Pathophysiology of Atrial Septal Defect

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PATHOPHYSIOLOGY OF ATRIAL SEPTAL DEFECT

Predisposing factors: Precipitating factors: Etiology:


-Genetics Modifiable: Non-modifiable : - Unknown
-Age and Sex (F-M ; 2:1) -Tobacco -Rubella infection (German Measles)
-Alcohol use -Teratogrens
-Exposure to certain substance
-HPN

Foramen ovale after birth filed to septal entriely

Defect in the inter-atrial septum ATRIAL SEPTAL DEFECT

Foramen ovale after birth filed to septal entirely


Dilated left atrium and right
ventricle
(echocardiogram)
Blood draws back to from left-to-the-right atrium
(Left-to-right shunt)

Pulmonary congestion and


mild cardiomegaly
(chest-xray)

s/sx: Increase volume and pressure in the Mixing of venous and arterial
right chambers of the heart blood
dyspnea, cough, frothy
sputum, edema, chest
pain, palpitations
Difficulty of breathing Pulmonary hypertension Decrease oxygenated blood
Hypo-perfusion
in the circulation

Organ anoxia
Ventricular hypertrophy
Decrease oxygenated blood
in the circulation

Decrease oxygen Low Hgb


Mechanical Ventilation Low Hct
concentration in the blood

s/sx:
pale palpebral
Mucosal inflammation and hypersecretion conjunctiva and nail
beds

Prolonged stay in the hospital Secretions are retained

Hospital-Acquired pnuemonia

s/sx increased wbc

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