Antibiotics

Pharmacological Discovery/Development Other/Anything

Student Name/Contributer Generic Name Brand Name Category Date Method of Action Medical Uses Common Side Effects Interesting?

Concerns about allergic reactions, such as skin rash Helpful against both Gram
(hives), swelling of lips, tongue, face, etc. Not + & 1 bacteria (and
Inhibits Bacterial DNA Active against acute bacterial recommended for people under 18. Also reported effective against MRSA
Mr. M Delafloxacin Baxdela® Fluoroquinolone 2017 replication skin infections nausea, vomiting, headache. (Resistant strains))
Inhibits DNA-gyrase Acute bacterial sinusitis;
in organisms that acute bacterial
partakes supercoiled exacerbation of chronic
DNA and mentions bronchitic; nosocomial
the breakage of DNA pneumonia; community- This antibiotic is
strands. Also acquired pneumonia; - Abdominal pain bactericidal (primarily)
minimizes toxicity and complicated skin and skin - Nausea, vomiting when at concentrations
Quinolone makes sure there is structure infections; - Diarrhea equivalent or slightly
Antibiotics, third- ofloxacin antibacterial uncomplicated skin and - Nervous system problems (headaches, greater than any
generation potency. skin structure infections dizziness, tremor, or confusion) inhibitory
Julie Bui Levofloxacin Cravit and Levaquin (fluoroquinolone) 1987 (mild to moderate); concentrations.
Tigecycline injection used
to treat certain serious
infections including
community-acquired
pneumonia (a lung
infection that developed in
a person who was not in
the hospital), skin
infections, and infections
Tetracyclines are of the abdomen (the area
protein synthesis between the chest and the
inhibitors primary waist). Major health
targeting the 30S concerns: photosensitivity,
ribosome. They are deposition in developing Nausea, vomiting, headache, dizziness, or
Tetracyclines/Glycy essentially bones, and teeth. pain/swelling
Sovannita Kheung Tigecyline Tygacil lcylines 2009 bacteriostatic.
Cefalexin is effective
against many different
infections such as
pneumonia. Not only is it
effective against There are many possible side effects Cephalexin
By interfering with pneumonia, it is also used can cause: nausea, diarrhea, vomiting, heartburn,
the formation for infections of the stomach pain, rectal or genital itching, dizziness,
bacteria's cells walls, respiratory system, bones, extreme tiredness, agitation, confusion, headache,
which weakens and skin, ears, genitals, urinary and joint pain. Some more serious side effects
ruptures the walls, tracts, and on a few include rashes, itching, hives, swelling, difficulty
Cefalexin is then occurrences those with breathing, wheezing, fever, sore throat, chills, and
Cefalexin removing and killing heart conditions. hallucinations.
Jessica Le (Cephalexin) Keflex and Keftab Cephalosporins 1967 the infection.
Doxycycline is used to
treat many different
bacterial infections, such
as acne, urinary tract
infections, intestinal
infections, respiratory
infections, eye infections,
gonorrhea, chlamydia,
syphilis, periodontitis (gum
disease). It can treat and
The method of action prevent infections. It can
for doxycycline is to also treat rosacea and Common side effects of doxycycline are weight
stop the growth of severe acne, and prevent loss, nausea, vomiting, diarrhea, skin sensitivity to
Niki Domasz Doxycycline Vibramycin, Monodox, Acticlate, Atridox,
Tetracycline Avidoxy, Doxy, Doxycin,
1960's Doryx, Oracea, Periostat,
bacteria. malaria. Adoxa, Ocudox, and Doryxhives
sunlight, MPC.anemia, and vaginal yeast infection.
 Antibiotics
Pharmacological Discovery/Development Other/Anything
Student Name/Contributer Generic Name Brand Name Category Date Method of Action Medical Uses Common Side Effects Interesting?
Penicillin antibiotics were
among the first nausea,
medicatons to be effective vomiting,
against many bacterial diarrhea,
infections caused by abdominal pain,
staphlococci and stomach upset,
streptococci. Now they are skin rash,
They are used to wideley used to for hives,
defend against different bacterial itching, and
Odin Debrovner Amoxicillin Amoxll Penicillin 1972 bacterial infections infections. black "hairy" tongue
Amoxicillin is in the
beta-lactam One common and unusual
antimicrobials class. reason amoxicillin is
Beta-lactams bind to prescribed is to allow
penicillin-binding people with artificial heart
proteins that contain a valves to visit the dentist
process known as for a routine teeth
transpeptidation, cleaning. Without
which is a cross- amoxicillin, patients with
linking process in cell an artificial heart valve can
wall synthesis. This develop a heart infection, Of all the antibiotics,
process leads to the such as endocarditis, Common side effects for amoxicillin are diarrhea, amoxicillin is the
activation of autolytic because bacteria can stomach aches, headaches, abnormal taste, and antibiotic that is most
Amoxil / Moxatag / enzymes in the enter the bloodstream skin rash. frequently given to
Derek Sadorra Amoxicillin Trimox Penicillin 1972 bacteria cell wall. during the visit. children.

