Standard operation procedure

294 - 1

Service manual LAURA M

Draw up by
ŠVP Ing. Michal SPĚŠNÝ, Ph.D. ......................... ...........................

Date of validity 14.02.2012

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Erba Lachema s.r.o.
Standard operation procedure 294-1 Date of validity: 14.02.2012
Service manual LAURA M

Table of contents
1 EQUIPMENT OVERVIEW................................................................................................................................... 4
1.1 EXTERIOR .................................................................................................................................................................. 4
1.2 EQUIPMENT PARAMETERS ......................................................................................................................................... 5
1.3 FEATURES AND FUNCTIONALITIES ............................................................................................................................. 5
1.4 WORKING ENVIRONMENT .......................................................................................................................................... 6
2 SOFTWARE ............................................................................................................................................................ 6
2.1 EQUIPMENT INITIALIZATION ...................................................................................................................................... 6
2.2 TOP MAIN BOARD SELF-TEST PROGRAM ................................................................................................................... 7
2.2.1 LCD Screen Self-test ........................................................................................................................................ 7
2.2.2 Printer Self-test ................................................................................................................................................ 7
2.3 SOFTWARE UPGRADE ................................................................................................................................................. 7
2.3.1 Upgrade Preparation ...................................................................................................................................... 7
2.3.2 Bottom Main Board Upgrade ........................................................................................................................ 10
2.3.3 Top Board Upgrade ....................................................................................................................................... 14
2.4 SERIAL PORT COMMUNICATION............................................................................................................................... 18
2.4.1 Connection ..................................................................................................................................................... 18
2.4.2 Specifications ................................................................................................................................................. 18
2.4.3 Data Transfer ................................................................................................................................................ 19
3 DISASSEMBLE .................................................................................................................................................... 20
3.1 ANALYSER STRUCTURE ........................................................................................................................................... 20
3.1.1 Exterior .......................................................................................................................................................... 20
3.1.2 Component Layout ......................................................................................................................................... 21
3.1.3 Electrical Diagram ........................................................................................................................................ 21
3.1.4 Power Diagram ............................................................................................................................................. 22
3.1.5 Insulation Diagram........................................................................................................................................ 22
3.2 OVERALL STRUCTURE DIAGRAM ............................................................................................................................. 23
3.3 FEEDING PLATE ....................................................................................................................................................... 24
3.4 WASTE STRIPE BOX ................................................................................................................................................. 26
3.5 OPEN THE TOP SHELL .............................................................................................................................................. 28
3.6 TOP PART COMPONENTS .......................................................................................................................................... 29
3.7 BOTTOM PART COMPONENTS .................................................................................................................................. 30
3.8 SENSORS .................................................................................................................................................................. 31
3.9 FEEDING MECHANISM.............................................................................................................................................. 34
4 ADJUSTMENT ..................................................................................................................................................... 35
4.1 USER THRESHOLD ADJUSTMENTS ............................................................................................................................ 35
5 MAINTENANCE .................................................................................................................................................. 38
5.1 DAILY MAINTENANCE AND CAUTIONS .................................................................................................................... 38
5.1.1 Feeding Plate................................................................................................................................................. 38
5.1.2 Carrier Belt ................................................................................................................................................... 38
5.1.3 Waste Stripe Box ............................................................................................................................................ 39
5.1.4 Waste liquid plate .......................................................................................................................................... 39
5.2 STERILIZATION ........................................................................................................................................................ 39
5.3 PERIODIC CLEANING ................................................................................................................................................ 39
6 ERROR MESSAGES AND SOLUTIONS .......................................................................................................... 40
6.1 ERROR CODE TABLE ................................................................................................................................................ 40
6.2 OTHER MALFUNCTIONS AND SOLUTIONS ................................................................................................................ 42

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Service manual LAURA M
7 SAFETY PRECAUTIONS ................................................................................................................................... 43

8 TABLE OF REVISIONS ...................................................................................................................................... 43

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Standard operation procedure 294-1 Date of validity: 14.02.2012
Service manual LAURA M

1 Equipment Overview
The “Laura M” Urine Analyzer is developed with the newest micro processing technology and
photometry technology to meet the clinical testing needs. It works under AC 100-240 Volts.

