their various brand names, uses, and administration guidelines for both children and adults. Potential adverse reactions and situations where the drugs should be used cautiously are also outlined.

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    Antitussives and Expectorants

    Uploaded by

    wawa chen
    66 views7 pages
    This document provides information on several common antitussive and expectorant medications including dosage, indications, side effects and precautions. It discusses acetylcysteine, bromhexine, ambroxol, brown mixture, hydropropizine, eprazinone, benzonatate, guaifenesin, codicon-U, dextromethorphan, codin-P syrup, secornie syrup and their various brand names, uses, and administration guidelines for both children and adults. Potential adverse reactions and situations where the drugs should be used cautiously are also outlined.

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    This document provides information on several common antitussive and expectorant medications including dosage, indications, side effects and precautions. It discusses acetylcysteine, bromhexine, ambroxol, brown mixture, hydropropizine, eprazinone, benzonatate, guaifenesin, codicon-U, dextromethorphan, codin-P syrup, secornie syrup and their various brand names, uses, and administration guidelines for both children and adults. Potential adverse reactions and situations where the drugs should be used cautiously are also outlined.

    Copyright:

    © All Rights Reserved
    Download as DOC, PDF, TXT or read online from Scribd
    Download as doc, pdf, or txt
    66 views7 pages

    Antitussives and Expectorants

    Uploaded by

    wawa chen
    This document provides information on several common antitussive and expectorant medications including dosage, indications, side effects and precautions. It discusses acetylcysteine, bromhexine, ambroxol, brown mixture, hydropropizine, eprazinone, benzonatate, guaifenesin, codicon-U, dextromethorphan, codin-P syrup, secornie syrup and their various brand names, uses, and administration guidelines for both children and adults. Potential adverse reactions and situations where the drugs should be used cautiously are also outlined.

    Copyright:

    © All Rights Reserved
    Download as DOC, PDF, TXT or read online from Scribd
    Download as doc, pdf, or txt
    of 7