binding to 50s used to fight off serious vomiting// diarrhea// stomach pain// joint pain// it will not work fro virus
ribosomal subunit of infections caused by vaginal itching, discharge// skin rash// heart burn// infection like common
Xitlali Nunez clindamycin cleocin lincomycin 1986 bacteria bacteria sore throat cold or flu
Skin rashes, nausea, vomiting, and Penicillins was an
sinus and chest infections, itching/swelling skin. accidental discovery in
A Amoxil, Polymox, invades call wall ear infections,dental 1928 by Dr. Alexander
Malina Weerts Amoxicillin Trimox, Wymox Penicillins 1972 and kills infection infections Fleming.
Most commonly taken Treats many infections
by pill on an empty including chest infections,
stomach. skin infections, dental
Reccomended either infections and STIs.
1-2 hours before/after Doxycycline is most
a meal, and is taken commonly used as acne
Discovered in 1960s but either 1-2 times a day medication, espcieally for Is effective against both
Doryx, Periostat, & became FDA approved depending on rosacea. It can also be headaches, nausea, diarrhea, vomitting, and upset gram positive and gram
Alana Choe Doxycycline Vibramycin Tetracycline in 1967 prescription used for Malaria. stomach negative bactera

Interfere with bacterial

enzymes DNA gyrase
and topoisomerase IV This is sometimes used
activities and prevent to reduce the
multiplication of Mainly use for treating Change of hearing, change of vision, respiratory development of drug-
Thanh Nguyen Lomefloxacin Maxaquin Flouroquinolones 1989 bacteria cell. urinary tract infections. infection, skin rashes and swelling (if allergic). resistance bacteria.

Uesd to treat infections

such as Pneumonia it has
Breaks down the wall also been used to treat Can come in a pill or
Adrian Ochoa Amoxicillin Amoxil Penicillins 1972 in Bacteria Lyme disease -Nausea , vomiting, Headache, Rash liquid form
 Antibiotics
Pharmacological Discovery/Development Other/Anything
Student Name/Contributer Generic Name Brand Name Category Date Method of Action Medical Uses Common Side Effects Interesting?
-Ear, nose, and throat
infections
-Genitourinary tract
infections
-Skin and skin structure
infections
By binding proteins -Lower respiratory tract If you are taking
and inhibiting certain infections amoxicillin long-term
processes in bacterial -Sexually transmitted - Diarrhea your doctor may need
cells, this causes the diseases - Upset stomach to periodically order
cell walls to break -Helicobacter pylori - Headache blood tests and check
Aminopenicillin, down and destroy the infection - Abnormal taste sense. your kidney and liver
Celia Sotelo Amoxicillin Amoxil®, Trimox® Beta-lactam 1972 bacteria. - Skin rash. function.

It's used to treat infections

such as chest infections,
is intended to stop the skin infections, rosacea,
growth of bacteria by dental infections and
allosterically binding sexually transmitted
to the 30S prokaryotic infections like sti’s , as well Diarrhea , Difficulty swallowing , Drug rash,
Vibramycin, in the early 1960s by ribosomal unit during as a lot of other rare Esophageal ulcer , Esophagitis , Facial redness ,
scarlett gutierrez doxycycline Monodox Pfizer Inc. protein synthesis infections. Headache , Hives.

Amoxicillin is the
class of beta-lactams
antimicrobials, they
act by binding to
penicillin-binding
proteins that inhabit a This medication is used for
cross linking process treating and infections
in the cell wall such as bronchitis,
this The drug was synthesis leading to tonsillitis, pneumonia, and
discovered in 1972 by a activation of autolytic most commonly used for Side effects of using this drug can be, stomach
amoxil / trimox bete-lactam, and scientist in the beecham enzymes in the treating bacteria in the ear, upset, diarrhea, headaches, skin rash, adormal
asaisha williams amoxicillin /moxatag aminopenicillin research laboratories bacteria cell wall nose, throat, or chest. taste sense, and viginal yeast infection.

