Epidemiology - Upper Epigastric Pain

Download as docx, pdf, or txt
Download as docx, pdf, or txt
You are on page 1of 2

(SLIDE 1)

ACUTE CALCULOUS CHOLECYSTITIS

results from obstruction of the cystic duct, usually by a gallstone, followed by distension and subsequent
chemical or bacterial inflammation of the gallbladder

 Right upper quadrant paint


 Anorexia
 Nausea
 Vomiting
 Fever

95% of people with acute cholecystitis have gallstones (calculous cholecystitis)

5% lack gallstones (acalculous cholecystitis)

(SLIDE 2)

Gallstones are quite prevalent in most Western countries. Gallstone formation increases after age 50. In
the United States, the third National Health and Nutrition Examination Survey (NHANES III) has revealed
an overall prevalence of gallstones of 7.9% in men and 16.6% in women. The prevalence was high in
Mexican Americans (8.9% in men, 26.7% in women), intermediate for non-Hispanic whites (8.6% in men,
16.6% in women), and low for African Americans (5.3% in men, 13.9% in women).
(SLIDE 3)

Gallstones are formed because of abnormal bile composition. They are divided into two major types:

A. Cholesterol stones
 account for >90% of all gallstones in Western industrialized countries
 usually contain >50% cholesterol monohydrate plus an admixture of calcium salts, bile
pigments, proteins and fatty acids
B. Pigment stones
 composed primarily of calcium bilirubinate
 they contain <20% cholesterol and are classified into “black” and “brown” types, the
latter forming secondary to chronic biliary infection

You might also like