1.1 Exterior

Figure 3.1

Figure 3.2

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Standard operation procedure 294-1 Date of validity: 14.02.2012
Service manual LAURA M
1.2 Equipment Parameters
Specification Parameters
Testing Principles The reflective photometer reads the colour changes on the
stripe to calculate the concentration of each testing item and
output a semi quantitative analysis result.
Testing Wave Length 470nm, 525nm, 625nm
Testing Speed 600 samples/ hour
Output LCD display, serial port output
Embedded 57mm thermal printer
External dot matrix printer
LCD Screen 320X240 dot-matrix LCD
Input Touch Screen
Report Storage Stores up to 2000 sets of results
External Ports Connects to PC through a RS-232 serial port;
External 25-pin parallel port for printer
Working Voltage AC100-240V 50/60Hz
Power ≤ 45 VA
Size 390*330*210 mm
Weight 6 kgs

1.3 Features and Functionalities

The Laura M Urine Analyzer is a semi-automated clinical equipment that adopts the newest
micro-processing technology and photometry technology. This user-friendly analyzer gives
accurate testing results.

Laura M features the following designs:

Aesthetically appealing design

Reliable and compact hardware design

32-bit RISC to minimize periphery parts and increase reliability

High performance bipolar stepper motor

Adopts the high brightness white LED that has high system signal to noise ratio and longer
life

RGB sensing principal to avoid interference and increase adaptability

Professional power adapter for safety and adaptability

Data is saved in the flash memory simultaneously as testing proceeds. No data is lost after
shutting down or power out

Friendly user interface, easy to learn, easy to operate

Saves up to 2000 results. Sorts by dates and categories for convenient management

Upgrading the software by connecting the analyzer to a computer through the serial ports

Infrared sensor detects the motion of placing a stripe on the feed plate to automatically start a
test

Sophisticated stripe position check system. Tests in progress are not interrupted by errors

Equipped with waste box to collect used stripes

Waste plate collects extra liquid to minimize the contamination to the machine
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Service manual LAURA M
1.4 Working environment
Please avoid placing the equipment under high temperature and high humidity environment. For
better performance, please keep temperature and humanity stable. The ideal temperature is 10 °C
to 30 °C and the humanity should not exceed 80 %. Please place the equipment on the firm, level
surface. If any of the four feet cannot touch the surface firmly, please adjust the leveler at the
back left (see figure 3.3) to make sure the instrument is firmly placed on the working surface
(twist clockwise to lower the leveler, anti-clockwise to higher the leveler).

Figure 3.3 Adjustable foot

Please avoid operating in the following environment:

In direct sunlight

Near flammable and explosive gas

Next to an opened window

Next to heating or refrigeration equipments

Near strong light source

2 Software

2.1 Equipment Initialization

Connect the equipment to power and turn switch to “ | ”. Operation system starts and displays the
logo. Then the system checks the memory and load user’s settings.
When power is on, a progress bar shows on the screen under the logo and the analyzer starts
a self-test. For error code information, please refer to Chapter 8: Solution to Errors.
Self-test procedures are as follows:
Check Flash ROM and RAM. If error is detected in the Flash ROM checking, or any bit writing
error to RAM, system halts and error code E01, E02, or E03 is displayed.
Scan head move back and search for start position. If the search fails, system halts and error code
E21 is displayed.

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Service manual LAURA M
Stripe feeding system checks mechanical system. If any error is found, error code E10 or E11
is displayed.
Test the brightness of stray light and reflection of white standard chip. If any error is found, error
code E23 or E24is displayed.
After all the tests, display main menu.

2.2 Top Main Board Self-test Program

Before turning on, pull out the waste stripe box, then set the toggle switch in the middle (see
page 10). Turn on the analyzer. Before the progress bar under the logo is full to the right, “E01
System Software Error” will pop up. Press “START” button to start top board self-test program.
Self-test procedures should be as follows. When self-test is completed, turn off the analyzer and
switch the toggle switch back to the left end.
2.2.1 LCD Screen Self-test
First light up then turn off the pixels from left to right. Then repeat the process on screen from
top to bottom. Damaged pixels should be easy to identify through this process.

2.2.2 Printer Self-test

When there is no paper in printer, paper status on screen should be “End”. Otherwise, the paper
status sensor is not functional.
After installing the paper, please confirm the paper status on screen reads “OK”. Otherwise, the
paper status sensor is not functional.
Press “PRN” to do a test print. Please check the whole width line at the last. If any part is
missing, the printer is malfunctioned.

2.3 Software Upgrade

2.3.1 Upgrade Preparation
Upgrade software through running PC programs and transferring the upgrade package to
equipment through the serial port. Please get these ready:
 Flash Loader Demonstrator V2.0.0
 Top main board and/or bottom main board operating system software
 Serial Cable that comes with the analyzer
Install Flash Loader Demonstrator V2.0.0
Run Flash_Loader_Demonstrator_V2.0_Setup.exe

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Service manual LAURA M

Click “Finish” to complete installation.

After installation, go to “start > All programs”, a new program is installed.
“STMMicroelectronics>Flash Loader Demonstrator>Flash Loader Demo” is the shortcut of the
upgrading software, Flash Loader Demonstrator V2.0.0.

