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Git MCQ

The document contains 19 multiple choice questions about antiulcer medications and treatments for Helicobacter pylori. It tests knowledge on which drugs affect the cytochrome P450 system, classes of drugs that can eradicate H. pylori, common antacids and their side effects, H2 receptor antagonists, treatments for H. pylori infection, and the effectiveness of various combination therapies.

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Padmavathi C
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10K views27 pages

Git MCQ

The document contains 19 multiple choice questions about antiulcer medications and treatments for Helicobacter pylori. It tests knowledge on which drugs affect the cytochrome P450 system, classes of drugs that can eradicate H. pylori, common antacids and their side effects, H2 receptor antagonists, treatments for H. pylori infection, and the effectiveness of various combination therapies.

Uploaded by

Padmavathi C
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOC, PDF, TXT or read online on Scribd
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Question # 1

More likely to affect the cytochrome P450 drug metabolizing system:

A) ranitidine (Zantac)
B) cimetidine (Tagamet)

Question # 2 (Multiple Choice)


Only class of antiulcer drugs that can eradicate Helicobacter pylori and cure
associated gastritis:

A) sucralfate (Carafate)
B) colloidal bismuth
C) H2 blockers
D) Anticholinergic agents

Question # 3 (Multiple Choice)

Antacid: melt-alkali syndrome:


A) aluminum hydroxide
B) magnesium hydroxide
C) calcium carbonate
D) sodium bicarbonate
Question # 4 (True/False) Reduces basal unstimulated gastric acid secretion;
enhanced mucosal resistance to injury-- prostaglandins (PGE1/PGE2)

A) true
B) false
Question # 5 (Multiple Choice) Antacid: effective, but associated with systemic
alkalosis

A) calcium carbonate
B) sodium bicarbonate
C) magnesium hydroxide
D) aluminum hydroxide
Question # 6 (Multiple Choice) Antacid: most likely to cause systemic phosphate
depletion:
A) sodium bicarbonate
B) calcium carbonate
C) magnesium hydroxide
D) aluminum hydroxide
Question # 7 (Multiple Choice) Monotherapy effectiveness in eradication of H.
pylori-- bismuth compounds

A) 5%
B) 20%
C) 50%
D) 90%
Question # 8 (Multiple Answer) Omeprazole (Prilosec) and lansoprazole approved
for clinical treatment of:

A) duodenal ulcer
B) erosive gastritis
C) Zollinger-Ellison syndrome and other gastric acid hypersecretory states
Question # 9 (Multiple Choice) Side effect profile-- antiulcer medication: urinary
retention, blurred vision, xerostromia,:

A) ranitidine (Zantac)
B) atropine
C) nifedipine (Procardia, Adalat)
D) sucralfate (Carafate)
Question # 10 (Multiple Answer) Examplesof H2 (histamine receptor Type II)
antagonists:

A) cimetidine (Tagamet)
B) ranitidine (Zantac)
C) nizatidine (Axid)
D) famotidine (Pepcid)
E) terfenadine
Question # 11 (Multiple Choice) Mechanism of action: cytoprotection, binds to
the ulcer base, antibacterial effect:

A) metronidazole (Flagyl)
B) tetracycline (Achromycin)
C) bismuth compounds
D) ranitidine (Zantac)
E) omeprazole (Prilosec)
Question # 12 (Multiple Answer) Drug(s) used iin eradication of Helicobacter
pylori infection:

A) bismuth compounds
B) metronidazole (Flagyl)
C) clarithromycin (Biaxin)
D) omeprazole (Prilosec)
E) amoxicillin (Amoxil Polymox)
Question # 13 (Multiple Choice) Most widely used antacid in treating ulcer
disease:

A) sodium bicarbonate
B) calcium carbonate
C) magnesium hydroxide
D) aluminum hydroxide
E) combination of aluminum hydroxide and magnesium hydroxide
Question # 14 (Multiple Choice) Treatment of gastric a disease: atropine vs.H2-
receptor blockers -- atropine is:

A) more effective than H2 receptor blockers


B) less effective than H2 receptor blockers
C) equally effective
Question # 15 (Multiple Choice) Drawbacks of "triple therapy" {bismuth
compounds + metronidazole (Flagyl) + tetracycline (Achromycin)}in treating
peptic ulcer disease:

A) patient compliance (2 week treatment = 200 tablets)


B) side effects
C) both
D) neither
Question # 16 (Multiple Choice) Antacid: constipation

