This document provides definitions for various antibiotic classes and examples of drugs within each class. It explains how different antibiotic classes work, whether by killing bacteria or preventing their ability to multiply. While data on all antibiotic classes are included in the national Antibiotic Resistance Patient Safety Atlas, not all classes have state-level data available in map format.
This document provides definitions for various antibiotic classes and examples of drugs within each class. It explains how different antibiotic classes work, whether by killing bacteria or preventing their ability to multiply. While data on all antibiotic classes are included in the national Antibiotic Resistance Patient Safety Atlas, not all classes have state-level data available in map format.
This document provides definitions for various antibiotic classes and examples of drugs within each class. It explains how different antibiotic classes work, whether by killing bacteria or preventing their ability to multiply. While data on all antibiotic classes are included in the national Antibiotic Resistance Patient Safety Atlas, not all classes have state-level data available in map format.
This document provides definitions for various antibiotic classes and examples of drugs within each class. It explains how different antibiotic classes work, whether by killing bacteria or preventing their ability to multiply. While data on all antibiotic classes are included in the national Antibiotic Resistance Patient Safety Atlas, not all classes have state-level data available in map format.
The Outpatient Antibiotic Prescription data section of the Patient Safety Atlas provides data on oral antibiotic prescriptions dispensed to outpatients in U.S. community pharmacies. Antibiotics are usually classified or grouped by their chemical structure. Some antibiotic classes work by killing bacteria and others work by preventing the ability of bacteria to multiply. All of these antibiotics are currently included in the AR Patient Safety Atlas national data, but not all are available in the map format of state data. Class Examples How They Work Penicillins penicillin, amoxicillin Penicillins kill bacteria by preventing formation of the bacterial cell wall. Macrolides azithromycin, Macrolides prevent bacteria from multiplying by erythromycin keeping bacteria from making proteins. Cephalosporins cephalexin, cefdinir Cephalosporins kill bacteria by preventing formation of the bacterial cell wall. Fluoroquinolones ciprofloxacin, levofloxacin Fluoroquinolones kill bacteria by keeping bacteria from making DNA. Beta-lactams with amoxicillin/clavulanate, Beta-lactams with increased activity are combinations increased activity ceftazidime/avibactam that consist of two different drugs: a penicillin or cephalosporin and a beta-lactamase inhibitor. The penicillin or cephalosporin kills bacteria by preventing formation of the bacterial cell wall. The beta-lactamase inhibitor has little antibiotic activity on its own. Its job is to protect the penicillin or cephalosporin from being destroyed by an enzyme some bacteria produce. This protection increases the activity of the penicillin or cephalosporin. Tetracyclines tetracycline, doxycycline Tetracyclines prevent bacteria from multiplying by keeping bacteria from making proteins. Trimethoprim- trimethoprim- Trimethoprim and sulfamethoxazole work together to sulfamethoxazole sulfamethoxazole inhibit the ability of bacteria to make folic acid, which is necessary to make DNA and proteins. This prevents bacteria from multiplying. Urinary anti- nitrofurantoin Depends of the specific drug. For nitrofurantoin, infectives depending on the concentration, it either kills bacteria or prevents them from multiplying by keeping bacteria from making DNA, proteins, and the bacterial cell wall. Lincosamides clindamycin Lincosamides prevent bacteria from multiplying by keeping bacteria from making proteins.
National Center for Emerging and Zoonotic Infectious Diseases