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Service manual LAURA M
Shut down the analyser, connect one end of the serial cable to the analyzer, the other end to a
PC. Pull out the waste stripe box to find the upgrading toggle switch as shown on figure below,
there are three positions for the switch, when facing the analyzer:

Toggle Switch Left Middle Right

Equipment Regular operation Upgrade bottom board Upgrade top board
status
2.3.2 Bottom Main Board Upgrade
Set the upgrading toggle switch to the middle. Turn on the analyzer. Run “Flash Loader Demo”
on PC. Choose the correct PC serial port (COM port). Set parameters as follows and click
“NEXT” to continue:

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Service manual LAURA M
After Flash Loader Demo has recognized the CPU of the bottom main board, shows the
following window. Click “NEXT” to continue.

Flash Loader Demo shows recognized CPU type (STM32_High-density_512K) as follows:

Choose “Erase all pages” to clear the FLASH ROM and upgrade.

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Flash Loader Demo prompt user to download the necessary software:

Click the button circled in the picture to get this window. Find the operating system software that
needs to be downloaded (*.hex file). First set the file type to “*.hex”, then choose the hex file
needs to be downloaded and click “Open”. Click “NEXT” to continue.

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Click “NEXT” again in the next window.

Start downloading:

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Service manual LAURA M
When download is completed

Click “Finish”. Turn the power off for the analyzer. Then push the upgrading toggle switch back
to the left to complete upgrading of the bottom board.
2.3.3 Top Board Upgrade

Set the upgrading toggle switch to the right. Turn on the analyzer. Run “Flash Loader Demo” on
PC. Choose the correct PC serial port (COM port). Set parameters as follows and click “NEXT”
to continue:

After Flash Loader Demo has recognized the CPU of the bottom board, shows the following
window. Click “NEXT” to continue.

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Flash Loader Demo shows recognized CPU type (STM32_High-density_512K) as follows:

Choose “Erase all pages” to clear the FLASH ROM and upgrade.

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Service manual LAURA M

Flash Loader Demo prompt user to download the necessary software:

Click the button circled in the picture to get this window. Find the operating system software that
needs to be downloaded (*.hex file). First set the file type to “*.hex”, then choose the hex file
needs to be downloaded and click “Open”. Click “NEXT” to continue.

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Service manual LAURA M

Click “NEXT” again in the next window.

Start downloading:

When download is completed:

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Standard operation procedure 294-1 Date of validity: 14.02.2012
Service manual LAURA M

Click “Finish”. Turn the power off for the analyzer. Then push the upgrading toggle switch back
to the left to complete upgrading of the bottom board.
Warning: When upgrading an analyzer, please upgrade bottom board then upgrade top board.
Please avoid upgrade only one of the two boards.

2.4 Serial Port Communication

2.4.1 Connection
The serial cable in the accessories supports connection between PC and the RS-232 port. Use
DB9 Male on the analyzer port. Use DB9 Female on the PC port. Refer to figure 2.1 for
connection:
Analyzer port DB9 Male PC port DB9 Female
2 2
3 3
5 5
2.4.2 Specifications
Parameter Specification
Communication Asynchronous serial communication
mode
Communication TXD, RXD, GND
signals
Allowed baud rates 9600图19200, 38400, 57600bps
Parity bit Odd
Data length 8 Bits
Stop bit 1 Bit

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Service manual LAURA M
2.4.3 Data Transfer
When the analyzer transfer data to a PC, the analyzer is the sender, which does not receive data,
the PC is the receiver, which does not send data.
Data transfers as “frames”. Every frame is a complete test report. One frame is consists of
several lines. Each line ends with ASCII character 0DH and 0AH. Every line is consists of one
or two fields. Fields are separated by ASCII character 09H.

See table 2.2 for detailed data on a frame.

Line Field 1 Field 2 Description
1 Date, 20XX-XX- Only 1 field
XX
2 Time, XX:XX:XX Only 1 field
3 Sample Number, XXX Only 1 field
4 Blank
5 Name of item 1 Item 1
6 Name of item 2 Item 2 result
7 Name of item 3 Item 3 result
8 Name of item 4 Item 4 result
9 Name of item 5 Item 5 result
10 Name of item 6 Item 6 result
11 Name of item 7 Item 7 result
12 Name of item 8 Item 8 result
13 Name of item 9 Item 9 result
14 Name of item 10 Item 10 result
15 Name of item 11 Item 11 result Blank if using 10-item strip

In test reports, characters “±” and ”µ” are shown as “+-” and “u”.
PC does not respond to analyzer after receiving a frame of report.