A) aluminum hydroxide
B) magnesium hydroxide
Question # 17 (Multiple Choice) Most successful protocol for eradication of H.
pylori/treatment of peptic ulcer disease:

A) bismuth monotherapy
B) therapy using bismuth compounds, metronidazole (Flagyl), and amoxicillin
(Amoxil Polymox) in combination -triple therapy
C) bismuth compounds and amoxicillin (Amoxil Polymox)
D) all of the above equally effective
Question # 18 (Multiple Choice) Antacid: loose stools

A) aluminum hydroxide
B) magnesium hydroxide
C) both
D) neither
Question # 19 (Multiple Choice) Eradication of H. pylori effectiveness for bismuth
compounds when using combination with antibiotics:

A) 5%
B) 20%
C) 50%
D) 80%
E) 95%

Correct Answers
1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19
Question # 1 (Multiple Choice) More likely to affect the cytochrome P450 drug
metabolizing system:

Answer: (B) cimetidine (Tagamet)

BACK
Question # 2 (Multiple Choice) Only class of antiulcer drugs that can eradicate
Helicobacter pylori and cure associated gastritis:
Answer: (B) colloidal bismuth

BACK
Question # 3 (Multiple Choice) Antacid: melt-alkali syndrome:

Answer: (C) calcium carbonate

BACK
Question # 4 (True/False) Reduces basal unstimulated gastric acid secretion;
enhanced mucosal resistance to injury-- prostaglandins (PGE1/PGE2)

Answer: True

BACK
Question # 5 (Multiple Choice) Antacid: effective, but associated with systemic
alkalosis

Answer: (B) sodium bicarbonate

BACK
Question # 6 (Multiple Choice) Antacid: most likely to cause systemic phosphate
depletion:

Answer: (D) aluminum hydroxide

BACK
Question # 7 (Multiple Choice) Monotherapy effectiveness in eradication of H.
pylori-- bismuth compounds

Answer: (B) 20%

BACK
Question # 8 (Multiple Answer) Omeprazole (Prilosec) and lansoprazole approved
for clinical treatment of:

(A) duodenal ulcer


(B) erosive gastritis
(C) Zollinger-Ellison syndrome and other gastric acid hypersecretory states
BACK
Question # 9 (Multiple Choice) Side effect profile-- antiulcer medication: urinary
retention, blurred vision, xerostromia,:

Answer: (B) atropine

BACK
Question # 10 (Multiple Answer) Examplesof H2 (histamine receptor Type II)
antagonists:

(A) cimetidine (Tagamet)


(B) ranitidine (Zantac)
(C) nizatidine (Axid)
(D) famotidine (Pepcid)
BACK
Question # 11 (Multiple Choice) Mechanism of action: cytoprotection, binds to
the ulcer base, antibacterial effect:
Answer: (C) bismuth compounds

BACK
Question # 12 (Multiple Answer) Drug(s) used iin eradication of Helicobacter
pylori infection:

(A) bismuth compounds


(B) metronidazole (Flagyl)
(C) clarithromycin (Biaxin)
(D) omeprazole (Prilosec)
(E) amoxicillin (Amoxil Polymox)
BACK
Question # 13 (Multiple Choice) Most widely used antacid in treating ulcer
disease:

Answer: (E) combination of aluminum hydroxide and magnesium hydroxide

BACK
Question # 14 (Multiple Choice) Treatment of gastric a disease: atropine vs.H2-
receptor blockers -- atropine is:

Answer: (B) less effective than H2 receptor blockers

BACK
Question # 15 (Multiple Choice) Drawbacks of "triple therapy" {bismuth
compounds + metronidazole (Flagyl) + tetracycline (Achromycin)}in treating
peptic ulcer disease:
Answer: (C) both

BACK
Question # 16 (Multiple Choice) Antacid: constipation

Answer: (A) aluminum hydroxide

BACK
Question # 17 (Multiple Choice) Most successful protocol for eradication of H.
pylori/treatment of peptic ulcer disease:

Answer: (B) therapy using bismuth compounds, metronidazole (Flagyl), and


amoxicillin (Amoxil Polymox) in combination -triple therapy

BACK
Question # 18 (Multiple Choice) Antacid: loose stools

Answer: (B) magnesium hydroxide

BACK
Question # 19 (Multiple Choice) Eradication of H. pylori effectiveness for bismuth
compounds when using combination with antibiotics:

Answer: (E) 95%

BACK

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