Doc1 Obstractive Jaundice
Doc1 Obstractive Jaundice
Doc1 Obstractive Jaundice
Obstructive jaundice (surgical jaundice) in simple terms means the outflow of bile has been obstructed
anywhere from the liver to the duodenum.
A correct pre-operative diagnosis in almost always possible today because of advances in imaging
techniques over the decades.
Removal of block relieves the symptoms and often results in cure. In present day world surgical jaundice
has become more of a medical entity as most of the obstructive jaundice cases are managed by
Gastroenterologists by ERCP or by stenting rather than by surgeons.
There are varied causes of obstructive jaundice, but it is most commonly due to choledocholithiasis (also
called bile duct stones or gallstones in the bile duct) – presence of a gallstone in the common bile duct
Other causes like, malignancies such as cholangiocarcinoma, periampullary and pancreatic cancers, and
benign stricture including chronic pancreatitis have become increasingly prevalent.
There as also rise in iatrogenic causes of obstructive jaundice, like injury of biliary tract and cholangitis
with the increase of invasive procedures performed on the biliary tract.
Biliary tract disorders can be significantly found in worldwide population, and the quite majority of cases
are attributable to choledocholithiasis. 20% of persons older than 65 years in USA have gallstones and
around 1 million newly diagnosed cases of choledocholithiasis are reported every year. Patients with
obstructive jaundice usually present with complain of yellow skin and eyes, pale stools, dark coloured
urine, jaundice, and pruritus. Abdominal pain often misleading for diagnosis– some patients with
choledocholithiasis have painless jaundice, whereas some patients with hepatitis have distressing pain in
the right upper quadrant. Malignancy often associated with the absence of pain and tenderness during
the physical examination.
Patients with obstructive jaundice have tendency to develop nutritional deficits, infectious
complications, acute renal failure, and impairment of cardiovascular function. Other adverse events
such as coagulopathy, hypovolemia, and endotoxemia can be insidious and significantly increase
mortality and morbidity. An accurate diagnosis can usually be made with combination of different
approaches like, history, physical examination, and biochemical tests, and when appropriate
cholangiography and liver biopsy and observation of the patient's course.
Early and precise detection of etiology of obstructive jaundice can help surgeons to accurately manage
such patients and thus will improve quality of life of patient and improving the survival rates among the
patients with malignant pathology. Hence, present study was undertaken study the clinical profile of
patients with obstructive jaundice..
Pathophysiology
Anatomy
What’s a T-Tube? It’s a t-shaped tube that is placed in the bile duct to help drain
excessive bile and can be used for testing to assess the biliary tree and ducts.
WHY? This helps make sure the t-tube is draining because they can become
blocked, leak bile into the abdominal cavity (leading to peritonitis), or there is
excessive drainage (bleeding etc.).
Fresh post-op (1-2 days): drainage starts out with some blood and then
progresses to a greenish/yellow/brown liquid drainage.
o watch for extremely thick, bad smelling drainage with a fever or extremely
bloody like bright red blood that looks fresh)
Inspect skin and abdomen frequently
Change dressing (keep it dry and clean)…bile is very harsh on the skin
Monitor for bile leakage into abdomen (bile peritonitis)
o Assess how well patient tolerated the t-tube being clamped…if patient
develops abdominal pain, nausea vomiting etc. unclamp it and notify MD.
o Clamping the t-tube tell us how well the bile duct is working to deliver the
bile and if the patient will be able to tolerate not having the t-tube once it’s
removed.
REFERENCES
1. Shah R, John S. Cholestatic Jaundice (Cholestasis,
Cholestatic Hepatitis). In: StatPearls. Treasure
Island (FL): StatPearls Publishing; 2019. Available
at: https://www.ncbi.nlm.nih.gov/books/NBK48-
2279/. Accessed on 16 January 2019.
2. Bertani H, Frazzoni M, Mangiafico S, Caruso A,
Manno M, Mirante VG, et al. Cholangiocarcinoma
and malignant bile duct obstruction: A review of last
decades advances in therapeutic endoscopy. World J
Gastrointest Endosc. 2015;7(6):582–92.
3. Clarke DL, Pillay Y, Anderson F, Thomson SR. The
current standard of care in the periprocedural
management of the patient with obstructive
jaundice. Ann R Coll Surg Engl. 2006;88(7):610–6.
4. Wang L, Yu WF. Obstructive jaundice and
perioperative management. Acta Anaesthesiol
Taiwan. 2014;52(1):22-9.
5. Lipsett PA, Pitt HA. Acute cholangitis. Front
Biosci. 2003;8:s1229-39.
6. Sinanan MN. Acute cholangitis. Infect Dis Clin
North Am. 1992;6:571-99.
7. Lipsett PA, Pitt HA. Acute cholangitis. Surg Clin
North Am. 1990;70:1297-312.
8. Liu YH, Qiu ZD, Wang XG, Wang QN, Qu ZQ,
Chen RX, et al. Praziquantel in clonorchiasis
sinensis: a further evaluation of 100 cases. Chin
Med J (Engl). 1982;95:89-94.
9. Khuroo MS, Zargar SA, Mahajan R. Hepatobiliary
and pancreatic ascariasis in India. Lancet.
1990;335:1503-6.
10. Bonheur JL, Ells PF, Talavera F, Anand BS, Kapoor
VK, Minocha A. Biliary Obstructi. MedScape.
Available at: https://emedicine.medscape.com/
article/187001-overview. Last accessed on 16
January 2019.
11. Shrikhande SV, Barreto G, Shukla PJ. Pancreatic
fistula after pancreaticoduodenectomy: the impact
of a standardized technique of pancreaticojejunostomy. Langenbecks Arch Surg. 2008;393:87-
91.
12. Anand S, Panda C, Senapati AT, Behera MR, Thatei
C. A study on incidence, clinical profile, and
management of obstructive jaundice. J Evid Based
Med Healthc. 2016;3:3139-45.
13. Shehu K, Babameto A, Xinxo S, Shehu B, Duni A,
Taci S, et al. Relation between the Demographic and
Clinical Characteristic and the Etiology of
Obstructive Jaundice. Mediterranean J Med Sci.
2015;2:1-8.