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3 Disassemble

3.1 Analyser Structure

3.1.1 Exterior

Figure 5.1 Equipment Structure (Front view)

Figure 5.2 Equipment structure (Back view)

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Standard operation procedure 294-1 Date of validity: 14.02.2012
Service manual LAURA M
3.1.2 Component Layout
Laura M Urine Analyzer
Thermal Printer LCD Touch panel Component Layout
图A图图图图图图 图B图图

Top main board

Top part

Serial port to PC Parallel port to Printer

Bottom main Board

RGB sensor
5V
Mechnical transportation
Parts Waste stripe
Sensors box
Bottom part
Switch Power

12V Motor

Switch Power input

3.1.3 Electrical Diagram

Thermal Printer LCD Keyboard Laura M Urine Analyzer

图A图图图图图图 图B图图 Diagram

20
8
20

Top boardCPU Top part

2

Serial port to PC Parallel port to Printer

Sensor group includes 7 sensors and
Bottom Board CPU RGB sensor switches
1. Belt sensor with 3-core cable
5V 1
2 2. Hand motion sensor with 4-core cable
Mechnical transportation Waste 3. Confirmation sensor with 3-core cable
10 components strip box 4. Reference sensor with 3-core cable
Power adapter Sensors 5. Waste box full sensor with 2-core cable
12V 6. Feeding plate sensor
GND 7. Waste box sensor
(5,6,7 share a 6-core cable)
2
Motor

Switch Power input

L GND N Bottom Part

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Service manual LAURA M
3.1.4 Power Diagram

Power Diagram

Power input with

fuse
Dual Switch

Switch Power
图NED-50A图
L ～ 5V
～
N 12V
GND GND

Shell of the
Ground power is
protection grounded

3.1.5 Insulation Diagram

OP-1550, 1530B/A Urine

Analyzer Insulation Diagram
Plastic shell

insulated
metal shell

Low voltage
L circuit
Power
adapter
N

Metal components Metal structure

inside

GND
protection

Accessible from outside

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3.2 Overall Structure Diagram

1 2 3 4 5 6

24
7

23 8

22 9

21 10

20 11

19 18 17 16 15 14 13 12

Number
No. Description Specification
Required
1 Top Shell 1
2 LCD Frame 1
3 LCD Model 1
4 LCD mounting board 1
5 Part of Scan motor 1
6 Thermal Print Head 1
7 Printer Driving board 1
8 Bottom main Board 1
9 Part of Paper Feeding motor 1
10 Motor Driving Board 1
11 Bottom Shell 1
12 Waste Stripe Box 1
13 Waste Stripe box full Sensor 1
Transmitter and Receiver
14 Feeding Plate Position Sensor 1
15 Waste Stripe Box Position Sensor 1
16 RGB Sensor (Scanner) 1
17 Sliding part for RGB Sensor 1

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Service manual LAURA M
18 Hand Motion Sensor 1
19 Stripe Carrier (position for stripes) 1
20 Feeding Plate 1
21 Stripe Carrier Sensor 1
22 Stripe Confirmation Sensor 1
23 Switch Power 1
24 Top main Board 1

3.3 Feeding Plate

Feeding plate is an important component of the analyzer. Keeping the feeding plate in good
condition is crucial to accurate testing. Please keep the feeding plate clean to avoid
contamination. Avoid accumulating urine on the plate, which may cause resistance to the
transferring of the stripes. Feeding plate must be installed correctly or the error “Plate Position
Error” would show on screen.

Please be careful when installing the plate. First insert the longer side (shown in figure 5.10) into
the channel. Then insert the short side in to the channel and carefully slide the plate inwards until
it reaches the end. Please do not apply force downwards when sliding the plate, otherwise the
plate would bent in the middle and cannot be held by the screws. Shown in figure 5.11, one of
the screws is not in position so the stripe may not be fed to the correct scanning position.

Plate Wall
Longer side
Tendons on plate

Figure 5.10
Feeding plate should be washed with clear water daily. Especially, the nine tendons on the plate
need to be cleaned to keep accumulated sample from affecting the feeding of strips.

Common problems:
Incorrectly installed plate: if the error indicates plate in not installed correctly, pushing it farther
into position.

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Occasionally, the error message is not shown but the one slot in the middle has no screw slide in
(Figure 5.11). In this case, it is impossible to carry the stripes to position (the position of stripe
carrier relative to the plate is shown in figure 5.12). The solution is simply pull out the plate out
then slide in again. Be careful not to press the handle down to avoid the other end tilting up.

Figure 5.11

Figure 5.12
Another common malfunction is caused by dirty plate, which keeps stripes from being carried
freely to position. Wrong position of the stripe is illustrated in figure 5.13. This would cause
incorrect readings and error message “stripe error”. The solution is to wash and clean the feeding
plate especially the wall and tendons.