Intended to stop the

growth of bacteria by
allosterically binding Helps reduce the amount
to the 30s prokaryotic of Propionibacterium Side effects are loss of appetite, nausea, diarrhea,
Doryx, Doxy, Discovered in 1960s, ribosomal unit during bacteria on my skin sensitivity to sun, temporary discoloration of adult This medication is also
Ivory Daly Doxycycline Adoxa, etc Tetracycline approved 1967 protien synthesis creating the acne. teeth used to prevent malaria

blood in urine/ringing noise in ear/feeling tiredness

infections-treat colitis-kills or weakness/feeling constant movement of self or
Aylim Santos Vancomycin vancocin Glycopetide discoverd in 1950's bacteria in intestines surroundings

Doxycycline is
generally
bacteriostatic
against a wide
variety of
organisms, both
gram-positive and
Nael Tesfamariam Doxycycline Doryx Tetracycline 1960's gram-negative

Brandon Abarca Cefepime Maxipime Cephalosporin

 Antibiotics
Pharmacological Discovery/Development Other/Anything
Student Name/Contributer Generic Name Brand Name Category Date Method of Action Medical Uses Common Side Effects Interesting?
Reduces number of Clindamycin is used for "clindamycin is one of the antibiotics that has the
bacteria by stopping bacterial infections in the greatest risk of causing Clostridium difficile"
it’s growth, and/or lungs, skin, blood, female (Hirsch, Healthline) When used for infections in Clindamycin has been
kills the bacteria (on reproductive organs, and internal organs, side effects may include nausea, used as treatment for
Chelsea Uong Clindamycin Cleocin Lincomycin 1966 skin). other internal organs. vomiting, diarrhea, and stomach pain. dental procedures.
ear nose and throat diarrhea. stomach upset. headache. abnormal
Kyle gregoire Amoxicillin Amoxil,Trimox Aminopenicillan 1974 infections,std's taste sense. skin rash

Used to treat certain Treats certain infections

infections caused by like pnemonia and other Some side effects can be, Nausea, Vomiting,
bacteria and works by respirartory infections Diarrhea, Heartburn, Stomach pain, Dizziness, and
Heidy Rodriguez Cefalexin Cephalexin, Keflex Cephalosporin 1967 killing the bacteria. caused by bacteria extreme tiredness.

Binding proteins and

inhibiting certain
processes in bacterial
cells, this causes the
cell walls to break
down and destroy the throat infections, ear nose, Upset stomach, Headache, Diarrhea, Skin rah,
Daisy Rodriguez Amoxicillin Amoxil,Trimox Aminopenicillan 1974 bacteria. and stds and Abnormal taste sence

only works on bacterial

stops the growth of infections, it will not work
Jared Hayes clindamycin Cleocin lincomycin 1986 bacteria on viruses Nausea, vomiting, stomach pain, mild skin rash.

it inhibits the third and Treats certain infections

Cephalosporin last stage of bacterial for example bone diseases diahrrea, severe pain, skin rash, uneven
Citlaly Garcia Ceftizoxime Cefizox Antibacterial 2007 cell wall synthesis. mostly treated for bacteria heartbeats, fever flu type symptos

In 1975 they thought is

Done at night with a This is affective for getting had therapuedtic
clean face. This rid of acne on yout face. It propeeties in treating
breaks down the works to prevent it from You can expierents mild redness on your cheeks, wrinking skin and
Madison Latimer Tretinion Cream Tretinion, Retin-A retiniods 1971 bacetia walls coming back to. burning, dryn face warts.
pneumonia; bronchitis and
infections of the ears, upset stomach
It acts through the nose, throat, urinary tract, headache Amoxicillin is an
inhibition of cell wall and skin. It is also used in antibiotic that kills
biosynthesis that combination with other
abnormal taste sense bacteria by inhibiting
leads to the death of medications to eliminate skin rash the synthesis of cell
Ashley Camacho Amoxicillin Amoxil aminopenicillin 1972 the bacteria H. vaginal yeast infection wall mucopeptides
 Antibiotics
Student Pharmacological Discovery/Development Common Side Other/Anything
Name/Contributer Generic Name Brand Name Category Date Method of Action Medical Uses Effects Interesting?
Concerns about
allergic reactions,
such as skin rash
(hives), swelling of
lips, tongue, face,
etc. Not
recommended for Helpful against both
people under 18. Gram + & 1 bacteria
Also reported (and effective against
Inhibits Bacterial DNA Active against acute nausea, vomiting, MRSA (Resistant
Mr. M Delafloxacin Baxdela® Fluoroquinolone 2017 replication bacterial skin infections headache. strains))
Amoxicillin contains
Beta-lactams which
bind to penicillin's
proteins then inhibit a
process known as
transpeptidation.
Transpeptidation is a
chemical reaction
within the body where
amino acid or peptide
residue is transferred Diarrhea, Upset
from one amino
compound to the next.
Used to treat bacterial stomach, Think about it like
The transpeptidation infections such as Headache, this, amoxicillin is the
process activates the chest infections, UTI's. Abnormal taste, childrens, watered
Moxatag, Amoxil, Penicillinase- autolytic enzymes in Often treats childrens Rashes, Yeast down version of
Kaeli Graves Amoxicillin Trimox Sensitive Penicillin 1972 the bacterica's cell wall. ear infections. infection. penicillin.

