Chemcial Hygiene Plan Appendix H Classes of Carcinogenic Compounds

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Chemcial Hygiene Plan Appendix H

Classes of Carcinogenic Compounds


(* select carcinogens)
Alkylating agents: a-halo ethers

*bis(chloromethyl)ether
*methyl chloromethyl ether

Alkylating agents: sulfonates

*1,4-butanediol dimethanesulfonate
diethyl sulfate
dimethyl sulfate
ethyl methanesulfonate
methyl methanesulfonate
methyl trifluoromethanesulfonate
1,3-propanesultone

Alkylating agents: epoxides

*ethylene oxide
diepoxybutane
epichlorohydrin
propylene oxide
styrene oxide

Alkylating agents: aziridines

*ethylenimine
2-methylaziridine

Alkylating agents: diazo, azo, and azoxy compounds

4-dimethylaminoazobenzene

Alkylating agents: electrophilic alkenes and alkynes

*acrylnotrile
acrolein
ethyl acrylate

The Ohio State Univeristy Office of Environmental Health & Safety - Chemical Hygiene Plan
Appendix H - Classes of Carcinogenic Compounds- Page 1
Revision 4-06
Chemcial Hygiene Plan Appendix H
Classes of Carcinogenic Compounds
(* select carcinogens)
Acylating agents

*β-propiolactone
β-butyrolactone
dimethylcarbamoyl chloride

Organohalogen compounds

*1,2-dibromo-3-chloropropane
*mustard gas (bis(2-chloroethyl)sulfide)
*vinyl chloride
carbon tetrachloride
chloroform
3-chloro-2-methylpropene
1,2-dibromoethane
1,4-dichlorobenzene
1,2-dichloroethane
2,2-dichlorethane
1,3-dichloropropene
hexachlorobenzene
methyl iodide
tetrachloroethylene
trichloroethylene
2,4,6-trichlorophenol

Hydrazines

hydrazine (and hydrazine salts)


1,2-diethylhydrazine
1,1-dimethylhydrazine
1,2-dimethylhydrazine

N-nitroso compounds

*N-nitrosodimethylamine
N-nitroso-N-alkylureas

Aromatic amines

*4-aminobiphenyl
*benzidine (p,p’-diaminobiphenyl)
*α-naphthylamine
*β-naphthylamine
aniline
The Ohio State Univeristy Office of Environmental Health & Safety - Chemical Hygiene Plan
Appendix H - Classes of Carcinogenic Compounds- Page 2
Revision 4-06
Chemcial Hygiene Plan Appendix H
Classes of Carcinogenic Compounds
(* select carcinogens)
o-anisidine (2-methoxyaniline)
2,4-diaminotoluene
o-toluidine

Aromatic hydrocarbons

*benzene
benz[a]anthracene
benzo[a]pyrene

Nathural products (including antitumor drugs)

adriamycin
aflatoxins
bleomycin
cisplatin
progesterone
reserpine
safrole

Miscellaneous organic compounds

*formaldehyde (gas)
acetaldehyde
1,4-dioxane
ethyl carbamate (urethane)
hexamethylphosphoramide
2-mitropropane
styrene
thiourea
thioacetamide

Miscellaneous inorganic compounds

*arsenic and certain arsenic compounds


*chromion and certain chromium compounds
*thorium dioxide
berylluim and certain berylluim compounds
cadmuim and certain cadmium compounds
lead and certain lead compounds
mickel and certain mickel compounds
selenium sulfide

The Ohio State Univeristy Office of Environmental Health & Safety - Chemical Hygiene Plan
Appendix H - Classes of Carcinogenic Compounds- Page 3
Revision 4-06

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