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Figure 5.13

3.4 Waste Stripe Box

Waste strip box is used to collect used stripes after tests. Normally it can store up to 200 stripes,
which matches the daily usage of most users. The capacity may vary due to random ways of
piling up the waste stripes. To avoid contamination and humidity, it is recommended to clear the
waste box daily.

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Waste box full

receiver

Waste stripe box

Waste box full

transmitter

Figure 5.14
The full status of the waster box is monitored by infrared transmitter and receiver, as shown in
figure 3.14. When the transmission is blocked, he operator will be told that the waste box is full.
Humid and waste stripe can pollute the infrared transmitter and receiver, which may causes false
alarm. When false alarm happens, pull out the waste box and clean the transmitter and receiver
with ethanol cotton ball (figure 5.15). The receiver is polluted more often.

Infrared Receiver
transmitter

Figure 5.15
An inching switch checks the position of the waste box (figure 5.15). The switch is accessible by
hand. Normally the lifetime of inching switch meets the needs. If error “Waste box missing”
shows up, push the waste box farther to position. If the error remains, pull out the waste box and
test the inching switch by hand or tools to see whether the switch is functional. If the switch is
functional (error can be eliminated with hand or tools), the switch might be loosen. Simply adjust
the switch to make sure the waste box firmly touches the switch to solve the problem. If the error
cannot be eliminated by press the switch by hand or tools, open the top shell and use a multi-
meter to test whether the two wired terminals of the switch are connected. If the terminals are
connected, unstable connection or other parts might cause the error. If the terminals are not
connected, the inching switch needs to be replaced.

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If there is no spear inching switch, this fix can be implemented later. User can bypass the error
by set the switch off through software. Then the waste box error would not show up. In this case,
user have to take care of the waste box to make sure it is installed in position and clear the box
frequently to avoid too many waste stripes to affect the work of the equipment.

3.5 Open the Top Shell

The analyzer has two major parts: top part and bottom part. The two parts are bolted with seven
M3X12 screws and one M3X8 screw (figure 5.16). The largest circle indicates the M3X8 screw.
The rest are M3X12 screws.
 Clean working surface and lay soft material on the surface
 Unplug power and cables from analyzer and place it upside down on the soft surface
 Unscrew the eight screws with a magnetic Phillips screwdriver and keep the screws
carefully
 Hold the top and bottom part and turn the analyzer back to regular position
 Hold only the top shell and carefully open the top shell to back
 Stand the top shell at the backside of the bottom part. Be careful with the 2-core 5V power
cord and the 4-core data transmission cable connecting the two boards

Figure 5.16

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3.6 Top Part Components
Top part is shown in figure 5.17

7 2

6 3

4
5

Figure 5.17

Number
No. Description Specification
Required
1 Top Shell 1
2 5V Power Cord 1
3 Printer Board 1
4 LCD 320X240 1
5 LCD mounting board 1
6 Data Transmission Cable 1
between Top and Bottom Board
7 Top main Board 1

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3.7 Bottom Part Components
Bottom part is shown in figure 5.18
1 2 3 4 5 6 7
8

25
9

24 10

11
23

12

13

22
14

15
21 20 19 18 17 16

Figure 5.18

Number
No. Description Specification
Required
1 Base 1
2 Power Switch PLB-012F3 1
3 Dual Fuse Power Inlet 0171-2-CW 1
4 Motor Part for Scanner 1
5 Parallel Port 1
6 Serial Port 1
7 Button Cell 2032 1
8 Bottom main Board 1
9 Motor Driver Board 1
10 Starting position Sensor
1
Board
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Number
No. Description Specification
Required
11 Stripe Feeding part 1
12 Waste Box Full receiver 1
13 Plate Position Screws 1
14 Waste Stripe Box 1
15 Waste Box full transmit
1
LED
16 Secondary Track 1
17 Main Track 1
18 Scanner Belt and Gear 1
19 Hand Motion Sensor 1
20 Scanner and its Carrier 1
21 Feeding Plate 1
22 Stripe Feeding Belt and
2
Carrier
23 Stripe Confirmation Board 1
24 Protection Ground 1
25 Switch Power NED-50A 1

3.8 Sensors
The mechanical motion is tracked by seven photoelectric switch and inching switches. Detailed
structure and description are as follows:
Name Type Description Possible Error Solution
Stripe Slot Coupler Can be seen after Cannot detect Check whether
Carrier removing the feeding the carriers the carriers can
Sensor plate. Used to track block the slot
the motion of coupler. Use
carriers and status of other object to
the belt. Figure block the slot
5.20 coupler to check
the functionality
of the slot
coupler.
Stripe Reflect Coupler Can be seen after Cannot detect Adjust height to
Confirmation opening the top Stripe check
Sensor shell. Used to detect functionality.
stripes moving Replace if
towards scanning necessary.
position. Figure 5.21
Scanner Slot Coupler Can be seen after Scanner passes Block the sensor
Head Sensor opening the top over starting to test whether it
shell. On the scanner position is functional.
tracks. Used to track Replace if
the position of the necessary.