Clidamycin works by
binding together the Used to treat serious Common sie
50s ribosomal of infections caused by effects may
bacteria it disrupts anaerobic bacteria. include nausea, Should only take if
protien synthesis to Most effective agaisnt vomitting, stomach the infection is
inhibit early chain various skin and soft pain, and a mild serious or else it may
Jennifer De La Torre Clidamycin Cleocin Lincosamides 1970 elognation. tissue infections. skin rash. be fatal.

May cause rare but

very serious side
effects: Hypersensitivity
syndrome, Autoimmune
hepatitis, and Lupus.
It can also be used to
Other side effects
include nausea and treat acne by
Effective against
Involves attaching to inflammation, microglial vomiting, diarrhea, decreasing a certain
the bacterial 30S changes in the color of oily substance that
activation, matrix your urine, ringing in
ribosomal subunit metalloproteinases, nitric causes acne and kills
your ears, hair loss, dry
Dynacin, Minocin, and preventing oxide production, and mouth, and/or tongue the bacteria that
Tien Ngo Minocycline Monodox Tetracycline 1961 protein synthesis apoptotic cell death swelling. infects pores.

Used for ear, nose, skin, Tooth enamel

and throat infections, defects, diarrhea,
Inhibits bacterial cell stomach ulcers, and rashes. Some
Aminopenicillin, Beta- wal synthesis during sexually transmitted people may also
Kaya Santiago Amoxicillin Amoxil, Trimox lactam 1972 multiplication diseases. be allergic.
 Antibiotics
Student Pharmacological Discovery/Development Common Side Other/Anything
Name/Contributer Generic Name Brand Name Category Date Method of Action Medical Uses Effects Interesting?
Mescaline is
phenethylamine
akaloid that is
phnethylamine thats
put into 3 postions To give visual anxiety and fear, Its fairly new and
Phychedelic put by 4 and 5 by hullucinations and dizziness, arent alot of research
Mia Mescaline CAS hallucinogen 2005-03--25 methoxy groups alerted conciosuses weakness ect. on it.

Gerpafloxacin was
Grepafloxacin (trade withdrawn from
name Raxar, Glaxo markets due to the
Wellcome) was an oral side affect QT
broad-spectrum side affects Interval on the
Gerpafloxacin is an fluoroquinolone include headace electrocardiogram
oral broad-spectrum antibacterial agent dizzyness, which lead to cardiac
third generation that is used to treat used to treat bacterial abdomial pain, and effects and sudden
Ada Moreno Gerpafloxacin Raxar fluoroquinolone 1999 baterical infections. infections. nasusa. death

Carboxypeptidases,
endopeptidases, and
transpeptidases clings
onto the ceftriaxone in the
bacterial cytoplasmic Ceftriaxone is an injection
membrane. These used to treat certain
enzymes are included in infections such as
cell wall synthesis and cell gonorrhea, pelvic
division. When these inflammatory disease,
enzymes are bound meningitis, and infections of Severe effects:
together with ceftriaxone, the lungs, ears, skin, urinary Pain/tenderness,
it causes cell death that tract, blood, bones, joints, pale skin, diarhea
the bacteria produce in and abdomen. It is also used
Serious Effects:
the defective cell walls for certain surgeries to
Cephalosporins- 3rd because the enzymes are prevent infections that may Rash, seizures
Erica Tran Ceftriaxone Rocephin generation 1982 losing activity. happen during the operation. and chest pain

