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    Discussion Connective Tissue Disorder

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    Jean Dupont

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    Discussion Connective Tissue Disorder

    Uploaded by

    Jean Dupont
    7 views3 pages

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    7 views3 pages

    Discussion Connective Tissue Disorder

    Uploaded by

    Jean Dupont

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    of 3

    Connective Tissue Disorders

    Connective Tissue is a fibrous tissue that supports and connects internal organs, forms

    bone and the walls of blood vessels, attaches muscles and bones to bones (tendons and
    ligaments) and replaces tissue following injury (scar tissue). The long fibers of connective tissue

    contain protein called collagen. Connective tissue disorders are also known as rheumatologic

    disorders. They affect the integrity of the musculoskeletal system and may also affect blood

    vessels, the skin, lungs and a variety of organs. They are chronic and may lead to disability;

    however, they can usually be controlled with medication.

    Assessment for connective tissue disorders focuses on the musculoskeletal system, but

    also involves remote body systems. Clues to connective disorders may found in the skin, eyes,

    lungs, and neurologic system. Functional assessment is also important; many questionnaires and

    scales have been developed to assess patient function or disability related to connective tissue

    disorders.

    Osteoarthritis (Degenerative Joint Disease)

    Osteoarthritis is an extremely common generalized disorder characterized pathologically

    by loss of joint cartilage and reactive new formation. Part of wear and tear of the aging process,

    degenerative joint disease tends to affect predominantly the weight-bearing joints (spine, hip,

    knee and ankle) and the interphalangeal joints of the fingers. A secondary form of degenerative

    joint disease may develop in joint that has been repeatedly traumatized or subjected to abnormal

    stresses because of orthopedic deformities, or it may be result of septic or inflammatory arthritis

    that destroy the cartilage.

    Gout

    Gout is a disorder in the metabolism of purine (a component of nucleic acids) in which an

    increase in the blood level of uric acid leads to the deposition of uric acid crystals in the joints,
    cartilage, and kidney. Several inherited enzyme defects can cause overproduction of uric acid

    (primary gout). In secondary gout, hyperuricemia can be caused by an overproduction of uric

    acid which in turn may be cause an increased turnover of nucleic acids.

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