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scanner and the
starting position.
See figure 5.21
Feeding Inching Switch Remove the waste Unstable Test the switch.
Plate Sensor box and look into the connection. Replace if
analyzer, the switch Plate is in necessary.
can be seen at the position but
upper left side. It is cannot be
used to check detected.
whether the plate in
installed correctly
Figure 5.21
Waste Box Inching Switch Can be seen after Unstable Test the switch.
Sensor pulling out the waste connection. Replace if
box (on the upper Waste box is in necessary.
left side). Used to position but
test whether the cannot be
waste box is detected.
installed correctly.
See figure 5.22
Waste Box Infrared LED and Can be seen after False alarm Clean LED
full sensor Receiver pulling out the waste when the box is transmitter and
box (on the left and not full receiver.
right side). Used to Replace if
test whether the necessary.
waste box is full.
Usually the capacity
is around 150 to 200.
See figure 5.21, 5.22
Hand Motion Infrared Look towards the Sensor not Put hand close to
Sensor Transmitter and direction of inserting sensitive or the sensor, wave
Receiver the feeding plate, cannot test hand over the sensor.
sensor is on the motion If there is
right. Used to detect respond, the
the motion of sensitivity of the
placing the stripe, sensor is low. If
and start the feeding there is not
the stripe to scanning response, the
position. When the sensor is not
strip confirmation functional.
sensor detects the Replace if
strip, the new strip is necessary.
confirmed. Then the
test invalid,
otherwise, the hand
motion is considered
invalid. Figure 5.21

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Standard operation procedure 294-1 Date of validity: 14.02.2012
Service manual LAURA M

Carrier
sensor

Figure 5.20

Starting position sensor

Stripe confirmation
sensor
Infrared
receiver

Infrared
LED
Transmitter
Feeding plate
Hand motion sensor
sensor

Figure 5.21

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Erba Lachema s.r.o.
Standard operation procedure 294-1 Date of validity: 14.02.2012
Service manual LAURA M

Waste box sensor Infrared LED Transmitter Infrared receiver

Figure 5.22

3.9 Feeding Mechanism

1 2
12 0 3
4
5
11

6
10
7

9
8

Figure 5.23
Structure: track, strip feeding system, scanning system
Number Name Specification Quantity
1 Scanner Motor part 1
2 Scanner Main Gear 1
3 Stripe Feeding Motor part 1
4 Sliding Component 1
5 Secondary Track 1

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Erba Lachema s.r.o.
Standard operation procedure 294-1 Date of validity: 14.02.2012
Service manual LAURA M
Number Name Specification Quantity
6 Main Drive Axis 1
7 Main Track 1
8 Driven Gear 1
9 Mechanical Frame 1
10 Driven Axis 1
11 Belt for moving stripes 2
12 Stripe Confirmation Sensor 1
Mounting Position

4 Adjustment

4.1 User Threshold Adjustments

Threshold adjustment enables users to adjust the sensitivity of all testing items.
Turn on the analyzer and watch the progress bar under the logo. When the progress bar is almost
full, press the 10mm x 10mm area on the upper left corner of LCD. The backdoor window would
pop up asking for password:

Enter the 6-digit password “011119” with number keyboard, then press “ √ ” to access
threshold adjustment backdoor.

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Standard operation procedure 294-1 Date of validity: 14.02.2012
Service manual LAURA M

Press items need to be adjusted. Here we use BLD as an example:

This window lists all the arbitrary system of the item and the threshold value between each two
thresholds. Note most of the threshold table is decrement, while some items are increment, such
as SG and GLU.

Choose threshold to be changed and enter the new threshold with the small keyboard. Then press
“√” to enter.

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Service manual LAURA M

After all changes, return to this window. Press “√” to confirm changes, or press “X” to cancel the
changes.

Return to main menu:

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Standard operation procedure 294-1 Date of validity: 14.02.2012
Service manual LAURA M
Press “save” to save all threshold settings to the Flash ROM. These settings are not lost after
power off. After restart, all displaying, printing, and transferring of the new reports and saved
reports are produced with the new thresholds.

There is also a “load default” option. Press “load default” to restore threshold settings which are
set by manufacturer.

Note this is a risky operation. Once pressing “Yes”, all default threshold settings are
restored. However, the default thresholds may not be suitable for the present use. Only use
default settings when necessary!