    Antitussives and Expectorants

    Acetylcysteine B
    Brand name：
    Fluimucil granule; Encore
    200mg/3gm/pack
    ACC 600 Effervescent tab
    600mg/發泡錠
    醫令碼:OFLUMA
    醫令碼:OACC6
    Indication：
    Adjunctive mucolytic therapy; antidote for acute
    acetaminophen toxicity.
    Dosage：
    Granule-
    Adults: 200mg tid.
    Children: 100 or 200mg bid~qid.
    Acetaminophen poisoning-
    Children and Adults: Oral 140 mg/kg, then
    17 dose of 70mg/kg every 4 hrs.
    Syrup-(1ml = 20mg)
    Childn 2 yrs: 2.5 ml, 2-6 yrs: 5 ml, > 6 yrs: 10
    cc, tid.
    Effervescent (勿磨粉)
    一天1~2 次(晚上服用佳)
    Side effect：
    Vomiting, unpleasant odor during administration,
    drowsiness, nausea, irritation, bronchospasm.
    Precaution：
    If bronchospasm progress, discontinue acetyl
    cysteine.
    Bromhexine HCl
    Brand name：
    Wincou(bisolvon) 8mg/tab 醫令碼：OBISO
    Indication：
    Bronchial mucolytic, expectorant.
    Dosage：
    Adults: 8-16mg 3 times daily.
    Childn <3-6 years: 1/4 tab tid.
    Childn 6-12 years: 4mg qid.
    Contraindication：
    Gastric ulcer.
    Side effect：
    Nausea, vomiting, headache, rash, liver
    dysfunction.
    Precaution：
    Can dissociate gastric mucosal barrier.
    Ambroxol HCl
    Brand name：
    Ambroxol 30mg/tab 醫令碼：OAMBR
    Indication：
    Expectorant.
    Dosage：
    Adults and children > 12 yrs: 30mg tid.
    Childn 6-12 yrs: 15mg tid.
    Side effect：
    Dyspepsia, nausea, vomiting, heartburn.
    Precaution：
    1. Ambroxol is bromhexine of active metabolite.
    2. Be careful to use in pregnant (the 􀀁rimesters
    gestation).
    3. 本品含阿斯巴甜，苯酮尿症患者不宜使用.
    Brown mixture
    200 mL/bot,
    120 mL/bot
    Each ml Contains:
    Glycyrrhiza fluid extract
    0.12 ml
    Opium Tincturer 0.012 ml
    Antimony Potassium tartrate
    0.24 mg
    Ethinyl Nitrite Spirit 0.03 ml
    (OBML)
    醫令碼：OBML
    醫令碼：OBM
    Indication：
    咳嗽、袪痰
    Dosage：
    5 ml tid- qid.
    Contraindication：
    Severe respiratory depression, serious liver
    dysfunction, acute alcoholism, constipation.
    Side effect：
    Respiratory depression, restless, dizziness,
    diaphoresis, exciting.
    Precaution：
    1. Produce addictive.
    2. Avoid using in pregnant.
    Hydropropizine
    Brand name：
    Sintabex 30mg/tab 醫令碼：OSINT
    Indication：
    Antitussive, expectorant.
    Dosage：
    30mg tid-qid.
    Precaution：
    投與高劑量時，可能引起腎上腺激素樣(如起
    立性高血壓)。
    Eprazinone di-HCl
    Brand name：
    Debronc 50mg/tab 醫令碼：ODEBR
    Indication：
    Antitussive, expectorant (bronchiectasis,
    asthmatic bronchitis, acute/chronic bronchitis,
    flu).
    Dosage：
    Adults: 50-100 mg tid.
    Childn 1-2 yrs: 10-20mg tid.
    3-5 yrs: 20-30mg tid.
    6-9 yrs: 30-45mg tid.
    Side effect：
    GI disturbances, headache.
    Benzonatate
    Brand name：
    Zough
    100mg/cap
    醫令碼：OBENS
    Indication：
    Cough.
    Dosage：
    100mg tid.
    Side effect：
    GI disturbance, nasal congestion, headache.
    Guaifenesin C
    Brand name：
    Robitussin syrup 120ml/bot
    Robitussin syrup 20mg/ml
    醫令碼：OROBSB
    (OPD use)
    醫令碼：OROB99
    (UDD use)
    Indication：
    Expectorant.
    Dosage：
    Adults and childn 12 yrs: 10ml/time q4h.
    Childn 6-12 yrs: 5ml/time q4h.
    Childn 2-6 yrs: 2.5mg/time, q4h.
    Side effect：
    Nausea, GI upset anorexia.
    Codicon-U
    (Medicon-A, Romicon-A)
    C
    Each cap contains：
    Lysozyme HCl 20mg
    Potassium cresolsulfonate
    90mg
    Dextromethorphan HBr
    20mg
    醫令碼：OMEDA
    Indication：
    Antitussive, expectorant.
    Dosage：
    >15 years: 1 cap tid.
    or (15 歲以下仿單未建議使用劑量
    以 Dextromethorphan 成分計算)
    Oral:
    Children-
    <4 years: Not for OTC use
    4-6 years (syrup): Oral: 2.5-7.5 mg every 4-8
    hours; extended release is 15 mg twice daily
    (maximum: 30 mg/24 hours).
    6-12 years: 5-10 mg every 4 hours or 15 mg every
    6-8 hours; extended release is 30 mg twice daily
    (maximum: 60 mg/24 hours).
    Children >12 years: Refer to adult dosing.
    Adult:10-20 mg every 4 hours or 30 mg every 6-8
    hours; extended release: 60 mg twice
    daily;maximum: 120 mg/day.
    Contraindication：
    Concomitant use or use within 14 days of MAOI.
    Side effect：
    Drowsiness, nausea, vomiting.
    Precaution：
    1.Overdose can produce hyperkalemia.
    2.Do not use for persistent or chronic cough.
    Dextromethorphan HBr C
    Brand name：
    Methon 30mg/tab
    Ancou 30mg/tab
    Detosiv SR 60mg/tab
    Basson inj 10mg/ml/amp
    醫令碼：OMEDI
    醫令碼：OMIDA
    醫令碼：ODETO
    醫令碼：IBASS
    Indication：
    To control non-productive cough.
    Dosage：
    Oral:
    Children-
    1-3 months: 0.5-1mg q6-8h
    3-6 months: 1-2mg q6-8h
    7mo ~ 1yrs: 2-4mg q6-8h
    2-6 yrs: 2.5-7.5 mg q4-8h
    7-12 yrs: 5-10mg q4h or 15mg q6-8hr.
    > 12 yrs and adults-
    10-30mg q4-8h
    SR tab: 1 tab Q12h
    Injection: only IM
    Adult: 0.5-1ml qd ~ bid
    Contraindication：
    Concomitant use or use within 14 days of MAOI.
    Side effect：
    Drowsiness, coma, respiratory depression, GI
    upset, abdominal discomfort.
    Precaution：
    1. Use in children <12 years of age has not been
    proven safe and effective.
    2. Injection 限安寧病房使用。
    3. Do not use for persistent or chronic cough, or
    for cough accompanied by excessive secretion.
    Codin-P syrup C
    Per ml contains: (60ml/bot)
    Platycodon fluid extract 0.06ml
    Codeine phosphate 0.48mg
    dl- Methylephedrine HCl 1mg
    Chlorpheniramine 0.2mg
    Potassium guaiacol sulfonate
    3mg
    醫令碼：OCODI
    Indication：
    Antitussive, expectorant.
    Dosage：
    Childn < 2 years: 1ml/time, 2-3 years: 2ml/time,
    4-6 years: 3ml/time, 7-11 years: 4ml/time, 12-14
    year 5ml/time, > 15 years: 10ml/time, tid.
    Contraindication：
    MAOI, Alcohol.
    Side effect：
    Nausea, vomiting, sedation.
    管制藥品：管4
    Secorine syrup
    Each ml contains:
    DL-methylephedrine HCL
    1mg
    Chlorpheniramine Maleate
    0.1mg
    Guaifenesin 5mg (120ml/bot)
    醫令碼：OSECO
    Indication：
    緩解感冒之各種症狀 (流鼻水、鼻塞、打噴嚏、
    咽喉痛、發燒、頭痛、關節痛、肌肉痛)。
    Dosage：
    Adults: 10ml tid-qid.
    Childn: 5ml tid-qid.
    Side effect：
    輕微思睡。

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