side effects:
nausea,vomiting,
upset stomach,
diarrhea, rust-
colored or
Nitrofurantion is used brownish urine,
to treat treat urinary vaginal itching or
tract infection (UTI’s), discharge,
Furadantin, which includes cystic headache, and
Nitrofurantoin Macrobid, - killing bacteria that and kidney infection. gas.
Camila Gallegos Macrodantin antimicrobials 1953 causes infection
-Sulfamethoxazole was -Prevents urinary tract -Easily attained -Skin problems
gained popularity in 1939 -used to kill bacteria infections (like shigella) sunburns -Blood Problems
-sulfatrim Pediatric when Gerhard Domagk that cause infections -Pneumocystis -Skin problems (rare)
-Bactrim - won his nobel prize -Lower the number pneumonia -If taking this with -Liver problems
Bactrim DS - -Antibiotic & -TMP was introduced in of plateletes in hte -Middle ear infections other medications (rare)
Sulfamethoxazole- SMZ-TMP Sulfonamide finland in 1972 then was body -Is also used to help or drinking could -Aseptic meningitis
Nallely Trimethoprim Pediatric Combination introduced to treatment prevent pneumonia be harmful and (rare) are rave side
patients during chemotherapy change lab results effects you can get
-Sold in 1974 and started -Effectiveness i'm not and being over the
to gain more popularity in 100% sure but it's age of 65 can lead
2017 being used more and to more side
more effects
 Antibiotics
Student Pharmacological Discovery/Development Common Side Other/Anything
Name/Contributer Generic Name Brand Name Category Date Method of Action Medical Uses Effects Interesting?
Nausea, vomiting,
diarrhea for those
who are allergic,
used to treat many fungal infection (
works by stopping different types of oral or vaginal,
the growth of the infection caused by what ever the case
Ximena Solano Amoxillin Moxatag penticillin-type 1972 bacteria bacteria may be)

The concerns of
taking
Trovafloxacin
antibiotic could
Trovafloxacin is used to cause side effects
The Trovafloxacin treat infections such as such as abdominal
antibiotic has been pneumonia, pain, diarrhea,
approved by the U.S. food complicated abdominal dizziness,
and drug administration, to infections, gynecologic headache,
be used for patients 18 or and pelvic infections, lightheadedness,
older, in 1997 in the month and even skin nausea, vomiting,
Celeste Almaraz Trovafloxacin Trovan Pfizer of December. infections. and also itching.

Taking these
medications comes
with side effects. Some
Medical uses that side effects include
Flucloxacillin has is being diarrhoea that may
The method of action of able to treat any ear contain mucus or
Flucloxacillin is that it is infections, skin infections, blood, pale poo with
Flucloxacillin was first able to inhabit the third bone infections, heart and dark urine, bruising,
This antibiotic can be discovered in 1961, but wasn’t and last stage of the chest infections. But can discolored skin and
Flopen, Floxapen, and found in the Penicillins commonly used in the U.S or bacterial cell wall only be accessible by a possibly joint or
Phung Lai Flucloxacillin Staphcillin. category. Canada until as of 2011. synthesis. doctor. muscle pain.

Oxacillin injection is
used to treat infections
Oxacillin, like other caused by certain
beta-lactam bacteria. Oxacillin Nausea, upset
antibiotics, binds injection is in a class of stomach, vomiting,
penicillin-binding medications called mild diarrhea;
proteins (PBPs) that penicillins. It works by swollen, black, or
weaken or interfere killing bacteria. "hairy" tongue; or.
with cell wall Antibiotics such as thrush (white
formation. After oxacillin injection will patches or inside
binding to PBPs, the not work for colds, flu, your mouth or
cell wall weakens or or other viral infections. throat)
Lizbeth Ruiz Oxacillin Prostaplin Penicills 1960s undergoes lysis.

Vomiting, bitter
taste, chills, drug
fever, red rashes
This antibiotic used to treat on the face, and
1956 but emerged in inhibits cell wall infections caused by low blood
Marbella Flores Vancomycin Vancocin clinical use in 1958
glycopeptide antibiotics synthesis. bacteria. pressure.
 Antibiotics
Student Pharmacological Discovery/Development Common Side Other/Anything
Name/Contributer Generic Name Brand Name Category Date Method of Action Medical Uses Effects Interesting?

1972, Beecham
Research
Amoxil®, Aminopenicillin, Laboratories,
Estefany Godoy Amoxicillin Trimox® Beta-lactam United Kingdom

The common side-

effects are
It is used for infections nausea, vomiting,
Erythrocin; and skin problems abdominal
Erythrolar; such as acne and discomfort, and
Abril Solano Erythromycin Erythroped Macrolide 1952 rosacea diarrhea