5 Maintenance

5.1 Daily Maintenance and Cautions

Do not place the analyzer under direct sunlight, which may affect testing accuracy.
Often use dry soft cloth to clean the analyzer. If the surface is dirty, use a little water to wipe the
analyzer. Do no use any gasoline, paint dilution, benzene compounds, ethanol, or any other
organic solvents to clean the analyzer. These chemicals may cause deformation, peel off paint,
affect normal operation, or appearance.
Do not clean the LCD with water. Only use dry soft cloth to clean the LCD.
Considering the physical property of the stripes, please avoid using it under high or low
temperature to ensure the accurate testing results. (Ideal working temperature is 10 – 30 °C).
5.1.1 Feeding Plate
The most critical maintenance is to keep the plate from deformation and clean. Please see the
section about feeding plate.
5.1.2 Carrier Belt
Plastic carriers are in contact with urine samples during testing. Sample may accumulate on the
plate thus create resistance to strips and produce unpleasant smell and looks. In this case, pull out
the plate and clean it with soft brush and water or basic cleaner of low concentration.

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Erba Lachema s.r.o.
Standard operation procedure 294-1 Date of validity: 14.02.2012
Service manual LAURA M

Figure 7.1
5.1.3 Waste Stripe Box
Clean daily
5.1.4 Waste liquid plate
Clean when necessary

5.2 Sterilization
1. Use one of the three formulas to make disinfectant:
 2% Glutaral Solution Cidex. This is a consumer product sold in market. Refer to the tag for
usage.
 Or 0.05% sodium hypochlorite solution: add 1ml of sodium hypochlorite solution (or Clorox
Bleach) to 99 ml water to make 1:100 dilution
 Or isopropyl alcohol (70% - 80%)
2. Pour disinfectant into a container. Submerge the waste strip box and feeding plate into the
disinfectant. Do the same for liquid plate is necessary.

3. Soak for 10 minutes, take out, and dry with paper towel.

5.3 Periodic Cleaning

If the feeding plate and waste box is rather dirty, following these steps to clean:
1. Take out the feeding plate and waste box
2. Use Cotton Tipped Applicators or other material to dip in 0.1N NaOH solution, clean the
channels of feeding plate and waste box.
3. Use distilled water to rinse the feeding plate and waste box.
4. Dry the feeding plate and waste box with water absorbent material. Make sure to clean and
dry the channels.
5. Reinstall the feeding plate and waste box.

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Service manual LAURA M

6 Error Messages and Solutions

6.1 Error Code Table

Error messages are displayed when the analyzer has malfunctions or is operated
incorrectly. Errors may problems to some or all functions. Information about error
messages are as follows:

Error Message Table

Error Code Error Description Problem and Solution
E01 System software Error System memory error. System software missing
causing the analyzer cannot operate. Try to upgrade
the software. If upgrade fails, consider replace
bottom main board or contact manufacturer.
E02 System Data Error Stored system check and calibration data is lost. The
analyzer cannot operate. Please contact manufacturer
for fixing.
E03 Threshold Data An error has occurred on system data related to
Error strips. Please contact manufacturer for fixing.
E10 Carrier Sensor Error Feeding belt is functional but the carrier sensor
cannot detect the carriers. Take the feeding plate out
to see whether the carrier sensor is loosen or any
wire is disconnected. Also check the position of
sensor relative to the carriers. Then use objects to
block the sensor to see if that can be detected. If all
these tests cannot fix the problem, please contact
manufacturer for fixing.
E11 Feeding Belt Error Feeding belt does not feed correctly and the carrier
sensor detects abnormal movements. This is often
caused by increased carrier movement period – carry
speed slows down or inconsistent. Listen to the
carrying movement to see whether these are any
abnormal sound and observe for periodic resistance
occurrence. Also check for pollution to the stripe
feeding system. If all the steps cannot solve the
problem, please contact manufacturer for fixing.
E12 Stripe Sensor Error The movement and position of the stripe is normal.
However the stripe confirmation sensor cannot detect
the stripe. Open the top shell to check the position
and connection of the stripe confirmation sensor.
Take a stripe and move it across the sensor at the
same time as the stripe on the feeding plate, but
closer to the sensor. If the sensor is respond to this
stripe, the sensitivity of the sensor is low. Try lower
the sensor temporarily. If these are still no respond,
please contact manufacturer for fixing.

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Service manual LAURA M
Error Code Error Description Problem and Solution
E21 Starting Position Error Open the top shell to check the position and
connection of the starting position sensor. If no
problem found, turn on the analyzer and observe the
movement of the scanner head. The scanner head
should stop once the light-block pass the coupler. If
it does not stop, the sensor may be failed. To test the
sensor, use a larger piece of object to block the
sensor, start the analyzer. If the motor stops once the
sensor is blocked, the problem would be the position
of the light-block. Adjust the position of the light-
block and do tests again. If other objects cannot
block the sensor to stop the motor, the sensor may
need to be replaced. Please contact manufacturer for
fixing.
E22 Scanner Head Motion Open the top shell, start the analyzer to observe the
Error motion of the scanner head. If the starting position is
detected correctly but the movement of the scanner
head is abnormal, listen carefully for any noise.
Loosen the screws on scanner head that holds the
synchronization belt, move the scanner head back
and forth with hand to feel any resistance. If there is
resistance, apply some lubricating oil and move it
with hand again until the movement is consistent and
smooth. Then fasten the screws and observe again, if
this fix the problem, the problem was the motor had
insufficient power to overcome the resistance. If the
above step does not fix the problem, the motor or
driver might be broken. Please contact manufacturer
for fixing.
E23 Brightness Error Open the top shell and check whether the white
reference chip is loosen or contaminated. If it is
loosen, apply appropriate adhesive to fasten the chip.
If it is contaminated, use water to clean it. If it looks
normal, power on and observe whether there is bright
light laminating the chip in a very short time.
Possible problems: the light source is outdated, the
light source is not well connected, or the receiver
(RGB receiver) is not receiving correctly.
Check the connection of cables and circuits. If the
problem cannot be fixed, contact manufacturer for
fixing.
E24 Background Light Error First, eliminate the possibilities that the top shell of
the analyzer lid broken or there is bright light source
nearby. If not, open the top shell, power on and
observe whether there is bright light laminating the
chip. If there is the bright light on the chip in a very
short time, contact manufacturer for fixing.

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Service manual LAURA M
Error Code Error Description Problem and Solution
E30 Printer Out of Paper The printer is out of paper when reports are to be
printed
E31 Feeding Plate Incorrectly Confirm the plate is installed in position. Refer to
Installed section 8.2 to try reinstalling the plate.
E32 Feeding Plate Needs to Too much urine sample is accumulated on the plate.
be Cleaned Refer to section 8.2 to clean the plate.
E33 Waste Box Incorrectly Confirm the installation of the waste box. Try
Installed reinstalling the waste box.
E34 Waste Box Full Take the waste box off, clear the used strips, and
reinstall.
If there are no so many stripes in the box or empty,
the stripe full sensor maybe in malfunction. Try to
clean the receiver. If the problem cannot be fixed,
contact manufacturer for fixing.
E42 Stripe Position Incorrect Stripe position incorrect on the feeding plate causing
the testing failure. A failure report is generated and
saved in the memory.
Complete the test, then locate the failed sample and
redo the test.

6.2 Other Malfunctions and Solutions

Errors Possible Problems Solutions
Analyzer does 1.Loosen power 1.Check power cord and plug
not turn on connection 2.Replace fuse
2.Fuse burnt 3.Replace power component
3.Power switch fail
LCD no display, 1.Top board lost power 1.Open the analyzer and
but the feeding (LCD no power) check the 5V power supply
belt is moving 2.LCD fails 2.Replace LCD
3.Top main board fails 3.Replace top main board
“Communicatio 1.Communication fails 1.Power off then power on
n Fail” display between top and bottom 2.Check the position of the
on the screen, or main board inching switches
start self testing 2.Inching switch 3.Check/replace the strip
procedures malfunction feeding board and motor
while the 3.Driver board or motor 4.Check/replace bottom main
feeding belt is fails board
not moving 4.Bottom main board fails

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Service manual LAURA M
Errors Possible Problems Solutions
Printer does not 1. printer set to “Do not 1.Set printer settings to
print or print print” “print”
incorrectly 2.Printer out of paper 2.Install a new paper roll
3.Paper feeding motor and 3.Check paper feeding motor
driver error (print a and driver
horizontal line) 4.Replace printer
4.Printer fails 5.Replace printer board
5.Printer board fails 6. Replace top main board
6.Top main board fails
Serial port 1.Serial port incorrectly 1.Check cable connection
communication connected or used wrong and use the appropriate
fails cable cables
2.Wrong serial port (COM) 2.Try other serial ports
used on the user terminal (COM)
3.Baud rates on the user 3.Change the baud rates of
terminal mismatches the programs on the user
with the analyzer terminal
4.Bottom main board fails 4.Replace bottom main board

7 Safety precautions
Only trained service engineers can test and repair this instrument. They must keep all
local safety rules and precautions, especially at work with electrical parts and wits strip
and patient samples, which are potentially biohazardous material.

8 Table of revisions
Release Description Chapter Valid by
1.0 New document - 02/14/2012

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